CN214142314U - Nucleic acid extraction device for POCT - Google Patents

Abstract

The utility model discloses a magnetic bead method nucleic acid extraction element for POCT, concretely relates to medical equipment technical field, the heat preservation box comprises an insulation box body, the fixed support frame that is equipped with in heat preservation box top, the fixed first test tube, second test tube, third test tube, fourth test tube and the fifth test tube that is equipped with in support frame top, the even interval of first test tube, second test tube, third test tube, fourth test tube and fifth test tube sets up, first test tube and fifth test tube bottom run through support frame and heat preservation box in proper order and extend to inside the heat preservation box. The utility model discloses a board is placed in the extrusion, makes the rack shift up down through the gear and shifts up, and clamp plate extrusion solution makes it get into the solution intracavity through the inlet channel, adsorbs by the magnetic pen, and the third motor drives extraction element and moves on the whole, and the spring resilience resets, drives slide damper and blocks up the intercommunication mouth shutoff, and the solution after the use then flows to the stock solution section of thick bamboo follow-up processing of being convenient for from the L venturi tube, and overall structure easy operation is convenient.

Description

Nucleic acid extraction device for POCT

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to a nucleic acid extraction element for POCT.

Background

The common methods for extracting nucleic acid include a magnetic bead method and a concentrated salt method, wherein the magnetic bead method uses a nanotechnology to improve and modify the surface of superparamagnetic nanoparticles to prepare superparamagnetic silica nanobeads, the nanobeads can be specifically identified and efficiently combined with nucleic acid molecules on a microscopic interface, and DNA and RNA in samples such as blood, animal tissues, food, pathogenic microorganisms and the like can be separated under the action of guanidine hydrochloride, guanidine isothiocyanate and the like and an external magnetic field by utilizing the superparamagnetism of silica nanobeads, so that the superparamagnetic silica nanobeads can be applied to various fields such as clinical disease diagnosis, blood transfusion safety, forensic medicine identification, environmental microorganism detection, food safety detection, molecular biology research and the like.

The prior art has the following defects: the nucleic acid extraction needs a user to add a reagent, so the operation is not convenient enough and the error is easy to occur.

SUMMERY OF THE UTILITY MODEL

Therefore, the utility model provides a nucleic acid extraction device for POCT, which is characterized in that an upper rack on a placing plate is moved downwards to be meshed with a gear by extruding the placing plate, the spring is compressed by the cross rod, the gear drives the lower rack to move upwards, the lower rack moves upwards to drive the pressing plate to move upwards, the pressing plate extrudes the solution in the solution tank to enable the solution to enter the solution cavity through the water outlet, the water inlet pipeline and the communicating port, the sample is contacted with the solution and simultaneously is stirred by the magnetic pen which is driven to rotate by the second motor, so that the adsorption effect is better, after the sample is adsorbed, the extraction device is driven to move upwards integrally by the third motor, the spring is not pressed to rebound and reset, and the placing plate and the sliding baffle plate on the placing plate are driven to seal the communicating port, the used solution flows into the liquid storage cylinder from the L-shaped pipe, so that the subsequent treatment is convenient, the operation of the whole structure is simple and convenient, and the reagent does not need to be added when the nucleic acid is extracted every time.

