CN213345596U - Microcirculation imaging device - Google Patents
Microcirculation imaging device Download PDFInfo
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- CN213345596U CN213345596U CN202021449599.4U CN202021449599U CN213345596U CN 213345596 U CN213345596 U CN 213345596U CN 202021449599 U CN202021449599 U CN 202021449599U CN 213345596 U CN213345596 U CN 213345596U
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Abstract
The utility model relates to a microcirculation image device, include: the device comprises a control device, a positioning device, a scanning device and an optical device; the positioning device, the scanning device and the optical device are respectively connected with the control device; the optical device is also connected with the scanning device; the positioning device is used for acquiring and sending three-dimensional position information of the surface of the detected sample to the control device; the scanning device consists of a movable structure and a scanning probe arranged at the tail end of the movable structure; the control device is used for determining a scanning route according to the three-dimensional position information, controlling the optical device to send laser to the scanning probe, controlling the scanning probe to scan the tested sample by controlling the movable structure according to the scanning route, and finally determining a microcirculation imaging graph of the tested sample according to the scanning result. In the microcirculation imaging device, the control device can control the scanning probe of the scanning device to move or rotate by controlling the moving state of the moving structure, so that the scanning range of the microcirculation imaging device is expanded.
Description
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to microcirculation imaging device.
Background
The microcirculation imaging device is based on an Optical Coherence Tomography Angiography (OCTA) imaging technology, applies motion contrast imaging to high-resolution volume blood flow information, can generate an angiography image within a few seconds, can be used for observing fundus retinal vessel imaging in the field of ophthalmology, further identifies ophthalmic diseases such as glaucoma and fundus macular degeneration, can also be used in the medical fields such as cardiovascular and cerebrovascular diseases, and has wide application prospects.
At present, a scanning probe of a microcirculation imaging device in the related art adopts an X, Y double-shaft galvanometer, the scanning probe of the microcirculation imaging device in the related art cannot move, and only an X-shaft galvanometer lens is driven to move by an X-shaft galvanometer motor of a X, Y double-shaft galvanometer, and a Y-shaft galvanometer lens is driven to move by a Y-shaft galvanometer motor to realize scanning imaging of a target area.
However, since the scanning probe of the related art micro-circulation imaging device is not movable, the scanning range of the related art micro-circulation imaging device is limited by the size of the scanning lens of the X, Y biaxial galvanometer, so that the scanning range of the related art micro-circulation imaging device is small.
SUMMERY OF THE UTILITY MODEL
In view of the above, in order to solve the above problems to some extent, the present application provides a micro-circulation imaging device.
The utility model adopts the following technical scheme: a microcirculation imaging device, comprising: the device comprises a control device, a positioning device, a scanning device and an optical device;
the positioning device, the scanning device and the optical device are respectively connected with the control device; the optical device is also connected with the scanning device;
the positioning device is used for acquiring three-dimensional position information of the surface of a measured sample and sending the three-dimensional position information to the control device so that the control device can determine three-dimensional position data of the measured sample according to the three-dimensional position information; the three-dimensional position data is used for supporting the control device to determine a scanning route of the tested sample;
the scanning device consists of a movable structure and a scanning probe; one end of the movable structure is fixed at a preset position, and the other end of the movable structure is provided with the scanning probe; the movable structure is connected with the control device and used for moving according to the scanning route according to the control signal sent by the control device, and when the movable structure moves, the movable structure drives the scanning probe to move or rotate; the scanning probe is used for receiving the laser sent by the optical device, converging the laser on the surface of the tested sample, receiving the laser reflected by the tested sample and sending the laser reflected by the tested sample to the optical device;
the optical device is used for sending laser to the scanning device according to the control instruction sent by the control device, receiving the laser sent by the scanning device and reflected by the tested sample, presetting the laser reflected by the tested sample to obtain a target optical signal, and sending the target optical signal to the control device; the control device is also used for determining a micro-circulation imaging graph of the tested sample according to the target optical signal.
