CN214058286U - A quality control transports box for PCR detect reagent - Google Patents
A quality control transports box for PCR detect reagent Download PDFInfo
- Publication number
- CN214058286U CN214058286U CN202021876675.XU CN202021876675U CN214058286U CN 214058286 U CN214058286 U CN 214058286U CN 202021876675 U CN202021876675 U CN 202021876675U CN 214058286 U CN214058286 U CN 214058286U
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 54
- 230000032258 transport Effects 0.000 title description 6
- 238000003908 quality control method Methods 0.000 title description 3
- 238000009434 installation Methods 0.000 claims abstract description 30
- 238000001514 detection method Methods 0.000 claims description 11
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 10
- 229910052802 copper Inorganic materials 0.000 claims description 10
- 239000010949 copper Substances 0.000 claims description 10
- 238000002347 injection Methods 0.000 claims description 10
- 239000007924 injection Substances 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 8
- 230000002427 irreversible effect Effects 0.000 claims description 6
- 238000009529 body temperature measurement Methods 0.000 claims description 4
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- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 1
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Abstract
The utility model discloses a box is transported in article accuse for PCR detect reagent, comprises a box bod, above-mentioned box body upper portion sets up the opening, it has the installation department of placing the reagent to be equipped with the distribution in the above-mentioned box body, be equipped with the anti-shake sponge in the above-mentioned installation department, above-mentioned box body bottom is equipped with the thermostatic chamber, inject temperature-controlled medium in the above-mentioned thermostatic chamber, above-mentioned box body lateral wall is equipped with the socket, insert the backup pad in the above-mentioned socket, above-mentioned backup pad is located the installation department top, be equipped with the buffer block in the above-mentioned installation department, the reagent of contradicting of above-mentioned buffer block lower extreme, buffer block upper end conflict backup pad lower extreme, above-mentioned installation department one side is equipped with the temperature cell, the temperature cell has been placed in the above-mentioned temperature cell, a rock for improving appearing in the reagent transportation, current transport box, if the box temperature surpasses the scope of preserving, be difficult for being perceived the problem.
Description
Technical Field
The utility model belongs to PCR detects the apparatus, concretely relates to article accuse transport box for PCR detect reagent.
Background
The basic principle of PCR technology is similar to the natural replication process of DNA, and its specificity depends on oligonucleotide primers complementary to both ends of the target sequence. Semi-preserved replication of DNA is an important route for biological evolution and passage. Typically an enzymatic synthesis reaction that specifically amplifies a DNA segment between two copies of a known sequence in the presence of a template, primers, dntps, and a heat-dependent DNA polymerase.
In the practical application process, bacteria are separated and identified by sampling samples, and different virus strains are determined. The application of the detection technology needs to optimize the process as much as possible, so that a plurality of detection reagents are prepared according to different virus types, and the detection reagents are usually reaction liquid, positive control reagents, negative control reagents and the like.
Because different reagents have different preservation conditions, part of the reagents have preservation temperature requirements, and the preservation temperature of the reagents is usually zero to thirty ℃, so that the accuracy of the detection result is ensured; the existing transport box is not easy to be perceived if the temperature in the box exceeds the preservation range, so that the risk of reagent accuracy deviation occurs, meanwhile, in the reagent transport process, the shaking is reduced, unnecessary risks caused by reagent damage are avoided, and therefore, how to transport different reagents according to different quality guarantee requirements is worth researching.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a box is transported in accuse for PCR detect reagent for improve rocking that appears in the reagent transportation, current transportation box if the box internal temperature surpasses the scope of preserving, is difficult for being perceived the problem.
In order to solve the technical problem, the utility model adopts the following technical scheme:
the utility model provides a box is transported in article accuse for PCR detect reagent, comprises a box bod, above-mentioned box body upper portion sets up the opening, it has the installation department of placing the reagent to distribute to be equipped with in the above-mentioned box body, be equipped with the anti-shake sponge in the above-mentioned installation department, above-mentioned box body bottom is equipped with the thermostatic chamber, inject temperature-controlled medium in the above-mentioned thermostatic chamber, above-mentioned box body lateral wall is equipped with the socket, insert the backup pad in the above-mentioned socket, above-mentioned backup pad is located the installation department top, be equipped with the buffer block in the above-mentioned installation department, the reagent of contradicting of above-mentioned buffer block lower extreme, buffer block upper end conflict backup pad lower extreme, above-mentioned installation department one side is equipped with the temperature measurement groove, the temperature measurement unit has been placed in the above-mentioned temperature measurement groove.
