CN213346888U

CN213346888U - Device for preparing amlodipine besylate tablets

Info

Publication number: CN213346888U
Application number: CN202021094433.5U
Authority: CN
Inventors: 易志斌; 陈立虹; 李颖; 蒋蒨
Original assignee: Chongqing Kerui Pharmaceutical Group Co Ltd
Current assignee: Chongqing Kerui Pharmaceutical Group Co Ltd
Priority date: 2020-06-12
Filing date: 2020-06-12
Publication date: 2021-06-04
Anticipated expiration: 2030-06-12

Abstract

In order to solve the problem of low efficiency of the device for preparing amlodipine besylate tablets in the prior art, the utility model provides a device for preparing amlodipine besylate tablets, which comprises a bottom plate, a forming plate and a top plate which are arranged from bottom to top in sequence, wherein the shapes of the bottom plate, the forming plate and the top plate are matched and are sequentially attached; a guide channel for ointment flowing is arranged in the top plate and comprises an input port and an output port; two or more tablet holes are formed in the forming plate, the upper ends of the tablet holes correspond to the output port, and cooling cavities which are communicated with each other are formed in the periphery of the tablet holes; the bottom plate is provided with ink pads, the number and the positions of the ink pads correspond to the tablet holes, and the ink pads protrude out of the bottom plate and are located in the tablet holes. This application has formed the tablet shape of old fragrant dew white dew through three-layer superimposed platelike structure mutually supports in proper order, and overall structure is simple to it is reliable in the application, and the film-making is efficient.

Description

Device for preparing amlodipine besylate tablets

Technical Field

The utility model relates to the technical field of tablet forming, in particular to a device for preparing amlodipine besylate tablets.

Background

The amlodipine besylate tablet is mainly used for treating hypertension, chronic stable angina and variant angina. The main component of the amlodipine besylate is amlodipine besylate, and the chemical name is as follows: 3-ethyl-5-methyl-2- (2-aminoethoxymethyl) -4- (2-chlorophenyl) -1, 4-dihydro-6-methyl-3, 5-pyridinedicarboxylate benzenesulfonate; the product is generally prepared into tablets for patients to take in actual use, each tablet is about 5mg (calculated by amlodipine), and the product belongs to western medicine tablets.

In actual production, the existing tablet forming device is large and has low tablet forming efficiency, for example, a western medicine tablet forming device disclosed in chinese patent document CN207137052U forms tablets by means of forming tubes, the forming tubes are complicated to install, and the phenomenon of inconsistent installation of the forming tubes is easy to occur, which results in poor reliability of the device; meanwhile, the phenomenon of low tabletting efficiency exists, for example, 5 to 6 minutes are needed for preparing a batch of (6 tablets) by the equipment after stirring into ointment, so that the industrial development is severely limited; in the prior art, the efficiency can be improved to a certain extent by additionally arranging the forming pipes, for example, the forming pipes are increased by times, and then the motors with larger power are selected to drive more feeding branch pipes, but the cost is increased due to the increase of the power of the motors, and even more, the installation complexity of the whole equipment is increased due to the increase of the forming pipes, so that the reliability of the equipment is reduced; further, chinese patent document CN209548397U also discloses an analgin extrusion molding apparatus, which also has the above-mentioned problems.

SUMMERY OF THE UTILITY MODEL

In order to solve the problem of the inefficiency of the device for preparing amlodipine besylate tablets in the prior art, the utility model provides a device for preparing amlodipine besylate tablets, its aim at improves the efficiency of preparing amlodipine besylate tablets, promotes the reliability of equipment simultaneously.

The utility model provides a technical scheme that its technical problem adopted is: a device for preparing amlodipine besylate tablets comprises a bottom plate, a forming plate and a top plate which are sequentially arranged from bottom to top, wherein the shapes of the bottom plate, the forming plate and the top plate are matched and are sequentially attached; a guide channel for ointment flowing is arranged in the top plate and comprises an input port and an output port; two or more tablet holes are formed in the forming plate, the upper ends of the tablet holes correspond to the output port, and cooling cavities which are communicated with each other are formed in the periphery of the tablet holes; the bottom plate is provided with ink pads, the number and the positions of the ink pads correspond to the tablet holes, and the ink pads protrude out of the bottom plate and are located in the tablet holes.

