CN213434390U - Novel reaction device for anidulafungin key process - Google Patents
Novel reaction device for anidulafungin key process Download PDFInfo
- Publication number
- CN213434390U CN213434390U CN201922371079.XU CN201922371079U CN213434390U CN 213434390 U CN213434390 U CN 213434390U CN 201922371079 U CN201922371079 U CN 201922371079U CN 213434390 U CN213434390 U CN 213434390U
- Authority
- CN
- China
- Prior art keywords
- stirring rod
- kettle body
- rotating shaft
- rod
- anidulafungin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Physical Or Chemical Processes And Apparatus (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
Abstract
The invention provides a novel reaction device for an anidulafungin key process, which comprises a reaction kettle body, wherein a rotating shaft is arranged in the middle of the reaction kettle body, a support is arranged on the top surface of the reaction kettle body, a lifting cylinder is arranged on the top surface of the support, a transmission rod is connected to the lower end of a piston rod of the lifting cylinder, two magnet rings arranged up and down are sleeved on the transmission rod, a motor is further arranged on the support, a positioning ring, an upper sliding ring and a lower sliding ring are sequentially sleeved on the rotating shaft in the reaction kettle body from top to bottom, the outer side of the positioning ring is rotatably connected with a first upper stirring rod and a second upper stirring rod, the lower end of the first upper stirring rod is rotatably connected with a first lower stirring rod, and the lower end of the. The advantages are that: through the strong magnetic force between the magnet ring and the magnetic metal sliding ring, when the lifting cylinder drives the transmission rod to reciprocate up and down, the first upper stirring rod and the first lower stirring rod are repeatedly opened and closed, and the second upper stirring rod and the second lower stirring rod are repeatedly opened and closed, so that the reaction efficiency is improved.
Description
Technical Field
The invention relates to the technical field of anidulafungin, in particular to a novel reaction device for a key process of anidulafungin.
Background
Anidulafungin has shown efficacy against various candidiasis with in vivo and in vitro activities, and studies published at the 2005 ICAAC conference have shown that: compared with fluconazole, anidulafungin is used for treating candidemia and invasive candidiasis, and in the key process of anidulafungin, a reaction kettle is indispensable equipment, and at present, the reaction rate of materials in the existing reaction kettle is low, so that the production efficiency and the quality of finished products are influenced.
Disclosure of Invention
In order to solve the problems, the invention discloses a novel reaction device for an anidulafungin key process, which effectively improves the disorder degree of materials and improves the reaction efficiency.
In order to achieve the above purpose, the invention provides the following technical scheme:
a novel reaction unit of anidulafungin key technology, its characterized in that: the automatic feeding device comprises a reaction kettle body, wherein a vertically arranged rotating shaft is arranged in the middle of the reaction kettle body, the rotating shaft is of a hollow cylindrical structure, the upper end of the rotating shaft penetrates through the upper middle part of the reaction kettle body and is connected with the upper middle part of the reaction kettle body in a rotating mode through a bearing, a support is arranged in the middle of the top surface of the reaction kettle body, a lifting cylinder is arranged in the middle of the top surface of the support, a piston rod of the lifting cylinder is arranged downwards, the lower end of the piston rod is connected with a transmission rod which is vertically arranged, the lower end of the transmission rod penetrates through the upper middle part of the rotating shaft and is arranged in an inner cavity of the rotating shaft, two magnet rings which are arranged up and down are sleeved on the lower section of the transmission rod, a driven gear is sleeved outside the upper end of the rotating shaft, a motor is further arranged on the support, the upper end of the first lower stirring rod is rotationally connected with the lower end of the first upper stirring rod, the lower end of the first lower stirring rod is rotationally connected with a second lower stirring rod, the upper end of the second upper stirring rod is rotationally connected with the positioning ring, the lower end of the second lower stirring rod is rotationally connected with a second lower stirring rod, the upper end of the second lower stirring rod is rotationally connected with the lower end of the second upper stirring rod, the lower end of the second lower stirring rod is rotationally connected with the lower end of the lower stirring rod, the lower end of the second lower stirring rod is rotationally connected with the lower sliding ring, and the first upper stirring rod is smaller than the second upper stirring rod, the upper sliding ring and the lower sliding ring are both magnetic metal sliding rings.
Furthermore, the first upper stirring rod is the same as the first lower stirring rod, and the second upper stirring rod is the same as the second lower stirring rod.
Furthermore, the rotating shaft is a non-magnetic rotating shaft.
Furthermore, the lower extreme of pivot is equipped with anchor formula stirring rake.
