CN214209117U - Hepatic portal vein catheter - Google Patents
Hepatic portal vein catheter Download PDFInfo
- Publication number
- CN214209117U CN214209117U CN202022245532.5U CN202022245532U CN214209117U CN 214209117 U CN214209117 U CN 214209117U CN 202022245532 U CN202022245532 U CN 202022245532U CN 214209117 U CN214209117 U CN 214209117U
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- sensor
- portal vein
- lead
- groove
- vein catheter
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Abstract
The utility model discloses a hepatic portal vein pipe, include: a pipe body; a guide wire channel, a sensor groove and a lead groove are arranged in the sensor; the sensor is arranged in the sensor groove and used for measuring the pressure of the hepatic portal vein; the lead is arranged in the lead groove of the tube body and used for electrically connecting the sensor with external equipment of the tube body; and the coating is arranged on the outer surface of the wall surface of the pipe body and the sensing outer surface of the sensor and is used for isolating the direct contact between the catheter and external blood. The utility model discloses a portal vein pipe integrated pressure microsensor and medicine/electro photoluminescence targeted therapy microchannel simultaneously can implant for a long time or carry out portal vein pressure monitoring and targeted therapy with short-term intervention mode, and the direct integrated encapsulation of sensor is at body head, can direct measurement portal vein pressure, and it is fast, the accuracy is high to measure the feedback response, and pipe size is little simultaneously, compact structure, percutaneous puncture wound are less.
Description
Technical Field
The utility model belongs to the field of medical equipment, concretely relates to hepatic portal vein pipe.
Background
Portal hypertension is a group of symptoms caused by persistent elevation of portal pressure, typical of chronic conditions. Portal vein pressure increases when portal vein blood fails to flow back through the liver into the inferior vena cava. Most are caused by cirrhosis, and a few are secondary to obstruction of the portal trunk or hepatic veins and other factors of unknown cause. According to statistics, more than 2000 million liver cirrhosis patients exist in the world at present, more than 700 million liver cirrhosis patients exist in China, and the number of patients is increased continuously.
The pressure gradient of the hepatic portal vein is normally 3-5mmHg, the decompensation rate of the liver increases by 11% for every 1mmHg increase, varicose veins are considered to form when the pressure gradient exceeds 10mmHg, the cirrhosis is considered to be abnormal, when the pressure gradient exceeds 12mmHg, the incidence rate of bleeding caused by esophageal varicose rupture reaches 30%, and the fatality rate reaches 20% in 30 days. The abdominal wall and esophageal vein dilatation, splenomegaly, splenic hyperfunction, liver function decompensation, ascites and the like appear in the early stage, the vein dilatation at the connection part of the esophagus and the stomach appears in the severe stage, and once the vein dilatation is broken, serious acute upper gastrointestinal hemorrhage can be caused to endanger life.
Therefore, for portal hypertension patients, in order to accurately predict the sudden increase of portal pressure and even bleeding of the portal vein, the portal blood pressure needs to be monitored regularly for follow-up evaluation, which is an important reference for follow-up treatment. Imaging (color ultrasound, CT, magnetic resonance) radiography is a common method for clinical preliminary diagnosis of portal hypertension. To further confirm the condition, portal hypertension is generally measured clinically by interventional puncture. Under the assistance of images, a catheter is placed through the right femoral vein, enters the lower cavity vein, is inserted into the right hepatic vein through the second portal, is injected with contrast medium for positioning, measures the free hepatic vein pressure (the pressure is transmitted to an external catheter tail end pressure sensor through physiological saline filled in the catheter), and then extends to the hepatic vein tail end to measure the hepatic vein embedded pressure, and the pressure difference between the two is the hepatic vein pressure difference. The method can also be used for measuring the hepatic vein embedded pressure by inserting the catheter into the hepatic vein from the internal jugular vein, injecting water into the balloon to expand and block the hepatic vein backflow, and then pumping out the water in the balloon to recover the hepatic vein backflow to measure the hepatic vein pressure. However, the puncture operation has a high risk and is not beneficial to follow-up after the operation, and in addition, the blood pressure is measured indirectly through the pressure conducted by the physiological saline filled in the catheter, so that the pressure loss exists, the result is inaccurate, and the direct measurement is more prone to be realized clinically and the pressure change condition can be kept to be tracked in real time.
SUMMERY OF THE UTILITY MODEL
The present invention is directed to solve at least some of the above problems in the related art and provides a portal vein duct for the purpose.
In order to achieve the above object, the present invention provides a hepatic portal vein catheter comprising:
the tube body is internally provided with a guide wire channel, a sensor groove and a lead groove;
the sensor is arranged in the groove of the tube body sensor and is used for measuring the pressure of the hepatic portal vein in real time;
the lead is arranged in the lead groove of the tube body and used for electrically connecting the sensor with external equipment of the tube body;
the coating is arranged on the outer surface of the wall surface of the pipe body and the sensing outer surface of the sensor and used for isolating the direct contact between the catheter and external blood and avoiding the biological blood pollution and coagulation on the wall surface of the catheter.
