CN213866156U - Nucleic acid extraction instrument - Google Patents

Abstract

The utility model discloses a nucleic acid extractor, which comprises a nucleic acid extractor main body, a chassis component, a turntable component, an extraction motion component and an electric control component; the nucleic acid extractor main body consists of a chassis assembly, a turntable assembly, an extraction motion assembly and an electric control assembly, wherein the chassis assembly comprises an installation base, an upright post supporting assembly and a hollow rotating platform, the chassis assembly is fixed and leveled by the upright post supporting assembly, and the turntable assembly is supported by the chassis assembly by the hollow rotating platform; the utility model discloses a carousel formula's nucleic acid extraction appearance, motion mechanism part is put in the machine mid portion moreover to can effectual reduction complete machine volume, consequently can effectively practice thrift the laboratory space, the utility model discloses the well bottom subassembly, draw the motion subassembly and all have leveling mechanism, guarantee that nucleic acid extraction process is even, heating module can dismantle moreover, changes the heating module of matching according to different deep hole boards, promotes and draws the effect.

Description

Nucleic acid extraction instrument

Technical Field

The utility model relates to a nucleic acid extraction technical field specifically is a nucleic acid extraction appearance.

Background

The nucleic acid extractor is an instrument which automatically finishes the work of extracting the nucleic acid of a sample by using a matched nucleic acid extracting reagent. The method is widely applied to various fields of disease control center, clinical disease diagnosis, blood transfusion safety, forensic medicine identification, environmental microorganism detection, food safety detection, animal husbandry, molecular biology research and the like.

The existing nucleic acid extractor has the following defects:

1. the existing nucleic acid extractor has dispersed electrical elements, which causes difficult maintenance and repair.

2. The sample moving mode of the existing nucleic acid extraction instrument is mostly linear guide rail type moving, the volume is large, and the laboratory space is wasted.

3. The existing nucleic acid extractor is not provided with a leveling mechanism, the relative position cannot be adjusted, and a heating module cannot be disassembled, so that the existing problem is solved by the nucleic acid extractor.

Disclosure of Invention

An object of the present invention is to provide a nucleic acid extracting apparatus to solve the problems in the background art.

In order to achieve the above object, the utility model provides a following technical scheme: a nucleic acid extractor comprises a nucleic acid extractor main body, a chassis component, a turntable component, an extraction motion component and an electric control component; the nucleic acid extraction instrument main body comprises a chassis component, a turntable component, an extraction motion component and an electric control component, wherein the chassis component comprises an installation base, a stand column supporting component and a hollow rotary platform, the chassis component is fixed and leveled by the stand column supporting component and supports the turntable component by the hollow rotary platform, four corners at the bottom of the stand column supporting component are respectively provided with a stand column fixing hole and a first leveling hole, the turntable component comprises a turntable main body, a deep hole plate fixing frame and a heating module component, the turntable component is fixed on the hollow rotary platform by a turntable transition plate, one circle of the surface of the turntable transition plate is provided with eight groups of equidistant second leveling holes and disc fixing holes, the center position of the surface of the turntable transition plate is provided with four groups of equidistant platform fixing holes, one circle of the top of the turntable main body is provided with eight groups of equidistant deep hole plate fixing frames by a turntable disk position, and wherein the fixed frame internally mounted of two sets of deep hole boards adjacent has heating module subassembly, draw the motion subassembly including shock dynamo, Z axle motor, bar magnet frame subassembly, bar magnet cover frame subassembly, fender liquid board and driving motor, and draw the top position department of motion subassembly one side and install shock dynamo, it is equipped with Z axle motor to draw one side top that the shock dynamo was kept away from to the motion subassembly, the front side that draws the motion subassembly is equipped with bar magnet cover frame subassembly, it is equipped with bar magnet frame subassembly to draw the top that the motion subassembly front side is located bar cover frame subassembly, driving motor is installed with the junction of drawing the motion subassembly to keep off the liquid board, the front end department of automatically controlled subassembly bottom install with light and sterilamp.

