CN213885259U - Filter equipment is used in heparin sodium production - Google Patents
Filter equipment is used in heparin sodium production Download PDFInfo
- Publication number
- CN213885259U CN213885259U CN202022395819.6U CN202022395819U CN213885259U CN 213885259 U CN213885259 U CN 213885259U CN 202022395819 U CN202022395819 U CN 202022395819U CN 213885259 U CN213885259 U CN 213885259U
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- CN
- China
- Prior art keywords
- filtering
- barrel
- heparin sodium
- circulation
- feed liquor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920000669 heparin Polymers 0.000 title claims abstract description 19
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 title claims abstract description 19
- 229960001008 heparin sodium Drugs 0.000 title claims abstract description 19
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 238000001914 filtration Methods 0.000 claims abstract description 40
- 238000001179 sorption measurement Methods 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000000919 ceramic Substances 0.000 claims description 10
- 239000012528 membrane Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 230000001105 regulatory effect Effects 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 108010019160 Pancreatin Proteins 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229940055695 pancreatin Drugs 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
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- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The utility model discloses a filter equipment is used in heparin sodium production, it is including filtering barrel, circulation feed liquor pipe and circulation drain pipe, and circulation feed liquor pipe is connected to the lower extreme of filtering the barrel, and the upper end of filtering the barrel is connected to circulation drain pipe through circulating water pump, and the electromagnetic adsorption piece is connected through the connecting rod in the outside of filtering the barrel. The beneficial effects of the utility model are that: the device is arranged on the wall of the enzymolysis tank, the material is guided into the filtering device through a pipeline, and the filtered material enters the enzymolysis tank again through the pipeline for circular filtration, so that the filtering effect is good; the materials do not need to be conveyed remotely, so that the operation steps are greatly simplified; adopt the electromagnetic adsorption piece to adsorb on the enzymolysis tank, it is convenient to load and unload.
Description
Technical Field
The utility model relates to a filter equipment is used in heparin sodium production belongs to heparin sodium production facility technical field.
Background
The enzymolysis process of heparin sodium includes the first stirring the said material, regulating pH value to 8-9 with small amount of dilute alkali solution, adding fresh pancreatin as enzymolysis agent, stirring, slowly raising the temperature to about 40 deg.c, stirring while maintaining pH value of the material liquid at 7.5-8, maintaining the temperature at 37-40 deg.c for 3-4 hr, raising the temperature to 47-50 deg.c, maintaining pH value at 8.0-8.5, replenishing small amount of pancreatin, enzymolysis for 4-5 hr, regulating pH value with hydrochloric acid to 5.5-6, raising the temperature to 80 deg.c, adding refined salt in 5 wt% of the material liquid while stirring to mix homogeneously, raising temperature to 90 deg.c, maintaining the temperature for 30 min, stopping stirring, hot filtering to eliminate impurity, cooling the filtrate to 37 deg.c, regulating pH value with dilute alkali solution to 10.5, fine filtering, and adjusting the pH of the filtrate to 9.0-9.5 for ion exchange adsorption treatment. Need filter when the enzymolysis to a certain extent and detach impurity in the heat, get back to the enzymolysis tank again and carry out the enzymolysis, the mode of present adoption is in carrying the material to filter equipment, accomplish again after filtering and carry the material can the enzymolysis tank in, the ejection of compact of feeding in the enzymolysis tank of frequent follow like this, complex operation.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model lies in providing a filter equipment is used in heparin sodium production, and this filter equipment installs on the enzymolysis tank wall, through the pipeline with the leading-in filter equipment of material, through in the pipeline reentrant enzymolysis tank after filtering, carries out the loop filter, and the filter effect is good, and the material need not remote transport, has simplified operating procedure greatly.
The utility model discloses a following scheme realizes: the utility model provides a filter equipment is used in heparin sodium production, its includes filters barrel, circulation feed liquor pipe and circulation drain pipe, the lower extreme of filtering the barrel is connected circulation feed liquor pipe, the upper end of filtering the barrel is connected to through circulating water pump circulation drain pipe, the electromagnetic adsorption piece is connected through the connecting rod in the outside of filtering the barrel.
The electromagnetic adsorption blocks are two and are respectively connected with the filtering cylinder body through the connecting rods.
And a filter screen is arranged in the filter cylinder body and is positioned above the circulating liquid inlet pipe.
And a ceramic membrane component is arranged in the filtering cylinder and is positioned above the filter screen.
The ceramic membrane module is positioned below the circulating water pump.
The utility model has the advantages that:
1. the utility model relates to a filter equipment for producing heparin sodium is installed on the wall of an enzymolysis tank, the material is guided into the filter equipment through a pipeline, and the filtered material enters the enzymolysis tank again through the pipeline for circular filtration, and the filter effect is good;
2. the material of the filtering device for producing the heparin sodium does not need to be conveyed remotely, so that the operation steps are greatly simplified;
3. the utility model relates to a filter equipment is used in heparin sodium production adopts the electromagnetic adsorption piece to adsorb on the enzymolysis tank, and it is convenient to load and unload.
