CN213266465U - Single-sample full-automatic nucleic acid closed extraction instrument - Google Patents
Single-sample full-automatic nucleic acid closed extraction instrument Download PDFInfo
- Publication number
- CN213266465U CN213266465U CN202021968423.XU CN202021968423U CN213266465U CN 213266465 U CN213266465 U CN 213266465U CN 202021968423 U CN202021968423 U CN 202021968423U CN 213266465 U CN213266465 U CN 213266465U
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- nucleic acid
- chamber
- fixedly connected
- placing
- plate
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- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 43
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 43
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 43
- 238000000605 extraction Methods 0.000 title abstract description 34
- 238000012360 testing method Methods 0.000 claims abstract description 48
- 230000007246 mechanism Effects 0.000 claims abstract description 12
- 230000003028 elevating effect Effects 0.000 claims abstract description 4
- 238000007789 sealing Methods 0.000 claims description 12
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 238000012864 cross contamination Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 description 6
- 238000005192 partition Methods 0.000 description 5
- 241000973497 Siphonognathus argyrophanes Species 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a closed appearance that draws of full-automatic nucleic acid of single sample, relate to nucleic acid extraction appearance field, the power distribution box comprises a box body, the horizontal baffle that sets up of inside middle part fixedly connected with of box, the box divide into through the baffle and draws the chamber and place the chamber, the last inside wall that draws the chamber is connected with through elevating system and draws the head, the upper end middle part of baffle has been seted up and has been drawn first phase-match round hole, the inside below of placing the chamber is equipped with the arm-tie, the lower extreme of arm-tie passes through slide mechanism and is connected with the lower inside wall of placing the chamber, the upper end right side of arm-tie is provided with places the board, the upper end fixedly connected with rack of placing the board, a plurality of evenly distributed's jack. The utility model discloses be convenient for place the test tube and carry out nucleic acid extraction inside the box, and seal the mouth of pipe of test tube when can not drawing, avoid nucleic acid cross contamination in the test tube, and be convenient for get and put the test tube, the people of being convenient for use.
Description
Technical Field
The utility model relates to a nucleic acid extraction appearance field, in particular to single sample full-automatic nucleic acid closed extraction appearance.
Background
The nucleic acid extractor is an instrument which automatically finishes the extraction work of sample nucleic acid by using a matched nucleic acid extraction reagent and is divided into two types: one type is large-scale automated, commonly referred to as automated liquid workstations; the other type is a small-sized automatic nucleic acid extractor, the extraction and purification process is automatically finished by using a packaged matched reagent, and a large-sized automatic liquid workstation is high in equipment cost and operation cost and is suitable for extracting thousands of same samples at a time, so that the number of applications is reduced really; and small-sized automatic instruments are more and more applied because of low instrument equipment and operation cost and convenient operation.
At present, when the nucleic acid extraction appearance was drawed the nucleic acid in the test tube, the full-automatic nucleic acid extraction appearance of most all adopted the magnetic bead method to extract nucleic acid, and at the extraction in-process, the test tube mouth all is open to all be to the test tube group of many samples extraction design, the test tube group is an open extraction platform, does not set up the test tube lid on these test tubes on the test tube group, cross contamination easily in the nucleic acid extraction in-process, people's use of not being convenient for.
Therefore, it is necessary to invent a single-sample fully automatic closed nucleic acid extractor to solve the above problems.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a closed extractor of full-automatic nucleic acid of single sample, when solving the nucleic acid extraction appearance that proposes in the above-mentioned background art and extracting the nucleic acid in the test tube, most full-automatic nucleic acid extraction appearance all adopts the magnetic bead method to extract nucleic acid, at the extraction in-process, the test tube mouth all is open, and all be to the test tube group of many samples extraction design, the test tube group is an open extraction platform, do not set up the test tube lid on these test tubes on the test tube group, at the easy cross contamination of nucleic acid extraction in-process, the problem that people used not convenient for.
