CN110161673A - Integral type slide suit and its manufacturing method - Google Patents

Integral type slide suit and its manufacturing method Download PDF

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Publication number
CN110161673A
CN110161673A CN201910454702.XA CN201910454702A CN110161673A CN 110161673 A CN110161673 A CN 110161673A CN 201910454702 A CN201910454702 A CN 201910454702A CN 110161673 A CN110161673 A CN 110161673A
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CN
China
Prior art keywords
checked
slide
integral type
pond
suit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910454702.XA
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Chinese (zh)
Inventor
王振刚
吴涛
黄炜中
梁桂彬
赵明建
刘波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guateng Technology (shenzhen) Co Ltd
Original Assignee
Guateng Technology (shenzhen) Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guateng Technology (shenzhen) Co Ltd filed Critical Guateng Technology (shenzhen) Co Ltd
Priority to CN201910454702.XA priority Critical patent/CN110161673A/en
Publication of CN110161673A publication Critical patent/CN110161673A/en
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/34Microscope slides, e.g. mounting specimens on microscope slides

Abstract

The embodiment of the invention discloses a kind of integral type slide suit and its manufacturing methods, the slide suit includes micro slide and coverslip, micro slide is equipped with region to be checked, one or more ponds to be checked are equipped in region to be checked, side on micro slide positioned at pond to be checked is equipped with sample application zone, the other side on micro slide positioned at pond to be checked is equipped with gas vent, and sample application zone and gas vent are connected to pond to be checked, and coverslip is covered on region to be checked.The present invention can reduce laboratory, scientific research institution, the material procurement of hospital, storage, management cost;Keep sample to be examined production method simpler, it is time-consuming less;The manufacturing technology threshold for reducing sample to be examined, does not need higher professional technique, keeps the production of sample to be examined safer.