In order to achieve the above object, the present invention provides the following technical solutions: a nucleic acid extraction device for POCT comprises an insulation can, wherein a support frame is fixedly arranged at the top of the insulation can, a first test tube, a second test tube, a third test tube, a fourth test tube and a fifth test tube are fixedly arranged at the top of the support frame, the first test tube, the second test tube, the third test tube, the fourth test tube and the fifth test tube are uniformly arranged at intervals, the bottom ends of the first test tube and the fifth test tube sequentially penetrate through the support frame and the insulation can and extend into the insulation can, the bottom end of the second test tube penetrates through the support frame and is fixedly connected with the top of the insulation can, the bottom ends of the third test tube and the fourth test tube both penetrate through the support frame and extend to the lower part of the support frame, solution boxes are fixedly arranged at the bottom ends of the first test tube, the third test tube, the fourth test tube and the fifth test tube, the solution boxes are fixedly connected with the bottom of an inner cavity of the insulation can, and the solution boxes on the third test tube and the fourth test tube are fixedly connected with the top of the insulation can, the solution chamber has all been seted up to first test tube, third test tube, fourth test tube and fifth test tube inside, the solution intracavity portion is equipped with places the board, the spout has all been seted up to solution chamber both sides inner wall, the inside slide damper that is equipped with of spout, the one side intercommunication that slide damper kept away from and place the board has the intercommunication mouth, the fixed intercommunication in intercommunication mouth bottom has water inlet channel, first test tube, third test tube, fourth test tube and fifth test tube are run through respectively to the water inlet channel bottom, it is equipped with the gear to place the board below, both ends all are connected with solution intracavity wall through the bearing around the gear, the gear both sides mesh respectively has upper rack and lower rack, upper rack and place board fixed connection, the inside clamp plate that is equipped with of solution tank, the fixed connecting rod that is equipped with in clamp plate top, the connecting rod runs through the solution tank and extends to the solution tank outside, the connecting rod top runs through first test tube respectively, Third test tube, fourth test tube and fifth test tube, the lower rack fixed connection of connecting rod and solution intracavity, solution roof portion runs through and has seted up two outlets, and two outlets are linked together with two inlet channel on first test tube, third test tube, fourth test tube and the fifth test tube respectively, the spacing groove has all been seted up to the both sides inner wall around the solution chamber, the fixed spring that is equipped with in spacing inslot portion, the fixed horizontal pole that is equipped with in spring top, horizontal pole and last rack fixed connection, the support frame top is equipped with adjusting device, adjusting device and insulation can fixed connection, the fixed extraction element that is equipped with in adjusting device bottom.

Furthermore, the adjusting device comprises two fixing plates, the fixing plates are fixedly connected with the heat preservation box, a linear guide rail is fixedly arranged between the two fixing plates, a first motor is arranged above the heat preservation box, the output end of the first motor penetrates through one of the fixing plates and is fixedly connected with a screw rod in the linear guide rail, and a sliding block on the linear guide rail is fixedly connected with the extraction device.

Further, the extraction device comprises a mounting plate, the mounting plate is fixedly connected with a slider on the linear guide rail, two C-shaped plates are fixedly arranged at the bottom of the mounting plate, a threaded rod and a guide rod are respectively arranged between the inner walls of the two ends of the two C-shaped plates, the two ends of the threaded rod are connected with one of the C-shaped plates through a bearing, the two ends of the guide rod are fixedly connected with the C-shaped plate, a movable plate is movably sleeved on the outer walls of the threaded rod and the guide rod, the threaded rod is in threaded connection with the movable plate, the guide rod is in sliding connection with the movable plate, a second motor is fixedly arranged at the bottom of the movable plate, a straight plate is fixedly arranged at the bottom of the second motor, a magnetic pen is fixedly arranged at the bottom of the straight plate, the magnetic pen is connected with the straight plate through a bearing, push rods are arranged on the two sides of the magnetic pen, the push rods are fixedly connected with the straight plate, a third motor is fixedly arranged at the top of the mounting plate, the output end of the third motor penetrates through the mounting plate and is fixedly connected with the threaded rod.

Further, the first test tube, the third test tube, the fourth test tube and the fifth test tube are fixedly communicated with the front side and the rear side respectively to form an L-shaped tube, the L-shaped tube is communicated with the solution cavity, a liquid storage barrel is arranged below the L-shaped tube, the liquid storage barrel is arranged on the first test tube, the heat insulation box top and the third test tube are arranged on the front side and the rear side of the fifth test tube, and the solution box tops are arranged on the front side and the rear side of the fourth test tube.

Furthermore, both ends are fixed intercommunication respectively around the solution tank have feed liquor pipe and drain pipe, set up around feed liquor pipe and the drain pipe, feed liquor pipe and drain pipe on first test tube and the fifth test tube run through the insulation can respectively around with the rear side and extend to the insulation can outside.

