CN213172304U - Sample is preserved and is handled card box - Google Patents
Sample is preserved and is handled card box Download PDFInfo
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- CN213172304U CN213172304U CN202021335958.3U CN202021335958U CN213172304U CN 213172304 U CN213172304 U CN 213172304U CN 202021335958 U CN202021335958 U CN 202021335958U CN 213172304 U CN213172304 U CN 213172304U
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Abstract
The utility model discloses a sample is preserved and is handled card box, include: the first clamping box is used for containing a sample, and a first box cover for closing the first clamping box is detachably arranged on the first clamping box; a second cartridge detachably provided on the first cartridge, the second cartridge storing a processing liquid; and the opener is arranged at the junction of the first card box and the second card box and can puncture the junction and conduct the first card box and the second card box. Use the utility model discloses when well sample preserved processing card box, the save of sample and sample transfer all not with external contact, reduced the influence of the quality of drawing to nucleic acid, reduced the influence of interpreting to nucleic acid testing result.
Description
Technical Field
The utility model relates to a biological detection technical field, more specifically say, relate to a sample is preserved and is handled card box.
Background
The extraction of sample nucleic acid has been an important problem hindering the development of nucleic acid detection, especially for complex samples such as feces, sputum and the like, long-term storage is required after the sample is extracted, and sample treatment is required before the sample is extracted. However, the samples are currently exposed to air during storage, and if the samples are contaminated, large-scale transmission and infection may occur. When the stored sample is transferred to a sample for processing, the sample can contact with the outside air, the extraction quality of the nucleic acid can be influenced, and the interpretation of the nucleic acid detection result is finally influenced.
Therefore, how to improve the quality of nucleic acid extraction is an urgent technical problem to be solved by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model aims to solve the technical problem how to improve the extraction quality of nucleic acid, for this reason, the utility model provides a sample is preserved and is handled card box.
In order to achieve the above object, the utility model provides a following technical scheme:
a sample retention process cartridge, comprising:
the first clamping box is used for containing a sample, and a first box cover for closing the first clamping box is detachably arranged on the first clamping box;
a second cartridge detachably provided on the first cartridge, the second cartridge storing a processing liquid; and
the opener is arranged at the junction of the first clamping box and the second clamping box and can puncture the junction and conduct the first clamping box and the second clamping box.
In one embodiment of the present invention, the first card box comprises:
a first case having a first opening and a second opening;
the first box cover is detachably arranged at the first opening; and
the first sealing layer is arranged at the second opening, and a first cavity for containing a sample is defined by the first sealing layer, the first box cover and the first box body.
In one embodiment of the present invention, the second cartridge comprises:
a second container having a third opening;
the second box cover is arranged on the second box body and corresponds to the third opening, the part, provided with the first sealing layer, of the first box body can be arranged on the second box cover, the opener is located in the second box cover, and the opener can scratch the first sealing layer and conduct the first clamping box and the second clamping box under the action of external force.
The utility model discloses in one of them embodiment, the second card box is still including setting up the second sealing layer of third opening, the treatment fluid is sealed the second sealing layer with in the second cavity that the second box body encloses, the mouth gag is simultaneously scratched under the exogenic action first sealing layer with the second sealing layer.
The utility model discloses in one of them embodiment, the first terminal surface of second lid is provided with and is used for the installation the first recess of first box body, the second terminal surface of second lid is provided with and is used for the installation the second recess of second box body, the middle part of second lid is provided with the fretwork hole, the mouth gag with the fretwork hole cooperatees to switch on through rotating or sliding first card box with the second card box.
The utility model discloses in one of them embodiment, be provided with on the second lid and hold the guiding hole of mouth gag, mouth gag slidable sets up the guiding hole, just the mouth gag in the slip in-process with the guiding hole closely cooperates, the mouth gag is located the one end of second lid is provided with first barb, the mouth gag exposes the one end of guiding hole is provided with tears the handle.
In one embodiment of the present invention, the opener seals the hollow hole.
The utility model discloses in one of them embodiment, the rotatable setting of mouth gag is in the second lid, just there is a part to expose in the pivot of mouth gag the second lid, the edge of mouth gag is provided with the opening sword, the one end that the second lid is exposed in the pivot is provided with rotatory handle.
In one embodiment of the present invention, the first sealing layer and the second sealing layer are disposable aseptic sealing tinfoil paper.
In one embodiment of the present invention, the first card box is rotatably fitted with the second box cover, the mouth gag is disposed on the inner wall of the second box cover, and the mouth gag has a second barb; be provided with first screens and second screens on the first recess, work as the second card box is located during the first screens, the second barb with first sealing layer contactless, under the exogenic action, first card box by first screens removes during the second screens, the second barb punctures first sealing layer.
