CN213803776U

CN213803776U - Nucleic acid storage tube

Info

Publication number: CN213803776U
Application number: CN202022550471.3U
Authority: CN
Inventors: 黄震
Original assignee: Sentinall Biotechnologies Inc
Current assignee: Sentinall Biotechnologies Inc
Priority date: 2020-11-06
Filing date: 2020-11-06
Publication date: 2021-07-27
Anticipated expiration: 2030-11-06

Abstract

The utility model relates to a nucleic acid preservation tube, which comprises a tube body, wherein the tube body is a barrel-shaped cylinder structure, one end of the tube body is provided with an opening and is provided with a hollow interlayer, the hollow interlayer of the tube body is filled with a refrigerant, the opening end of the tube body is provided with a tube cap, the tube cap is provided with a thread through hole, a piston part is connected with the thread through hole through a thread, and the piston part is filled in a barrel-shaped inner cavity of the tube body; through the scheme, the technology of storing the nucleic acid extracting solution and reducing the oscillation risk of the nucleic acid extracting solution in the tube body under the condition of lower temperature is realized by adopting the scheme that the refrigerant is contained in the hollow interlayer of the tube body, the tube cap is covered on the tube body after the nucleic acid extracting solution is contained, and the gas in the tube body is extruded by utilizing the piston component.

Description

Nucleic acid storage tube

Technical Field

The utility model relates to a medical sample preserves technical field, especially relates to and is used for nucleic acid preservation equipment field, and specifically speaking is a nucleic acid preservation pipe.

Background

The nucleic acid is required to be stored and transported after being collected, a storage tube is required to be used in the storage and transportation processes, and meanwhile, in the storage and transportation processes, the nucleic acid solution stored in the storage tube is required to be prevented from shaking and the extracted nucleic acid solution is required to be stored at a lower temperature. The Chinese patent CN201920766115.X discloses a storage tube for increasing the amount of free nucleic acid, which comprises a storage tube cap, a rubber plug and a storage tube, wherein a sample separating agent is arranged inside the bottom end of the storage tube, an isolation medium blood separation gel is arranged above the sample separating agent, a free nucleic acid protective agent is arranged above the isolation medium blood separation gel, and the isolation medium blood separation gel and the free nucleic acid protective agent are both arranged inside the storage tube; the whole blood sample treated by the technology can improve the extraction quantity of free nucleic acid by 5-10 times; and is capable of inhibiting whole blood cell metabolism and maintaining the integrity of free nucleic acids for 14 days at room temperature; the processing method can be used for noninvasive prenatal gene detection and other related clinical examination applications based on free nucleic acid such as tumor screening and the like, and realizes the sample processing standardization based on the free nucleic acid examination, thereby improving the accuracy of the examination result.

The aforesaid fails to take precautions against earthquakes to the nucleic acid solution of gathering in the technique and swings the design, simultaneously, also fails to solve the technique that uses the nucleic acid solution that the protection tube has not just gathered at the collection nucleic acid in-process and provides lower temperature environment, to the aforesaid technical defect, the utility model provides a nucleic acid preservation pipe for solve the aforesaid technical defect.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a: the nucleic acid storage tube is used for solving the technical defects that the existing storage tube for nucleic acid extracting solution cannot reduce the oscillation of the nucleic acid solution caused by the air in the storage tube and cannot store the collected nucleic acid extracting solution at a lower temperature. The utility model discloses a setting up takes hollow interbedded tubbiness body, cap and piston component isotructure, adopts splendid attire refrigerant in the hollow intermediate layer of body to and cover the cap on the body after splendid attire nucleic acid extract and utilize the scheme that piston component extrudeed the gas in the body to realize preserving nucleic acid extract and reducing the technique that the nucleic acid extract took place to vibrate the risk in the body under the lower temperature condition. Adopt the utility model discloses can effectively realize afterwards preserving the nucleic acid extract under the lower temperature condition and reduce the technique that the nucleic acid extract took place to vibrate the risk in the body.

In order to realize the technical scheme, the utility model discloses a following technical scheme realizes:

the utility model provides a nucleic acid preservation pipe, includes the body, the one end of body is provided with the opening, the body is for having hollow interbedded tubbiness cylinder structure, the hollow interbedded intussuseption of body is filled with the refrigerant, the open end of body is provided with the pipe cap, be provided with the screw thread through-hole on the pipe cap, threaded connection has piston part in the screw thread through-hole, piston part fills in the tubbiness inner chamber of body.

