CN213012905U

CN213012905U - A culture detection case for stem cell

Info

Publication number: CN213012905U
Application number: CN202021573466.8U
Authority: CN
Inventors: 湛振键; 齐国光; 刘世豪
Original assignee: Haikou Health Island Biotechnology Co ltd
Current assignee: Haikou Health Island Biotechnology Co ltd
Priority date: 2020-07-31
Filing date: 2020-07-31
Publication date: 2021-04-20
Anticipated expiration: 2030-07-31

Abstract

The utility model provides a culture detection case for stem cell, including a hollow cylindricality barrel, cylindricality barrel bottom is equipped with the control box, be equipped with industrial computer, communication module in the control box, be equipped with a plurality of layers of culture rack on the inside wall of cylindricality barrel, every layer of culture rack includes that a plurality of encircles the cultivation position that the inside wall set up, has all placed the culture dish on every cultivation position, and cylindricality barrel axle center department is equipped with rotary mechanism, the last elevating system that is provided with of rotary mechanism, last image acquisition device and the fixture of being provided with of elevating system, image acquisition device is used for gathering the culture dish image, fixture is used for the centre gripping to remove the culture dish, and the passageway has been seted up to cylindricality barrel side, communication module, image acquisition device are connected with the industrial computer electricity respectively. The device occupies a small area, and can realize batch culture and detection of stem cells in a stable environment.

Description

A culture detection case for stem cell

Technical Field

The utility model relates to a cell culture technical field especially relates to a culture detection case for stem cell.

Background

The stem cells are cells with unlimited or immortal self-renewal capacity, can generate at least one type of highly differentiated progeny cells, and have extremely wide application prospects in the fields of cell repair of life sciences, developmental biology, pharmacology and the like. At present, stem cells are usually cultured in an incubator, and when the stem cells need to be detected and observed, a culture dish needs to be frequently taken out and put in, but the problem that the stem cells are easily inactivated due to frequent changes of the external environment is also caused.

SUMMERY OF THE UTILITY MODEL

Accordingly, it is an object of the present invention to provide a culture test kit for stem cells, which overcomes or at least partially solves the above-mentioned problems of the prior art culture devices for stem cells.

The utility model discloses the technical scheme who adopts as follows:

the utility model provides a cultivation detection case for stem cell, includes a hollow cylindricality barrel, cylindricality barrel bottom is equipped with the control box, be equipped with industrial computer, communication module in the control box, be equipped with a plurality of layers on the inside wall of cylindricality barrel and cultivate the frame, every layer of cultivation frame includes that a plurality of encircles the cultivation position that the inside wall set up, has all placed the culture dish on every cultivation position, and cylindricality barrel axle center department is equipped with rotary mechanism, the last elevating system that is provided with of rotary mechanism, last image acquisition device and the fixture of being provided with of elevating system, image acquisition device is used for gathering the culture dish image, fixture is used for the centre gripping to remove the culture dish, and the passageway has been seted up to cylindricality barrel side, communication module, image acquisition device are connected with.

Further, rotary mechanism is electronic revolving stage, elevating system includes the push rod motor, the push rod motor sets up on electronic revolving stage's rotating part, electronic revolving stage, push rod motor are connected with the industrial computer electricity respectively.

Further, the image acquisition device comprises a connecting rod and a shell, one end of the connecting rod is connected to the side face of a push rod of the push rod motor, the other end of the connecting rod is connected with the shell, an opening is formed in the bottom of the shell, a camera and an amplifying objective lens group are sequentially arranged in the opening from top to bottom, and the camera is electrically connected with the industrial personal computer.

Furthermore, fixture includes electronic jar and electronic holder, electronic jar is fixed to be set up in the push rod side of push rod motor, electronic holder is connected with the active cell of electronic jar, electronic holder are connected with the industrial computer electricity respectively.

Furthermore, the surface of the cylindrical barrel is provided with a display screen, a key panel and a fingerprint identification device, and the display screen, the key panel and the fingerprint identification device are respectively electrically connected with an industrial personal computer.

Furthermore, a temperature and humidity sensor is arranged in the cylindrical barrel and electrically connected with the industrial personal computer.

Furthermore, a sealing door is arranged at the passage, an electric control lock is arranged on the sealing door, and the electric control lock is electrically connected with an industrial personal computer.

Compared with the prior art, the beneficial effects of the utility model are that:

the utility model provides a culture and detection box for stem cells, wherein a multi-layer culture rack is arranged around the inner side wall of a cylindrical barrel body of the culture and detection box for placing culture dishes for culturing stem cells, a rotating mechanism and a lifting mechanism are arranged at the axle center of the cylindrical barrel body, under the control of the industrial personal computer, the lifting mechanism can drive the image acquisition device and the clamping mechanism to lift above the corresponding culture dish, the rotating mechanism drives the lifting mechanism to rotate, the image acquisition device can rotate to the position right above the culture dish to acquire the stem cell image and send the stem cell image to the industrial personal computer, the industrial personal computer sends the stem cell image to the upper computer through the communication module to realize culture detection, in addition, the culture dish can be clamped and conveyed to the channel by the clamping mechanism to be processed by workers, the device occupies a small area, and batch culture and detection of stem cells in a stable environment can be realized.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only preferred embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without inventive work.

