CN213051093U

CN213051093U - Multi-channel automatic liquid-separating bearing device and multi-channel automatic liquid-separating system

Info

Publication number: CN213051093U
Application number: CN202020690064.XU
Authority: CN
Inventors: 范分良; 宋阿琳; 董炜灵
Original assignee: Institute of Agricultural Resources and Regional Planning of CAAS
Current assignee: Institute of Agricultural Resources and Regional Planning of CAAS
Priority date: 2020-04-29
Filing date: 2020-04-29
Publication date: 2021-04-27
Anticipated expiration: 2030-04-29

Abstract

The utility model discloses an automatic branch liquid supporting device of multichannel and automatic branch liquid system of multichannel aims at solving among the prior art when the layering liquid is collected wastes time and energy, unable batch processing, the big problem of sample test error of same batch after the hypervelocity centrifugation. The utility model discloses a multichannel automatic liquid separation supporting device, which comprises a test tube rack and a base arranged under the test tube rack, wherein the lower part of the test tube rack is provided with a guide rail; and a driving unit for driving the guide rail to move is arranged in the base. The utility model discloses an automatic liquid system that divides of multichannel, including separator and branch liquid supporting device. The utility model has simple structure, easy operation and is friendly to the testers; the device can simultaneously separate and collect the layered liquid of a plurality of or even a large number of ultracentrifuge samples, and has good repeatability, high efficiency and small test error of samples in the same batch.

Description

Multi-channel automatic liquid-separating bearing device and multi-channel automatic liquid-separating system

Technical Field

The utility model relates to a centrifugal separation equipment technical field, concretely relates to automatic branch liquid supporting device of multichannel and automatic branch liquid system of multichannel.

Background

Centrifugal separation is a physical separation and analysis technique which utilizes the difference of density, shape and size between different substances and uses a centrifugal force field to separate and extract different particles in suspension, and is widely applied to the fields of biology (biological engineering, biological products and the like), medicine, chemistry, chemical engineering and the like. Centrifuges are machines that utilize centrifugal force to separate components of a liquid from solid particles or a liquid and liquid mixture.

After ultra-high speed centrifugation, the layered liquid needs to be separated and collected in time, and if the retention time is too long, the density gradient formed by centrifugation is reduced, so that the centrifugation is ineffective. In the prior art, a centrifugal tube is fixed on a common iron support by a clamp during layered separation, and then is punctured by a needle, the force is not easy to master during fixing, and the centrifugal tube can loosen, slide down or fall off when being loosened; the liquid in the centrifugal tube is easily extruded due to over-tightness, and centrifugal layering is formed due to interference; and the operator can only separate one tube at a time, one tube takes 10 to 20 minutes, and when the number of samples is large, a large amount of time is required for processing, which causes the density gradient difference between the first tube and the last tube to be large, and increases the test error; when in collection, a single test tube takes time and labor, samples are easy to be confused after collection, and batch processing cannot be carried out, so that the detection repeatability is poor and the error is large.

SUMMERY OF THE UTILITY MODEL

The to-be-solved technical problem of the utility model is to provide an automatic liquid supporting device that divides of multichannel and automatic liquid system that divides of multichannel, the problem that among the prior art the layering liquid is wasted time and energy, unable batch processing, same batch sample test error is big when collecting after the hypervelocity centrifugation.

In order to solve the technical problem, the utility model adopts the following technical scheme:

the multichannel automatic liquid separation supporting device comprises a test tube rack and a base arranged below the test tube rack, wherein a guide rail is arranged at the lower part of the test tube rack; and a driving unit for driving the guide rail to move is arranged in the base.

Preferably, the guide rail is a toothed guide rail, and the driving unit includes a rotating shaft, a gear sleeved outside the rotating shaft, and a motor driving the rotating shaft to rotate.

Preferably, a switch is arranged on the base.

Designing a multi-channel automatic liquid separation system, which comprises a separation device and a liquid separation bearing device, wherein the separation device comprises a bottom plate, a bracket fixed on the bottom plate and a separation unit; the upper part of the bracket is provided with a through hole, and the side surface of the bracket is provided with a fastening screw corresponding to the through hole; the separation unit passes through the through hole and is fixed by the fastening screw;

the separation unit comprises a double-ended solenoid for containing a centrifuge tube; the upper end of the double-head solenoid is in threaded connection with a head seal, and the lower end of the double-head solenoid is in threaded connection with a connecting nut; the lower part of the connecting nut is in threaded connection with a tail seal; and the axial center of the tail seal is connected with a puncture needle in a sliding manner.

