CN213852278U - Plasma sterilization and biocompatibility improvement device for corneal contact lens - Google Patents

Plasma sterilization and biocompatibility improvement device for corneal contact lens Download PDF

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CN213852278U
CN213852278U CN202022848290.9U CN202022848290U CN213852278U CN 213852278 U CN213852278 U CN 213852278U CN 202022848290 U CN202022848290 U CN 202022848290U CN 213852278 U CN213852278 U CN 213852278U
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quartz glass
cavity
contact lens
glass cavity
biocompatibility
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沈洁
孟月东
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Hefei Institutes of Physical Science of CAS
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Hefei Institutes of Physical Science of CAS
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Abstract

The utility model provides a corneal contact lens plasma sterilization and biocompatibility improve device, include: the device comprises a device shell, a quartz glass cavity, an external electrode pair, a liquid injector, a plurality of flow controllers, an excitation power supply, a PLC (programmable logic controller) and a plurality of electromagnetic valves; the quartz glass cavity is fixed in the device shell through two insulating supports, a sealing door is arranged at the opening of the quartz glass cavity, and a glass observation window and a metal shielding net are arranged on the sealing door; the metal shielding net and the device shell are grounded; the external electrode pair is installed outside the quartz glass cavity, external electrode pair is connected with excitation power supply output electricity, the utility model discloses a let in different gases, the functional group that corresponds on the grafting in contact lens surface molecular group improves hydrophilicity or hydrophobicity etc. improves the travelling comfort of wearing of lens to improve lens biocompatibility, and can handle the sterilization through plasma gas.

