CN213369891U - Device of aerosol generation or smog system or electron cigarette - Google Patents

Device of aerosol generation or smog system or electron cigarette Download PDF

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Publication number
CN213369891U
CN213369891U CN202020949689.3U CN202020949689U CN213369891U CN 213369891 U CN213369891 U CN 213369891U CN 202020949689 U CN202020949689 U CN 202020949689U CN 213369891 U CN213369891 U CN 213369891U
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communicated
atomizing
chamber
comparative example
nicotine
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钟术光
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Individual
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Priority claimed from CN201910470024.6A external-priority patent/CN110150760A/en
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    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10Devices using liquid inhalable precursors
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40Constructional details, e.g. connection of cartridges and battery parts
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/42Cartridges or containers for inhalable precursors

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Special Spraying Apparatus (AREA)

Abstract

The utility model discloses an aerosol generates or smog atomizing device, it includes 2 independent not communicating atomizing subsystems, atomizing subsystem includes a stock solution room respectively or holds the subassembly of chamber, an atomizer chamber, a fog or smog passageway or guide 1 and play the fog effect, above-mentioned stock solution room/or hold the chamber and directly communicate with each other or communicate through guide 2 with above-mentioned atomizer chamber, above-mentioned fog or smog passageway or guide 1 one end communicate with each other with above-mentioned atomizer chamber, its other end communicates with each other with a suction hole respectively, above-mentioned two stock solutions room/or hold the chamber and keep apart and do not communicate with each other, keep apart and do not communicate with each other between above-mentioned two atomizer chambers, keep apart and do not communicate with each other between above-mentioned two fog or smog passageway or guide 1, keep apart and do not communicate with each other between above-mentioned two guides 2.

Description

Device of aerosol generation or smog system or electron cigarette
Technical Field
The present invention relates to an aerosol generating or aerosolizing system or electronic cigarette and a device thereof, and more particularly, to an aerosol generating or aerosolizing system or electronic cigarette and a device thereof which are well experienced by consumers.
Background
In recent years, with the recognition of the harmful effects of smoking, government agencies and various health groups, as well as other interested organizations, have conducted numerous exercises and programs to advertise information about the adverse health effects caused by smoking. Moreover, as a result of the recognition of the deleterious effects, there have been many programs directed to attempting to reduce the incidence of smoking.
The most advantageous thing a severe smoker can do is to reduce or preferably even stop smoking completely. However, experiments have shown that most smokers find this extremely difficult, as most smokers are dependent on disease or addiction. WHO has a diagnosis in its international classification of disease called tobacco dependence. Others, for example, the american psychiatric society, are known as addictive nicotine dependence. It is generally accepted that these difficulties in stopping smoking are due to heavy smokers' dependence on nicotine.
Nicotine is an important material basis for the sensory quality of tobacco and tobacco products. Nicotine can act on the central nervous system of a human to cause corresponding physiological reaction, and the appropriate nicotine intake can refresh the brain, eliminate pain and increase nervous excitation, and can cause addiction after long-term use.
Nicotine administration can bring satisfaction by smoking, e.g., smoking a cigarette, cigar, or tube, or by smelling or chewing tobacco. However, smoking presents a serious health risk due to the formation of large amounts of harmful substances during the combustion of tobacco, such as carcinogenic tar products, carbon monoxide, aldehydes and hydrocyanic acid, and it is therefore desirable to create an alternative means of comfortable administration of nicotine, which can be used to promote withdrawal from smoking and/or replacement of smoking.
With the development of global smoking control activities, various relatively healthy cigarette/nicotine substitutes are emerging, among which electronic cigarettes (electronic cigarettes) are the most popular. The core part of the electronic cigarette is electronic cigarette oil (electronic cigarette liquid), which generates mist similar to real cigarette smoke under the action of the atomizer, but does not contain harmful substances such as tar, carbon monoxide and the like, and is well known.
At present, the main components of the electronic cigarette liquid are solvent (propylene glycol and glycerol, the total content is generally more than 90%), nicotine (the content is generally 0-3%) and flavor substances (different flavor components are added according to different tastes, such as tobacco, mint, coffee, fruits and the like). At present, most of electronic cigarette liquid sold in the market has the disadvantages of heavy sweet and greasy feeling in oral cavity after being smoked, weak tobacco fragrance and insufficient strength, can not meet the requirements of consumers, and seriously restricts the development of electronic cigarettes. The main reason for this is that the tobacco juice contains too little free nicotine.
Nicotine in electronic cigarettes exists in both free and bound forms. The strength of the cigarette is related to the content of nicotine in tobacco and mainstream smoke, and particularly has close relation with free nicotine in the tobacco. The physiological satisfaction of cigarette smoking is largely determined by the total amount of nicotine ingested and its rate of entry into the blood system. In 1970, Armitage et al found that free nicotine is more lipophilic than protic nicotine and is more readily penetrated through the oral mucosa and thus more rapidly absorbed by the body. The physical stimulation intensity and the smoke strength generated during smoking are related to the content of free nicotine in smoke, and the higher the content is, the larger the strength is.
Patent CN201510942417.4 discloses an electronic cigarette liquid containing a pH regulator, wherein the electronic cigarette liquid contains 1-10% of the pH regulator by mass, and the pH value of the electronic cigarette liquid is pH 7.2-pH 8.9. The electronic cigarette liquid improves the release amount of free nicotine and improves the physiological satisfaction of the electronic cigarette to a certain extent. However, nicotine is very easy to be oxidized and degraded, and is very easy to be volatilized and lost, and the throat-passing property and the oral property are not good.
Patent CN104473322A "discloses an electronic cigarette liquid containing nicotine and organic acids: uniformly mixing nicotine, organic acid and the electronic cigarette atomizing agent in proportion to obtain electronic cigarette liquid; wherein, the nicotine content in 1ml of electronic cigarette liquid is 1-30 mg; the organic acid is monocarboxylic acid or dicarboxylic acid; the molar ratio of monocarboxylic acid to nicotine is not more than 0.5 and the molar ratio of dicarboxylic acid to nicotine is not more than 0.25 ". The technology tries to make up for the uniformity of nicotine release by blending nicotine, organic acid and aerosol to form organic acid nicotine salt, and then evaporating the volatile organic acid or decomposing it into free nicotine through the heating process during the smoking of the electronic cigarette. However, in practice, this is difficult to occur because the nicotine salt degradation temperature is much higher than the boiling point of the atomizing agent (such as propylene glycol, glycerol or water or ethanol as mentioned), and the nicotine salt can only be atomized together with the atomizing agent, and even if heated to the degradation temperature of the nicotine salt, it is difficult to pyrolyze into nicotine, and more likely, many other pyrolysis products are generated, and the pyrolysis process is performed randomly within the molecule.
It should be especially pointed out that free nicotine is very easy to be oxidized and degraded, and is very easy to be volatilized and dissipated, and has strong throat choking feeling and pungent and spicy taste. The free nicotine content is increased, the throat passing performance of the electronic cigarette smoke liquid is deteriorated, and consumers may refuse to use the electronic cigarette smoke liquid, so that the resistance is generated. Although the nicotine salt has good stability and no throat choking feeling, the nicotine salt has bitter taste, poor mouthfeel and irritation, and is difficult to generate physiological satisfaction because the nicotine salt is too poor in lipophilicity and is difficult to be inhaled into the brain through mucous membranes.
Therefore, there is a need for an electronic cigarette that is stiff enough, has good physiological satisfaction, has low or no throat choking sensation, has low or no irritation, has good throat passing property, and has good use feeling for consumers.
Disclosure of Invention
The invention aims to provide the electronic cigarette device which is stiff, has good physiological satisfaction, low or no throat choking feeling, low or no irritation and good throat passing performance and is good for consumers to use and feel.
The invention relates to a device for aerosolizing or vaporizing or aerosolizing (a kit, device, unit) an electronic cigarette (or aerosol-generating system/material) comprising 2 separate, non-communicating aerosolizing subsystems, (respectively aerosolizing or vaporizing or aerosolizing (respectively) the above-mentioned compositions (i) and (ii) (or two different aerosol-generating materials)), which aerosolizing subsystems comprise respectively a reservoir/or holding chamber (and constituents thereof), an aerosolizing chamber (and constituents thereof), a vapour or smoke channel (and constituents thereof) or guide 1 and an aerosolizing or aerosol-generating component, said reservoir/holding chamber being in direct communication with said aerosolizing chamber or in communication via guide 2, said vapour or smoke channel or guide 1 communicating at one end with said aerosolizing chamber, the other ends of the two mist or smoke channels or guides 1 are respectively communicated with a suction (nozzle) hole, or the other ends of the two mist or smoke channels or guides 1 are jointly communicated with the suction (nozzle) hole after being converged near the suction (nozzle) hole (the definition of the vicinity is that the distance from the suction (nozzle) hole is not less than 70%, preferably 90%, more preferably 95%, most preferably 99% of the total length of the channels), or the other ends of the two mist or smoke channels or guides 1 are converged at the suction (nozzle) hole and communicated with the suction (nozzle) hole, the two liquid storage chambers/containing cavities are isolated and not communicated, the two atomization chambers are isolated and not communicated, the two mist or smoke channels or guides 1 are isolated and not communicated (except the suction (nozzle) hole or the definition of the vicinity), and the two guides 2 are isolated and not communicated. The atomization chamber can be a hollow continuous cavity or a non-continuous cavity, such as micropores in a material (such as non-woven fabric, ceramic, glass, metal and plastic) containing a plurality of micropores; the guide 2 may be a material containing fine pores (e.g., a nonwoven fabric containing fine pores, ceramics, glass, metal, or plastic), or may be a hollow introduction tube; the atomization component comprises a heating type (such as resistance heating type or electromagnetic (oscillation) heating type) or/and a vibration type (such as ultrasonic vibration type) or/and a compression type atomization component. Preferably a resistance heated component, in which electrical resistance converts electrical energy to thermal energy which heats the aerosol generating material when an electrical current is applied to the component. The heating element may be in the form of a wire mesh, a coil or a plurality of wires. The heating element may comprise a metal or metal alloy. Metals are excellent conductors of electrical and thermal energy. Suitable metals include, but are not limited to: copper, aluminum, platinum, tungsten, gold, silver, and titanium. Suitable metal alloys include, but are not limited to: nichrome and stainless steel. The liquid storage chamber/or the accommodating cavity can be in direct contact with the liquid storage, and can also be in indirect contact with the liquid storage, and the liquid storage chamber/the accommodating cavity accommodates another container containing the liquid storage, such as a cigarette cartridge.
The device used in the invention also comprises a housing, a power supply assembly, necessary accessories. Further, the device can also comprise a smoke cartridge, a control component and a (pneumatic) switch component. The shell is provided with a cigarette holder and a vent hole, the cigarette holder is provided with the mouth sucking hole, the vent hole is communicated with the air inlet hole of the atomizing chamber, and the air outlet hole of the atomizing chamber is communicated with the mist or smoke channel or the guide part 1. Preferably, the inner wall of the throat mouth is provided with a multi-stage (annular) containing cavity, so that the situation that a user cannot suck tobacco tar when sucking the cigarette holder can be avoided, and the smoker has better taste. Preferably, the inner port of the air inlet hole and/or the air outlet hole in the atomizing cavity is provided with a hole wall protruding out of the inner wall of the atomizing cavity, so that the tobacco tar generated by condensation in the atomizing cavity cannot directly flow out of the air outlet hole and be inhaled into the mouth of a user, a smoker can obtain better taste, and/or the tobacco tar is prevented from flowing out of the air inlet hole and the air outlet hole to cause the inner part or the outer surface of the electronic cigarette to be polluted.
The device for aerosolization or vaporization or aerosolization of the electronic cigarette (or aerosol-generating system/material) (described above) may be configured to heat the aerosol-generating material (compositions (i) and (ii) described above) to a temperature of about 50-500 or 450 ℃, 100-.
Examples of preferred devices for use in the present invention are:
example 1),
The mist outlet of an independent ultrasonic atomizer or a compression atomizer or a mesh atomizer is respectively communicated with the mist outlet of another independent ultrasonic atomizer or a compression atomizer or a mesh atomizer by two independent non-communicated guide tubes, the other end of each guide tube is communicated with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask which can be covered on the nose and the mouth, and a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity. Preferably, the tee joint is spaced from and not communicated with a branch pipe at one end which is communicated with an inhalation mask capable of covering the nose and the mouth.
Example 2),
An ultrasonic atomizer, a compression atomizer or a net atomizer comprises 2 independent and non-communicated atomizing subsystems, wherein mist outlets of the atomizing subsystems are respectively communicated by two independent and non-communicated guide tubes, the other ends of the guide tubes are communicated with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, or is communicated with the inhalation mask capable of covering the nose and the mouth by one (preferably, the middle part is not communicated with the middle part) guide tube, and a user can inhale mist or smoke in the inhalation mask through the inhalation mask by a nasal cavity or/and an oral cavity. Preferably, the tee joint is spaced from and not communicated with a branch pipe at one end which is communicated with an inhalation mask capable of covering the nose and the mouth.
Example 3),
2 electronic smoking sets with independent atomization systems are combined together to be directly used for oral inhalation, or the mist outlet of the combined electronic smoking sets is respectively communicated with two independent and non-communicated guide tubes (such as rubber tubes and silicone tubes) for oral inhalation, or the other ends of the two independent and non-communicated guide tubes are communicated with two branch tubes in a tee joint, and the branch tube at the other end of the tee joint is communicated with a guide tube which can be used for oral inhalation. The outer diameter of the above-mentioned catheter is usually 3mm to 12mm, preferably 4mm to 6 mm. Preferably, the catheter has a large end and a small end, the large outer diameter being 8mm to 12mm, the large outer diameter being 2mm to 5mm, and the small end being used for the mouth.
