CN213875636U - Flow cell method medicine dissolving out device - Google Patents

Flow cell method medicine dissolving out device Download PDF

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Publication number
CN213875636U
CN213875636U CN202021882779.1U CN202021882779U CN213875636U CN 213875636 U CN213875636 U CN 213875636U CN 202021882779 U CN202021882779 U CN 202021882779U CN 213875636 U CN213875636 U CN 213875636U
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China
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water area
upper cover
flow cell
water
fixing
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CN202021882779.1U
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Chinese (zh)
Inventor
李定中
姚鹏志
雷浩
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Lugen Shanghai Life Technology Co ltd
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Lugen Shanghai International Trade Co ltd
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Abstract

A medicine dissolving device adopting a flow cell method is characterized in that side fixing blocks are arranged at two ends of a liquid collecting tank; the cushion blocks are arranged at the bottom sides of the two ends of the liquid collecting tank; the liquid tank top plate is arranged on the top surface of the liquid collecting tank; the water area base is fixed on the top surface of the liquid tank top plate; the water area upper cover is arranged on the top surface of the water area base; knob fixing cylinders are arranged on two sides of the top surface of the water area upper cover, and the knobs are connected with the knob fixing cylinders in an inserting manner; the support rods are arranged on two sides of the outer wall of the water area base; the glass tube is sleeved and fixed on the water area base and the water area upper cover; the flow cell is embedded into the upper cover fixing hole; the side fixing plates are arranged on two sides of the liquid tank top plate; the shade connecting block is arranged on the top side of the side fixing plate; the two ends of the shade fixing rod are rotatably arranged through the rotating shaft and the shade connecting blocks on the two sides; the flow cell back plate is arranged on one side of the flow cell. The utility model discloses the inside and outside that makes the flow-through cell is formed with the passageway that good menstruum flows and circulating water flows respectively, carries out the heat transfer through waters and menstruum and realizes accurate accuse temperature.