Furthermore, a water injection port is formed in one side of the surface of the top of the heat insulation box.

Further, the lysate has been placed to the inside of the solution tank on the first test tube, the magnetic bead has been placed to the inside of second test tube, the rinsing liquid has been placed to the solution tank inside on third test tube and the fourth test tube, the eluant has been placed to the solution tank inside on the fifth test tube.

Further, the L-shaped pipe is arranged above the communication port.

Compared with the prior art, the utility model discloses following beneficial effect has:

the utility model discloses a board is placed in the extrusion, the messenger places last rack on the board and moves down with gear engagement, and through horizontal pole compression spring, the rack shifts up under the gear drive, the rack shifts up down and drives the clamp plate and shifts up, the solution in the clamp plate extrusion solution tank makes it through the outlet, inlet channel and intercommunication mouth get into the solution intracavity, the sample stirs by the rotatory magnetic pen of second motor drive simultaneously with the solution contact is inside, make adsorption effect better, it shifts up wholly to drive extraction element through the third motor after adsorbing, the spring does not receive the pressure resilience to reset, the drive is placed the board and the sliding baffle on it and is blocked up the intercommunication mouth, and the solution after the use then flows to the stock solution section of thick bamboo follow-up processing of being convenient for from the L venturi tube, overall structure easy operation is convenient, do not need all oneself when extracting nucleic acid at every turn add reagent.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It should be apparent that the drawings in the following description are merely exemplary, and that other embodiments can be derived from the drawings provided by those of ordinary skill in the art without inventive effort.

The structure, ratio, size and the like shown in the present specification are only used for matching with the content disclosed in the specification, so as to be known and read by people familiar with the technology, and are not used for limiting the limit conditions which can be implemented by the present invention, so that the present invention has no technical essential significance, and any structure modification, ratio relationship change or size adjustment should still fall within the scope which can be covered by the technical content disclosed by the present invention without affecting the efficacy and the achievable purpose of the present invention.

Fig. 1 is a cross-sectional view of the overall structure provided by the present invention;

FIG. 2 is a side sectional view of the linear guide rail and the magnetic pen according to the present invention;

fig. 3 is a top view of the first test tube, the second test tube, the third test tube, the fourth test tube and the fifth test tube provided by the present invention;

FIG. 4 is a sectional view of the incubator of the present invention;

FIG. 5 is an enlarged view of the portion A in FIG. 1 according to the present invention;

fig. 6 is an enlarged view of a portion B in fig. 1 according to the present invention.

In the figure: 1 insulation can, 2 support frames, 3 first test tubes, 4 second test tubes, 5 third test tubes, 6 fourth test tubes, 7 fifth test tubes, 8 solution boxes, 9 solution chambers, 10 placing plates, 11 sliding baffle plates, 12 communication ports, 13 water inlet channels, 14 gears, 15 upper racks, 16 lower racks, 17 pressing plates, 18 connecting rods, 19 water outlets, 20 springs, 21 cross rods, 22 fixing plates, 23 linear guide rails, 24 first motors, 25 screw rods, 26 sliding blocks, 27 mounting plates, 28C-shaped plates, 29 threaded rods, 30 guide rods, 31 movable plates, 32 second motors, 33 straight plates, 34 magnetic force pens, 35 push rods, 36 third motors, 37L-shaped tubes, 38 liquid storage barrels, 39 liquid inlet tubes, 40 liquid outlet tubes and 41 water injection ports.