Example 4), an electronic smoking article comprising 2 independent non-communicating aerosolizing subsystems therein (kits, devices, units for aerosolizing or vaporizing or aerosolizing the electronic cigarette (or aerosol-generating system/material) described above), such as:
example 4-1),
An electronic cigarette (appliance) (a kit, device, unit) for aerosolizing or vaporizing or aerosolizing the electronic cigarette (or aerosol generating system/material) comprises a cigarette-shaped cavity housing (4), a power supply (2), a cartridge (3) and a rod attachment, wherein the power supply (2), a pneumatic switch (7), a high-frequency generator (8), a magnetostrictive vibrator (9) and an electromagnetic induction heater (10) with two separated cavities (liquid storage chambers/containing chambers) which are not communicated with each other or the pneumatic switch (7), the power supply (2), the high-frequency generator (8), the magnetostrictive vibrator (9) and the electromagnetic induction heater (10) with two separated cavities (liquid storage chambers/containing chambers) which are not communicated with each other are sequentially arranged in the housing from the front end to the rear end, wherein, the high-frequency generator (8) is respectively connected with the magnetostrictive vibrator (9), the electromagnetic induction heater (10) and the pneumatic switch (7) through leads;
a light emitting diode (6) is arranged at the front end of the shell (4) and is respectively connected with the pneumatic switch (7) and the power supply (2) through leads;
the rear end of the shell (4) is connected with the cartridge (3), and two cavities (liquid storage chambers/containing cavities) (31) which are separated from each other and are not communicated are arranged in the cartridge (3);
the fog or smoke channels in the (cigarette rod accessory of the) electronic cigarette are separated and not communicated with each other. (as shown in FIGS. 1-1, 3)
Preferably, the electronic cigarette further comprises a cigarette cap (1) which is arranged at the front end of the light-emitting diode (6) and covers the light-emitting diode (6).
Preferably, the power source (2) in the electronic cigarette is a rechargeable battery having a charging positive contact (21) and a charging negative contact (22).
Preferably, the magnetostrictive vibrator (9) in the electronic cigarette comprises: the electromagnetic induction heater comprises a magnetostrictive rod (93), wherein two ends of the magnetostrictive rod (93) are respectively provided with a permanent magnet (91), driving coils (92) are wound outside the magnetostrictive rod (93) and the two permanent magnets (91), and a vibration sensor (94) is arranged between the permanent magnet (91) and the electromagnetic induction heater (10). (as shown in FIGS. 1-2)
Preferably, the electromagnetic induction heater (10) in the electronic cigarette comprises: a vibrating plate (101) is fixedly connected to the shell (4) through external threads on the vibrating plate, a stainless steel tube (104) which is provided with two cavities (liquid storage chambers/accommodating cavities) and is spaced from each other is correspondingly arranged at the lower part of the vibrating plate, the two cavities (liquid storage chambers/accommodating cavities) of the stainless steel tube (104) are internally provided with nickel mesh wires (103), and an induction coil (102) is arranged between the stainless steel tube (104) and the shell (4). (as shown in FIGS. 1-2)
Preferably, the pneumatic switch (7) of the electronic cigarette comprises: an upper clamp body (71) and a lower clamp body (74) are butted together, wherein grooves are respectively arranged at the butted positions of the upper clamp body (71) and the lower clamp body (74), the outer edge of a silica gel leather bag (73) is arranged in each groove, the silica gel leather bag (73) is provided with a central hole, a magnet (72) is arranged in the central hole of the silica gel leather bag (73), a vent hole is arranged on the lower clamp body (74), a circuit board is arranged in the upper clamp body (71), and wire grooves for placing circuit board wires are arranged on the outer sides of the upper clamp body (71) and the lower clamp body (74). (as shown in FIGS. 1-4)
Preferably, the silica gel leather bag (73) in the electronic cigarette is provided with an air slit or an air hole.
Preferably, a human body clutter sensor (75), a data processor (76), a general control output circuit (77), an amplification output circuit (78) and an over-temperature over-current over-discharge protection circuit (79) are sequentially and serially arranged on the circuit board in the electronic cigarette, wherein the amplification output circuit (78) and the over-temperature over-current over-discharge protection circuit (79) are connected with an ultrasonic atomizer (70). (as shown in FIGS. 1-5)
Preferably, the cartridge (3) of the electronic cigarette comprises a housing (33) having a positioning boss (35) on the surface thereof, wherein a bayonet (32) with a middle interval and without communication, two smoke liquid return cavities (34) with a middle interval and without communication and two liquid storage chambers/or accommodating cavities (31) with a middle interval and without communication are sequentially arranged in the housing, and a cotton silk screen (36) with a middle interval and without communication is arranged at the outer end of the housing (33) and is used for preventing the smoke liquid from being sucked into the mouth of a user. (as shown in FIGS. 1-6)
Example 4-2),
An electronic cigarette (with) (a device (kits, device, unit) for aerosolization or vaporization or aerosolization of the above-mentioned electronic cigarette (or aerosol-generating system/material)), characterized in that the device comprises an outer housing, a mouthpiece, necessary accessories and an ultrasonic atomization device; two isolated and non-communicated mist or smoke channels are arranged in the outer shell and the cigarette holder, one end of each channel is communicated with the air outlet hole on the cigarette holder, and the other end of each channel is communicated with the mist outlet in the ultrasonic atomization device; the ultrasonic atomization device comprises an inner shell (10), a power supply (12), a liquid storage part (liquid storage chamber/or accommodating cavity) (14), a net-shaped member (20) and a vibration source (30), wherein the liquid storage part (liquid storage chamber/accommodating cavity) (14) is formed in the shell (10), the liquid storage part (liquid storage chamber/accommodating cavity) (14) (middle) is separated from each other, an openable liquid filling opening is formed in the upper end of the shell (10), a mist outlet is formed in the shell (used for storing liquid), the mist outlet and a mist or mist channel communicated with the mist outlet are separated from each other (middle), the net-shaped member (20) is embedded in the mist outlet, the net-shaped member (20) is a porous net-shaped structure with a plurality of fine holes (21), the vibration source (30) is connected with the net-shaped member (20), and the vibration source (30) is electrically connected with the power supply (12), the vibration source (30) can generate vibration after being electrified and drives the mesh component (20) to vibrate so as to vibrate and atomize the liquid near the mesh component (20); the micro holes (21) penetrate through the mesh-shaped member (20) so that the atomized liquid smoke can flow out along the micro holes (21), the mesh-shaped member (20) is electrically connected with the power supply (12), and the mesh-shaped member (20) can generate heat and atomize the liquid near the mesh-shaped member (20) by heating after being electrified. (as shown in FIGS. 2-1 and 2)
Preferably, the ultrasonic atomization device is characterized in that the vibration source (30) is at least partially positioned in the liquid storage part (14), and the end face of one end of the vibration source (30) is connected with the mesh member (20).
Preferably, the ultrasonic atomization device is characterized in that the vibration source (30) is located between the power source (12) and the liquid storage part (14) and one end of the vibration source (30) extends into the liquid storage part (14).
Preferably, the ultrasonic atomization device is used for an electronic cigarette, a partition plate (18) hermetically connected with the shell (10) is arranged in the shell (10), the partition plate (18) forms the bottom of the liquid storage part (14) in a closed mode, and one end of the vibration source (30) penetrates through the partition plate (18) upwards and extends into the liquid storage part (14).
Preferably, the ultrasonic atomizing device is characterized in that a cover liner (24) is arranged between the periphery of the mesh member (20) and the aerosol outlet of the liquid storage part (14), the mesh member (20) and the housing (10) are sealed by the cover liner (24), and the periphery of the mesh member (20) is abutted against the cover liner (24), so that the mesh member (20) can be kept in the cover liner (24) even when vibrating.
Preferably, the ultrasonic atomization device, wherein the longitudinal section of the liquid storage part (14) is in a concave shape, two gas mist channels (16) which are isolated from each other and are not communicated with each other are formed in the center of the liquid storage part (liquid storage chamber/or accommodating cavity) (14), one end of the fine hole (21) of the mesh member (20) is communicated with the liquid storage part (14), and the other end is communicated with the gas mist channel (16).
Preferably, the ultrasonic atomizing device is characterized in that the mesh member (20) is of a flat plate structure, the micropores (21) of the mesh member (20) are formed by gaps formed after the ribs (23) are arranged in a honeycomb shape, the micropores (21) have a large pore diameter at two ends and a small pore diameter at the middle, or the micropores (21) have a large pore diameter at one end and a small pore diameter at the other end, when the micropores (21) have a large pore diameter at one end and a small pore diameter at the other end, the end with a large pore diameter is a liquid inlet end communicated with the inside of the liquid storage part (14), and the end with a small pore diameter is an aerosol outlet end.
Preferably, the ultrasonic atomization device, wherein the mesh member (20) further comprises a metal mesh, the metal mesh comprises two layers, namely a top layer metal mesh arranged at the top of the mesh member (20) and a bottom layer metal mesh arranged at the bottom of the mesh member (20), and the ribs (23) are arranged between the bottom layer metal mesh and the top layer metal mesh at intervals and are electrically connected with the bottom layer metal mesh and the top layer metal mesh.
Preferably, the material of the mesh-shaped member (20) is a conductive anti-corrosion material.
Examples 4 to 3),
An integrated electronic cigarette (appliance) (a kit with an oil cup for aerosolizing or vaporizing or aerosolizing the electronic cigarette (or aerosol-generating system/material)) comprises a housing (1), and a control assembly (2), a battery (3) and an atomizer (4) disposed in the housing (1), wherein the control assembly (2) is electrically connected with the battery (3) and a heating wire (41) of the atomizer (4), respectively, and is characterized in that: an oil cup (a liquid storage chamber/or an accommodating cavity) (5) for accommodating smoke liquid is also arranged in the shell (1), the atomizer (4) and the oil cup (liquid storage chamber/or containing cavity) (5) are adjacently arranged, one end of the oil cup (5) close to the atomizer (4) is provided with a smoke liquid outlet (51), a material (such as non-woven fabric, ceramic, glass, metal and plastic) with micro holes inside, preferably a non-woven fabric (52) is packaged at the cigarette liquid outlet (51), the heating wire (41) of the atomizer (4) is arranged closely to the material (preferably non-woven fabric (52)) with the micro holes inside, two cavities (liquid storage chambers or accommodating cavities) which are separated from each other and are not communicated are arranged in the atomizer (4) and the oil cup (liquid storage chamber or accommodating cavity) (5), the smoke liquid outlet (51) and the mist or smoke channel (middle) communicated with the smoke liquid outlet are isolated and not communicated with each other. (as shown in FIG. 3-1)
Preferably, the aperture of the smoke liquid outlet (51) in the electronic cigarette is the same as the aperture of the oil cup (5).
Preferably, in the electronic cigarette, one end of the housing (1) is provided with (the middle of) two cigarette caps (11) which are not communicated with each other but through which smoke can pass through the pore channels respectively and are provided with the pore channel openings (i.e. the mouth sucking holes), the other end of the housing (1) is provided with a lamp cap (12) with an LED lamp, the control assembly (2) is fixed in the lamp cap (12), and the control assembly (2) comprises a control circuit board and a control switch.
Preferably, a first air inlet hole (121) is formed in a side surface of the lamp cover (12) of the electronic cigarette, and a control switch of the control assembly (2) is an air suction type automatic switch.
Preferably, in the electronic cigarette, the atomizer (4) includes an oil-separating silicone seat (42) and a connecting pipe (43) which is isolated from each other (in the middle) and does not communicate with each other but the smoke gas can pass through the connecting pipe respectively, the oil-separating silicone seat (42) is in interference fit with the housing (1), one end of the connecting pipe (43) abuts against the oil-separating silicone seat (42), the other end of the connecting pipe (43) abuts against a material (preferably a non-woven fabric (52)) with a micro-hole in the end face of the smoke liquid outlet (51), two chambers isolated from the connecting pipe (43) are respectively provided with a glass fiber rope (44), the heating wire (41) is wound on the glass fiber rope (44), the oil-separating silicone seat (42) is provided with two air inlets (or (in the middle) which are isolated from each other) (421) and are respectively communicated with the two chambers isolated from the connecting pipe (43), and the air inlets (421) are respectively communicated with the first air inlet (121), A suction nozzle hole on the cigarette nozzle cover (11) is communicated. (as shown in FIG. 3-1)
Examples 4 to 4),
An electronic smoking device (a kit for aerosolization or vaporization or aerosolization of the electronic cigarette (or aerosol-generating system/material) described above) comprising (upper and lower) housings, power supply components, necessary accessories and 2 separate, non-communicating aerosolization subsystems; the lower shell (cuboid) comprises a power supply component, an atomization subsystem and two isolated and non-communicated fog or smoke channels, wherein one end of each fog or smoke channel is communicated with the atomization subsystem, and the other end of each fog or smoke channel is communicated with the fog or smoke channels in the upper shell; the upper housing is a cigarette holder, the bottom of which is shaped as two sloping sides, preferably circular arc, connected to the lower housing, and the short bottom of which is provided with two air outlets, in which two isolated and non-communicating vapour or smoke channels are provided, one end of which communicates with said air outlets and the other end of which communicates with the vapour or smoke channel in said lower housing. Preferably, edges (edges) and/or corners of the upper and lower cases are rounded. Preferably, the mouth-sucking end of the upper shell is elongated to accommodate the need for suction. The upper shell mouthpiece extension may be cylindrical, square cylindrical, prismatic, or hammer-shaped.
The independent atomization subsystem respectively comprises a liquid storage chamber/or an accommodating cavity (and a component thereof), an atomization chamber (and a component thereof), a mist or smoke channel (and a component thereof) or a guide member 1 and an atomization component, wherein the liquid storage chamber/the accommodating cavity is directly communicated with the atomization chamber or is communicated with the atomization chamber through the guide member 2, the mist or smoke channel or the guide member 1 is a mist or smoke channel in the upper shell and the lower shell, the two liquid storage chambers/the accommodating cavities are isolated and not communicated, the two atomization chambers are isolated and not communicated, the two guide members 2 are isolated and not communicated, and the two mist or smoke channels or the guide member 1 are isolated and not communicated.