Description

Flow cell method medicine dissolving out device
Technical Field
The utility model relates to the technical field of medical experimental equipment application, in particular to a drug dissolution device by a flow cell method.
Background
As a novel dissolution concentration checking method, the flow cell method mainly depends on flowing solvent to continuously flush the preparation, can well simulate the in vivo circulation of the medicine in a human body, and selects proper cell body accessories to be suitable for tablets, capsules, patches, microspheres, suppositories, suspensions, stents, implants, liposomes and the like.
In the process of carrying out a drug dissolution test by a flow cell method, a solvent is used for carrying out a flow scouring action on the drug in the flow cell, the drug and the solvent are subjected to a dissolution process, the solvent after the drug is dissolved out is circulated through a circulating system, and sampling is carried out through a sampling system. When a medicine is dissolved in the flow cell, in order to enable the medicine dissolution process to be closer to the actual dissolution environment of the medicine in a human body, the flow cell needs to be subjected to heat preservation treatment, the body temperature of the human body is simulated, the dissolution temperature of a solvent is controlled to be 37 ℃, a device capable of controlling the temperature of the flow cell is needed, the flow cell can be subjected to high-efficiency heat preservation treatment, and the flow cell and the device can be quickly assembled.
SUMMERY OF THE UTILITY MODEL
In order to solve the existing problems, the utility model discloses a device for dissolving out drugs by a flow cell method, which comprises the following specific technical scheme: a medicine dissolving device adopting a flow cell method comprises a side fixing block, a liquid collecting tank, a liquid discharge pipe, a cushion block, a liquid tank top plate, a water area base, a water area upper cover, a knob, a supporting rod, a glass pipe, a flow cell, a side fixing plate, a mask connecting block, a mask fixing rod, a flow cell mask and a flow cell back plate;
the side fixing blocks are arranged at two ends of the liquid collecting tank and are assembled with the liquid collecting tank through fasteners; the cushion blocks are arranged at the bottom sides of the two ends of the liquid collecting tank and are assembled with the side fixing blocks through fasteners; a liquid collecting groove side hole is formed in the side wall of the liquid collecting groove, a liquid collecting groove bottom hole is formed in the bottom end of the liquid collecting groove, and one end of the liquid discharge pipe is assembled and communicated with the liquid collecting groove bottom hole; the liquid tank top plate is arranged on the top surface of the liquid collecting tank and is assembled with the liquid collecting tank through a fastener; the water area base is fixed on the top surface of the liquid tank top plate and arranged in a transverse array, a solvent inlet is formed in the center of the water area base, one end of the solvent inlet is connected with a solvent inlet connector, a water area water inlet is formed in one side of the water area base, and the water area water inlet is connected with a water area water inlet connector; the water area upper cover is arranged on the top surface of the water area base, an upper cover fixing hole is formed in the center of the water area upper cover, a water area water outlet is formed in one side of the water area upper cover, and the water area water outlet is connected with a water area water outlet connector; knob fixing cylinders are arranged on two sides of the top surface of the water area upper cover, and the knobs are connected with the knob fixing cylinders in an inserting mode; the supporting rods are arranged on two sides of the outer wall of the water area base, the bottom ends of the supporting rods are vertically fixed with the liquid tank top plate, and the top ends of the supporting rods are vertically fixed with the bottom surface of the water area upper cover; the glass tube is sleeved and fixed on the water area base and the water area upper cover; the flow cell is embedded into the upper cover fixing hole to realize the limiting and fixing of the flow cell and the upper cover of the water area, and the bottom end of the flow cell is spliced and communicated with the solvent inlet connector; the side fixing plates are arranged on two sides of the liquid tank top plate and are symmetrically arranged, and the bottom end of each side fixing plate is fixed with the liquid tank top plate through a fastening piece; the shade connecting block is arranged on the top side of the side fixing plate on each side and is assembled with the side fixing plate through a fastener; the two ends of the shade fixing rod are rotatably arranged with the shade connecting blocks on the two sides through a rotating shaft; the flow cell shade is attached to the side wall of the shade connecting block, and the flow cell shade is assembled with the shade fixing rod through a fastener; the flow cell back plate is arranged on one side of the flow cell, and the two sides of the flow cell back plate are assembled with the side fixing plates through fasteners.
Furthermore, the length of the cushion block is longer than the width of the liquid collecting groove, and two ends of the cushion block extend out of two sides of the bottom surface of the liquid collecting groove; the bottom surface of each side cushion block is provided with a rubber foot, and the rubber feet are fixed with the two ends of the bottom surface of each cushion block through insertion.
