CN212955178U

CN212955178U - Cell and tissue rotary culture equipment

Info

Publication number: CN212955178U
Application number: CN202021488770.2U
Authority: CN
Inventors: 张燕
Original assignee: Suzhou Qianyun Instrument Technology Co ltd
Current assignee: Suzhou Qianyun Instrument Technology Co ltd
Priority date: 2020-07-25
Filing date: 2020-07-25
Publication date: 2021-04-13
Anticipated expiration: 2030-07-25

Abstract

The utility model belongs to the technical field of biological cultivation, especially, be a cell and tissue gyration cultivation equipment, including the gyration seat casing, fixed mounting has driving motor in the gyration seat casing, fixed mounting has two first belt pulleys on driving motor's the output shaft, two axis of rotation are installed in the symmetry rotation on the gyration seat casing, the bottom of axis of rotation extends to in the gyration seat casing, fixed cover is equipped with the second belt pulley in the axis of rotation, the cover is equipped with same belt on second belt pulley and the first belt pulley that corresponds, the top fixed mounting of axis of rotation has the loading and unloading auxiliary tray. The utility model is simple in operation, the practicality is strong, and is with low costs, can simulate the microgravity effect, can cooperate most of revolving wall type reaction vessel simultaneously, and can realize the three-dimensional dynamic cultivation work of culture dish, blake bottle, can adapt to the cultivation activity of liquid or solid-state culture medium.

Description

Cell and tissue rotary culture equipment

Technical Field

The utility model relates to a biological cultivation technical field especially relates to a cell and tissue gyration cultivation equipment.

Background

Biological culture refers to rapid growth and propagation of some (species) of microorganisms by means of artificially prepared culture media and artificially created culture conditions (such as culture temperature, etc.), and is called microbial culture, wherein biological culture includes cell and tissue culture, and in the case of cell and tissue culture, a culture dish or a culture bottle is required. At present, domestic and foreign researches show that the culture dish or the culture bottle can promote the culture work of cells and tissues in a three-dimensional dynamic environment, and particularly can generate a microgravity effect in rotary motion, which has great significance for researching the growth of the cells and the tissues in the microgravity environment. However, in the prior art, most of the revolving wall bioreactors come from europe and america, are very expensive, can only select revolving wall type reaction vessels provided by original manufacturers, cannot use general culture dishes or culture bottles, and are not suitable for culture work of non-liquid culture media, so that the problems of high use cost, small application range, inconvenient operation and the like exist, and a revolving culture device of cells and tissues with a new structure is provided for the purpose.

Disclosure of Invention

The utility model aims at solving the defects in the prior art and providing a rotary culture device for cells and tissues.

In order to achieve the above purpose, the utility model adopts the following technical scheme: the utility model provides a cell and tissue gyration cultivation equipment, includes the gyration seat casing, fixed mounting has driving motor in the gyration seat casing, fixed mounting has two first belt pulleys on driving motor's the output shaft, the symmetry rotates on the gyration seat casing and installs two axis of rotation, the bottom of axis of rotation extends to in the gyration seat casing, fixed cover is equipped with the second belt pulley in the axis of rotation, the cover is equipped with same belt on the first belt pulley of second belt pulley and correspondence, the top fixed mounting of axis of rotation has the loading and unloading auxiliary disc, the top of loading and unloading auxiliary disc is equipped with culture dish adaptation mechanism and blake bottle adaptation mechanism, the top fixed mounting of loading and unloading auxiliary disc has the spliced pole, spliced pole and culture dish adaptation mechanism and blake bottle adaptation mechanism swing joint.

Preferably, the culture dish adapter mechanism includes the swivel nut, the top fixed mounting of swivel nut has first support body, movable mounting has the chuck in the first support body, the screw rod is installed to the screw thread on the first support body, the one end of screw rod extend to in the first support body and with chuck fixed connection.

Preferably, blake bottle adapter mechanism is including connecting the shell, the top fixed mounting who connects the shell has the second support body, symmetry fixed mounting has a plurality of slide rails on the second support body, and is a plurality of slidable mounting has two holders on the slide rail, two fixed mounting has a plurality of springs on the holder.

Preferably, a thread groove is formed in the connecting column, and the inner wall of the thread groove is in threaded connection with the screw.

