CN213771994U - A fermentation cylinder for production of many myxobacillus - Google Patents
A fermentation cylinder for production of many myxobacillus Download PDFInfo
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- CN213771994U CN213771994U CN202022858304.5U CN202022858304U CN213771994U CN 213771994 U CN213771994 U CN 213771994U CN 202022858304 U CN202022858304 U CN 202022858304U CN 213771994 U CN213771994 U CN 213771994U
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 41
- 241000194105 Paenibacillus polymyxa Species 0.000 claims abstract description 23
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Images
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A fermentation tank for producing bacillus polymyxa comprises a shell, a tank body arranged in the shell and supporting legs arranged at the bottom of the shell, wherein the tank body is of a vertically arranged closed cylindrical structure; an adjusting hole with the same diameter as the outer diameter of the tank body is arranged in the center of the top of the shell, the tank body can penetrate through the adjusting hole to move up and down, an electric heating sheet is arranged on the side wall inside the shell, and a water inlet pipe and a water outlet pipe communicated to the outside are respectively arranged at the top end and the bottom end of the shell; the utility model discloses well jar body can run through the regulation hole and reciprocate to area of contact through jar body and water bath adjusts its temperature rapidly, thereby solves the problem that the temperature regulation is not convenient for of water bath heating, and the mode of using water bath heating also can let each part of the jar body heat up simultaneously, keeps the temperature on the jar body evenly unanimous all the time, can protect inside bacterium better, makes its normal growth develop.
Description
Technical Field
The utility model relates to a bacterial culture technique and equipment field, concretely relates to fermentation cylinder for production of bacillus polymyxa.
Background
The bacillus polymyxa is one of bacillus, is widely distributed in soil and putrefactive organic matters, and is easy to propagate in the hay leachate, so the bacillus polymyxa is named. The bacillus polymyxa has two growth periods of a spore dormancy period and a reproductive growth period, and can enter the spore dormancy period under unfavorable environments such as severe growth environment and nutrient deficiency, and form spores which have strong stress resistance and can survive under polar environments such as high temperature, acid and alkali, so that the bacillus polymyxa is suitable for the environment to survive. Once the environment becomes suitable for growth and sufficient nutrition, the spores automatically enter the reproductive growth period and grow into the bacillus polymyxa again.
Active substances such as subtilin, polymyxin, nystatin, gramicidin and the like generated in the growth process of the bacillus polymyxa have obvious inhibiting effect on pathogenic bacteria or pathogenic bacteria conditioned by endogenous infection. The bacillus polymyxa rapidly consumes free oxygen in the intestinal tract, causes hypoxia in the intestinal tract, promotes the growth of beneficial anaerobic bacteria, and indirectly inhibits the growth of other pathogenic bacteria. Stimulating the growth and development of immune organs of animals (human bodies), activating T, B lymphocytes, increasing the levels of immunoglobulin and antibody, enhancing the cellular immunity and humoral immunity functions, and improving the immunity of the population. The bacillus polymyxa self-synthesizes enzymes such as alpha-amylase, protease, lipase, cellulase and the like, and plays a role together with digestive enzymes in an animal body (human body) in the digestive tract.
At present, fermentation technology is generally used for carrying out standardized production and cultivation on the bacillus polymyxa, so that the bacillus polymyxa is obtained in large quantity for use in the aspect of biomedicine. The bacillus polymyxa needs to be kept at a certain temperature during growth, and a commonly used fermentation tank is generally heated electrically, but the problem of overhigh local temperature exists in the electric heating, so that the bacillus polymyxa possibly dies at local high temperature; therefore, a water bath heating mode is provided, and the constant temperature state can be better kept. However, the fermentation tank heated by the water bath has a certain problem, because the specific heat capacity of water is large, when the temperature needs to be adjusted, the temperature is changed very slowly, so that the adjustment is very insensitive, and the fermentation tank is not suitable for being used under the condition that the temperature needs to be changed frequently, so that the fermentation tank which can be integrally kept at the constant temperature for a long time and can be quickly adjusted in temperature is needed.
