CN213813012U

CN213813012U - Sampling device for detecting purified antibody

Info

Publication number: CN213813012U
Application number: CN202022642309.4U
Authority: CN
Inventors: 陈旭华; 汪渊; 谌敦华
Original assignee: Shanghai Cymbal Poetry Biotechnology Co ltd
Current assignee: Shanghai Cymbal Poetry Biotechnology Co ltd
Priority date: 2020-11-16
Filing date: 2020-11-16
Publication date: 2021-07-27
Anticipated expiration: 2030-11-16

Abstract

The utility model discloses a sampling device for purification antibody detection usefulness, including framework, main shaft, driven shaft and brush, the bearing of department is connected with the main shaft in the middle of the framework inboard, and the welding of the main shaft outside has first conical gear, the welding of the outside has second conical gear in the middle of the driven shaft, and second conical gear the place ahead inboard is fixed with the quarter butt, the inside rack that is provided with in framework right side, and the meshing of rack top has the rotor plate, the main shaft outside is fixed with the scraper blade, and the main shaft below outside still the bearing be connected with the otter board to the welding of main shaft left side has the connecting plate. This a sampling device for purification antibody detects usefulness installs water inlet, delivery port, connecting plate and brush for the water that gets into through the water inlet is cooperating the brush and can effectually wash the brush of wiping in rotatory in-process to framework bottom inner wall, then the sewage that has washd can directly flow from the delivery port, thereby makes framework bottom inner wall cleaner in the cleaning process.

Description

Sampling device for detecting purified antibody

Technical Field

The utility model relates to a purification antibody technical field specifically is a sampling device for purification antibody detects usefulness.

Background

The antibody is a liquid secreted by plasma cells, is used by an immune system to identify bacteria, viruses and the like invading a human body, is widely applied in the fields of life science research and medicine as a core reagent of immunoassay, in addition, the antibody needs to be purified in the preparation process, the purified antibody needs to be sampled and detected after the research and development are completed, and the existing detection devices still have defects, such as:

1. the existing sampling device for detecting the purified antibody is easy to expose the purified antibody outside the air in the sampling process, so that the purified antibody and dust in the air are oxidized, and the accuracy of the detection of the purified antibody is influenced;

2. after the purified antibody is detected by the conventional sampling device for detecting the purified antibody, the detection effect of the purified antibody at the next time is seriously influenced due to incomplete cleaning, so that inconvenience is brought to people;

therefore, it is very important to provide a sampling device for detecting purified antibodies, which can solve the above problems well.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a sampling device for purification antibody detection usefulness, the in-process of taking a sample is being carried out to the sampling device who purification antibody detection usefulness on solving the present market that above-mentioned background art provided, expose the purification antibody in the air outside easily, lead to the dust in purification antibody and the air to take place the oxidation, thereby the accuracy that purification antibody detection was detected has been influenced, and the sampling device that current purification antibody detection was used is detecting the back to the purification antibody, because wash and not thoroughly lead to seriously influencing the problem of next purification antibody detection effect.

In order to achieve the above object, the utility model provides a following technical scheme: a sampling device for detecting a purified antibody comprises a frame body, a main shaft, a driven shaft and a hairbrush, wherein the main shaft is connected to the middle of the inner side of the frame body through a bearing, a first conical gear is welded to the outer side of the main shaft, the driven shaft is fixed to the right side of the first conical gear, a second conical gear is welded to the outer side of the middle of the driven shaft, a short rod is fixed to the inner side in front of the second conical gear, a rack is arranged inside the right side of the frame body, a rotating plate is meshed above the rack, an extraction cylinder penetrates through the inside of the right side of the frame body, a scraping plate is fixed to the outer side of the main shaft, a screen plate is connected to the outer side of the lower portion of the main shaft through a bearing, and a connecting plate is welded to the left side of the main shaft; the rack inboard is provided with the vaulting pole, and both ends all around the vaulting pole with the framework inside for welded fastening to the welding of rack right side has the guide bar, and guide bar right-hand member screw connection has a piston moreover, the guide way has all been seted up to an extraction section of thick bamboo inner wall, and straight line sliding structure about guide way and piston constitute to extraction section of thick bamboo left side below has still seted up communicating pipe.

