CN214334801U - Sample introduction cold trap and full two-dimensional chromatographic modulation system - Google Patents
Sample introduction cold trap and full two-dimensional chromatographic modulation system Download PDFInfo
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- CN214334801U CN214334801U CN202120425684.5U CN202120425684U CN214334801U CN 214334801 U CN214334801 U CN 214334801U CN 202120425684 U CN202120425684 U CN 202120425684U CN 214334801 U CN214334801 U CN 214334801U
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Abstract
The utility model discloses a advance kind cold trap and full two-dimensional chromatogram modulation system belongs to gas chromatography modulation field. The utility model provides a kind and advances a kind cold trap and full two-dimensional chromatogram modulation system, includes six-way diverter valve, still includes: the one-dimensional chromatographic column is connected with two valve ports on the six-way switching valve; the thermal modulator is connected with two valve ports on the six-way switching valve; the detector is connected with one valve port on the six-way switching valve; the two-dimensional chromatographic column is connected between the six-way switching valve and the detector; the six-way switching valve is provided with a valve port A, a valve port B, a valve port C, a valve port D, a valve port E and a valve port F; the utility model discloses utilize cold trap and hot modulator difference in sample analysis time, carry out the valve at suitable time and switch to realized that hot modulator accomplishes the cold trap enrichment when advancing the appearance, and at the back analysis stage of advancing the appearance, accomplish the hot modulation function of full two-dimentional gas chromatography, effectively simplified the system, improved efficiency.
Description
Technical Field
The utility model relates to a gas chromatography modulation technology field especially relates to a advance kind cold-trap and full two-dimensional chromatogram modulation system.
Background
The gas chromatograph and the gas chromatograph-mass spectrometer are used for separating chemical components in a mixture sample to realize qualitative and quantitative functions, are common instrument equipment in modern analysis laboratories, and a conventional gas chromatograph or the gas chromatograph-mass spectrometer uses one chromatographic column to separate an organic mixture. If the mixture contains too many components or the interfering matrix is too complex, partial or complete overlapping of the chromatographic peaks, i.e.co-efflux, occurs, which can make subsequent detection difficult; the full-two-dimensional gas chromatography is characterized in that substances separated by a first chromatographic column are continuously collected by an additional modulator device at a fixed time period, then are fed into a second chromatographic column with different properties, and are subjected to secondary independent separation at the same time period, so that the two-dimensional separation of all components of a mixture is realized.
If the components in the mixture do have two-dimensional chemistry matching that of the two chromatography columns used, it is possible that the co-effluent from one column will be completely separated on the second column, and thus, two-dimensional gas chromatography is a powerful means of performing high-efficiency separations on complex mixtures.
The thermal modulation technology is a function of collecting substances separated from a first chromatographic column and rapidly feeding the substances to a second chromatographic column by periodically refrigerating and heating a sample, and is the most main full-two-dimensional gas chromatography modulation technology at present due to excellent modulation effect; the gas chromatograph or the gas chromatograph-mass spectrometer can select various sample introduction modes.
The thermal modulator for the full two-dimensional gas chromatography is a cold trap in principle, the distillate of a first chromatographic column is enriched and then is rapidly injected into a downstream second chromatographic column, only once enrichment and injection are needed during sample injection when the thermal modulator is used for the cold trap, and continuous enrichment and sample injection are needed according to a set modulation period when the thermal modulator is used for the full two-dimensional gas chromatography; because the cold trap is positioned at the front end of the first chromatographic column, and the thermal modulator is positioned between the first chromatographic column and the second chromatographic column, if the cold trap and the full-two-dimensional gas chromatography technology are combined, two modulators need to be installed at two different positions, and the complexity and the cost of the system are increased.
The patent of the utility model discloses a system that only needs a hot modulator just can realize advancing kind cold trap and full two-dimensional chromatogram modulation simultaneously. In the system, the cold trap and the thermal modulator are used for carrying out valve switching at proper time by utilizing the difference of the sample analysis time, so that the thermal modulator finishes cold trap enrichment during sample injection, and finishes a full two-dimensional gas chromatography thermal modulation function in an analysis stage after sample injection, thereby effectively simplifying the system and improving the efficiency
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the problems existing in the prior art and providing a sample introduction cold trap and a full two-dimensional chromatographic modulation system.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model provides a kind and advances a kind cold trap and full two-dimensional chromatogram modulation system, includes six-way diverter valve, still includes:
the one-dimensional chromatographic column is connected with two valve ports on the six-way switching valve;
the thermal modulator is connected with two valve ports on the six-way switching valve;
the detector is connected with one valve port on the six-way switching valve;
and the two-dimensional chromatographic column is connected between the six-way switching valve and the detector.
