CN213468465U

CN213468465U - Automatic greasing device for sealing protein crystallization plate

Info

Publication number: CN213468465U
Application number: CN202022267971.6U
Authority: CN
Inventors: 张波
Original assignee: Taiyuan University of Science and Technology
Current assignee: Taiyuan University of Science and Technology
Priority date: 2020-10-13
Filing date: 2020-10-13
Publication date: 2021-06-18
Anticipated expiration: 2030-10-13

Abstract

The utility model relates to a bioengineering technical field especially is used for sealed automatic fat liquoring device of protein crystallization board, comprising a base plate, one side fixedly connected with fixing base on bottom plate surface top, the inside sliding connection of fixing base has the stand, the inside sliding connection of stand has the crossbeam, the inside sliding connection of crossbeam has the mounting bracket. The utility model has the advantages that: through the one side fixed connection fixing base at the bottom plate top surface, there is the stand in the inside sliding connection of fixing base, there is the crossbeam in the inside sliding connection of stand, the sliding connection of crossbeam has the mounting bracket, wherein the stand, crossbeam and mounting bracket are respectively through first motor, second motor and third motor drive carry out the transmission, a packing element has clamped in the inside of mounting bracket, top surface fixedly connected with cylinder at the mounting bracket, the output of cylinder and the pressing end fixed connection of packing element, it can carry out the three-dimensional space motion to reach the packing element, it seals the purpose to have realized the machine, and convenient to use.

Description

Automatic greasing device for sealing protein crystallization plate

Technical Field

The utility model relates to the technical field of biological engineering, in particular to an automatic greasing device for sealing a protein crystallization plate.

Background

The protein is the main undertaker of life activity, the understanding of the three-dimensional structure is the premise of understanding the protein function, the current commonly used protein crystallization methods include a hanging drop gas phase diffusion method, a sitting drop gas phase diffusion method, an oil coating method and the like, the hanging drop gas phase diffusion method is to drop the protein solution to be crystallized, the crystal screening solution and the like on a glass sheet, a plastic sheet or a special adhesive tape coated with a sealing material and to reversely buckle the glass sheet, the plastic sheet or the special adhesive tape on the pool liquid containing the crystal screening solution. The sitting drop gas phase diffusion method requires that the mixed solution of the protein solution to be crystallized and the crystallization screening solution is dropped into a dropping tank and sealed by a special plastic film or an adhesive tape.

The current method for sealing the twenty-four well crystallization plate is manual greasing. The sealing effect of the twenty-four hole crystallization plate can be influenced by the manual operation proficiency and the vacuum sealing grease smearing feeling, and the twenty-four hole crystallization plate with poor sealing effect can not be used for protein crystallization, so that the twenty-four hole crystallization plate is scrapped, and the cost is influenced.

SUMMERY OF THE UTILITY MODEL

The utility model aims to overcome the defects of the prior art, provides an automatic greasing device for sealing a protein crystallization plate, and effectively solves the defects of the prior art.

The purpose of the utility model is realized through the following technical scheme: an automatic greasing device for sealing a protein crystallization plate, comprising a bottom plate;

the rubber tube fixing device is characterized in that a fixing seat is fixedly connected to one side of the top end of the outer surface of the bottom plate, an upright column is slidably connected to the inside of the fixing seat, a cross beam is slidably connected to the inside of the upright column, a mounting frame is slidably connected to the inside of the cross beam, the upright column, the cross beam and the mounting frame are driven by a first motor, a second motor and a third motor respectively to perform transmission, the first motor is fixedly connected to one side of the outer surface of the fixing seat, the second motor is fixedly connected to the top end of the outer surface of the upright column, the third motor is fixedly connected to one end of the outer surface of the cross beam, a clamping hole is formed in the bottom end of the inside of the mounting frame, a rubber tube is clamped inside the;

the bottom plate surface top all seted up a plurality of mounting holes in the four corners department, it is a plurality of the position of mounting hole is symmetrical about the central line of bottom plate, the top surface of bottom plate is provided with four hornblocks, four the equal fixedly connected with card post in middle part of hornblock surface bottom, four card post respectively with mounting hole looks joint, four be provided with the crystallization plate body between the hornblock.

Optionally, the first motor, the second motor and the third motor are respectively and fixedly connected with the fixing base, the upright post and the cross beam through bolts, and the output ends of the first motor, the second motor and the third motor are respectively provided with a lead screw.

Optionally, the inner diameter of the clamping hole is equal to the diameter of the rubber cylinder, and the bottom surface of the top end of the rubber cylinder is attached to the bottom surface of the inner wall of the mounting frame.

Optionally, the inner diameter of the mounting hole is slightly smaller than the diameter of the clamping column, and the depth of the inner wall of the mounting hole is slightly larger than the height of the clamping column.

Optionally, the four corner blocks are all L-shaped, and the inner sides of the outer surfaces of the four corner blocks are mutually spliced to form a square.