Furthermore, the movable structure is a multi-joint mechanical arm structure.
Furthermore, the scanning probe is a single-axis scanning galvanometer.
Further, the control device comprises a PC and a human-computer interaction device;
the PC is connected with the human-computer interaction device;
the PC is used for determining three-dimensional position data of the tested sample according to the three-dimensional position information, determining a scanning route of the tested sample according to the three-dimensional position data, controlling the movable structure to move according to the scanning route, and determining a microcirculation imaging graph of the tested sample according to the target optical signal;
the man-machine interaction device is used for displaying the data information sent by the PC and sending a corresponding control instruction to the PC according to the control operation of a user.
Furthermore, the human-computer interaction device is a touch screen.
Furthermore, the human-computer interaction device consists of a display, a keyboard and a mouse.
Further, the positioning device consists of a grating emitter and a camera;
the grating transmitter is used for transmitting structured light to the tested sample;
the camera is used for acquiring the three-dimensional position information of the tested sample and sending the three-dimensional position information to the control device.
Further, the number of the cameras is at least one.
Further, the device also comprises a sample stage;
the sample stage is used for placing the tested sample; the movable structure is fixed on the sample table.
Further, the laser light sent by the optical device comprises sampling laser light and guiding laser light;
the sampling laser is used for supporting a microcirculation imaging device to obtain a microcirculation imaging picture of the tested sample;
the guiding laser is used for facilitating a user to observe a scanning route of the scanning device.
The utility model adopts the above technical scheme, controlling means passes through positioner and acquires the three-dimensional positional information by the sample surface of being surveyed, and determine the scanning route of being surveyed the sample according to this three-dimensional positional information, then, controlling means control optical device sends laser to scanning device, so that scanning device obtains the scanning light source, can carry out laser scanning to being surveyed the sample, controlling means still moves according to the movable structure among the scanning route control scanning device, so that the scanning probe among the movable structure drive scanning device removes or rotates, and then make scanning device scan according to the scanning route and be surveyed the sample, finally make the microcirculation imaging device of this application confirm the microcirculation imaging picture of being surveyed the sample according to the scanning result. Compared with the scanning range of the microcirculation imaging device in the related art, the scanning range of the microcirculation imaging device is limited by the size of the scanning lens of the X, Y biaxial galvanometer, so that the scanning range of the microcirculation imaging device is smaller.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a microcirculation imaging device according to an embodiment of the present invention.
In the figure, 11, a control device; 12. a positioning device; 13. a scanning device; 14. an optical device; 111. a sample stage; 112. a camera; 113. a grating emitter; 114. a movable structure; 115. the probe is scanned.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention will be described in detail below. It is to be understood that the embodiments described are only some embodiments of the invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
Fig. 1 is a schematic structural diagram of a microcirculation imaging device according to an embodiment of the present invention. As shown in fig. 1, the microcirculation imaging device of the present embodiment includes:
control means 11, positioning means 12, scanning means 13 and optical means 14.
Wherein, the positioning device 12, the scanning device 13 and the optical device 14 are respectively connected with the control device 11; the optical device 14 is also connected to the scanning device 13.
The positioning device 12 is configured to obtain three-dimensional position information of the surface of the measured sample, and send the three-dimensional position information to the control device 11, so that the control device 11 determines three-dimensional position data of the measured sample according to the three-dimensional position information; the three-dimensional position data is used for supporting the control device 11 to determine a scanning route of the tested sample; the control device controls the scanning track of the scanning device 13 according to the scanning route, so that the scanning device 13 scans the tested sample according to the scanning route.
Specifically, the type of the positioning device 12 may be various, and it is sufficient to acquire three-dimensional position information of the surface of the sample to be measured and send the three-dimensional position information to the control device 11. For example, the positioning device 12 may be composed of a grating emitter 113 and a camera 112; the grating transmitter is used for transmitting structured light to the tested sample; the camera is configured to acquire three-dimensional position information of the sample to be measured, and send the three-dimensional position information to the control device 11.