Detailed Description

The present invention is described in terms of specific embodiments, and other advantages and benefits of the present invention will become apparent to those skilled in the art from the following disclosure. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to the attached drawings 1-6 of the specification, the nucleic acid extraction device for POCT of the embodiment comprises an insulation can 1, a support frame 2 is fixedly arranged at the top of the insulation can 1, a first test tube 3, a second test tube 4, a third test tube 5, a fourth test tube 6 and a fifth test tube 7 are fixedly arranged at the top of the support frame 2, the first test tube 3, the second test tube 4, the third test tube 5, the fourth test tube 6 and the fifth test tube 7 are uniformly arranged at intervals, the bottom ends of the first test tube 3 and the fifth test tube 7 sequentially penetrate through the support frame 2 and the insulation can 1 and extend into the insulation can 1, the bottom end of the second test tube 4 penetrates through the support frame 2 and is fixedly connected with the top of the insulation can 1, the bottom ends of the third test tube 5 and the fourth test tube 6 both penetrate through the support frame 2 and extend to the lower part of the support frame 2, solution boxes 8 are fixedly arranged at the bottom ends of the first test tube 3, the third test tube 5, the fourth test tube 6 and the fifth test tube 7, the solution box 8 on the first test tube 3 and the fifth test tube 7 is fixedly connected with the bottom of the inner cavity of the insulation can 1, the solution box 8 on the third test tube 5 and the fourth test tube 6 is fixedly connected with the top of the insulation can 1, the solution cavities 9 are respectively arranged inside the first test tube 3, the third test tube 5, the fourth test tube 6 and the fifth test tube 7, a placing plate 10 is arranged inside the solution cavity 9, sliding grooves are respectively arranged on the inner walls of the two sides of the solution cavity 9, sliding baffles 11 are arranged inside the sliding grooves, a communicating port 12 is communicated with one side of each sliding baffle 11 far away from the placing plate 10, a water inlet channel 13 is fixedly communicated with the bottom of each communicating port 12, the bottom end of each water inlet channel 13 respectively penetrates through the first test tube 3, the third test tube 5, the fourth test tube 6 and the fifth test tube 7, a gear 14 is arranged below the placing plate 10, and the front end and the rear end of each gear 14 are connected with the inner wall of the solution cavity 9 through a bearing, an upper rack 15 and a lower rack 16 are respectively meshed with two sides of the gear 14, the upper rack 15 is fixedly connected with the placing plate 10, a pressing plate 17 is arranged inside the solution tank 8, a connecting rod 18 is fixedly arranged at the top of the pressing plate 17, the connecting rod 18 penetrates through the solution tank 8 and extends to the outside of the solution tank 8, the top end of the connecting rod 18 penetrates through the first test tube 3, the third test tube 5, the fourth test tube 6 and the fifth test tube 7 respectively, the connecting rod 18 is fixedly connected with the lower rack 16 in the solution chamber 9, two water outlets 19 are formed at the top of the solution tank 8 in a penetrating manner, the two water outlets 19 are respectively communicated with the two water inlet channels 13 on the first test tube 3, the third test tube 5, the fourth test tube 6 and the fifth test tube 7, limiting grooves are formed in the inner walls of the front side and the rear side of the solution chamber 9, springs 20 are fixedly arranged inside the limiting grooves, cross rods 21 are fixedly arranged at the top ends of the springs 20, the cross rod 21 is fixedly connected with the upper rack 15, an adjusting device is arranged above the support frame 2 and fixedly connected with the heat preservation box 1, and an extracting device is fixedly arranged at the bottom of the adjusting device.

Further, the adjusting device comprises two fixing plates 22, the fixing plates 22 are fixedly connected with the heat insulation box 1, a linear guide rail 23 is fixedly arranged between the two fixing plates 22, a first motor 24 is arranged above the heat insulation box 1, the output end of the first motor 24 penetrates through one of the fixing plates 22 and is fixedly connected with a screw rod 25 in the linear guide rail 23, and a sliding block 26 on the linear guide rail 23 is fixedly connected with the extracting device, so that the left and right movement and adjustment of the corresponding test tube are facilitated.