In order to achieve the above object, the utility model provides a following technical scheme: a single-sample full-automatic nucleic acid closed extraction instrument comprises a box body, wherein a transversely arranged partition plate is fixedly connected to the middle inside of the box body, the box body is divided into an extraction cavity and a placement cavity through the partition plate, the upper inner side wall of the extraction cavity is connected with an extraction head through a lifting mechanism, a round hole matched with the extraction head is formed in the middle of the upper end of the partition plate, a pull plate is arranged below the inside of the placement cavity, the lower end of the pull plate is connected with the lower inner side wall of the placement cavity through a sliding mechanism, a placement plate is arranged on the right side of the upper end of the pull plate, a placement frame is fixedly connected to the upper end of the placement plate, a plurality of uniformly distributed insertion holes are formed in the upper end of the placement frame, test tubes are inserted into the insertion holes, a sealing plate is rotatably connected to the upper parts of the test tubes through, the output of servo motor rotates through the shaft coupling and is connected with the threaded rod, place the board through screw hole and threaded rod threaded connection, the front side of drawing the chamber and placing the chamber is opening the setting, and draws the chamber and place the front side in chamber and all be connected with first chamber door and second chamber door through the hinge rotation.
Preferably, elevating system includes electric telescopic handle, electric telescopic handle's upper end fixedly connected with mounting panel, the upper end of mounting panel with draw the last inside wall fixed connection in chamber, electric telescopic handle's lower extreme fixedly connected with lifter plate, the lower extreme of lifter plate with draw first fixed connection.
Preferably, the sliding mechanism comprises two sliding rails and two guide blocks, the two sliding rails are fixedly connected with the lower inner side wall of the placing cavity, the two guide blocks are respectively connected with the two sliding rails in a sliding manner, the upper ends of the two guide blocks are fixedly connected with the lower end of the pulling plate, and the middle part of the front side of the pulling plate is fixedly connected with the pulling block.
Preferably, the lower end of the placing plate is fixedly connected with two limiting sliding blocks which are symmetrically distributed, and the upper end of the pulling plate is provided with two matched limiting sliding grooves which are matched with the limiting sliding blocks.
Preferably, the upper end of the placing plate is fixedly connected with a rubber pad.
Preferably, the lower end of the front side of the first box door is fixedly connected with a first handle, and the lower end of the front side of the second box door is fixedly connected with a second handle.
The utility model discloses a technological effect and advantage:
1. through the mutual matching of the box body, the partition board, the placing cavity, the pulling plate, the placing plate, the servo motor, the threaded rod, the placing frame, the test tubes, the extracting cavity, the lifting mechanism and the extracting head, the threaded rod can be driven to rotate through the servo motor, the threaded rod can drive the placing plate to move through rotation, the placing plate drives the placing frame to move, the placing frame drives the test tubes to move, one test tube can be enabled to correspond to the position of the round hole, the extracting head is driven to move downwards through the lifting mechanism, the extracting head can be inserted into the corresponding test tube, the nucleic acid in the test tube can be extracted, and the cross contamination of the nucleic acid in the test tube is avoided;
2. through the spring hinge and the sealing cover, when nucleic acid in the test tube does not need to be extracted, the spring hinge applies torsional force to the sealing plate to enable the sealing plate to rotate and close with the tube opening of the test tube, so that the nucleic acid in the test tube can be protected, and during extraction, the extraction head can apply pressure to the sealing plate to open the sealing plate, so that the nucleic acid can be extracted;
3. through mutually supporting of arm-tie, two guide rails and two guide blocks that are equipped with, the pulling arm-tie can drive places board and rack and move to the outside, and the rack can drive a plurality of test tubes and move to the outside, is convenient for place the test tube and take.
Drawings
Fig. 1 is a schematic front structural view of the present invention.
Fig. 2 is a schematic front sectional view of the present invention.
Fig. 3 is a schematic structural diagram of the test tube of the present invention.
Fig. 4 is a schematic side view of the placing board of the present invention.
