CN213372181U

CN213372181U - Bile pancreatic duct tissue sampling device

Info

Publication number: CN213372181U
Application number: CN202020167289.7U
Authority: CN
Inventors: 王伟; 祁可; 金震东; 李兆申; 曹志强
Original assignee: Shanghai Futang Biotechnology Co ltd
Current assignee: Shanghai Futang Biotechnology Co ltd
Priority date: 2020-02-13
Filing date: 2020-02-13
Publication date: 2021-06-08
Anticipated expiration: 2030-02-13

Abstract

The utility model provides a bile pancreatic duct tissue sampling device, which comprises a handle, a sheath tube, a brush head and a miniature camera; wherein, a push-pull button on the handle is connected with the near end of the brush head through a push-pull rod; the sheath tube is sleeved outside the first push-pull rod, and the near end of the sheath tube is fixedly connected with the far end of the handle; adjusting a push-pull button to control the protrusion amount of the brush head relative to the distal end face of the sheath according to image information acquired by the miniature camera at the distal end of the sheath; a guide wire cavity is arranged in the sheath tube in parallel with the push-pull rod, and the distal end of the sheath tube is guided to enter the bile pancreatic duct by the guide wire penetrating into the guide wire cavity. The utility model discloses a cell brush examines technique and miniature camera shooting technique set to all set up in a sheath pipe, when realizing carrying out the cell brush under visual condition and examining, improve the security, carry the positive relevance ratio of courage pancreatic duct tumour, low in product cost can reduce patient's economic burden.

Description

Bile pancreatic duct tissue sampling device

Technical Field

The utility model relates to the field of medical equipment, especially, relate to a courage pancreatic duct tissue sampling device.

Background

In the prior art, when a living tissue sampling is carried out on a cholepancreatic duct cancer patient, two modes are mainly adopted, and the biopsy is carried out under the traditional X-ray positioning or cell brushing detection and the biopsy is carried out under the direct vision of a cholecystoscope/pancreatoscope.

The gallbladder and pancreatic duct biopsy under the guidance of X-ray has higher technical requirements on operators, and the positioning under the guidance of X-ray is not accurate enough, so that the three-dimensional positioning can not be realized, thereby often causing the conditions of low diagnosis sensitivity, high complication incidence rate and the like; the cell brushing detection under the guidance of X-ray has the advantages of relatively simple operation, low instrument cost and easy popularization. The defects are that the direction can not be accurately regulated during operation, the acquisition rate of cells or tissues with eccentric stenosis is relatively high, but the acquisition rate of cells or tissues with eccentric stenosis is relatively low, the diagnosis sensitivity is low, the operation is relatively difficult when the brush inspection is carried out on the stenosis at a special part, and the damage to the cholepancreatic duct is easily caused. The biopsy under direct vision of the bile duct/pancreatoscope has the advantages of direct vision judgment and accurate biopsy under direct vision, but has the defects of high price, high technical requirement on operators and the like, and meanwhile, due to the limitation of biopsy ducts of the bile duct/pancreatoscope, the used micro biopsy forceps have the advantages of extremely small tissue acquisition amount, high diagnosis sensitivity, low cost performance and no contribution to clinical popularization.

Biopsy or brush inspection under direct vision of a superfine gastroscope; performing cholecystoscopic biopsy or brushing inspection after percutaneous puncture; biopsy or brush test under an oral choledochoscope. The first approach is difficult to popularize clinically due to difficult manipulation, low success rates, or the need for special instruments such as anchoring balloon assistance. The second approach requires percutaneous puncture and is also less used clinically. The third method, along with the development of the oral choledochoscope, especially the second generation Spyglass, has been reported more and more for the diagnosis of pancreatic duct cancer.

The biopsy performed without direct visualization through an oral choledochoscope, which results are not ideal and may be related to the following reasons: 1. the fiber matrix of the biliary pancreatic duct cancer has more components, and the effective tumor tissues are too few; 2. only the lesion under the stenosis can be acquired; 3. the tissue taken is too small; 4. the specimen is not adequately processed. Therefore, the diagnostic value can be improved only by combining biopsy and direct visualization, and the diagnosis sensitivity is very high by combining NBI with the characteristics of tumor morphology, neovascularization and the like under direct visualization, and the current shortage is that expensive pancreatoscopy is required.

Therefore, it is an urgent need to provide a medical device which can provide a direct viewing condition, is convenient to operate, is safe and reliable, has low price and has high positive detection rate for the biliary pancreatic duct tumor.

SUMMERY OF THE UTILITY MODEL

The utility model provides a bile pancreatic duct tissue sampling device aiming at the defects of high price, difficult operation, inaccurate positioning and low positive rate of detected cancer cells in the prior art.