The liquid separation receiving device comprises a test tube rack and a base arranged below the test tube rack, and a guide rail is arranged at the lower part of the test tube rack; and a driving unit for driving the guide rail to move is arranged in the base.

Preferably, the upper part of the test tube rack is provided with a plurality of tube placing holes; the tube placing hole is matched with the puncture needle in position.

Compared with the prior art, the utility model has the beneficial technical effects of:

1. the utility model has the advantages of simple structure, easy operation is friendly to testing personnel.

2. The utility model discloses can handle the separation and the collection of the layering liquid of a plurality of ultracentrifuge samples even a large amount of simultaneously, good reproducibility, efficient, sample test error is little with batch.

Drawings

Fig. 1 is one of schematic three-dimensional structures of a multi-channel automatic liquid separation system.

FIG. 2 is a schematic perspective view of a multi-channel ultra-high speed centrifugal stratified liquid separation apparatus.

Fig. 3 is a schematic perspective view of the separation unit.

Fig. 4 is an exploded perspective view of the separation unit.

Fig. 5 is a schematic perspective view of the multi-channel automatic liquid-separating receiving device.

Fig. 6 is a schematic view of the internal structure of the multi-channel automatic liquid-separating receiving device.

Fig. 7 is a schematic view of the interface structure of the multi-channel automatic liquid separation receiving device (the dotted line indicates the internal structure).

Fig. 8 is a schematic view of the structure of the guide rail and the driving unit.

Fig. 9 is a schematic perspective view of a second multi-channel automatic liquid separation system.

In the above figures, 1 is a bottom plate; 2, a bracket, 21, a through hole and 22 are fastening screws; 3 is a separation unit, 31 is a double-end solenoid, 32 is a head seal, 33 is a joining nut, 34 is a tail seal, and 35 is a puncture needle; 4 is a centrifuge tube; 5 is a test tube rack, 51 is a tube placing hole, and 52 is a guide rail; 6 is a base, 61 is a driving unit, 611 is a gear, 612 is a rotating shaft, 613 is a motor, and 62 is a power switch; 7 is a test tube.

Detailed Description

The following embodiments are only intended to illustrate the present invention in detail, and do not limit the scope of the present invention in any way.

The components and structures or unit modules referred to in the following examples are all conventional commercially available products unless otherwise specified.

Example 1: multi-channel automatic liquid distribution system

Referring to fig. 1, the multi-channel automatic liquid separation system comprises a multi-channel ultra-high speed centrifugal layered liquid separation device and a multi-channel automatic liquid separation receiving device;

referring to fig. 2, the multi-channel ultra-high speed centrifugal stratified liquid separation device comprises a bottom plate 1, a door-shaped bracket 2 fixed on the bottom plate 1, and 7 separation units 3; the thickness of the base plate 1 is 10 mm.

The upper part of the door-shaped bracket 2 is provided with a plurality of through holes 21; a fastening screw 22 is arranged at the position of the side surface of the door-shaped bracket 2 corresponding to the position of the through hole 21; the separation unit 3 is fixed on the bracket 2 through the through hole 21 by a fastening screw 22; the height of the holder 2 is 350 mm.

Referring to figures 3 and 4, the separation unit 3 comprises a double-ended coil 31 into which the centrifuge tube 4 is placed in use; the upper end of the double-ended solenoid 31 is in threaded connection with a head seal 32 with a hole, and the size of the hole is matched with the tip of the centrifugal tube 4; the lower end of the double-end screwed pipe 31 is connected with a connecting nut 33 in a threaded manner; the lower part of the engaging nut 33 is in threaded connection with a tail seal 34, as shown in fig. 5, the upper part of the tail seal 34 can support the bottom of the centrifuge tube 4 after the separation unit 3 is assembled; the tail seal 34 is connected with a puncture needle 35 in a sliding way at the axial center, and the puncture needle 35 is pushed upwards to puncture the bottom of the centrifugal tube 4 during separation. When the separation unit 3 is assembled, a gasket is arranged between the double-ended solenoid 31 and the tail seal 34.

