CN212999976U - Metronidazole crystallization reaction kettle - Google Patents

Metronidazole crystallization reaction kettle Download PDF

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Publication number
CN212999976U
CN212999976U CN202021407794.0U CN202021407794U CN212999976U CN 212999976 U CN212999976 U CN 212999976U CN 202021407794 U CN202021407794 U CN 202021407794U CN 212999976 U CN212999976 U CN 212999976U
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fixedly connected
gear
crushing
metronidazole
driving shaft
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CN202021407794.0U
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徐洪斌
徐锐
李敏
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Huanggang Yinhe Aarti Pharmaceutical Co ltd
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Huanggang Yinhe Aarti Pharmaceutical Co ltd
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Abstract

The utility model discloses a metronidazole crystallization reation kettle, including the supporting legs, the cauldron body and controller, the inside of the cauldron body is provided with the reaction chamber, the both sides fixedly connected with supporting legs of the bottom of the cauldron body, one side fixedly connected with controller of the cauldron body, the top of the opposite side of the cauldron body is provided with the feed inlet. The utility model discloses a be provided with driving motor, first gear, the second gear, the drive shaft, stirring vane, fixed slot and fixed slot, equipment during operation, start driving motor, driving motor's output passes through the shaft coupling and drives first gear revolve, the gear revolve that evenly sets up on the first gear, drive the drive shaft rotation with the gear engagement on the second gear, the stirring vane of the outside both sides of drive shaft then begins the upset stirring, fix in the fixed slot because of the continuous vibration of the rivers impact that receives the reactant, the oscillation effect has been increased, the reaction efficiency is improved.