Furthermore, the number of the bottom holes of the liquid collecting tank arranged in the liquid collecting tank is two, and each liquid discharge pipe is arranged in an alignment mode with each bottom hole of the liquid collecting tank; the end part of the liquid discharge pipe is in a flange shape, one end of the liquid discharge pipe extends into the bottom hole of the liquid collecting tank, the flange of the liquid discharge pipe is attached to the inner bottom surface of the liquid collecting tank, and the liquid discharge pipe is matched with the liquid collecting tank through a fastener, so that the liquid discharge pipe is vertically communicated with the liquid collecting tank.
Furthermore, the top surface of the water area base is of a layered structure to form a base layered platform, a base sealing ring is embedded in the circumferential direction of the side wall of the base layered platform, the bottom end of the glass tube is sleeved on the outer wall of the base layered platform to realize insertion and fixation, and the glass tube and the water area base are sealed through the base sealing ring; the water inlet of the water area is communicated with the top surface of the base layer platform.
Furthermore, the solvent inlet joint is arranged at the center of the top surface of the water area base, and the solvent inlet joint and the water area base are vertically arranged.
Furthermore, the water area upper cover is of a square structure; the center of the bottom surface of the water area upper cover is of a layered platform-shaped structure to form an upper cover layer platform, an upper cover sealing ring is embedded in the circumferential direction of the side wall of the upper cover layer platform, the top end of the glass tube is sleeved on the outer wall of the upper cover layer platform to realize insertion and fixation, and the glass tube and the water area upper cover are sealed through the upper cover sealing ring; the water area water outlet is communicated with the bottom surface of the upper cover layer platform.
Furthermore, the solvent inlet joint, the water inlet joint and the water outlet joint are luer joints.
Furthermore, the bracing piece with the waters upper cover is the slant setting, the fixed section of thick bamboo of knob with the waters upper cover is the slant setting, just the bracing piece with the fixed section of thick bamboo of knob is the cross setting.
Furthermore, the bottom end of the knob extends into the knob fixing cylinder correspondingly, and the knob fixing cylinder are fixed in a threaded manner; each side wall of the knob is provided with a knob fixing sheet, and the knob fixing sheets are perpendicular to the knob. The structure principle of the utility model is that:
when the device is used, the medicine is supported and fixed in the flow cell through the medicine supporting structure, the flow cell is inserted in the upper cover fixing hole, the bottom end of the flow cell is inserted and fixed with the solvent inlet connector, and then the knob is rotated to enable the knob fixing piece to be buckled at the end part of the flow cell; the menstruum flows through the menstruum inlet joint through the menstruum inlet and enters the circulation, and after the menstruum and the medicine are washed and dissolved out, the menstruum is discharged from the top end of the flow cell; circulating water flows through the water inlet of the water area through the water inlet joint and enters the glass tube, the circulating water exchanges heat and preserves heat for the side wall of the flow-through pool, after the circulating water fills the glass tube, the circulating water flows through the water outlet joint of the water area through the water outlet of the water area and is discharged, and the circulating water is connected with the side hole of the liquid collecting tank through a pipeline and is discharged from the bottom hole of the liquid collecting tank.
The utility model has the advantages that:
the utility model discloses carry out the design of waters heat preservation to the flow-through cell structure department of flow-through cell method, through inserting the flow-through cell glass intraductal fixedly, and carry out full circulating water in the glass intraductal circulation, make the inside and outside of flow-through cell respectively form the passageway that good menstruum flows and circulating water flows, form the waters in the outside of flow-through cell through the circulating water and wrap up the heat transfer, heat transfer process efficiency is high-efficient, make the dissolution process of medicine and menstruum in the flow-through cell at invariable settlement temperature, realized the accurate accuse temperature to medicine dissolution test;
the overall structure of device is compact, and the flow-through cell can carry out quick grafting intercommunication with glass tube structure, can carry out quick pressfitting through the knob structure and fix, forms good seal structure, and the circulating water has smooth and easy circulating water circulation way simultaneously, and device structural design is exquisite.
Drawings
Fig. 1 is a schematic view of the overall appearance structure of the present invention.
Fig. 2 is a schematic view of the overall internal structure of the present invention.
Figure 3 is an overall elevation view of the present invention.
