CN212913907U - Transdermal patch - Google Patents
Transdermal patch Download PDFInfo
- Publication number
- CN212913907U CN212913907U CN202020521731.1U CN202020521731U CN212913907U CN 212913907 U CN212913907 U CN 212913907U CN 202020521731 U CN202020521731 U CN 202020521731U CN 212913907 U CN212913907 U CN 212913907U
- Authority
- CN
- China
- Prior art keywords
- foam
- electrode
- transdermal patch
- pet film
- frame
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000006260 foam Substances 0.000 claims abstract description 76
- 229920000742 Cotton Polymers 0.000 claims abstract description 28
- 229920002799 BoPET Polymers 0.000 claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 238000010521 absorption reaction Methods 0.000 claims abstract description 3
- 239000003292 glue Substances 0.000 claims description 8
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 5
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 4
- 229910021607 Silver chloride Inorganic materials 0.000 claims description 4
- 229910052709 silver Inorganic materials 0.000 claims description 4
- 239000004332 silver Substances 0.000 claims description 4
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims description 4
- 230000002745 absorbent Effects 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 description 11
- 229940079593 drug Drugs 0.000 description 9
- 229920000139 polyethylene terephthalate Polymers 0.000 description 7
- 239000012528 membrane Substances 0.000 description 6
- 238000013271 transdermal drug delivery Methods 0.000 description 6
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000012377 drug delivery Methods 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 229930000680 A04AD01 - Scopolamine Natural products 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 description 1
- 206010024604 Lipoatrophy Diseases 0.000 description 1
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000010579 first pass effect Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 description 1
- 229960002646 scopolamine Drugs 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000011285 therapeutic regimen Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
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- Electrotherapy Devices (AREA)
Abstract
The utility model discloses a transdermal paster, include: a PET film; the first foam is of a frame-shaped structure, the outer edge of the first foam is matched with the outer edge of the PET film, and the lower surface of the first foam is connected with the upper surface of the PET film; the water absorption cotton is arranged inside the frame-shaped structure of the first foam; the electrode is arranged on the absorbent cotton, and the connecting button is connected to the upper surface of the electrode; the lower surface of the second foam is connected with the upper surface of the first foam, and the upper end of the connecting button penetrates through and protrudes out of the second foam. The utility model has simple structure and convenient use, and can visually distinguish the positive electrode and the negative electrode.
Description
Technical Field
The utility model relates to the technical field of medical supplies, especially, relate to a transdermal paster.
Background
The raw material drugs are usually prepared into various dosage forms, and the administration mode or route is different according to different dosage forms, and oral administration, injection administration, nasal administration, transdermal administration and the like are common. In the middle of the 20 th 70 th century, the american people first proposed a therapeutic regimen for transdermal controlled release drug delivery and also prepared scopolamine patches, transdermal drug delivery systems were also rapidly developed and improved to a certain extent, and more research efforts were made on drug selection and testing for transdermal drug delivery. The transdermal drug delivery system is a preparation form which is used for delivering drugs on the surface of the skin, so that the drugs pass through all layers of the skin at a constant speed (or close to the constant speed) and enter the systemic circulation to produce systemic or local treatment effects. Especially for macromolecular protein, polypeptide drugs, vaccines and the like, the drugs can not be taken orally, but only can be administered by adopting an injection method, but adverse reactions such as lipoatrophy, induration and the like are easily caused by long-term injection, the compliance of patients is low, and the administration needs to be carried out by professional staff, so that much inconvenience is caused. When the transdermal drug delivery system is used for drug delivery, the problems caused by other drug delivery routes can be avoided, such as liver first-pass effect and gastrointestinal inactivation can be avoided so as to avoid reducing the utilization rate of the drug; can maintain constant blood concentration or pharmacological effect; can also improve the bioavailability of drugs such as protein or polypeptide drugs; and adverse drug reactions can be reduced, side effects caused by injection can not be caused, and in addition, patients can independently take the medicine, so that the medicine is more humanized and the compliance of the patients can be greatly improved.