Further, the extraction device comprises a mounting plate 27, the mounting plate 27 is fixedly connected with a slider 26 on the linear guide rail 23, two C-shaped plates 28 are fixedly arranged at the bottom of the mounting plate 27, a threaded rod 29 and a guide rod 30 are respectively arranged between inner walls of two ends of the two C-shaped plates 28, two ends of the threaded rod 29 are connected with one of the C-shaped plates 28 through bearings, two ends of the guide rod 30 are fixedly connected with the C-shaped plates 28, the outer walls of the threaded rod 29 and the guide rod 30 are movably sleeved with the same movable plate 31, the threaded rod 29 is in threaded connection with the movable plate 31, the guide rod 30 is in sliding connection with the movable plate 31, a second motor 32 is fixedly arranged at the bottom of the movable plate 31, a straight plate 33 is fixedly arranged at the bottom of the second motor 32, a magnetic pen 34 is fixedly arranged at the bottom of the straight plate 33, the magnetic pen 34 is connected with the straight plate 33 through a bearing, and push rods 35 are arranged on two sides of the magnetic pen 34, the push rod 35 and the straight plate 33 are fixedly connected, the third motor 36 is fixedly arranged at the top of the mounting plate 27, the output end of the third motor 36 penetrates through the mounting plate 27 and the threaded rod 29 and is driven by an electric element, and the operation of a user is facilitated, so that time and labor are saved.

Further, the intercommunication that all is fixed to both sides around first test tube 3, third test tube 5, fourth test tube 6 and the fifth test tube 7 has L venturi tube 37, L venturi tube 37 is linked together with solution chamber 9, L venturi tube 37 below is equipped with stock solution bucket 38, stock solution bucket 38 sets up respectively in first test tube 3, 1 top and the third test tube 5 of insulation can of both sides around the fifth test tube 7, the 8 tops of solution tank of both sides around the fourth test tube 6 are convenient for discharge the solution of spent, avoid mixing with subsequent solution and influence the extraction effect.

Further, both ends are fixed respectively around solution tank 8 and are communicated with feed liquor pipe 39 and drain pipe 40, feed liquor pipe 39 and drain pipe 40 set up back and forth, feed liquor pipe 39 and drain pipe 40 on first test tube 3 and the fifth test tube 7 run through respectively around insulation can 1 with the rear side and extend to insulation can 1 outside, and convenience of customers operates, is convenient for change the solution in solution tank 8.

Furthermore, a water injection port 41 is formed in one side of the top surface of the heat insulation box 1, so that the operation of a user is facilitated.

Further, the lysate has been placed to solution tank 8 inside on the first test tube 3, the magnetic bead has been placed to second test tube 4 inside, the rinsing liquid has been placed to solution tank 8 inside on third test tube 5 and the fourth test tube 6, the eluant has been placed to solution tank 8 inside on the fifth test tube 7, is convenient for carry out the extraction of nucleic acid.

Further, the L-shaped pipe 37 is provided above the communication port 12, and both are not on a horizontal line, so that water does not flow out of the L-shaped pipe 37 when entering the communication port 12, and does not flow out of the communication port 12 when flowing out.

The implementation scenario is specifically as follows:

when the utility model is used, hot water is poured into the heat preservation box 1 by a worker from a water filling port 41, then a detection sample is added into a first test tube 3, then a starting device starts working, a first motor 24 on an adjusting device drives a magnetic pen 34 on an extracting device to move to the position above a second test tube 4 through a linear guide rail 23, a second motor 32 and a third motor 36 in the extracting device operate to drive a threaded rod 29 to rotate so as to enable a movable plate 31 limited by a guide rod 30 to move downwards, the magnetic pen 34 on the movable plate 31 gradually contacts with a magnetic bead in the second test tube 4 and adsorbs the magnetic bead, then the third motor 36 rotates reversely to drive the whole body to reset, the magnetic pen 34 is moved to the position above the first test tube 3 through the linear guide rail 23 on the adjusting device, the third motor 36 and the second motor 32 are started simultaneously, the second motor 32 drives the magnetic pen 34 to rotate, the third motor 36 enables the whole body to move downwards through the thread matching of the threaded rod 29 and the movable plate 31, when the sample is moved into the first test tube 3, the push rod 35 firstly contacts with the placing plate 10 and extrudes the placing plate to enable the placing plate 10 and the sliding baffle 11 in the sliding chute to move downwards to expose the communication port 12, when the upper rack 15 on the placing plate 10 moves downwards to be meshed with the gear 14 and the spring 20 is compressed through the cross rod 21, the gear 14 drives the lower rack 16 to move upwards, the lower rack 16 moves upwards to drive the pressing plate 17 to move upwards, the pressing plate 17 extrudes the lysate in the solution box 8 to enable the lysate to enter the solution cavity 9 through the water outlet 19, the water inlet pipeline and the communication port 12, the sample is contacted with the lysate and simultaneously is better adsorbed by the magnetic pen 34 driven to rotate by the second motor 32, so that the adsorption effect is better, after the sample is adsorbed, the extracting device is driven to move upwards by the third motor 36, the spring 20 is not pressed and rebounded to reset, and drives the placing plate 10 and the sliding baffle 11 on the placing plate to block the communication port 12, and the solution after using then flows to the stock solution section of thick bamboo follow-up processing of being convenient for from L venturi tube 37 in, later remove to third test tube 5, fourth test tube 6 and fifth test tube 7 in proper order by adjusting device and extraction element cooperation again, the impurity that the magnetic bead carried is washd to the rinsing liquid in third test tube 5 and the fourth test tube 6, the eluant in the fifth test tube 7 elutes nucleic acid to flow to the stock solution section of thick bamboo through L venturi tube 37 simultaneously and be convenient for follow-up processing to use.

