CN213516729U - External explosion pressure device - Google Patents

External explosion pressure device Download PDF

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Publication number
CN213516729U
CN213516729U CN202022451232.2U CN202022451232U CN213516729U CN 213516729 U CN213516729 U CN 213516729U CN 202022451232 U CN202022451232 U CN 202022451232U CN 213516729 U CN213516729 U CN 213516729U
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pipe
conduit
blood vessel
needle
pump
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CN202022451232.2U
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Chinese (zh)
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洪晓鸣
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Tianjin Haihe Mapping Technique Testing Co ltd
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Tianjin Haihe Mapping Technique Testing Co ltd
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Abstract

The utility model provides an external explosion pressure equipment device, including peristaltic pump, constant temperature water bath, blood vessel, first pipe clip, second pipe clip, connection needle, pipe, pressure sensor and syringe pump, be equipped with the stock solution device on the pipe, the pipe is connected gradually by first pipe, stock solution device and second pipe, and first pipe card is in the pump head of peristaltic pump, and in the constant temperature water bath was located to the stock solution device, the syringe needle and the second pipe connection of syringe pump, pressure sensor set up on the second pipe, and first pipe clip is located the pipe between peristaltic pump and the syringe pump, and second pipe clip is located the pipe between blood vessel and the pressure sensor. An external blasting pressure equipment device guaranteed in the experiment of external blasting pressure that the blood vessel carries out many times test and to the real-time supervision of closed end blasting pressure value at normal physiological state, can reach the part experimental animals of exemption simultaneously, accomplished the application of going to the market smoothly for supersound sword class product and laid the road.