Therefore, in order to achieve transdermal drug delivery, it is necessary to design a transdermal patch that can be exclusively used for transdermal drug delivery.
SUMMERY OF THE UTILITY MODEL
In view of this, the present invention provides a transdermal patch.
In order to realize the purpose, the utility model discloses the technical scheme who takes does:
a transdermal patch, comprising:
a PET film;
the first foam is of a frame-shaped structure, the outer edge of the first foam is matched with the outer edge of the PET film, and the lower surface of the first foam is connected with the upper surface of the PET film;
the water absorption cotton is arranged inside the frame-shaped structure of the first foam;
the electrode is arranged on the absorbent cotton, and the connecting button is connected to the upper surface of the electrode;
the lower surface of the second foam is connected with the upper surface of the first foam, and the upper end of the connecting button penetrates through and protrudes out of the second foam.
In the transdermal patch, the PET film, the first foam and the second foam surround to form an accommodating space, and the absorbent cotton, the electrode and the connecting button are all arranged in the accommodating space.
In the transdermal patch, the outer edge of the PET film, the frame-shaped structure and the outer edge of the second foam are semicircular.
In the transdermal patch, an inner side of one side of the frame-shaped structure extends inwards to form a protrusion.
In the transdermal patch, the outer side of one side of the frame structure extends inwards to form a groove.
In the transdermal patch, the absorbent cotton and the electrode are bonded through acrylic acid glue.
In the transdermal patch, the electrode is a silver electrode or a silver chloride electrode.
In the transdermal patch, the first foam and the second foam are both PVC foam films.
The utility model discloses owing to adopted above-mentioned technique, make it compare the positive effect that has with prior art and be:
(1) the utility model has simple structure and convenient use, and can visually distinguish the positive electrode and the negative electrode.
Drawings
Fig. 1 is an exploded view of a first embodiment of a transdermal patch of the present invention.
Fig. 2 is a perspective view of a first embodiment of the transdermal patch of the present invention.
Fig. 3 is a top view of a first embodiment of a transdermal patch of the present invention.
Fig. 4 is an exploded view of a second embodiment of a transdermal patch of the present invention.
Fig. 5 is a perspective view of a second embodiment of a transdermal patch of the present invention.
Fig. 6 is a top view of a second embodiment of a transdermal patch of the present invention.
In the drawings: 1. a PET film; 2. first foam; 21. a protrusion; 22. a groove; 3. absorbent cotton; 4. an electrode; 5. connecting a button; 6. and the second foam.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and specific embodiments, but the present invention is not limited thereto.
The first embodiment:
fig. 1 is an exploded view of a first embodiment of a transdermal patch of the present invention, fig. 2 is a perspective view of the first embodiment of the transdermal patch of the present invention, and fig. 3 is a plan view of the first embodiment of the transdermal patch of the present invention, and fig. 1 to 3 show a first preferred embodiment of the transdermal patch, including: PET membrane 1 and first bubble are cotton 2, and first bubble is cotton 2 for the frame type structure, and the outer fringe of first bubble cotton 2 and the outer fringe phase-match of PET membrane 1, the lower surface of first bubble cotton 2 is connected with the upper surface of PET membrane 1.
Further, as a preferred embodiment, the transdermal patch further comprises: the absorbent cotton 3 is arranged in the frame-shaped structure of the first foam 2.
Further, as a preferred embodiment, the transdermal patch further comprises: the electrode 4 and connect button 5, the electrode 4 is located on the cotton 3 that absorbs water, connects button 5 and connects the upper surface in electrode 4.
Further, as a preferred embodiment, the transdermal patch further comprises: the lower surface of the second foam 6 is connected with the upper surface of the first foam 2, and the upper end of the connecting button 5 penetrates through and protrudes out of the second foam 6.
Further, as a preferred embodiment, the PET film 1, the first foam 2 and the second foam 6 surround to form an accommodating space, and the absorbent cotton 3, the electrode 4 and the connection button 5 are all disposed in the accommodating space.
The above description is only an example of the preferred embodiments of the present invention, and the embodiments and the protection scope of the present invention are not limited thereby.
