CN213600722U - Immunohistochemical antibody smearing device - Google Patents
Immunohistochemical antibody smearing device Download PDFInfo
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- CN213600722U CN213600722U CN202022597964.2U CN202022597964U CN213600722U CN 213600722 U CN213600722 U CN 213600722U CN 202022597964 U CN202022597964 U CN 202022597964U CN 213600722 U CN213600722 U CN 213600722U
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- container
- immunohistochemical
- pressurizing
- opening
- material distribution
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Abstract
The utility model relates to an immunohistochemical antibody smearing device, which comprises a glass slide for placing immunohistochemical substances; the material distribution container is arranged on the upper surface of the glass slide, an opening of the material distribution container is arranged downwards, and the opening of the material distribution container is arranged in a plane shape; the sealing washer is fixedly connected to the opening of the material distributing container; a pressurizing mechanism for pressurizing an inner space of the material distribution container; the pressure relief mechanism is used for relieving the pressure in the inner space of the cloth container; and the pressing mechanism is used for pressing the cloth container. The utility model discloses can reach effectively fast and carry out even coating to immunohistochemical thing, and can prevent effectively that immunohistochemical thing from being stained with to effectively promote the controllability of experiment by a wide margin.
Description
Technical Field
The utility model relates to an even ware is smeared to immunohistochemical antibody, in its mainly used immunohistochemical antibody experimentation, evenly coat antibody and tissue.
Background
In the immunohistochemical experiment process, tissues are usually placed on a glass slide, then antibodies are dripped on the tissues, and the dripped antibodies cannot be uniformly distributed on the tissues due to the action of water molecule tension.
The traditional solution is that an experiment operator directly uses a gun head for dropwise adding the antibody to uniformly coat the antibody and the tissues, the antibody and the tissues cannot be uniformly coated by the coating mode, the gun head is easy to adhere to the antibody and the tissues, and the operation difficulty is very high. Many laboratories have since begun to use immunohistochemical antibody applicators similar to the brush type, brush the antibody and tissue through a brush and through an external sleeve to prevent spillage. Thus, although the coating uniformity of the antibodies and tissues is improved to a certain extent and the operation difficulty is also reduced, the defects of the antibodies and tissues adhered to the antibodies and tissues are not overcome, and the small amount of the antibodies and tissues used in the experiment is definitely unacceptable.
Consequently, design a section can enough be effectively quick carry out even coating to immunohistochemical thing, and can effectively prevent immunohistochemical thing by the sticky tape to effectively promote the even ware is smeared to immunohistochemical antibody of the controllability of experiment by a wide margin the utility model discloses a research purpose.
Disclosure of Invention
To the problem that above-mentioned prior art exists, the utility model aims at providing an even ware is smeared to immunohistochemical antibody, the even ware is smeared to this immunohistochemical antibody can effectively solve the problem that above-mentioned prior art exists.
The technical scheme of the utility model is that:
an immunohistochemical antibody homogenizer, comprising:
a slide for placing an immunohistochemical substance;
the material distribution container is arranged on the upper surface of the glass slide, an opening of the material distribution container is arranged downwards, and the opening of the material distribution container is arranged in a plane shape;
the sealing washer is fixedly connected to the opening of the material distributing container;
a pressurizing mechanism for pressurizing an inner space of the material distribution container;
the pressure relief mechanism is used for relieving the pressure in the inner space of the cloth container;
and the pressing mechanism is used for pressing the cloth container.
The pressurizing mechanism comprises a pressurizing pipe integrally connected to the cloth container in a communicating mode, and the outer side of the pressurizing pipe is connected with a corresponding pressurizing air bag in a sealing mode.
The pressure relief mechanism comprises a pressure relief pipe integrally connected to the cloth container in a communicating mode, and a corresponding manual pressure relief valve is arranged on the pressure relief pipe in a fixing device.
The pressing mechanism comprises a pressing handle integrally and fixedly connected to the top of the cloth container, and one end, which is not fixedly connected to the cloth container, of the pressing handle is fixedly connected with a corresponding pressing plate.
The cloth container, the pressurizing pipe, the pressure relief pipe, the pressing handle and the pressing plate are all made of hard plastics.
The sealing washer is fixedly connected to the opening of the cloth container in an adhesive mode.
The opening of the pressurizing air bag is adhered to the pressurizing pipe and is tightened through a corresponding tightening rope.
The utility model has the advantages that:
1) the utility model discloses a cloth container sets up on the slide glass upper surface, and the opening of cloth container sets up downwards, and the opening part of cloth container sets to plane. In the coating process, firstly, the immune composition is dripped on a glass slide, and then a cloth container with a sealing washer is fastened at the periphery of the immune composition; the material distribution container is pressed tightly through a pressing mechanism, so that the sealing gasket at the opening of the material distribution container is tightly pressed on the glass slide in a sealing manner; then, the internal space of the material distribution container is effectively pressurized through a pressurizing mechanism, and the fluid immune composition is gradually pressed on the glass slide under the condition of positive pressure; and finally, the pressure relief mechanism is opened, so that the cloth container can be directly taken up after the inner space of the cloth container is effectively relieved. Thus, uniform coating of the immunohistochemical substance was completed. Can be used for effectively and rapidly uniformly coating the immunohistochemical substance and effectively preventing the immunohistochemical substance from being stuck, thereby effectively and greatly improving the controllability of the experiment.
2) The utility model discloses still have the advantage that the structure is simple and easy, low in manufacturing cost is honest and clean and long service life.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a state diagram in use during pressurization.
