CN213736402U

CN213736402U - Sample storage device

Info

Publication number: CN213736402U
Application number: CN202022866021.5U
Authority: CN
Inventors: 许波; 许重远; 宿爱山; 古安城; 姚香草; 王艳芳
Original assignee: Southern Hospital Southern Medical University
Current assignee: Southern Hospital Southern Medical University
Priority date: 2020-12-03
Filing date: 2020-12-03
Publication date: 2021-07-20
Anticipated expiration: 2030-12-03

Abstract

The utility model discloses a sample storage device, which comprises a freezing box and at least two freezing plates, wherein the freezing box is arranged in an ultra-low temperature refrigerator and comprises a box body with a first cavity and a box cover capable of shielding the opening end of the first cavity; every cryopreserved board has at least one and is used for placing the second cavity of cryopreserved pipe, and every cryopreserved board detachable sets up in first cavity, and cryopreserved board passes through positioning mechanism and injects in first cavity. The utility model discloses set up the freezing board that detachable set up in the first cavity, the freezing box is placed in the ultra-low temperature refrigerator, and during the use, the operator puts into a freezing board with the freezing pipe after adding the sample earlier, and then put into the freezing box draw-in groove with the freezing board and can, need not take the freezing box repeatedly, and easy operation can avoid the sample in the freezing box to take place the overtemperature condition again; the handle outside of lid is the cotton layer, packs the foam material layer or the cotton layer of pearl that the thermal conductivity is low in the hand (hold), is prevented by frostbite when the operator draws the lid, and is safe and the practicality is high.

Description

Sample storage device

Technical Field

The utility model belongs to blood sample preserves the field, more specifically relates to sample storage device.

Background

The current common methods are: the centrifuged serum/plasma sample is firstly put into a freezing tube, then the freezing tube is put into a plastic box with holes, and finally the plastic box is put into an ultra-low temperature refrigerator with the temperature of minus 80 ℃. Particularly, in a phase I clinical test or a drug bioequivalence test of a drug, at least 11-12 sampling time points exist at the time point of blood collection, and each time point usually has a sample size of about 12-24 persons. In the whole test process, due to the fact that sampling time points are multiple, the plastic box needs to be taken from the ultralow-temperature refrigerator repeatedly, and due to the fact that the temperature of the plastic box is extremely low, operators are easily frostbitten. The distance between the freezing storage tubes in the plastic box is small, so that the samples are inconvenient to take and check.

The ultra-low temperature refrigerator has a large temperature difference between the inside and the outside (generally, the temperature in the ultra-low temperature refrigerator is about minus 80 ℃, and the outside temperature is about 25 ℃), and the sample amount in the cryopreservation tube is small. After the plastic box is taken out of the ultra-low temperature refrigerator, the frozen sample in the plastic box is easily redissolved or the storage temperature exceeds the storage temperature specified by the test scheme, namely, the overtemperature phenomenon occurs, when the overtemperature phenomenon occurs to the sample, the accuracy of the detection of the drug or the metabolite thereof in the sample can be influenced, and particularly, in the phase I clinical test or the drug bioequivalence test of the drug, a plurality of samples need to be frozen at each sampling time point. The sample is put into the plastic box for a long time, and the overtemperature phenomenon is easy to occur when the sample in the plastic box is at room temperature for a long time, so that the test quality is influenced.

SUMMERY OF THE UTILITY MODEL

The utility model discloses a main aim at provides a sample storage device, convenient operation avoids freezing the case and takes out and lead to freezing the interior sample of case and take place the overtemperature prote phenomenon from ultra-low temperature refrigerator.

According to the utility model discloses an aspect provides sample storage device, include:

the cryopreservation box is arranged in the ultra-low temperature refrigerator and comprises a box body with a first cavity and a box cover capable of shielding the opening end of the first cavity;

at least two freeze and deposit the board, every freeze and deposit the board and have at least one second cavity that is used for placing the pipe that freezes, every freeze and deposit board detachable and set up in first cavity, it passes through positioning mechanism and injects in first cavity to freeze and deposits the board.

In a specific embodiment of the present invention, the positioning mechanism includes a card strip and a card slot, the card strip is disposed at two ends of the freezing plate, and the card slot is disposed at two opposite inner walls of the first cavity at an interval.

The utility model discloses a specific embodiment, the cryopreserving board includes bottom plate and a plurality of cryopreserving check, be equipped with the constant head tank that is used for placing the cryopreserving check on the bottom plate.

In a specific embodiment of the present invention, the number of the freezing plates is plural, wherein the colors of the freezing plates are at least 2.

In a specific embodiment of the present invention, the upper portion of the inner wall of the first cavity is provided with a first slope, and the edge of the box cover is provided with a second slope adapted to the first slope.

In a particular embodiment of the present invention, the box body comprises an inner box body wall and an outer box body wall, and a first thermal insulation material layer is filled between the inner box body wall and the outer box body wall.

In a specific embodiment of the present invention, the outer surface of the box body is wrapped with a second thermal insulation material layer.