Description

External explosion pressure device
Technical Field
The utility model belongs to the medical treatment field especially relates to an external explosion pressure equipment device.
Background
The examination and guidance principle of the registration technology of the ultrasonic soft tissue cutting hemostasis system indicates that the in vitro burst pressure experiment part needs at least 20 blood vessel burst pressure tests of each transducer and cutter head combination and a comparison product, and the aim mainly suggests that the blood vessel is tested in a normal physiological state during each test, so as to ensure the equivalence of the blood vessel and clinical application. On the basis of ensuring that the burst pressure test is completed under the normal physiological state, the simplest method capable of achieving the part of animal experiments is to take the blood vessel out, cut the test in vitro for multiple times and complete the burst pressure experiment by using in vitro burst pressure equipment.
Disclosure of Invention
In view of this, the utility model aims at providing an external blasting pressure equipment device has guaranteed that the blood vessel carries out a lot of tests and to the real-time supervision of closed end blasting pressure value in normal physiological state in the experiment is pressed in external blasting, can reach the part experimental animals of deduction simultaneously, has laid the road for supersound sword class product is accomplished the application of coming to the market smoothly.
An external explosion pressure device is characterized in that: including peristaltic pump, constant temperature water bath, blood vessel, first pipe clip, second pipe clip, connection needle, pipe, pressure sensor and syringe pump, be equipped with the stock solution device on the pipe, the pipe is connected gradually by first pipe, stock solution device and second pipe and is constituteed, and first pipe card is in the pump head of peristaltic pump, and in the constant temperature water bath was located to the stock solution device, be equipped with temperature sensor on the constant temperature water bath, the syringe needle and the second pipe connection of syringe pump, pressure sensor set up on the second pipe, and the second pipe clip is located the pipe between peristaltic pump and the syringe pump, and first pipe clip is located the pipe between blood vessel and the pressure sensor.
Further, the both sides of constant temperature water bath all are equipped with the recess, are equipped with two baffles on the recess, have on the baffle with recess complex pulley, make the pipe can not take place to remove in constant temperature water bath, can adjust the baffle according to the size of different pipes, make being heated of stock solution device more even.
Further, the diameter of the blood vessel is larger than 2 mm.
Further, the first conduit clamp and the second conduit clamp are both of a snap-fit type.
Further, the material of the conduit is PVC or PP.
Furthermore, the inside of connecting the needle is equipped with the internal thread, has on the pipe with internal thread complex external screw thread, connect needle and pipe for threaded connection, connect the needle for the needle of irritating the stomach. The connector of the intragastric perfusion needle is convenient to disassemble, and the blood vessels with different diameters can be connected according to different specifications, so that the requirement of testing is facilitated. And the head part of the stomach filling needle is in a round bulge shape, so that mechanical damage caused by external force action on the inner wall of the blood vessel is almost avoided, and after the stomach filling needle is connected with the blood vessel, the round bulge design of the head part can facilitate the fixation of the blood vessel and prevent the blood vessel from being separated.
Furthermore, the diameter of the needle tube of the connecting needle is 0.6-2.0 mm, and the length is 4-11 cm.
The physiological saline is injected into the connecting tube to the far end through the injection pump, and air is discharged. The two broken ends are connected with the blood vessel, the broken ends passing through the blood vessel are closed, the injection pump works, when the value of the pressure sensor is 18.7kpa, the injection pump is closed, the connecting pipe is loosened, the peristaltic pump is started, the value of the pressure sensor is ensured to be 18.7kpa, the normal physiological state of the blood vessel in the body is simulated, an ultrasonic knife product is used for detecting after the pressure is maintained, and then the burst pressure detection is carried out on the broken ends of the blood vessel.
Compared with the prior art, an external explosion pressure device has following advantage:
an external explosion pressure equipment device, the external explosion pressure equipment that can simulate human blood circulation links together syringe pump, peristaltic pump, pressure sensor, fully simulates the blood vessel in internal physiological state and can many times cut and measure the verification system of blood vessel closed end explosion pressure value. The successful research and development of the system solves the problems that the ultrasonic knife products can ensure that the blood vessels are tested for many times in a normal physiological state in an in-vitro explosion pressure experiment and the explosion pressure value of the closed end is monitored in real time, can achieve the purpose of reducing and exempting part of experimental animals, and paves a way for the ultrasonic knife products to successfully complete marketing application.
Drawings
The accompanying drawings, which form a part of the present disclosure, are provided to provide further understanding of the present disclosure, and the schematic test examples and the description thereof are used to explain the present disclosure and do not constitute an undue limitation on the present disclosure. In the drawings:
fig. 1 is an overall schematic view of an external burst pressure device according to the experimental example of the present invention;
fig. 2 is a schematic view of a guide pipe of an external burst pressure device according to an experimental example of the present invention;
fig. 3 is a schematic view of a constant temperature water bath of an external explosion pressure device according to the experimental example of the present invention.
Description of reference numerals:
1-a peristaltic pump; 2-a constant temperature water bath kettle; 3-blood vessels; 4-a first catheter clip; 5-a second catheter clip; 6-connecting a needle; 7-a catheter; 701-a first conduit; 702-a second conduit; 8-a pressure sensor; 9-a syringe pump; 10-a liquid storage device; 11-a temperature sensor; 12-a groove; 13-baffle.
Detailed Description
In addition, the features of the test examples and the test examples of the present invention may be combined with each other without conflict.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are used merely for convenience of description and for simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The present invention will be described in detail below with reference to the drawings and test examples.
As shown in fig. 1 to 3, an external burst pressure device is characterized in that: including peristaltic pump 1, constant temperature water bath 2, blood vessel 3, first pipe clip 4, second pipe clip 5, connecting needle 6, pipe 7, pressure sensor 8 and syringe pump 9, be equipped with stock solution device 10 on the pipe 7, pipe 7 is connected gradually by first pipe 701 stock solution device 10 and second pipe 702 and is constituteed, first pipe 701 card is in peristaltic pump 1's pump head, and stock solution device 10 is located in constant temperature water bath 2, is equipped with temperature sensor 11 on the constant temperature water bath 2, and the syringe needle and the second pipe 702 of syringe pump 9 are connected, and pressure sensor 8 sets up on second pipe 702, and second pipe clip 5 is located on pipe 7 between peristaltic pump 1 and the syringe pump 9, and first pipe clip 4 is located on pipe 7 between blood vessel 3 and the pressure sensor 8.
Both sides of constant temperature water bath 2 all are equipped with recess 12, are equipped with two baffles 13 on the recess 12, have on the baffle 13 with recess 12 complex pulley, make pipe 7 can not take place to remove in constant temperature water bath 2, can adjust baffle 13 according to the size of different pipes 7, make being heated of stock solution device 10 more even.
The diameter of the blood vessel 3 is larger than 2 mm.
The first catheter clamp 4 and the second catheter clamp 5 are both snap-fit.
The material of the conduit 7 is PVC or PP.
The inside of connecting needle 6 is equipped with the internal thread, has on the pipe 7 with internal thread complex external screw thread, connect needle 6 and pipe 7 for threaded connection, connect needle 6 for the needle of irritating the stomach. The connector of the intragastric perfusion needle is convenient to detach, and the blood vessels 3 with different diameters can be connected according to different specifications, so that the requirement of testing is facilitated. And the head part of the stomach filling needle is in a round bulge shape, so that mechanical damage caused by external force action to the inner wall of the blood vessel 3 is almost avoided, and after the stomach filling needle is connected with the blood vessel 3, the round bulge design of the head part can facilitate the fixation of the blood vessel 3 and prevent the blood vessel 3 from being separated.
The diameter of the needle tube of the connecting needle 6 is 0.6-2.0 mm, and the length is 4-11 cm.
Test example 1
(1) The injector pumps warm saline, fills the saline into the pipeline, and exhausts the air in the pipeline.
(2) And opening the constant-temperature water bath kettle 2, setting the temperature to be the normal body temperature of the animal, and finishing the assembly of the device.
(3) The isolated blood vessel 3 is taken out, and two broken ends of the pipeline are connected with the blood vessel 3.
(4) The first catheter clamp 4 is opened, the second catheter clamp 5 is closed, the injection pump 9 is opened, warm physiological saline in the first catheter clamp is slowly injected into the pipeline, and when the value of the pressure sensor 8 is 18.7kpa, the injection pump 9 is closed. The value of the pressure sensor 8 is controlled by the peristaltic pump 1, and the flow rate of the peristaltic pump 1 can be adjusted to 9-10 intervals, wherein the unit is L/min. The value of the pressure sensor 8 can be controlled within the normal blood pressure range, namely within the range of 12-18.7 kpa.
(5) The second catheter clamp 5 is opened and the peristaltic pump 1 is then started, ensuring that the value of the pressure sensor 8 is stabilized at 18.7 kpa.
(6) The blood vessel 3 is cut using an ultrasonic blade. And selecting an artery with the blood vessel diameter of 3.42 mm for testing.
(7) And after the cutting is finished, closing the peristaltic pump 1 and the second catheter clamp 5, opening the injection pump 9, slowly injecting the physiological saline, and slowly injecting the physiological saline in the injection pump 9 at the flow rate of 20-25ml/min to obtain the burst pressure value of one end of the blood vessel 3.
(8) Only one end of the device needs to be measured to burst pressure, and the other broken end is cut off by operation.
The test results showed a closed end pressure value of 110.2 kpa.
Test example 2
Different from experimental example 1, the test was carried out on a vein having a blood vessel diameter of 3.50 mm, and the test result showed that the closing end pressure value was 94.3 kpa.
Test example 3
The test was carried out on an artery having a blood vessel diameter of 5.68 mm, which was different from that of experimental example 1, and the test result showed that the closing end pressure value was 83.2 kpa.
Test example 4
Different from experimental example 1, the test was carried out on a vein having a blood vessel diameter of 7.14 mm, and the test result showed that the closing end pressure value was greater than 54.2 kpa.
The above description is only a preferred example of the present invention, and should not be construed as limiting the present invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (7)