Fig. 3 is a diagram showing a state of use after completion of pressurization.
Detailed Description
To facilitate understanding of those skilled in the art, the structure of the present invention will now be described in further detail with reference to the following examples:
referring to fig. 1-3, an immunohistochemical antibody homogenizer comprising:
a slide 1 for placing an immunohistochemical substance;
the material distribution container 2 is arranged on the upper surface of the glass slide 1, the opening of the material distribution container 2 is arranged downwards, and the opening of the material distribution container 2 is arranged in a plane shape;
the sealing washer 3 is fixedly connected to the opening of the material distributing container 2;
a pressurizing mechanism 4 for pressurizing an inner space of the material container 2;
a pressure release mechanism 5 for releasing pressure in the internal space of the material container 2;
and the pressing mechanism 6 is used for pressing the cloth container 2.
The pressurizing mechanism 4 comprises a pressurizing pipe 401 integrally connected with the cloth container 2 in a communicating manner, and a corresponding pressurizing air bag 402 is hermetically connected to the outer side of the pressurizing pipe 401.
The pressure relief mechanism 5 comprises a pressure relief pipe 501 integrally connected to the cloth container 2 in a communicating manner, and a corresponding manual pressure relief valve 502 is arranged on the pressure relief pipe 501 in a fixing device.
The pressing mechanism 6 includes a pressing handle 601 integrally and fixedly connected to the top of the material container 2, and a corresponding pressing plate 602 is fixedly connected to one end of the pressing handle 601 not fixedly connected to the material container 2.
The cloth container 2, the pressurizing pipe 401, the pressure relief pipe 501, the pressing handle 601 and the pressing plate 602 are all made of hard plastic.
The sealing washer 3 is fixedly connected to the opening of the material container 2 in an adhesive manner.
The opening of the pressurizing airbag 402 is adhered to the pressurizing tube 401 and is fastened by a corresponding fastening string 7.
In the coating process, firstly, the immunohistochemical substance 8 is dripped on the glass slide 1, and then the cloth container 2 with the sealing washer 3 is fastened at the periphery of the immunohistochemical substance; the material distribution container 2 is pressed tightly through a pressing mechanism 6, so that the sealing gasket 3 at the opening is tightly pressed on the glass slide 1 in a sealing way; then, the internal space of the material distribution container 2 is effectively pressurized through a pressurizing mechanism 4, and the fluid immune composition 8 is gradually pressed on the glass slide 1 under the condition of positive pressure; and finally, the pressure relief mechanism 5 is opened, so that the cloth container 2 can be directly taken up after the internal space of the cloth container 2 is effectively relieved. Thus, uniform coating of the immunohistochemical substance was completed.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (7)
1. An immunohistochemical antibody homogenizer, comprising:
a slide (1) for placing an immunohistochemical substance;
the material distribution container (2) is arranged on the upper surface of the glass slide (1), an opening of the material distribution container (2) is arranged downwards, and the opening of the material distribution container (2) is arranged in a plane shape;
the sealing washer (3) is fixedly connected to the opening of the material distributing container (2);
a pressurizing mechanism (4) for pressurizing an inner space of the material distribution container (2);
a pressure release mechanism (5) for releasing the pressure in the inner space of the material distribution container (2);
and the pressing mechanism (6) is used for pressing the cloth container (2).
2. The immunohistochemical antibody homogenizer according to claim 1, wherein: the pressurizing mechanism (4) comprises a pressurizing pipe (401) integrally connected to the cloth container (2) in a communicating mode, and the outer side of the pressurizing pipe (401) is connected with a corresponding pressurizing air bag (402) in a sealing mode.
3. An immunohistochemical antibody homogenizer according to claim 2, wherein: the pressure relief mechanism (5) comprises a pressure relief pipe (501) integrally connected to the cloth container (2) in a communicating mode, and a corresponding manual pressure relief valve (502) is arranged on the pressure relief pipe (501) in a fixing device.
4. An immunohistochemical antibody homogenizer according to claim 3, wherein: the pressing mechanism (6) comprises a pressing handle (601) which is integrally and fixedly connected to the top of the cloth container (2), and one end of the pressing handle (601) which is not fixedly connected to the cloth container (2) is fixedly connected with a corresponding pressing plate (602).
5. An immunohistochemical antibody homogenizer according to claim 4, wherein: the cloth container (2), the pressurizing pipe (401), the pressure relief pipe (501), the pressing handle (601) and the pressing plate (602) are all made of hard plastics.
6. An immunohistochemical antibody homogenizer according to claim 5, wherein: the sealing washer (3) is fixedly connected to the opening of the cloth container (2) in an adhesive mode.
7. An immunohistochemical antibody homogenizer according to claim 2, wherein: the opening of the pressurizing air bag (402) is adhered to the pressurizing pipe (401) and is fastened through a corresponding fastening rope (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022597964.2U CN213600722U (en) | 2020-11-11 | 2020-11-11 | Immunohistochemical antibody smearing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022597964.2U CN213600722U (en) | 2020-11-11 | 2020-11-11 | Immunohistochemical antibody smearing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213600722U true CN213600722U (en) | 2021-07-02 |
Family
ID=76595432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022597964.2U Expired - Fee Related CN213600722U (en) | 2020-11-11 | 2020-11-11 | Immunohistochemical antibody smearing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213600722U (en) |
-
2020
- 2020-11-11 CN CN202022597964.2U patent/CN213600722U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210702 Termination date: 20211111 |