CN213884706U - Traditional chinese medicine nasal mucosa device of dosing - Google Patents
Traditional chinese medicine nasal mucosa device of dosing Download PDFInfo
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- CN213884706U CN213884706U CN202022544655.9U CN202022544655U CN213884706U CN 213884706 U CN213884706 U CN 213884706U CN 202022544655 U CN202022544655 U CN 202022544655U CN 213884706 U CN213884706 U CN 213884706U
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Abstract
The utility model discloses a traditional chinese medicine nasal mucosa device of dosing, including installing the membrane carrier at the handle tip, the membrane carrier is including laminating portion and connecting portion, and connecting portion are hollow structure, set up the bleeder vent in a plurality of intercommunication connecting portions in the laminating portion, and the gasbag formula structure of handle for adopting elastic material to make, and the end connection of handle is in the bottom of connecting portion to be linked together with connecting portion, through using the utility model discloses dose, can avoid causing the damage to the nasal mucosa, solved nasal membrane and used inconvenient problem, be favorable to the using widely of nasal membrane.
Description
Technical Field
The utility model relates to a device of dosing, in particular to a traditional chinese medicine nasal mucosa device of dosing.
Background
Allergic rhinitis is type I hypersensitivity mediated by IgE after nasal mucosa contacts with allergen, and has participation of various immune active cells, cytokines and the like, takes nasal itching, sneezing, nasal mucosa swelling, nasal hypersecretion and the like as main clinical symptoms, seriously causes head swelling and various complications, and influences the normal life and work of patients. In recent years, with the development of social industrialization and the change of life styles of people, air pollution is increasingly serious, dust is continuously increased, and the incidence rate of allergic rhinitis is increased year by year.
From the administration route, the current clinical medicines for treating allergic rhinitis mainly comprise oral medicines and nasal medicines. Oral administration is slow to absorb, susceptible to the first pass effect of the liver, and prone to produce irritation to the gastrointestinal tract. The first-pass effect of the liver and the damage of enzymes in the gastrointestinal tract can be avoided by nasal mucosa administration, the bioavailability of the medicament is improved, and meanwhile, the nasal mucosa has large area, abundant vessels under the mucosa and rapid medicament absorption, and has the defect of easy stimulation to the nasal mucosa.
The currently clinically commonly used nasal medicines mainly comprise nasal drops, sprays, gels, ointments and the like. The nasal drop and the spray belong to a solution for nasal cavity, can be eliminated quickly due to the elimination effect of nasal mucosa cilia, have short detention time, are easy to flow into the oral cavity, and have low bioavailability of the medicine. The paste has high viscosity and long retention time, but has the defects of inaccurate administration dosage and inconvenient use. The gel has moderate viscosity, but the aqueous gel matrix of the gel is easy to dehydrate and mildew, a large amount of humectant and preservative are required to be added, the nasal mucosa is easy to be stimulated, the ciliary movement is inhibited, the absorption speed is slow, the detention time is long, and people feel uncomfortable.
The film agent can avoid the first-pass action of the liver and the stimulation to the gastrointestinal tract of oral administration, is semisolid after being dissolved, is not easy to flow to the oral cavity, has relatively long detention time in the nasal cavity, high bioavailability and accurate administration dosage. The film agent is a medicine-containing sheet, has small volume and light weight, the thickness of the film agent is generally 0.05-0.2 mm, the toughness is small, and the nasal cavity is an irregular narrow cavity gap with a narrow top and a narrow bottom and a front-back diameter larger than the left side and the right side, so the medicine administration is inconvenient. The clinical western medicine nasal membrane is very limited, such as compound ciprofloxacin nasal cavity membrane, nasal cavity anti-allergy membrane, compound ketotifen nasal membrane and the like, the prescription contains ephedrine or corticoid medicines, the dependence is easy to generate after long-term use, the side effect is large, and the ephedrine is a controlled medicine. In addition, the compound ciprofloxacin nasal cavity membrane is used for diminishing inflammation and stopping bleeding after nasal operation, and is clamped and applied to an administration part by using sterile forceps under the condition that nasal mucosa is fully exposed when the compound ciprofloxacin nasal cavity membrane is used, although the conventional membrane form is used, the compound ciprofloxacin nasal cavity membrane is not beneficial to self use of common patients. The nasal cavity anti-allergy membrane and the compound ketotifen nasal membrane are applied by dipping cotton swabs, the administration is not uniform, the administration mode is easy to cause nasal cavity mucous membrane damage, and the dosage form advantage of the membrane is not exerted. Therefore, the clinical nasal film is not popularized and used in a large range, and the administration is inconvenient probably due to the special structure of the nasal cavity, so that the nasal film is not as convenient and wide as the oral film.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a traditional chinese medicine nasal mucosa device of dosing solves among the prior art film agent and doses inconvenient problem.
The purpose of the utility model is realized like this: the utility model provides a traditional chinese medicine nasal mucosa device of dosing, is including installing the membrane carrier at the handle tip, the membrane carrier is including laminating portion and connecting portion, connecting portion are hollow structure, offer the bleeder vent in a plurality of intercommunication connecting portions in the laminating portion, the gasbag formula structure that the handle was made for adopting elastic material, and the end connection of handle is in the bottom of connecting portion to be linked together with connecting portion.