The compositions (I) and (II) are respectively placed in the two separated and non-communicated liquid storage chambers or containing cavities (or containing cavities), or the compositions (I) and (II) are respectively pre-placed in containers such as glass, ceramics, metal and the like, and then are placed in the two separated and non-communicated liquid storage chambers or containing cavities (or containing cavities) together with the containers.
The preferable technical scheme is as follows:
1. a device (kit, device, apparatus, unit) for the aerosolization or vaporisation or aerosolisation or aerosolization of an electronic cigarette (or aerosol-generating system/material), characterised in that the device comprises 2 independent, non-communicating aerosolization subsystems.
2. The device according to claim 1, wherein the atomizing subsystem comprises a liquid storage chamber and/or a containing chamber (and its components), an atomizing chamber (and its components), a mist or smoke channel (and its components) or a guide member 1, and an atomizing component, the liquid storage chamber and/or the containing chamber is directly communicated with the atomizing chamber or communicated with the atomizing chamber through a guide member 2, one end of the mist or smoke channel or guide member 1 is communicated with the atomizing chamber, and the other end thereof is communicated with a nozzle hole, or the other ends of the 2 mist or smoke channels or guide members 1 are communicated with a nozzle hole after being converged near the nozzle hole (defined as the distance from the nozzle hole is not less than 70%, preferably 90%, more preferably 95%, most preferably 99%) of the total length of the channel, or the other ends of the 2 fog or smoke channels or the guide parts 1 converge at a suction (nozzle) hole and are communicated with the suction (nozzle) hole, the two liquid storage chambers or the accommodating cavities are isolated and not communicated, the two atomization chambers are isolated and not communicated, the two fog or smoke channels or the guide parts 1 are isolated and not communicated (except the suction (nozzle) hole or the defined vicinity), and the two guide parts 2 are isolated and not communicated.
3. The device according to claim 2, characterized in that the atomising chamber is a hollow continuous volume.
4. The device according to claim 2, characterized in that said nebulization chamber is a discontinuous volume.
5. The apparatus according to claim 2, wherein the atomizing chamber is a fine hole in a material containing a plurality of fine holes.
6. The device according to claim 2, wherein the atomization chamber is a non-woven fabric, ceramic, glass, metal, or plastic having a plurality of micropores.
7. The device according to claim 2, characterized in that the guide 2 is a material containing microscopic pores.
8. The device according to claim 2, wherein the guide 2 is made of a nonwoven fabric, ceramic, glass, metal, or plastic containing fine pores.
9. The device according to claim 2, characterized in that the guide 2 is a hollow lead-in tube.
10. The device according to claim 2, characterized in that the atomizing means comprise heat-generating or/and vibrating or/and compression-type atomizing means.
11. The device according to claim 2, characterized in that the atomizing means comprise an electrically resistive or electromagnetically (oscillatory) heating or/and ultrasonically vibrating atomizing means.
12. The device according to claim 2, characterized in that it further comprises a housing, a power supply assembly, necessary accessories.
13. The device according to claim 12, characterized in that it further comprises a cartridge, a control unit, a (pneumatic) switch unit.
14. The device according to claim 12, characterized in that the housing is provided with a mouthpiece and a vent hole, the mouthpiece hole is located in the mouthpiece, the vent hole is communicated with an air inlet hole of the atomizing chamber, and an air outlet hole of the atomizing chamber is communicated with the mist or smoke channel or the guide member 1.
15. A device (kit) for the aerosolization or vaporization or aerosolization of an electronic cigarette (or aerosol generating system/material) is characterized by comprising a cigarette-shaped cavity housing (4), a power supply (2), a cartridge (3) and a tobacco rod accessory, wherein the power supply (2), a pneumatic switch (7), a high-frequency generator (8), a magnetostrictive vibrator (9) and an electromagnetic induction heater (10) with two liquid storage chambers/containing chambers which are separated from each other and are not communicated with each other or the pneumatic switch (7), the power supply (2), the high-frequency generator (8), the magnetostrictive vibrator (9) and the electromagnetic induction heater (10) with two liquid storage chambers/containing chambers which are separated from each other and are not communicated with each other are arranged in the housing from the front end to the rear end in sequence, wherein, the high-frequency generator (8) is respectively connected with the magnetostrictive vibrator (9), the electromagnetic induction heater (10) and the pneumatic switch (7) through leads;
the rear end of the shell (4) is connected with the cartridge (3), and two cavities (liquid storage chambers/containing cavities) (31) which are separated from each other and are not communicated are arranged in the cartridge (3);
the fog or smoke channels in the (cigarette rod accessory of the) electronic cigarette are separated and not communicated with each other.
16. The device according to the technical scheme 15 is characterized in that a light emitting diode (6) is arranged at the front end of the shell (4) and is respectively connected with the pneumatic switch (7) and the power supply (2) through leads.
17. The device according to claim 15, characterized in that the electronic cigarette further comprises a cap (1) disposed at the front end of the light emitting diode (6) to cover the light emitting diode (6) therein.
18. The device according to claim 15, characterized in that said power source (2) in said electronic cigarette is a rechargeable battery having a positive charging contact (21) and a negative contact (22).
19. The device according to claim 15, characterized in that said magnetostrictive vibrator (9) in said electronic cigarette comprises: the electromagnetic induction heater comprises a magnetostrictive rod (93), wherein two ends of the magnetostrictive rod (93) are respectively provided with a permanent magnet (91), driving coils (92) are wound outside the magnetostrictive rod (93) and the two permanent magnets (91), and a vibration sensor (94) is arranged between the permanent magnet (91) and the electromagnetic induction heater (10).
20. The device according to claim 15, characterized in that said electromagnetic induction heater (10) in said electronic cigarette comprises: a vibrating plate (101) is fixedly connected to the shell (4) through external threads on the vibrating plate, a stainless steel tube (104) which is provided with two cavities (liquid storage chambers/accommodating cavities) and is spaced from each other is correspondingly arranged at the lower part of the vibrating plate, the two cavities (liquid storage chambers/accommodating cavities) of the stainless steel tube (104) are internally provided with nickel mesh wires (103), and an induction coil (102) is arranged between the stainless steel tube (104) and the shell (4).
21. The device according to claim 15, characterized in that said pneumatic switch (7) in said electronic cigarette comprises: an upper clamp body (71) and a lower clamp body (74) are butted together, wherein grooves are respectively arranged at the butted positions of the upper clamp body (71) and the lower clamp body (74), the outer edge of a silica gel leather bag (73) is arranged in each groove, the silica gel leather bag (73) is provided with a central hole, a magnet (72) is arranged in the central hole of the silica gel leather bag (73), a vent hole is arranged on the lower clamp body (74), a circuit board is arranged in the upper clamp body (71), and wire grooves for placing circuit board wires are arranged on the outer sides of the upper clamp body (71) and the lower clamp body (74).
22. The device according to claim 15, characterized in that the silica gel bladder (73) in the electronic cigarette is provided with air gaps or air holes.
23. The device according to claim 15, characterized in that the circuit board of the electronic cigarette is provided with a human body clutter sensor (75), a data processor (76), a total control output circuit (77), an amplification output circuit (78) and an over-temperature over-current over-discharge protection circuit (79) which are connected in series in sequence, wherein the amplification output circuit (78) and the over-temperature over-current over-discharge protection circuit (79) are connected with an ultrasonic atomizer (70).
24. The device according to the technical scheme 15 is characterized in that the cigarette cartridge (3) in the electronic cigarette comprises a shell (33), a positioning boss (35) is arranged on the surface of the shell, a bayonet (32) which is spaced and not communicated with the shell, two cigarette liquid return cavities (34) which are spaced and not communicated with the shell and two liquid storage chambers/or accommodating cavities (31) which are spaced and not communicated with the shell are sequentially arranged in the shell, and a cotton silk screen (36) which is spaced and not communicated with the shell and is used for preventing the cigarette liquid from being sucked into a user's mouth is arranged at the outer end of the shell (33).
25. A device (kit, device, unit) for aerosolization or vaporization or aerosolization of an electronic cigarette (or aerosol-generating system/material), characterized in that the device comprises an outer housing, a mouthpiece, necessary accessories and an ultrasonic atomizing device; two isolated and non-communicated mist or smoke channels are arranged in the outer shell and the cigarette holder, one end of each channel is communicated with the air outlet hole on the cigarette holder, and the other end of each channel is communicated with the mist outlet in the ultrasonic atomization device; this ultrasonic atomization device, including interior casing (10), power (12), stock solution portion (stock solution room/or hold chamber) (14), netted component (20) and vibration source (30), be formed with stock solution portion (stock solution room/or hold chamber) (14) in casing (10), stock solution portion (stock solution room/or hold chamber) (14) (middle) separate each other not communicating with each other, and the upper end is equipped with open and close filling opening, and is equipped with the aerial fog export, aerial fog export and communicating fog or smog passageway with it are (middle) keep apart each other not communicating, netted component (20) inlay and locate the aerial fog exit, netted component (20) are the porous network structure who has a plurality of micropores (21), vibration source (30) with netted component (20) are connected, vibration source (30) with power (12) electricity is connected, the vibration source (30) can generate vibration after being electrified and drives the mesh component (20) to vibrate so as to vibrate and atomize the liquid near the mesh component (20); the micro holes (21) penetrate through the mesh-shaped member (20) so that the atomized liquid smoke can flow out along the micro holes (21), the mesh-shaped member (20) is electrically connected with the power supply (12), and the mesh-shaped member (20) can generate heat and atomize the liquid near the mesh-shaped member (20) by heating after being electrified.
26. The apparatus according to claim 25, characterized in that the ultrasonic atomizing device, wherein the vibration source (30) is at least partially located in the reservoir (14), and an end surface of one end of the vibration source (30) is connected to the mesh member (20).
27. The device according to claim 25, characterized in that the ultrasonic atomization device, wherein the vibration source (30) is located between the power source (12) and the reservoir (14) and one end of the vibration source (30) extends into the reservoir (14).
28. The device according to claim 25, characterized in that the ultrasonic atomization device is used for an electronic cigarette, a partition plate (18) hermetically connected with the housing (10) is arranged in the housing (10), the partition plate (18) forms the bottom of the liquid storage part (14) in a sealed manner, and one end of the vibration source (30) upwards penetrates through the partition plate (18) and extends into the liquid storage part (14).
29. The device according to claim 25, characterized in that the ultrasonic atomizing device is characterized in that a cover liner (24) is provided between the peripheral edge of the mesh member (20) and the aerosol outlet of the reservoir (14), the mesh member (20) and the housing (10) are sealed by the cover liner (24), and the peripheral edge of the mesh member (20) abuts against the cover liner (24), so that the mesh member (20) can be held in the cover liner (24) even when vibrated.
30. The device according to claim 25, characterized in that the ultrasonic atomization device, wherein the longitudinal section of the liquid storage part (14) is in a concave shape, two gas mist channels (16) which are isolated from each other (in the middle) are formed in the center of the liquid storage part (liquid storage chamber/or accommodating cavity) (14), one end of the fine hole (21) of the mesh-shaped member (20) is communicated with the liquid storage part (14), and the other end is communicated with the gas mist channel (16).
31. The device according to claim 25, wherein the mesh member (20) is a flat plate structure, the micropores (21) of the mesh member (20) are formed by gaps after the ribs (23) are arranged in a honeycomb shape, the micropores (21) have a large pore diameter at both ends and a small pore diameter at the middle or the micropores (21) have a large pore diameter at one end and a small pore diameter at the other end, wherein when the micropores (21) have a large pore diameter at one end and a small pore diameter at the other end, the end with a large pore diameter is a liquid inlet end communicated with the inside of the liquid storage part (14), and the end with a small pore diameter is an aerosol outlet end.
32. The device according to claim 25, wherein the mesh member (20) further comprises a metal mesh, the metal mesh comprises two layers, namely a top layer metal mesh arranged on the top of the mesh member (20) and a bottom layer metal mesh arranged on the bottom of the mesh member (20), and the ribs (23) are arranged between the bottom layer metal mesh and the top layer metal mesh at intervals and are electrically connected with the bottom layer metal mesh and the top layer metal mesh.
33. The device according to claim 25, characterized in that the ultrasonic atomizing device is characterized in that the material of the mesh-like member (20) is a conductive anticorrosive material.
34. A device (kit) with an oil cup for aerosolization or vaporization or aerosolization of an electronic cigarette (or aerosol-generating system/material), comprising a housing (1) and a control assembly (2), a battery (3) and an atomizer (4) arranged in the housing (1), the control assembly (2) being electrically connected to the battery (3) and a heater (41) of the atomizer (4), respectively, characterized in that: still be equipped with in casing (1) and be used for holding oil cup (stock solution room/or hold chamber) (5) of holding the tobacco juice, atomizer (4) and oil cup (stock solution room/or hold chamber) (5) adjacent arrangement, oil cup (5) are equipped with tobacco juice export (51) by the one end of atomizer (4), material (52) that have the micropore in the tobacco juice export (51) department is packaged with, heater (41) of atomizer (4) hug closely the material (52) that have the micropore in arrange, atomizer (4) and oil cup (stock solution room/or hold chamber) (5) are interior to have two chambeies (stock solution room/or hold the chamber) that separate not communicating mutually, tobacco juice export (51) and communicating mist or smog passageway separate not communicating mutually with it.
35. The device according to claim 34, characterized in that the aperture of the smoke outlet (51) in the electronic cigarette is the same size as the aperture of the oil cup (5).