Optionally, the output end of the air cylinder is fixedly connected with the pressing end of the rubber sleeve through a bolt, the output end of the air cylinder penetrates through the mounting frame, and the air cylinder is fixedly connected with the mounting frame through a bolt.

The utility model has the advantages of it is following:

1. this an automatic fat liquoring device for protein crystallization plate is sealed, through one side fixed connection fixing base at the bottom plate top surface, there is the stand at the inside sliding connection of fixing base, there is the crossbeam at the inside sliding connection of stand, the sliding connection of crossbeam has the mounting bracket, wherein the stand, crossbeam and mounting bracket are respectively through first motor, second motor and third motor drive carry out the transmission, and seted up the card hole in the inside bottom of mounting bracket, the inside in card hole clamps the packing element, simultaneously at the top surface fixedly connected with cylinder of mounting bracket, the output of cylinder and the pressing end fixed connection of packing element, and then reach the packing element and can carry out the three-dimensional space motion, realized that the machine carries out the purpose sealed, and is rational in infrastructure, and convenient to use.

2. This an automatic fat liquoring device for protein crystallization plate is sealed, set up a plurality of mounting holes through the four corners department at the bottom plate top surface, the position of a plurality of mounting holes is corresponding, simultaneously, the hornblock has been clamped in the inside of mounting hole, four hornblock cooperations are used, make the crystallization plate body of a plurality of sizes that whole device can fix, to a certain extent, increased the practicality of whole device, the person of facilitating the use uses, simultaneously, whole device simple structure, the operating personnel of being convenient for carries out the later maintenance to it.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic structural view of the bottom plate of the present invention;

fig. 3 is a schematic structural view of the mounting frame of the present invention;

fig. 4 is a schematic structural diagram of the corner block of the present invention.

In the figure: 1-bottom plate, 2-crystallization plate body, 3-first motor, 4-fixed seat, 5-rubber cylinder, 6-upright post, 7-second motor, 8-cylinder, 9-cross beam, 10-mounting rack, 11-third motor, 12-corner block, 13-clamping column, 14-mounting hole and 15-clamping hole.

Detailed Description

The invention will be further described with reference to the accompanying drawings, but the scope of the invention is not limited to the following description.

As shown in fig. 1 to 4, an automatic greasing device for sealing a protein crystallization plate includes a base plate 1;

one side of the top end of the outer surface of the bottom plate 1 is fixedly connected with a fixed seat 4, the inside of the fixed seat 4 is slidably connected with a stand column 6, the inside of the stand column 6 is slidably connected with a cross beam 9, the inside of the cross beam 9 is slidably connected with an installation frame 10, the stand column 6, the cross beam 9 and the installation frame 10 are respectively driven by a first motor 3, a second motor 7 and a third motor 11 to carry out transmission, the first motor 3 is fixedly connected to one side of the outer surface of the fixed seat 4, the second motor is fixedly connected to the top end of the outer surface of the stand column 6, the third motor 11 is fixedly connected to one end of the outer surface of the cross beam 9, a clamping hole 15 is formed in the bottom end of the inside of the installation frame 10, a rubber cylinder 5 is clamped in the clamping;

a plurality of mounting holes 14 have all been seted up to the four corners department on bottom plate 1 surface top, and the central line symmetry about bottom plate 1 in the position of a plurality of mounting holes 14, and bottom plate 1's top surface is provided with four corner blocks 12, the equal fixedly connected with card post 13 in middle part of four corner blocks 12 surface bottoms, and four card posts 13 are connected with mounting hole 14 looks joint respectively, are provided with crystallization plate body 2 between four corner blocks 12.

As the utility model discloses an optional technical scheme:

first motor 3, second motor 7 and third motor 11 all through the bolt respectively with fixing base 4, stand 6 and crossbeam 9 fixed connection, first motor 3, the output of second motor 7 and third motor 11 all is provided with the lead screw, be threaded connection between lead screw and stand 6, crossbeam 9 and the mounting bracket 10, and then realized stand 6, crossbeam 9 and mounting bracket 10's motion, make whole device accord with mechanical design's principle and the custom of in-service use.

As the utility model discloses an optional technical scheme:

the internal diameter of card hole 15 equals with the diameter of packing element 5, and the bottom surface on packing element 5 top is laminated with the bottom surface of mounting bracket 10 inner wall mutually, clamps packing element 5 in the inside of card hole 15, guarantees its rigidity, avoids appearing removing in the use, and convenient to use person installs simultaneously and dismantles the change.

As the utility model discloses an optional technical scheme:

the inner diameters of the mounting holes 14 are slightly smaller than the diameter of the clamping column 13, the depths of the inner walls of the mounting holes 14 are slightly larger than the height of the clamping column 13, clamping of the clamping column 13 and the mounting holes 14 is achieved, the position of the corner block 12 is guaranteed to be firm, and looseness of the corner block in the using process is prevented.