Description

Integral type slide suit and its manufacturing method
Technical field
The present invention relates to biology, the field of medical instrument technology more particularly to a kind of integral type slide suit and its manufacturers Method.
Background technique
Currently in pattern detection analytic process, most of lab assistant, hospital reviewer be first to take out loading Then piece uses pin tool, the quantitative sample of addition is then placed in coverslip, covered after uniformly smearing, and uses suction Water paper blots the surplus liquid sample or coloring agent of periphery spilling, on the observation instrument being then placed in or equipment.It is this production to The complex procedures for examining slide, take a long time, operator are needed to have higher professional technique, while also having to the capacity of sample-adding very high Requirement;In addition, big multisample is all infectiousness, highly pathogenic, the danger such as corrosivity.
Summary of the invention
The technical problem to be solved by the embodiment of the invention is that providing a kind of integral type slide suit and its manufacturer Method manufactures the processing step of sample to be examined, reduces to the pollution and injury of operator or instrument, promotes sample-adding amount so as to simplify Precision.
In order to solve the above-mentioned technical problem, the embodiment of the present invention proposes a kind of integral type slide suit, includes loading Piece and coverslip, micro slide are equipped with region to be checked, are equipped with one or more ponds to be checked in region to be checked, on micro slide positioned to The side for examining pond is equipped with sample application zone, and the other side that pond to be checked is located on micro slide is equipped with gas vent, sample application zone and gas vent with Pond connection to be checked, coverslip are covered on region to be checked.
Further, region to be checked is also provided with overflow launder, and the one end in pond to be checked offers overflow hole, overflow hole and overflow Slot connection.
Further, overflow launder is through slot.
Further, when pond to be checked is multiple, isolation channel is offered between each pond to be checked.
Further, the micro slide bottom is equipped with escape groove.
Further, micro slide is equipped with multiple for clasping the blanching point of coverslip.
Further, one jiao of micro slide is provided with chamfering.
Further, the depth in the pond to be checked is 0.05-0.15mm.
Further, micro slide is integrally formed using transparent plastic.
Correspondingly, the embodiment of the invention also provides a kind of manufacturing methods of integral type slide suit, comprising:
Step 1: production micro slide being integrally formed using transparent plastic, coverslip is produced using glass material, wherein loading On piece is located at area peripheral edge to be checked equipped with multiple blanching points;
Step 2: coverslip is placed on the region to be checked of micro slide;
Step 3: blanching being carried out to blanching point on micro slide using preset temperature, is suppressed after blanching preset time, after cooling Obtain integral type slide suit.
The invention has the benefit that can reduce laboratory, scientific research institution, hospital material procurement, storage (with Before need to be stored separately glass slide and coverslip), management cost;Keep sample to be examined production method simpler, it is time-consuming less;Drop The manufacturing technology threshold of low sample to be examined, does not need higher professional technique, keeps the production of sample to be examined safer.
Detailed description of the invention
Fig. 1 is the structure chart of the integral type slide suit of the embodiment of the present invention.
Fig. 2 is the main view of the integral type slide suit of the embodiment of the present invention.
Fig. 3 is the sectional view in Fig. 2 at A-A.
Fig. 4 is the main view of the micro slide of the embodiment of the present invention.
Fig. 5 is the rearview of the micro slide of the embodiment of the present invention.
Fig. 6 is the flow diagram of the manufacturing method of the integral type slide suit of the embodiment of the present invention.
Specific embodiment
It should be noted that in the absence of conflict, the features in the embodiments and the embodiments of the present application can phase It mutually combines, invention is further described in detail in the following with reference to the drawings and specific embodiments.
If directional instruction (such as up, down, left, right, before and after ...) is only used for explaining at certain in the embodiment of the present invention Relative positional relationship, motion conditions etc. under one particular pose (as shown in the picture) between each component, if the particular pose is sent out When raw change, then directionality instruction also correspondingly changes correspondingly.
If in addition, the description for being related to " first ", " second " etc. in the present invention is used for description purposes only, and should not be understood as Its relative importance of indication or suggestion or the quantity for implicitly indicating indicated technical characteristic.Define as a result, " first ", The feature of " second " can explicitly or implicitly include at least one of the features.
FIG. 1 to FIG. 5 is please referred to, the integral type slide suit of the embodiment of the present invention includes micro slide 10 and coverslip 20.
Micro slide 10 is equipped with region to be checked, is equipped with one or more ponds 11 to be checked in region to be checked.Preferably 2 to be checked Pond 11.One end of micro slide 10 is additionally provided with identified areas 17, and identified areas 17 can be used to print Logo etc., and identified areas 17 convenient for manual operation.Coverslip 20 is made of glass, and preferred size specification is 35mmx18mm, with a thickness of 0.17-0.3mm.
Side on micro slide 10 positioned at pond 11 to be checked is equipped with sample application zone 12, each corresponding sample application zone in pond 11 to be checked 12.In use, sample to be detected is added to sample application zone 12 by liquid-transfering device, sample to be detected is filled by diffusion to be checked Pond 11, convenient for observing under the microscope.The other side on micro slide 10 positioned at pond 11 to be checked is equipped with gas vent 13, convenient for be detected When sample is filled, gas extra in pond 11 to be checked is discharged.Since there are air in pond 11 to be checked, if without gas vent 13, Air in pond 11 to be checked can block pond 11 to be checked, make process of the sample to be detected from the diffusion filling of sample application zone 12 to pond 11 to be checked Very slowly, and it is easy that there are bubbles in pond to be checked 11;The present invention makes sample to be detected from sample application zone by setting gas vent 13 The air in pond 11 to be checked can be discharged when 12 diffusion fillings to pond 11 to be checked easily, to accelerate sample to be detected from sample application zone 12 diffusions are filled to the process in entire pond 11 to be checked.Sample application zone 12 and gas vent 13 are connected to pond 11 to be checked, and coverslip 20 covers On region to be checked.
As an implementation, region to be checked is also provided with overflow launder 14, and the one end in pond 11 to be checked offers overflow hole 15, overflow hole 15 is connected to overflow launder 14.After sample has been filled in pond 11 to be checked, excessive sample can be imported by overflow hole 15 In overflow launder 14, reduces and polluted caused by sample-adding excess.Overflow launder 14 of the invention makes sample-adding amount controllable, and does not easily cause dirt Dye.
As an implementation, overflow launder 14 is through slot.
As an implementation, when pond 11 to be checked is multiple, isolation channel 16 is offered between each pond 11 to be checked.When to be checked When pond 11 has 2 or 2 or more, isolation channel 16 can be avoided cross contamination between the pond 11 to be checked of adjacent 2, avoid mistake Testing result accidentally.
As an implementation, 10 bottom of micro slide is equipped with escape groove 30.When integral type slide is set with superposition storage, Escape groove 30 can reduce integral type slide and be set with the risk scratched.
As an implementation, micro slide 10 is equipped with multiple for clasping the blanching point 18 of coverslip 20.Blanching point 18 be preferably 4, is respectively correspondingly arranged in the outside at 4 angles in region to be checked.After carrying out local heating to blanching point 18, blanching point 18 It is suppressed, is generated pyroplastic deformation (part of blanching point 18 is extruded on coverslip 20) after softening, after cooling, blanching point Coverslip 20 is clasped fixation by 18.
As an implementation, one jiao of micro slide 10 is provided with chamfering 19.Chamfering 19 is fool-proof design, convenient for stacking It piles up.
As an implementation, the depth in the pond to be checked 11 is 0.05-0.15mm.Preferably 0.08mm.
As an implementation, micro slide 10 is integrally formed using transparent plastic (PMMA, PC, PS etc.).It is preferred that Using PMMA material.
Please refer to Fig. 6, the manufacturing method of the integral type slide suit of the embodiment of the present invention, for manufacturing above-mentioned integral type Slide suit, including step 1~step 3.
Step 1: production micro slide 10 is integrally formed using transparent plastic, coverslip 20 is produced using glass material, Wherein, area peripheral edge to be checked is located on micro slide 10 and is equipped with multiple blanching points 18.10 structure of micro slide is above-mentioned integral type glass The micro slide 10 of piece suit.Blanching point 18 is preferably 4, is respectively arranged on the outside corresponding position at 4 angles in region to be checked.
Step 2: coverslip 20 is placed on the region to be checked of micro slide 10.
Step 3: blanching being carried out to blanching point 18 on micro slide 10 using preset temperature, is pressed after blanching preset time System obtains integral type slide suit after cooling.After the present invention carries out local blanching heating preset time to blanching point 18, blanching point 18 soften, and extrude to blanching point 18, so that blanching point 18 is generated pyroplastic deformation, and then be squeezed a part of blanching point 18 It is depressed on coverslip 20, after cooling, coverslip 20 is clasped fixation by blanching point 18, completes the manufacture of integral type slide suit.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention are defined by the appended claims and their equivalents.