The utility model discloses a solve above-mentioned technical problem and adopt following technical scheme:

a bile pancreatic duct tissue sampling device comprises a handle, a sheath tube, a brush head and a miniature camera; the push-pull button on the handle is connected with the near end of the brush head through a push-pull rod; the sheath tube is sleeved outside the first push-pull rod, and the near end of the sheath tube is fixedly connected with the far end of the handle; adjusting the push-pull button to control the protruding amount of the brush head relative to the distal end face of the sheath according to the image information acquired by the miniature camera at the distal end of the sheath; and a guide wire cavity is arranged in the sheath tube in parallel to the push-pull rod, and the distal end of the sheath tube is guided to enter the cholecystokinesis duct by a guide wire penetrating into the guide wire cavity.

Preferably, the material of brush head is shape memory alloy, and the brush head is the arc.

Preferably, be close to sheath pipe distal end face establishes a set anchor, the set anchor imbeds completely in the sheath pipe outer wall, the one end of set anchor fixed connection pull wire, the other end of pull wire is worn out after sheath pipe outer wall extends a section distance along the proximal direction, passes the pull wire passageway that sets up in the sheath pipe wall is connected with the camber adjust knob on the handle.

Preferably, a rotating block is fixedly sleeved on the outer surface of the near end close to the push-pull rod, an opening is formed in the handle at a position corresponding to the rotating block, and the rotating block is rotated to drive the brush head to rotate.

Preferably, the brush head is provided with a plurality of bristles, and the bristles are inclined towards the far end or the near end.

Preferably, the pipe diameter of the sheath pipe is less than or equal to 3 mm.

Preferably, the interior of the sheath is configured as 2 or more than 2 channels.

Preferably, the sheath is internally structured into 3 cavities, which are divided into a brush head cavity, a guide wire cavity and a camera shooting cavity.

Preferably, the sheath is internally structured into 4 channels, which are divided into a brush head channel, a guide wire channel, a camera shooting channel and a water injection channel.

Preferably, the pipe diameter of the water injection cavity is 0.1-0.6 mm.

Preferably, the pipe diameter of the brush head cavity is 1-1.5 mm.

Preferably, the diameter of the micro camera is less than or equal to 1 mm.

The utility model adopts the above technical scheme, compare with prior art, have following technological effect:

(1) the cell brushing detection technology and the miniature camera shooting technology are integrated and are arranged in a sheath, so that the cell brushing detection is realized under a visual condition, the safety is improved, and the positive detection rate of the cholepancreatic duct tumor is improved;

(2) the expensive SPYglass superfine biliary endoscope is avoided, and the economic burden of a patient is reduced;

(3) the brushing inspection can be carried out on the cholepancreatic duct with narrow lower end of the combined cholepancreatic duct.

Drawings

FIG. 1 is a schematic structural view of a bile-pancreatic duct tissue sampling device of the present invention;

FIG. 2 is a sectional view taken along line A-A of FIG. 1 according to embodiment 1 of the present invention;

fig. 3 is a sectional view taken along line a-a of fig. 1 according to embodiment 2 of the present invention;

the reference numerals denote the description:

1-handle, 2-sheath tube, 3-push-pull rod, 4-brush head, 5-micro camera, 6-push-pull button, 7-water injection button, 8-water injection port, 9-brush head cavity channel, 10-guide wire cavity channel, 11-camera shooting cavity channel, 12-water injection cavity channel, 13-guide wire, 14-fixed anchor, 15-traction wire, 16-bending degree adjusting knob, 17-rotating block, 18-opening, 19-guide wire opening and 20-traction wire.

Detailed Description

The technical solution of the present invention will be further described in detail with reference to the accompanying drawings. In the following, distal refers to a position near the patient and proximal refers to a position near the operator.

Example 1

Referring to fig. 1, the present embodiment provides a sampling device for pancreatic duct tissue of gallbladder, which includes a handle 1, a sheath 2, a brush head 4 and a micro-camera 5; wherein, a push-pull button 6 on the handle 1 is connected with the near end of the brush head 4 through a push-pull rod 3; the sheath tube 2 is sleeved outside the first push-pull rod 3, and the near end of the sheath tube 2 is fixedly connected with the far end of the handle 1; according to the image information acquired by the miniature camera 5 at the far end of the sheath tube 2, the push-pull button 6 is adjusted to control the protruding amount of the brush head 4 relative to the far end face of the sheath tube 2; a guide wire cavity 10 is arranged in the sheath tube 2 in parallel to the push-pull rod 3, and the distal end of the sheath tube 2 is guided to enter the choledochus by a guide wire 13 penetrating into the guide wire cavity 10.

In this embodiment, the brush head 4 is made of shape memory alloy, the brush head 4 is arc-shaped, and the brush head 4 is rotated; under the condition of direct vision, the brush head 4 can be brushed and checked in a larger range.