Preferably, the six-way switching valve is provided with a valve port A, a valve port B, a valve port C, a valve port D, a valve port E and a valve port F, the one-dimensional chromatographic column is connected with the valve ports F of the valve port C, and the thermal modulator is connected with the valve ports B and the valve port E.
Preferably, the two-dimensional chromatographic column and the detector are connected with a valve port D.
Preferably, a sample is connected to the valve port A of the six-way switching valve.
Preferably, a valve port A on the six-way switching valve is communicated with a valve port B, a valve port C on the six-way switching valve is communicated with a valve port D, and a valve port E on the six-way switching valve is communicated with a valve port F.
Preferably, a valve port B on the six-way switching valve is communicated with a valve port C, a valve port D on the six-way switching valve is communicated with a valve port E, and a valve port F on the six-way switching valve is communicated with a valve port A.
Compared with the prior art, the utility model provides a advance kind cold-trap and full two-dimensional chromatogram modulation system possesses following beneficial effect:
1. this advance kind cold trap and full two-dimensional chromatogram modulation system includes: a one-dimensional chromatographic column, a thermal modulator, a two-dimensional chromatographic column and a six-way switching valve, wherein the six-way switching valve is positioned at a first position when a sample is injected, namely a cold trap position, at the moment, the sample firstly passes through the thermal modulator, the thermal modulator firstly carries out a modulation process, the sample is trapped by refrigeration, or the collected sample is quickly injected into the one-dimensional chromatographic column through a cold area of the thermal modulator after a period of time, or the collected sample is moved to a hot area to be released, the six-way switching valve is switched to the second position after the sample completely enters the one-dimensional chromatographic column and the time is probably several seconds, namely the modulator position, and simultaneously the thermal modulator recovers the normal modulation program and modulates according to the set modulation period, at this time, the carrier gas firstly enters the one-dimensional chromatographic column, then the gas passes through a thermal modulator and then enters a two-dimensional chromatographic column and a detector to form a normal full two-dimensional gas chromatographic flow path.
2. According to the sample introduction cold trap and the full two-dimensional chromatographic modulation system, the six-way switching valve can rotate the valve body in a manual, pneumatic or electric mode, so that the communication direction between ports is changed, and the switching of a flow path is realized.
3. The sampling cold trap and the full two-dimensional chromatographic modulation system can also use switching valves with eight-way ports, ten-way ports or more ports, and are more convenient to use.
The device does not relate to the part all the same with prior art or can adopt prior art to realize, the utility model discloses utilize cold trap and hot modulator difference in sample analysis time, carry out the valve switching in suitable time to realized that hot modulator accomplishes the cold trap enrichment when advancing the appearance, and in the analysis stage after advancing the appearance, accomplish full two-dimensional gas chromatography thermal modulation function, effectively simplified the system, improved efficiency.
Drawings
FIG. 1 is a schematic structural diagram of a six-way switching valve in a sample injection cold trap and full two-dimensional chromatographic modulation system according to the present invention at the position of the cold trap;
fig. 2 is the structure diagram of the six-way switching valve in the sample injection cold trap and the full two-dimensional chromatographic modulation system when the six-way switching valve is located at the modulator position.
In the figure: 1. a one-dimensional chromatographic column; 2. a two-dimensional chromatographic column; 3. a six-way switching valve; 4. a thermal modulator; 5. a detector; 6. and (3) sampling.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Referring to fig. 1-2, a sample introduction cold trap and full two-dimensional chromatography modulation system comprises a six-way switching valve 3, and further comprises:
the one-dimensional chromatographic column 1 is connected with two valve ports on the six-way switching valve 3;
the thermal modulator 4 is connected with two valve ports on the six-way switching valve 3;
the detector 5 is connected with one valve port on the six-way switching valve 3;
the two-dimensional column 2 is connected between the six-way switching valve 3 and the detector 5.
The six-way switching valve 3 is provided with a valve port A, a valve port B, a valve port C, a valve port D, a valve port E and a valve port F, the one-dimensional chromatographic column 1 is connected with the valve ports F of the valve port C, and the thermal modulator 4 is connected with the valve ports B and the valve ports E.
The two-dimensional chromatographic column 2 and the detector 5 are connected with a valve port D.