Fig. 4 is an overall front sectional view of the present invention.
Figure 5 is a cross-sectional view of a single glass tube structure of the present invention.
List of reference numerals:
a side fixing block 1;
a liquid collecting tank 2;
a side hole 2-1 of the collecting tank and a bottom hole 2-2 of the collecting tank;
a drain pipe 3;
a cushion block 4;
4-1 parts of rubber feet;
a liquid tank top plate 5;
a water area base 6;
solvent inlet 6-1, solvent inlet joint 6-2, water inlet 6-3, water inlet joint 6-4, base layer 6-5, and base sealing ring 6-6;
a water area upper cover 7;
an upper cover fixing hole 7-1, a water area water outlet 7-2, a water area water outlet joint 7-3, a knob fixing cylinder 7-4, an upper cover layer table 7-5 and an upper cover sealing ring 7-6;
a knob 8;
8-1 of a knob fixing piece;
a support bar 9;
a glass tube 10;
a flow cell 11;
a side fixing plate 12;
a mask connecting block 13;
a shade fixing rod 14;
a flow cell mask 15;
a flow cell back plate 16.
Detailed Description
For making the technical scheme of the utility model clear more clearly and definitely, it is right to combine the drawing below the utility model discloses further describe, any is right the utility model discloses technical scheme's technical characteristic carries out the scheme that equivalent replacement and conventional reasoning reachs and all falls into the utility model discloses protection scope. The fixed connection, the fixed arrangement and the fixed structure mentioned in the embodiment are known technologies known to those skilled in the art, such as gluing, welding, screwing, bolt-nut connection, riveting and the like.
As can be seen by combining the attached drawings, the medicine dissolving device adopting the flow cell method comprises a side fixing block 1, a liquid collecting groove 2, a liquid discharge pipe 3, a cushion block 4, a liquid groove top plate 5, a water area base 6, a water area upper cover 7, a knob 8, a support rod 9, a glass tube 10, a flow cell 11, a side fixing plate 12, a shade connecting block 13, a shade fixing rod 14, a flow cell shade 15 and a flow cell back plate 16;
the side fixing blocks 1 are arranged at two ends of the liquid collecting tank 2, and the side fixing blocks 1 are assembled with the liquid collecting tank 2 through fasteners; the cushion blocks 4 are arranged at the bottom sides of the two ends of the liquid collecting tank 2, and the cushion blocks 4 are assembled with the side fixing blocks 1 through fasteners; a liquid collecting groove side hole 2-1 is formed in the side wall of the liquid collecting groove 2, a liquid collecting groove bottom hole 2-2 is formed in the bottom end of the liquid collecting groove 2, and one end of the liquid discharge pipe 3 is assembled and communicated with the liquid collecting groove bottom hole 2-2; the liquid tank top plate 5 is arranged on the top surface of the liquid collecting tank 2, and the liquid tank top plate 5 is assembled with the liquid collecting tank 2 through a fastener; the water area base 6 is fixed on the top surface of the liquid tank top plate 5 and is arranged in a transverse array, a solvent inlet is formed in the center of the water area base 6, one end of the solvent inlet is connected with a solvent inlet connector 6-2, a water area water inlet 6-3 is formed in one side of the water area base 6, and the water area water inlet 6-3 is connected with a water area water inlet connector 6-4; the water area upper cover 7 is arranged on the top surface of the water area base 6, an upper cover fixing hole 7-1 is formed in the center of the water area upper cover 7, a water area water outlet 7-2 is formed in one side of the water area upper cover 7, and the water area water outlet 7-2 is connected with a water area water outlet connector 7-3; knob fixing cylinders 7-4 are arranged on two sides of the top surface of the water area upper cover 7, and the knob 8 is connected with the knob fixing cylinders 7-4 in an inserted manner; the supporting rods 9 are arranged on two sides of the outer wall of the water area base 6, the bottom ends of the supporting rods 9 are vertically fixed with the liquid tank top plate 5, and the top ends of the supporting rods 9 are vertically fixed with the bottom surface of the water area upper cover 7; the glass tube 10 is fixedly sleeved on the water area base 6 and the water area upper cover 7; the flow cell 11 is embedded into the upper cover fixing hole 7-1, so that the flow cell 11 and the water area upper cover 7 are limited and fixed, and the bottom end of the flow cell 11 is in inserted connection with the solvent inlet connector 6-2; the side fixing plates 12 are arranged at two sides of the liquid tank top plate 5 symmetrically, and the bottom end of each side fixing plate 12 is fixed with the liquid tank top plate 5 through a fastening piece; the shade connecting block 13 is arranged at the top side of the side fixing plate 12 at each side, and is assembled with the side fixing plate 12 through a fastener; the two ends of the shade fixing rod 14 are rotatably arranged with the shade connecting blocks 13 at the two sides through a rotating shaft; the flow cell mask 15 is attached to the side wall of the mask connecting block 13, and the flow cell mask 15 is assembled with the mask fixing rod 14 through a fastener; the flow cell back plate 16 is arranged on one side of the flow cell 11, and two sides of the flow cell back plate 16 are assembled with the side fixing plates 12 on two sides through fasteners.