Further, the number of cameras constituting the positioning device 12 is at least one. In a specific example, the number of the cameras constituting the positioning device 12 is two, the two cameras are respectively arranged at two preset positions, and are used for acquiring image information of the sample to be measured in two different directions, and respectively sending the acquired image information to the control device 11, where the image information of the two different directions is the three-dimensional position information of the sample to be measured. The control device 11 can determine information such as the physical structure of the surface of the measured sample according to the three-dimensional position information, so that the control device 11 can determine the scanning route of the measured sample according to the physical structure of the surface of the measured sample, and the measured sample can be smoothly scanned.
The scanning device 13 is composed of a movable structure 114 and a scanning probe 115; one end of the movable structure is fixed at a preset position, and the other end of the movable structure is provided with the scanning probe; the movable structure is connected with the control device 11 and is used for moving according to the scanning route according to a control signal sent by the control device 11, and when the movable structure moves, the movable structure drives the scanning probe to move or rotate, so that the scanning probe scans a detected sample according to the scanning route. When scanning a sample to be detected, the scanning probe receives laser sent by the optical device 14, converges the laser on the surface of the sample to be detected, receives laser reflected by the sample to be detected, and sends the laser reflected by the sample to be detected to the optical device 14.
In detail, the type of the movable structure may be multiple, and the scanning probe can be driven to scan according to the scanning route according to the control instruction sent by the control device 11. For example, the mobile structure may be a multi-joint robotic arm structure of the prior art.
The mechanical arm is a complex system with high precision, multiple inputs and multiple outputs, high nonlinearity and strong coupling. Because of its unique operational flexibility, it has been widely used in the fields of industrial assembly, safety and explosion protection. The multi-joint mechanical arm structure can adopt the multi-joint mechanical arm in the field of robots, and the multi-joint mechanical arm is the prior art, so detailed description is not carried out on the structure of the multi-joint mechanical arm structure.
The scanning probe can be of various types, and can support the control device to obtain a microcirculation imaging picture of a measured sample. For example, the scanning probe may be a single axis scanning galvanometer as known in the art. Compare in the microcirculation imaging device of correlation technique and adopt X, Y biax galvanometer, this application adopts the unipolar scanning galvanometer that shakes for the microcirculation imaging device structure of this application is simpler, and the cost is lower.
The optical device 14 is configured to send laser to the scanning device 13 according to a control instruction sent by the control device 11, receive laser reflected by the measured sample sent by the scanning device 13, perform preset processing on the laser reflected by the measured sample to obtain a target optical signal, and send the target optical signal to the control device 11; the control device 11 is further configured to determine a micro-cycle imaging map of the measured sample according to the target optical signal.
In a specific scanning process, the control device 11 controls the optical device 14 to emit laser, the laser is transmitted to the scanning probe through the optical fiber, the scanning probe can converge the laser on the surface of the detected sample, and the laser penetrates through a preset depth when converging on the surface of the detected sample, so that the microcirculation imaging image determined by the control device is an image containing the surface information of the detected sample and the sample information within the preset depth from the surface of the detected sample. When the laser light converges on the sample to be measured, a part of the laser light is reflected to the scanning probe by the reflection of the sample to be measured, and returns to the optical device 14. In the optical device 14, the laser reflected by the tested sample interferes with the laser returned by the reference arm to obtain a target optical signal, and the optical device 14 sends the target optical signal to the control device 11; the control device 11 is used for determining a micro-circulation imaging graph of the tested sample according to the target optical signal.
In the optical device 14, laser emitted from the light source is divided into two paths by the coupler, one path is directed to the sample to be measured, the other path is directed to the reference arm, and the two paths of returned laser interfere with each other in the coupler to obtain the target optical signal.
It should be noted that the optical device 14 of the present application is a conventional technology, and the present application does not structurally modify the optical device, and therefore, the present application does not describe the structure of the optical device 14 in detail.