As the utility model discloses an optional technical scheme:

four corner pieces 12 are the L type, and the inboard of four corner pieces 12 surfaces is each other amalgamation squarely, and four corner pieces 12 cooperation are used, make whole device can fix the crystallization plate body 2 of a plurality of sizes, to a certain extent, have increased the practicality of whole device, and the person of facilitating the use uses.

As an optional technical proposal of the utility model

Through bolt fixed connection between the output of cylinder 8 and the pressing end of packing element 5, the output of cylinder 8 runs through mounting bracket 10, and cylinder 8 passes through bolt and mounting bracket 10 fixed connection, makes cylinder 8 can drive packing element 5 and carry out crowded gluey operation, and through the two of bolted connection, can reach convenient to use person and dismantle and change packing element 5.

The working process of the utility model is as follows: when a user uses the sealing device, the fixed seat 4 is fixedly connected to one side of the top surface of the bottom plate 1, the upright 6 is slidably connected to the inside of the fixed seat 4, the cross beam 9 is slidably connected to the inside of the upright 6, the mounting frame 10 is slidably connected to the cross beam 9, the upright 6, the cross beam 9 and the mounting frame 10 are driven by the first motor 3, the second motor 7 and the third motor 11 respectively to transmit, the bottom end of the inside of the mounting frame 10 is provided with a clamping hole 15, the rubber cylinder 5 is clamped in the clamping hole 15, the top surface of the mounting frame is fixedly connected with the cylinder 8, the output end of the cylinder 8 is fixedly connected with the pressing end of the rubber cylinder 5, and therefore the rubber cylinder 5 can move in a three-dimensional space manner, the purpose of sealing of the machine is achieved, the sealing device is reasonable in structure and convenient to use, the positions of the mounting holes 14 are corresponding to, simultaneously, the inside at mounting hole 14 clamps has the hornblock 12, and four hornblocks 12 cooperate the use, make whole device can fix the crystallization plate body 2 of a plurality of sizes, to a certain extent, have increased the practicality of whole device, and the person of facilitating the use uses, and simultaneously, whole device simple structure, the operating personnel of being convenient for carries out the later maintenance to it.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. An automatic greasing device for sealing a protein crystallization plate, which is characterized in that: comprises a bottom plate (1);

the bottom plate is characterized in that a fixing seat (4) is fixedly connected to one side of the top end of the outer surface of the bottom plate (1), a stand column (6) is connected to the inner portion of the fixing seat (4) in a sliding mode, a cross beam (9) is connected to the inner portion of the stand column (6) in a sliding mode, a mounting frame (10) is connected to the inner portion of the cross beam (9) in a sliding mode, the stand column (6), the cross beam (9) and the mounting frame (10) are driven to transmit through a first motor (3), a second motor (7) and a third motor (11) respectively, the first motor (3) is fixedly connected to one side of the outer surface of the fixing seat (4), the second motor is fixedly connected to the top end of the outer surface of the stand column (6), the third motor (11) is fixedly connected to one end of the outer surface of the cross beam (9), a clamping hole, the top end of the outer surface of the mounting frame (10) is fixedly connected with an air cylinder (8), and the output end of the air cylinder (8) is fixedly connected with the pressing end of the rubber cylinder (5);

a plurality of mounting holes (14) have all been seted up, a plurality of to the four corners department on bottom plate (1) surface top the position of mounting hole (14) is about the central line symmetry of bottom plate (1), the top surface of bottom plate (1) is provided with four corner blocks (12), four the equal fixedly connected with in middle part of corner block (12) surface bottom blocks post (13), four block post (13) respectively with mounting hole (14) looks joint, four be provided with crystallization plate body (2) between corner block (12).

2. The automated fat liquoring device for protein crystallization plate sealing as claimed in claim 1, wherein: first motor (3), second motor (7) and third motor (11) all through bolt respectively with fixing base (4), stand (6) and crossbeam (9) fixed connection, the output of first motor (3), second motor (7) and third motor (11) all is provided with the lead screw.

3. The automated fat liquoring device for protein crystallization plate sealing as claimed in claim 1, wherein: the internal diameter of card hole (15) equals with the diameter of packing element (5), the bottom surface on packing element (5) top is laminated with the bottom surface of mounting bracket (10) inner wall mutually.

4. The automated fat liquoring device for protein crystallization plate sealing as claimed in claim 1, wherein: the inner diameters of the mounting holes (14) are slightly smaller than the diameter of the clamping column (13), and the depths of the inner walls of the mounting holes (14) are slightly larger than the height of the clamping column (13).

5. The automated fat liquoring device for protein crystallization plate sealing as claimed in claim 1, wherein: the four corner blocks (12) are L-shaped, and the inner sides of the outer surfaces of the four corner blocks (12) are mutually spliced to form a square.

6. The automated fat liquoring device for protein crystallization plate sealing as claimed in claim 1, wherein: the output end of the air cylinder (8) is fixedly connected with the pressing end of the rubber cylinder (5) through a bolt, the output end of the air cylinder (8) penetrates through the mounting frame (10), and the air cylinder (8) is fixedly connected with the mounting frame (10) through a bolt.