Description

Plasma sterilization and biocompatibility improvement device for corneal contact lens
Technical Field
The utility model relates to the field of electronic equipment, especially, relate to a corneal contact lens plasma biocompatibility improves and aseptic processing apparatus.
Background
The corneal contact lens is directly attached to the lacrimal fluid layer of the cornea, is compatible with human eye physiology, and achieves the aim of vision correction. The corneal contact lens has the advantages of oxygen permeability, better visual effect, astigmatism correction and the like. However, the surface of the high polymer material of the corneal contact lens has hydrophobicity, and the wettability of the surface of the lens is poor, so that the biocompatibility problem is easily caused:
during the wearing process of the lens, proteins and lipids in tears are easily deposited on the surface of the lens, so that the transparency and oxygen permeability of the lens are reduced, the wearing comfort is reduced, and the visual effect is influenced. Meanwhile, bacteria are easily adhered and bred on the surface of the lens, and inflammatory reactions such as conjunctivitis and keratitis of eyes are caused. In addition, the treatment of the lens by the care solution is also easy to cause anaphylactic reaction during wearing. Contact lenses may come into contact with bacteria or viruses during production and use, causing eye infections and causing various diseases of the eye. Irregular contact lens wear and care are also important factors in the development of microbial keratitis, and therefore are particularly important in the aseptic treatment of contact lenses.
The treatment of the corneal contact lens by the prior patent technology mainly focuses on introducing different atmospheres to generate plasmas, modifying the surface of the lens under the action of the plasmas, and improving the surface hydrophilicity of a material to improve the biocompatibility, but the lens cannot meet the aseptic requirement in the treatment process. Meanwhile, the corneal contact lens is in direct contact with eyeball tissues, and the surface of the material cannot be polluted during plasma treatment. If the device electrode is built in, there is a possibility that metal ions may be sputtered onto the surface of the contact lens to contaminate the lens surface during plasma generation and discharge processing of materials.
SUMMERY OF THE UTILITY MODEL
The utility model discloses to above application in cornea contact aseptic ization and biocompatibility and to the material cleanliness factor requirement problem, the utility model discloses an external electrode forms the low atmospheric pressure through vacuum apparatus in the quartz glass cavity, produces plasma's device, the device can be through different process control to reach aseptic and improvement biocompatibility's effect.
The technical scheme of the utility model is that: a corneal contact lens plasma sterilization and biocompatibility improving apparatus comprising: the device comprises a device shell, a quartz glass cavity, an external electrode pair, a liquid injector, a plurality of flow controllers, an excitation power supply, a PLC (programmable logic controller) and a plurality of electromagnetic valves;
the quartz glass cavity is fixed in the device shell through two insulating supports, a sealing door is arranged at the opening of the quartz glass cavity, and a glass observation window and a metal shielding net are arranged on the sealing door; the metal shielding net and the device shell are grounded;
the external electrode pair is arranged outside the quartz glass cavity body and is electrically connected with the output of the excitation power supply;
the liquid injector comprises a liquid level sensor and a quantitative liquid injection device, wherein the liquid level sensor is used for detecting the liquid level of the hydrogen peroxide liquid;
quartz glass cavity leaves vacuum cavity evacuation interface for be connected with the vacuum pump through external vacuum pump interface, through the operation of PLC control system control vacuum pump, realize the inside low atmospheric pressure of quartz glass cavity, and install the vacuum gauge pipe of measuring atmospheric pressure on the pipeline at vacuum cavity evacuation kneck, be used for detecting the atmospheric pressure in the quartz glass cavity, and still be connected with fifth solenoid valve Q at vacuum cavity evacuation kneck5And is connected with the atmosphere through a filter for air bleeding so as to realize the return of the quartz glass cavity from the low pressure to the atmospheric pressure.
Further, the excitation power supply is a radio frequency power supply or a high frequency power supply, and the frequency of the high frequency power supply is 1kHz-1 MHz.
Further, the external electrode pair is a metal sheet with a predetermined width.
Furthermore, the quartz glass cavity is a cylindrical cavity with an opening at one end, and openings are reserved at the other end and the side wall of the cavity and used as interfaces for vacuumizing, air intake and liquid injection, and used for vacuumizing, entering carrier gases in different atmospheres and injecting hydrogen peroxide disinfectant.
Further, theThe quartz glass cavity is provided with a vacuum cavity gas path interface and is respectively connected with a second electromagnetic valve Q2And a third electromagnetic valve Q3Said second electromagnetic valve Q2A first flow controller is connected, and the third electromagnetic valve Q3And the first flow controller and the second flow controller are respectively connected with an external air source.
The quartz glass cavity is provided with a first external air path interface and a second external air path interface which are used as air inlet interfaces of different gases.
Drawings
FIG. 1 is a front view of a plasma processing apparatus;
FIG. 2 is a schematic view of a plasma processing apparatus.
1. The device comprises a device shell, 2 external electrode pairs, 2 and 3 sealing doors, 4 metal shielding nets, 5 a support frame, 6 a first flow controller, 7 a second flow controller, 8 a first external air path interface, 9 a second external air path interface, 10 an external vacuum pump interface, 11 an excitation power supply, 12 a vacuum cavity air path interface, 13 a vacuum cavity vacuumizing interface, 14 a PLC (programmable logic controller), 15 a quartz glass cavity, 16 a touch screen, 17 a liquid injector and Q1A first electromagnetic valve, Q2A second electromagnetic valve, Q3A third electromagnetic valve, Q4Fourth electromagnetic valve, Q5And a fifth electromagnetic valve.