Further, a feed inlet and a discharge outlet are respectively arranged at the upper end and the lower end of the reaction kettle body.
Furthermore, the lower extreme overcoat of the reation kettle body is equipped with the support shell, the bottom of supporting the shell is equipped with the support.
Compared with the prior art, the invention has the beneficial effects that: through the strong magnetic force between the magnet rings and the magnetic metal sliding rings, when the lifting cylinder drives the transmission rod to reciprocate up and down, the upper magnet ring and the lower magnet ring synchronously drive the upper sliding ring and the lower sliding ring to reciprocate up and down, so that the first upper stirring rod and the first lower stirring rod are repeatedly opened and closed, the second upper stirring rod and the second lower stirring rod are repeatedly opened and closed, meanwhile, the rotating shaft drives the stirring rods to do circular motion under the driving of the motor, and therefore the degree of disorder of materials is greatly improved, and the reaction efficiency is improved.
Drawings
FIG. 1 is a schematic structural diagram of a novel reaction device for an anidulafungin key process of the present invention.
FIG. 2 is a top view of a positioning ring in a novel reaction apparatus for a key process of anidulafungin according to the present invention.
FIG. 3 is a top view of the upper slip ring of the novel reaction apparatus for the key process of anidulafungin according to the present invention.
FIG. 4 is a top view of a lower slip ring in a novel reaction apparatus for an anidulafungin key process of the present invention.
List of reference numerals:
1-a reaction kettle body, 2-a rotating shaft, 3-a bearing, 4-a bracket, 5-a lifting cylinder, 6-a transmission rod, 7-a magnet ring, 8-a driven gear, 9-a motor, 10-a driving gear, 11-a positioning ring, 12-an upper sliding ring, 13-a lower sliding ring, 14-a first upper stirring rod, 15-a second upper stirring rod, 16-a first lower stirring rod, 17-a second lower stirring rod, 18-an anchor type stirring paddle, 19-a feeding port, 20-a discharging port, 21-a supporting shell and 22-a support.
Detailed Description
The present invention will be further illustrated with reference to the accompanying drawings and specific embodiments, which are to be understood as merely illustrative of the invention and not as limiting the scope of the invention. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.
As shown in the figure, the novel reaction device for the key process of anidulafungin comprises a reaction kettle body 1, wherein a vertically arranged rotating shaft 2 is arranged in the middle of the reaction kettle body 1, the rotating shaft 2 is of a hollow cylindrical structure, the upper end of the rotating shaft 2 penetrates through the middle of the upper end of the reaction kettle body 1 and is rotatably connected with the middle of the upper end of the reaction kettle body 1 through a bearing 3, a support 4 is arranged in the middle of the top surface of the reaction kettle body 1, a lifting cylinder 5 is arranged in the middle of the top surface of the support 4, a piston rod of the lifting cylinder 5 is downwards arranged, the lower end of the piston rod is connected with a vertically arranged transmission rod 6, the lower end of the transmission rod 6 penetrates through the middle of the upper end of the rotating shaft 3 and is placed in an inner cavity of the rotating shaft 3, two vertically arranged magnet rings 7 are sleeved on the lower section of the transmission rod, the driving gear 10 is engaged with the driven gear 8, a positioning ring 11, an upper sliding ring 12 and a lower sliding ring 13 are sequentially sleeved on a rotating shaft in the reaction kettle body 1 from top to bottom, the positioning ring 11, the upper sliding ring 12 and the lower sliding ring 13 are of the same annular structure, the positioning ring 11 is fixedly sleeved outside the rotating shaft 2, the upper sliding ring 12 and the lower sliding ring 13 can be sleeved on the rotating shaft 2 in a vertically sliding manner, a first upper stirring rod 14 and a second upper stirring rod 15 are rotatably connected to the outer side of the positioning ring 11 in the circumferential direction, the upper end of the first upper stirring rod 14 is rotatably connected with the positioning ring 11, the lower end of the first upper stirring rod 14 is rotatably connected with a first lower stirring rod 16, the upper end of the first lower stirring rod 16 is rotatably connected with the lower end of the first upper stirring rod 14, the lower end of the first upper stirring rod is rotatably connected with the upper sliding ring 12, the upper end of the second, the upper end of the second lower stirring rod 17 is rotatably connected with the lower end of the second upper stirring rod 15, the lower end is rotatably connected with the lower sliding ring 13, the first upper stirring rod 14 is smaller than the second upper stirring rod 15, and the upper sliding ring 12 and the lower sliding ring 13 are both magnetic metal sliding rings.
In the present embodiment, the first upper stirring rod 14 and the first lower stirring rod 16 are the same, and the second upper stirring rod 15 and the second lower stirring rod 17 are the same.