In one embodiment of the present invention, the second box body is rotatably fitted with the second box cover, the mouth gag is disposed on the inner wall of the second box cover, and the mouth gag has a third barb; be provided with third screens and fourth screens on the second recess, work as the second card box is located during the third screens, the third barb with the second sealing layer is not contacted, and under the exogenic action, the second box body by the third screens removes during the fourth screens, the third barb punctures the second sealing layer.
In one embodiment of the present invention, the first card box and the second card box are disposed side by side or stacked.
According to the technical scheme, when the card box is used for storing and processing the samples, the first box cover is detached, the extracted samples are placed in the first card box, and the first box cover is covered to enable the samples to be in an isolated state with the outside; when the sample is required to be processed, the first card box is arranged on the second card box, the first card box and the second card box are in a conduction state by moving the opener, and the sample in the first card box enters the second card box and correspondingly reacts with the processing liquid in the second card box. Therefore, in the process, the sample is not in contact with the outside during storage and sample transfer, so that the influence on the extraction quality of the nucleic acid is reduced, and the influence on the interpretation of the nucleic acid detection result is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic front view of a sample storage and processing cartridge according to an embodiment of the present invention;
fig. 2 is a schematic front view of a first card box according to an embodiment of the present invention;
fig. 3 is a schematic front view of a second card box according to an embodiment of the present invention;
fig. 4 is a schematic cross-sectional view of a second cover according to an embodiment of the present invention;
fig. 5 is a schematic view of a matching structure of a second box cover and an opener according to an embodiment of the present invention;
fig. 6 is a schematic view of another matching structure of the second cover and the mouth gag provided by the embodiment of the present invention;
fig. 7 is a schematic view of a matching structure of a second cover and an opener according to an embodiment of the present invention;
FIG. 8 is a schematic top view of the mouth gag of FIG. 7;
fig. 9 is a schematic structural view of the first card box of the embodiment of the present invention in the first position and the second box in the third position;
fig. 10 is a schematic structural view of the first card box in the second position and the second box in the fourth position according to the embodiment of the present invention;
fig. 11 is a schematic structural view of another first card box in the first position and the second box in the third position according to the embodiment of the present invention;
fig. 12 is a schematic structural view of the second cartridge in the second position and the second cartridge in the fourth position according to the embodiment of the present invention.
Wherein 100 is the first card box, 200 is the second card box, 300 is the mouth gag, 101 is the first lid, 102 is the first box body, 103 is the first sealing layer, 201 is the second box body, 202 is the second lid, 203 is the second sealing layer, 301 is the first barb, 302 is tearing the handle, 303 is the opening sword, 304 is rotatory handle, 305 is the second barb, 2021 is the first recess, 2022 is the second recess, 2023 is the fretwork hole, 2024 is the guiding hole.
Detailed Description
The core of the utility model is to provide a sample is preserved and is handled card box to how improve the extraction quality of nucleic acid.
The embodiments described below do not limit the scope of the invention described in the claims. Further, the entire contents of the configurations shown in the following embodiments are not limited to those necessary as a solution of the invention described in the claims.
Referring to fig. 1 to 12, the sample storage and processing cartridge of the present invention includes:
a first cartridge 100 for containing a sample, the first cartridge 100 being detachably provided with a first cover 101 closing the first cartridge 100;
a second cartridge 200 detachably provided on the first cartridge 100, the second cartridge 200 storing a process liquid; and
and the opener 300 is arranged at the interface of the first card box 100 and the second card box 200, and the opener 300 can penetrate the interface and conduct the first card box 100 and the second card box 200.
When the sample storage and processing card box is used, the first box cover 101 is detached, the extracted sample is placed in the first card box 100, and the first box cover 101 is covered to enable the sample to be in an isolated state with the outside; when a sample process is required, the first cartridge 100 is disposed on the second cartridge 200, and the first cartridge 100 and the second cartridge 200 are in a conductive state by moving the opener 300, so that the sample in the first cartridge 100 enters the second cartridge 200 and reacts with the process liquid in the second cartridge 200. Therefore, in the process, the sample is not in contact with the outside during storage and sample transfer, so that the influence on the extraction quality of the nucleic acid is reduced, and the influence on the interpretation of the nucleic acid detection result is reduced.