Preferably, a turntable mark is arranged at a position, corresponding to the deep hole plate fixing frame, on the surface of the turntable main body, and a heating module mark is arranged at a position, corresponding to the heating module assembly, on the surface of the turntable main body.

Preferably, the inside of the fixed frame of deep hole board is equipped with the deep hole board direction, the front end of the fixed frame of deep hole board is equipped with the deep hole board visual window.

Preferably, the heating module assembly comprises a heating module cover, a heating sheet, a temperature controller, a heat insulation plate and a heating base, the heating sheet is embedded into the top of the heating module cover, the temperature controller is arranged on one side of the heating sheet, the heat insulation plate is installed at the top of the heating module cover, and the heating base is embedded into the heat insulation plate.

Preferably, the magnetic rod frame assembly comprises a magnetic rod mounting plate, lightening holes and a magnetic rod assembly, the lightening holes are formed in the surface of the magnetic rod mounting plate, and the magnetic rod assembly is arranged at the bottom of the magnetic rod mounting plate.

Preferably, bar magnet cover frame subassembly includes bar magnet lagging, bar magnet cover left side board, bar magnet cover right side board and location pearl, and has bar magnet lagging between bar magnet cover left side board and the bar magnet cover right side board through location pearl fixed mounting.

Preferably, the central position department of automatically controlled subassembly top rear side is equipped with the main control board, one side at automatically controlled subassembly top is equipped with motor drive, one side that motor drive was kept away from at automatically controlled subassembly top is equipped with switching power supply.

Preferably, the positive top of nucleic acid extraction appearance main part is equipped with the touch-sensitive screen, the rear side of nucleic acid extraction appearance main part is equipped with the backshell, the positive bottom of nucleic acid extraction appearance main part is equipped with the switch door, and the surface of switch door is equipped with the observation window.

Preferably, the electric control assembly is electrically connected with the touch screen through a wire, the switch power supply is electrically connected with the illuminating lamp, the sterilizing lamp and the temperature controller through wires, the motor is driven to be electrically connected with the vibration motor and the Z-axis motor through wires, and the temperature controller is electrically connected with the heating plate through wires.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses well complete machine modularized design, wherein electric elements concentrates and places, after pulling down the backshell, can carry out routine maintenance and after-sales repair, labour saving and time saving and convenience, and electric elements dispersion leads to maintaining and after-sales repair very trouble condition emergence in the effectual traditional nucleic acid of avoiding draws the appearance.

2. The utility model discloses a carousel formula's nucleic acid extraction appearance, motion mechanism part is put in the machine mid portion moreover to can effectual reduction complete machine volume, consequently can effectively practice thrift the laboratory space.

3. The utility model discloses well bottom disc subassembly, extraction motion subassembly all have leveling mechanism, guarantee that the nucleic acid extraction process is even, and heating module can dismantle moreover, changes the heating module of matching according to different deep hole boards, promotes and draws the effect.

Drawings

Fig. 1 is a perspective view of the present invention;

FIG. 2 is a disassembled perspective view of the rear shell of the present invention;

FIG. 3 is a perspective view of the chassis assembly, turntable assembly and extraction motion assembly of the present invention;

FIG. 4 is a top perspective view of the chassis assembly, turntable assembly and extraction motion assembly of the present invention;

FIG. 5 is a perspective view of the chassis assembly of FIG. 3 in accordance with the present invention;

fig. 6 is a perspective view of the pillar brace assembly of fig. 5 according to the present invention;

fig. 7 is a top perspective view of the turntable assembly of fig. 3 in accordance with the present invention;

fig. 8 is a perspective view of the transition plate of fig. 7 according to the present invention;

fig. 9 is a perspective view of the fixing frame for the medium-length hole plate shown in fig. 7 according to the present invention;

fig. 10 is an exploded view of the heating module assembly of fig. 7 in accordance with the present invention;

fig. 11 is a perspective view of the extraction motion assembly of fig. 3 according to the present invention;

fig. 12 is a top view of the extraction motion assembly of fig. 3 in accordance with the present invention;

fig. 13 is an enlarged schematic view of the magnetic rod rack assembly of fig. 11 in accordance with the present invention;

fig. 14 is an exploded view of the rod holder assembly of fig. 11 in accordance with the present invention;

fig. 15 is a perspective view of the electric control assembly in fig. 2 according to the present invention.