Description

Metronidazole crystallization reaction kettle
Technical Field
The utility model relates to a metronidazole preparation technical field specifically is a metronidazole crystallization reation kettle.
Background
Metronidazole is a chemical substance with white to slightly yellow appearance, can be prepared into crystals through chemical reaction, is usually used for preventing and treating diseases such as oral infection, digestive tract infection and the like, is generally prepared by most medicines, a crystallization reaction kettle cannot be separated during metronidazole preparation, and the design and the manufacture of the metronidazole crystallization reaction kettle are more and more highly mechanized along with the development of medicine manufacturing technology.
In the process of implementing the present invention, the inventor finds that at least the following problems exist in the prior art and are not solved:
(1) the traditional metronidazole crystallization reaction kettle has low stirring efficiency, and the reaction efficiency is influenced;
(2) the traditional metronidazole crystallization reaction kettle does not have a drying function and is easy to be contaminated by impurities;
(3) the crystallization particles prepared by the traditional metronidazole crystallization reaction kettle are not uniform, and the process flow is complicated.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a metronidazole crystallization reation kettle to provide in solving above-mentioned background art and stir inefficiency, do not possess stoving function and the inhomogeneous problem of crystalline grain.
In order to achieve the above object, the utility model provides a following technical scheme: a metronidazole crystallization reaction kettle comprises supporting legs, a kettle body and a controller, wherein a reaction cavity is arranged in the kettle body, the supporting legs are fixedly connected to two sides of the bottom end of the kettle body, the controller is fixedly connected to one side of the kettle body, a feed inlet is arranged at the top end of the other side of the kettle body, the feed inlet is communicated with the interior of the reaction cavity, a discharge outlet is arranged at the bottom end of the kettle body and communicated with the bottom end of the reaction cavity, a shell is fixedly connected to one side of the top end of the kettle body, a drying mechanism is fixedly connected to the other side of the top end of the kettle body, a driving motor is fixedly connected to the interior of the shell, a first gear is fixedly connected to the output end of the driving motor through a coupler, a driving shaft is vertically connected to the interior of the reaction cavity in a penetrating manner, a rotary joint is fixedly connected to the, the bottom fixedly connected with crushing mechanism of drive shaft, the outside both sides fixedly connected with rabbling mechanism of drive shaft.
Preferably, the first gear and the second gear have the same radius, and the first gear is in meshed connection with the second gear.
Preferably, a fan, an air box, a filter screen and an air guide pipe are sequentially arranged in the drying mechanism, the air box is fixed on one side of the top of the reaction cavity, the fan is fixedly connected to one side of the air box, the filter screen is vertically and fixedly connected to the inside of the air box, the air guide pipe is fixedly connected to the other side of the air box, the air guide pipe is communicated with the inside of the shell, and the bottom end of the air guide pipe is communicated with the driving shaft through a rotary joint.
Preferably, stirring vane, fixed slot, spring and gas pocket have been set gradually to rabbling mechanism's inside, stirring vane sets up in the outside both sides of drive shaft, stirring vane's both ends evenly are provided with fixed slot and gas pocket respectively, the inside of fixed slot transversely runs through and is connected with the spring.
Preferably, the stirring blades are provided with two groups in the stirring mechanism, the fixing grooves are symmetrical about the center line of the driving shaft, the stirring mechanism is provided with two groups outside the driving shaft, and the stirring mechanisms are communicated with the driving shaft.
Preferably, the inside of crushing mechanism has set gradually threaded sleeve, broken pole, broken blade and broken head, the top of threaded sleeve and the bottom fixed connection of drive shaft, the bottom fixedly connected with of threaded sleeve breaks the pole, the outside both sides of breaking the pole evenly are provided with broken blade, the bottom fixedly connected with of breaking the pole breaks the head.
Compared with the prior art, the beneficial effects of the utility model are that: the metronidazole crystallization reaction kettle not only realizes the improvement of reaction efficiency and the increase of drying function, but also realizes the uniform crushing of crystalline particles;
(1) the device is provided with a reaction cavity, a rotary joint, a fan, an air box, a filter screen, an air guide pipe, a driving shaft and a stirring mechanism, wherein after the reaction in the reaction cavity is finished, crystals are deposited at the bottom of the reaction cavity, the fan is started at the moment, hot air enters the air box, is filtered by the filter screen and enters the air guide pipe, the air guide pipe is communicated with and communicated with the driving shaft through the rotary joint, the hot air is sent into the stirring mechanism through the air guide pipe and then enters the reaction cavity through an air hole formed in the stirring mechanism, the crystals at the bottom of the reaction cavity are dried, residual solution is still left on crystal particles obtained after the reaction is finished, and the adhesion of impurities;