Preferably, the connecting column is provided with an external thread, and the external thread is in threaded connection with the threaded sleeve and the connecting shell.

Preferably, two supporting plates are symmetrically and fixedly installed in the rotary seat shell, and the supporting plates are rotatably connected with the corresponding rotating shafts.

Compared with the prior art, the beneficial effects of the utility model are that: by arranging the culture dish adapting mechanism, the culture dish can be conveniently fixed; by arranging the culture bottle adapting mechanism, the culture bottle can be conveniently fixed; by arranging the rotary seat shell, the driving motor, the rotating shaft and the loading and unloading auxiliary plate, the culture dish or the culture bottle can simulate the microgravity effect to culture organisms; by arranging the connecting column, the threaded sleeve and the connecting shell, the culture dish adapting mechanism and the culture bottle adapting mechanism are convenient to replace;

the utility model is simple in operation, the practicality is strong, and is with low costs, can simulate the microgravity effect, can cooperate most of revolving wall type reaction vessel simultaneously, and can realize the three-dimensional dynamic cultivation work of culture dish, blake bottle, can adapt to the cultivation activity of liquid or solid-state culture medium.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a perspective view of the culture dish adapter mechanism of FIG. 1;

FIG. 3 is a perspective view of the culture flask adaptation mechanism of FIG. 1.

In the figure: 1. a rotary seat housing; 2. a drive motor; 3. a first pulley; 4. a rotating shaft; 5. a second pulley; 6. a belt; 7. loading and unloading the auxiliary disc; 8. a culture dish adapting mechanism; 801. a threaded sleeve; 802. a first frame body; 803. a chuck; 804. a screw; 9. a culture flask adapting mechanism; 901. a connecting shell; 902. a second frame body; 903. a slide rail; 904. a clamping member; 905. a spring; 10. connecting columns.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: a cell and tissue rotary culture device comprises a rotary seat shell 1, wherein a driving motor 2 is fixedly installed in the rotary seat shell 1, two first belt pulleys 3 are fixedly installed on an output shaft of the driving motor 2, two rotating shafts 4 are symmetrically and rotatably installed on the rotary seat shell 1, the bottom ends of the rotating shafts 4 extend into the rotary seat shell 1, a second belt pulley 5 is fixedly sleeved on the rotating shafts 4, the second belt pulley 5 and the corresponding first belt pulley 3 are sleeved with the same belt 6, a loading and unloading auxiliary disc 7 is fixedly installed at the top end of each rotating shaft 4, a culture dish adapting mechanism 8 and a culture bottle adapting mechanism 9 are arranged above the loading and unloading auxiliary disc 7, a connecting column 10 is fixedly installed at the top of the loading and unloading auxiliary disc 7, and the connecting column 10 is movably connected with the culture dish adapting mechanism 8 and the culture bottle adapting mechanism 9;

culture dish adapter mechanism 8 includes swivel nut 801, swivel nut 801's top fixed mounting has first support body 802, movable mounting has chuck 803 in first support body 802, threaded mounting has screw rod 804 on first support body 802, the one end of screw rod 804 extend to in first support body 802 and with chuck 803 fixed connection, culture bottle adapter mechanism 9 is including connecting shell 901, the top fixed mounting of connecting shell 901 has second support body 902, symmetrical fixed mounting has a plurality of slide rails 903 on second support body 902, slidable mounting has two holders 904 on a plurality of slide rails 903, fixed mounting has a plurality of springs 905 on two holders 904, threaded groove has been seted up on the spliced pole 10, the inner wall and the screw rod 804 threaded connection of threaded groove, external screw thread has been seted up on the spliced pole 10, external screw thread and swivel nut 801 and connecting shell 901 threaded connection, the symmetry fixed mounting has two backup pads in the swivel base casing 1, the backup pad rotates with corresponding axis of rotation 4 and is connected.

By arranging the culture dish adapting mechanism 8, the culture dish can be conveniently fixed; by arranging the culture bottle adapting mechanism 9, the culture bottle can be conveniently fixed; by arranging the rotary seat shell 1, the driving motor 2, the rotating shaft 4 and the loading and unloading auxiliary disc 7, the culture dish or the culture bottle can simulate the microgravity effect to culture organisms; by arranging the connecting column 10, the screw sleeve 801 and the connecting shell 901, the culture dish adapting mechanism 8 and the culture bottle adapting mechanism 9 can be conveniently replaced; the utility model is simple in operation, the practicality is strong, and is with low costs, can simulate the microgravity effect, can cooperate most of revolving wall type reaction vessel simultaneously, and can realize the three-dimensional dynamic cultivation work of culture dish, blake bottle, can adapt to the cultivation activity of liquid or solid-state culture medium.