In this embodiment, as shown in fig. 1-2, a fixing anchor 14 is disposed near the distal end surface of the sheath tube 2, the fixing anchor 14 is completely embedded in the outer wall of the sheath tube 2, the fixing anchor 14 is fixedly connected to one end of a pull wire 15, and the other end of the pull wire 15 penetrates through the outer wall of the sheath tube 2, extends for a distance along the proximal direction, and then passes through a pull wire channel disposed in the tube wall of the sheath tube 2 to be connected to a curvature adjusting knob on the handle 1; by stretching and releasing the pull wire 15, the distal end of the sheath 2 is controlled to bend, thereby controlling the micro-camera 5 and the brush head 4 to perform angular deflection.

In this embodiment, as shown in fig. 1, a rotating block 17 is fixedly sleeved on the outer surface of the proximal end close to the push-pull rod 3, an opening 18 is formed in the handle 1 at a position corresponding to the rotating block 17, and the brush head is driven to rotate by rotating the rotating block 17; further preferably, the inner surface of the rotation block 17 is fixed to the outer surface of the push-pull rod 3, and the position of the opening 18 is located at the position of the rotation block 17 when the protrusion amount of the distal end face of the brush head 4 relative to the distal end face of the sheath tube 2 is maximum.

In one embodiment of the present invention, the inner surface of the rotating block 17 is fixed to the outer surface of the push-pull rod 3, and the length of the opening 18 is consistent with the protruding amount of the distal end surface of the brush head 4 relative to the distal end surface of the sheath tube 2.

In an embodiment of the present invention, the position of the rotating block 17 and the opening 18 is kept fixed, the push-pull rod 3 is opposite to the proximal end segment of the rotating block 17 is provided with a stopper, the stopper is fixed and bonded with the push-pull rod by medical glue, the stopper is provided with a clamp lug, the proximal end face of the rotating block 17 is provided with a clamping groove matched with the stopper, when the distal end face of the brush head 4 is opposite to the protruding amount of the distal end face of the sheath tube 2 is maximum, the clamp lug of the stopper is inserted into the clamping groove of the rotating block 17, and the rotating block 17 is adjusted to drive the brush head to rotate.

In this embodiment, as shown in fig. 1, the brush head 4 is provided with a plurality of bristles, and the bristles are inclined towards the far end or the near end; preferably, the distal half of the bristles is inclined towards the proximal end, and the proximal half is inclined towards the distal end; furthermore, a circle of the brush head is divided into a plurality of uniform rows in the horizontal direction, and the inclination direction of each row of the brush hairs is different from that of the adjacent two rows of the brush hairs.

In this embodiment, as shown in fig. 2, the diameter of the sheath tube 2 is less than or equal to 3mm, and the sheath tube is made of PTFE polytetrafluoroethylene.

In the present embodiment, the sheath 2 is internally configured with 2 or more channels; preferably, as shown in fig. 2, the sheath has 3 channels, which are divided into a brush head channel 9, a guide wire channel 10 and a camera shooting channel 11; wherein, the guide wire cavity 10 not only can penetrate into the guide wire 13, but also can inject washing liquid through the guide wire cavity 10.

In this embodiment, as shown in FIG. 2, the diameter of the brush head channel 9 is 1-1.5 mm.

Example 2

Referring to fig. 1, the present embodiment provides a sampling device for pancreatic duct tissue of gallbladder, which includes a handle 1, a sheath 2, a brush head 4, a micro-camera 5 and a guide wire 13; wherein, a push-pull button 6 on the handle 1 is connected with the near end of the brush head 4 through a push-pull rod 3; the sheath tube 2 is sleeved outside the first push-pull rod 3, and the near end of the sheath tube 2 is fixedly connected with the far end of the handle 1; adjusting the push-pull button 6 to pull the brush head 4 to enter and exit the distal end surface of the sheath tube 2 according to the image information acquired by the miniature camera 5 at the distal end of the sheath tube 2; a guide wire cavity 10 is arranged in the sheath tube 2 in parallel to the push-pull rod 3, and the distal end of the sheath tube 2 is guided to enter the choledochus by a guide wire 13 penetrating into the guide wire cavity 10.

In the embodiment, the brush head (4) is made of shape memory alloy, the brush head (4) is arc-shaped, and the brush head (4) is rotated; under the condition of direct vision, the brush head (4) can be used for brushing and detecting in a larger range.

In this embodiment, as shown in fig. 1 and 3, a fixing anchor 14 is disposed near the distal end surface of the sheath tube 2, the fixing anchor 14 is completely embedded in the outer wall of the sheath tube 2, the fixing anchor 14 is fixedly connected to one end of a pull wire 15, and the other end of the pull wire 15 penetrates through the outer wall of the sheath tube 2 and extends a distance in the proximal direction, and then penetrates through a pull wire channel disposed in the tube wall of the sheath tube 2 to be connected to a curvature adjusting knob on the handle 1; by stretching and releasing the pull wire 15, the distal end of the sheath 2 is controlled to bend, thereby controlling the micro-camera 5 and the brush head 4 to perform angular deflection.