Further, the length of the cushion block 4 is longer than the width of the liquid collecting groove 2, and two ends of the cushion block 4 extend out of two sides of the bottom surface of the liquid collecting groove 2; the bottom surface of each cushion block 4 is provided with a rubber foot 4-1, and the rubber feet 4-1 are fixed with the two ends of the bottom surface of each cushion block 4 through insertion.
Furthermore, the number of the liquid collecting groove bottom holes 2-2 arranged in the liquid collecting groove 2 is two, and each liquid discharge pipe 3 and each liquid collecting groove bottom hole 2-2 are arranged in an alignment mode; the end part of the liquid discharge pipe 3 is in a flange shape, one end of the liquid discharge pipe 3 extends into the bottom hole 2-2 of the liquid collecting tank, the flange of the liquid discharge pipe 3 is attached to the inner bottom surface of the liquid collecting tank 2, the liquid discharge pipe 3 is matched with the liquid collecting tank 2 through a fastener, and the liquid discharge pipe 3 is vertically communicated with the liquid collecting tank 2.
Further, the top surface of the water area base 6 is of a layered structure to form a base layer 6-5, a base sealing ring 6-6 is embedded in the circumferential direction of the side wall of the base layer 6-5, the bottom end of the glass tube 10 is sleeved on the outer wall of the base layer 6-5 to realize insertion and fixation, and the glass tube 10 and the water area base 6 are sealed through the base sealing ring 6-6; the water inlet 6-3 of the water area is communicated with the top surface of the base layer 6-5.
Further, the solvent inlet connector 6-2 is arranged at the center of the top surface of the water area base 6, and the solvent inlet connector 6-2 is perpendicular to the water area base 6.
Further, the water area upper cover 7 is of a square structure; the center of the bottom surface of the water area upper cover 7 is of a layered platform-shaped structure to form an upper cover layer platform 7-5, an upper cover sealing ring 7-6 is embedded in the circumferential direction of the side wall of the upper cover layer platform 7-5, the top end of the glass tube 10 is sleeved on the outer wall of the upper cover layer platform 7-5 to realize insertion and fixation, and the glass tube 10 and the water area upper cover 7 are sealed through the upper cover sealing ring 7-6; the water outlet 7-2 of the water area is communicated with the bottom surface of the upper cover layer 7-5.
Furthermore, the solvent inlet joint 6-2, the water area water inlet joint 6-4 and the water area water outlet joint 7-3 are all luer joints.
Furthermore, the supporting rod 9 and the water area upper cover 7 are obliquely arranged, the knob fixing cylinder 7-4 and the water area upper cover 7 are obliquely arranged, and the supporting rod 9 and the knob fixing cylinder 7-4 are in a cross shape.
Further, the bottom end of the knob 8 extends into the knob fixing cylinder 7-4 correspondingly, and the knob 8 and the knob fixing cylinder 7-4 are fixed in a threaded manner; the side wall of each knob 8 is provided with a knob fixing plate 8-1, and the knob fixing plates 8-1 are perpendicular to the knobs 8.
The structure principle of the utility model is that:
when the device is used, the medicine is supported and fixed in the flow cell through the medicine supporting structure, the flow cell is inserted in the upper cover fixing hole, the bottom end of the flow cell is inserted and fixed with the solvent inlet connector, and then the knob is rotated to enable the knob fixing piece to be buckled at the end part of the flow cell; the menstruum flows through the menstruum inlet joint through the menstruum inlet and enters the circulation, and after the menstruum and the medicine are washed and dissolved out, the menstruum is discharged from the top end of the flow cell; circulating water flows through the water inlet of the water area through the water inlet joint and enters the glass tube, the circulating water exchanges heat and preserves heat for the side wall of the flow-through pool, after the circulating water fills the glass tube, the circulating water flows through the water outlet joint of the water area through the water outlet of the water area and is discharged, and the circulating water is connected with the side hole of the liquid collecting tank through a pipeline and is discharged from the bottom hole of the liquid collecting tank.
The utility model has the advantages that:
the utility model discloses carry out the design of waters heat preservation to the flow-through cell structure department of flow-through cell method, through inserting the flow-through cell glass intraductal fixedly, and carry out full circulating water in the glass intraductal circulation, make the inside and outside of flow-through cell respectively form the passageway that good menstruum flows and circulating water flows, form the waters in the outside of flow-through cell through the circulating water and wrap up the heat transfer, heat transfer process efficiency is high-efficient, make the dissolution process of medicine and menstruum in the flow-through cell at invariable settlement temperature, realized the accurate accuse temperature to medicine dissolution test;
the overall structure of device is compact, and the flow-through cell can carry out quick grafting intercommunication with glass tube structure, can carry out quick pressfitting through the knob structure and fix, forms good seal structure, and the circulating water has smooth and easy circulating water circulation way simultaneously, and device structural design is exquisite.