In the specific application of the medical stainless steel plate, the bottom plate, the forming plate and the top plate can all adopt steel structural members, for example, steel plate structures prepared by conventional medical stainless steel materials are matched in shape, and square, circular or polygonal shapes and the like can be selected; a guide channel for ointment flowing is integrally arranged in the top plate, wherein the guide channel comprises an input port and a plurality of output ports, and the number and the positions of the output ports are consistent with those of the forming holes on the forming plate; the forming plate is internally provided with two or more than two tablet holes, the best application effect is achieved when 6 multiplied by 6 (36 in total) tablet holes are arranged from the angle of convenient installation according to the weight of materials, the tablet holes are through holes, and the peripheries of the tablet holes are also provided with mutually communicated cooling cavities; the bottom plate is integrally provided with ink pads, or the ink pads and the bottom plate are embedded, the number and the positions of the ink pads correspond to those of the tablet holes, and the ink pads protrude out of the bottom plate and are positioned in the tablet holes.

In the application, the top plate is attached to the upper end face of the forming plate, and the lower end face of the forming plate is attached to the bottom plate, wherein the higher the attaching degree is, the less ointment is wasted, and the better the tablet forming is; in order to make the sticking more compact, the surface smoothness of the sticking surface can be optionally improved, or an electromagnet is arranged on the forming plate, the electromagnet can only suck the top plate and the bottom plate after being communicated with an external power supply, and after the tablet is formed, the electromagnet is powered off, so that the top plate and the bottom plate are loosened, and the tablet sticking device is convenient to operate, simple and reliable; the ointment enters the guide channel through the input port and then flows into the tablet holes through the output port to form tablets in sequence; the ink pad on the bottom plate is used for printing marks such as the specification or trademark of the tablet; in order to facilitate rapid tablet forming and improve preparation efficiency, cooling cavities are integrally formed around each tablet hole in the forming plate, wherein the cooling cavities in the forming plate are communicated with each other and are used for helping the ointment to be rapidly cooled in the tablet forming process and improving the tablet forming speed; in order to improve the flow speed of the ointment in the guide channel, an electric heater can be arranged in the top plate.

In practical application, the shape of the aged fragrance dew white dew tablet is formed by mutually matching three layers of sequentially superposed plate-shaped structures, the whole structure is simple, and the application is reliable; the tablet preparation efficiency is high, a batch of tablets (36 tablets) are produced for about 2-3 minutes, the problem of low efficiency of a device for preparing amlodipine besylate tablets in the prior art is solved, and meanwhile, the equipment is reliable.

Drawings

FIG. 1 is a first schematic view of the structure of the present invention;

fig. 2 is a first schematic view of the structural top plate of the present invention;

FIG. 3 is a first schematic view of the structural molding plate of the present invention;

fig. 4 is a first schematic view of the structural base plate of the present invention;

in the figure: 100 top plate, 101 guide channel, 102 output port, 103 input port, 200 forming plate, 201 tablet hole, 202 cooling cavity, 300 bottom plate, 301 stamp pad, 302 positioning pin.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the accompanying drawings and embodiments.

In the specific implementation of the utility model, the device for preparing amlodipine besylate tablets comprises a bottom plate 300, a forming plate 200 and a top plate 100 which are arranged from bottom to top in sequence, wherein the bottom plate 300, the forming plate 200 and the top plate 100 are matched in shape and are sequentially attached; a guide channel 101 for ointment flowing is arranged in the top plate 100 and comprises an input port 103 and an output port 102; two or more tablet holes 201 are formed in the forming plate 200, the upper ends of the tablet holes 201 correspond to the output port 102, and cooling cavities 202 which are communicated with each other are formed around the tablet holes 201; the bottom plate 300 is provided with ink pads 301, the number and the positions of the ink pads 301 correspond to those of the tablet holes 201, and the ink pads 301 protrude out of the bottom plate 300 and are positioned in the tablet holes 201.