Claims (10)

1. a kind of integral type slide suit, includes micro slide and coverslip, which is characterized in that micro slide is equipped with area to be checked Domain is equipped with one or more ponds to be checked in region to be checked, and the side that pond to be checked is located on micro slide is equipped with sample application zone, on micro slide The other side positioned at pond to be checked is equipped with gas vent, and sample application zone and gas vent are connected to pond to be checked, and coverslip is covered on area to be checked On domain.
2. integral type slide suit as described in claim 1, which is characterized in that region to be checked is also provided with overflow launder, to be checked The one end in pond offers overflow hole, and overflow hole is connected to overflow launder.
3. integral type slide suit as claimed in claim 2, which is characterized in that overflow launder is through slot.
4. integral type slide suit as described in claim 1, which is characterized in that when pond to be checked is multiple, between each pond to be checked Offer isolation channel.
5. integral type slide suit as described in claim 1, which is characterized in that the micro slide bottom is equipped with escape groove.
6. integral type slide suit as described in claim 1, which is characterized in that micro slide is equipped with multiple for clasping lid glass The blanching point of piece.
7. integral type slide suit as described in claim 1, which is characterized in that one jiao of micro slide is provided with chamfering.
8. integral type slide suit as described in claim 1, which is characterized in that the depth in the pond to be checked is 0.05- 0.15mm。
9. as integral type slide of any of claims 1-8 is set with, which is characterized in that micro slide uses transparent plastic It is integrally formed.
10. a kind of manufacturing method of integral type slide suit characterized by comprising
Step 1: production micro slide being integrally formed using transparent plastic, coverslip is produced using glass material, wherein loading On piece is located at area peripheral edge to be checked equipped with multiple blanching points;
Step 2: coverslip is placed on the region to be checked of micro slide;
Step 3: blanching being carried out to blanching point on micro slide using preset temperature, is suppressed after blanching preset time, after cooling Obtain integral type slide suit.
CN201910454702.XA 2019-05-29 2019-05-29 Integral type slide suit and its manufacturing method Pending CN110161673A (en)