36. The device according to the technical scheme 34 is characterized in that one end of the shell (1) in the electronic cigarette is provided with (the middle of the shell is provided with) two cigarette holder covers (11) which are not communicated with each other but through which smoke can pass through pore channels respectively and are provided with the pore channel openings (namely, the cigarette holder holes), the other end of the shell (1) is provided with a lamp cover (12) with an LED lamp, the control component (2) is fixed in the lamp cover (12), and the control component (2) comprises a control circuit board and a control switch.
37. The device according to the technical scheme 34 is characterized in that a first air inlet hole (121) is formed in the side face of the lamp cover (12) in the electronic cigarette, and a control switch of the control assembly (2) is an air suction type automatic switch.
38. The device according to the technical scheme 34 is characterized in that the atomizer (4) in the electronic cigarette comprises an oil-separating silica gel seat (42) and a connecting pipe (43) which is isolated from each other and is not communicated with each other (middle) but the smoke can pass through the connecting pipe respectively, the oil-separating silica gel seat (42) is in interference fit with the shell (1), one end of the connecting pipe (43) is abutted against the oil-separating silica gel seat (42), the other end of the connecting pipe (43) is abutted against a material (preferably a non-woven fabric (52)) with micro holes in the end face of the smoke liquid outlet (51), two glass fiber ropes (44) are respectively arranged on two isolated cavities of the connecting pipe (43), the heating wire (41) is wound on the glass fiber ropes (44), two air inlet holes (or middle) isolated from each other (421) are arranged on the oil-separating silica gel seat (42) and are respectively communicated with two isolated cavities of the connecting pipe (43), the air hole (421) is respectively communicated with the first air inlet hole (121) and a suction nozzle hole on the cigarette holder cover (11).
39. A device (kit, device, apparatus) for aerosolization or vaporisation or aerosolization of an electronic cigarette (or aerosol-generating system/material), the device comprising a housing, power supply components, necessary accessories and 2 separate, non-communicating aerosolization subsystems; the lower shell body comprises a power supply component, an atomization subsystem and two isolated and non-communicated fog or smoke channels, wherein one end of each fog or smoke channel is communicated with the atomization subsystem, and the other end of each fog or smoke channel is communicated with the fog or smoke channel in the upper shell body; the upper casing is a cigarette holder, the long bottom is connected with the lower casing, the short bottom is provided with two air outlets, two isolated and non-communicated fog or smoke channels are arranged in the bottom, one end of the bottom is communicated with the air outlets, and the other end is communicated with the fog or smoke channels in the lower casing.
40. The device according to claim 39, wherein the independent atomizing subsystem comprises a liquid storage chamber or a receiving chamber (and components thereof), an atomizing chamber (and components thereof), a mist or smoke channel (and components thereof) or a guide member 1, and an atomizing component, wherein the liquid storage chamber or the receiving chamber is directly communicated with the atomizing chamber or communicated with the atomizing chamber through a guide member 2, the mist or smoke channel or the guide member 1 is a mist or smoke channel in the upper and lower housings, the two liquid storage chambers or the receiving chamber are isolated and not communicated, the two atomizing chambers are isolated and not communicated, the two guide members 2 are isolated and not communicated, and the two mist or smoke channels or the guide member 1 are isolated and not communicated.
41. A device (kit, device, unit) according to claims 1-40, characterized in that the device is used for aerosolizing or vaporizing or aerosolizing two different aerosol-generating materials.
The main characteristics and advantages of the invention (industrial applicability):
1) the throat-soothing tea is gentle and soft in use, good in throat-crossing property and/or oral property, not easy to generate resistance by a user, good in satisfaction and comfort, low in throat-choking feeling and small in irritation;
2) the throat choking feeling of the electronic cigarette (generated by free nicotine) is better reduced, and the comfort level is greatly improved.
Description of the drawings:
1. FIG. 1-1 is a schematic structural view of an example electronic smoking article 4-1;
2. FIGS. 1-2 are schematic views of a magnetostrictive ultrasonic vibrator and an electromagnetic induction heater in an example electronic smoking article 4-1;
3. FIGS. 1-3 are schematic diagrams of control circuits for an example electronic smoking article 4-1;
4. FIGS. 1-4 are schematic views of a pneumatic switch of an example electronic smoking article 4-1;
5. FIGS. 1-5 are schematic diagrams of the subject circuit board structure of example electronic smoking article 4-1;
6. fig. 1-6 are schematic views of the structure of a cartridge of an example of an electronic smoking article 4-1.
7. FIG. 2-1 is a schematic structural view of an ultrasonic atomizing device of example electronic smoking article 4-2;
8. fig. 2-2 is a flow chart of the operation of the ultrasonic atomization device of the electronic smoking set example 4-2.
9. Fig. 3-1 is a schematic cross-sectional structure diagram of an example electronic smoking article 4-3.
Examples
Example 1
Nicotine salt solution: maleic acid nicotine salt, concentration: 0.08%, solvent: water and butanediol (volume ratio 9: 1), pH: 5.2 (to) Total amount: 100 ml;
alkali solution: potassium leucine, concentration: 12.5%, solvent: water, (added) total amount: 100 ml.
An atomization device: the mist outlet of one independent ultrasonic atomizer is connected with the mist outlet of the other independent ultrasonic atomizer by two independent non-communicated guide tubes respectively, the other end of each guide tube is connected with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch tube at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer is Yuehua ultrasonic atomizer (model: WH-2000), and the atomization speed is about 2 ml/min.
Example 2
Nicotine salt solution: galactaric acid nicotine salt, concentration: 1.5%, solvent: water and ethanol (volume ratio 8: 2), pH: 3.2 (to) total amount: 100 ml;
alkali solution: fucosamine, concentration: 4.5%, solvent: water and glycerol (volume ratio 8: 2), (added to) total: 100 ml.
An atomization device: the mist outlet of one independent compression atomizer is connected with the mist outlet of the other independent compression atomizer by two independent non-communicated guide tubes respectively, the other end of each guide tube is connected with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch tube at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer comprises: the atomization speed of the fish jump compression type atomizer (model: 403H) is about 0.25 ml/min.
Example 3
Nicotine salt solution: malic acid nicotine salt, concentration: 0.5%, solvent: water and propylene glycol (volume ratio 7: 3), pH: 5.6 (to) Total amount: 100 ml;
alkali solution: ornithine sodium, concentration: 17.5%, solvent: water, (added) total amount: 100 ml.
An atomization device: the mist outlet of one independent compression atomizer is connected with the mist outlet of the other independent compression atomizer by two independent non-communicated guide tubes respectively, the other end of each guide tube is connected with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch tube at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer comprises: an ohm-dragon compression atomizer (model: NE-C25S), the atomization speed is about 0.25 ml/min.
Example 4
Nicotine salt solution: nicotinic acid nicotine salt, concentration: 0.7%, solvent: water and glycerol (volume ratio 7.5: 2.5), pH: 6.2 (add) to total amount: 100 ml;
alkali solution: sodium propionate, concentration: 1.5%, solvent: water and propylene glycol (6: 4 by volume), (add to) total: 100 ml.
An atomization device: the mist outlet of one independent compression atomizer is connected with the mist outlet of the other independent compression atomizer by two independent non-communicated guide tubes respectively, the other end of each guide tube is connected with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch tube at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer comprises: an ohm-dragon compression type atomizer (model: NE-C28), the atomization speed is about 0.25 ml/min.
Example 5
Nicotine salt solution: nicotine succinate (succinate), concentration: 3.5%, solvent: water and glycerol acetate (volume ratio 9: 1), pH: 5.2 (to) Total amount: 100 ml;
alkali solution: calcium gluconate, concentration: 0.5%, solvent: water and glycerol (volume ratio 7: 3), (added to) total: 100 ml.
An atomization device: the mist outlet of one independent net type atomizer is connected with the mist outlet of the other independent net type atomizer by two independent non-communicated guide pipes respectively, the other end of each guide pipe is connected with two branch pipes in a tee joint, the branch pipe at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch pipe at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer is a fish-jumping-net type atomizer (model: M-102 or HL100A), and the atomization speed is about 0.2 ml/min.
Example 6
Nicotine salt solution: ketoglutarate nicotine salt, concentration: 4.5%, solvent: water and polyethylene glycol (volume ratio 8.5: 1.5), pH: 4.5 (to) Total amount: 100 ml;
alkali solution: sodium pyrophosphate, concentration: 1.5%, solvent: water and butanediol (volume ratio 9.5: 0.5), (added) to the total: 100 ml.
An atomization device: the mist outlet of one independent compression atomizer is connected with the mist outlet of the other independent compression atomizer by two independent non-communicated guide tubes respectively, the other end of each guide tube is connected with two branch tubes in a tee joint, the branch tube at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch tube at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer is a Philips compression atomizer (model: CN-B-0103), and the atomization speed is about 0.2 ml/min.
Example 7
Nicotine salt solution: nicotine citrate salt, concentration: 1.5%, solvent: water and triacetin (volume ratio 8.5: 1.5), pH: 5.3 (to) Total amount: 10 ml;
alkali solution: sodium hydrogen phosphate, concentration: 0.8%, solvent: water and propylene glycol (volume ratio 8.5: 1.5), (added to) total: 1000 ml.
An atomization device: the mist outlet of one independent net type atomizer is connected with the mist outlet of the other independent net type atomizer by two independent non-communicated guide pipes respectively, the other end of each guide pipe is connected with two branch pipes in a tee joint, the branch pipe at the other end of the tee joint is communicated with an inhalation mask capable of covering the nose and the mouth, a user can inhale mist or smoke in the inhalation mask through the inhalation mask by using the nasal cavity or/and the oral cavity, and the tee joint is spaced from and not communicated with the branch pipe at one end communicated with the inhalation mask capable of covering the nose and the mouth. The ultrasonic atomizer is a Leifushi net type atomizer (model: mini air 360+), and the atomization speed is about 0.8 ml/min.
Example 8
Nicotine salt solution: tartrate nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, polydiglycerol (volume ratio 1.5: 6.5: 2), pH: 6.5 (to) Total amount: 100 ml;
alkali solution: sodium carbonate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is a smoking set disclosed in patent CN201410223508.8 or a commercially available electronic smoking set (such as a magic flute MOTI brand, a TENSO brand, a chinese salmo brand, a HOPESON brand, and the same is applied below).
Example 9
Nicotine salt solution: nicotine acetate, concentration: 2.5%, solvent: water and propylene carbonate (volume ratio 1.5: 8.5), pH: 5.5 (to) Total amount: 100 ml;
alkali solution: sodium phosphate, concentration: 1.2%, solvent: water and propyl glyceryl diacetate (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN201410371441.2 or a commercially available electronic smoking set.
Example 10
Nicotine salt solution: butyrate nicotine salt, concentration: 0.5%, solvent: water, propylene glycol, triacetin (volume ratio 1.5: 6.5: 2), pH: 5.2 (to) Total amount: 1000 ml;
alkali solution: trisodium glycyrrhizinate, concentration: 0.5%, solvent: water and propylene glycol, glycerol (volume ratio 1: 7.5: 1.5), (added to) total amount: 10 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201320043282.4 or the commercially available electronic smoking set.
Example 11
Nicotine salt solution: lactate nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, polyglycerol (volume ratio 1: 7: 2), pH: 4.2 (to) Total amount: 100 ml;
alkali solution: sodium saccharin, concentration: 2.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000190.6 or the commercially available electronic smoking set.
Example 12
Nicotine salt solution: nicotine acrylate salt, concentration: 1.5%, solvent: water and propylene carbonate (volume ratio 1.5: 8.5), pH: 6.5 (to) Total amount: 100 ml;
alkali solution: potassium sulfopropionate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000289.6 or the commercially available electronic smoking set.
Example 13
Nicotine salt solution: gluconic acid nicotine salt, concentration: 1.5%, solvent: water, propylene glycol and polyethylene glycol 200 (volume ratio 1: 8: 1), pH value: 5.3 (to) Total amount: 10 ml;
alkali solution: ammonium valine, concentration: 3.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201320734533.3 or the commercially available electronic smoking set.
Example 14
Nicotine salt solution: l-lactic acid nicotine salt, concentration: 0.5%, solvent: water and propylene carbonate (volume ratio 1.5: 8.5), pH: 4.2 (to) Total amount: 100 ml;
alkali solution: arginine, concentration: 4.5%, solvent: water and propylene glycol, glyceryl caprylate (volume ratio 1.5: 6.5: 2), (add to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201320734377.0 or the commercially available electronic smoking set.
Example 15
Nicotine salt solution: a-hydroxyhexanoate nicotine salt, concentration: 1.5%, solvent: water, propylene glycol, glycerin (volume ratio 1.5: 7.5: 1), pH: 5.2 (to) Total amount: 100 ml;
alkali solution: triethanolamine, concentration: 1.5%, solvent: propylene glycol, (add to) total amount: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000294.7 or the commercially available electronic smoking set.
Example 16
Nicotine salt solution: caprylic acid nicotine salt, concentration: 4.5%, solvent: water, propylene glycol, polyhexaglycerol (volume ratio 1.5: 7.5: 1), pH: 5.6 (to) Total amount: 100 ml;
alkali solution: sodium glycinate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000291.3 or the commercially available electronic smoking set.
Example 17
Nicotine salt solution: benzoic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 200 ml;
alkali solution: lysine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN201410371441.2 or a commercially available electronic smoking set.
Example 18
Nicotine salt solution: salicylic acid nicotine salt, concentration: 0.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), pH: 6.4 (to) Total amount: 100 ml;
alkali solution: thiamine, concentration: 0.5%, solvent: water and propylene glycol, glycerol acetate (volume ratio 1.5: 6.5: 2), (add to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN200710121524.6 or a commercially available electronic smoking set.
