CN213956952U - Special slide glass of full-automatic immunohistochemical staining appearance - Google Patents

Special slide glass of full-automatic immunohistochemical staining appearance Download PDF

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Publication number
CN213956952U
CN213956952U CN202022686860.9U CN202022686860U CN213956952U CN 213956952 U CN213956952 U CN 213956952U CN 202022686860 U CN202022686860 U CN 202022686860U CN 213956952 U CN213956952 U CN 213956952U
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district
area
workspace
label
immunohistochemical staining
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CN202022686860.9U
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彭俊
黄燕华
崔娇娇
苗凤杰
秦蕾
汪中厅
吴德
黄牧一
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Wuhan Jiayuan Biomedical Engineering Co ltd
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Wuhan Jiayuan Biomedical Engineering Co ltd
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Abstract

The utility model discloses a special slide glass of full-automatic immunohistochemical staining appearance, it includes the slide main part, the district is puted up for handheld district, workspace and label from the front end to the rear end in proper order to the upper surface of slide main part, handheld district and label are puted up the district upper surface and are dull polish surface and all be higher than the upper surface of workspace, the middle coating of workspace has the observation guard area that comprises hydrophobic coating, the rear end of handheld district upper surface through first cambered surface changeover portion with the front end of workspace upper surface is connected, the rear end of workspace upper surface through second cambered surface changeover portion with the front end of district upper surface is puted up to the label is connected. The liquid in the working area is not easy to flow to the two ends to pollute the handheld area and the label pasting area; the middle hydrophobic coating of the working area can effectively prevent the cell or tissue from falling off during the operation process.