Referring to fig. 5-7, the multichannel automatic liquid separation receiving device comprises a test tube rack 5 and a base 6; the upper part of the test tube rack 5 is provided with a plurality of tube placing holes 51 (used for placing test tubes 7), and the lower part is provided with a tooth-shaped guide rail 52; the position of the tube placing hole 51 is matched with the position of the puncture needle 35 of the separation unit 3; a driving unit 61 is arranged in the base 6, the driving unit 62 comprises a gear 611, a rotating shaft 612 is arranged at the center of the gear 611, and the rotating shaft 612 is provided with a motor 613 for driving the rotating shaft to rotate; the base is provided with a power switch 62.

Referring to fig. 8, the gear 611 matches with the teeth of the toothed rail 52, and the rotation shaft 612 rotates the gear 611 to drive the rail 52 to transmit. The rotating speed and frequency of the rotating shaft 612 are matched with the liquid separation of the separation unit 3.

Example 2: multi-channel automatic liquid distribution system

The difference from the embodiment 1 is that:

referring to fig. 9, the multi-channel ultra-high speed centrifugal stratified liquid separation device of the multi-channel automatic liquid separation system comprises a bottom plate 1, an H-shaped bracket 2 fixed on the floor, and 13 separation units 3.

The operation and use method of the multi-channel automatic liquid separation system comprises the following steps:

after ultracentrifugation, during layering liquid separation, head seal 32 is screwed out, centrifuge tube 4 containing each sample is respectively placed into double-end solenoid 31, head seal 32 is rotationally fixed on double-end solenoid 31, the interference layering caused by clamp clamping can be effectively avoided, puncture needle 35 is pushed upwards to puncture centrifuge tube 4 bottom, liquid flows into test tube 7 on the multichannel automatic liquid separation bearing device, switch 62 is opened, motor 613 drives rotating shaft 612 to drive gear 611 to rotate, guide rail 52 drives test tube rack 5 to move, it is reached to make test tube 7 on test tube rack 5 bear the liquid of different layering, so that the liquid of different layering in each centrifuge tube 4 of the same batch can be collected uniformly.

While the present invention has been described in detail with reference to the drawings and the embodiments, it will be understood by those skilled in the art that various changes in the specific parameters of the embodiments or equivalent substitutions of parts and structures may be made without departing from the spirit of the present invention, thereby forming a plurality of specific embodiments which are common variations of the present invention and not described in detail herein.

Claims

1. A multi-channel automatic liquid separation supporting device comprises a test tube rack and a base arranged below the test tube rack, and is characterized in that a guide rail is arranged at the lower part of the test tube rack; and a driving unit for driving the guide rail to move is arranged in the base.

2. The multi-channel automatic liquid distribution receiving device according to claim 1, wherein the guide rail is a toothed guide rail, and the driving unit comprises a rotating shaft, a gear sleeved outside the rotating shaft, and a motor for driving the rotating shaft to rotate.

3. The multi-channel automatic liquid distribution receiving device according to claim 1, wherein a switch is provided on the base.

4. A multi-channel automatic liquid-separating system, comprising a separating device and a liquid-separating receiving device according to any one of claims 1-3, wherein the separating device comprises a bottom plate, a bracket fixed on the bottom plate and a separating unit; the upper part of the bracket is provided with a through hole, and the side surface of the bracket is provided with a fastening screw corresponding to the through hole; the separation unit passes through the through hole and is fixed by the fastening screw;

5. The multi-channel automatic liquid separation system according to claim 4, wherein the liquid separation receiving device comprises a test tube rack and a base arranged below the test tube rack, and a guide rail is arranged at the lower part of the test tube rack; and a driving unit for driving the guide rail to move is arranged in the base.

6. The multi-channel automatic liquid distribution system according to claim 4, wherein the upper part of the test tube rack is provided with a plurality of tube placing holes; the tube placing hole is matched with the puncture needle in position.

7. The multi-channel automatic liquid distribution system according to claim 5, wherein the guide rail is a toothed guide rail, and the driving unit comprises a rotating shaft, a gear sleeved outside the rotating shaft, and a motor for driving the rotating shaft to rotate.