Example 19
Nicotine salt solution: mandelic acid (mandelic acid) nicotine salt, concentration: 3.5%, solvent: water, propylene glycol, polyethylene glycol 300 (volume ratio 1.5: 7.5: 1), pH: 5.5 (to) Total amount: 100 ml;
alkali solution: sodium phenylalanine, concentration: 1.5%, solvent: water and propylene glycol, glycerol (volume ratio 1.5: 6.5: 2), (add to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201621239037.0 or the commercially available electronic smoking set.
Example 20
Nicotine salt solution: protocatechuic acid (3, 4-dihydroxybenzoic acid) nicotine salt, concentration: 6.5%, solvent: water, propylene glycol, diethyl malate (volume ratio 1.5: 8.0: 0.5), pH: 5.2 (to) Total amount: 100 ml;
alkali solution: pyridoxamine, concentration: 2.5%, solvent: water and propylene glycol, caproate glyceride (volume ratio 1.5: 8.0: 0.5), (add to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is a smoking set disclosed in the utility model patent CN201720429415.X or a commercially available electronic smoking set.
Example 21
Nicotine salt solution: glucuronic acid nicotine salt, concentration: 5.5%, solvent: water, propylene glycol, diethyl succinate (volume ratio 1.5: 8.0: 0.5), pH: 4.5 (to) Total amount: 100 ml;
alkali solution: neamine, concentration: 2.5%, solvent: water and propylene glycol, glycerol (volume ratio 1.5: 6.5: 2), (add to) total: 100 ml.
An atomization device: the apparatus of example 4-1 (i.e., the apparatus shown in FIGS. 1-6) is described.
Example 22
Nicotine salt solution: ascorbate nicotine salt, concentration: 9.5%, solvent: water and propylene carbonate (volume ratio 1.5: 8.5), pH: 5.4 (to) Total amount: 100 ml;
alkali solution: pyridoxine, concentration: 2.5%, solvent: ethanol and propylene glycol (1: 9 by volume), (added to) total: 100 ml.
An atomization device: the apparatus of example 4-1 (i.e., the apparatus shown in FIGS. 1-6) is described.
Example 23
Nicotine salt solution: angelic acid ((Z) -2-methyl-2-butenoic acid) nicotine salt, concentration: 3.5%, solvent: water, propylene glycol and propylene carbonate (volume ratio is 1.5: 6.5: 2), pH value: 6.5 (to) Total amount: 100 ml;
alkali solution: meglumine, concentration: 1%, solvent: water and triacetin (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the apparatus of example 4-1 (i.e., the apparatus shown in FIGS. 1-6) is described.
Example 24
Nicotine salt solution: carboxyglutamic acid nicotine salt, concentration: 4.5%, solvent: water and propylene glycol (volume ratio 2: 8), pH: 6.2 (add) to total amount: 100 ml;
alkali solution: galactosamine, concentration: 2.5%, solvent: water and propylene glycol, glycerol (volume ratio 1.5: 7.5: 1), (added to) total: 100 ml.
An atomization device: the apparatus of example 4-1 (i.e., the apparatus shown in FIGS. 1-6) is described.
Example 25
Nicotine salt solution: glycyrrhizic acid nicotine salt, concentration: 3.5%, solvent: water, propylene glycol, glyceryl caprylate (volume ratio 1.5: 7.5: 1), pH: 6.1 (to) Total amount: 100 ml;
alkali solution: caffeine, concentration: 0.5%, solvent: ethanol and propylene glycol (volume ratio 0.5: 9.5), (added to) total: 100 ml.
An atomization device: the device in the specification is an example 4-2 (i.e., the device shown in FIGS. 2-1-2).
Example 26
Nicotine salt solution: aspartate nicotine salt, concentration: 3.5%, solvent: water, propylene glycol, triacetin (volume ratio 1.5: 6.5: 2), pH: 5.7 (to) Total amount: 100 ml;
alkali solution: 2-desosamine, concentration: 4.5%, solvent: water and propylene glycol, glycerol (volume ratio 1.5: 7.0: 1.5), (added to) total: 100 ml.
An atomization device: example 4-3 of the apparatus (i.e., the apparatus shown in FIG. 3-1) is set forth in the specification.
Example 27
Nicotine salt solution: inosinic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, glyceryl caprylate (volume ratio 1.5: 7.5: 1), pH: 6.2 (add) to total amount: 100 ml;
alkali solution: tributanolamine, concentration: 0.8%, solvent: propylene glycol, (add to) total amount: 100 ml.
An atomization device: example 4-3 of the apparatus (i.e., the apparatus shown in FIG. 3-1) is set forth in the specification.
Example 28
Nicotine salt solution: cinnamic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol and propylene carbonate (volume ratio is 1.5: 6.5: 2), pH value: 5.2 (to) Total amount: 100 ml;
alkali solution: glucosamine, concentration: 0.5%, solvent: water and poloxamer 124, (add to) total amount: 100 ml.
An atomization device: example 4-3 of the apparatus (i.e., the apparatus shown in FIG. 3-1) is set forth in the specification.
Example 29
Nicotine salt solution: nicotine hydrochloride salt, concentration: 2.5%, solvent: water, propylene glycol, glyceryl tripropionate (volume ratio 1.5: 7.5: 1), pH: 4.8, (add) total amount: 100 ml;
alkali solution: N-acetyl-D-glucosamine, concentration: 1.0%, solvent: benzyl benzoate and ethanol (volume ratio 8.5: 1.5), (added to) total: 100 ml.
An atomization device: example 4-3 of the apparatus (i.e., the apparatus shown in FIG. 3-1) is set forth in the specification.
Example 30
Nicotine salt solution: nicotine sulfate salt, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), pH: 4.2 (to) Total amount: 100 ml; propylene glycol
Alkali solution: dipropanolamine, concentration: 0.5%, solvent: dodecenyl acetate and ethanol (volume ratio 8.5: 1.5), (added to) total amount: 100 ml.
An atomization device: the device in the specification is 4-4, the lower shell and the upper shell are arranged according to the device in the specification 4-4, and the device which is the same as the device in the specification and comprises the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the utility model CN206079032U or CN201420045870.6 is arranged in the device, and the two sets of the same, independent and non-communicated devices are arranged in the device, wherein the devices comprise the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the patent; or example 4-1 of the apparatus in the specification (i.e., the apparatus shown in FIGS. 1-1 to 6).
Example 31
Nicotine salt mixture: nicotine phosphate salt, content: 1.5%, diluent or aerosol generating agent: camphor, (add) total amount: 100g of the total weight of the mixture;
alkali solution: ethanolamine, concentration: 0.5%, solvent: ethyl vanillate and ethanol (volume ratio 8.5: 1.5), (added to) total amount: 100 ml.
An atomization device: the device in the specification is an example 4-2 (i.e., the device shown in FIGS. 2-1-2).
Example 32
Nicotine salt solution: benzenesulfonic acid nicotine salt, concentration: 4.5%, solvent: water, propylene glycol and propylene carbonate (volume ratio is 1.5: 6.5: 2), pH value: 5.6 (to) Total amount: 100 ml;
alkali solution: tromethamine, concentration: 2.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the device in the specification is 4-4, the lower shell and the upper shell are arranged according to the device in the specification 4-4, and the device which is the same as the device in the specification and comprises the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the utility model CN206079032U or CN201420045870.6 is arranged in the device, and the two sets of the same, independent and non-communicated devices are arranged in the device, wherein the devices comprise the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the patent; or example 4-1 of the apparatus in the specification (i.e., the apparatus shown in FIGS. 1-1 to 6).
Example 33
Nicotine salt mixture: pyrosulfite nicotine salt content: 2.5%, diluent or aerosol generating agent: vanillic acid, (add to) total amount: 100g of the total weight of the mixture;
alkali solution: diethanolamine, concentration: 0.8%, solvent: triethyl citrate, (add) total amount: 100 ml.
An atomization device: the device in the specification 4-4, the lower and upper shells of which are arranged according to the device in the specification 4-4, the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the invention patents CN206079032U or CN200910080147.5, and two sets of devices which are identical but not communicated with each other and comprise the components of the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the above patents (which are identical to the patents) are arranged in the device; or example 4-1 of the apparatus in the specification (i.e., the apparatus shown in FIGS. 1-1 to 6).
Example 34
Nicotine salt solution: malic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: sodium glutamate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN201410371441.2 or a commercially available electronic smoking set.
Example 35
Nicotine salt solution: glycyrrhizic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: glufosinate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 36
Nicotine salt solution: tartrate nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: dihydrochalcone sodium, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 37
Nicotine salt solution: gluconic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: trisodium glycyrrhizinate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 38
Nicotine salt solution: nicotinic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: meglumine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 39
Nicotine salt solution: galactaric acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: sodium saccharin, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 40
Nicotine salt solution: glucaric acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: pyridoxine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
EXAMPLE 41
Nicotine salt solution: glutamate nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: thiamine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 42
Nicotine salt solution: aspartate nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: pyridoxamine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 43
Nicotine salt solution: benzoic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: arginine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 44
Nicotine salt solution: ascorbate nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: lysine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 45
Nicotine salt solution: dehydroascorbic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: sodium methionine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 46
Nicotine salt solution: erythorbic acid nicotine salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: sodium glycinate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 47 (comparative example 34)
Nicotine salt solution: nicotine hydrochloride salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: ethanolamine, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 48 (comparative example 35)
Nicotine salt solution: nicotine citrate salt, concentration: 2.5%, solvent: water, propylene glycol, poly (dipropylene glycol) (volume ratio 1.5: 7.5: 1), pH: 5.0, (add) total amount: 100 ml;
alkali solution: sodium hydrogen phosphate, concentration: 1.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), (added to) total: 100 ml.
An atomization device: the same as in example 34.
Example 49
Nicotine salt mixture: isovaleric acid nicotine salt, content: 1.5%, diluent or aerosol generating agent: sorbitol, (add) total amount: 100g of the total weight of the mixture;
alkali solution: triethanolamine, concentration: 1.5%, solvent: propylene glycol, (add to) total amount: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000294.7 or the commercially available electronic smoking set.
Example 50
Nicotine salt mixture: nicotine salt of 2-methylbutyric acid, content: 3.5%, diluent or aerosol generating agent: 1, 3-dihydroxyacetone, (to) total amount: 100g of the total weight of the mixture;
alkali mixture: urea, content: 1.5%, diluent or aerosol generating agent: sorbitol, (add) total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000291.3 or the commercially available electronic smoking set.
Example 51
Nicotine salt mixture: nicotine benzoate, content: 2.5%, diluent or aerosol generating agent: erythrose, (add to) total amount: 100g of the total weight of the mixture;
alkali mixture: glutamine, content: 1.0%, diluent or aerosol generating agent: xylitol, (add to) total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN201410371441.2 or a commercially available electronic smoking set.
Example 52
Nicotine salt solution: phenylacetic acid nicotine salt, concentration: 0.5%, solvent: water and propylene glycol (volume ratio 1.5: 8.5), pH: 6.4 (to) Total amount: 100 ml;
alkali mixture: thiamine, content: 2.0%, diluent or aerosol generating agent: erythritol, (add to) total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN200710121524.6 or a commercially available electronic smoking set.
Example 53
Nicotine salt mixture: isohexide nicotine salt, content: 2.0%, diluent or aerosol generating agent: fructose, (add) total amount: 100g of the total weight of the mixture;
alkali mixture: unano, content: 1.0%, diluent or aerosol generating agent: menthol, (add to) total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201621239037.0 or the commercially available electronic smoking set.
Example 54
Nicotine salt mixture: butyrate nicotine salt content: 4.5%, diluent or aerosol generating agent: lactic acid, (added) total amount: 100g of the total weight of the mixture;
alkali mixture: arginine, content: 85%, diluent or aerosol generating agent: menthol, (add to) total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is a smoking set disclosed in the utility model patent CN201720429415.X or a commercially available electronic smoking set.
Example 55
Nicotine salt mixture: propionate nicotine salt, content: 2.0%, diluent or aerosol generating agent: lauric acid, (add to) total amount: 100g of the total weight of the mixture;
alkali solution: tripentanolamine, concentration: 2.5%, solvent: water and propylene glycol, glycerol (volume ratio 1.5: 6.5: 2), (add to) total: 100 ml.
An atomization device: the apparatus of example 4-1 (i.e., the apparatus shown in FIGS. 1-6) is described.
Example 56
Nicotine salt mixture: nicotine acetate, content: 2.5%, diluent or aerosol generating agent: xylose, (added) total amount: 100g of the total weight of the mixture;
alkali mixture: ammonium glycinate, content: 75%, diluent or aerosol generating agent: coronenol (added) in the total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is a smoking set disclosed in the utility model patent CN201720429415.X or a commercially available electronic smoking set.
Example 57
Nicotine salt solution: benzoic acid nicotine salt, concentration: 3.5%, solvent: water, triethylene glycol, propylene carbonate (volume ratio is 1.5: 6.5: 2), pH value: 6.5 (to) Total amount: 100 ml;
alkali solution: meglumine, concentration: 1%, solvent: water and tetraethylene glycol (volume ratio 3: 7), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201621239037.0 or the commercially available electronic smoking set.
Example 58
Nicotine salt solution: carboxyglutamic acid nicotine salt, concentration: 1.5%, solvent: water and ethyl lactate (volume ratio 2: 8), pH: 6.2 (add) to total amount: 100 ml;
alkali solution: lysine, concentration: 2.5%, solvent: water and propylene glycol, glycerol (volume ratio 1.5: 7.5: 1), (added to) total: 100 ml.
An atomization device: the device in the specification is an example 4-2 (i.e., the device shown in FIGS. 2-1-2).
Example 59
Nicotine salt solution: glycyrrhizic acid nicotine salt, concentration: 0.5%, solvent: water, propylene glycol, triacetin (volume ratio 1.5: 6.5: 2), pH: 6.1 (to) Total amount: 100 ml;
alkali solution: tromethamine, concentration: 0.5%, solvent: ethanol and ethyl myristate (volume ratio 0.5: 9.5), (added to) total: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is disclosed in patent CN200710121524.6 or a commercially available electronic smoking set.