Drawings
Fig. 1 is a schematic view of a front cross-sectional structure of the filtering device for producing heparin sodium of the present invention.
Fig. 2 is a schematic side view of the filtering device for producing heparin sodium of the present invention.
In the figure: 1 is a filtering cylinder body, 2 is a circulating liquid inlet pipe, 3 is a circulating liquid outlet pipe, 4 is a circulating water pump, 5 is a connecting rod, 6 is an electromagnetic adsorption block, 7 is a filter screen, and 8 is a ceramic membrane component.
Detailed Description
The present invention will be further described with reference to fig. 1-2, but the scope of the present invention is not limited to the description.
In which like parts are designated by like reference numerals. It is noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component, and the drawings are in greatly simplified form and employ non-precise ratios, merely for the purpose of facilitating and distinctly aiding in the description of the embodiments of the present invention.
In the following description, for purposes of clarity, not all features of an actual implementation are described, well-known functions or constructions are not described in detail since they would obscure the invention with unnecessary detail, it being understood that in the development of any actual embodiment, numerous implementation details must be set forth in order to achieve the developer's specific goals, such as compliance with system-related and business-related constraints, changing from one implementation to another, and it being recognized that such development efforts may be complex and time consuming, but would nevertheless be a routine undertaking for those of ordinary skill in the art.
The utility model provides a filter equipment is used in heparin sodium production, it is including filtering barrel 1, circulation feed liquor pipe 2 and circulation drain pipe 3, circulation feed liquor pipe 2 is connected to the lower extreme of filtering barrel 1, the upper end of filtering barrel 1 is connected to circulation drain pipe 3 through circulating water pump 4, the outside of filtering barrel 1 is passed through connecting rod 5 and is connected electromagnetic adsorption piece 6, electromagnetic adsorption piece 6 is equipped with two, be connected with filtering barrel 1 through connecting rod 5 respectively, be equipped with filter screen 7 in the filtering barrel 1, filter screen 7 is located circulation feed liquor pipe 2's top, be equipped with ceramic membrane subassembly 8 in the filtering barrel 1, ceramic membrane subassembly 8 is located the top of filter screen 7, ceramic membrane subassembly 8 is located circulating water pump 4's below.
During the use, filter barrel 1 and pass through electromagnetic adsorption piece 6 absorption on the enzymolysis tank, be connected circulation feed liquor pipe 2 and circulation drain pipe 3 with the enzymolysis tank through the pipe, material in the enzymolysis tank passes through the pipe and gets into circulation feed liquor pipe 2, then filters through filter screen 7 and ceramic membrane subassembly 8 in proper order, get back to the enzymolysis tank again from circulation drain pipe 3 in, electromagnetic adsorption piece 6 then adsorbs on the enzymolysis tank, belong to current well-known technique, its inner structure, theory of operation and course of work are no longer repeated here.
Although the invention has been shown and described in detail with respect to the preferred embodiments thereof, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (5)
1. The utility model provides a filter equipment is used in heparin sodium production which characterized in that: it is including filtering barrel (1), circulation feed liquor pipe (2) and circulation drain pipe (3), the lower extreme of filtering barrel (1) is connected circulation feed liquor pipe (2), the upper end of filtering barrel (1) is connected to through circulating water pump (4) circulation drain pipe (3), the outside of filtering barrel (1) is passed through connecting rod (5) and is connected electromagnetic adsorption piece (6).
2. The filtering device for producing heparin sodium according to claim 1, wherein: the electromagnetic adsorption blocks (6) are two and are respectively connected with the filtering cylinder body (1) through the connecting rod (5).
3. The filtering device for producing heparin sodium according to claim 1, wherein: be equipped with filter screen (7) in filtering barrel (1), filter screen (7) are located the top of circulation feed liquor pipe (2).
4. The filtering device for producing heparin sodium according to claim 3, wherein the filtering device comprises: a ceramic membrane component (8) is arranged in the filtering cylinder body (1), and the ceramic membrane component (8) is located above the filter screen (7).
5. The filtering device for producing heparin sodium according to claim 4, wherein: the ceramic membrane module (8) is positioned below the circulating water pump (4).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022395819.6U CN213885259U (en) | 2020-10-26 | 2020-10-26 | Filter equipment is used in heparin sodium production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022395819.6U CN213885259U (en) | 2020-10-26 | 2020-10-26 | Filter equipment is used in heparin sodium production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213885259U true CN213885259U (en) | 2021-08-06 |
Family
ID=77114257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022395819.6U Active CN213885259U (en) | 2020-10-26 | 2020-10-26 | Filter equipment is used in heparin sodium production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213885259U (en) |
-
2020
- 2020-10-26 CN CN202022395819.6U patent/CN213885259U/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A filtration device for the production of heparin sodium Effective date of registration: 20231106 Granted publication date: 20210806 Pledgee: Agricultural Bank of China Limited Chongyi County Branch Pledgor: Jiangxi runquankang Biotechnology Co.,Ltd. Registration number: Y2023980064313 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |