CN213409764U - Biological safety cabinet for nucleic acid extraction - Google Patents

Biological safety cabinet for nucleic acid extraction Download PDF

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Publication number
CN213409764U
CN213409764U CN202022219860.8U CN202022219860U CN213409764U CN 213409764 U CN213409764 U CN 213409764U CN 202022219860 U CN202022219860 U CN 202022219860U CN 213409764 U CN213409764 U CN 213409764U
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China
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cabinet
nucleic acid
cabinet body
acid extraction
baffle
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CN202022219860.8U
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Chinese (zh)
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李海玲
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45 Technology Beijing Co ltd
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45 Technology Beijing Co ltd
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Abstract

The utility model relates to a biosafety cabinet that can be used to nucleic acid to draw belongs to the safety cabinet field, can block biosafety cabinet's partial return air inlet to nucleic acid extraction appearance, arouses that the air that mixes the virus overflows the safety cabinet, and harm operating personnel healthy problem provides following technical scheme, and the technical essential of this application includes the cabinet body, high efficiency filter and exhaust system, the cabinet body is provided with has one side open-ended draft chamber, the cabinet body is provided with can open and close draft chamber open-ended glass door, its characterized in that, cabinet body outside is provided with the cabinet of accomodating that can hold nucleic acid extraction appearance, it is provided with one side open-ended and holds the chamber to accomodate the cabinet, the cabinet body is provided with the through-hole in its and the chamber open-ended coincidence department that holds, it is linked together with. This application has the advantage that reduces sheltering from of nucleic acid extraction appearance to the return air inlet, reduces the inside gaseous outside overflow of biosafety cabinet in the testing process.

Description

Biological safety cabinet for nucleic acid extraction
Technical Field
The application relates to the field of safety cabinets, in particular to a biological safety cabinet capable of being used for nucleic acid extraction.
Background
The biological safety cabinet is a box-shaped air purification safety device which is used for manufacturing an air barrier through a high-efficiency filter, an exhaust system and the like, protecting operators, experimental samples and operating environment and preventing aerosol from dissipating due to the fact that some dangerous or unknown biological particles are contained in the experimental operation and treatment process. The safety cabinet can be used for the safety protection of local working environment for medical institutions, and can also be applied to relevant industries such as biological laboratories, chemical experiments, biological pharmacy and the like.
The "new protocol for diagnosis and treatment of coronavirus pneumonia" clearly indicates, starting from the first edition: the novel coronaviruses are sensitive to ultraviolet light and all new corona tests are performed in biosafety cabinets. Many users place the nucleic acid extraction appearance in the biosafety cabinet, because the specification of nucleic acid extraction appearance is great, the nucleic acid extraction appearance can block the partial return air inlet of biosafety cabinet, make wind direct action on the nucleic acid extraction appearance, easily carry the virus that detects on the nucleic acid extraction appearance in the wind, the wind direction changes easily under the effect of nucleic acid extraction appearance simultaneously, flow to the outside of biosafety cabinet by the direction of original flow direction return air inlet, cause the air that mixes the virus easily to spill over the safety cabinet, harm operating personnel's is healthy.
SUMMERY OF THE UTILITY MODEL
Aiming at the defects existing in the prior art, the application aims to provide the biological safety cabinet for nucleic acid extraction, which has the advantages of reducing the shielding of a nucleic acid extraction instrument on an air return port and reducing the outward overflow of the gas inside the biological safety cabinet in the detection process.
The technical purpose of the application is realized by the following technical scheme:
the utility model provides a biosafety cabinet that can be used to nucleic acid and draw, includes the cabinet body, high efficiency filter and exhaust system, the cabinet body is provided with one side open-ended ventilation chamber has, the cabinet body is provided with can opens and close ventilation chamber open-ended glass door, a serial communication port, the external portion of cabinet is provided with the cabinet of accomodating that can hold the nucleic acid extraction appearance, it is provided with one side open-ended and holds the chamber to accomodate the cabinet, the cabinet body is provided with the through-hole in its and the coincidence department that holds the chamber open-ended, it is linked together with the ventilation chamber to hold.
By adopting the technical scheme, the nucleic acid extractor is placed in the storage cabinet, the storage cabinet is communicated with the cabinet body, so that the nucleic acid extractor is arranged at an air return opening of the cabinet body without shielding, when the nucleic acid extractor is required to be used for detection, the nucleic acid extractor is pulled out from the opening of the storage cabinet, part of the nucleic acid extractor is positioned in the storage cabinet, and part of the nucleic acid extractor is positioned in the cabinet body, so that a detection substance is placed in the nucleic acid extractor while the air purification safety function of the cabinet body is kept, then the nucleic acid extractor is reversely pushed into the storage cabinet, the substance is detected by the nucleic acid extractor, in the detection process, the interior of the cabinet body is always kept in a state of filtering air and circulating the air, in the detection process, the circulating air in the cabinet body is not in contact with the nucleic acid extractor, and therefore the change of the wind direction in the cabinet body by the nucleic acid extractor is reduced, and the setting of nucleic acid extraction appearance does not have the setting to the inside return air inlet department of the cabinet body and shelters from, reduces the inside gas of biological safety cabinet and outwards spills over in the testing process, improves the safety in utilization of the cabinet body.
The application is further configured to: the cabinet body is provided with a shielding device capable of opening and closing the through hole at the through hole.
Through adopting above-mentioned technical scheme, shelter from the separation that the device realized between the cabinet body and the cabinet of accomodating through setting up, avoid when not using the nucleic acid extraction appearance, the nucleic acid extraction appearance is polluted to other medicaments of the internal portion of cabinet.
The application is further configured to: the shielding device comprises a baffle and two guide rails, the guide rails are arranged along the movement direction of the baffle, the two guide rails are respectively arranged on two sides of the baffle and are in sliding connection with the guide rails, and the shielding device further comprises a driving mechanism used for driving the baffle to move along the length direction of the guide rails.
Through adopting above-mentioned technical scheme, through the length direction motion of actuating mechanism control baffle along the guide rail, the baffle can realize sheltering from convenient operation to through-hole department at the in-process of motion. Through the setting of two guide rails, can increase the stability of baffle motion in-process.
The application is further configured to: the driving mechanism comprises two mounting seats fixedly arranged on the cabinet body, the two mounting seats are oppositely arranged and two rotating shafts are arranged between the mounting seats, the rotating shafts and the guide rails are perpendicularly arranged, lifting ropes are wound on the rotating shafts, one ends, far away from the rotating shafts, of the lifting ropes are fixedly connected with the baffle, and the cabinet body is provided with a limiting assembly capable of limiting the rotation of the rotating shafts.
Through adopting above-mentioned technical scheme, remove the rotation restriction of spacing subassembly to the pivot, the baffle of pulling downwards, the baffle passes through the lifting rope and drives the pivot rotation, when the baffle covers in through-hole department completely, prescribes a limit to the pivot again through spacing subassembly, realizes prescribing a limit to the position of baffle.
The application is further configured to: the limiting assembly comprises a gear arranged on the rotating shaft and a limiting protrusion arranged on the mounting seat, a plurality of teeth are arranged at the edge of the gear, a tooth socket is formed by adjacent teeth in a surrounding mode, the limiting protrusion can be inserted into the tooth socket, and the mounting seat is provided with a telescopic adjusting assembly capable of driving the limiting protrusion to be far away from or close to the tooth socket.
Through adopting above-mentioned technical scheme, the in-process of pulling the baffle downwards, baffle drive pivot rotates, the pivot drives the synchronous rotation of gear simultaneously, make tooth extrusion flexible adjusting part, spacing arch deviates from the tooth's socket this moment, when the gear revolve to tooth's socket and spacing arch correspond, spacing arch reinserts the inside in tooth's socket under flexible adjusting part's effect, when stopping the effect to the baffle, under the effect of spacing arch and tooth's socket, can realize the fixed of baffle in optional position department.
The application is further configured to: the flexible adjusting part is including setting firmly in the locating piece of mount pad, the locating piece is the cavity setting, the inside of locating piece is provided with the movable rod, the one end of movable rod extend to the outside of locating piece and with spacing protruding fixed connection, the movable rod is kept away from and is had the activity space between spacing bellied one end and the locating piece inner wall in advance, the locating piece is provided with the elasticity that can keep spacing arch and tooth's socket grafting state and resets.
Through adopting above-mentioned technical scheme, when tooth acted on spacing protruding, spacing protruding drive the movable rod to keeping away from the one side motion of gear, when spacing protruding and tooth's socket alignment, drive movable rod and spacing protruding normal position that restores to the throne under the effect of elasticity piece that resets, make the inside of spacing protruding insertion tooth's socket.
The application is further configured to: the elastic reset piece is arranged in the positioning block, and one end of the elastic reset piece is fixedly connected with the positioning block, and the other end of the elastic reset piece is fixedly connected with the movable rod.
Through adopting above-mentioned technical scheme, make the elastic deformation of elasticity piece that resets can change along the length direction of locating piece, realize the direction to elasticity piece deformation that resets to keep movable rod along its axis direction reciprocating motion.
The application is further configured to: the mounting seat is provided with a return elastic piece for driving the rotating shaft to rotate reversely, one end of the return elastic piece is fixedly connected with the mounting seat, and the other end of the return elastic piece is fixedly connected with the rotating shaft; the locating piece is provided with a locating piece capable of limiting the position of the movable rod.
Through adopting above-mentioned technical scheme, when the sheltering from of baffle to through-hole department needs to be relieved, relieve the position restriction of setting element to the movable rod, drive pivot antiport under the effect of replying the elastic component, need not manual drive pivot antiport, can realize the promotion to the baffle to relieve the sheltering from of baffle to through-hole department.
The application is further configured to: the contact end of the storage cabinet and the nucleic acid extractor is provided with a plurality of rolling parts which are arranged side by side along the movement direction of the nucleic acid extractor.
Through adopting above-mentioned technical scheme, reduce the frictional force between cabinet and the nucleic acid extraction appearance of accomodating to reduce the in-process of removing the nucleic acid extraction appearance and to the damage of nucleic acid extraction appearance.
The application is further configured to: the cabinet body is provided with anti-skidding bulges at the through holes.
Through adopting above-mentioned technical scheme, dynamics is too big when avoiding the pull nucleic acid extraction appearance, reduces to take out the condition of accomodating the cabinet with the transition of nucleic acid extraction appearance.
In summary, the present application has the following beneficial effects:
firstly, the nucleic acid extractor is placed inside the storage cabinet, so that circulating air inside the cabinet body is not in contact with the nucleic acid extractor in the detection process, the change of the nucleic acid extractor to the wind direction inside the cabinet body is reduced, meanwhile, the nucleic acid extractor is arranged to shield an air return opening inside the cabinet body, the outward overflow of gas inside the biological safety cabinet in the detection process is reduced, and the use safety of the cabinet body is improved;
secondly, the separation between the cabinet body and the storage cabinet is realized by arranging the shielding device, so that the nucleic acid extractor is prevented from being polluted by other medicaments in the cabinet body when the nucleic acid extractor is not used;
thirdly, through the sliding connection between nucleic acid extraction appearance and the storage cabinet, reduce the frictional force between storage cabinet and the nucleic acid extraction appearance to reduce the damage to the nucleic acid extraction appearance of the in-process of removing the nucleic acid extraction appearance.
Drawings
FIG. 1 is a schematic diagram of the overall structure of an embodiment of the present application;
FIG. 2 is a top view of FIG. 1;
FIG. 3 is a sectional view taken along line A-A in FIG. 2;
FIG. 4 is a schematic view illustrating a connection relationship between the storage cabinet, the side wall of the cabinet body, and the baffle according to an embodiment of the present application;
FIG. 5 is an enlarged view of portion B of FIG. 4;
FIG. 6 is a top view of a schematic diagram illustrating the connection among the telescoping adjustment assembly, gears, and stop bosses according to an embodiment of the present disclosure;
fig. 7 is a sectional view taken along line C-C in fig. 6.
In the figure, 11, a cabinet body; 111. a ventilation cavity; 1111. a first chamber; 1112. a second chamber; 112. an air inlet; 113. an air duct; 114. a through hole; 12. an exhaust system; 13. a high efficiency filter; 131. an exhaust air filter; 132. an air supply filter; 14. a fan; 2. a storage cabinet; 21. an accommodating chamber; 22. mounting grooves; 31. a rolling member; 32. anti-skid projections; 33. an ultraviolet lamp; 41. a baffle plate; 42. a guide rail; 431. a mounting seat; 432. a rotating shaft; 433. a lift cord; 4331. a lifting section; 51. a gear; 511. teeth; 512. a tooth socket; 52. a limiting bulge; 53. a telescopic adjustment assembly; 531. positioning blocks; 532. a movable rod; 5321. a pressing plate; 533. a compression spring; 54. a coil spring; 55. a positioning member; 61. a first steering ring; 62. a second steering ring; 7. and a limiting plate.
Detailed Description
The present application is described in further detail below with reference to the attached drawings.
Referring to fig. 1, a biosafety cabinet for nucleic acid extraction disclosed in the present application includes a cabinet body 11, and a ventilation cavity 111 is disposed inside the cabinet body 11.
With reference to fig. 2 and 3, the ventilation cavity 111 includes a first chamber 1111 and a second chamber 1112, the first chamber 1111 is located below the second chamber 1112, a partition is disposed between the first chamber 1111 and the second chamber 1112, an exhaust system 12 is installed in the first chamber 1111, and the exhaust system 12 can accurately measure the air flow toxicity and the downdraft flow velocity flowing into the first chamber 1111, so as to provide protection for the laboratory operator and the detection sample.
Referring to fig. 3, the second chamber 1112 is a cavity having one side opened, the high efficiency filter 13 is installed in the second chamber 1112, and the high efficiency filter 13 includes the discharge filter 131 and the blower filter 132. The top wall of the cabinet body 11 is provided with an air outlet, the air outlet is communicated with an air outlet of the air exhaust filter 131, the air supply filter 132 is positioned below the air exhaust filter 131, the side wall of the cabinet body 11 is correspondingly provided with an air inlet 112, the air inlet 112 is communicated with the first chamber 1111, and the air inlet 112 is positioned below the air supply filter 132.
Referring to fig. 3, an air duct 113 is disposed on an inner side wall of the cabinet 11, one end of the air duct 113 is communicated with the first chamber 1111, the other end is provided with the fan 14, and an air outlet of the fan 14 is communicated with the second chamber 1112. The fan 14 is started, air in the first chamber 1111 enters the air duct 113, the air is pressurized by the fan 14 and enters the second chamber 1112, and partial air in the second chamber 1112 enters the first chamber 1111 through the air supply filter 132, so that a product to be detected can be protected; part of the air is exhausted out of the cabinet body 11 through the exhaust filter 131, so that the environment can be protected. The fan 14 draws air in the first chamber 1111 through the air duct 113, so that the first chamber 1111 is in a negative pressure state, and air outside the cabinet 11 enters the inside of the cabinet 11 through the opening of the cabinet 11. The negative pressure airflow sucked inward by the first chamber 1111 is used for protecting the safety of the operator.
Referring to fig. 3, the cabinet body 11 is installed at the opening and can be opened and close 111 open-ended glass doors in the ventilation chamber, and the glass doors can slide along the vertical length direction of the cabinet body 11, and the glass doors and the cabinet body 11 are slidably connected, so that the airtight state inside the cabinet body 11 can be ensured, and the polluted gas inside the cabinet body 11 is prevented from overflowing to the outside of the cabinet body 11 through the opening of the cabinet body 11.
With reference to fig. 1 and 3, a through hole 114 with a rectangular shape is formed in the side wall of the cabinet body 11, a storage cabinet 2 is welded to the outer wall of the cabinet body 11 at the edge of the through hole 114, the storage cabinet 2 is arranged with a rectangular shape, a containing cavity 21 with an opening on one side is formed inside the storage cabinet 2, and a nucleic acid extractor can be placed inside the containing cavity 21. The open end of the storage cabinet 2 faces the through hole 114 of the cabinet body 11, the storage cabinet 2 is communicated with the cabinet body 11, the accommodating cavity 21 is communicated with the ventilating cavity 111, and the nucleic acid extractor can be pulled at one side of the opening of the cabinet body 11, so that the part of the nucleic acid extractor is positioned in the cabinet body 11 and the part of the nucleic acid extractor is positioned in the storage cabinet 2, and a sample to be detected can be placed in the nucleic acid extractor under the protection of the cabinet body 11. Be provided with the stiffener between the cabinet 2 and the cabinet body 11, the one end and the cabinet body 11 fixed connection of stiffener, the other end and the lateral wall fixed connection of cabinet 2 are accomodate, realize the support to accomodating cabinet 2.
Referring to FIG. 4, a plurality of rollers 31 are rotatably mounted on the bottom wall of the storage case 2 and the contact surface of the nucleic acid extracting instrument, and the plurality of rollers 31 are arranged side by side from the bottom wall of the storage chamber 21 to the open end of the storage chamber 21.
With reference to fig. 4 and 5, the rolling member 31 includes a rolling shaft, the axial direction of the rolling shaft and the movement direction of the nucleic acid extraction instrument are perpendicular to each other, the bottom wall of the storage cabinet 2 is provided with a mounting groove 22, the rolling shaft is mounted in the mounting groove 22, the two ends of the rolling shaft are respectively integrally formed with a rotating shaft, the storage cabinet 2 is provided with a rotating hole matched with the rotating shaft on the side wall of the mounting groove 22, and the rotating shaft is rotatably connected in the rotating hole.
With reference to fig. 4 and 5, the bottom wall of the storage cabinet 2 is adhered with the anti-slip protrusions 32 on one side close to the through holes 114, when the nucleic acid extractor is pulled outwards, the bottom surface of the nucleic acid extractor contacts with the anti-slip protrusions 32, so that the movement transition of the nucleic acid extractor is avoided, and the nucleic acid extractor is prevented from being completely separated from the storage cabinet 2.
Referring to fig. 1, an ultraviolet lamp 33 is installed on a top wall of the storage cabinet 2, and the ultraviolet lamp 33 can sterilize the inside of the storage cabinet 2.
Referring to fig. 4, the cabinet 11 is provided with a shielding device at the through hole 114 for opening and closing the through hole 114. The shutter device includes a shutter 41 and a guide rail 42, and a driving mechanism that drives the shutter 41 to move along a longitudinal direction of the guide rail 42.
Referring to fig. 4, the guide rails 42 are disposed on the inner side wall of the cabinet 11, the number of the guide rails 42 is two, the two guide rails 42 are disposed on two sides of the through hole 114 respectively, the two guide rails 42 are disposed oppositely and in parallel, the length direction of the guide rails 42 is disposed along the vertical length direction of the cabinet 11, the guide rails 42 include a connecting portion and a shielding portion, the shielding portion is disposed in parallel with the side wall of the cabinet 11, one end of the connecting portion is fixedly connected with the side wall of the cabinet 11, the other end of the connecting portion is integrally formed with the shielding portion, the shielding portion and the connecting portion are integrally disposed in an L.
Referring to fig. 4, baffle 41 transversely strides the interval of locating between two guide rails 42, and the both sides of baffle 41 are pegged graft respectively in the inside of its guide rail 42 open end that corresponds, baffle 41 and guide rail 42 sliding connection, and baffle 41 is the rectangle setting, and when baffle 41 covered in through-hole 114, will accomodate cabinet 2 and cabinet 11 and separate, avoids nucleic acid extraction instrument when not using, and the inside pollutant of cabinet 11 gets into and accomodates the inside pollution nucleic acid extraction instrument of cabinet 2.
Referring to fig. 5, the driving mechanism includes a mount 431, a rotating shaft 432, a lift cord 433, and a stopper assembly that restricts the rotation of the rotating shaft 432.
Referring to fig. 5, the two mounting seats 431 are fixedly mounted on the inner side wall of the cabinet 11, the mounting seats 431 are disposed on one side close to the opening of the cabinet 11, the two mounting seats 431 are opposite and spaced, the rotating shaft 432 is rotatably disposed between the two mounting seats 431, and two ends of the rotating shaft 432 are respectively rotatably connected with the corresponding mounting seats 431.
Referring to fig. 4 and 5, the lifting cord 433 is wound around the outside of the rotating shaft 432, one end of the lifting cord 433 is fixedly connected to the rotating shaft 432, the other end extends to one side that is close to cabinet 11 roof, cabinet 11 inner wall fixed mounting has first steering ring 61, first steering ring 61 sets up directly over pivot 432, cabinet 11 inner wall fixed mounting has second steering ring 62 directly over baffle 41, the distance between second steering ring 62 and the preceding cabinet 11 diapire equals the distance between first steering ring 61 and the cabinet 11 diapire, the one end that the pivot 432 was kept away from to lifting rope 433 wears to locate in proper order behind first steering ring 61 and the second steering ring 62 equally divide into three-section promotion section 4331, the tip of three-section promotion section 4331 and the up end fixed connection of baffle 41, three-section promotion section 4331 sets up along the width direction of baffle 41 equidistant, improve the stability in the baffle 41 motion process, realize the steady promotion to baffle 41.
Referring to fig. 5, the limit assembly includes a gear 51, a limit protrusion 52, a telescopic adjustment assembly 53, a restoring elastic member, and a positioning member 55.
Referring to fig. 5, the gear 51 is disposed on the side of the mounting seat 431 close to the opening of the cabinet 11, and the end of the rotating shaft 432 is inserted through the mounting seat 431 close to the opening of the cabinet 11 and then is keyed to the axis of the gear 51. The gear 51 has a plurality of teeth 511 extending in a radial direction thereof, the plurality of teeth 511 are arranged at equal intervals in a circumferential direction of the gear 51, and a tooth space 512 is defined between adjacent teeth 511.
Referring to fig. 5, one end of the rotating shaft 432, which is far away from the gear 51, penetrates through the other mounting seat 431 and extends to one side close to the flap 41, the restoring elastic member is a coil spring 54, one end of the coil spring 54 is fixedly connected with the mounting seat 431, the other end of the coil spring is fixedly connected with the rotating shaft 432, and the rotating shaft 432 can automatically rotate in the reverse direction, so that the flap 41 is driven to restore to the original position.
Referring to fig. 6 and 7, the telescopic adjustment assembly 53 includes a positioning block 531, a movable rod 532, and an elastic restoring member.
Referring to fig. 7, the positioning block 531 is fixedly installed on the outer side of the installation seat 431 close to one side of the cabinet door, the positioning block 531 is arranged in a cylindrical shape, the axis of the positioning block 531 is perpendicular to the axis of the rotating shaft 432, the positioning block 531 is provided with a cavity along the axis direction thereof, the axis of the movable rod 532 coincides with the positioning axis, one end of the movable rod 532 is fixedly connected with the limiting protrusion 52, the other end of the movable rod 532 penetrates through the positioning block 531 and extends to the outside of the positioning block 531, and the movable rod 532 is.
Referring to fig. 7, the elastic restoring element is a compression spring 533, the compression spring 533 is disposed inside the positioning block 531, and the compression spring 533 is sleeved outside the movable rod 532. The movable rod 532 positioned inside the positioning block 531 extends along the radial direction thereof to form an extrusion plate 5321, the extrusion plate 5321 is arranged on one side of the movable rod 532 close to the limiting protrusion 52, an active space is reserved between the extrusion plate 5321 and the inner wall of the positioning block 531 far away from the limiting protrusion 52, the compression spring 533 is arranged inside the active space, one end of the compression spring 533 is fixedly connected with the extrusion plate 5321, and the other end of the compression spring 533 is fixedly connected with the positioning block 531. When the gear 51 rotates, the limiting protrusion 52 is pushed to move towards one side far away from the gear 51, the movable rod 532 drives the extrusion plate 5321 to extrude the compression spring 533, and when the limiting protrusion 52 is aligned with the tooth socket 512, the compression spring 533 drives the movable rod 532 to return to the original position, so that the limiting protrusion 52 is inserted into the tooth socket 512.
With reference to fig. 5 and 7, the positioning element 55 is disposed in a quadrangular prism shape, one side of the positioning block 531 close to the gear 51 is fixedly provided with a limiting plate 7, the limiting plate 7 is provided with a yielding hole in the middle thereof, the yielding hole is disposed in a rectangular shape, the inner diameter of the yielding hole is equal to the outer diameter of the positioning element 55, the positioning element 55 is slidably connected with the limiting plate 7, the outer wall of the movable rod 532 is correspondingly provided with a limiting hole, when the compression spring 533 is in a natural state, the end of the positioning element 55 penetrates through the yielding hole and is inserted into the limiting hole, so as to limit the movement of the movable rod 532.
The implementation principle of the embodiment is as follows: place the nucleic acid extraction appearance in the inside of accomodating cabinet 2, because accomodating cabinet 2 and cabinet body 11 are linked together for the setting of nucleic acid extraction appearance does not have the sheltering from to the return air inlet department of cabinet body 11. Before detection, the ultraviolet lamp 33 is started to sterilize the interior of the collection cabinet, then the ultraviolet lamp 33 is turned off, the nucleic acid extractor is manually pulled out of the storage cabinet 2 through one side of the opening of the cabinet body 11, the nucleic acid extractor is prevented from being completely separated from the storage cabinet 2 under the action of the anti-skid protrusions 32, so that the nucleic acid extractor is partially positioned in the storage cabinet 2 and partially positioned in the cabinet body 11, and a sample to be detected can be placed in the nucleic acid extractor under the protection of the cabinet body 11; then push the nucleic acid extraction appearance inside storage cabinet 2 in the reverse direction, detect the material through the nucleic acid extraction appearance, then remove the spacing of setting element 55 to movable rod 532, pulling baffle 41 downwards, when baffle 41 covers in through-hole 114 department, realize storage cabinet 2 and the separation of the cabinet body 11, at this moment, the inside state of ventilating to air filtration and wind circulation that remains throughout of the cabinet body 11, and in the testing process, the circulated air and the nucleic acid extraction appearance contactless of the inside of the cabinet body 11, thereby reduce the change of the inside wind direction of the cabinet body 11 of nucleic acid extraction appearance, and the setting of nucleic acid extraction appearance does not have the shelter from to the return air inlet department of the inside of the cabinet body 11, reduce the inside gas of biological safety cabinet in the testing process and outwards spill over, improve the safety in utilization of the cabinet body 11.
The embodiments of the present invention are preferred embodiments of the present application, and the scope of protection of the present application is not limited by the embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims (10)

1. The utility model provides a biosafety cabinet that can be used to nucleic acid and draw, includes the cabinet body (11), high efficiency filter (13) and exhaust system (12), the cabinet body (11) is provided with ventilation chamber (111) that have one side open-ended, the cabinet body (11) are provided with can open and close ventilation chamber (111) open-ended glass door, a serial communication port, cabinet body (11) outside is provided with accomodates cabinet (2) that can hold the nucleic acid extraction appearance, accomodate cabinet (2) and be provided with and have one side open-ended chamber (21) that holds, the cabinet body (11) are provided with through-hole (114) in its and the chamber (21) open-ended coincidence department that holds, it is linked together to hold chamber (21) and ventilation chamber (111).
2. The biosafety cabinet for nucleic acid extraction according to claim 1, wherein the cabinet body (11) is provided with a shielding device capable of opening and closing the through hole (114) at the through hole (114).
3. The biosafety cabinet for nucleic acid extraction according to claim 2, wherein the shielding device comprises a baffle (41) and two guide rails (42), the guide rails (42) are arranged along the movement direction of the baffle (41), the number of the guide rails (42) is two, the two guide rails (42) are respectively arranged on two sides of the baffle (41), the baffle (41) and the guide rails (42) are slidably connected, and the shielding device further comprises a driving mechanism for driving the baffle (41) to move along the length direction of the guide rails (42).
4. The biosafety cabinet for nucleic acid extraction according to claim 3, wherein the driving mechanism comprises two installation bases (431) fixedly arranged on the cabinet body (11), the two installation bases (431) are oppositely arranged, a rotating shaft (432) is rotatably arranged between the two installation bases (431), the rotating shaft (432) and the guide rail (42) are vertically arranged, a lifting rope (433) is wound on the rotating shaft (432), one end, far away from the rotating shaft (432), of the lifting rope (433) is fixedly connected with the baffle (41), and the cabinet body (11) is provided with a limiting component capable of limiting the rotation of the rotating shaft (432).
5. The biosafety cabinet for nucleic acid extraction according to claim 4, wherein the limiting assembly comprises a gear (51) arranged on the rotating shaft (432) and a limiting protrusion (52) arranged on the mounting seat (431), a plurality of teeth (511) are arranged at the edge of the gear (51), a tooth socket (512) is formed between adjacent teeth (511), the limiting protrusion (52) can be inserted into the tooth socket (512), and the mounting seat (431) is provided with a telescopic adjusting assembly (53) capable of driving the limiting protrusion (52) to be far away from or close to the tooth socket (512).
6. The biosafety cabinet for nucleic acid extraction according to claim 5, wherein the telescopic adjusting assembly (53) comprises a positioning block (531) fixedly arranged on the mounting seat (431), the positioning block (531) is arranged in a hollow manner, a movable rod (532) is arranged inside the positioning block (531), one end of the movable rod (532) extends to the outside of the positioning block (531) and is fixedly connected with the limiting protrusion (52), a movable space is reserved between one end of the movable rod (532) far away from the limiting protrusion (52) and the inner wall of the positioning block (531), and the positioning block (531) is provided with an elastic reset piece capable of keeping the insertion state of the limiting protrusion (52) and the tooth socket (512).
7. The biosafety cabinet for nucleic acid extraction according to claim 6, wherein the elastic reset piece is arranged inside the positioning block (531), one end of the elastic reset piece is fixedly connected with the positioning block (531), and the other end of the elastic reset piece is fixedly connected with the movable rod (532).
8. The biosafety cabinet for nucleic acid extraction according to claim 6, wherein the mounting seat (431) is provided with a restoring elastic member for driving the rotating shaft (432) to rotate reversely, one end of the restoring elastic member is fixedly connected with the mounting seat (431), and the other end of the restoring elastic member is fixedly connected with the rotating shaft (432); the positioning block (531) is provided with a positioning piece (55) capable of limiting the position of the movable rod (532).
9. A biosafety cabinet for nucleic acid extraction according to claim 1, wherein the storage cabinet (2) and the nucleic acid extractor are provided with a plurality of rolling members (31) at the contact end, and the plurality of rolling members (31) are arranged side by side along the movement direction of the nucleic acid extractor.
10. The biosafety cabinet for nucleic acid extraction according to claim 1, wherein the cabinet body (11) is provided with an anti-slip protrusion (32) at the through hole (114).
CN202022219860.8U 2020-09-29 2020-09-29 Biological safety cabinet for nucleic acid extraction Active CN213409764U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202022219860.8U CN213409764U (en) 2020-09-29 2020-09-29 Biological safety cabinet for nucleic acid extraction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202022219860.8U CN213409764U (en) 2020-09-29 2020-09-29 Biological safety cabinet for nucleic acid extraction

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CN213409764U true CN213409764U (en) 2021-06-11

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CN202022219860.8U Active CN213409764U (en) 2020-09-29 2020-09-29 Biological safety cabinet for nucleic acid extraction

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