Example 60
Nicotine salt mixture: glycyrrhizic acid nicotine salt, content: 1.0%, diluent or aerosol generating agent: ethyl vanillin, (add to) total amount: 100g of the total weight of the mixture;
alkali solution: diethanolamine, concentration: 0.5%, solvent: ethanol and dimethyl dodecanedioate (volume ratio 0.5: 9.5), (added) to the total amount: 100 ml.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201621239037.0 or the commercially available electronic smoking set.
Example 61
Nicotine salt mixture: nicotine salt of 2-methylbutyric acid, content: 75%, diluent or aerosol generating agent: phenylacetic acid, (add) total amount: 100g of the total weight of the mixture;
alkali mixture: urea, content: 1.0%, diluent or aerosol generating agent: arabinose, (add to) total amount: 100 g.
An atomization device: two identical independent electronic smoking sets are respectively connected by two independent non-communicated conduits (such as rubber tubes and silicone tubes) with two ends of different sizes and are used for oral inhalation after combination, the larger end of the conduit is communicated with the smoking set mist outlet, the smaller end of the conduit is used for oral inhalation, and the outer diameter of the smaller end of the conduit is 3mm-4 mm. The electronic smoking set is the smoking set disclosed in the utility model patent CN201390000291.3 or the commercially available electronic smoking set.
Example 62
Nicotine salt solution: nicotine isopropyl acid salt, concentration: 1.5%, solvent: 2, 2-dimethyl-1, 3-dioxolane-4-methanol, (added) to the total amount: 100 ml;
alkali solution: triethanolamine, concentration: 1.5%, solvent: 1, 3-propanediol lactylate, (added to) total amount: 100 ml.
An atomization device:
example 62-1: the apparatus of example 4-1 (i.e., the apparatus shown in FIGS. 1-6) is described.
Example 62-2: the other parts are not changed, and only the other ends of the two mist or smog channels or the guide parts 1 in the atomizing device in the embodiment are respectively communicated with the suction (nozzle) holes, but the other ends are communicated with the suction (nozzle) holes together, namely the two suction (nozzle) holes are changed into the suction (nozzle) holes.
Example 63
Nicotine salt solution: l-gulonic acid nicotine salt, concentration: 1.5%, solvent: glycofurol, (add) to the total amount: 100 ml;
alkali solution: chitobiose, concentration: 1.5%, solvent: water and 1, 3-dioxolane-4-methanol (volume ratio 0.5: 9.5), (added to) total amount: 100 ml.
An atomization device:
example 63-1: the device in the specification is an example 4-2 (i.e., the device shown in FIGS. 2-1-2).
Example 63-2: the other parts are not changed, and only the other ends of the two mist or smog channels or the guide parts 1 in the atomizing device in the embodiment are respectively communicated with the suction (nozzle) holes, but the other ends are communicated with the suction (nozzle) holes together, namely the two suction (nozzle) holes are changed into the suction (nozzle) holes.
Example 64
Nicotine salt solution: d-nicotine lactate salt, concentration: 1.5%, solvent: 1, 3-dioxan-5-ol, (added) to total amount: 100 ml;
alkali solution: triisopropanolamine, concentration: 1.5%, solvent: 1, 3-propanediol monoethyl ester, (add to) total amount: 100 ml.
An atomization device:
example 64-1: example 4-3 of the apparatus (i.e., the apparatus shown in FIG. 3-1) is set forth in the specification.
Example 64-2: the other parts are not changed, and only the other ends of the two mist or smog channels or the guide parts 1 in the atomizing device in the embodiment are respectively communicated with the suction (nozzle) holes, but the other ends are communicated with the suction (nozzle) holes together, namely the two suction (nozzle) holes are changed into the suction (nozzle) holes.
Example 65
Nicotine salt solution: glucoheptonate nicotine salt, concentration: 1.5%, solvent: water and 1, 3-dioxane-5-ol (volume ratio 1: 9), pH: 5.2 (to) Total amount: 100 ml;
alkali solution: dipentanolamine, concentration: 1.5%, solvent: 1, 3-propylene glycol monopropyl ester, (added to) total amount: 100 ml.
An atomization device:
example 65-1: the device in the specification 4-4, the lower and upper shells of which are arranged according to the device in the specification 4-4, the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the invention patents CN206079032U or CN200910080147.5, and two sets of devices which are identical but not communicated with each other and comprise the components of the power supply assembly, the atomizing subsystem, the accessories and the like disclosed in the above patents (which are identical to the patents) are arranged in the device; or example 4-1 of the apparatus in the specification (i.e., the apparatus shown in FIGS. 1-1 to 6).
Example 65-2: the other parts are not changed, and only the other ends of the two mist or smog channels or the guide parts 1 in the atomizing device in the embodiment are respectively communicated with the suction (nozzle) holes, but the other ends are communicated with the suction (nozzle) holes together, namely the two suction (nozzle) holes are changed into the suction (nozzle) holes.
The preparation method of the nicotine salt in the above examples adopts a method known in the art or directly adopts a method in which a nicotine salt, such as CN1607950A, CN101222915A, cn201480025499.x, CN201580038462.5, CN201180028544.3, CN201680079884.1, CN201180022735.9, CN03812809.8, etc.;
the preparation method of the nicotine salt can also adopt the following simple method:
mixing excessive nicotine (free nicotine) with acid (pKa value lower than that of nicotine) in the amount of 1.2, which is not over 1.5 for saving, spray drying (normal temperature to 120 deg.c) or freeze spray drying to eliminate water and excessive volatile free nicotine to obtain nicotine salt.
Description of the drawings: 1) the pH adjusting agents of the above examples are (0.1mol/l) acid or hydrochloric acid, each salified with nicotine, or sodium hydroxide solution;
2) the solution and the mixture are uniformly mixed;
3) the nicotine salt solution/mixture and the alkaline solution/mixture are respectively placed in two separated and non-communicated liquid storage chambers (parts)/containing cavities (or containing cavities) in the atomization device, or the compositions (I) and (II) are respectively preset in containers of glass, ceramics, metal and the like and then are placed in the two separated and non-communicated liquid storage chambers/containing cavities (or containing cavities) together with the containers.
Comparative examples 1 to 33-1, 49 to 61-1
The reference was prepared as follows:
respectively and uniformly mixing the same amount of nicotine salt solution or nicotine salt mixture (such as 10ml or 10g) and alkali solution or alkali mixture (such as 10ml or 10g) in the corresponding embodiment to obtain the control in the control example (for example, respectively and uniformly mixing 10ml of nicotine salt solution (or 10g of nicotine salt mixture) and 10ml of alkali solution (or 10g of alkali mixture) in the corresponding embodiment to obtain the control in each control example), and replacing the nicotine salt solution and alkali solution/or alkali mixture in the corresponding embodiment with the mixed control.
An atomization device: as in its corresponding embodiment.
Comparative examples 1 to 33-2, 49 to 61-2
Comparison products:
1) nicotine salt solution, or nicotine salt mixture: the nicotine salt solution or nicotine salt mixture in its corresponding example, i.e. as in its corresponding example, is unchanged; and
2) the alkali solution and/or alkali mixture in the corresponding examples was replaced by a neutralized alkali solution or a neutralized alkali mixture, and the preparation was carried out as follows:
neutralized base solution: taking the same amount of corresponding alkali in each corresponding embodiment, adding about 85% of the total amount of corresponding solvent, uniformly mixing, adjusting the pH value to 6.9-7.1 by (0.1mol/l) hydrochloric acid or sodium hydroxide solution, and adding the rest amount of corresponding solvent to the total amount (namely 100 ml); or
Neutralized base mixture: the hydrochloride of the corresponding base in each corresponding example (i.e. which has been neutralized with hydrochloric acid) is taken, an amount of the corresponding diluent or aerosol generating agent of the corresponding example is added to make the equivalent content of the base to be the same as that in the corresponding example (the amount of the base is the same as that in the corresponding example based on the free base), and the mixture is mixed.
The nicotine salt solution 1) and the neutralized alkali solution/or alkali mixture 2) are not mixed together, and the corresponding nicotine salt solution and alkali solution/alkali mixture in the corresponding embodiments are replaced respectively.
An atomization device: as in its corresponding embodiment.
Comparative examples 1 to 33-3, 49 to 61-3
Comparison products:
1) alkaline nicotine salt solution: the formulation and the preparation method are substantially the same as those of the nicotine salt solution in the corresponding examples (the same as those of the corresponding examples, the production date is 2 months), and only different from the above, the pH value is adjusted to 7.2-9.5 by using the original acid for forming the nicotine salt or the alkali in the alkali solution in the corresponding examples (wherein, the pH value is 1-3 in the comparative examples: 7.2-7.5; the pH value is 4-10 in the comparative examples: 7.6-8.0; the pH value is 11-20: 8.1-8.5; the pH value is 21-33: 8.6-8.9; the pH value is 49-61: 9.0-9.5; if the alkali mixture is not treated); and
2) blank solvent without base or acid: the alkali in the alkali solution in the corresponding embodiment is removed, and the other parts are unchanged, namely only the corresponding blank solvent is used.
The alkaline nicotine salt solution 1) and the blank solvent 2) without alkali or acid are not mixed together, and the corresponding nicotine salt solution and alkali solution/or alkali mixture in the corresponding embodiments are replaced respectively.
An atomization device: as in its corresponding embodiment.
Comparative examples 1 to 33-4, 49 to 61-4
Comparison products:
1) nicotine salt solution, or nicotine salt mixture: the nicotine salt solution or nicotine salt mixture in its corresponding example, i.e. as in its corresponding example, is unchanged; and
2) blank solvent without base or acid: the alkali in the alkali solution in the corresponding embodiment is removed, and the other parts are unchanged, namely only the corresponding blank solvent is used.
The nicotine salt solution or nicotine salt mixture 1) and the blank solvent 2) without alkali or acid are not mixed together, and the corresponding nicotine salt solution and alkali solution/or alkali mixture in the corresponding embodiments are replaced respectively.
An atomization device: as in its corresponding embodiment.
The application method comprises the following steps:
examples 1 to 33, 49 to 65
The two reservoirs/cavities in the device corresponding to each embodiment are filled with the nicotine salt solution (or nicotine salt mixture) and the alkali solution (or alkali mixture) respectively, wherein the nicotine salt solution (or nicotine salt mixture) contains 2-20mg (calculated as free nicotine) (i.e. the single nicotine dose is 2-20mg (calculated as free nicotine)), and the volumes (or weights) of the alkali solution (or alkali mixture) and the nicotine salt solution (or nicotine salt mixture) are the same. Then the nicotine salt solution (or nicotine salt mixture) and the alkali solution (or alkali mixture) are atomized, the user inhales the aerosol once every 6 seconds, and the two aerosols are breathed into the deep lung (meeting) and then exhaled or spit out until the atomization of the solution (or mixture) is finished.
Examples 34 to 48
The two liquid storage chambers/liquid accommodating chambers in the device corresponding to each embodiment are respectively filled with the nicotine salt solution and the alkali solution in the embodiment, and the volume numbers of the nicotine salt solution and the nicotine salt solution are both 0.50 ml. Then the nicotine salt solution and the alkali solution are atomized, a user inhales the aerial fog from the oral cavity (or/and the nasal cavity) once every 6 seconds, the aerial fog passes through the throat and is swallowed to the lung, and the two kinds of aerial fog are inhaled into the deep part of the lung (meet) and then are exhaled from the nasal cavity until the atomization of the solution is finished.
Comparative examples 1 to 33-1, 49 to 61-1
The two reservoirs/chambers in each control example correspond to the control in the apparatus of the embodiment (same as the apparatus of the corresponding embodiment), and the volume (or weight) of the control in the two reservoirs/chambers is the same as the volume (or weight) of the solution in the corresponding embodiment. Then the solution (or mixture) is atomized, the user inhales the aerosol from the oral cavity (or/and nasal cavity) once every 6 seconds, the aerosol is swallowed to the lung through the throat, and the two kinds of aerosol are inhaled deep in the lung (meet) and then exhaled from the nasal cavity until the atomization of the solution (or mixture) is finished. The atomization rate was the same as in its corresponding example.
Comparative examples 1 to 33-2, 49 to 61-2
The two reservoirs/cavities in each control example correspond to the control 1 in the control example, i.e., the nicotine salt solution (or nicotine salt mixture) in the corresponding example, and the control 2, i.e., the neutralized alkali solution (or neutralized alkali mixture) in the control example, and the volumes of the nicotine salt solution (or nicotine salt mixture) and the neutralized alkali solution (or the weight of the neutralized alkali mixture) are the same and the volume of the solution (or the weight of the mixture) in the corresponding example is the same. Then the nicotine salt solution (or nicotine salt mixture) and the neutralized alkali solution (or neutralized alkali mixture) are atomized, the user inhales the aerosol once every 6 seconds from the oral cavity (or/and nasal cavity), and the aerosol is swallowed to the lung through the throat, and the two aerosols are inhaled to the deep part of the lung (meeting) and then exhaled from the nasal cavity until the atomization of the solution (or mixture) is finished. The atomization rate was the same as in its corresponding example.
Comparative examples 1 to 33-3, 49 to 61-3
The two reservoirs/chambers in each control example corresponding to the device in its embodiment (same as the device in its corresponding embodiment) were filled with the control 1 in the control example: alkaline nicotine salt solution and control 2): the volume of the control 1) and 2) solutions was the same as the volume of the solutions injected for the corresponding examples without the base or acid in the blank solvent. Then atomizing the comparison product 1) and the comparison product 2), wherein the aerosol is inhaled by a user from the oral cavity (or/and the nasal cavity) once every 6 seconds, and is swallowed to the lung through the throat, and the two aerosols are exhaled from the nasal cavity after being inhaled to the deep part of the lung (meeting) until the atomization of the solution (or the mixture) is finished. The atomization rate was the same as in its corresponding example.