In order to better realize the utility model discloses, as above-mentioned technical scheme's further optimization, the piston part includes screw rod, horizontal pole and piston, screw rod and pipe cap threaded connection, be provided with the axial through hole on the pole body of screw rod, the one end of screw rod is provided with the horizontal pole, and the piston is worn out to the other end, the one end that is close to the piston of screw rod is provided with hydrophobic gas molecular membrane.

As a further optimization of the technical scheme, an external thread is arranged on the outer wall of the opening end of the pipe body, an internal thread matched with the external thread is arranged on the pipe cap, and the external thread is in threaded connection with the pipe cap.

As a further optimization of the technical scheme, the outer wall of the pipe body is provided with a damping ring.

As a further optimization of the technical scheme, the outermost layer of the pipe body is an insulating layer.

Compared with the prior art, the utility model, following advantage and beneficial effect have:

the utility model discloses a setting up takes hollow interbedded tubbiness body, cap and piston component isotructure, adopts splendid attire refrigerant in the hollow intermediate layer of body to and cover the cap on the body after splendid attire nucleic acid extract and utilize the scheme that piston component extrudeed the gas in the body to realize preserving nucleic acid extract and reducing the technique that the nucleic acid extract took place to vibrate the risk in the body under the lower temperature condition.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:

fig. 1 is a schematic view of the overall structure of the present invention;

fig. 2 is a schematic plan view of the present invention.

The figure marks 1-tube, 2-refrigerant, 3-tube cap, 4-piston part, 5-damping ring, 41-screw, 42-cross bar, 43-piston, 44-hydrophobic gas molecular membrane.

Detailed Description

The present invention will be described in detail and with reference to the preferred embodiments of the present invention, but the present invention is not limited thereto.

Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it should be noted that the terms "first", "second", "third", etc. are used only for distinguishing the description, and are not intended to indicate or imply relative importance.

The terms "upper", "lower", "left", "right", "inner", "outer", and the like refer to orientations or positional relationships based on the drawings, or the orientations or positional relationships that are conventionally used to place the products of the present invention, and are used for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.

Furthermore, the terms "vertical" and the like do not require absolute perpendicularity between the components, but may be slightly inclined. Such as "vertical" merely means that the direction is relatively more vertical and does not mean that the structure must be perfectly vertical, but may be slightly inclined.

In the description of the present invention, it is also to be understood that the terms "disposed," "mounted," "connected," and the like are intended to be construed broadly unless otherwise specifically indicated and limited. For example, the connection can be fixed, detachable or integrated; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Example (b):

as a preferred embodiment, it is shown in FIG. 1 to FIG. 2;

the utility model provides a nucleic acid preservation pipe, includes body 1, the one end of body 1 is provided with the opening, body 1 is the tubbiness cylinder structure that has hollow intermediate layer, the hollow intermediate layer intussuseption of body 1 is filled with refrigerant 2, the open end of body 1 is provided with pipe cap 3, be provided with the screw thread through-hole on the pipe cap 3, threaded connection has piston 43 part 4 in the screw thread through-hole, piston 43 part 4 is filled in the tubbiness inner chamber of body 1.

In order to clearer and clear explanation the utility model discloses, take hollow interbedded tubbiness body 1, cap 3 and piston component 4 isotructure through the setting in this embodiment to splendid attire refrigerant 2 in the hollow intermediate layer of body 1, and cover cap 3 and utilize piston component 4 to realize preserving the nucleic acid extract and reducing the technique that the nucleic acid extract vibrates the risk in body 1 under the lower temperature condition with the scheme that the gas in body 1 was extruded on body 1 after the splendid attire nucleic acid extract.

In this embodiment, the refrigerant 2 may be a solvent capable of conducting a refrigerant, such as a sodium polyacrylate solution, GEL, or physiological saline.

The filling port is arranged on the pipe body, so that the filling agent can be increased, reduced or replaced.

In order to better realize the utility model discloses, as the further optimization of above-mentioned technical scheme, piston 43 part 4 includes screw rod 41, horizontal pole 42 and piston 43, screw rod 41 and pipe cap 3 threaded connection, be provided with the axial through-hole on the body of screw rod 41, the one end of screw rod 41 is provided with horizontal pole 42, and the piston 43 is worn out to the other end, the one end that is close to piston 43 of screw rod 41 is terminal to be provided with hydrophobic gas molecule membrane 44.