In the present embodiment, the top plate 100 is attached to the upper end surface of the forming plate 200, and the lower end surface of the forming plate 200 is attached to the bottom plate 300, wherein the higher the attachment degree is, the less ointment is wasted, and the better the tablet is formed; the ointment enters the guide channel 101 through the input port 103 and then flows into the tablet hole 201 through the output port 102 to form tablets in sequence; the ink pad 301 on the bottom plate 300 is used for printing marks such as specifications or trademarks of tablets; when the tablet is formed, the injection of the ointment is stopped, the top plate 100 is firstly removed to expose the top of the tablet, then the forming plate 200 can be removed or the bottom plate 300 is withdrawn downwards, and the tablet is separated from the tablet hole 201 due to the self-gravity; in order to facilitate rapid tablet forming and improve preparation efficiency, cooling cavities 202 are integrally arranged around each tablet hole 201 in the forming plate, wherein the cooling cavities 202 in the forming plate 200 are communicated with each other and are used for helping ointment to be rapidly cooled in the tablet forming process and improving tablet forming speed; in order to improve the flow speed of the ointment in the guide channel, an electric heater can be arranged in the top plate 100, so that the tablet forming speed can be improved; particularly, the electric heater is arranged in the top plate 100, and the cooling cavity 202 is arranged in the forming plate 200, so that the matching use effect is better, and the tablet forming speed is higher; in other embodiments of the present application, the cooling cavity 202 may be filled with a coolant, or may directly exchange heat through the cavity; the composition and addition of the coolant, the arrangement position of the electric heater and the specific structure of the electric heater are not important for protection of the present application, and a person skilled in the art may select a well-known structure to be directly installed in the forming plate 200 or the top plate 100, and thus will not be described in detail herein.

In practical application, the shape of the aged fragrance dew white dew tablet is formed by mutually matching three layers of sequentially superposed plate-shaped structures, the whole structure is simple, and the application is reliable; the tablet preparation efficiency is high, a batch of 36 tablets are produced for about 2-3 minutes, the problem of low efficiency of the device for preparing amlodipine besylate tablets in the prior art is solved, and meanwhile, the equipment is reliable.

Further, in order to facilitate the alignment of the bottom plate 300 and the forming plate 200 and ensure good drug consistency of each tablet, a positioning device is further arranged between the bottom plate 300 and the forming plate 200 in the application; in the embodiment, the positioning device comprises two positioning holes arranged on the forming plate 200 and two positioning pins 302 integrally arranged on the bottom plate 300, and through the matching between the positioning pins 302 and the positioning holes, the relative positions of each ink pad 301 on the bottom plate 300 and the tablet hole 201 are ensured to be consistent, so that the consistency of the tablet is sequentially improved.

Further, in order to facilitate the medicine to be separated from the medicine piece hole 201, the medicine piece hole 201 is in a shape of a cone with a small top and a big bottom, so that the medicine can be separated downwards, in another embodiment, a smooth layer can be coated on the surface of the medicine piece hole 201 and the surface of the stamp pad 301 on the basis of the shape of the medicine piece hole 201 or independently, so that the medicine can be separated from the medicine piece hole 201 conveniently, and the adhesion between the medicine piece and the medicine piece hole 201 is prevented, and the appearance of the medicine piece is prevented from being influenced; the lubricious layer in this application may be selected from materials known to those skilled in the art, such as plated ceramics, and the like.

It should be understood that the examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that after reading the teachings of the present invention, those skilled in the art may make any number of changes and modifications to the present invention, and such equivalents are intended to be encompassed by the claims appended hereto.

Claims

1. The device for preparing amlodipine besylate tablets is characterized by comprising a bottom plate (300), a forming plate (200) and a top plate (100) which are sequentially arranged from bottom to top, wherein the shapes of the bottom plate (300), the forming plate (200) and the top plate (100) are matched and sequentially attached; a guide channel (101) for ointment flowing is arranged in the top plate (100) and comprises an input port (103) and an output port (102); two or more tablet holes (201) are formed in the forming plate (200), the upper ends of the tablet holes (201) correspond to the output port (102), and cooling cavities (202) which are communicated with each other are further formed around the tablet holes (201); the bottom plate (300) is provided with ink pads (301), the number and the positions of the ink pads (301) correspond to those of the tablet holes (201), and the ink pads (301) protrude out of the bottom plate (300) and are located in the tablet holes (201).

2. The apparatus for preparing amlodipine besylate according to claim 1, wherein a positioning means is further provided between the base plate (300) and the forming plate (200).

3. The apparatus for preparing amlodipine besylate tablets according to claim 1 or 2, wherein the tablet hole (201) is tapered with a small top and a large bottom.

4. The apparatus for preparing amlodipine besylate tablets according to claim 1 or 2, wherein the surface of the tablet hole (201) and the surface of the stamp pad (301) are coated with a smooth layer.

5. The apparatus for preparing amlodipine besylate according to claim 3, wherein the surface of the tablet hole (201) and the surface of the stamp pad (301) are coated with a smooth layer.