Comparative examples 1 to 33-4, 49 to 61-4
The two reservoirs/chambers in each control example corresponding to the device in its embodiment (same as the device in its corresponding embodiment) were filled with the control 1 in the control example: nicotine salt solution, or nicotine salt mixture and control 2): the volume of the control 1) and 2) solutions was the same as the volume of the solutions injected for the corresponding examples without the base or acid in the blank solvent. Then atomizing the comparison product 1) and the comparison product 2), wherein the aerosol is inhaled by a user from the oral cavity (or/and the nasal cavity) once every 6 seconds, and is swallowed to the lung through the throat, and the two aerosols are exhaled from the nasal cavity after being inhaled to the deep part of the lung (meeting) until the atomization of the solution (or the mixture) is finished. The atomization rate was the same as in its corresponding example.
Test example 1 nicotine assay test
Nicotine intake is given in the examples and the control examples described above. Analysis of nicotine effects can be accomplished according to standard methods known in the art, e.g., using a bioassay for determining nicotine in the plasma of a recipient: the user inhales the aerosol, and after the atomization process is completed, measuring blood nicotine (calculated as free nicotine) concentration of the user at 10min, 20min, 30min, 1hr, 1.5hr, 2hr, 3hr, 4hr, 6hr, 8hr, and 12hrDegree, and calculating AUC0→∞(area of plasma concentration curve versus time, reflecting bioavailability/degree of nicotine).
The results are shown in Table 4. The results show that the bioavailability/degree and the like of the examples are superior to those of the control examples.
Test example 2 sensory quality test of electronic cigarette
The method for detecting the sensory quality of the electronic cigarette liquid disclosed by the patent CN201410788599.X comprises the following specific steps:
1) 4 sensory quality detection indexes are set, and the 4 selected sensory quality detection indexes are respectively as follows: the throat attacking (or choking) feeling is characterized by comprising the following components in parts by weight: free nicotine in smoke generated by atomizing the inhaled electronic smoke liquid chokes the throat to cause cough, so that the throat has uncomfortable feeling of choking the smoke, such as oppression feeling and the like; the irritation is that: the smoke generated by atomizing the inhaled electronic cigarette liquid can cause various uncomfortable feelings such as cold, heat, pain, itching, sourness, pungency, spiciness, bitter, salty, numb and astringent sensations to sense organs including oral cavity, throat and nasal cavity; the satisfaction refers to: the smoke strength, concentration and the like generated by atomizing the electronic cigarette liquid can generate comprehensive feelings on sense organs; the comfort level refers to: the smoke generated by atomizing the cigarette liquid of the electronic cigarette influences the comfort degree of the mouth cavity after passing through the suction inlet cavity and the exhalation cavity;
2) smoking the electronic cigarette liquid by a smoker (the method is shown in the application methods of the above embodiments and the control examples), wherein the method comprises the following steps: in smoking evaluation, smoke generated by atomizing cigarette liquid of the electronic cigarette is inhaled through an oral cavity, is swallowed to the lung and is exhaled through a nasal cavity by the throat, and the whole process of feeling and capturing smoke characteristics is realized, wherein 51 smokers are set by the smoker evaluation;
3) and the smoke panel evaluation personnel comprehensively score the sensory quality of the electronic cigarette smoke liquid by adopting a scoring method, and reflect the influence degree of various sensory quality detection indexes on the quality of the electronic cigarette. The scoring method comprises the following steps: the 4 sensory quality detection indexes are respectively scored according to the scores of 0, 5, 10, 15, 20 and 25 (as shown in table 3), and the 4 sensory quality detection indexes can be evaluated independently or integrally according to the sum (highest one percent) of the scoring values. The higher the sensory quality score, the better the quality of the electronic cigarette liquid.
TABLE 3 meaning of score values of sensory quality test indexes
Figure DEST_PATH_GDA0002915422820000151
The minimum score unit of the score value is 0.5.
4) The method for counting the sensory quality detection results of the smoke panel evaluators comprises the following steps: and respectively removing a lowest score and a high score from the scoring values of all the sensory quality detection indexes of all the suckers, and calculating the average value of the effective scoring values of all the sensory quality detection indexes.
The results are shown in Table 5. The results show that the sensory quality of the examples, in particular throat-hitting/choking sensation or satisfaction, is superior to the control examples in terms of comfort.
The following are found in the test:
example (X) was relatively mild and pliable in appearance, relatively good throat-through and/or oral, and relatively good satisfaction and comfort when used; the corresponding comparison examples X-1 and X-3 show more violent, choke the throat, or have larger irritation, and poor throat-passing property and/or oral property, so that a user (especially the user who uses tobacco products for the first time or infrequently) generates certain resistance, and the user refuses to inhale the smoke into the lung or the mouth involuntarily, thereby greatly influencing the satisfaction and the comfort.
The device used in the examples shows the following advantages over the single nozzle or outlet test:
1) the throat choking feeling of the electronic cigarette (generated by free nicotine) is better reduced, and the comfort level is greatly improved: because the smoke of nicotine salt meets the alkaline smoke to generate free nicotine which has a larger throat choking feeling than nicotine salt, the space in the oral cavity and the throat part is many times larger than the space of the small air outlet hole on the cigarette holder, the smoke of the nicotine salt and the alkaline smoke meet through the two air outlets to generate free nicotine, and the amount of the free nicotine generated by the meeting of the smoke of the nicotine salt and the alkaline smoke through the small air outlet hole on the cigarette holder is much less than that of the free nicotine generated by the meeting of the smoke of the nicotine salt and the alkaline smoke through the small air outlet hole on the cigarette holder (because the density of the nicotine salt and the alkali is less and thinner in the larger space, the chance of meeting is less, and the chance of generating the free nicotine through reaction is less), and a considerable proportion of the free nicotine is, the throat choking feeling is much less and the comfort is greatly improved, which is improved more than that the free nicotine is generated before the entrance (such as the pH value of nicotine salt solution is adjusted to be alkaline);
2) the user can really feel two kinds of smoke with different tastes: because the air outlet is directly communicated with the oral cavity, the two air outlet can respectively output the cigarette with one taste into the oral cavity, and a user can feel two kinds of smoke with different tastes.
Table 4-1 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 1 5.2 11.3 Example 2 22.6 39.7
Comparative example 1-1 3.1 7.4 Comparative example 2-1 13.5 24.4
Comparative examples 1 to 2 1.4 2.7 Comparative example 2-2 3.8 8.3
Comparative examples 1 to 3 1.8 3.6 Comparative examples 2 to 3 4.2 9.9
Table 4-2 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 3 13.5 28.8 Example 4 15.8 34.9
Comparative example 3-1 7.9 17.9 Comparative example 4-1 10.2 22.8
Comparative example 3-2 4.1 9.7 Comparative example 4-2 7.7 16.7
Comparative examples 3 to 3 4.5 11.3 Comparative examples 4 to 3 8.9 19.7
Tables 4-3 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
Figure DEST_PATH_GDA0002915422820000152
Figure DEST_PATH_GDA0002915422820000161
Tables 4-4 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 7 14.7 35.5 Example 8 20.3 54.6
Comparative example 7-1 8.9 20.3 Comparative example 8-1 13.7 30.3
Comparative example 7-2 3.4 8.1 Comparative example 8-2 8.8 20.4
Comparative examples 7 to 3 5.1 12.6 Comparative examples 8 to 3 10.4 25.9
Tables 4-5 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 9 22.7 51.3 Example 10 8.8 21.7
Comparative example 9-1 14.6 33.8 Comparative example 10-1 5.5 12.9
Comparative example 9-2 5.1 13.8 Comparative example 10-2 2.4 6.2
Comparative examples 9 to 3 7.8 21.7 Comparative example 10-3 3.8 9.7
Tables 4-6 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 11 21.6 50.4 Example 12 14.6 35.6
Comparative example 11-1 13.8 30.7 Comparative example 12-1 8.5 22.4
Comparative example 11-2 4.8 11.6 Comparative example 12-2 6.3 15.8
Comparative examples 11 to 3 8.2 21.8 Comparative example 12-3 7.6 19.8
Tables 4-7 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 13 23.8 55.8 Example 14 9.3 25.8
Comparative example 13-1 15.4 35.9 Comparative example 14-1 6.2 15.7
Comparative example 13-2 5.8 14.6 Comparative example 14-2 2.7 6.5
Comparative example 13-3 8.9 23.8 Comparative example 14-3 4.5 11.4
Tables 4-8 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 15 21.6 53.8 Example 16 32.7 76.8
Comparative example 15-1 14.5 36.3 Comparative example 16-1 21.6 48.7
Comparative example 15-2 5.8 13.8 Comparative example 16-2 7.6 21.4
Comparative example 15-3 9.3 24.6 Comparative example 16-3 12.8 38.6
Tables 4-9 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 17 23.6 57.4 Example 18 9.5 27.5
Comparative example 17-1 16.5 37.2 Comparative example 18-1 6.1 15.8
Comparative example 17-2 5.8 14.7 Comparative example 18-2 4.3 10.2
Comparative example 17-3 9.8 24.6 Comparative example 18-3 5.3 12.8
Tables 4-10 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 19 26.6 61.5 Example 20 33.5 78.8
Comparative example 19-1 17.3 42.9 Comparative example 20-1 19.8 46.8
Comparative example 19-2 6.8 17.8 Comparative example 20-2 8.8 21.9
Comparative example 19-3 10.2 33.8 Comparative example 20-3 13.6 37.7
Tables 4-11 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 21 39.6 90.7 Example 22 34.2 76.4
Comparative example 21-1 23.4 57.1 Comparative example 22-1 18.7 51.2
Comparative example 21-2 6.5 17.2 Comparative example 22-2 5.8 15.2
Comparative examples 21 to 3 22.7 60.9 Comparative example 22-3 22.8 56.6
Tables 4-12 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 23 25.6 62.7 Example 24 37.7 85.4
Comparative example 23-1 18.4 43.9 Comparative example 24-1 23.5 53.6
Comparative example 23-2 8.9 21.5 Comparative example 24-2 9.4 27.3
Comparative example 23-3 17.3 45.8 Comparative example 24-3 22.9 50.8
Tables 4-13 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
Figure DEST_PATH_GDA0002915422820000162
Figure DEST_PATH_GDA0002915422820000171
Tables 4-14 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 27 17.9 44.9 Example 28 15.6 38.9
Comparative example 27-1 10.5 25.7 ControlExample 28-1 10.2 24.5
Comparative example 27-2 6.4 15.3 Comparative example 28-2 4.7 11.5
Comparative example 27-3 12.5 30.6 Comparative example 28-3 12.0 28.6
Tables 4-15 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 29 26.8 67.3 Example 30 17.3 43.6
Comparative example 29-1 15.1 38.3 Comparative example 30-1 10.6 26.2
Comparative example 29-2 4.4 12.5 Comparative example 30-2 3.8 9.2
Comparative example 29-3 19.4 46.8 Comparative example 30-3 11.2 30.3
Tables 4-16 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 31 15.7 41.3 Example 32 38.3 89.5
Comparative example 31-1 10.2 25.8 Comparative example 32-1 21.6 57.3
Comparative example 31-2 4.1 10.6 Comparative example 32-2 7.8 20.4
Comparative example 31-3 9.1 22.5 Comparative example 32-3 19.6 51.5
Tables 4-17 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 33 17.8 50.4 Example 49 18.6 49.4
Comparative example 33-1 11.4 31.5 Comparative example 49-1 12.3 32.8
Comparative example 33-2 6.7 20.8 Comparative example 49-2 6.9 18.7
Comparative example 33-3 9.5 25.1
Tables 4-18 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 50 26.8 83.7 Example 51 20.4 74.6
Comparative example 50-1 17.8 48.8 Comparative example 51-1 13.1 42.7
Comparative example 50-2 9.6 30.5 Comparative example 51-2 7.2 24.8
Tables 4-19 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 52 10.8 30.7 Example 53 21.8 62.7
Comparative example 52-1 6.2 19.4 Comparative example 53-1 12.1 38.2
Comparative example 52-2 3.6 12.2 Comparative example 53-2 5.6 19.4
Tables 4-20 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 54 42.7 134.6 Example 55 23.8 66.8
Comparative example 54-1 27.2 83.7 Comparative example 55-1 12.3 41.1
Comparative example 54-2 14.8 46.2 Comparative example 55-2 7.7 25.2
Tables 4-21 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 56 28.2 86.7 Example 57 20.6 72.4
Comparative example 56-1 16.3 53.2 Comparative example 57-1 13.7 46.3
Comparative example 56-2 8.4 31.2 Comparative example 57-2 7.1 25.4
Comparative example 57-3 15.1 51.7
Tables 4-22 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 58 18.3 64.7 Example 59 12.8 44.8
Comparative example 58-1 11.5 38.6 Comparative example 59-1 7.2 24.7
Comparative example 58-2 5.9 19.6 Comparative example 59-2 4.5 17.6
Comparative example 58-3 10.4 31.7 Comparative example 59-3 6.8 21.7
Tables 4-23 nicotine analysis: blood concentration C for 10min10min(ng/ml) and AUC0→∞(ng hr/ml) test results
C10min AUC0→∞ C10min AUC0→∞
Example 60 15.7 53.8 Example 61 20.5 71.6
Comparative example 60-1 8.6 29.6 Comparative example 61-1 13.1 43.2
Comparative example 60-2 4.9 18.7 Comparative example 61-2 6.8 23.5
Comparative example 60-3 8.0 26.3
Description of the drawings: in the above tables C10minThe unit is ng/ml; AUC0→∞The unit is ng hr/ml.