In the figure: 1. a nucleic acid extractor body; 2. a chassis assembly; 201. installing a base; 202. a column support assembly; 203. a hollow rotating platform; 204. a column fixing hole; 205. a first leveling hole; 3. a turntable assembly; 301. a turntable main body; 302. a deep hole plate fixing frame; 303. heating the module assembly; 304. identifying a turntable; 305. a turntable transition disc; 306. a heating module identifier; 307. rotating a disc; 308. a platform fixing hole; 309. a second leveling hole; 3010. a disc fixing hole; 3011. guiding the deep hole plate; 3012. a deep hole plate visual window; 3013. heating the module cover; 3014. a heating plate; 3015. a temperature controller; 3016. a heat insulation plate; 3017. heating the base; 4. extracting a motion component; 401. vibrating a motor; 402. a Z-axis motor; 403. a bar magnet frame assembly; 404. a magnetic bar sleeve frame component; 405. a liquid baffle; 406. a drive motor; 407. a magnetic bar mounting plate; 408. lightening holes; 409. a magnetic bar assembly; 4010. a magnetic bar sleeve plate; 4011. the magnetic bar is sleeved on the left side plate; 4012. the magnetic bar is sleeved on the right side plate; 4013. a positioning bead; 5. an electronic control assembly; 501. a switching power supply; 502. a main control board; 503. an illuminating lamp; 504. driving a motor; 505. a sterilizing lamp; 6. a rear housing; 7. a touch screen; 8. opening and closing the door; 9. and (4) an observation window.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element to which the reference is made must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, and for example, "connected" may be either fixedly connected or detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Referring to fig. 1-15, the present invention provides an embodiment: a nucleic acid extractor comprises a nucleic acid extractor body 1, a chassis component 2, a turntable component 3, an extraction motion component 4 and an electric control component 5; the nucleic acid extraction instrument main body 1 comprises a chassis component 2, a turntable component 3, an extraction motion component 4 and an electric control component 5, wherein the chassis component 2 comprises an installation base 201, an upright post supporting component 202 and a hollow rotary platform 203, the chassis component 2 fixes and levels the extraction motion component 4 through the upright post supporting component 202, the upright post supporting component 202 is used for fixing and leveling the extraction motion component 4, the chassis component 2 supports the turntable component 3 through the hollow rotary platform 203, four corners at the bottom of the upright post supporting component 202 are respectively provided with an upright post fixing hole 204 and a first leveling hole 205, the upright post supporting component 202 is fixedly installed through the upright post fixing hole 204, after a flat end fastening screw is installed in the first leveling hole 205, the through hole elastic flat end fastening screw can adjust the relative horizontal position of the extraction motion component 4 relative to the turntable component 3, and the turntable component 3 comprises a turntable main body 301, The deep hole plate fixing frame 302 and the heating module assembly 303, the rotary disc assembly 3 is fixed on the hollow rotary platform 203 through the rotary disc transition disc 305, eight groups of equidistant second leveling holes 309 and disc fixing holes 3010 are arranged on the periphery of the surface of the rotary disc transition disc 305, after a leveling end fastening screw is installed in the second leveling hole 309 of the rotary disc transition disc 305, the relative horizontal position of each rotary disc position 307 relative to the extraction motion assembly 4 can be adjusted through a through hole tightness leveling end fastening screw, four groups of equidistant platform fixing holes 308 are arranged in the central position of the surface of the rotary disc transition disc 305, the rotary disc transition disc 305 is fixedly installed with the hollow rotary platform 203 through the platform fixing holes 308, eight groups of equidistant deep hole plate fixing frames 302 are installed on the periphery of the top of the rotary disc main body 301 through the rotary disc positions 307, the deep hole plate fixing frames 302 are used for placing and fixing the deep hole plates, and the heating module assemblies 303 are installed inside the two adjacent deep hole plate fixing frames 302, the heating module assembly 303 is detachable, so that a person can conveniently replace the matched heating module assembly 303 according to different deep hole plates to improve the extraction effect, the extraction movement assembly 4 comprises a vibration motor 401, a Z-axis motor 402, a magnetic rod frame assembly 403, a magnetic rod sleeve frame assembly 404, a liquid baffle plate 405 and a driving motor 406, the vibration motor 401 is installed at the top of one side of the extraction movement assembly 4, the vibration motor 401 is used for driving cell sap to vibrate, the added lysate and the cell sap can be fully mixed and react, cells are cracked, nucleic acid is released, the Z-axis motor 402 is arranged at the top of one side of the extraction movement assembly 4, which is far away from the vibration motor 401, the Z-axis motor 402 is used for driving the turntable assembly 3 to rotate, the magnetic rod sleeve frame assembly 404 is arranged at the front side of the extraction movement assembly 4, the magnetic rod frame assembly 403 is arranged above the magnetic rod sleeve frame assembly 404 at the front side of the extraction movement assembly 4, bar magnet cover frame subassembly 404 and bar magnet frame subassembly 403 make things convenient for the installation of bar magnet subassembly 409, driving motor 406 is installed with the junction of drawing motion subassembly 4 to liquid baffle 405, driving motor 406 is used for driving liquid baffle 405 and rotates, make liquid baffle 405 be located the below of bar magnet subassembly 409, then the adsorbed magnetic bead falls into on liquid baffle 405 on the bar magnet subassembly 409, the front end department of automatically controlled subassembly 5 bottom installs and light 503 and sterilamp 505, light 503 and sterilamp 505 are used for throwing light on and disinfecting operational environment.