In addition, according to the utility model discloses above-mentioned hepatic portal vein pipe can also have following additional technical characterstic:
an actuator channel is arranged in the pipe body;
the guide wire channel, the sensor groove, the lead groove, the actuator channel and the tube body are integrally formed in the tube body in a micro-machining mode, and the integral micro-machining forming process can select any one of injection molding, extrusion, precision machining and 3D printing.
The guide wire channel is used for placing an interventional operation guide wire, the guide wire channel is not communicated with the sensor groove along the horizontal direction of the catheter, and a certain distance gap is reserved between the guide wire channel and the sensor groove; the sensor groove is used for placing a sensor and keeping a pressure sensing surface of the sensor outward, and the sensor is fixed in the sensor groove through packaging glue; the lead groove is communicated with the sensor groove and is used as a transition connecting channel of the lead and the sensor; the lead is also fixed in the lead groove through packaging glue; the sensor groove and the lead groove are filled with the packaging glue, and the filling process of the packaging glue can select any one of dispensing, spraying, pouring and plastic packaging. The packaging adhesive can be made of biocompatible materials such as resin and silica gel.
The tube body is provided with a pore canal communicated with the actuator channel and used for releasing the medicine through the actuator channel or penetrating through the stimulating electrode to treat the hepatic portal vein abnormality in a targeted manner.
The lead groove is formed in the outer wall surface of the tube body, and the depth of the lead groove is slightly larger than the equivalent outer diameter of the lead.
The sensor can be an MEMS pressure sensor, and can also be an integrated pressure sensor integrated with a micro-control chip.
The lead is any one of biocompatible platinum, gold, stainless steel, nickel, titanium and platinum iridium, can be in the shape of a straight wire, a broken line and a spiral line, can also be a metal film deposited, sputtered and electroplated on the surface of the bottom of the groove of the lead, and can also be a conductive polymer filled in the groove of the lead.
The thickness of the coating is nano or micron, and the coating is made of materials such as parylene, polytetrafluoroethylene and silicon rubber; the material of the pipe body can be selected from nylon, polytetrafluoroethylene, polyether-ether-ketone, polyethylene, polypropylene and the like.
The utility model discloses a portal vein pipe can integrated pressure microsensor and medicine/electro photoluminescence targeted therapy microchannel, can carry out portal vein pressure monitoring and targeted therapy with the intervention mode, and the direct integrated encapsulation of sensor is at body head, can direct measurement portal vein pressure change, and it is fast, the accuracy is high to measure the feedback response, and pipe size is little simultaneously, compact structure, percutaneous puncture wound are less.
Drawings
Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention. Also, like reference numerals are used to refer to like parts throughout the drawings. In the drawings:
FIG. 1 is a longitudinal cross-sectional view of the head of a body of a portal vein catheter in an embodiment of the present invention;
FIG. 2 is a cross-sectional view of the head of a body of a portal vein catheter in an embodiment of the present invention;
fig. 3a and 3b are a longitudinal sectional view and a perspective sectional view of the head of a portal vein catheter with a sensor packaged therein according to an embodiment of the present invention; and
fig. 4a and 4b are a longitudinal cross-sectional view and a perspective cross-sectional view, respectively, of the head of a portal vein catheter encapsulating sensor and actuator channels in another embodiment of the invention.
Detailed Description
Referring to fig. 1 to 3b, an embodiment of the present invention provides a portal vein catheter, which includes a tube 10, a sensor 201, a lead 202, a peripheral wall coating 302 and an end coating 301, wherein the tube 10 is made of a material selected from nylon, teflon, polyetheretherketone, polyethylene, polypropylene, etc.; a guide wire channel 101, a sensor groove 102 and a lead groove 103 which are mutually communicated are arranged in the tube body 10, and the guide wire channel 101 is used for placing an interventional operation guide wire and keeps a certain distance from the sensor groove 102; a sensor 201 is placed in the sensor groove 102 for measuring the pressure of the hepatic portal vein, and a lead 202 is placed in the lead groove 103 for connecting the sensor 201 with a signal acquisition device outside the catheter; a peripheral wall coating 302 is provided on the outer wall surface of the pipe body 10, and an end coating 301 is provided on the outer surface of the pressure-sensitive surface of the sensor 201.
Specifically, in the embodiment of the present invention, the tube body 10 is manufactured by any one of injection molding, extrusion, precision machining, and 3D printing, and the guide wire channel 101, the sensor groove 102, the lead wire groove 103, the actuator channel 104 and the tube body are integrally micro-machined. The material of the pipe body can be selected from nylon, polytetrafluoroethylene, polyether-ether-ketone, polyethylene, polypropylene and the like.
Further, the sensor 201 and the lead 202 are respectively integrated and packaged in the sensor groove 102 and the lead groove 103, any one of dispensing, spraying, pouring and plastic packaging can be selected in the packaging process, and biocompatible materials such as resin and silica gel can be selected in the packaging filling adhesive.