FIG. 1 is a schematic view of the overall structure of a culture and detection box according to an embodiment of the present invention.

FIG. 2 is a schematic cross-sectional top view of a culture detection box according to an embodiment of the present invention.

Fig. 3 is a schematic view of a partial structure of an image capturing device and a clamping mechanism according to an embodiment of the present invention.

FIG. 4 is a schematic view of the front structure of the culture and detection box provided by the second embodiment of the present invention.

FIG. 5 is a schematic diagram of the circuit principle of the culture detection box provided by the second embodiment of the present invention.

In the figure, 1 is a cylindrical barrel, 2 is a control box, 21 is an industrial personal computer, 22 is a communication module, 3 is a culture dish, 4 is a rotating mechanism, 5 is a lifting mechanism, 6 is an image acquisition device, 61 is a connecting rod, 62 is a shell, 63 is a camera, 64 is an amplifying objective lens group, 7 is a clamping mechanism, 71 is an electric cylinder, 72 is an electric clamp holder, 8 is a channel, 81 is a sealing door, 82 is an electric control lock, 9 is a display screen, 10 is a key panel, 11 is a fingerprint identification device, and 12 is a temperature and humidity sensor.

Detailed Description

The principles and features of the present invention are described below in conjunction with the following drawings, the illustrated embodiments are provided to explain the present invention and not to limit the scope of the invention.

Example one

Referring to fig. 1 and 2, the present embodiment provides a culture detection box for stem cells, the culture detection box includes a hollow cylindrical barrel 1, a control box 2 is disposed at the bottom of the cylindrical barrel 1, and an industrial personal computer 21 and a communication module 22 are disposed in the control box 2. Be equipped with a plurality of layers of cultivation frame on the inside wall of cylindricality barrel 1, every layer of cultivation frame includes that a plurality of encircles the cultivation position that the inside wall set up, all places culture dish 3 on every cultivation position. The axial center of the cylindrical barrel 1 is provided with a rotating mechanism 4, the rotating mechanism 4 is provided with a lifting mechanism 5, and the lifting mechanism 5 is provided with an image acquisition device 6 and a clamping mechanism 7. The side surface of the cylindrical barrel 1 is provided with a channel 8.

Specifically, rotary mechanism 4 is electric rotary table, elevating system 5 includes the push rod motor, the push rod motor sets up on electric rotary table's rotating part for electric rotary table can drive the push rod motor and use 1 axial lead of cylindricality barrel to rotate as the axle, electric rotary table, push rod motor are connected with industrial computer 21 electricity respectively.

As shown in fig. 3, the image capturing device 6 is used to capture an image of a culture dish. As an example, the image capturing device 6 includes a connecting rod 61 and a housing 62, one end of the connecting rod 61 is connected to the side of the push rod motor, the other end is fixedly connected to the housing 62, an opening is arranged at the bottom of the housing 62, a camera 63 and an amplifying objective lens group 64 are sequentially arranged in the opening from top to bottom, and the camera 63 is electrically connected to the industrial personal computer 21.

The clamping mechanism 7 is used for clamping the movable culture dish 3. As an example, the clamping mechanism includes an electric cylinder 71 and an electric clamp 72, the electric cylinder 71 is fixedly disposed on the push rod side of the push rod motor, the electric clamp 72 is connected with a mover of the electric cylinder 71, and a clamping portion of the electric clamp 72 faces the side wall direction of the cylindrical barrel 1, so that the electric cylinder 71 can drive the electric clamp 72 to move back and forth in the horizontal direction, and the electric cylinder 71 and the electric clamp 72 are respectively electrically connected with the industrial personal computer 21.

In the above embodiment, the electric rotating platform, the push rod motor, the camera and the industrial personal computer may be of known types of existing equipment on the market. The communication module can adopt a WiFi module or a routing device, the electric holder can adopt an RG2/RG6 electric cooperation holder, the magnifying objective group consists of a plurality of lenses, and the objective lens of a conventional microscope can be adopted.

In this embodiment, when the stem cell culture condition needs to be detected, the industrial personal computer 21 controls the lifting mechanism 5 to lift the image acquisition device 6 to the upper side of each culture layer, and then controls the rotating mechanism 4 to drive the lifting mechanism 5 to rotate, so that the image acquisition device 6 rotates to the position right above the culture position, the camera 63 acquires the amplified image of the stem cells in the culture dish through the amplification objective lens group 64 and transmits the amplified image to the industrial personal computer 21, and the industrial personal computer 21 can transmit image data to an upper computer through the communication module 22 for processing, wherein the upper computer can be a computer or a server. Specifically, in order to prevent the culture sites above and below the image capturing device 6 from blocking the lifting thereof, a certain interval is provided between two adjacent culture sites of each culture layer, so that the image capturing device 6 can be lifted or lowered from the interval.