Preferably, a box cover is arranged in the opening, the lower end of the box cover is abutted against the upper end of the supporting plate, the opening is gradually reduced from the upper end to the lower end, and the box cover is matched with the opening.
Preferably, the side wall of the box body is provided with a limiting groove corresponding to the socket, the front end of the support plate is provided with a bulge matched with the limiting groove, and the support plate is limited by inserting the bulge into the limiting groove.
Preferably, the temperature measuring unit comprises a copper bar, and the surface of the copper bar is covered with irreversible thermosensitive color-changing paint.
Preferably, more than two shunting shifting pieces are arranged in the thermostatic chamber, and a passage is reserved between the two shunting shifting pieces.
The further technical scheme is that an injection opening is formed in the side wall of the constant-temperature cavity, a sealing plug is mounted on the injection opening, and the sealing plug is matched with the injection opening.
Compared with the prior art, the beneficial effects and advantages of the utility model reside in:
the utility model has the advantages that the installation part is used for accommodating reagents with different shapes, and the stability in the box body is controlled within a certain range through the constant temperature cavity, so that the quality influence can not occur in the transportation process of the reagents, and meanwhile, the support plate is used for limiting the buffer sheet; the anti-shaking sponge is matched to contact the reagent, so that the shaking risk of the reagent is reduced; the temperature measuring unit through the temperature measuring groove monitors the internal temperature of the box body so as to ensure that the temperature can be known in an abnormal state.
The utility model discloses a box body leakproofness is guaranteed to the lid, and it is controllable to guarantee the backup pad inserted position through spacing groove and socket.
Gather the inside temperature of box body through the bar copper, change colour through irreversible heat-sensitive coating that discolours when the temperature surpasss safety range to when reagent takes out from the box body, can know that the box body temperature appears unusually, help avoiding the quality of reagent to appear the deviation.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic view of the installation of the support plate of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The technical solution of the present invention will be described clearly and completely through the following detailed description. It is to be understood that the specific embodiments described herein are merely illustrative of the invention, and that the described embodiments are merely some, not all, and are not intended to limit the invention.
Example 1:
referring to fig. 1 for expression, the embodiment of the present invention is a quality control transfer box for PCR detection reagent, comprising a box body 1, wherein the box body 1 is a conventional metal box body, the inner wall and the outer wall of the box body 1 can be stainless steel, and heat insulation foam is clamped between the inner wall and the outer wall of the box body 1; thereby reducing the influence of the outside temperature on the temperature inside the case 1.
An opening 2 is arranged at the upper part of the box body 1, and mounting parts 3 for placing reagents are distributed in the box body 1, wherein the mounting parts 3 are a plurality of cavities, and different reagents required by PCR detection are placed in different cavities; it should be noted that the preserved reagents are usually preserved at the same temperature, such as reaction solution, positive control reagent, negative control reagent, etc. are usually preserved at 0-30 ℃; wherein, the existing heat-conducting medium is filled between the mounting part 3 and the inner wall of the box body 1.
Be equipped with anti-shake sponge 4 in above-mentioned installation department 3, wherein the shell of anti-shake sponge 4 adopts the EVA material, makes anti-shake sponge 4 have sufficient toughness, and its anti-shake sponge 4 inside fills high-elastic material, bonds at the cavity inner wall of installation department 3 through glue, through the outer wall of anti-shake sponge 4 conflict reagent container to guarantee that reagent can not direct impact installation department 3's cavity inner wall in the transportation.
The bottom of the box body 1 is provided with a constant temperature cavity 5, a temperature control medium is injected into the constant temperature cavity 5, wherein the material of the contact part of the constant temperature cavity 5 and the installation part 3 can be a heat conduction material, and a heat bridge is generated between the temperature control medium in the constant temperature cavity 5 and the installation part 3, so that the temperature in the installation part 3 is controllable.