The working principle is as follows: when the culture dish adapting mechanism 8 or the culture bottle adapting mechanism 9 is used, the culture dish adapting mechanism 8 or the culture bottle adapting mechanism 9 is fixedly arranged on the loading and unloading auxiliary disc 7 in a matching way through the threaded sleeve 801 and the connecting shell 901 and the connecting column 10, the driving motor 2 is started, the first belt pulley 3 is driven to rotate by the driving motor 2, the first belt pulley 3 drives the second belt pulley 5 to rotate through the belt 6, and further drives the rotating shaft 4 to rotate, the rotating shaft 4 drives the loading and unloading auxiliary disc 7 to rotate, so that the culture dish adapting mechanism 8 or the culture bottle adapting mechanism 9 can rotate, a plurality of culture dishes are stacked in the first frame body 802, under the action of the rotating screw 804, the screw 804 rotates in the threaded sleeve 801, and the screw 804 drives the chuck 803 to move, so that the plurality of culture dishes; meanwhile, a plurality of culture bottles can be arranged in the second frame body 902 in parallel in sequence, and under the action of the spring 905, the culture bottles can be fixed through the two clamping pieces 904.

It should be noted that the device structure and the accompanying drawings of the present invention mainly describe the principle of the present invention, and in the technology of this design principle, the settings of the power mechanism, the power supply system, the control system, etc. of the device are not completely described, and the details of the power mechanism, the power supply system, and the control system can be clearly known on the premise that those skilled in the art understand the principle of the present invention.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. A cell and tissue rotary culture apparatus comprising a rotary seat housing (1), characterized in that: a driving motor (2) is fixedly arranged in the rotary seat shell (1), two first belt pulleys (3) are fixedly arranged on an output shaft of the driving motor (2), two rotating shafts (4) are symmetrically and rotatably arranged on the rotary seat shell (1), the bottom end of the rotating shaft (4) extends into the rotary seat shell (1), a second belt pulley (5) is fixedly sleeved on the rotating shaft (4), the second belt pulley (5) and the corresponding first belt pulley (3) are sleeved with the same belt (6), the top end of the rotating shaft (4) is fixedly provided with a loading and unloading auxiliary disc (7), a culture dish adapting mechanism (8) and a culture bottle adapting mechanism (9) are arranged above the loading and unloading auxiliary plate (7), the top of the loading and unloading auxiliary disc (7) is fixedly provided with a connecting column (10), the connecting column (10) is movably connected with the culture dish adapting mechanism (8) and the culture bottle adapting mechanism (9).

2. A cell and tissue culturing apparatus according to claim 1, wherein: culture dish adapter mechanism (8) include swivel nut (801), the top fixed mounting of swivel nut (801) has first support body (802), movable mounting has chuck (803) in first support body (802), screw rod (804) are installed to the screw thread on first support body (802), the one end of screw rod (804) extend to in first support body (802) and with chuck (803) fixed connection.

3. A cell and tissue culturing apparatus according to claim 2, wherein: the culture bottle adapting mechanism (9) comprises a connecting shell (901), a second frame body (902) is fixedly mounted at the top of the connecting shell (901), a plurality of sliding rails (903) are symmetrically and fixedly mounted on the second frame body (902), the sliding rails (903) are provided with two clamping pieces (904), and the clamping pieces (904) are provided with a plurality of springs (905).

4. A cell and tissue culturing apparatus according to claim 2, wherein: the connecting column (10) is provided with a thread groove, and the inner wall of the thread groove is in threaded connection with the screw (804).

5. A cell and tissue culturing apparatus according to claim 3, wherein: an external thread is arranged on the connecting column (10), and the external thread is in threaded connection with the thread sleeve (801) and the connecting shell (901).

6. A cell and tissue culturing apparatus according to claim 1, wherein: two supporting plates are symmetrically and fixedly installed in the rotary seat shell (1), and the supporting plates are rotatably connected with the corresponding rotating shafts (4).