Note that the first cartridge 100 and the second cartridge 200 are disposed side by side or stacked. Here, the side-by-side arrangement means that the axis of the first cartridge 100 is parallel to the axis of the second cartridge 200; by stacked arrangement, it is meant that the axis of the first cartridge 100 coincides with the axis of the second cartridge 200. No matter set up side by side or the stack setting all is in the utility model discloses a protection scope.
The first cartridge 100 functions to hold a sample, and the first cartridge 100 includes: a first container 102, the first container 102 having a first opening and a second opening; a first cover 101 detachably disposed at the first opening; and the first sealing layer 103 is arranged at the second opening, and a first cavity for containing the sample is enclosed by the first sealing layer 103, the first box cover 101 and the first box body 102.
The first opening and the second opening are arranged at different positions according to the arrangement positions of the first card box 100 and the second card box 200, the second opening is arranged at the junction of the first card box 100 and the second card box 200, and the first opening and the second opening are arranged in a staggered manner. When the first cartridge 100 and the second cartridge 200 are arranged side by side, the second opening is arranged at one side of the first box 102, the first opening is arranged at the other side of the first box 102 or at the top of the first box 102, preferably, the first opening is arranged at the top of the first box 102; when the first cartridge 100 is stacked with the second cartridge 200, the second opening is disposed at the bottom of the first container 102, the first opening is disposed at both sides of the first container 102 or at the top of the first container 102, and preferably, the first opening is disposed at the top of the first container 102.
The second cartridge 200 serves to store the process liquid, and the second cartridge 200 includes: a second case 201, the second case 201 having a third opening; and a second cover 202 disposed on the second case 201 and corresponding to the third opening, wherein the portion of the first case 102 where the first sealing layer 103 is disposed can be disposed on the second cover 202, and the opener 300 is disposed in the second cover 202, and the opener 300 cuts the first sealing layer 103 by external force to conduct the first cartridge 100 and the second cartridge 200.
The position of the third opening is related to the positions of the first and second cartridges 100 and 200, but the third opening is provided at the boundary of the second cartridge 200 and the first cartridge 100. When the first cartridge 100 and the second cartridge 200 are arranged side by side, the third opening is provided at one side of the second box 201; when the first cartridge 100 is disposed to overlap the second cartridge 200, the third opening is disposed at the top of the second case 201.
The first cartridge 100 and the second cartridge 200 are connected by the second cover 202, wherein the first cartridge 100 and the second cover 202 are detachably connected, for example, clamped and screwed, when the first cartridge 100 is installed in the second cover 202, the connection between the first cartridge 100 and the second cover 202 can be ensured, and the sealing property at the connection between the first cartridge 100 and the second cover 202 can be ensured.
The second cover 202 is detachably connected to the second box 201, for example, by clamping, screwing, or non-detachable connection. Regardless of the detachable connection or the non-detachable connection, the sealing performance when the second cover 202 is connected to the second container 201 can be ensured.
Specifically, a first end face of the second box cover 202 is provided with a first groove 2021 for installing the first box body 102, a second end face of the second box cover 202 is provided with a second groove 2022 for installing the second box body 201, a hollow hole 2023 is arranged in the middle of the second box cover 202, and the opener 300 is matched with the hollow hole 2023 and conducts the first card box 100 and the second card box 200 through rotation or sliding.
The opener 300 is disposed on the second cover 202 to facilitate the first sealing layer 103 to be cut open, so as to conduct the first card box 100 and the second card box 200. Wherein the opener 300 cuts the first sealing layer 103 by rotating or sliding to conduct the first cartridge 100 and the second cartridge 200.
When the mouth gag 300 cuts the first sealing layer 103 in a sliding manner, the second box cover 202 is provided with a guide hole 2024 for accommodating the mouth gag 300, the mouth gag 300 is slidably disposed in the guide hole 2024, the mouth gag 300 is tightly fitted with the guide hole 2024 in the sliding process, one end of the mouth gag 300 located on the second box cover 202 is provided with a first barb 301, and one end of the mouth gag 300 exposed out of the guide hole 2024 is provided with a tearing handle 302. When the sample collection box is used, the first box 100 storing a sample is arranged on the first box cover 101, the first barb 301 is abutted to and punctured by the first sealing layer 103, the tearing handle 302 is pulled outwards, the opener 300 slides outwards along the guide hole 2024, finally the first sealing layer 103 is completely scratched, and the sample enters the second box body 201 from the first sealing layer 103 and the hollowed hole 2023.
In the above process, the mouth gag 300 has the function of opening on the one hand, and the mouth gag 300 has the function of sealing the hollow-out hole 2023 on the other hand.