Description

Special slide glass of full-automatic immunohistochemical staining appearance
Technical Field
The utility model belongs to the biomedical field, concretely relates to special slide glass of full-automatic immunohistochemical staining appearance.
Background
The immunohistochemical slide glass is also called as anti-drop slide glass, ion modified slide glass or cell capture slide glass, and is characterized in that the surface of the slide glass or cover glass is modified by a chemical or physical method so as to prevent the cell or tissue from dropping in the operation process. At present, the domestic commonly used full-automatic immunohistochemical stainers are brands such as Roche, Lecia, Dako, Thermo, Biocare, Biogene and the like, and domestic glass slides are usually selected for reducing the cost when matched glass slides are used in the instruments, but the domestic glass slides need to be additionally processed before being loaded, so that the instruments are complicated. Therefore, it is necessary to design a special slide glass suitable for the staining apparatus, which simplifies the processing steps and improves the efficiency.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a special slide glass of full-automatic immunohistochemical staining appearance aims at overcoming current ordinary domestic slide glass and need carry out special materialization before operating the computer and handle and the complex operation that leads to and the inefficiency not enough.
The utility model provides an above-mentioned technical problem's technical scheme as follows: the utility model provides a special slide glass of full-automatic immunohistochemical staining appearance, it includes the slide main part, the district is posted for handheld district, workspace and label from front end to rear end in proper order to the upper surface of slide main part, the district upper surface is posted to handheld district and label and is dull polish surface and all is higher than the upper surface of workspace, the middle coating of workspace has the observation guard area who constitutes by hydrophobic coating, the rear end of handheld district upper surface through first cambered surface changeover portion with the front end of workspace upper surface is connected, the rear end of workspace upper surface through second cambered surface changeover portion with the front end of district upper surface is posted to the label is connected.
On the basis of the technical scheme, the utility model discloses can also do following improvement.
Furthermore, a round or square protective groove is formed in the middle of the working area, and a hydrophobic material is coated and filled in the protective groove to form the hydrophobic coating.
The beneficial effect of adopting above-mentioned further scheme is that, after setting up the protective tank, the border of observing the guard area is clear, and the coating of the hydrophobic coating of being convenient for also directly places cell, tissue etc. in this region when being convenient for use.
Further, the upper surface of the hydrophobic coating is lower than the upper surface of the working area at the periphery of the protective groove and has a height difference within 0.5 mm.
The beneficial effect who adopts above-mentioned further scheme is that, the peripheral workspace upper surface of protective tank is higher than the hydrophobic coating upper surface in the protective tank, then except that assembling of hydrophobic coating prevents that the tissue from flowing to the periphery and taking off the piece, the cell wall of protective tank also has certain effect of blockking, and the anti-separation piece effect is better.
Further, the upper surface of the hydrophobic coating is flush with the upper surface of the working area at the periphery of the protective groove.
The further scheme has the beneficial effects that when the tissue cells are very thin, if the upper surface of the hydrophobic coating is lower than the surface of the peripheral working area, after the cover glass is covered, the bottom surface of the cover glass can not be effectively attached to the tissue, and bubbles can be generated, so that the flush state is favorable for the use of the cover glass under the condition.
Furthermore, the protective groove is a frustum-shaped groove with a large upper end and a small lower end, and the depth of the protective groove is 0.5-1.5 mm.
The beneficial effect of adopting above-mentioned further scheme is that, frustum form groove is more pleasing to the eye and can save the use of hydrophobic coating material.
Further, in the front-rear direction, the length of the hand-held area is 1/3-1/4 of the workspace length, and the length of the label posting area is 1/4-1/5 of the workspace length.
The beneficial effect of adopting above-mentioned further scheme is that, above-mentioned length proportion is more suitable, and the function homoenergetic of each region is better guaranteed.
Further, the upper surface in handheld district and the district is posted to the label is than the upper surface in workspace is 0.5-1.5mm higher.
Adopt above-mentioned further scheme's beneficial effect be, handheld district and label are puted up the district and should not be too high or low excessively, and too high then extravagant material and accomodate inconveniently, low then can not reach the effect of being convenient for to take to hold between fingers.
Compared with the prior art, the utility model discloses a technological effect and advantage:
the handheld area and the label pasting area are arranged, the two areas are thicker relative to the working area in the middle, on one hand, fingers can be conveniently held by the thicker handheld area from the left side and the right side, meanwhile, the handheld area and the working area are obviously separated, the hands are not easy to cross the boundary to pollute the working area when the fingers are held, and on the other hand, liquid in the working area is not easy to flow to the two ends to pollute the handheld area and the label pasting area; the arrangement of the first cambered surface transition section and the second cambered surface transition section can avoid the sharp edges and corners at the edges of the handheld area and the label pasting area from hurting hands, is more attractive and is not easy to break at the edges; the observation protection area formed by the hydrophobic coating in the middle of the working area can enable tissue cells, dye liquor and the like to be observed to be gathered on the hydrophobic coating, and the phenomenon that the cells or the tissues fall off in the operation process is prevented.
Drawings
FIG. 1 is a top view of a slide glass specially used for a full-automatic immunohistochemical staining apparatus provided by the present invention;
FIG. 2 is a left side view of a slide specific to the fully automated immunohistochemical staining apparatus of FIG. 1;
FIG. 3 is a schematic view of FIG. 2 taken along section line A-A;
FIG. 4 is a schematic view of the hydrophobic coating of FIG. 3 with the upper surface below the upper surface of its peripheral working area;
FIG. 5 is a schematic view of the shield bath of FIG. 3 without a hydrophobic coating.
In the drawings, the components represented by the respective reference numerals are listed below:
1. a handheld area; 2. a working area; 3. a label posting area; 4. observing the protection area; 5. a hydrophobic coating; 6. a protective bath; 7. a first cambered surface transition section; 8. a second cambered surface transition section.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, if terms indicating orientation such as "upper", "lower", "left", "right", "top", "bottom", "inner", "outer", etc. are used, the indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, but does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
As shown in fig. 1 to 5, the utility model provides a special slide glass of full-automatic immunohistochemical staining appearance, it includes the slide main part, the upper surface of slide main part is handheld district 1, workspace 2 and label from the front end to the rear end in proper order and posts district 3, handheld district 1 and label post 3 upper surfaces and be dull polish surface and all be higher than workspace 2's upper surface, workspace 2's middle coating has observation guard area 4 by hydrophobic coating 5 constitution, handheld district 1 upper surface's rear end through first cambered surface changeover portion 7 with workspace 2 upper surface's front end is connected, workspace 2 upper surface's rear end through second cambered surface changeover portion 8 with the label posts the front end of district 3 upper surfaces and connects.
It should be noted that, the sanding treatment of handheld district and label posting district makes it more obvious with the workspace on the one hand, and on the other hand increases the friction, is difficult for the slippage after picking up.
In an embodiment of the present invention, a circular or square protective groove 6 is disposed in the middle of the working area 2, and the protective groove 6 is coated with a hydrophobic material to form the hydrophobic coating 5.
It should be noted that the processing of the shield groove may be performed by chemical etching or physical polishing.
On the basis of the above embodiment, as shown in fig. 4, the upper surface of the hydrophobic coating 5 is lower than the upper surface of the working area 2 around the shield groove 6 by a height difference of 0.5mm or less.
As another alternative, as shown in fig. 3, the upper surface of the hydrophobic coating 5 is flush with the upper surface of the working area 2 around the shield bath 6.
Further, as shown in fig. 5, the protective groove 6 is a frustum-shaped groove with a large upper end and a small lower end, and the depth of the protective groove 6 is 0.5-1.5 mm.
In the above embodiments, the length of the hand-held area 1 is 1/3 to 1/4 of the length of the work area 2, and the length of the label posting area 3 is 1/4 to 1/5 of the length of the work area 2 in the front-rear direction. The upper surface of handheld district 1 and the district 3 is posted to the label compares the upper surface of workspace 2 is higher 0.5-1.5 mm.
The basic principle of the utility model is that the glass slide is arranged into three sections from front to back, the front end is a hand-held area which is thicker than the middle working area, and the glass slide can be conveniently held by hands to be lifted or clamped by tweezers; the rear end is a label pasting area, and a label corresponding to the name of the corresponding tissue or cell in the working area can be pasted, so that the identification and the use are convenient; the central area of the middle working area is provided with an observation protection area formed by a hydrophobic coating, and the hydrophobic effect enables liquid containing tissues or cells to gather in the area, so that the phenomenon of falling of the slice is effectively avoided; both ends all are higher than the workspace in the middle, are held between the fingers and are difficult for polluting middle workspace when getting, and the liquid of middle workspace is also difficult for running to both ends, and anti-pollution is effectual.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims (7)