1. An external explosion pressure device is characterized in that: comprises a peristaltic pump (1), a constant temperature water bath (2), a blood vessel (3), a first conduit clamp (4), a second conduit clamp (5), a connecting needle (6), a conduit (7), a pressure sensor (8) and an injection pump (9), wherein the conduit (7) is provided with a liquid storage device (10), the conduit (7) is formed by sequentially connecting a first conduit (701), the liquid storage device (10) and a second conduit (702), the first conduit (701) is clamped in the pump head of the peristaltic pump (1), the liquid storage device (10) is arranged in the constant temperature water bath (2), the constant temperature water bath (2) is provided with a temperature sensor (11), the injection needle of the injection pump (9) is connected with the second conduit (702), the pressure sensor (8) is arranged on the second conduit (702), the second conduit clamp (5) is positioned on the conduit (7) between the peristaltic pump (1) and the injection pump (9), the first catheter clip (4) is located on the catheter (7) between the blood vessel (3) and the pressure sensor (8).
2. An apparatus according to claim 1, characterized in that: both sides of the constant temperature water bath (2) are provided with grooves (12), the grooves (12) are provided with two baffle plates (13), and the baffle plates (13) are provided with pulleys matched with the grooves (12).
3. An apparatus according to claim 1, characterized in that: the diameter of the blood vessel (3) is larger than 2 mm.
4. An apparatus according to claim 1, characterized in that: the first catheter clamp (4) and the second catheter clamp (5) are both in a buckling mode.
5. An apparatus according to claim 1, characterized in that: the material of the conduit (7) is PVC or PP.
6. An apparatus according to claim 1, characterized in that: the inside of connecting needle (6) is equipped with the internal thread, has on pipe (7) with internal thread complex external screw thread, connect needle (6) and pipe (7) for threaded connection, connect needle (6) for the needle of irritating the stomach.
7. An apparatus according to claim 1, characterized in that: the diameter of the needle tube of the connecting needle (6) is 0.6-2.0 mm, and the length is 4-11 cm.
CN202022451232.2U 2020-10-29 2020-10-29 External explosion pressure device Active CN213516729U (en)

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Application Number Priority Date Filing Date Title
CN202022451232.2U CN213516729U (en) 2020-10-29 2020-10-29 External explosion pressure device

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114260032A (en) * 2021-12-01 2022-04-01 中国科学院大学深圳医院(光明) Micro-fluidic chip platform for establishing in-vitro vascular physiology model
CN115266388A (en) * 2022-09-28 2022-11-01 江苏科标医学检测有限公司 Vascular explosion tester and working method thereof
CN115672431A (en) * 2022-10-18 2023-02-03 哈尔滨工业大学(威海) Extracorporeal circulation and intraluminal intervention isolated blood vessel constant temperature auxiliary device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114260032A (en) * 2021-12-01 2022-04-01 中国科学院大学深圳医院(光明) Micro-fluidic chip platform for establishing in-vitro vascular physiology model
CN115266388A (en) * 2022-09-28 2022-11-01 江苏科标医学检测有限公司 Vascular explosion tester and working method thereof
CN115672431A (en) * 2022-10-18 2023-02-03 哈尔滨工业大学(威海) Extracorporeal circulation and intraluminal intervention isolated blood vessel constant temperature auxiliary device

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