Although the invention has been described in detail with respect to the general description and the specific embodiments, it will be apparent to those skilled in the art that modifications and improvements can be made based on the invention. Therefore, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims (8)

1. A nucleic acid extraction device for POCT, comprising a heat-insulating box (1), characterized in that: insulation can (1) top is fixed and is equipped with support frame (2), support frame (2) top is fixed and is equipped with first test tube (3), second test tube (4), third test tube (5), fourth test tube (6) and fifth test tube (7), first test tube (3), second test tube (4), third test tube (5), fourth test tube (6) and fifth test tube (7) even interval set up, support frame (2) and insulation can (1) are run through in proper order and extend to inside insulation can (1) first test tube (3) and fifth test tube (7) bottom, support frame (2) and insulation can (1) top fixed connection are run through to second test tube (4) bottom, support frame (2) and extend to support frame (2) below all run through to third test tube (5) and fourth test tube (6) bottom, first test tube (3), third test tube (5), The bottom ends of a fourth test tube (6) and a fifth test tube (7) are respectively fixedly provided with a solution box (8), the solution boxes (8) on the first test tube (3) and the fifth test tube (7) are fixedly connected with the bottom of an inner cavity of the heat insulation box (1), the solution boxes (8) on the third test tube (5) and the fourth test tube (6) are fixedly connected with the top of the heat insulation box (1), the inner parts of the first test tube (3), the third test tube (5), the fourth test tube (6) and the fifth test tube (7) are respectively provided with a solution cavity (9), a placing plate (10) is arranged inside the solution cavity (9), the inner walls at two sides of the solution cavity (9) are respectively provided with a sliding chute, a sliding baffle (11) is arranged inside the sliding chute, one side of the sliding baffle (11) far away from the placing plate (10) is communicated with a communication port (12), and the bottom of the communication port (12) is fixedly communicated with a water inlet channel (13), the bottom end of the water inlet channel (13) penetrates through the first test tube (3), the third test tube (5), the fourth test tube (6) and the fifth test tube (7) respectively, a gear (14) is arranged below the placing plate (10), the front end and the rear end of the gear (14) are connected with the inner wall of the solution chamber (9) through bearings, an upper rack (15) and a lower rack (16) are meshed on two sides of the gear (14) respectively, the upper rack (15) is fixedly connected with the placing plate (10), a pressing plate (17) is arranged inside the solution chamber (8), a connecting rod (18) is fixedly arranged at the top of the pressing plate (17), the connecting rod (18) penetrates through the solution chamber (8) and extends to the outside of the solution chamber (8), the top end of the connecting rod (18) penetrates through the first test tube (3), the third test tube (5), the fourth test tube (6) and the fifth test tube (7) respectively, and the connecting rod (18) is fixedly connected with the lower rack (16) in the solution chamber (9), the improved test tube comprises a solution box (8), wherein the top of the solution box (8) is provided with two water outlets (19) in a penetrating manner, the two water outlets (19) are communicated with two water inlet channels (13) on a first test tube (3), a third test tube (5), a fourth test tube (6) and a fifth test tube (7) respectively, the inner walls of the front side and the rear side of a solution cavity (9) are provided with limiting grooves, springs (20) are fixedly arranged in the limiting grooves, the top ends of the springs (20) are fixedly provided with transverse rods (21), the transverse rods (21) are fixedly connected with an upper rack (15), an adjusting device is arranged above a support frame (2), the adjusting device is fixedly connected with an insulation box (1), and an extraction device is fixedly arranged at the bottom of the adjusting device.

