CN213246264U

CN213246264U - Cigarette smoke exposure device

Info

Publication number: CN213246264U
Application number: CN202021584979.9U
Authority: CN
Inventors: 谢诒诚; 谢强敏; 梁禹; 徐达; 杨永辉; 沈剑; 贾永良; 何建影
Original assignee: Hangzhou Breath Smooth Biopharmaceutical Technology Co ltd
Current assignee: Hangzhou Breath Smooth Biopharmaceutical Technology Co ltd
Priority date: 2020-08-04
Filing date: 2020-08-04
Publication date: 2021-05-25
Anticipated expiration: 2030-08-04

Abstract

The utility model provides a cigarette smog exposes device, including the seal box, be equipped with the inlet port on one side lateral wall of seal box, be equipped with cigarette holder type smoke generator on the inlet port, be equipped with the venthole on the opposite side lateral wall of seal box, the venthole is connected with the aspiration pump, the upper portion of seal box is equipped with can dismantle the apron, can dismantle and be equipped with the pipe of discharging fume on the apron, the other end of the pipe of discharging fume is equipped with the exhaust fan, the inside of seal box is equipped with the animal cage. Compared with the prior art, the manufactured experimental animal model is uniform, safe, effective and high in repeatability, and is beneficial to the scientificity of the experiment; the exposure device has the advantages that the main parts are easy to disassemble and assemble, convenient to maintain and clean and simple to operate; the price is cheap, the cost is low, and the main equipment can also come from other equipment; the operation process is controllable, the observation is convenient, and the exposure process can be adjusted; can effectively reduce the death rate of experimental animals, has low environmental pollution and little harm to experimental personnel.

Description

Cigarette smoke exposure device

[ technical field ] A method for producing a semiconductor device

The utility model relates to an experimental apparatus technical field, in particular to cigarette smog exposes device.

[ background of the invention ]

Existing evidence clearly indicates that smoking is unhealthy. The number of Chinese smokers is about 3.5 hundred million in 2019, about 13 hundred million people smoke globally at present, and 490 million people die due to smoking annually. Smoking causes damage to respiratory immune function, lung structure and lung function, causing a variety of respiratory diseases. A number of studies have demonstrated that smoking can lead to chronic obstructive pulmonary disease and juvenile asthma, increasing the risk of tuberculosis and other respiratory infections.

Due to the deterioration of the environment and the serious air pollution, respiratory diseases in China have a high tendency in recent years, wherein smoking is the most main pathogenic factor of chronic obstructive pulmonary disease in human beings.

In the course of studying COPD, it is now widely accepted to establish experimental animal models by cigarette smoke exposure in order to mimic the pathogenesis of the disease. The existing domestic smoke exposure device has the defects of high equipment cost, large floor area, non-uniform smoke, incapability of standardizing the established animal model, even death of animals and the like.

[ Utility model ] content

An object of the utility model is to provide a cigarette smog exposes device to overcome among the prior art smog expose device have equipment cost high, area reach, smog inhomogeneous, the animal model of establishing can not standardize, lead to shortcomings such as animal death even.

In order to achieve the above object, the utility model provides a following technical scheme:

the application discloses cigarette smog exposes device, including seal box, cigarette holder type smoke generator, aspiration pump, exhaust fan, exhaust pipe and animal cage, be equipped with the inlet port on one side lateral wall of seal box, be equipped with cigarette holder type smoke generator on the inlet port, be equipped with the venthole on the opposite side lateral wall of seal box, the venthole is connected with the aspiration pump, the upper portion of seal box is equipped with can dismantle the apron, can dismantle to be equipped with on the apron and discharge fume the pipe, the other end of discharging fume the pipe is equipped with the exhaust fan, the inside of seal box is equipped with the animal cage.

Preferably, the air pump is connected with the air outlet through a transparent hose, and a smoke filter is arranged at an inlet of the transparent hose to prevent smoke from entering the air pump to damage the pump body.

Preferably, the animal cage is provided with a plurality of grids which are separated by using wire meshes and are placed alternately in the experiment process, so that the condition that the animals gather at corners to cause uneven exposure and even suffocate due to overcrowding is prevented.

Preferably, a plurality of air holes which can be closed or opened are formed in the front side and the rear side of the sealing box, so that animals are prevented from being killed due to oxygen deficiency or overhigh smoke concentration.

Preferably, the detachable cover plate is provided with a positive and negative barometer, the detection end of the positive and negative barometer is positioned inside the seal box, and the data display end of the positive and negative barometer is positioned outside the seal box.

Preferably, a pipe valve is arranged on the smoke exhaust pipe.