SUMMERY OF THE UTILITY MODEL
To the not enough that exists among the prior art, the utility model provides a fermentation cylinder for production of bacillus polymyxa for solve current water bath heating formula fermentation cylinder because the temperature change of water is very slow, lead to adjusting very insensitive, be unsuitable in the problem that the condition of often needing to change the temperature used.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a fermentation tank for producing bacillus polymyxa comprises a shell, a tank body arranged in the shell and supporting legs arranged at the bottom of the shell, wherein the shell is of a hollow closed structure, the tank body is just arranged at the center position in the shell, so that the tank body is not in mutual contact with the inner side surfaces of the shell, and the tank body is of a vertically arranged closed cylindrical structure;
an adjusting hole with the diameter the same as the outer diameter of the tank body is formed in the center of the top of the shell, the tank body can penetrate through the adjusting hole to move up and down, a support is further arranged on the top of the tank body, horizontal connecting plates are symmetrically mounted on two sides of the support, symmetrical hydraulic rods are arranged on two sides of the top of the shell, and the output end of each hydraulic rod is fixed to the bottom of the corresponding connecting plate;
the electric heating plate is arranged on the side wall inside the shell, a water inlet pipe and a water outlet pipe communicated to the outside are respectively arranged at the top end and the bottom end of the shell, the water inlet pipe is connected to a water source, a first cabin door capable of being opened and closed is arranged at the bottom of the tank body, a second cabin door capable of being opened and closed is arranged at the bottom of the shell, the first cabin door and the second cabin door are coaxially arranged, and the area of the second cabin door is larger than that of the first cabin door.
Further, the coaxial pivot that is provided with of jar internal portion, the top that jar body and shell were run through to the pivot upper end extends to the outside to link to each other with the motor of fixed mounting on the support, the part that the pivot is located jar internal portion extends to jar body bottom, still be provided with continuous helical blade in the pivot.
Furthermore, the pivot is telescopic rod structure, including canned paragraph and activity section, wherein the canned paragraph is located the shell top, and the activity section is located shell and jar internal portion, the canned paragraph links to each other with the motor.
Furthermore, still be provided with the baffle on the jar internal side, the baffle encircles distribution around jar internal wall, and the baffle does not influence helical blade's rotation.
Furthermore, the baffle is provided with a plurality of layers from top to bottom along the inner wall of the tank body, and the baffle is arranged in a downward inclined mode.
Furthermore, the first cabin door is an outward opening single door body, and the second cabin door is a double door body with two opened sides.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the utility model is provided with a shell and a tank body positioned in the shell, wherein the tank body can penetrate through the adjusting hole to move up and down, so that the temperature of the tank body can be rapidly adjusted through the contact area between the tank body and the water bath, and the problem that the temperature is not convenient to adjust by water bath heating is solved;
2. the utility model discloses the mesochite is closed structure, can soak the jar body in aqueous through the inlet tube water that adds, then heat to the water of inside with the electric heat piece, thereby heat the jar body of inside through the water bath, this kind of water bath heating's mode can let each part of the jar body heat up simultaneously, keep the temperature on the jar body evenly unanimous all the time, can not have the local too high condition, can protect the bacterium of inside better, make its normal growth develop;
3. the utility model discloses a be provided with continuous helical blade in the pivot, can play the effect that promotes the transport when rotating to the accumulational thallus that will be located jar body bottom promotes jar body top on one side the stirring, when its whereabouts, mixes with other thalli and the culture solution at top again, thereby has promoted the misce bene degree of jar internal portion bacterium and culture solution, is favorable to the normal growth of bacterium.
Drawings
FIG. 1 is a schematic diagram of the present invention;
FIG. 2 is a schematic view of the tank and the baffle plate of the present invention;
in the figure: 1. a housing; 2. a tank body; 3. a rotating shaft; 4. a helical blade; 5. a baffle plate; 6. a support; 7. a motor; 8. a connecting plate; 9. a hydraulic lever; 11. an electric heating sheet; 12. a second door; 13. a water inlet pipe; 14. a water outlet pipe; 15. adjusting the holes; 21. a first door; 22. a feed tube; 31. a fixed section; 32. and (4) an active segment.
Detailed Description
The technical solution of the present invention will be further explained with reference to the accompanying drawings and embodiments.
Example (b):
as shown in figure 1, the utility model provides a fermentation cylinder for production of bacillus polymyxa, including shell 1, set up at the inside jar body 2 of shell 1 and set up the supporting legs in shell 1 bottom, wherein the supporting legs supports shell 1 subaerial to let jar internal portion of body 2 add the bacterium and cultivate.