Claims (9)

1. A medicine dissolution device by a flow cell method is characterized by comprising a side fixing block (1), a liquid collecting tank (2), a liquid discharge pipe (3), a cushion block (4), a liquid tank top plate (5), a water area base (6), a water area upper cover (7), a knob (8), a support rod (9), a glass pipe (10), a flow cell (11), a side fixing plate (12), a shade connecting block (13), a shade fixing rod (14), a flow cell shade (15) and a flow cell back plate (16);
the side fixing blocks (1) are arranged at two ends of the liquid collecting tank (2), and the side fixing blocks (1) are assembled with the liquid collecting tank (2) through fasteners; the cushion blocks (4) are arranged at the bottom sides of the two ends of the liquid collecting tank (2), and the cushion blocks (4) are assembled with the side fixing blocks (1) through fasteners; a liquid collecting groove side hole (2-1) is formed in the side wall of the liquid collecting groove (2), a liquid collecting groove bottom hole (2-2) is formed in the bottom end of the liquid collecting groove (2), and one end of the liquid discharge pipe (3) is assembled and communicated with the liquid collecting groove bottom hole (2-2); the liquid tank top plate (5) is arranged on the top surface of the liquid collecting tank (2), and the liquid tank top plate (5) is assembled with the liquid collecting tank (2) through a fastener; the water area base (6) is fixed on the top surface of the liquid tank top plate (5) and is arranged in a transverse array, a solvent inlet is formed in the center of the water area base (6), one end of the solvent inlet is connected with a solvent inlet connector (6-2), a water area water inlet (6-3) is formed in one side of the water area base (6), and the water area water inlet (6-3) is connected with a water area water inlet connector (6-4); the water area upper cover (7) is arranged on the top surface of the water area base (6), an upper cover fixing hole (7-1) is formed in the center of the water area upper cover (7), a water area water outlet (7-2) is formed in one side of the water area upper cover (7), and the water area water outlet (7-2) is connected with a water area water outlet connector (7-3); knob fixing cylinders (7-4) are arranged on two sides of the top surface of the water area upper cover (7), and the knob (8) is connected with the knob fixing cylinders (7-4) in an inserting mode; the supporting rods (9) are arranged on two sides of the outer wall of the water area base (6), the bottom ends of the supporting rods (9) are vertically fixed with the liquid tank top plate (5), and the top ends of the supporting rods (9) are vertically fixed with the bottom surface of the water area upper cover (7); the glass tube (10) is fixedly sleeved on the water area base (6) and the water area upper cover (7); the flow cell (11) is embedded into the upper cover fixing hole (7-1) to realize the limiting and fixing of the flow cell (11) and the water area upper cover (7), and the bottom end of the flow cell (11) is connected with the solvent inlet connector (6-2) in an inserting manner; the side fixing plates (12) are arranged on two sides of the liquid tank top plate (5) symmetrically, and the bottom end of each side fixing plate (12) is fixed with the liquid tank top plate (5) through a fastener; the shade connecting block (13) is arranged on the top side of the side fixing plate (12) on each side, and is assembled with the side fixing plate (12) through a fastener; two ends of the shade fixing rod (14) are rotatably arranged with the shade connecting blocks (13) at two sides through a rotating shaft; the flow cell shade (15) is attached to the side wall of the shade connecting block (13), and the flow cell shade (15) is assembled with the shade fixing rod (14) through a fastener; the flow cell back plate (16) is arranged on one side of the flow cell (11), and the two sides of the flow cell back plate (16) are assembled with the side fixing plates (12) on the two sides through fasteners.
2. The flow cell drug dissolution device according to claim 1, wherein the length of the cushion block (4) is longer than the width of the liquid collection tank (2), and both ends of the cushion block (4) extend out of both sides of the bottom surface of the liquid collection tank (2); rubber feet (4-1) are arranged on the bottom surface of each cushion block (4), and the rubber feet (4-1) are fixed with the two ends of the bottom surface of each cushion block (4) in an inserting mode.