The utility model has the advantages that:

(1) the manufactured experimental animal model is uniform, safe, effective and high in repeatability, and is beneficial to the scientificity of the experiment;

(2) the exposure device has the advantages that the main parts are easy to disassemble and assemble, convenient to maintain and clean and simple to operate;

(3) the price is cheap, the cost is low, and the main equipment can also come from other equipment, for example, the air pump can adopt the air pump of the filtering equipment;

(4) the box body of the seal box is made of transparent PVC material, so that the observation and the cleaning are convenient, the operation process is controllable, the observation is convenient, and the exposure process can be adjusted;

(5) can effectively reduce the death rate of experimental animals, has high safety, low environmental pollution and little harm to experimental personnel.

(6) The number of the experimental animals for molding can be flexibly adjusted.

The features and advantages of the present invention will be described in detail by embodiments with reference to the accompanying drawings.

[ description of the drawings ]

FIG. 1 is a schematic view of a cigarette smoke exposure device of the present invention;

fig. 2 is a schematic structural view of the animal cage of the present invention.

In the figure: 1-a seal box, 11-a detachable cover plate, 12-an air inlet, 13-an air outlet, 2-a cigarette holder type smoke generator, 3-an air pump, 4-an exhaust fan, 5-a smoke exhaust pipe, 51-a pipe valve, 6-a transparent hose, 61-a smoke filter, 7-an air vent, 8-a positive and negative pressure gauge, 9-an animal cage, 91-a grid and 92-a wire netting.

[ detailed description ] embodiments

In order to make the objects, technical solutions and advantages of the present invention more clear, the present invention is further described in detail through the accompanying drawings and embodiments. It should be understood, however, that the description herein of specific embodiments is only intended to illustrate the invention and not to limit the scope of the invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.

Referring to fig. 1 and 2, the cigarette smoke exposure device is arranged in a fume hood, an experimental animal needing to be molded is divided into a plurality of grids and is arranged in a grid 91 of an experimental animal cage 9, then the experimental animal cage 9 is linked and is arranged in a sealing box 1, a detachable cover plate 11 is closed, cigarettes are arranged on a cigarette holder type smoke generator 2 and are ignited, and an air suction pump 3 is opened;

the sealed box 1 is filled with cigarette smoke and the suction pump 3 is turned off when the cigarette is burnt out or the smoke concentration is sufficient.

Observing the state of the experimental animal, opening the air holes 7 at the front side and the rear side of the plurality of seal boxes 1 according to the actual condition, introducing oxygen through the air holes 7 when necessary, and monitoring the air pressure change condition in the seal boxes 1 through the positive and negative barometers 8. At the moment, the experimental animals are exposed to the cigarette smoke, and because the space distribution is reasonable and fresh air exchange exists, the death of the experimental animals can be avoided to the maximum extent.

When the exposure is finished, the pipe valve 51 of the exhaust pipe 5 is opened, the exhaust fan 4 is opened to quickly exhaust the smoke in the sealed box 1, and simultaneously, fresh air is supplemented into the sealed box 1 to restore the original atmosphere of the experimental animal.

And taking out the experimental animal after the experiment is finished, and disassembling and cleaning the device.

The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modification, equivalent replacement or improvement made within the spirit and principle of the present invention should be included in the present invention.

Claims

1. A cigarette smoke exposure apparatus characterized by: including seal box (1), cigarette holder type fog generator (2), aspiration pump (3), exhaust fan (4), tub (5) and animal cage (9) of discharging fume, be equipped with inlet port (12) on one side lateral wall of seal box (1), be equipped with cigarette holder type fog generator (2) on inlet port (12), be equipped with venthole (13) on the opposite side lateral wall of seal box (1), venthole (13) are connected with aspiration pump (3), the upper portion of seal box (1) is equipped with can dismantle apron (11), can dismantle and be equipped with tub (5) of discharging fume on apron (11), the other end of tub (5) of discharging fume is equipped with exhaust fan (4), the inside of seal box (1) is equipped with animal cage (9).

2. A cigarette smoke exposure apparatus as in claim 1 wherein: the air pump (3) is connected with the air outlet hole (13) through a transparent hose (6), and a smoke filter (61) is arranged at an inlet of the transparent hose (6).

3. A cigarette smoke exposure apparatus as in claim 1 wherein: the animal cage frame (9) is provided with a plurality of grids (91), and the grids (91) are separated by iron wires (92).

4. A cigarette smoke exposure apparatus as in claim 1 wherein: the front side and the rear side of the sealing box (1) are provided with a plurality of air holes (7) which can be closed or opened.

5. A cigarette smoke exposure apparatus as in claim 1 wherein: the detachable cover plate (11) is provided with a positive and negative barometer (8), the detection end of the positive and negative barometer (8) is positioned inside the seal box (1), and the data display end of the positive and negative barometer (8) is positioned on the outer side of the seal box (1).

6. A cigarette smoke exposure apparatus as in claim 1 wherein: and a pipe valve (51) is arranged on the smoke exhaust pipe (5).