2. The nucleic acid extraction device for POCT according to claim 1, wherein: the adjusting device comprises two fixing plates (22), the fixing plates (22) are fixedly connected with the heat preservation box (1), a linear guide rail (23) is fixedly arranged between the two fixing plates (22), a first motor (24) is arranged above the heat preservation box (1), the output end of the first motor (24) penetrates through one of the fixing plates (22) and a screw rod (25) in the linear guide rail (23) to be fixedly connected, and a sliding block (26) on the linear guide rail (23) is fixedly connected with the extracting device.

3. The nucleic acid extraction device for POCT according to claim 2, wherein: the extraction element includes mounting panel (27), slider (26) fixed connection on mounting panel (27) and linear guide (23), mounting panel (27) bottom is fixed and is equipped with two C shaped plate (28), is equipped with threaded rod (29) and guide arm (30) between the both ends inner wall of two C shaped plate (28) respectively, threaded rod (29) both ends are passed through the bearing and are connected with one of them C shaped plate (28), guide arm (30) both ends and C shaped plate (28) fixed connection, threaded rod (29) and guide arm (30) outer wall movable sleeve are equipped with same fly leaf (31), threaded rod (29) and fly leaf (31) threaded connection, guide arm (30) and fly leaf (31) sliding connection, fly leaf (31) bottom is fixed and is equipped with second motor (32), second motor (32) bottom is fixed and is equipped with straight board (33), straight board (33) bottom is fixed and is equipped with magnetic pen (34), magnetic pen (34) are connected with straight board (33) through the bearing, magnetic pen (34) both sides all are equipped with push rod (35), push rod (35) and straight board (33) fixed connection, mounting panel (27) top is fixed and is equipped with third motor (36), third motor (36) output runs through mounting panel (27) and threaded rod (29) fixed connection.

4. The nucleic acid extraction device for POCT according to claim 1, wherein: first test tube (3), third test tube (5), fourth test tube (6) and fifth test tube (7) around both sides all fixed intercommunication have L venturi tube (37), L venturi tube (37) are linked together with solution chamber (9), L venturi tube (37) below is equipped with stock solution bucket (38), stock solution bucket (38) set up respectively in first test tube (3), insulation can (1) top and third test tube (5) of both sides around fifth test tube (7), solution tank (8) top of both sides around fourth test tube (6).

5. The nucleic acid extraction device for POCT according to claim 1, wherein: solution tank (8) front and back both ends are fixed intercommunication respectively have feed liquor pipe (39) and drain pipe (40), set up around feed liquor pipe (39) and drain pipe (40), feed liquor pipe (39) and drain pipe (40) on first test tube (3) and fifth test tube (7) run through insulation can (1) front side and rear side respectively and extend to insulation can (1) outside.

6. The nucleic acid extraction device for POCT according to claim 1, wherein: one side of the surface of the top of the heat preservation box (1) is provided with a water injection port (41).

7. The nucleic acid extraction device for POCT according to claim 1, wherein: lysate has been placed to solution tank (8) inside on first test tube (3), the magnetic bead has been placed to second test tube (4) inside, the rinsing liquid has been placed to solution tank (8) inside on third test tube (5) and fourth test tube (6), the eluant has been placed to solution tank (8) inside on fifth test tube (7).

8. The nucleic acid extraction device for POCT according to claim 4, wherein: the L-shaped pipe (37) is disposed above the communication port (12).

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