In the present embodiment, the shaft 2 is a nonmagnetic shaft.
In this embodiment, the lower end of the rotating shaft 2 is provided with an anchor type stirring paddle 18.
In this embodiment, the upper end and the lower end of the reaction vessel body 1 are respectively provided with a feed inlet 19 and a discharge outlet 20.
In this embodiment, a support shell 21 is sleeved outside the lower end of the reaction vessel body 1, and a support 22 is provided at the bottom of the support shell 21.
According to the invention, through the strong magnetic force between the magnet rings 7 and the magnetic metal sliding rings, when the lifting cylinder 5 drives the transmission rod 6 to reciprocate up and down, the upper magnet ring 7 and the lower magnet ring 7 synchronously drive the upper sliding ring 12 and the lower sliding ring 13 to reciprocate up and down, so that the first upper stirring rod 14 and the first lower stirring rod 16 are repeatedly opened and closed, the second upper stirring rod 15 and the second lower stirring rod 17 are repeatedly opened and closed, and meanwhile, the rotating shaft 2 drives the stirring rods to do circular motion under the driving of the motor 9, thereby greatly improving the degree of disorder of materials and improving the reaction efficiency.
The technical means disclosed in the invention scheme are not limited to the technical means disclosed in the above embodiments, but also include the technical scheme formed by any combination of the above technical features. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principle of the present invention, and such improvements and modifications are also considered to be within the scope of the present invention.
Claims (6)
1. A novel reaction unit of anidulafungin key technology, its characterized in that: comprises a reaction kettle body (1), wherein a vertically arranged rotating shaft (2) is arranged in the middle of the reaction kettle body (1), the rotating shaft (2) is of a hollow cylindrical structure, the upper end of the rotating shaft (2) penetrates through the upper middle part of the reaction kettle body (1) and is rotatably connected with the upper middle part of the reaction kettle body (1) through a bearing (3), a support (4) is arranged in the middle of the top surface of the reaction kettle body (1), a lifting cylinder (5) is arranged in the middle of the top surface of the support (4), a piston rod of the lifting cylinder (5) is arranged downwards, the lower end of the piston rod is connected with a vertically arranged transmission rod (6), the lower end of the transmission rod (6) penetrates through the middle of the upper end of the rotating shaft (2) and is arranged in an inner cavity of the rotating shaft (2), two magnet rings (7) which are arranged up and down are sleeved on the lower section of the transmission rod (6, still be equipped with motor (9) on support (4), the motor shaft tip of motor (9) is equipped with driving gear (10), driving gear (10) meshes with driven gear (8) mutually, top-down overlaps in proper order on pivot (2) in the reation kettle body (1) and is equipped with holding ring (11), last sliding ring (12) and lower sliding ring (13), holding ring (11), last sliding ring (12) and lower sliding ring (13) are the same ring structure, and the fixed cover of holding ring (11) is established outside pivot (2), and the cover that can slide from top to bottom of last sliding ring (12) and lower sliding ring (13) is established on pivot (2), swing joint has upper stirring rod (14) and upper stirring rod (15) of second in the outside circumference direction of holding ring (11), the upper end and the holding ring (11) of upper stirring rod (14) rotate and be connected, the lower extreme rotates and is connected with first stirring rod (16) down, the upper end of first stirring rod (16) rotates with the lower extreme of first upper stirring rod (14) to be connected, and the lower extreme rotates with last throw-out collar (12) to be connected, the upper end of stirring rod (15) rotates with holding ring (11) on the second to be connected, and the lower extreme rotates and is connected with second lower stirring rod (17), the upper end of stirring rod (17) rotates with the lower extreme of second upper stirring rod (15) to be connected under the second, and the lower extreme rotates with lower throw-out collar (13) to be connected, first upper stirring rod (14) is less than second upper stirring rod (15), go up throw-out collar (12) and lower throw-out collar (13) and be magnetic metal slip ring.
2. The novel reaction device for anidulafungin key process according to claim 1, characterized in that: the first upper stirring rod (14) is the same as the first lower stirring rod (16), and the second upper stirring rod (15) is the same as the second lower stirring rod (17).
3. The novel reaction device for anidulafungin key process according to claim 1, characterized in that: the rotating shaft (2) is a non-magnetic rotating shaft.
4. The novel reaction device for anidulafungin key process according to claim 1, characterized in that: the lower end of the rotating shaft (2) is provided with an anchor type stirring paddle (18).