The utility model adopts the above technical scheme, controlling means passes through positioner and acquires the three-dimensional positional information by the sample surface of being surveyed, and determine the scanning route of being surveyed the sample according to this three-dimensional positional information, then, controlling means control optical device sends laser to scanning device, so that scanning device obtains the scanning light source, can carry out laser scanning to being surveyed the sample, controlling means still moves according to the movable structure among the scanning route control scanning device, so that the scanning probe among the movable structure drive scanning device removes or rotates, and then make scanning device scan according to the scanning route and be surveyed the sample, finally make the microcirculation imaging device of this application confirm the microcirculation imaging picture of being surveyed the sample according to the scanning result. Compared with the scanning range of the microcirculation imaging device in the related art, the scanning range of the microcirculation imaging device is limited by the size of the scanning lens of the X, Y biaxial galvanometer, so that the scanning range of the microcirculation imaging device is smaller.
Further, the control device 11 may be various in kind, and may be capable of performing data acquisition and analysis, and controlling an operation state of the target device by transmitting a control instruction to the target device. For example, the control device 11 may be composed of a PC and a human-computer interaction device.
Wherein, the PC is connected with the human-computer interaction device. The PC is used for determining three-dimensional position data of the detected sample according to the three-dimensional position information, determining a scanning route of the detected sample according to the three-dimensional position data, controlling the movable structure to move according to the scanning route, and determining a microcirculation imaging graph of the detected sample according to the target optical signal; the man-machine interaction device is used for displaying data information sent by the PC and sending a corresponding control instruction to the PC according to the control operation of a user.
Specifically, the PC can automatically determine the scanning route of the sample to be measured according to the three-dimensional position information sent by the positioning device 12, and can also determine the scanning route of the sample to be measured according to a control instruction sent by the user.
The specific process of determining the scanning route of the tested sample by the PC according to the control instruction sent by the user comprises the following steps: the positioning device 12 sends the three-dimensional position information of the detected sample to the PC, and then the PC sends the three-dimensional position information to the human-computer interaction device, so that the human-computer interaction device displays the three-dimensional position information, and a user can obtain the three-dimensional position information through the information displayed by the human-computer interaction device. According to the scheme, the presentation mode of the three-dimensional position information is known in a picture mode. Secondly, the user determines a target scanning area on the picture of the three-dimensional position information according to actual needs, and sends a corresponding scanning instruction to the PC through operating the human-computer interaction device, wherein the scanning instruction comprises the target scanning area, a scanning starting point and a scanning direction of the sample to be detected. The target scanning area is a rectangular area, the scanning starting point is any one of four corner points of the target scanning area, and the scanning direction is along the direction parallel to the boundary line of the target scanning area. And finally, the PC machine determines a scanning route according to the scanning instruction.
A scanning gradient threshold is set in the PC to control the imaging quality of the microcirculation imaging device.
Further, the human-computer interaction device can be a touch screen in the prior art. The human-computer interaction device can also be composed of a display, a keyboard and a mouse in the prior art.
Further, as shown in fig. 1, the microcirculation imaging device of the present application further includes a sample stage 111; the sample stage 111 is used for placing the sample to be tested; the movable structure is fixed on the sample table.
Further, the laser light sent by the optical device 14 includes a sampling laser light and a guiding laser light; the sampling laser is used for supporting the microcirculation imaging device to obtain a microcirculation imaging picture of the tested sample; the pilot laser is used to facilitate the user's view of the scanning path of the scanning device 13.
Specifically, the sampling laser that the microcirculation imaging device of this application adopted is near infrared light, is a light that can not see with the naked eye, consequently, this application makes optical device 14 send sampling laser and guide laser simultaneously, and guide laser can be visible light, because the propagation route of sampling laser and guide laser is unanimous, makes the user know the scanning route of sampling laser through the scanning route of observing guide laser, makes the user know accurately the scanning route at any time, supervises the scanning process of surveyed the sample effectively.