1. The utility model provides a special slide glass of full-automatic immunohistochemical staining appearance, a serial communication port, including the slide main part, the upper surface of slide main part is handheld district (1), workspace (2) and label from the front end to the rear end in proper order and posts district (3), handheld district (1) and label post district (3) upper surface and be dull polish surface and all be higher than the upper surface of workspace (2), the middle coating of workspace (2) has observation guard area (4) of constituting by hydrophobic coating (5), the rear end of handheld district (1) upper surface through first cambered surface changeover portion (7) with the front end of workspace (2) upper surface is connected, the rear end of workspace (2) upper surface through second cambered surface changeover portion (8) with the front end connection of district (3) upper surface is posted to the label.
2. The slide special for the full-automatic immunohistochemical staining instrument according to claim 1, wherein a circular or square protective groove (6) is formed in the middle of the working area (2), and the protective groove (6) is coated and filled with a hydrophobic material to form the hydrophobic coating (5).
3. The slide special for the fully automatic immunohistochemical staining instrument according to claim 2, wherein the upper surface of the hydrophobic coating (5) is lower than the upper surface of the working area (2) at the periphery of the protective groove (6) and within 0.5mm of height difference.
4. The slide special for the fully automatic immunohistochemical staining instrument according to claim 2, wherein the upper surface of the hydrophobic coating (5) is flush with the upper surface of the working area (2) around the protection tank (6).
5. The slide glass special for the full-automatic immunohistochemical staining instrument according to claim 2, wherein the protective groove (6) is a frustum-shaped groove with a large upper end and a small lower end, and the depth of the protective groove (6) is 0.5-1.5 mm.
6. A slide glass dedicated to a fully automatic immunohistochemical staining apparatus according to claim 1, wherein the length of the hand-held area (1) is 1/3 to 1/4 of the length of the working area (2) and the length of the label posting area (3) is 1/4 to 1/5 of the length of the working area (2) in the front-back direction.
7. The slide glass special for the fully automatic immunohistochemical staining apparatus according to any one of claims 1 to 6, wherein the upper surface of the hand-held area (1) and the label pasting area (3) is 0.5-1.5mm higher than the upper surface of the working area (2).
CN202022686860.9U 2020-11-19 2020-11-19 Special slide glass of full-automatic immunohistochemical staining appearance Active CN213956952U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202022686860.9U CN213956952U (en) 2020-11-19 2020-11-19 Special slide glass of full-automatic immunohistochemical staining appearance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202022686860.9U CN213956952U (en) 2020-11-19 2020-11-19 Special slide glass of full-automatic immunohistochemical staining appearance

Publications (1)

Publication Number Publication Date
CN213956952U true CN213956952U (en) 2021-08-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202022686860.9U Active CN213956952U (en) 2020-11-19 2020-11-19 Special slide glass of full-automatic immunohistochemical staining appearance

Country Status (1)

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CN (1) CN213956952U (en)

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