The utility model discloses the during operation presses the handle for the inside negative pressure that forms of film carrier adsorbs the film in the laminating portion of film carrier again, loosens the handle, and the film laminating is on the film carrier under the effect of negative pressure, stretches into the nasal cavity with the film carrier again, presses the handle once more, and processing film is attached on the nasal mucosa, takes adsorption equipment out, accomplishes and doses. Compared with the prior art, the beneficial effects of the utility model reside in that: through using the utility model discloses dosing, can avoid causing the damage to the nasal mucosa, solved the inconvenient problem of nasal film agent use, be favorable to using widely of nasal film agent, the device of should dosing simultaneously can also be used to the oral cavity and dose, has avoided the contact of oral cavity film agent and hand large area, comparatively safe and sanitary.
In order to make the administration more comfortable, the tops of the attaching portion and the connecting portion are all processed into arc-shaped surfaces, and the connecting portion is arranged on the back of the attaching portion.
In order to facilitate the operation, the handle part is gradually contracted from the lower part to the upper part.
Drawings
Fig. 1 is a schematic front structural view of the present invention.
Fig. 2 is a schematic view of the back structure of the present invention.
Wherein, 1 handle, 2 film agent carriers, 2a laminating part, 2b connecting part, 2c bleeder vent.
Detailed Description
As shown in fig. 1-2, a traditional chinese medicine nasal mucosa drug delivery device, including installing film agent carrier 2 at handle 1 tip, film agent carrier 2 includes laminating portion 2a and connecting portion 2b, connecting portion 2b is hollow structure, the bleeder vent 2c in a plurality of intercommunication connecting portion 2b has been seted up on laminating portion 2a, handle 1 is the gasbag formula structure of adopting elastic material to make, and the end connection of handle 1 is in connecting portion 2 b's bottom, and be linked together with connecting portion 2b, the arcwall face is all processed into at laminating portion 2a and connecting portion 2 b's top, connecting portion 2b sets up the back at laminating portion 2a, handle 1 portion is the form of contracting gradually by lower part to upper portion.
The utility model adopts medical silicon rubber as material, and is provided with a drug delivery device which is provided with a handle 1 with the length of 4cm, a film agent carrier 2 with the length and width of 1cm and the thickness of 2 mm; the top of the film agent carrier 2 is made into an arc shape, so that the administration is convenient, and the nasal cavity can be protected from being damaged during the administration.
When the device is used, SHUANGHUANGLIAN solution is obtained according to the preparation method of SHUANGHUANGLIAN oral liquid in Chinese pharmacopoeia, and is concentrated under reduced pressure to obtain SHUANGHUANGLIAN extract, and then SHUANGHUANGLIAN pellicle is prepared according to homogenization and membrane preparation method, with thickness of about 0.2mm, dried at room temperature, and cut into 1cm2A single film dosage form of (a); when allergic rhinitis occurs, a piece of the film agent is taken, the handle 1 of the drug delivery device is extruded, the internal gas is exhausted through the air holes 2c, the film agent carrier 2 is aligned with the film agent, the handle 1 is slowly loosened until the film agent is adsorbed on the carrier 2, the film agent is placed in a nasal cavity, the film agent is attached to the nasal septum, and then the device is taken out.
The utility model discloses a theory of operation does:
the utility model relates to an apparatus utilizes the atmospheric pressure difference principle, and handle 1 through the extrusion device of dosing is with inside gaseous evacuation, and pressure reduces, when loosening handle 1 slowly, has gaseous entering through bleeder vent 2c, and pressure increases gradually, but the inside pressure this moment still is less than atmospheric pressure, because the quality of film agent is lighter, will be adsorbed on carrier 2, when extrudeing handle 1 once more with external force, the film agent will drop from carrier 2 to attached on the nasal mucosa.
The present invention is not limited to the above embodiments, and based on the technical solutions disclosed in the present invention, those skilled in the art can make some replacements and transformations for some technical features without creative labor according to the disclosed technical contents, and these replacements and transformations are all within the protection scope of the present invention.
Claims (3)
1. The utility model provides a traditional chinese medicine nasal mucosa device of dosing which characterized in that, is including installing the membrane carrier at the handle tip, the membrane carrier is including laminating portion and connecting portion, connecting portion are hollow structure, offer the bleeder vent in a plurality of intercommunication connecting portions in the laminating portion, the gasbag formula structure that the handle was made for adopting elastic material, and the end connection of handle is in the bottom of connecting portion to be linked together with connecting portion.
2. The nasal mucosa drug delivery device for traditional Chinese medicine according to claim 1, wherein the tops of the joint part and the connecting part are both processed into arc-shaped surfaces, and the connecting part is arranged on the back of the joint part.
3. The nasal mucosa administration device for traditional Chinese medicine according to claim 1 or 2, wherein the handle portion is gradually contracted from the lower portion to the upper portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022544655.9U CN213884706U (en) | 2020-11-06 | 2020-11-06 | Traditional chinese medicine nasal mucosa device of dosing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022544655.9U CN213884706U (en) | 2020-11-06 | 2020-11-06 | Traditional chinese medicine nasal mucosa device of dosing |
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| Publication Number | Publication Date |
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| CN213884706U true CN213884706U (en) | 2021-08-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202022544655.9U Active CN213884706U (en) | 2020-11-06 | 2020-11-06 | Traditional chinese medicine nasal mucosa device of dosing |
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| CN (1) | CN213884706U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI773580B (en) * | 2021-11-10 | 2022-08-01 | 新旺生醫股份有限公司 | Pharmaceuticals carrier and use method thereof |
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2020
- 2020-11-06 CN CN202022544655.9U patent/CN213884706U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI773580B (en) * | 2021-11-10 | 2022-08-01 | 新旺生醫股份有限公司 | Pharmaceuticals carrier and use method thereof |
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