In order to more clearly and clearly illustrate the present invention, in the present embodiment, the piston 43 is a part 4 which is provided with a screw 41, a piston 43, and a hydrophobic gas molecular membrane 44, so that the air in the tank can be exhausted after the nucleic acid extracting solution is loaded and the piston 43 is twisted. Through setting up hydrophobic gas molecular membrane 44, the gas that makes piston 43 move down in-process production under the promotion of screw rod 41 can be followed the pipeline that is provided with hydrophobic gas molecular membrane 44 and discharged, sets up hydrophobic gas molecular membrane 44 simultaneously and can ensure again that the moisture in the nucleic acid extract can not spill over from the pipeline, and then has played the purpose of preserving the nucleic acid extract, has also reduced simultaneously because of the internal risk that leads to nucleic acid extract to rock in the jar body of air that exists of body 1.

As a further optimization of the technical scheme, an external thread is arranged on the outer wall of the opening end of the pipe body 1, an internal thread matched with the external thread is arranged on the pipe cap 3, and the external thread is in threaded connection with the pipe cap 3.

As a further optimization of the above technical solution, a damping ring 5 is arranged on the outer wall of the pipe body 1.

As a further optimization of the above technical scheme, the outermost layer of the pipe body 1 is a heat insulation layer.

For clearer and clear explanation the utility model discloses, as preferred embodiment, in this embodiment, the aim at that sets up damping ring 5 on the outer wall of body 1 is when needs have the nucleic acid extract to the splendid attire the utility model discloses when shifting or transporting, damping ring 5 can play certain shock attenuation effect to body 1, and then further reduces the risk that the nucleic acid extract rocked in body 1.

For better realization the utility model discloses, as preferred embodiment, as shown in fig. 1 ~ 2, the utility model discloses a work flow is: at first, will not splendid attire nucleic acid extract the utility model discloses place in cold-stored environment, use as needs the utility model discloses during splendid attire nucleic acid extract, just will the utility model discloses take out from cold-stored environment, open pipe cap 3 and take off pipe cap 3 and piston 43 part 4, in the nucleic acid extract splendid attire that will newly draw to body 1, treat the splendid attire completion, just put into body 1 with piston 43, slowly impress piston 43 in to body 1, discharge in the through-hole of screw rod 41 in unnecessary air is followed gradually in the body 1 this moment, after pipe cap 3 and body 1's the mouth of pipe contact, slowly twist pipe cap 3, cause pipe cap 3 and body 1 threaded connection, twist horizontal pole 42, make screw rod 41 continue to promote piston 43 motion, and finally make piston 43 be provided with the liquid level contact of one side and the nucleic acid extract of hydrophobic gas molecular membrane 44, finally, realize preserving nucleic acid extract and reducing nucleic acid extract and taking place the skill of risk of shaking in body 1 under the lower temperature condition and vibrate the skill And (4) performing the operation.

Through the scheme, the technology of storing the nucleic acid extracting solution and reducing the oscillation risk of the nucleic acid extracting solution in the tube body under the condition of lower temperature is realized by adopting the scheme that the refrigerant is contained in the hollow interlayer of the tube body, the tube cap is covered on the tube body after the nucleic acid extracting solution is contained, and the gas in the tube body is extruded by utilizing the piston component.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A nucleic acid storage tube, characterized in that: the cooling device comprises a pipe body (1), wherein an opening is formed in one end of the pipe body (1), the pipe body is of a barrel-shaped cylinder structure with a hollow interlayer, a refrigerant (2) is filled in the hollow interlayer of the pipe body (1), a pipe cap (3) is arranged at the open end of the pipe body (1), a threaded through hole is formed in the pipe cap (3), a piston component (4) is connected to the threaded through hole in a threaded mode, and the piston component (4) is filled in a barrel-shaped inner cavity of the pipe body (1).

2. A nucleic acid storage tube according to claim 1, wherein: piston part (4) include screw rod (41), horizontal pole and piston, screw rod (41) and pipe cap (3) threaded connection, be provided with axial through hole on the pole body of screw rod (41), the one end of screw rod (41) is provided with horizontal pole (42), and piston (43) are worn out to the other end, the one end that is close to piston (43) of screw rod (41) is provided with hydrophobic gas molecular membrane (44).

3. A nucleic acid storage tube according to claim 1, wherein: the pipe is characterized in that an external thread is arranged on the outer wall of the opening end of the pipe body (1), an internal thread matched with the external thread is arranged on the pipe cap (3), and the external thread is in threaded connection with the pipe cap (3).

4. A nucleic acid storage tube according to claim 1, wherein: and a damping ring (5) is arranged on the outer wall of the pipe body (1).

5. A nucleic acid storage tube according to claim 1, wherein: the outermost layer of the pipe body is an insulating layer.