In this embodiment, the inside hollow closed structure that is of shell 1, jar body 2 is through setting up in the inside of shell 1, and jar body 2 and the medial surface of shell 1 all do not contact each other, form the suspended structure. The electric heating plate 11 is arranged on the side wall inside the shell 1, the top end and the bottom end of the shell 1 are respectively provided with a water inlet pipe 13 and a water outlet pipe 14 communicated to the outside, and the water inlet pipe 13 is connected to a water source. The tank body 2 can be soaked in water by adding water through the water inlet pipe 13, then the water inside the tank body is heated by the electric heating sheet 11, and after fermentation is completed, the water is discharged through the water outlet pipe 14 and then discharged. Therefore, the tank body 2 in the tank body 2 is heated through the water bath, each part of the tank body 2 can be heated simultaneously by the water bath heating mode, the temperature on the tank body 2 is kept uniform and consistent all the time, and the local overhigh condition is avoided.
In the embodiment, an adjusting hole 15 is further formed in the center of the top of the shell 1, the diameter of the adjusting hole 15 is matched with the outer diameter of the tank body 2, so that the tank body 2 can just penetrate through the adjusting hole 15 to move up and down, a support 6 is further arranged on the top of the tank body 2, horizontal connecting plates 8 are symmetrically mounted on two sides of the support 6, symmetrical hydraulic rods 9 are vertically arranged on the edge of the top of the shell 1, and the output end of each hydraulic rod 9 is fixed to the bottom of each connecting plate 8; through jar body 2 and the up-and-down movement of adjusting hole 15 is run through under the drive of hydraulic stem 9, can adjust its temperature rapidly through the area of contact of jar body 2 and water bath to solve the water bath heating and be not convenient for temperature regulation's problem.
Further in this example, jar body 2 is the closed cylinder of vertical setting, jar body 2 is inside coaxial being provided with pivot 3, 3 upper ends of pivot run through jar body 2 and shell 1 top and extend to the outside to link to each other with motor 7 of fixing on support 6, the part that pivot 3 is located jar body 2 inside extends to jar body 2 bottom, still be provided with continuous helical blade 4 in the pivot 3. Through continuous helical blade 4, can play the effect that promotes the transport when rotating to promote the top of jar body 2 with the stirring of the accumulational thalli that is located jar body 2 bottom, when its whereabouts, mix with other thalli and the culture solution at top again, thereby promoted the misce bene degree of jar internal portion bacterium of body 2 and culture solution.
It should be noted that an openable and closable first door 21 is arranged at the bottom of the tank body 2, an openable and closable second door 12 is arranged at the bottom of the outer shell 1, the first door 21 and the second door 12 are coaxially arranged, and the area of the second door 12 is larger than that of the first door 21. The fermentation and the discharging work can be respectively carried out by opening and closing the first door 21 and the second door 12. Preferably, the first door 21 is an electrically controlled automatic outward-opening single door body, and the second door 12 is a double door body with two sides opened, so that adhesion of viscous materials on the first door 21 can be avoided, and influence on quality of discharged bacteria caused by mixing of heated water adhered to the second door 12 can also be avoided. Correspondingly, the top of the tank body 2 is also provided with a feed pipe 22, and a mixture of bacteria and culture solution can be added through the feed pipe 22.
In a preferred scheme, the rotating shaft 3 is of a telescopic rod structure and comprises a fixed section 31 and a movable section 32, wherein the fixed section 31 is located at the top end of the shell 1, the movable section 32 is located inside the shell 1 and the tank body 2, the fixed section 31 is connected with the motor 7, because the bracket 6 is already arranged above the tank body 2, the bracket 6 can be adjusted to be arranged at the axial line position of the tank body, then the motor 7 is fixedly arranged at the top of the bracket 6, and an opening is formed in the bottom of the bracket 6 for the fixed section 31 to pass through. The position of the helical blade 4 on the movable section 32 can be controlled through the telescopic rod structure, so that the area needing stirring can be better adjusted, and the electric telescopic rod structure is preferably adopted in the embodiment. Also can raise helical blade 4 in the in-process of feeding and ejection of compact simultaneously, the ejection of compact of bottom material after piling up and fermenting in jar body 2 bottom of material when avoiding its influence feeding.