When the mouth gag 300 cuts the first sealing layer 103 in a rotating manner, the mouth gag 300 is rotatably disposed on the second box cover 202, and a part of a rotating shaft of the mouth gag 300 is exposed out of the second box cover 202, an opening blade 303 is disposed at an edge of the mouth gag 300, and a rotating handle 304 is disposed at an end of the rotating shaft exposed out of the second box cover 202. In use, the first cartridge 100 storing the sample is mounted on the first cover 101, the rotating handle 304 is rotated, the mouth gag 300 rotates, when the opening blade 303 on the mouth gag 300 contacts with the first sealing layer 103, the opening blade 303 scratches the first sealing layer 103 completely, and the sample enters the second container 201 from the first sealing layer 103 and the hollowed hole 2023.
In order to conveniently store the processing liquid, the second cartridge 200 further comprises a second sealing layer 203 arranged at the third opening, the processing liquid is sealed in a second cavity defined by the second sealing layer 203 and the second box 201, and the opener 300 simultaneously cuts the first sealing layer 103 and the second sealing layer 203 under the action of external force.
When the mouth gag 300 cuts the first sealing layer 103 and the second sealing layer 203 in a sliding manner, a guide hole 2024 for accommodating the mouth gag 300 is formed in the second box cover 202, the mouth gag 300 is slidably disposed in the guide hole 2024, the mouth gag 300 is tightly fitted with the guide hole 2024 in the sliding process, a first barb 301 is disposed at one end of the mouth gag 300 located in the second box cover 202, wherein a surface corresponding to the first sealing layer 103 and a surface corresponding to the second sealing layer 203 are both provided with the first barb 301, and a tearing handle 302 is disposed at one end of the mouth gag 300 exposed out of the guide hole 2024. When the sample collection box is used, the first box 100 storing a sample is arranged on the first box cover 101, the first barb 301 is abutted to and punctured by the first sealing layer 103, the tearing handle 302 is pulled outwards, the mouth opener 300 slides outwards along the guide hole 2024, finally the first sealing layer 103 and the second sealing layer 203 are all scratched, and the sample enters the second box body 201 from the first sealing layer 103, the hollowed hole 2023 and the second sealing layer 203.
When the mouth gag 300 cuts the first sealing layer 103 and the second sealing layer 203 in a rotating manner, the mouth gag 300 is rotatably arranged on the second box cover 202, a part of a rotating shaft of the mouth gag 300 is exposed out of the second box cover 202, an opening blade 303 is arranged at the edge of the mouth gag 300, and a rotating handle 304 is arranged at one end of the rotating shaft exposed out of the second box cover 202. When the first cartridge 100 storing the sample is used, the first cartridge 100 is mounted on the first box cover 101, the rotating handle 304 is rotated, the mouth gag 300 rotates, when the opening blade 303 on the mouth gag 300 contacts with the first sealing layer 103 and the second sealing layer 203, the opening blade 303 cuts all of the first sealing layer 103 and the second sealing layer 203, and the sample enters the second box body 201 from the first sealing layer 103, the hollowed-out hole 2023 and the second sealing layer 203.
The first sealing layer 103 and the second sealing layer 203 are relatively easily torn, and for example, the first sealing layer 103 and the second sealing layer 203 are disposable aseptic sealing tinfoil paper.
The utility model also discloses another structure for cutting the first sealing layer 103, the first clamping box 100 is rotationally matched with the second box cover 202, the mouth gag 300 is arranged at the inner wall of the second box cover 202, and the mouth gag 300 is provided with a second barb 305; the first groove 2021 is provided with a first detent and a second detent, when the second cartridge 200 is located in the first detent, the second barb 305 is not in contact with the first sealing layer 103, and when the first cartridge 100 moves from the first detent to the second detent under the action of external force, the second barb 305 pierces the first sealing layer 103. When the sample collection box is used, the first card box 100 with the sample stored therein is arranged in the first clamping position of the first box cover 101, external force is continuously applied, the first card box 100 slides into the second clamping position from the first clamping position, the second barb 305 is enabled to be in contact with the first sealing layer 103, the first card box 100 or the second box cover 202 is rotated, the second barb 305 completely punctures the first sealing layer 103, and the sample enters the second box body 201 from the first sealing layer 103 and the hollowed hole 2023.