Further, the position department that carousel main part 301 surface and deep hole board fixed frame 302 correspond is equipped with carousel sign 304, and carousel sign 304 is used for marking each group of deep hole board fixed frame 302, and the position department that carousel main part 301 surface and heating module subassembly 303 correspond is equipped with heating module sign 306, and heating module sign 306 is used for marking heating module subassembly 303.

Further, the inside of the fixed frame 302 of deep hole board is equipped with deep hole board direction 3011, and the front end of the fixed frame 302 of deep hole board is equipped with the visual window 3012 of deep hole board, and the deep hole board direction 3011 is convenient for placing and fixing of deep hole board, can observe and accurately adjust the magnetic rod subassembly 409 depth of fall position through the visual window 3012 of deep hole board of the fixed frame 302 of deep hole board.

Further, the heating module assembly 303 includes a heating module cover 3013, a heating sheet 3014, a temperature controller 3015, a heat insulation board 3016 and a heating base 3017, the heating sheet 3014 is embedded in the top of the heating module cover 3013, the heating sheet 3014 is powered on to heat, the temperature controller 3015 is arranged on one side of the heating sheet 3014, the temperature controller 3015 controls the temperature, the heat insulation board 3016 is installed on the top of the heating module cover 3013, the heat insulation board 3016 is used for heat insulation, the heating base 3017 is embedded in the heat insulation board 3016, and the heating base 3017 can be replaced according to different deep hole boards of a user.

Further, the magnetic rod assembly 403 comprises a magnetic rod mounting plate 407, a lightening hole 408 and a magnetic rod assembly 409, wherein the lightening hole 408 is formed in the surface of the magnetic rod mounting plate 407, the lightening hole 408 can effectively lighten the weight of the magnetic rod assembly 403, the magnetic rod assembly 409 is arranged at the bottom of the magnetic rod mounting plate 407, and the magnetic rod assembly 409 is used for sucking out magnetic beads in the lysed cell sap.