In this embodiment, as shown in fig. 1, the brush head 4 is provided with a plurality of bristles, and the bristles are inclined towards the far end or the near end; preferably, the distal half of the bristles is inclined towards the proximal end, and the proximal half is inclined towards the distal end; further, the brush head 4 is divided into a plurality of rows in the horizontal direction, and the inclination direction of each row is different from that of the adjacent two rows of bristles.

In this embodiment, as shown in fig. 3, the diameter of the sheath tube 2 is less than or equal to 3mm, and the sheath tube is made of PTFE polytetrafluoroethylene.

In the present embodiment, the sheath 2 is internally configured with 2 or more channels; preferably, as shown in fig. 3, the sheath 2 is internally configured with 4 channels, which are divided into a brush head channel 9, a guide wire channel 10, a camera shooting channel 11 and a water injection channel 12; furthermore, the diameter of the water injection cavity 12 is 0.1-0.6 mm. During operation, flushing fluid can be introduced into the water injection cavity 12 through the water injection port 8.

In this embodiment, as shown in fig. 2, the diameter of the brush head channel 9 is 1mm to 1.5 mm.

The present invention has been described in detail with reference to the specific embodiments, but the present invention is only by way of example and is not limited to the specific embodiments described above. Any equivalent modifications and substitutions to those skilled in the art are intended to be within the scope of the present invention. Accordingly, variations and modifications in equivalents may be made without departing from the spirit and scope of the invention, which is intended to be covered by the following claims.

Claims

1. A bile pancreatic duct tissue sampling device is characterized by comprising a handle (1), a sheath tube (2), a brush head (4) and a miniature camera (5); wherein a push-pull button (6) on the handle (1) is connected with the near end of the brush head (4) through a push-pull rod (3); the sheath tube (2) is sleeved outside the push-pull rod (3), and the near end of the sheath tube (2) is fixedly connected with the far end of the handle (1); a miniature camera (5) is arranged at the far end of the sheath tube (2), and the push-pull button (6) is adjusted to control the protruding amount of the brush head (4) relative to the far end face of the sheath tube (2) according to image information acquired by the miniature camera (5); a guide wire cavity (10) is arranged in the sheath tube (2) in parallel to the push-pull rod (3), and the far end of the sheath tube (2) is guided to enter the cholecystokinesis duct through a guide wire (13) penetrating into the guide wire cavity (10).

2. The cholepancreatic duct tissue sampling device of claim 1, wherein the material of the brush head (4) is a shape memory alloy and the brush head (4) is arc-shaped.

3. The pancreaticobiliary tissue sampling device according to claim 1, wherein a fixing anchor (14) is disposed near a distal end surface of the sheath (2), the fixing anchor (14) is completely embedded in an outer wall of the sheath (2), the fixing anchor (14) is fixedly connected to one end of a pull wire (15), and another end of the pull wire (15) passes through the outer wall of the sheath (2) and extends a distance in a proximal direction, and then passes through a pull wire channel disposed in a wall of the sheath (2) to be connected to a curvature adjusting knob (16) on the handle (1).

4. The cholepancreatic duct tissue sampling device according to claim 1, wherein a rotary block (17) is sleeved on the outer surface of the proximal end of the push-pull rod (3) in the handle (1), an opening (18) is formed in the outer surface of the handle (1) at a position corresponding to the rotary block (17), and the rotary block (17) is rotated to drive the brush head (4) to rotate.

5. The pancreaticovascular tissue sampling device of claim 1, wherein the brush head (4) is provided with a plurality of bristles, the bristles being inclined towards the distal or proximal end.

6. The cholepancreatic duct tissue sampling device according to claim 1, wherein the diameter of the sheath (2) is 3mm or less.

7. The pancreaticobiliary tissue sampling device of claim 1, wherein the sheath (2) is solid and has 2 or more lumens inside, and the lumens run from the proximal end of the sheath (2) to the distal end of the sheath (2).

8. The pancreaticobiliary tissue sampling device of claim 7, wherein the sheath (2) is internally configured with 3 lumens, divided into a brush head lumen (9), a guide wire lumen (10), and an imaging lumen (11).

9. The pancreaticobiliary tissue sampling device according to claim 7, wherein the sheath (2) is internally configured with 4 lumens, divided into a brush head lumen (9), a guide wire lumen (10), an image sensing lumen (11), and a water injection lumen (12).

10. The cholepancreatic duct tissue sampling device according to claim 9, wherein the water injection lumen (12) has a tube diameter of 0.1 to 0.6 mm.