It is understood that the same or similar parts in the above embodiments may be mutually referred to, and the same or similar parts in other embodiments may be referred to for the content which is not described in detail in some embodiments.
It should be noted that, in the description of the present invention, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. In addition, in the description of the present invention, "a plurality" means at least two unless otherwise specified.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Although embodiments of the present invention have been shown and described, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art without departing from the scope of the present invention.
Claims (10)
1. A microcirculation imaging device, comprising: the device comprises a control device, a positioning device, a scanning device and an optical device;
the positioning device, the scanning device and the optical device are respectively connected with the control device; the optical device is also connected with the scanning device;
the positioning device is used for acquiring three-dimensional position information of the surface of a measured sample and sending the three-dimensional position information to the control device so that the control device can determine three-dimensional position data of the measured sample according to the three-dimensional position information; the three-dimensional position data is used for supporting the control device to determine a scanning route of the tested sample;
the scanning device consists of a movable structure and a scanning probe; one end of the movable structure is fixed at a preset position, and the other end of the movable structure is provided with the scanning probe; the movable structure is connected with the control device and used for moving according to the scanning route according to the control signal sent by the control device, and when the movable structure moves, the movable structure drives the scanning probe to move or rotate; the scanning probe is used for receiving the laser sent by the optical device, converging the laser on the surface of the tested sample, receiving the laser reflected by the tested sample and sending the laser reflected by the tested sample to the optical device;
the optical device is used for sending laser to the scanning device according to the control instruction sent by the control device, receiving the laser sent by the scanning device and reflected by the tested sample, presetting the laser reflected by the tested sample to obtain a target optical signal, and sending the target optical signal to the control device; the control device is also used for determining a micro-circulation imaging graph of the tested sample according to the target optical signal.
2. The microcirculation imaging device of claim 1, wherein the mobile structure is a multi-joint robotic arm structure.
3. The microcirculation imaging device of claim 1, wherein the scanning probe is a single axis scanning galvanometer.
4. The microcirculation imaging device of claim 1, wherein the control device includes a PC and a human-computer interaction device;
the PC is connected with the human-computer interaction device;
the PC is used for determining three-dimensional position data of the tested sample according to the three-dimensional position information, determining a scanning route of the tested sample according to the three-dimensional position data, controlling the movable structure to move according to the scanning route, and determining a microcirculation imaging graph of the tested sample according to the target optical signal;
the man-machine interaction device is used for displaying the data information sent by the PC and sending a corresponding control instruction to the PC according to the control operation of a user.
5. The microcirculation imaging device of claim 4, wherein the human-computer interaction device is a touch screen.
6. The microcirculation imaging device of claim 4, wherein the human-computer interaction device is composed of a display, a keyboard and a mouse.
7. The microcirculation imaging device of claim 1, wherein the positioning device is comprised of a grating emitter and a camera;
the grating transmitter is used for transmitting structured light to the tested sample;
the camera is used for acquiring the three-dimensional position information of the tested sample and sending the three-dimensional position information to the control device.
8. The microcirculation imaging device of claim 7, wherein the number of cameras is at least one.
9. The microcirculation imaging device of claim 1, further comprising a sample stage;
the sample stage is used for placing the tested sample; the movable structure is fixed on the sample table.
10. The microcirculation imaging device of claim 1, wherein the laser light sent by the optical device includes a sampling laser light and a guiding laser light;
the sampling laser is used for supporting a microcirculation imaging device to obtain a microcirculation imaging picture of the tested sample;
the guiding laser is used for facilitating a user to observe a scanning route of the scanning device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021449599.4U CN213345596U (en) | 2020-07-21 | 2020-07-21 | Microcirculation imaging device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202021449599.4U CN213345596U (en) | 2020-07-21 | 2020-07-21 | Microcirculation imaging device |
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| CN213345596U true CN213345596U (en) | 2021-06-04 |
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| CN202021449599.4U Active CN213345596U (en) | 2020-07-21 | 2020-07-21 | Microcirculation imaging device |
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