Further, bar magnet stock cover frame subassembly 404 includes bar magnet lagging 4010, bar magnet cover left side board 4011, bar magnet cover right side board 4012 and location pearl 4013, and has bar magnet lagging 4010 through location pearl 4013 fixed mounting between bar magnet cover left side board 4011 and the bar magnet cover right side board 4012, through adjusting bar magnet lagging 4010 that bar magnet cover left side board 4011 and bar magnet cover right side board 4012 cooperate different specifications, through the position of the fixed bar magnet lagging 4010 of location pearl 4013.

Further, the central position department of automatically controlled subassembly 5 top rear side is equipped with main control board 502, one side at automatically controlled subassembly 5 top is equipped with motor drive 504, motor drive 504 is arranged in controlling the motor in the equipment, and one side that motor drive 504 was kept away from at automatically controlled subassembly 5 top is equipped with switching power supply 501, and switching power supply 501 is used for controlling the power supply of some electrical equipment in the equipment.

Further, the positive top of nucleic acid extraction appearance main part 1 is equipped with touch-sensitive screen 7, touch-sensitive screen 7 makes things convenient for personnel to operate this equipment, the rear side of nucleic acid extraction appearance main part 1 is equipped with backshell 6, open the backshell 6 back, the part in the equipment is all concentrated together, make things convenient for personnel to maintain and maintain, the positive bottom of nucleic acid extraction appearance main part 1 is equipped with switch door 8, switch door 8 makes things convenient for personnel to open equipment, put into the cell sap, and the surface of switch door 8 is equipped with observation window 9, observation window 9 is convenient for personnel observation equipment inside behavior.

Further, the electric control assembly 5 is electrically connected with the touch screen 7 through a wire, the switching power supply 501 is electrically connected with the illuminating lamp 503, the sterilizing lamp 505 and the temperature controller 3015 through wires, the motor driver 504 is electrically connected with the vibration motor 401 and the Z-axis motor 402 through wires, and the temperature controller 3015 is electrically connected with the heating plate 3014 through wires.

The working principle is as follows: during the use, personnel can add the lysate in with the cell sap then put into equipment, then realize the mixing and the abundant reaction of reaction solution through mechanical motion and heating, the cell lysis, release nucleic acid, then control driving motor 406 and drive baffle 405 and rotate, make baffle 405 be located the below of bar magnet subassembly 409, then the magnetic bead that adsorbs on the bar magnet subassembly 409 falls into baffle 405, carry out the accounting and draw, every time of using one end, can pull down backshell 6 and maintain the inside device of equipment, and equipment chassis subassembly 2, draw motion subassembly 4 all have leveling mechanism, guarantee that the nucleic acid extraction process is even.

The details of the present invention are well known to those skilled in the art.

Finally, it is to be noted that: the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the examples, it should be understood by those skilled in the art that the technical solutions of the present invention can be modified and replaced with equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the scope of the claims of the present invention.

Claims (9)

1. A nucleic acid extractor comprises a nucleic acid extractor main body (1), a chassis component (2), a turntable component (3), an extraction motion component (4) and an electric control component (5); the method is characterized in that: the nucleic acid extraction instrument main body (1) comprises a chassis component (2), a turntable component (3), an extraction motion component (4) and an electric control component (5), wherein the chassis component (2) comprises an installation base (201), an upright post supporting component (202) and a hollow rotating platform (203), the chassis component (2) is fixed and leveled by the upright post supporting component (202), the turntable component (3) is supported by the chassis component (2) by the hollow rotating platform (203), four corners at the bottom of the upright post supporting component (202) are respectively provided with an upright post fixing hole (204) and a first leveling hole (205), the turntable component (3) comprises a turntable main body (301), a deep hole plate (302) and a heating module component (303), and the turntable component (3) is fixed on the hollow rotating platform (203) by a turntable transition plate (305), a week on carousel transition dish (305) surface is equipped with eight equidistant second leveling holes (309) and disc fixed orifices (3010), the central point department on carousel transition dish (305) surface is equipped with four equidistant platform fixed orifices (308), a week at carousel main part (301) top installs eight equidistant deep hole board fixed frames (302) through carousel position (307), and wherein adjacent two sets of deep hole board fixed frames (302) internally mounted have heating module subassembly (303), it includes shock dynamo (401), Z axle motor (402), bar magnet frame subassembly (403), bar magnet frame set subassembly (404), keeps off liquid board (405) and driving motor (406) to draw motion subassembly (4), and draws the top position department of motion subassembly (4) one side and install shock dynamo (401), it is equipped with Z axle motor (402) to draw motion subassembly (4) to keep away from the one side top of shock dynamo (401), draw the front side of motion subassembly (4) to be equipped with bar magnet cover frame subassembly (404), it is equipped with bar magnet frame subassembly (403) to draw the top that motion subassembly (4) front side is located bar magnet cover frame subassembly (404), driving motor (406) are installed with the junction of drawing motion subassembly (4) in fender liquid board (405), the front end department of automatically controlled subassembly (5) bottom install with light (503) and sterilamp (505).