In the figure: 1. a box body; 2. a partition plate; 3. extracting a head; 4. pulling a plate; 5. placing the plate; 6. placing a rack; 7. a test tube; 8. a servo motor; 9. a threaded rod; 10. a first door; 11. a second door; 12. an electric telescopic rod; 13. mounting a plate; 14. a lifting plate; 15. a sealing plate; 16. a slide rail; 17. a guide block; 18. pulling the block; 19. a limiting slide block; 20. a rubber pad; 21. a first handle; 22. a second handle.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
The utility model provides a single sample full-automatic nucleic acid closed extractor as shown in figures 1-4, which comprises a box body 1, the middle part of the interior of the box body 1 is fixedly connected with a transverse baffle 2, the box body 1 is divided into an extracting cavity and a placing cavity by the baffle 2, the upper inner side wall of the extracting cavity is connected with an extracting head 3 by a lifting mechanism, the middle part of the upper end of the baffle 2 is provided with a round hole matched with the extracting head 3, the lower part of the interior of the placing cavity is provided with a pulling plate 4, the lower end of the pulling plate 4 is connected with the lower inner side wall of the placing cavity by a sliding mechanism, the right side of the upper end of the pulling plate 4 is provided with a placing plate 5, the upper end of the placing plate 5 is fixedly connected with a placing rack 6, the upper end of the placing rack 6 is provided with a plurality of jacks which are evenly distributed, test, spring hinge is hinge and torsion spring intercombination and constitutes, makes the hinge have the torsional force, and for prior art, the upper end left side fixedly connected with servo motor 8 of arm-tie 4, servo motor 8's output rotates through the shaft coupling and is connected with threaded rod 9, places board 5 and passes through screw hole and 9 threaded connection of threaded rod, draws the chamber and places the front side in chamber and be the setting of opening, and draw the chamber and place the front side in chamber and all be connected with first chamber door 10 and second chamber door 11 through hinge rotation.
As shown in fig. 2, elevating system includes electric telescopic handle 12, electric telescopic handle 12's upper end fixedly connected with mounting panel 13, mounting panel 13's upper end and the last inside wall fixed connection who draws the chamber, electric telescopic handle 12's lower extreme fixedly connected with lifter plate 14, lifter plate 14's lower extreme and extraction head 3 fixed connection, electric telescopic handle 12 drives lifter plate 14 and moves down, lifter plate 14 drives extraction head 3 and moves down, make extraction head 3 pass the round hole and insert and carry out nucleic acid extraction in the corresponding test tube 7.
As shown in fig. 2, the sliding mechanism includes two slide rails 16 and two guide blocks 17, two slide rails 16 all with place the lower inside wall fixed connection in chamber, two guide blocks 17 respectively with two slide rails 16 sliding connection, the upper end of two guide blocks 17 all with the lower extreme fixed connection of arm-tie 4, the front side middle part fixed connection of arm-tie 4 draws piece 18, be convenient for people pull out arm-tie 4 from placing the chamber, be convenient for people to take and put test tube 7.
As shown in fig. 4, the lower end of the placing plate 5 is fixedly connected with two symmetrically distributed limiting sliders 19, and the upper end of the pulling plate 4 is provided with two matching limiting sliding grooves matched with the limiting sliders 19, so that the placing plate 5 can move transversely more stably.
As shown in FIG. 2, a rubber pad 20 is fixedly connected to the upper end of the placing plate 5, so as to prevent the test tube 7 from being damaged due to collision with the placing plate 5 when the test tube 7 is placed.
As shown in fig. 1, a first handle 21 is fixedly connected to a lower end of a front side of the first door 10, so that people can open the first door 10 conveniently, and a second handle 22 is fixedly connected to a lower end of a front side of the second door 11, so that people can open the second door 11 conveniently.
The utility model discloses the theory of operation:
when the device is used, the second box door 11 is opened, the pulling plate 4 is pulled out, so that the placing plate 5 and the placing rack 6 can be pulled out, the plurality of test tubes 7 are respectively inserted into the plurality of jacks on the placing rack 6, the pulling plate 4 is pushed into the placing cavity and the second box door 11 is closed, when nucleic acid in the test tubes 7 does not need to be extracted, the spring hinges apply torsional force to the sealing plate 15, so that the sealing plate 15 rotates and is closed with the tube orifices of the test tubes 7, so that the nucleic acid in the test tubes 7 can be protected, when the nucleic acid needs to be extracted, the servo motor 8 can drive the threaded rod 9 to rotate, the threaded rod 9 can drive the placing plate 5 to move, the placing plate 5 drives the placing rack 6 to move, the placing rack 6 drives the plurality of test tubes 7 to move, one test tube 7 can correspond to the position of the round hole, the electric telescopic rod 12 drives the lifting plate 14 to move, make extraction head 3 pass the round hole and exert pressure to sealing plate 15, open sealing plate 15 to can insert extraction head 3 and extract the nucleic acid in test tube 7, avoid the nucleic acid cross contamination in the test tube 7.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.