Further, a test paper inlet is formed in the left side of the frame body, a water inlet is formed in the upper portion of the frame body, and a water outlet is formed in the bottom of the frame body.

Furthermore, a rotary table is fixed on the outer side of the short rod, a pull rod is welded in front of the rotary table, and the outer side of the pull rod penetrates through the inner side of the rotary plate.

Furthermore, a through groove is formed in the inner side of the front of the rotating plate, a rotating rod is fixed on the inner side of the lower portion of the rotating plate, and the outer side of the lower portion of the rotating plate is in a gear shape.

Furthermore, test paper is bonded above the screen plate, and the vertical center line of the screen plate is overlapped with the vertical center line of the frame body.

Further, the brush is all installed on the connecting plate left side, and the brush outside all contacts with framework below inner wall.

Compared with the prior art, the beneficial effects of the utility model are that:

(1) the utility model discloses be provided with the carousel, the dead man, the rack, the vaulting pole, the guide bar, a piston, an extraction section of thick bamboo, the guide way, communicating pipe, the commentaries on classics board, the bull stick, otter board and test paper, make through the carousel, the dead man, the rack, the vaulting pole, the guide bar, a piston, an extraction section of thick bamboo, the guide way, communicating pipe, the commentaries on classics board, the through groove, the bull stick, the otter board can be effectual make whole device with the purification antibody extraction in the preparation of the outside take place the color reaction in its inboard and test paper even contact, thereby people judge the purity and the quality to reach standard of purification antibody through the color degree to test paper, avoided whole device to take place the problem of oxidation with the dust in the outside air in the process of taking a sample simultaneously, and then improved the test effect and the test quality of the sampling device that purification antibody was tested;

(2) the utility model discloses be provided with water inlet, delivery port, connecting plate and brush for the water that gets into through the water inlet is cooperating the brush and can effectually wash the brush of wiping to framework bottom inner wall in rotatory in-process, then the sewage that has cleaned can directly flow from the delivery port, thereby makes framework bottom inner wall cleaner in the cleaning process, and then has avoided the sampling device of whole purification antibody test usefulness to be used the problem of being polluted by inside remaining purification antibody next time.

Drawings

FIG. 1 is a schematic view of the main sectional structure of the present invention;

FIG. 2 is a schematic view of the mounting structure of the second bevel gear and the short rod of the present invention;

FIG. 3 is an enlarged schematic view of the structure at A of FIG. 1 according to the present invention;

fig. 4 is a schematic view of the installation structure of the extraction cylinder and the piston of the present invention.

In the figure: 1. a frame body; 101. a test paper inlet; 102. a water inlet; 103. a water outlet; 2. a main shaft; 3. a first bevel gear; 4. a driven shaft; 5. a second bevel gear; 6. a short bar; 601. a turntable; 602. pulling a rod; 7. a rack; 701. a stay bar; 702. a guide bar; 703. a piston; 8. an extraction cylinder; 801. a guide groove; 802. a communicating pipe; 9. rotating the plate; 901. a through groove; 902. a rotating rod; 10. a screen plate; 1001. test paper; 11. a squeegee; 12. a connecting plate; 1201. and a brush.

Detailed Description

The invention is further described below with reference to the accompanying drawings:

referring to fig. 1-4, the present invention provides a technical solution: a sampling device for detecting a purified antibody comprises a frame body 1, a test paper inlet 101, a water inlet 102, a water outlet 103, a main shaft 2, a first bevel gear 3, a driven shaft 4, a second bevel gear 5, a short rod 6, a turntable 601, a pull rod 602, a rack 7, a support rod 701, a guide rod 702, a piston 703, an extraction cylinder 8, a guide groove 801, a communicating pipe 802, a rotating plate 9, a through groove 901, a rotating rod 902, a screen plate 10, test paper 1001, a scraper 11, a connecting plate 12 and a brush 1201, wherein the main shaft 2 is connected with a bearing in the middle of the inner side of the frame body 1, the first bevel gear 3 is welded on the outer side of the main shaft 2, the driven shaft 4 is fixed on the right side of the first bevel gear 3, the second bevel gear 5 is welded on the outer side of the middle of the driven shaft 4, the short rod 6 is fixed on the inner side in front of the second bevel gear 5, a rack 7 is arranged in the right side of the frame body 1, and the rotating plate 9 is engaged above the rack 7, and an extraction cylinder 8 penetrates through the right side of the frame body 1, a scraping plate 11 is fixed on the outer side of the main shaft 2, a screen plate 10 is connected to the outer side below the main shaft 2 in a bearing mode, and a connecting plate 12 is welded on the left side of the main shaft 2.