2. The nucleic acid extractor of claim 1, wherein: the rotary table is characterized in that a rotary table mark (304) is arranged at a position, corresponding to the deep hole plate fixing frame (302), on the surface of the rotary table main body (301), and a heating module mark (306) is arranged at a position, corresponding to the heating module component (303), on the surface of the rotary table main body (301).

3. The nucleic acid extractor of claim 1, wherein: the inside of the fixed frame of deep hole board (302) is equipped with deep hole board direction (3011), the front end of the fixed frame of deep hole board (302) is equipped with deep hole board visual window (3012).

4. The nucleic acid extractor of claim 1, wherein: heating module subassembly (303) is including heating module lid (3013), heating plate (3014), temperature controller (3015), heat insulating board (3016) and heating base (3017), and the top embedding of heating module lid (3013) has heating plate (3014), and one side of heating plate (3014) is equipped with temperature controller (3015), and installs heat insulating board (3016) at the top of heating module lid (3013), and the inside embedding of heat insulating board (3016) has heating base (3017).

5. The nucleic acid extractor of claim 1, wherein: the magnetic rod assembly (403) comprises a magnetic rod mounting plate (407), lightening holes (408) and a magnetic rod assembly (409), wherein the lightening holes (408) are formed in the surface of the magnetic rod mounting plate (407), and the magnetic rod assembly (409) is arranged at the bottom of the magnetic rod mounting plate (407).

6. The nucleic acid extractor of claim 1, wherein: bar magnet stock set subassembly (404) includes bar magnet lagging (4010), bar magnet cover left side board (4011), bar magnet cover right side board (4012) and location pearl (4013), and has bar magnet lagging (4010) through location pearl (4013) fixed mounting between bar magnet cover left side board (4011) and bar magnet cover right side board (4012).

7. The nucleic acid extractor of claim 1, wherein: the central position department of automatically controlled subassembly (5) top rear side is equipped with main control board (502), one side at automatically controlled subassembly (5) top is equipped with motor drive (504), one side that motor drive (504) were kept away from at automatically controlled subassembly (5) top is equipped with switching power supply (501).

8. The nucleic acid extractor of claim 1, wherein: the positive top of nucleic acid extraction appearance main part (1) is equipped with touch-sensitive screen (7), the rear side of nucleic acid extraction appearance main part (1) is equipped with backshell (6), the positive bottom of nucleic acid extraction appearance main part (1) is equipped with switch door (8), and the surface of switch door (8) is equipped with observation window (9).

9. The nucleic acid extractor of claim 1, wherein: the electric control assembly (5) is electrically connected with the touch screen (7) through a lead, the switch power supply (501) is electrically connected with the illuminating lamp (503), the sterilizing lamp (505) and the temperature controller (3015) through leads, the motor drive (504) is electrically connected with the vibration motor (401) and the Z-axis motor (402) through leads, and the temperature controller (3015) is electrically connected with the heating plate (3014) through leads.

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