The utility model also discloses another structure for cutting the second sealing layer 203, the second box body 201 is matched with the second box cover 202 in a rotating way, the mouth gag 300 is arranged at the inner wall of the second box cover 202, and the mouth gag 300 is provided with a third barb; the second groove 2022 is provided with a third locking position and a fourth locking position, when the second cartridge 200 is located in the third locking position, the third barb is not in contact with the second sealing layer 203, and when the second cartridge 201 is moved to the fourth locking position by the third locking position under the action of external force, the second sealing layer 203 is punctured by the third barb. When the second cartridge 200 is used, when the processing liquid is stored in the second cartridge 200, the second cartridge 201 is located at the third position of the second cartridge cover 202, when the second sealing layer 203 needs to be punctured, an external force is applied, so that the second cartridge 201 slides from the third position to the fourth position, the second barb 305 completely punctures the second sealing layer 203, and a sample enters the second cartridge 201 from the first sealing layer 103, the hollow hole 2023 and the second sealing layer 203.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (12)
1. A sample retention process cartridge, comprising:
the first clamping box is used for containing a sample, and a first box cover for closing the first clamping box is detachably arranged on the first clamping box;
a second cartridge detachably provided on the first cartridge, the second cartridge storing a processing liquid; and
the opener is arranged at the junction of the first clamping box and the second clamping box and can puncture the junction and conduct the first clamping box and the second clamping box.
2. The sample retention process cartridge of claim 1, wherein the first cartridge comprises:
a first case having a first opening and a second opening;
the first box cover is detachably arranged at the first opening; and
the first sealing layer is arranged at the second opening, and a first cavity for containing a sample is defined by the first sealing layer, the first box cover and the first box body.
3. The sample retention process cartridge of claim 2, wherein the second cartridge comprises:
a second container having a third opening;
the second box cover is arranged on the second box body and corresponds to the third opening, the part, provided with the first sealing layer, of the first box body can be arranged on the second box cover, the opener is located in the second box cover, and the opener can scratch the first sealing layer and conduct the first clamping box and the second clamping box under the action of external force.
4. The sample retention process cartridge of claim 3, wherein the second cartridge further comprises a second sealing layer disposed at the third opening, the processing fluid being sealed in a second cavity defined by the second sealing layer and the second casing, the opener being configured to simultaneously rupture the first sealing layer and the second sealing layer under an external force.
5. The sample storage and processing cartridge of claim 4, wherein the first end of the second cover is provided with a first groove for mounting the first container, the second end of the second cover is provided with a second groove for mounting the second container, the middle of the second cover is provided with a hollow hole, and the opener is matched with the hollow hole and can be used for conducting the first cartridge and the second cartridge through rotation or sliding.
6. The sample storage and processing cartridge of claim 5, wherein the second cover has a guide hole for receiving the mouth gag, the mouth gag is slidably disposed in the guide hole and is tightly fitted with the guide hole during sliding, the end of the mouth gag located on the second cover has a first barb, and the end of the mouth gag exposed out of the guide hole has a tearing handle.
7. The sample retention process cartridge of claim 6, wherein the opener seals the hollowed out aperture.
8. The sample storage and processing cartridge of claim 5, wherein the mouth gag is rotatably disposed on the second cover, and a part of the rotation shaft of the mouth gag is exposed out of the second cover, and the mouth gag has an opening blade at its edge and a rotation handle at the end of the rotation shaft exposed out of the second cover.
9. The sample retention process cartridge of claim 4, wherein the first sealing layer and the second sealing layer are disposable sterile seal tinfoil.
10. The sample retention process cartridge of claim 5, wherein the first cartridge is rotationally engaged with the second cover, the opener is disposed at an inner wall of the second cover, the opener has a second barb thereon; be provided with first screens and second screens on the first recess, work as the second card box is located during the first screens, the second barb with first sealing layer contactless, under the exogenic action, first card box by first screens removes during the second screens, the second barb punctures first sealing layer.
11. The sample retention process cartridge of claim 10, wherein the mouth gag has a third barb thereon; be provided with third screens and fourth screens on the second recess, work as the second card box is located during the third screens, the third barb with the second sealing layer is not contacted, and under the exogenic action, the second box body by the third screens removes during the fourth screens, the third barb punctures the second sealing layer.
12. The sample retention process cartridge of claim 1, wherein the first cartridge is positioned side-by-side or stacked with the second cartridge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021335958.3U CN213172304U (en) | 2020-07-09 | 2020-07-09 | Sample is preserved and is handled card box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021335958.3U CN213172304U (en) | 2020-07-09 | 2020-07-09 | Sample is preserved and is handled card box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213172304U true CN213172304U (en) | 2021-05-11 |
Family
ID=75792005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021335958.3U Active CN213172304U (en) | 2020-07-09 | 2020-07-09 | Sample is preserved and is handled card box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213172304U (en) |
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2020
- 2020-07-09 CN CN202021335958.3U patent/CN213172304U/en active Active
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