In a specific embodiment of the present invention, the upper end surface of the box cover is provided with a handle, the outside of the handle is wrapped with a cotton layer, and the inside of the handle is filled with a foam material layer or a pearl cotton layer.

In a particular embodiment of the invention, the cover comprises a first layer, a second layer and a third layer of insulating material located between the first layer and the second layer.

The utility model discloses a technical scheme has following advantage or one of beneficial effect at least among the above-mentioned technical scheme: the utility model discloses set up the freezing board that detachable set up in the first cavity, the freezing box is placed in the ultra-low temperature refrigerator, and during the use, the operator puts into a freezing board with the freezing pipe after adding the sample earlier, and then put into the freezing box draw-in groove with the freezing board and can, need not take the freezing box repeatedly, and easy operation can avoid the sample in the freezing box to take place the overtemperature condition again; the handle outside of lid is the cotton layer, packs the foam material layer or the cotton layer of pearl that the thermal conductivity is low in the hand (hold), is prevented by frostbite when the operator draws the lid, and is safe and the practicality is high.

Drawings

The present invention will be further described with reference to the accompanying drawings and examples;

figure 1 is a cross-sectional view of a first embodiment of the invention;

fig. 2 is a plan view of the first embodiment of the present invention.

Detailed Description

Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the accompanying drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.

In the description of the present invention, it should be understood that the orientation or positional relationship indicated with respect to the orientation description, such as up, down, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

In the description of the present invention, a plurality of means are one or more, a plurality of means are two or more, and the terms greater than, less than, exceeding, etc. are understood as not including the number, and the terms greater than, less than, within, etc. are understood as including the number. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more features.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the term "connected" is to be interpreted broadly, and may be, for example, a fixed connection or a movable connection, a detachable connection or a non-detachable connection, or an integral connection; may be mechanically connected, may be electrically connected or may be in communication with each other; they may be directly connected or indirectly connected through intervening media, or may be connected through one or more other elements or indirectly connected through one or more other elements or in an interactive relationship between two elements.

The following disclosure provides many different embodiments or examples for implementing different aspects of the invention.

Referring to fig. 1 to 2, the sample storage device includes:

the cryopreservation box 11 is arranged in the ultra-low temperature refrigerator, the cryopreservation box 11 is in a hollow cuboid shape, and the cryopreservation box 11 comprises a box body with a first cavity and a box cover 14 capable of shielding the open end of the first cavity;

at least two freezing plates 12, every freezing plate 12 has at least one second cavity 22 that is used for placing freezing pipe 19, and the internal diameter of second cavity 22 slightly is greater than freezing pipe 19's external diameter to prevent freezing pipe 19 slope, every freezing plate 12 detachable sets up in the first cavity, freezing plate 12 is injectd in the first cavity through positioning mechanism.

The utility model discloses set up the freezing plate 12 of detachable setting in the first cavity, freezing box 11 is placed in the ultra-low temperature refrigerator, and during the use, the operator puts into a freezing plate 12 with freezing pipe 19 after adding the sample earlier, and then put freezing plate 12 into freezing box 11 draw-in groove, need not take freezing box 11 repeatedly, and easy operation is convenient and can avoid freezing the sample in the box 11 and take place the overtemperature condition; the outside of the handle of the box cover 14 is a cotton cloth layer, and a foam material layer or a pearl cotton layer with low heat conductivity is filled in the handle, so that the freezing injury of an operator when the box cover 14 is taken is avoided, and the safety and the practicability are high.

The utility model discloses an embodiment, positioning mechanism includes card strip 16 and draw-in groove 17, card strip 16 sets up at the both ends of freezing board 12, draw-in groove 17 interval sets up two relative inner walls in first cavity. When the operator will freeze and deposit board 12 and put into and freeze and deposit box 11, freeze the card strip 16 that deposits board 12 both ends and correspond the draw-in groove 17 of two inner walls of first cavity respectively, card strip 16 is down along draw-in groove 17, realizes freezing the location of depositing board 12, and the operator location of being convenient for is placed and is frozen and deposit board 12, makes each freezing board 12 relatively fixed in freezing box 11 of depositing, can not mix and be in the same place. The operator moves the freezing plate 12 upward, so that the card strip 16 moves upward along the card slot 17, and when the card strip 16 is separated from the card slot 17, the operator can take out the freezing plate 12.

The utility model discloses an embodiment, the freezing plate 12 includes bottom plate 20 and a plurality of freezing check 18, be equipped with the constant head tank that is used for placing freezing check 18 on the bottom plate 20. The bottom plate 20 is provided with two vertical plates, the freezing storage grid 18 is arranged between the two vertical plates, and the clamping strip 16 is arranged on the upper parts of the vertical plates. Freezing check 18 lower part of depositing is equipped with the first boss 21 that the external diameter is less than the external diameter of freezing check body, and first boss 21 inlays to make freezing check 18 of depositing fixed behind the constant head tank, and two adjacent outer surfaces of freezing between the check 18 of depositing are hugged closely to drop from bottom plate 20 when preventing freezing check 18 transport. The freezing check 18 of depositing can dismantle the setting, is convenient for change the freezing check 18 that damages. The freezing grids 18 are embedded in the positioning grooves of the same bottom plate 20 and then are arranged linearly. It should be noted that the aforementioned outer diameter may be a diameter, or may be a distance between two opposite sidewalls of the object.