As shown in fig. 2, in a further embodiment of the present embodiment, a baffle 5 is further disposed on an inner side surface of the tank 2, the baffle 5 is distributed around an inner wall of the tank 2, the rotation of the helical blade 4 is not affected by the baffle 5, and the falling speed of the material lifted above the tank 2 can be delayed by the baffle 5, so that the material is more fully mixed with the culture medium on the top. Preferably, the baffle 5 is provided with a plurality of layers up and down along the inner wall of the tank body 2, and the baffle 5 is a convex frustum structure, preferably a square frustum in the embodiment, and the top surface of the frustum is a concave arc; the arrangement mode enables the materials to be blocked layer by layer in the falling process, the falling speed of the materials is further delayed, meanwhile, partial materials are prevented from being accumulated on the baffle 5, dead corners do not exist on the bottom surface of the baffle, and the materials are prevented from being blocked at the dead corners below the baffle 5.
Finally, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the present invention can be modified or replaced by other means without departing from the spirit and scope of the present invention, which should be construed as limited only by the appended claims.
Claims (6)
1. A fermentation cylinder for production of bacillus polymyxa which characterized in that: the tank body is arranged in the shell, the supporting legs are arranged at the bottom of the shell, the shell is of a hollow closed structure, the tank body is just arranged at the center position in the shell, so that the tank body is not in mutual contact with the inner side surfaces of the shell, and the tank body is of a vertically arranged closed cylindrical structure;
an adjusting hole with the diameter the same as the outer diameter of the tank body is formed in the center of the top of the shell, the tank body can penetrate through the adjusting hole to move up and down, a support is further arranged on the top of the tank body, horizontal connecting plates are symmetrically mounted on two sides of the support, symmetrical hydraulic rods are arranged on two sides of the top of the shell, and the output end of each hydraulic rod is fixed to the bottom of the corresponding connecting plate;
the electric heating plate is arranged on the side wall inside the shell, a water inlet pipe and a water outlet pipe communicated to the outside are respectively arranged at the top end and the bottom end of the shell, the water inlet pipe is connected to a water source, a first cabin door capable of being opened and closed is arranged at the bottom of the tank body, a second cabin door capable of being opened and closed is arranged at the bottom of the shell, the first cabin door and the second cabin door are coaxially arranged, and the area of the second cabin door is larger than that of the first cabin door.
2. The fermentor for use in production of bacillus polymyxa according to claim 1, wherein: the internal portion of jar is coaxial to be provided with the pivot, the top that jar body and shell were run through to the pivot upper end extends to the outside to link to each other with the motor of fixed mounting on the support, the pivot is located the internal portion of jar and extends to jar body bottom, still be provided with continuous helical blade in the pivot.
3. The fermentor for use in production of bacillus polymyxa according to claim 2, wherein: the rotating shaft is of a telescopic rod structure and comprises a fixed section and a movable section, wherein the fixed section is located at the top end of the shell, the movable section is located inside the shell and the tank body, and the fixed section is connected with the motor.
4. The fermentor for use in production of bacillus polymyxa according to claim 1, wherein: still be provided with the baffle on the jar body medial surface, the baffle encircles distribution around jar internal wall, and the baffle does not influence helical blade's rotation.
5. The fermentor for use in production of bacillus polymyxa according to claim 4, wherein: the baffle is provided with a plurality of layers from top to bottom along the inner wall of the tank body, and the baffle is arranged in a downward inclined mode.
6. The fermentor for use in production of bacillus polymyxa according to claim 1, wherein: the first cabin door is an outward opening single door body, and the second cabin door is a double door body with two opened sides.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022858304.5U CN213771994U (en) | 2020-12-02 | 2020-12-02 | A fermentation cylinder for production of many myxobacillus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022858304.5U CN213771994U (en) | 2020-12-02 | 2020-12-02 | A fermentation cylinder for production of many myxobacillus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213771994U true CN213771994U (en) | 2021-07-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022858304.5U Expired - Fee Related CN213771994U (en) | 2020-12-02 | 2020-12-02 | A fermentation cylinder for production of many myxobacillus |
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| Country | Link |
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| CN (1) | CN213771994U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117797498A (en) * | 2024-03-01 | 2024-04-02 | 连云港贵科药业有限公司 | Reduced pressure distillation device for capecitabine intermediate |
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2020
- 2020-12-02 CN CN202022858304.5U patent/CN213771994U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117797498A (en) * | 2024-03-01 | 2024-04-02 | 连云港贵科药业有限公司 | Reduced pressure distillation device for capecitabine intermediate |
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Granted publication date: 20210723 |