(2) by arranging the driving motor, the first gear, the second gear, the driving shaft, the stirring blades, the fixing grooves and the fixing grooves, when the equipment works, the driving motor is started, the output end of the driving motor drives the first gear to rotate through the coupler, the gears uniformly arranged on the first gear rotate and are meshed with the gears on the second gear to drive the driving shaft to rotate, the stirring blades on two sides outside the driving shaft start to turn over and stir, and the fixing grooves fixed in the fixing grooves continuously vibrate due to the impact of water flow of reactants, so that the oscillation effect is increased, and the reaction efficiency is improved;
(3) through being provided with the reaction chamber, driving motor, the drive shaft, broken mechanism, the thread bush, broken pole, broken blade, broken head and discharge gate, after thoroughly drying the junction crystal, restart driving motor, rotate as the drive shaft, fixed connection rotates thereupon at the broken mechanism of drive shaft bottom, the broken pole of fixed connection on the thread bush rotates, drive broken blade and broken head and rotate, broken blade is broken to the crystal body that the granule size is different with broken head, after obtaining even granule, open the discharge gate, the crystal body of deposit bottom the reaction chamber evenly flows under broken mechanism's rotation effect, realized like this that the junction crystal is broken, also make things convenient for even ejection of compact.
Drawings
Fig. 1 is a schematic front view of a cross-sectional structure of the present invention;
FIG. 2 is a schematic view of the front cross-section structure of the drying mechanism of the present invention;
FIG. 3 is a side view, cross-sectional structural diagram of the spring of the present invention;
FIG. 4 is a schematic side view of the cross-sectional structure of the stirring mechanism of the present invention;
fig. 5 is a schematic side view of the crushing mechanism of the present invention.
In the figure: 1. supporting legs; 2. a kettle body; 3. a reaction chamber; 4. a feed inlet; 5. a drive motor; 6. a housing; 7. a first gear; 8. a rotary joint; 9. a drying mechanism; 901. a fan; 902. an air box; 903. filtering with a screen; 904. an air guide pipe; 10. a second gear; 11. a drive shaft; 12. a stirring mechanism; 1201. a stirring blade; 1202. fixing grooves; 1203. a spring; 1204. air holes; 13. a controller; 14. a crushing mechanism; 1401. a threaded sleeve; 1402. a breaking bar; 1403. crushing the blade; 1404. a crushing head; 15. and (4) a discharge port.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides an embodiment: a metronidazole crystallization reaction kettle comprises supporting legs 1, a kettle body 2 and a controller 13, wherein a reaction cavity 3 is arranged inside the kettle body 2, the supporting legs 1 are fixedly connected to two sides of the bottom end of the kettle body 2, the controller 13 is fixedly connected to one side of the kettle body 2, a feed inlet 4 is arranged at the top end of the other side of the kettle body 2, the feed inlet 4 is communicated with the inside of the reaction cavity 3, a discharge outlet 15 is arranged at the bottom end of the kettle body 2, the discharge outlet 15 is communicated with the bottom end of the reaction cavity 3, a shell 6 is fixedly connected to one side of the top end of the kettle body 2, and a drying mechanism 9 is fixedly connected to the other side of;
a fan 901, an air box 902, a filter screen 903 and an air guide pipe 904 are sequentially arranged in the drying mechanism 9, the air box 902 is fixed on one side of the top of the reaction cavity 3, the fan 901 is fixedly connected to one side of the air box 902, the model of the fan 901 can be TA12025, the filter screen 903 is vertically and fixedly connected to the inside of the air box 902, the air guide pipe 904 is fixedly connected to the other side of the air box 902, the air guide pipe 904 is communicated with the inside of the shell 6, and the bottom end of the air guide pipe 904 is communicated with the driving shaft 11 through a rotary;
specifically, as shown in fig. 1 and 2, when the mechanism is used, after the reaction inside the reaction chamber 3 is finished, crystals are deposited at the bottom of the reaction chamber 3, at this time, the fan 901 is started, hot air enters the bellows 902 and is filtered by the filter screen 903 and enters the air guide pipe 904, the air guide pipe 904 is communicated with the driving shaft 11 through the rotary joint 8 and is communicated with the driving shaft, the hot air is sent into the stirring mechanism 12 through the air guide pipe 904 and then enters the reaction chamber 3 through the air hole 1204 arranged on the stirring mechanism 12, and the crystals at the bottom of the reaction chamber 3 are dried, so that residual solution is still left on crystal particles obtained after the reaction is finished, and the crystal can be ensured to reduce the attachment of impurities through drying;