The specific implementation mode is as follows:
the technical solution in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without any inventive work belong to the protection scope of the present invention based on the embodiments of the present invention.
According to the embodiment of the utility model, referring to fig. 1-2, a corneal contact lens plasma sterilization and biocompatibility improvement device, the main body comprises a device shell 1, a quartz glass cavity 15, an external electrode pair 2, a liquid injector 17, a flow controller, an excitation power supply, a PLC controller, a solenoid valve and the like.
The quartz glass cavity 15 is a cylindrical cavity with an opening at one end, and openings are reserved at the other end and the side wall of the cavity and used as interfaces for vacuumizing, air inlet and liquid injection, and used for vacuumizing, entering carrier gas in different atmospheres and injecting hydrogen peroxide disinfectant. The quartz glass cavity 15 comprises a first external air path interface 8 and a second external air path interface 9 which are used as air inlet interfaces.
The quartz glass chamber 15 is fixed in the device housing 1 by two insulating holders 5. The opening of the quartz glass cavity 15 is provided with a sealing door 3, and the sealing door 3 is provided with a glass observation window and a metal shielding net 4. The metal shielding net 4 and the device shell 1 are grounded to form a shielding system for shielding electromagnetic interference generated by plasma.
The external electrode pair 2 is a metal sheet with a certain width and is arranged outside the quartz glass cavity body in a close fit mode. The external electrode pair 2 is electrically connected with the output of the excitation power supply 11. The excitation power supply 11 may be a radio frequency power supply (including a matcher), or a high frequency excitation power supply with a frequency of 1kHz to 1 MHz.
The liquid injector 17 comprises a liquid level sensor and a quantitative liquid injection device. The liquid level sensor is used for detecting the liquid level of the hydrogen peroxide liquid, and if the liquid level of the hydrogen peroxide is not enough, the liquid level sensor gives an alarm to prompt and forbids the plasma processing lens processing flow to continue.
The quartz glass cavity 15 is provided with a vacuum cavity vacuumizing interface 13 for connecting with a vacuum pump through an external vacuum pump interface 10, the vacuum pump is controlled to run through a PLC control system, low air pressure inside the quartz cavity is achieved, and a vacuum gauge pipe for measuring air pressure is arranged on a pipeline at the vacuum cavity vacuumizing interface 13 and used for detecting the air pressure in the quartz glass cavity. And a fifth electromagnetic valve Q is also connected at the vacuum-pumping interface 13 of the vacuum cavity5And is connected to the atmosphere through a filter for degassing to achieve the return of the quartz glass chamber 15 from the low pressure to the atmospheric pressure.
The quartz glass cavity 15 is provided with a vacuum cavity gas path interface 12 which is respectively connected with a second electromagnetValve Q2And a third electromagnetic valve Q3Said second electromagnetic valve Q2A first flow controller 6 is connected, and the third electromagnetic valve Q3A second flow controller 7 is connected, the first flow controller 6 and the second flow controller 7 are respectively connected with an external air source, and the external air source can be CF4And oxygen, argon, nitrogen, air, and the like.
The working process of the plasma processing device is as follows:
and placing the lens to be treated in a disinfection box and a quartz cavity. Firstly, corresponding control parameters are set through the touch screen 16, and meanwhile, the plasma processing device is started, and the device carries out plasma processing under the control of the set parameters through the PLC 14.
First, the fourth solenoid valve Q is opened4And vacuumizing by a vacuum pump, and opening the second/third electromagnetic valve Q when the vacuum degree reaches a set parameter (such as 10Pa)2/Q3A single atmosphere such as argon, nitrogen, oxygen or a mixture of argon, nitrogen and oxygen is flushed. The biocompatibility is improved by improving the hydrophilicity of the corneal contact lens through different atmosphere plasma treatment. The second/third electromagnetic valve Q can also be controlled by process regulation2/Q3The opening or closing and the sequence of the plasma processing are combined for different gases; preferably, the mixed gas may be a carbon tetrafluoride and oxygen mixed gas.
Corresponding functional groups are grafted in the surface molecular groups of the corneal contact lens through different gases, so that the hydrophilicity or hydrophobicity and the like are improved, the wearing comfort of the lens is improved, and the biocompatibility of the lens is improved.
Close the second/third solenoid Q2And Q3Continuing to vacuumize, and then opening the first electromagnetic valve Q1And injecting a certain amount of hydrogen peroxide liquid, and rapidly atomizing and diffusing the hydrogen peroxide into the quartz vacuum cavity under the action of atmospheric pressure. Then the fifth electromagnetic valve Q is opened5And aerating to accelerate the hydrogen peroxide diffusion process. When the vacuum chamber reaches the preset air pressure, the exciting power supply is started to generate plasma, so that the contact lens meets the requirement of quick sterilization.
Although illustrative embodiments of the invention have been described above to facilitate the understanding of the invention by those skilled in the art, it should be understood that the invention is not limited to the scope of the embodiments, and that various changes will become apparent to those skilled in the art once they are within the spirit and scope of the invention as defined and defined in the appended claims.