Priority Applications (1)

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CN201910454702.XA CN110161673A (en) 2019-05-29 2019-05-29 Integral type slide suit and its manufacturing method

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110673324A (en) * 2019-09-27 2020-01-10 佛山科学技术学院 Glass slide structure suitable for confocal microscope

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4624882A (en) * 1982-11-15 1986-11-25 Sybron Corporation Microscope slide with raised marking surface
CN201279395Y (en) * 2008-10-09 2009-07-29 邱剑波 Assembling toy
JP2010197425A (en) * 2009-02-23 2010-09-09 Matsunami Glass Kogyo Kk Cover glass
CN202757874U (en) * 2012-08-08 2013-02-27 青岛华晶生物技术有限公司 Body fluid sample special quantitative detection slide
CN104266973A (en) * 2014-10-13 2015-01-07 中国科学技术大学 Permanent liquid-state microsphere sample chamber
CN205808905U (en) * 2016-06-29 2016-12-14 珠海科域生物工程股份有限公司 A kind of counting chamber with degassing function
CN206773289U (en) * 2017-03-30 2017-12-19 山东泰诺生物科技有限公司 The special secretion analyte detection slide of integration
CN107576661A (en) * 2017-09-08 2018-01-12 湖南友哲科技有限公司 Two-chamber pelletizer and preparation method for gynaecology's microscope detection
CN208888123U (en) * 2018-09-19 2019-05-21 宁波摩米创新工场电子科技有限公司 A kind of medical counting chamber of disposable microscope
CN209821493U (en) * 2019-05-29 2019-12-20 瓜藤科技(深圳)有限公司 Integrated slide set

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4624882A (en) * 1982-11-15 1986-11-25 Sybron Corporation Microscope slide with raised marking surface
CN201279395Y (en) * 2008-10-09 2009-07-29 邱剑波 Assembling toy
JP2010197425A (en) * 2009-02-23 2010-09-09 Matsunami Glass Kogyo Kk Cover glass
CN202757874U (en) * 2012-08-08 2013-02-27 青岛华晶生物技术有限公司 Body fluid sample special quantitative detection slide
CN104266973A (en) * 2014-10-13 2015-01-07 中国科学技术大学 Permanent liquid-state microsphere sample chamber
CN205808905U (en) * 2016-06-29 2016-12-14 珠海科域生物工程股份有限公司 A kind of counting chamber with degassing function
CN206773289U (en) * 2017-03-30 2017-12-19 山东泰诺生物科技有限公司 The special secretion analyte detection slide of integration
CN107576661A (en) * 2017-09-08 2018-01-12 湖南友哲科技有限公司 Two-chamber pelletizer and preparation method for gynaecology's microscope detection
CN208888123U (en) * 2018-09-19 2019-05-21 宁波摩米创新工场电子科技有限公司 A kind of medical counting chamber of disposable microscope
CN209821493U (en) * 2019-05-29 2019-12-20 瓜藤科技(深圳)有限公司 Integrated slide set

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110673324A (en) * 2019-09-27 2020-01-10 佛山科学技术学院 Glass slide structure suitable for confocal microscope
CN110673324B (en) * 2019-09-27 2022-04-26 佛山科学技术学院 Glass slide structure suitable for confocal microscope

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