When a culture dish needs to be taken out, based on a similar principle, the industrial personal computer 21 firstly controls the lifting mechanism 5 to lift or lower the clamping mechanism 7 to a corresponding culture layer, then controls the rotating mechanism 4 to drive the lifting mechanism 5 to rotate, so that the electric clamp 72 is positioned right in front of the corresponding culture dish 3, the electric cylinder 71 drives the electric clamp 72 to move towards the culture dish 3, after the electric clamp 72 clamps the culture dish 3, the electric cylinder 71 drives the electric clamp 72 to move towards the axis direction of the cylindrical barrel 1, so that the culture dish 3 is taken out of a culture position, and the electric clamp 72 is moved to the channel 8 on the side surface of the cylindrical barrel 1 under the driving of the lifting mechanism 5 and the rotating mechanism 4, and a worker can take out the culture dish 3 from the channel 8. Based on the same principle, the worker can also place the culture dish 3 on the electric clamper 72 at the channel 8, and place the culture dish on the culture position through the cooperation of the rotating mechanism, the lifting mechanism and the clamping mechanism.

The device can cultivate stem cells in batches through setting up the multilayer and cultivate the layer to automatic realization is detected stem cell's cultivation, and area is little, has higher practical value.

Example two

On the basis of the foregoing embodiment, the present embodiment differs from the foregoing embodiment in that:

as shown in fig. 4 and 5, the outer surface of the cylindrical barrel 1 is further provided with a display screen 9, a key panel 10 and a fingerprint identification device 11, and the display screen 9, the key panel 10 and the fingerprint identification device 11 are respectively electrically connected with an industrial personal computer 21.

As an example, a temperature and humidity sensor 12 is further disposed in the cylindrical barrel 1 and used for collecting temperature and humidity data inside the cylindrical barrel 1, and the temperature and humidity sensor 12 is electrically connected with the industrial personal computer 21 so as to send the temperature and humidity data to the industrial personal computer 21.

In addition, 8 departments of passageway are equipped with sealing door 81, sealing door 81 is connected with 8 opening parts of passageway hinges, be equipped with electric control lock 82 on the sealing door 81, electric control lock 82 is connected with industrial computer 21 electricity.

In this embodiment, a user may input a control instruction through the key panel 10 to control the image acquisition device 6 to acquire stem cell images in the corresponding culture dish 3, and the industrial personal computer 21 may control the display screen 9 to display the corresponding images. In addition, when a user inputs a control instruction for taking out or putting in the culture dish 3, the user needs to perform identity authentication through the fingerprint identification device 11, and only after the identity authentication is passed, the industrial personal computer 21 executes a corresponding control instruction and controls the electric control lock 82 to unlock the sealing door 81, so that the use safety of stem cells is guaranteed.

The above description is only for the preferred embodiment of the present invention, and is not intended to limit the present invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included within the protection scope of the present invention.

Claims

1. The utility model provides a cultivation detection case for stem cell, a serial communication port, includes a hollow cylindricality barrel, cylindricality barrel bottom is equipped with the control box, be equipped with industrial computer, communication module in the control box, be equipped with a plurality of layers of culture rack on the inside wall of cylindricality barrel, every layer of culture rack includes that a plurality of encircles the cultivation position that the inside wall set up, has all placed the culture dish on every cultivation position, and cylindricality barrel axle center department is equipped with rotary mechanism, the last elevating system that is provided with of rotary mechanism, last image acquisition device and the fixture of being provided with of elevating system, image acquisition device is used for gathering the culture dish image, fixture is used for the centre gripping to remove the culture dish, and the passageway has been seted up to cylindricality barrel side, communication module, image acquisition device are connected with.

2. The culture detection box for stem cells according to claim 1, wherein the rotating mechanism is an electric rotating table, the lifting mechanism comprises a push rod motor, the push rod motor is arranged on a rotating part of the electric rotating table, and the electric rotating table and the push rod motor are respectively electrically connected with an industrial personal computer.

3. The culture detection box for stem cells according to claim 2, wherein the image acquisition device comprises a connecting rod and a housing, one end of the connecting rod is connected to the side face of a push rod of the push rod motor, the other end of the connecting rod is connected with the housing, an opening is formed in the bottom of the housing, a camera and an amplifying objective lens group are sequentially arranged in the opening from top to bottom, and the camera is electrically connected with an industrial personal computer.

4. The culture and detection box for stem cells according to claim 2, wherein the clamping mechanism comprises an electric cylinder and an electric clamper, the electric cylinder is fixedly arranged on the side surface of the push rod motor, the electric clamper is connected with a rotor of the electric cylinder, and the electric cylinder and the electric clamper are respectively and electrically connected with an industrial personal computer.

5. The culture detection box for stem cells according to claim 1, wherein a display screen, a key panel and a fingerprint identification device are arranged on the outer surface of the cylindrical barrel, and the display screen, the key panel and the fingerprint identification device are respectively and electrically connected with an industrial personal computer.

6. The culture detection box for stem cells according to claim 1, wherein a temperature and humidity sensor is arranged in the cylindrical barrel and electrically connected with an industrial personal computer.

7. The culture detection box for stem cells according to claim 1, wherein a sealing door is arranged at the passage, an electric control lock is arranged on the sealing door, and the electric control lock is electrically connected with an industrial personal computer.