Claims (6)

1. A corneal contact lens plasma sterilization and biocompatibility improving apparatus, comprising: the device comprises a device shell, a quartz glass cavity, an external electrode pair, a liquid injector, a plurality of flow controllers, an excitation power supply, a PLC (programmable logic controller) and a plurality of electromagnetic valves;
the quartz glass cavity is fixed in the device shell through two insulating supports, a sealing door is arranged at the opening of the quartz glass cavity, and a glass observation window and a metal shielding net are arranged on the sealing door; the metal shielding net and the device shell are grounded;
the external electrode pair is arranged outside the quartz glass cavity body and is electrically connected with the output of the excitation power supply;
the liquid injector comprises a liquid level sensor and a quantitative liquid injection device, wherein the liquid level sensor is used for detecting the liquid level of the hydrogen peroxide liquid;
quartz glass cavity leaves vacuum cavity evacuation interface for be connected with the vacuum pump through external vacuum pump interface, through the operation of PLC control system control vacuum pump, realize the inside low atmospheric pressure of quartz glass cavity, and install the vacuum gauge pipe of measuring atmospheric pressure on the pipeline at vacuum cavity evacuation kneck, be used for detecting the atmospheric pressure in the quartz glass cavity, and still be connected with fifth solenoid valve Q at vacuum cavity evacuation kneck5And is connected with the atmosphere through a filter for air bleeding so as to realize the return of the quartz glass cavity from the low pressure to the atmospheric pressure.
2. A corneal contact lens plasma sterilization and biocompatibility improving apparatus as defined in claim 1, wherein said excitation power source is a radio frequency power source or a high frequency power source, and said high frequency power source has a frequency of 1kHz to 1 MHz.
3. A corneal contact lens plasma sterilization and biocompatibility improving apparatus as defined in claim 1, wherein said external electrode pair is a metal sheet having a predetermined width.
4. A corneal contact lens plasma sterilization and biocompatibility improving apparatus as defined in claim 1,
the quartz glass cavity is a cylindrical cavity with an opening at one end, and openings are reserved at the other end and the side wall of the cavity and used as interfaces for vacuumizing, air inlet and liquid injection, and used for vacuumizing, entering carrier gas in different atmospheres and injecting hydrogen peroxide disinfectant.
5. A corneal contact lens plasma sterilization and biocompatibility improving apparatus as defined in claim 1, wherein said quartz glass chamber is provided with a vacuum chamber gas path interface, and is respectively connected with a second electromagnetic valve Q2And a third electromagnetic valve Q3Said second electromagnetic valve Q2A first flow controller is connected, and the third electromagnetic valve Q3And the first flow controller and the second flow controller are respectively connected with an external air source.
6. A corneal contact lens plasma sterilization and biocompatibility improving apparatus as defined in claim 1, wherein said quartz glass chamber is provided with a first external air passage interface and a second external air passage interface for different air inlet interfaces.
CN202022848290.9U 2020-12-02 2020-12-02 Plasma sterilization and biocompatibility improvement device for corneal contact lens Active CN213852278U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202022848290.9U CN213852278U (en) 2020-12-02 2020-12-02 Plasma sterilization and biocompatibility improvement device for corneal contact lens

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202022848290.9U CN213852278U (en) 2020-12-02 2020-12-02 Plasma sterilization and biocompatibility improvement device for corneal contact lens

Publications (1)

Publication Number Publication Date
CN213852278U true CN213852278U (en) 2021-08-03

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CN202022848290.9U Active CN213852278U (en) 2020-12-02 2020-12-02 Plasma sterilization and biocompatibility improvement device for corneal contact lens

Country Status (1)

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CN (1) CN213852278U (en)

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