a driving motor 5 is fixedly connected inside the shell 6, the type of the driving motor 5 can be Y90S-2, and the output end of the driving motor 5 is fixedly connected with a first gear 7 through a coupler;
the radiuses of the first gear 7 and the second gear 10 are the same, and the first gear 7 is meshed with the second gear 10;
a driving shaft 11 vertically penetrates through the interior of the reaction cavity 3, the top end of the driving shaft 11 is fixedly connected with a rotary joint 8, the top end of the exterior of the driving shaft 11 is fixedly connected with a second gear 10, and the bottom end of the driving shaft 11 is fixedly connected with a crushing mechanism 14;
the crushing mechanism 14 is internally provided with a threaded sleeve 1401, a crushing rod 1402, crushing blades 1403 and a crushing head 1404 in sequence, the top end of the threaded sleeve 1401 is fixedly connected with the bottom end of the driving shaft 11, the bottom end of the threaded sleeve 1401 is fixedly connected with the crushing rod 1402, the crushing blades 1403 are uniformly arranged on two sides of the outer part of the crushing rod 1402, and the bottom end of the crushing rod 1402 is fixedly connected with the crushing head 1404;
specifically, as shown in fig. 1 and 5, when the mechanism is used, after crystals are thoroughly dried, the driving motor 5 is restarted, when the driving shaft 11 rotates, the crushing mechanism 14 fixedly connected to the bottom end of the driving shaft 11 rotates along with the driving shaft, the crushing rod 1402 fixedly connected to the threaded sleeve 1401 rotates to drive the crushing blade 1403 and the crushing head 1404 to rotate, crystals with different particle sizes are crushed by the crushing blade 1403 and the crushing head 1404, uniform particles are obtained, the discharge hole 15 is opened, and the crystals deposited at the bottom of the reaction chamber 3 uniformly flow out under the rotating action of the crushing mechanism 14, so that the crystals are crushed and the uniform discharge is facilitated;
the two sides of the outside of the driving shaft 11 are fixedly connected with stirring mechanisms 12;
the stirring mechanism 12 is internally provided with a stirring blade 1201, a fixing groove 1202, a spring 1203 and an air hole 1204 in sequence, the stirring blade 1201 is arranged on two sides of the outside of the driving shaft 11, the fixing groove 1202 and the air hole 1204 are respectively and uniformly arranged at two ends of the stirring blade 1201, and the spring 1203 is transversely connected inside the fixing groove 1202 in a penetrating manner;
specifically, as shown in fig. 1, fig. 3 and fig. 4, when the mechanism is used, first, the driving motor 5 is started, the output end of the driving motor 5 drives the first gear 7 to rotate through the coupler, the gears uniformly arranged on the first gear 7 rotate, and are meshed with the gears on the second gear 10 to drive the driving shaft 11 to rotate, the stirring blades 1201 on the two sides outside the driving shaft 11 start to turn over and stir, and the fixing groove 1202 fixed in the fixing groove 1202 continuously vibrates due to the water flow impact of the reactant, so that the oscillation effect is increased, and the reaction efficiency is improved.
The working principle is as follows: the utility model discloses when using, at first, start driving motor 5, driving motor 5's output passes through the shaft coupling and drives first gear 7 and rotate, the gear revolve of evenly setting on first gear 7, drive shaft 11 with the gear engagement on the second gear 10 and rotate, stirring vane 1201 of the outside both sides of drive shaft 11 then begins the upset stirring, fix fixed slot 1202 in fixed slot 1202 because of the continuous vibration of the rivers impact that receives the reactant, increased the oscillation effect, improved reaction efficiency.
Afterwards, after the reaction in the reaction chamber 3 is finished, the crystal is deposited at the bottom of the reaction chamber 3, at this time, the fan 901 is started, hot air enters the bellows 902 and is filtered by the filter screen 903, and enters the air guide pipe 904, the air guide pipe 904 is communicated with the driving shaft 11 through the rotary joint 8 and is communicated with the driving shaft, the hot air is sent to the stirring mechanism 12 through the air guide pipe 904, and then enters the reaction chamber 3 through the air hole 1204 arranged on the stirring mechanism 12, and the crystal at the bottom of the reaction chamber 3 is dried, so that residual solution is still left on the crystal particles obtained after the reaction is finished, and the crystal can be ensured to reduce the attachment of impurities through.
Finally, after the crystalline is thoroughly dried, the driving motor 5 is started again, when the driving shaft 11 rotates, the crushing mechanism 14 fixedly connected to the bottom end of the driving shaft 11 rotates therewith, the crushing rod 1402 fixedly connected to the threaded sleeve 1401 rotates to drive the crushing blade 1403 and the crushing head 1404 to rotate, the crushing blade 1403 and the crushing head 1404 crush crystalline solids with different particle sizes, after uniform particles are obtained, the discharge port 15 is opened, the crystalline solids deposited at the bottom of the reaction chamber 3 uniformly flow out under the rotating action of the crushing mechanism 14, so that the crystalline is crushed, and uniform discharge is facilitated.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims (6)