In addition, the pressure sensing surface of the sensor 201 is fixed inside the sensor groove 102 in an outward packaging mode, and the equivalent outer diameter of the lead 202 is not larger than the depth of the lead groove 103.
The peripheral wall coating 302 and the end coating 301 are respectively used as protective films of a pressure sensing surface of the sensor and the outer wall surface of the tube body to isolate the direct contact of the catheter and blood and avoid biological pollution and coagulation of blood, the thickness of the coating is nanometer or micron-sized to reduce the influence on the blood flow pressure sensing of the pressure sensing surface of the sensor 201 to the maximum extent, and the material of the coating can be selected from biocompatible materials such as parylene, polytetrafluoroethylene, biological silica gel and the like.
Further, the peripheral wall coating 302 and the end coating 301 may be prepared by sputtering, deposition, evaporation, or the like.
It is worth mentioning that, in the embodiment of the present invention, the sensor 201 may be a MEMS pressure micro sensor, and may also be an integrated pressure micro sensor of an integrated micro control chip.
In addition, in the embodiment of the present invention, the shape of the lead 202 may be a straight wire, a polygonal line, a spiral line, or a metal thin film deposited, sputtered, or electroplated on the bottom surface of the lead groove 103, and the material of the lead 202 may be any one of biocompatible platinum, gold, stainless steel, nickel, titanium, platinum iridium, or a conductive polymer filling the lead groove 103.
Referring to fig. 4a and 4b, another embodiment of the present invention provides a portal vein catheter, which may further integrate an actuator channel 104, wherein the actuator channel 104 is formed on the tube body 10 and has a hole communicating with the outside of the tube body 10, and the actuator channel 104 may be used as a drug delivery channel for releasing drugs into the portal vein, or may pass through a stimulation electrode to be used as stimulation therapy for portal vein abnormality.
Compared with the prior art, the utility model discloses a portal vein pipe can be integrated pressure microsensor and medicine/electro photoluminescence targeted therapy microchannel simultaneously, can implant for a long time or carry out portal vein pressure monitoring and targeted therapy with short-term intervention mode, and the direct integrated encapsulation of sensor is at body head, can direct measurement portal vein pressure change, and measurement feedback response is fast, accuracy is high, and pipe size is little simultaneously, compact structure, percutaneous puncture wound are less.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention should be covered by the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
1. A portal vein catheter, comprising:
the tube body is internally provided with a guide wire channel, a sensor groove and a lead groove;
the sensor is arranged in the sensor groove of the tube body and used for measuring the pressure of the hepatic portal vein in real time;
the lead is arranged in the lead groove of the tube body and used for electrically connecting the sensor with signal acquisition equipment outside the tube body;
the coating is arranged on the outer surface of the wall surface of the pipe body and the sensing outer surface of the sensor and used for isolating the direct contact between the catheter and external blood and avoiding the blood pollution and coagulation on the wall surface of the catheter.
2. The hepatic portal vein catheter of claim 1, wherein an actuator channel is further disposed within the body.
3. The hepatic portal vein catheter of claim 2, wherein the guide wire channel, sensor groove, lead groove, actuator channel are integrally micro-machined into the body by any one of injection molding, extrusion, precision machining, 3D printing.
4. The hepatic portal vein catheter according to claim 3, wherein the material of the tube body is any one of nylon, polytetrafluoroethylene, polyetheretherketone, polyethylene, polypropylene.
5. The portal vein catheter of claim 1, wherein said sensor and said lead are encapsulated within said sensor recess and said lead recess, respectively.
6. The hepatic portal vein catheter according to claim 5, wherein the filling process of the sensor and the lead packaging adhesive is any one of dispensing, spraying, pouring and plastic packaging.
7. The hepatic portal vein catheter of claim 6, wherein the encapsulating gel is a biocompatible material that is a resin or a silicone gel.
8. The portal vein catheter of claim 1, wherein said lead is any one of biocompatible platinum, gold, stainless steel, nickel, titanium, platinum iridium, or a conductive polymer filled in said lead groove.
9. The portal vein catheter of claim 8, wherein said lead wire is a straight wire, a bent wire or a spiral wire, or a thin metal film deposited, sputtered, plated on the bottom surface of said lead wire groove.
10. The hepatic portal vein catheter of claim 1, wherein the coating is of nano or micro thickness and is of parylene, teflon or silicone rubber material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022245532.5U CN214209117U (en) | 2020-10-09 | 2020-10-09 | Hepatic portal vein catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022245532.5U CN214209117U (en) | 2020-10-09 | 2020-10-09 | Hepatic portal vein catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214209117U true CN214209117U (en) | 2021-09-17 |
Family
ID=77694207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022245532.5U Expired - Fee Related CN214209117U (en) | 2020-10-09 | 2020-10-09 | Hepatic portal vein catheter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214209117U (en) |
-
2020
- 2020-10-09 CN CN202022245532.5U patent/CN214209117U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210917 |