Claims (6)
1. The utility model provides a closed appearance of extracting of full-automatic nucleic acid of single sample which characterized in that: comprises a box body (1), the middle part inside the box body (1) is fixedly connected with a transverse clapboard (2), the box body (1) is divided into a drawing cavity and a placing cavity by the clapboard (2), the upper inner side wall of the drawing cavity is connected with a drawing head (3) by a lifting mechanism, the middle part of the upper end of the clapboard (2) is provided with a round hole matched with the drawing head (3), a pulling plate (4) is arranged below the placing cavity, the lower end of the pulling plate (4) is connected with the lower inner side wall of the placing cavity by a sliding mechanism, the right side of the upper end of the pulling plate (4) is provided with a placing plate (5), the upper end of the placing plate (5) is fixedly connected with a placing rack (6), the upper end of the placing rack (6) is provided with a plurality of jacks which are uniformly distributed, test tubes (7) are inserted in the jacks, and sealing plates (15) are rotatably connected above the test tubes (7, the upper end left side fixedly connected with servo motor (8) of arm-tie (4), the output of servo motor (8) rotates through the shaft coupling and is connected with threaded rod (9), place board (5) through screw hole and threaded rod (9) threaded connection, the front side of drawing the chamber and placing the chamber is and opens the setting, and draws the chamber and place the front side in chamber all to be connected with first chamber door (10) and second chamber door (11) through the hinge rotation.
2. The single-sample fully-automatic closed nucleic acid extractor according to claim 1, wherein: elevating system includes electric telescopic handle (12), the upper end fixedly connected with mounting panel (13) of electric telescopic handle (12), the upper end of mounting panel (13) and the last inside wall fixed connection who draws the chamber, the lower extreme fixedly connected with lifter plate (14) of electric telescopic handle (12), the lower extreme of lifter plate (14) with draw first (3) fixed connection.
3. The single-sample fully-automatic closed nucleic acid extractor according to claim 1, wherein: slide mechanism includes two slide rails (16) and two guide block (17), two slide rail (16) all with place the lower inside wall fixed connection in chamber, two guide block (17) respectively with two slide rail (16) sliding connection, two the upper end of guide block (17) all with the lower extreme fixed connection of arm-tie (4), the front side middle part fixedly connected with of arm-tie (4) draws piece (18).
4. The single-sample fully-automatic closed nucleic acid extractor according to claim 1, wherein: the lower end of the placing plate (5) is fixedly connected with two limiting sliding blocks (19) which are symmetrically distributed, and the upper end of the pulling plate (4) is provided with two matched limiting sliding grooves which are matched with the limiting sliding blocks (19).
5. The single-sample fully-automatic closed nucleic acid extractor according to claim 1, wherein: the upper end of the placing plate (5) is fixedly connected with a rubber pad (20).
6. The single-sample fully-automatic closed nucleic acid extractor according to claim 1, wherein: the lower end of the front side of the first box door (10) is fixedly connected with a first handle (21), and the lower end of the front side of the second box door (11) is fixedly connected with a second handle (22).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202021968423.XU CN213266465U (en) | 2020-09-10 | 2020-09-10 | Single-sample full-automatic nucleic acid closed extraction instrument |
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CN202021968423.XU CN213266465U (en) | 2020-09-10 | 2020-09-10 | Single-sample full-automatic nucleic acid closed extraction instrument |
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CN213266465U true CN213266465U (en) | 2021-05-25 |
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CN202021968423.XU Expired - Fee Related CN213266465U (en) | 2020-09-10 | 2020-09-10 | Single-sample full-automatic nucleic acid closed extraction instrument |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114061280A (en) * | 2022-01-15 | 2022-02-18 | 南通合瑞源生物科技有限公司 | Drying equipment of test tube is kept in nucleic acid |
-
2020
- 2020-09-10 CN CN202021968423.XU patent/CN213266465U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114061280A (en) * | 2022-01-15 | 2022-02-18 | 南通合瑞源生物科技有限公司 | Drying equipment of test tube is kept in nucleic acid |
CN114061280B (en) * | 2022-01-15 | 2022-03-22 | 南通合瑞源生物科技有限公司 | Drying equipment of test tube is kept in nucleic acid |
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GR01 | Patent grant | ||
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CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210525 |