Above-mentioned 1 lateral wall of box body is equipped with socket 6, insert backup pad 7 in above-mentioned socket 6, wherein, accompany thermal-insulated foam between backup pad 7's inner wall and the outer wall, above-mentioned backup pad 7 is located installation department 3 tops, insert backup pad 7 through socket 6 promptly, its backup pad 7 is located between installation department 3 and the opening 2, be equipped with buffer plate 8 in above-mentioned installation department 3, the reagent of contradicting of 8 lower extremes of above-mentioned buffer plate, buffer plate 8 upper end conflict backup pad 7 lower extreme, therefore, backup pad 7's effect mainly compresses tightly buffer plate 8, make the buffer plate 8 can conflict the reagent in the installation department 3.
Put different reagents in the installation department 3 particularly, its reagent probably has the inconsistent condition of size, fills reagent and installation department 3's clearance through buffer wafer 8 and anti-shake sponge 4, because in the PCR experiment, the reagent is got and is put the order difference, consequently can follow the rear end through backup pad 7 and progressively take out reagent to socket 6, avoids reagent once only whole to take out and leads to the degree of difficulty increase that resets.
A temperature measuring groove 10 is arranged on one side of the mounting part 3, and a temperature measuring unit is arranged in the temperature measuring groove 10; wherein the temperature measuring groove 10 is a through hole arranged at one side of the mounting part 3, the side wall of the temperature measuring groove 10 is made of aluminum, and it should be noted that the temperature measuring groove 10 is at least contacted with the outer wall of one cavity of the mounting part 3, so that the temperature of the temperature measuring groove 10 is the same as that of the mounting part 3.
Example 2:
referring to the above embodiments, the present embodiment is different from the above embodiments in that: be equipped with lid 9 in above-mentioned opening 2, wherein lid 9 is the rubber material, and opening 2 is closed through lid 9 lid to 9 upper ends of the supporting plate 7 of contradicting of above-mentioned lid lower extreme to when the supporting plate 7 takes out, conflict buffer chip 8 realizes double-deck insurance effect.
Above-mentioned opening 2 is dwindled by upper end to lower extreme gradually, and wherein opening 2's minimum dimension is more than or equal to the width of installation department 3, and above-mentioned lid 9 is identical with opening 2, guarantees box body 1 leakproofness by lid 9, avoids external impurity or dust to fall into in the box body 1.
Example 3:
referring to the above embodiment, referring to fig. 2 for expression, the present embodiment is different from the above embodiment in that: a limiting groove 14 corresponding to the socket 6 is arranged on the side wall of the box body 1, a bulge 15 matched with the limiting groove 14 is arranged at the front end of the supporting plate 7, and the supporting plate 7 is limited by inserting the bulge 15 into the limiting groove 14; that is, the supporting plate 7 is inserted into the case 1 through the inserting hole 6, and then the supporting plate 7 is gradually inserted deep until the protrusion 15 of the front end of the supporting plate 7 is stopped by the stopping groove 14.
It should be noted that the supporting plate 7 is T-shaped, the rear end of the supporting plate 7 is provided with a contact plate, the contact plate contacts with the side wall of the box body 1, if necessary, the contact plate of the supporting plate 7 can be a magnetic plate, and the side wall of the box body 1 is provided with a magnet corresponding to the magnetic plate. Thereby further improving the stability of the support plate 7 after insertion.
Example 4:
referring to the above embodiments, the present embodiment is different from the above embodiments in that: the temperature measuring unit comprises a copper bar 11, and in order to ensure that the temperature of the copper bar 11 is the same as that of the mounting part 3, the copper bar 11 can contact the inner wall of the temperature measuring groove 10, and specifically, the inner diameter of the temperature measuring groove 10 is matched with the outer contour of the copper bar 11.
The surface of the copper bar 11 is covered with irreversible thermosensitive color-changing paint; the irreversible thermosensitive color-changing coating is the existing irreversible temperature-changing ink, the color-changing temperature range is selected according to the preservation requirement of a reagent, and the color-changing range of the temperature-changing ink which can be selected is usually more than 30 ℃.