The test paper inlet 101 is formed in the left side of the frame body 1, the water inlet 102 is formed in the upper portion of the frame body 1, the water outlet 103 is formed in the bottom of the frame body 1, and due to the structural design, used test paper 1001 is effectively detached and replaced by new test paper 1001 through the test paper inlet 101. The 6 outsides of quarter butt are fixed with carousel 601, and the welding of carousel 601 the place ahead has dead man 602 to the dead man 602 outside runs through in the inboard of changeing board 9, the design of above-mentioned structure, and the water droplet is rotatory simultaneously through the rotatory effectual carousel 601 and the dead man 602 of driving of quarter butt 6, thereby makes and can effectually drive when rotatory through dead man 602 and change board 9 and cooperate logical groove 901 horizontal hunting, has increased holistic transmission effect. The rack 7 inboard is provided with vaulting pole 701, and both ends all around the vaulting pole 701 with framework 1 before inside back be welded fastening to rack 7 right side welding has guide bar 702, and guide bar 702 right-hand member screwed connection has piston 703 moreover, the design of above-mentioned structure, makes through the effectual drive guide bar 702 of rack 7 horizontal hunting in-process and moves about in an extraction section of thick bamboo 8, has done effectual foreshadowing for the later stage extraction purified antibody.

The utility model discloses in, guide way 801 has all been seted up to an extraction section of thick bamboo 8 inner wall, and straight line sliding structure about guide way 801 and piston 703 constitute, and communicating pipe 802 has still been seted up to an extraction section of thick bamboo 8 left side below, the design of above-mentioned structure, make through piston 703 effectual cooperation guide way 801 with the extraction of purification antibody inside an extraction section of thick bamboo 8, thereby make the purification antibody through extracting the communicating pipe 802 stream of a 8 below on the test paper 1001 of otter board 10 top, and then be convenient for the purification antibody and take place to discolour with test paper 1001 contact, purity and the quality to reach standard of purification antibody are judged to the degree of discolouring through test paper 1001 then. The through groove 901 is formed in the inner side in front of the rotating plate 9, the rotating rod 902 is fixed on the inner side below the rotating plate 9, and the outer side below the rotating plate 9 is in a gear shape. The test paper 1001 is bonded above the screen plate 10, the vertical center line of the screen plate 10 and the vertical center line of the frame body 1 coincide with each other, and the design of the structure enables the purity and the standard reaching degree of the purified antibody to be effectively tested through the contact between the test paper 1001 and the purified antibody, and the overall practicability is improved. Brush 1201 is all installed on connecting plate 12 left side, and the brush 1201 outside all contacts with framework 1 below inner wall, and the design of above-mentioned structure for through brush 1201 effectual in-process rotatory clear up framework 1 below inner wall and clean, be convenient for framework 1 bottom inner wall cleaner in the cleaning process, increased the practicality.