1. The utility model provides a metronidazole crystallization reation kettle, includes supporting legs (1), the cauldron body (2) and controller (13), its characterized in that: the reaction chamber (3) is arranged in the kettle body (2), supporting legs (1) are fixedly connected to two sides of the bottom end of the kettle body (2), a controller (13) is fixedly connected to one side of the kettle body (2), a feeding port (4) is arranged at the top end of the other side of the kettle body (2), the feeding port (4) is communicated with the inside of the reaction chamber (3), a discharging port (15) is arranged at the bottom end of the kettle body (2), the discharging port (15) is communicated with the bottom end of the reaction chamber (3), a shell (6) is fixedly connected to one side of the top end of the kettle body (2), a drying mechanism (9) is fixedly connected to the other side of the top end of the kettle body (2), a driving motor (5) is fixedly connected to the inside of the shell (6), a first gear (7) is fixedly connected to the output end of the driving motor (5) through a coupler, a driving shaft (11) is vertically connected, the top fixed connection of drive shaft (11) has rotary joint (8), the outside top fixedly connected with second gear (10) of drive shaft (11), the broken mechanism of bottom fixedly connected with (14) of drive shaft (11), the outside both sides fixedly connected with rabbling mechanism (12) of drive shaft (11).
2. The metronidazole crystallization reaction kettle of claim 1, characterized in that: the first gear (7) and the second gear (10) have the same radius, and the first gear (7) is meshed with the second gear (10).
3. The metronidazole crystallization reaction kettle of claim 1, characterized in that: the drying mechanism is characterized in that a fan (901), an air box (902), a filter screen (903) and an air guide pipe (904) are sequentially arranged inside the drying mechanism (9), the air box (902) is fixed on one side of the top of the reaction cavity (3), the fan (901) is fixedly connected to one side of the air box (902), the filter screen (903) is vertically and fixedly connected to the inside of the air box (902), the air guide pipe (904) is fixedly connected to the other side of the air box (902), the air guide pipe (904) is communicated with the inside of the shell (6), and the bottom end of the air guide pipe (904) is communicated with the driving shaft (11) through a rotary joint (8).
4. The metronidazole crystallization reaction kettle of claim 1, characterized in that: stirring vane (1201), fixed slot (1202), spring (1203) and gas pocket (1204) have set gradually in the inside of rabbling mechanism (12), stirring vane (1201) sets up in the outside both sides of drive shaft (11), the both ends of stirring vane (1201) are evenly provided with fixed slot (1202) and gas pocket (1204) respectively, the inside of fixed slot (1202) transversely runs through and is connected with spring (1203).
5. The metronidazole crystallization reaction kettle of claim 4, characterized in that: the stirring blades (1201) are provided with two groups in the stirring mechanism (12), the fixing grooves (1202) are symmetrical about the center line of the driving shaft (11), the stirring mechanism (12) is provided with two groups outside the driving shaft (11), and the stirring mechanism (12) is communicated with the driving shaft (11).
6. The metronidazole crystallization reaction kettle of claim 1, characterized in that: the crushing mechanism is characterized in that a threaded sleeve (1401), a crushing rod (1402), crushing blades (1403) and a crushing head (1404) are sequentially arranged inside the crushing mechanism (14), the top end of the threaded sleeve (1401) is fixedly connected with the bottom end of a driving shaft (11), the bottom end of the threaded sleeve (1401) is fixedly connected with the crushing rod (1402), the crushing blades (1403) are uniformly arranged on two sides of the outer portion of the crushing rod (1402), and the bottom end of the crushing rod (1402) is fixedly connected with the crushing head (1404).
CN202021407794.0U 2020-07-17 2020-07-17 Metronidazole crystallization reaction kettle Active CN212999976U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021407794.0U CN212999976U (en) 2020-07-17 2020-07-17 Metronidazole crystallization reaction kettle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021407794.0U CN212999976U (en) 2020-07-17 2020-07-17 Metronidazole crystallization reaction kettle

Publications (1)

Publication Number Publication Date
CN212999976U true CN212999976U (en) 2021-04-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202021407794.0U Active CN212999976U (en) 2020-07-17 2020-07-17 Metronidazole crystallization reaction kettle

Country Status (1)

Country Link
CN (1) CN212999976U (en)

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