The sample 6 is connected to the valve port a of the six-way switching valve 3.
The valve port A on the six-way switching valve 3 is communicated with the valve port B, the valve port C on the six-way switching valve 3 is communicated with the valve port D, and the valve port E on the six-way switching valve 3 is communicated with the valve port F, in this state, the six-way switching valve 3 is located at the first position, namely the cold trap position.
The valve port B on the six-way switching valve 3 is communicated with the valve port C, the valve port D on the six-way switching valve 3 is communicated with the valve port E, and the valve port F on the six-way switching valve 3 is communicated with the valve port A, in this state, the six-way switching valve 3 is located at the second position, namely the modulator position.
The utility model discloses in, include: the method comprises the following steps that a one-dimensional chromatographic column 1, a thermal modulator 4, a two-dimensional chromatographic column 2 and a six-way switching valve 3 are arranged, when a sample 6 is fed, the six-way switching valve 3 is located at a first position, namely a cold trap position, at the moment, the sample 6 firstly passes through the thermal modulator 4, the thermal modulator 4 firstly carries out a modulation process, the sample 6 is trapped by refrigeration or passes through a cold area of the thermal modulator 4, the thermal modulator 4 releases after a period of time or moves to a hot area to release, the trapped sample 6 is rapidly fed into the one-dimensional chromatographic column 1, after the sample 6 completely enters the one-dimensional chromatographic column 1, the time of several seconds is probably needed, the six-way switching valve 3 is switched to a second position, namely a modulator position, the thermal modulator 4 recovers a normal modulation program and is modulated according to a set modulation period, at the moment, carrier gas firstly enters the one-dimensional chromatographic column 1, then passes through the thermal modulator 4 and then enters the two-dimensional chromatographic column 2 and a detector 5, forming a normal full two-dimensional gas chromatography flow path.
The six-way switching valve 3 can rotate the valve body in a manual, pneumatic or electric mode, so that the communication direction between the ports is changed, and the switching of the flow path is realized.
Secondly, the six-way switching valve 3 can be replaced by a switching valve with eight-way, ten-way or more ports, and the use is more convenient.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (6)
1. The utility model provides a kind and advances a kind cold trap and full two-dimensional chromatogram modulation system, includes six-way diverter valve (3), its characterized in that still includes:
the one-dimensional chromatographic column (1) is connected with two valve ports on the six-way switching valve (3);
the thermal modulator (4) is connected with two valve ports on the six-way switching valve (3);
the detector (5) is connected with one valve port on the six-way switching valve (3);
and a two-dimensional chromatographic column (2) connected between the six-way switching valve (3) and the detector (5).
2. The sample introduction cold trap and full two-dimensional chromatography modulation system according to claim 1, wherein the six-way switching valve (3) is provided with a valve port A, a valve port B, a valve port C, a valve port D, a valve port E and a valve port F, the one-dimensional chromatography column (1) is connected with the valve ports C and F, and the thermal modulator (4) is connected with the valve ports B and E.
3. A sample introduction cold trap and full two-dimensional chromatography modulation system according to claim 2, wherein the two-dimensional chromatography column (2) and the detector (5) are connected with a valve port D.
4. A sample introduction cold trap and full two-dimensional chromatography modulation system according to claim 1, wherein the sample (6) is connected to the valve port a of the six-way switching valve (3).
5. The system according to claim 2, wherein the valve port a of the six-way switching valve (3) is connected to the valve port B, the valve port C of the six-way switching valve (3) is connected to the valve port D, and the valve port E of the six-way switching valve (3) is connected to the valve port F.
6. The system according to claim 2, wherein the valve port B of the six-way switching valve (3) is connected to the valve port C, the valve port D of the six-way switching valve (3) is connected to the valve port E, and the valve port F of the six-way switching valve (3) is connected to the valve port a.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120425684.5U CN214334801U (en) | 2021-02-26 | 2021-02-26 | Sample introduction cold trap and full two-dimensional chromatographic modulation system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120425684.5U CN214334801U (en) | 2021-02-26 | 2021-02-26 | Sample introduction cold trap and full two-dimensional chromatographic modulation system |
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| Publication Number | Publication Date |
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| CN214334801U true CN214334801U (en) | 2021-10-01 |
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| CN202120425684.5U Active CN214334801U (en) | 2021-02-26 | 2021-02-26 | Sample introduction cold trap and full two-dimensional chromatographic modulation system |
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2021
- 2021-02-26 CN CN202120425684.5U patent/CN214334801U/en active Active
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