TABLE 5-1 sensory quality test results for electronic cigarettes
Figure DEST_PATH_GDA0002915422820000172
Figure DEST_PATH_GDA0002915422820000181
TABLE 5-2 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 2 18.5 15.9 21.4 20.6
Comparative example 2-1 5.8 15.1 15.4 8.2
Comparative examples 2 to 3 16.3 7.4 5.3 7.3
Table 5-3 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 3 21.6 17.4 18.4 20.2
Comparative example 3-1 6.9 16.7 12.3 9.2
Comparative examples 3 to 3 17.2 6.3 7.7 12.5
Comparative examples 3 to 4 20.8 4.1 2.2 13.7
Table 5-4 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 4 20.8 17.1 19.3 19.7
Comparative example 4-1 7.7 16.8 12.2 8.9
Comparative examples 4 to 3 15.6 9.7 10.3 10.2
Tables 5-5 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 5 21.3 20.1 22.4 22.7
Comparative example 5-1 7.8 19.5 15.7 11.2
Comparative examples 5 to 3 14.2 8.3 10.5 12.3
Tables 5-6 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 6 20.1 18.8 23.2 19.4
Comparative example 6-1 3.6 17.3 16.2 12.8
Comparative examples 6 to 3 15.8 9.6 10.5 10.3
Comparative examples 6 to 4 18.6 5.8 3.7 9.7
Tables 5-7 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 7 21.7 20.3 22.8 21.4
Comparative example 7-1 6.3 18.7 15.3 13.8
Comparative examples 7 to 3 15.2 8.8 10.6 11.3
Tables 5-8 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 8 19.6 21.6 22.4 20.7
Comparative example 8-1 5.5 17.6 15.2 13.8
Comparative examples 8 to 3 14.7 9.5 11.4 10.6
Comparative examples 8 to 4 16.8 6.3 7.8 9.8
Tables 5-9 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 9 19.5 21.7 22.6 21.8
Comparative example 9-1 4.6 16.8 16.7 12.4
Comparative examples 9 to 3 15.4 9.2 10.8 11.3
Tables 5-10 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 10 22.8 21.8 18.7 23.6
Comparative example 10-1 6.8 16.6 12.6 14.5
Comparative example 10-3 15.6 9.6 9.4 11.5
Tables 5-11 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 11 18.9 20.5 22.7 20.8
Comparative example 11-1 5.8 6.8 16.5 14.8
Comparative examples 11 to 3 12.2 10.8 12.8 12.3
Comparative examples 11 to 4 17.8 4.2 5.8 8.5
Tables 5-12 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 12 19.3 18.5 21.6 20.5
Comparative example 12-1 5.8 14.5 15.7 15.3
Comparative example 12-3 13.2 10.3 11.2 12.8
Tables 5-13 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 13 18.6 21.6 21.8 20.6
Comparative example 13-1 4.5 15.8 16.3 14.7
Comparative example 13-3 12.4 11.7 12.8 13.7
Comparative examples 13 to 4 16.8 4.8 6.5 9.3
Tables 5-14 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 14 21.4 18.9 18.4 20.7
Comparative example 14-1 7.8 13.6 12.6 13.6
Comparative example 14-3 11.8 9.2 9.7 11.2
Tables 5-15 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 15 19.4 15.6 20.5 16.7
Comparative example 15-1 6.2 12.7 15.3 10.3
Comparative example 15-3 12.2 10.6 10.5 10.5
Comparative examples 15 to 4 17.2 7.2 7.1 8.3
Tables 5-16 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 16 18.8 20.7 23.5 19.9
Comparative example 16-1 4.2 19.9 16.8 12.5
Comparative example 16-3 12.6 10.3 11.7 11.8
Tables 5-17 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 17 20.5 22.5 21.7 20.5
Comparative example 17-1 5.7 20.4 15.8 14.6
Comparative example 17-3 13.2 11.2 10.6 12.7
Tables 5-18 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 18 21.6 23.9 17.8 22.8
Comparative example 18-1 7.9 19.9 12.3 15.4
Comparative example 18-3 11.8 9.6 9.7 12.6
Comparative example 18-4 14.8 6.8 7.3 9.6
Tables 5-19 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 19 18.7 20.8 23.5 21.7
Comparative example 19-1 3.6 16.4 16.5 15.5
Comparative example 19-3 12.8 10.6 11.4 13.8
Tables 5-20 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 20 17.5 19.8 23.8 18.9
Comparative example 20-1 2.8 14.6 16.2 12.6
Comparative example 20-3 12.1 10.2 12.7 10.5
Tables 5-21 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 21 18.6 17.5 23.6 18.9
Comparative example 21-1 3.7 13.8 15.7 11.7
Comparative examples 21 to 3 9.4 10.5 14.8 10.7
Comparative examples 21 to 4 17.8 5.8 6.2 8.9
Tables 5-22 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 22 17.4 20.5 23.2 20.6
Comparative example 22-1 2.2 16.5 16.4 13.8
Comparative example 22-3 4.9 14.7 16.8 11.3
Tables 5-23 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 23 18.8 21.6 20.5 21.9
Comparative example 23-1 4.3 18.5 15.3 14.9
Comparative example 23-3 6.7 15.8 14.9 13.8
Tables 5-24 sensory quality test results for electronic cigarettes
Figure DEST_PATH_GDA0002915422820000191
Figure DEST_PATH_GDA0002915422820000201
Tables 5-25 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 25 18.5 18.5 20.3 19.5
Comparative example 25-1 7.2 15.2 14.7 12.3
Comparative example 25-3 8.8 12.8 12.6 10.7
Tables 5-26 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 26 18.2 20.3 23.3 20.6
Comparative example 26-1 3.2 15.3 15.9 13.2
Comparative example 26-3 8.5 12.4 13.1 12.4
Comparative example 26-4 17.5 6.7 7.5 8.8
Tables 5-27 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 27 21.4 15.4 20.4 17.4
Comparative example 27-1 5.8 13.6 14.1 11.6
Comparative example 27-3 8.9 12.1 12.7 10.2
Tables 5-28 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 28 21.6 18.7 20.8 18.7
Comparative example 28-1 6.7 16.4 14.8 11.6
Comparative example 28-3 8.4 12.6 12.8 10.7
Tables 5-29 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 29 19.6 21.8 21.6 20.6
Comparative example 29-1 4.8 15.7 16.4 14.3
Comparative example 29-3 7.2 11.8 12.5 11.7
Comparative example 29-4 18.5 5.3 6.4 9.3
Tables 5-30 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 30 21.3 16.5 18.6 17.7
Comparative example 30-1 6.5 14.4 12.8 11.7
Comparative example 30-3 8.5 11.8 11.7 10.3
Tables 5-31 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 31 21.5 16.8 19.3 16.6
Comparative example 31-1 7.8 14.6 13.7 10.4
Table 5-32 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 32 20.8 14.5 21.7 13.4
Comparative example 32-1 7.2 13.1 15.4 8.3
Comparative example 32-3 8.6 12.4 12.9 10.3
Comparative example 32-4 14.8 8.7 8.3 8.5
Tables 5-33 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 33 20.4 16.1 19.6 15.6
Comparative example 33-1 5.8 14.6 14.7 9.5
Tables 5-34 sensory quality test results for electronic cigarettes
Figure DEST_PATH_GDA0002915422820000202
Figure DEST_PATH_GDA0002915422820000211
Table 5-35 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 49 21.2 15.3 21.3 16.7
Comparative example 49-1 5.4 14.3 16.3 6.8
Tables 5-36 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 50 20.8 16.3 22.3 16.4
Comparative example 50-1 12.7 14.8 16.3 9.3
Tables 5-37 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 51 20.4 19.2 21.2 20.6
Comparative example 51-1 12.3 17.7 14.8 9.9
Tables 5-38 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 52 21.2 20.8 19.6 19.3
Comparative example 52-1 7.2 18.7 14.7 7.5
Tables 5-39 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 53 20.8 16.7 20.5 19.6
Comparative example 53-1 11.8 14.9 13.4 12.5
Tables 5-40 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 54 20.4 16.2 19.6 18.6
Comparative example 54-1 9.8 14.8 12.2 12.5
Tables 5-41 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 55 20.7 15.4 19.8 17.9
Comparative example 55-1 5.5 14.8 11.8 10.3
Tables 5-42 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 56 20.8 15.1 20.7 16.4
Comparative example 56-1 9.3 14.3 12.2 9.5
Tables 5-43 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 57 21.4 18.7 20.8 19.7
Comparative example 57-1 5.2 17.6 12.7 11.8
Comparative example 57-3 5.6 16.8 12.5 11.3
Tables 5-44 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 58 20.8 19.9 18.6 18.6
Comparative example 58-1 6.8 17.9 10.2 10.5
Comparative example 58-3 4.8 18.2 10.8 9.2
TABLE 5-45 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 59 21.5 18.3 16.8 15.9
Comparative example 59-1 7.8 17.2 8.8 7.6
Comparative example 59-3 5.3 17.4 11.7 9.5
Tables 5-46 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 60 20.8 16.3 18.2 16.4
Comparative example 60-1 7.9 14.8 11.2 11.3
Tables 5-47 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 61 20.5 17.1 19.9 18.6
Comparative example 61-1 10.8 15.8 12.7 12.3
Tables 5-48 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 62-1 23.5 18.3 21.6 22.8
Example 62-2 17.7 17.7 16.7 17.3
Tables 5-49 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 63-1 22.5 17.3 21.5 21.6
Example 63-2 17.9 17.8 16.6 16.1
Table 5-50 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 64-1 23.8 17.6 21.2 23.2
Example 64-2 18.4 18.2 17.7 18.3
Table 5-51 sensory quality test results for electronic cigarettes
Feeling of attacking/choking throat Irritation property Satisfaction feeling Comfort level
Example 65-1 22.6 18.4 22.4 21.8
Example 65-2 16.6 17.9 17.2 16.7

Claims (15)

1. An aerosol generating or atomizing device is characterized by comprising 2 independent and non-communicated atomizing subsystems, wherein each atomizing subsystem respectively comprises a liquid storage chamber or accommodating cavity, an atomizing chamber, a mist or smoke channel or guide part 1 and an atomizing component, the liquid storage chamber or accommodating cavity is directly communicated with the atomizing chamber or is communicated with the atomizing chamber through the guide part 2, one end of the mist or smoke channel or guide part 1 is communicated with the atomizing chamber, the other end of the mist or smoke channel or guide part 1 is respectively communicated with a suction hole, the two liquid storage chambers or accommodating cavities are isolated and not communicated, the two atomizing chambers are isolated and not communicated, the two mist or smoke channels or guide parts 1 are isolated and not communicated, and the two guide parts 2 are isolated and not communicated.
2. The device of claim 1, further comprising a housing, a power supply assembly, and an accessory.
3. An aerosol generating or aerosolizing device comprising a housing, a power supply assembly, accessories, and 2 separate, non-communicating aerosolizing subsystems; the lower shell body comprises a power supply component, an atomization subsystem and two isolated and non-communicated fog or smoke channels, wherein one end of each fog or smoke channel is communicated with the atomization subsystem, and the other end of each fog or smoke channel is communicated with the fog or smoke channel in the upper shell body; the upper shell is a cigarette holder, the long bottom edge of the upper shell is connected with the lower shell, the short bottom edge of the upper shell is provided with two air outlet holes, two isolated and non-communicated mist or smoke channels are arranged in the upper shell, one end of the upper shell is communicated with the air outlet holes, the other end of the upper shell is communicated with the mist or smoke channels in the lower shell, the independent atomization subsystem respectively comprises a liquid storage chamber or accommodating cavity, an atomization chamber, a mist or smoke channel or guide part 1 and an atomization component, the liquid storage chamber or accommodating cavity is directly communicated with the atomization chamber or is communicated with the atomization chamber through a guide part 2, the guide part 1 is the mist or smoke channel in the upper shell and the lower shell, the two liquid storage chambers or accommodating cavities are isolated and non-communicated, the two atomization chambers are isolated and non-communicated, the two guide parts 2 are isolated and non-communicated, and the two guide parts 1 are isolated and non-communicated.
4. A device according to claim 1 or 3, wherein the atomising chamber is a hollow continuous volume.
5. A device according to claim 1 or 3, wherein the nebulization chamber is a non-continuous volume.
6. The apparatus according to claim 1 or 3, wherein the atomizing chamber is a micro-hole in a material containing a plurality of micro-holes.
7. The device according to claim 1 or 3, wherein the atomization chamber is a non-woven fabric, ceramic, glass, metal, or plastic having a plurality of fine pores.
8. A device according to claim 1 or 3, characterized in that the guide 2 is a material containing micro-fine channels.
9. A device according to claim 1 or 3, characterized in that the guide 2 is a nonwoven fabric containing microscopic pores, ceramic, glass, metal, plastic.
10. A device according to claim 1 or 3, characterized in that the guide 2 is a hollow lead-in tube.
11. The device of claim 1 or 3, further comprising a cartridge, a control assembly, and a switch assembly.
12. Device according to claim 1 or 3, characterized in that the atomizing means comprise thermal or/and vibrating or/and compression-type atomizing means.
13. Device according to claim 1 or 3, characterized in that the atomizing means comprise an electrically resistive heating or electromagnetic (oscillatory) heating or/and ultrasonic vibrating atomizing means.
14. A device according to claim 1 or 3, characterised in that the atomizing means comprises an ultrasonic vibration atomizing means.
15. The device of claim 1, wherein the housing has a mouthpiece and an air vent, the air vent is located in the mouthpiece, the air vent is in communication with the air inlet of the aerosolization chamber, and the air outlet of the aerosolization chamber is in communication with the guide member 1.
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CN113679086B (en) * 2021-09-06 2023-03-17 湖北中烟工业有限责任公司 Atomizing agent containing esterified glycerol and preparation method and application thereof
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