Example 5:
referring to the above embodiments, the present embodiment is different from the above embodiments in that: more than two shunting shifting pieces 12 are arranged in the thermostatic chamber 5, and a passage is reserved between the two shunting shifting pieces 12. Divide thermostatic chamber 5 into two regions through reposition of redundant personnel plectrum 12, in its thermostatic chamber 5 jolt the in-process, accuse temperature medium can strike reposition of redundant personnel plectrum 12 to easily form the scouring effect, accuse temperature medium carries out the heat exchange back promptly, and local temperature has reduced, leaves 5 exchange places of thermostatic chamber far away accuse temperature medium, and the temperature does not descend, through striking process, is of value to accuse temperature medium and stabilizes the heat transfer.
Further, an injection opening is arranged on the side wall of the thermostatic chamber 5, a sealing plug 13 is arranged on the injection opening, and the sealing plug 13 is matched with the injection opening; the temperature control medium is supplemented through the injection port, the temperature control medium is liquid, and the sealing performance of the thermostatic cavity 5 is ensured through the sealing plug 13.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention, and is provided for the purpose of illustrating the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention.
In particular, any modification, equivalent substitution, variation and improvement in the component parts and/or arrangements of the subject combination arrangement, within the scope of the disclosure, drawings and claims, shall be included within the scope of protection of the present invention.
Claims (6)
1. The utility model provides a case is transported in accuse of article for PCR detect reagent, includes box body (1), box body (1) upper portion sets up opening (2), it has installation department (3) of placing reagent to be equipped with to distribute in box body (1), its characterized in that: be equipped with anti-shake sponge (4) in installation department (3), box body (1) bottom is equipped with thermostatic chamber (5), pour into the accuse temperature medium in thermostatic chamber (5), box body (1) lateral wall is equipped with socket (6), insert backup pad (7) in socket (6), backup pad (7) are located installation department (3) top, be equipped with buffer block (8) in installation department (3), buffer block (8) lower extreme conflict reagent, buffer block (8) upper end conflict backup pad (7) lower extreme, installation department (3) one side is equipped with temperature cell (10), the temperature measurement unit has been placed in temperature cell (10).
2. The quality-controlled transport cassette for PCR detection reagents according to claim 1, wherein: be equipped with lid (9) in opening (2), lid (9) lower extreme is contradicted backup pad (7) upper end, opening (2) dwindles gradually from upper end to lower extreme, lid (9) are identical with opening (2).
3. The quality-controlled transport cassette for PCR detection reagents according to claim 1, wherein: the side wall of the box body (1) is provided with a limiting groove (14) corresponding to the socket (6), the front end of the support plate (7) is provided with a bulge (15) matched with the limiting groove (14), and the support plate (7) is limited by inserting the bulge (15) into the limiting groove (14).
4. The quality-controlled transport cassette for PCR detection reagents according to claim 1, wherein: the temperature measuring unit comprises a copper bar (11), and the surface of the copper bar (11) is covered with irreversible thermochromic paint.
5. The quality-controlled transport cassette for PCR detection reagents according to claim 1, wherein: more than two shunting shifting pieces (12) are arranged in the thermostatic chamber (5), and a passage is reserved between the two shunting shifting pieces (12).
6. The quality-controlled transport cassette for PCR detection reagents according to claim 1, wherein: the side wall of the constant temperature cavity (5) is provided with an injection opening, the injection opening is provided with a sealing plug (13), and the sealing plug (13) is matched with the injection opening.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021876675.XU CN214058286U (en) | 2020-09-01 | 2020-09-01 | A quality control transports box for PCR detect reagent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021876675.XU CN214058286U (en) | 2020-09-01 | 2020-09-01 | A quality control transports box for PCR detect reagent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214058286U true CN214058286U (en) | 2021-08-27 |
Family
ID=77385378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021876675.XU Expired - Fee Related CN214058286U (en) | 2020-09-01 | 2020-09-01 | A quality control transports box for PCR detect reagent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214058286U (en) |
-
2020
- 2020-09-01 CN CN202021876675.XU patent/CN214058286U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210827 |