The utility model discloses a theory of operation does: when the sampling device for detecting the purified antibody is used, firstly, as shown in fig. 1-4, the extraction cylinder 8 on the right side of the frame body 1 is inserted into the purified antibody preparation, then the servo motor is started to drive the main shaft 2 to rotate, the first bevel gear 3 is driven to rotate through the rotation of the main shaft 2, then the driven shaft 4 and the second bevel gear 5 are driven to rotate through the rotation of the first bevel gear 3, when the second bevel gear 5 rotates, the short rod 6 and the turntable 601 can be effectively driven to rotate, so that the pull rod 602 is driven to be matched with the through groove 901 to drive the rotating plate 9 to swing left and right through the rotation of the rotating plate 9, the rack 7 is effectively driven to be matched with the support rod 701 to move left and right through the left and right swing of the support rod 701, when the support rod 701 moves left and right, the guide rod 702 and the piston 703 are matched with the guide groove 801 on the inner wall of the extraction cylinder 8 to move left and right, so that the purified antibody in the outer preparation can be effectively extracted inside the extraction cylinder 8 through the piston 703 moving left and right, further, the purified antibody extracted from the interior of the extraction cylinder 8 flows into the outer side of the test paper 1001 above the screen plate 10 through the communication pipe 802 at the bottom of the left side of the extraction cylinder 8, at this time, the main shaft 2 can also drive the scraper 11 to rotate when rotating, so that the purified antibody above the test paper 1001 can be effectively and uniformly coated on the outer side of the test paper through the scraper 11 in the rotating process, then the purity and the standard quality of the purified antibody are judged according to the color change degree of the test paper 1001, the totally-enclosed sampling test of the purified antibody is adopted as the above structure, thus the test effect and the quality of the purified antibody are improved, and the problems in the background technology are avoided at the same time, after the purified antibody sampling test is completed, the extraction cylinder 8 is taken out from the preparation of the purified antibody, then the water inlet 102 is opened to flow into the inner side of the frame body 1, then the servo motor is started again to drive the main shaft 2, the connecting plate 12 and the brush 1201 to rotate through the rotation of the main shaft 2, therefore, the hairbrush 1201 effectively scrapes and cleans the mesh plate 10 and the inner wall of the bottom of the frame body 1 in the rotating process, so that the inner wall of the bottom of the frame body 1 is cleaner in the cleaning process, and the problem that the whole sampling device for testing the purified antibody is polluted by the purified antibody remained in the sampling device when being used next time is solved.

The present invention is not limited by the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be equivalent replacement modes, and are all included in the protection scope of the present invention.

Claims

1. The utility model provides a sampling device for purification antibody detection usefulness, includes framework (1), main shaft (2), driven shaft (4) and brush (1201), its characterized in that: the middle part of the inner side of the frame body (1) is connected with a main shaft (2) in a bearing mode, a first bevel gear (3) is welded on the outer side of the main shaft (2), a driven shaft (4) is fixed on the right side of the first bevel gear (3), a second bevel gear (5) is welded on the outer side of the middle of the driven shaft (4), a short rod (6) is fixed on the inner side of the front of the second bevel gear (5), a rack (7) is arranged inside the right side of the frame body (1), a rotating plate (9) is meshed above the rack (7), an extracting barrel (8) penetrates through the inside of the right side of the frame body (1), a scraping plate (11) is fixed on the outer side of the main shaft (2), a screen plate (10) is further connected on the outer side of the lower portion of the main shaft (2) in a bearing mode, and a connecting plate (12) is welded on the left side of the main shaft (2); rack (7) inboard is provided with vaulting pole (701), and both ends all around vaulting pole (701) with framework (1) inside for welded fastening around to rack (7) right side welding has guide bar (702), and guide bar (702) right-hand member screwed connection has piston (703) moreover, guide way (801) have all been seted up to extraction section of thick bamboo (8) inner wall, and about guide way (801) and piston (703) constitute sharp sliding construction, and extraction section of thick bamboo (8) left side below has still seted up communicating pipe (802).

2. The sampling device of claim 1, wherein the sampling device comprises: test paper entry (101) have been seted up to framework (1) left side, and framework (1) top is installed water inlet (102) to framework (1) bottom is provided with delivery port (103).

3. A sampling device for use in detection of purified antibodies according to claim 2, wherein: the outer side of the short rod (6) is fixed with a rotary table (601), a pull rod (602) is welded in front of the rotary table (601), and the outer side of the pull rod (602) penetrates through the inner side of the rotary plate (9).

4. A sampling device for use in detection of purified antibodies according to claim 3, wherein: a through groove (901) is formed in the inner side of the front of the rotating plate (9), a rotating rod (902) is fixed on the inner side of the lower portion of the rotating plate (9), and the outer side of the lower portion of the rotating plate (9) is in a gear shape.

5. The sampling device of claim 4, wherein the sampling device comprises: the test paper (1001) is bonded above the screen (10), and the vertical center line of the screen (10) is overlapped with the vertical center line of the frame (1).

6. The sampling device of claim 5, wherein the sampling device comprises: the brush (1201) is installed on the left side of the connecting plate (12), and the outer side of the brush (1201) is in contact with the inner wall below the frame body (1).