3. A flow cell drug dissolution device according to claim 1, wherein the number of the bottom holes (2-2) of the sump (2) is two, and each of the drainage pipes (3) is aligned with each of the bottom holes (2-2); the end part of the liquid discharge pipe (3) is in a flange shape, one end of the liquid discharge pipe (3) extends into the bottom hole (2-2) of the liquid collecting tank, the flange of the liquid discharge pipe (3) is attached to the inner bottom surface of the liquid collecting tank (2), the liquid discharge pipe (3) is matched with the liquid collecting tank (2) through a fastener, and the liquid discharge pipe (3) and the liquid collecting tank (2) are vertically communicated.
4. The flow cell method drug dissolution device according to claim 1, wherein the top surface of the water area base (6) is a layered platform structure to form a base layered platform (6-5), a base sealing ring (6-6) is embedded in the circumferential direction of the side wall of the base layered platform (6-5), the bottom end of the glass tube (10) is sleeved on the outer wall of the base layered platform (6-5) to realize insertion fixation, and the glass tube (10) and the water area base (6) are sealed by the base sealing ring (6-6); the water inlet (6-3) of the water area is communicated with the top surface of the base layer table (6-5).
5. The flow cell-based drug dissolution apparatus according to claim 1, wherein the solvent inlet connector (6-2) is disposed at the center of the top surface of the water base (6), and the solvent inlet connector (6-2) is perpendicular to the water base (6).
6. The flow cell drug dissolution apparatus according to claim 1, wherein the water cover (7) has a square structure; the center of the bottom surface of the water area upper cover (7) is of a layered platform-shaped structure to form an upper cover layer platform (7-5), an upper cover sealing ring (7-6) is embedded in the circumferential direction of the side wall of the upper cover layer platform (7-5), the top end of the glass tube (10) is sleeved on the outer wall of the upper cover layer platform (7-5) to realize insertion and fixation, and the glass tube (10) and the water area upper cover (7) are sealed through the upper cover sealing ring (7-6); the water outlet (7-2) of the water area is communicated with the bottom surface of the upper cover layer platform (7-5).
7. The device for drug dissolution by the flow cell method according to claim 1, wherein the solvent inlet connector (6-2), the water inlet connector (6-4) and the water outlet connector (7-3) are luer connectors.
8. The device for drug dissolution by the flow cell method according to claim 1, wherein the support rod (9) is obliquely disposed to the water area upper cover (7), the knob fixing cylinder (7-4) is obliquely disposed to the water area upper cover (7), and the support rod (9) is cross-shaped to the knob fixing cylinder (7-4).
9. The flow cell method drug dissolution device according to claim 1, wherein the bottom end of the knob (8) extends into the corresponding knob fixing cylinder (7-4), and the knob (8) is fixed with the knob fixing cylinder (7-4) in a threaded manner; the side wall of each knob (8) is provided with a knob fixing piece (8-1), and the knob fixing pieces (8-1) and the knobs (8) are arranged vertically.
CN202021882779.1U 2020-09-02 2020-09-02 Flow cell method medicine dissolving out device Active CN213875636U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021882779.1U CN213875636U (en) 2020-09-02 2020-09-02 Flow cell method medicine dissolving out device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021882779.1U CN213875636U (en) 2020-09-02 2020-09-02 Flow cell method medicine dissolving out device

Publications (1)

Publication Number Publication Date
CN213875636U true CN213875636U (en) 2021-08-03

Family

ID=77047628

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202021882779.1U Active CN213875636U (en) 2020-09-02 2020-09-02 Flow cell method medicine dissolving out device

Country Status (1)

Country Link
CN (1) CN213875636U (en)

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