5. The novel reaction device for anidulafungin key process according to claim 1, characterized in that: the upper end and the lower end of the reaction kettle body (1) are respectively provided with a feeding hole (19) and a discharging hole (20).
6. The novel reaction device for anidulafungin key process according to claim 1, characterized in that: the lower extreme overcoat of the reation kettle body (1) is equipped with and supports shell (21), the bottom that supports shell (21) is equipped with support (22).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922371079.XU CN213434390U (en) | 2019-12-25 | 2019-12-25 | Novel reaction device for anidulafungin key process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922371079.XU CN213434390U (en) | 2019-12-25 | 2019-12-25 | Novel reaction device for anidulafungin key process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213434390U true CN213434390U (en) | 2021-06-15 |
Family
ID=76286225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922371079.XU Active CN213434390U (en) | 2019-12-25 | 2019-12-25 | Novel reaction device for anidulafungin key process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213434390U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114307775A (en) * | 2021-12-08 | 2022-04-12 | 安徽华塑股份有限公司 | Polyvinyl chloride alloy preparation facilities |
| CN114522778A (en) * | 2022-03-03 | 2022-05-24 | 黄河水利职业技术学院 | Civil engineering waste environment-friendly treatment device with anti-blocking system and treatment method thereof |
| CN116328686A (en) * | 2023-02-21 | 2023-06-27 | 江苏德鑫新材料科技有限公司 | Reaction kettle for preparing nano spherical silicon dioxide dispersion liquid |
-
2019
- 2019-12-25 CN CN201922371079.XU patent/CN213434390U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114307775A (en) * | 2021-12-08 | 2022-04-12 | 安徽华塑股份有限公司 | Polyvinyl chloride alloy preparation facilities |
| CN114522778A (en) * | 2022-03-03 | 2022-05-24 | 黄河水利职业技术学院 | Civil engineering waste environment-friendly treatment device with anti-blocking system and treatment method thereof |
| CN116328686A (en) * | 2023-02-21 | 2023-06-27 | 江苏德鑫新材料科技有限公司 | Reaction kettle for preparing nano spherical silicon dioxide dispersion liquid |
| CN116328686B (en) * | 2023-02-21 | 2023-11-24 | 江苏德鑫新材料科技有限公司 | Reaction kettle for preparing nano spherical silicon dioxide dispersion liquid |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN213434390U (en) | Novel reaction device for anidulafungin key process | |
| CN110355680B (en) | Surface deburring equipment for manufacturing bearing steel balls | |
| CN207307754U (en) | Two-dimensional mixing machine | |
| CN211189971U (en) | High-efficient coating agitating unit | |
| CN112544705A (en) | Continuous preparation device and method for producing yoghourt by polymerizing whey protein | |
| CN106005509B (en) | It is a kind of can filling plurality of raw materials bottle placer | |
| CN110773070A (en) | Fermented soya bean blendor convenient to it is clean | |
| CN206762785U (en) | It is easy to the powder metallurgy raw material blending device of discharging | |
| CN107020350A (en) | A kind of mulling founding wet pan structure for casting processing puddle mixer | |
| CN106732073A (en) | A kind of powder metallurgy mixing device | |
| CN109569383A (en) | A kind of aquaculture feed agitating device | |
| CN205590019U (en) | Rotation type button conveying equipment | |
| CN209696721U (en) | Mixing device is used in a kind of production of manganese-silicon | |
| CN107931623A (en) | A kind of plasma powder by atomization device | |
| CN208540608U (en) | A kind of floatation type aquaculture device | |
| CN204997532U (en) | Cartridge throw ball device | |
| CN208082297U (en) | A kind of triple stirring saponification machines | |
| CN207237803U (en) | A kind of agitating device | |
| CN204911314U (en) | Novel refractory material rolls agitator | |
| CN201366360Y (en) | Superfine smashing and grinding device | |
| CN210694852U (en) | Batch type coating machine | |
| CN209501828U (en) | A kind of mica edge runner | |
| CN208786420U (en) | A kind of floating agent synthesis agitating device | |
| CN206793541U (en) | One kind stirs sufficient breeding feed mixer | |
| CN111778369A (en) | Energy-saving vacuum leather tanning rotary drum |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20221228 Address after: No. 8, Weiyi Road, Anqing Hi tech Industrial Development Zone, Anqing City, Anhui Province 246000 Patentee after: ANQING CHICO PHARMACEUTICAL CO.,LTD. Address before: Room 1017, building F6, No.9, Weidi Road, Xianlin University Town, Xianlin street, Qixia District, Nanjing City, Jiangsu Province, 210000 Patentee before: NANJING CHICO PHARMACEUTICAL CO.,LTD. |