It should be noted that the two freezing grids 18 are spliced by a mosaic structure. Wherein the gomphosis structure is including setting up the first recess that freezes the first side of depositing check 18 and setting up the first lug that freezes the second side of depositing check 18, and first side is relative with the second side, and one of them freezes the first lug of depositing check and inlays the second recess to another freezing second of depositing check, realizes two 18 concatenations of freezing of depositing check.

In one embodiment of the present invention, the number of the freezing plates 12 is multiple, wherein the colors of the freezing plates 12 are at least 2. The freeze plate 12 is made of a colored plastic material. Usually, a plurality of samples for clinical tests are placed in one ultra-low temperature refrigerator, and an operator can distinguish different clinical test items by the color of the freezing plate 12, wherein the color of the freezing plate 12 is the same as that of the same clinical test item, and the color of the freezing plate 12 is different from that of different clinical test items; therefore, the samples of different clinical tests are effectively prevented from being mixed together, and the authenticity and the effectiveness of the clinical tests are ensured.

In one embodiment of the present invention, the upper portion of the inner wall of the first cavity is provided with a first inclined portion 23, and the edge of the box cover 14 is provided with a second inclined portion 24 adapted to the first inclined portion 23. When the box body is covered by the box cover 14, the first inclined part 23 and the second inclined part 24 are matched to play a role in positioning, and the box cover 14 and the box body are tightly plugged to play a certain heat preservation role.

The utility model discloses an embodiment, the box body includes box body inner wall and box body outer wall, it has first heat preservation material layer to fill between box body inner wall and the box body outer wall. When the ultra-low temperature refrigerator door is opened for a long time or frequently, the temperature in the low temperature refrigerator is excessively higher than the temperature for sample storage, the heat preservation effect of the first heat preservation material layer can effectively maintain the temperature for storing the sample in the freezing storage box 11, and the over-temperature phenomenon is avoided. The thermal insulation material of the first thermal insulation material layer may be polyurethane foam.

In one embodiment of the present invention, the outer surface of the box body is wrapped with a second thermal insulation material layer. The second heat-insulating material layer can be a combination of pearl wool and aluminum foil tinfoil, and the aluminum foil tinfoil is positioned on one side, close to the outer surface of the box body, of the second heat-insulating material layer, so that the process of heat exchange can be effectively slowed down, and a good heat-insulating effect is achieved. The pearl wool is located the outside of second insulation material layer, is prevented by the frostbite when the operator takes out the box body, and is safe and the practicality is high.

The utility model discloses an embodiment, the up end of lid 14 is equipped with the handle, and the parcel has the cotton layer outside the handle, and the inside packing of handle has foam material layer or the cotton layer of pearl, is frostbite when avoiding the operator to draw lid 14.

In one embodiment, the cover 14 includes a first layer, a second layer, and a third layer of insulating material between the first layer and the second layer. The third insulating material layer provides the insulating effect to the box cover 14. Preferably, the third thermal insulation material layer is a polyurethane foam layer. Of course, in order to facilitate the operator to observe the state of the cryopreservation tube 19 in the box body, an observation window penetrating through the first layer, the third heat-insulating material layer and the second layer can be arranged.

It should be noted that the box cover 14 may also adopt a double-layer vacuum transparent organic glass to replace the first layer, the third insulating material layer and the second layer, so that the operator can observe the state of the freezing tube 19 in the box body.

While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: various changes, modifications, substitutions and alterations can be made to the embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A sample storage device, comprising:

2. The specimen storage device of claim 1, wherein the positioning mechanism comprises a card strip disposed at both ends of the cryopreservation plate and a card slot disposed at two opposing inner walls of the first cavity at an interval.

3. The specimen storage device of claim 1, wherein the cryopreservation plate comprises a bottom plate and a plurality of cryopreservation cells, and the bottom plate is provided with positioning grooves for placing the cryopreservation cells.

4. The sample storage device of claim 1, wherein the number of freeze plates is multiple, wherein the freeze plates are at least 2 colors.

5. The sample storage device as claimed in claim 1, wherein the first cavity has a first inclined portion at an upper portion of an inner wall thereof, and the lid has a second inclined portion at an edge thereof to be fitted to the first inclined portion.

6. The sample storage device of claim 1, wherein the cartridge comprises an inner cartridge wall and an outer cartridge wall, and wherein a first layer of insulating material is filled between the inner cartridge wall and the outer cartridge wall.

7. The sample storage device of claim 1 or 6, wherein the outer surface of the cassette is wrapped with a second layer of insulating material.

8. The specimen storage device of claim 1, wherein the lid has a handle at an upper end thereof, the handle is wrapped with a cotton layer, and the handle is filled with a foam layer or a pearl cotton layer.

9. The sample storage device of claim 1, wherein the lid comprises a first layer, a second layer, and a third layer of insulating material between the first layer and the second layer.