The utility model discloses still have following embodiment on above-mentioned basis:
in a further embodiment of the present invention, the outer edge of the PET film 1, the frame structure of the first foam 2, and the outer edge of the second foam 6 are all semicircular.
In a further embodiment of the present invention, a protrusion 21 is formed by extending inward the inner side of one side of the frame structure of the first foam 2.
In the further embodiment of the utility model, the water-absorbing cotton 3 is bonded with the electrode 4 through acrylic acid glue.
In a further embodiment of the present invention, the electrode 4 is a silver electrode or a silver chloride electrode.
In a further embodiment of the present invention, the first foam 2 and the second foam 6 are PVC foam films.
In a further embodiment of the present invention, the first foam 2 is white foam, and the second foam 6 is skin color foam.
In a further embodiment of the present invention, the thickness of the PET film 1 is preferably 25 μm, the thickness of the first foam 2 is preferably 2mm, and the thickness of the second foam 6 is preferably 0.5 mm.
The utility model discloses a further embodiment, connect button 5 and be the pin thread, the preferred copper of material, the preferred 2.3mm of diameter of connecting button 5.
In a further embodiment of the present invention, the diameter of the electrode 4 is preferably 20mm, and the thickness of the electrode 4 is preferably 0.5 mm.
Second embodiment:
fig. 4 is an exploded view of a second embodiment of the transdermal patch of the present invention, fig. 5 is a perspective view of the second embodiment of the transdermal patch of the present invention, and fig. 6 is a plan view of the second embodiment of the transdermal patch of the present invention, and fig. 4 to 6 show a second preferred embodiment of the transdermal patch, including: PET membrane 1 and first bubble are cotton 2, and first bubble is cotton 2 for the frame type structure, and the outer fringe of first bubble cotton 2 and the outer fringe phase-match of PET membrane 1, the lower surface of first bubble cotton 2 is connected with the upper surface of PET membrane 1.
Further, as a preferred embodiment, the transdermal patch further comprises: the absorbent cotton 3 is arranged in the frame-shaped structure of the first foam 2.
Further, as a preferred embodiment, the transdermal patch further comprises: the electrode 4 and connect button 5, the electrode 4 is located on the cotton 3 that absorbs water, connects button 5 and connects the upper surface in electrode 4.
Further, as a preferred embodiment, the transdermal patch further comprises: the lower surface of the second foam 6 is connected with the upper surface of the first foam 2, and the upper end of the connecting button 5 penetrates through and protrudes out of the second foam 6.
Further, as a preferred embodiment, the PET film 1, the first foam 2 and the second foam 6 surround to form an accommodating space, and the absorbent cotton 3, the electrode 4 and the connection button 5 are all disposed in the accommodating space.
The above description is only an example of the preferred embodiments of the present invention, and the embodiments and the protection scope of the present invention are not limited thereby.
The utility model discloses still have following embodiment on above-mentioned basis:
in a further embodiment of the present invention, the outer edge of the PET film 1, the frame structure of the first foam 2, and the outer edge of the second foam 6 are all semicircular.
In a further embodiment of the present invention, a protrusion 21 is formed by extending inward the inner side of one side of the frame structure of the first foam 2.
In a further embodiment of the present invention, the outer side of one side of the frame structure of the first foam 2 extends inwards to form a groove 22.
In a further embodiment of the invention, the recess 22 is aligned with the protrusion 21.
In the further embodiment of the utility model, the water-absorbing cotton 3 is bonded with the electrode 4 through acrylic acid glue.
In a further embodiment of the present invention, the electrode 4 is a silver electrode or a silver chloride electrode.
In a further embodiment of the present invention, the first foam 2 and the second foam 6 are PVC foam films.
In a further embodiment of the present invention, the first foam 2 is white foam, and the second foam 6 is skin color foam.
By the first embodiment and the second embodiment, respectively, it is possible to directly and clearly distinguish the positive electrode and the negative electrode, preventing the electrodes from being connected in the opposite direction.
The following describes the preparation method of the present invention:
step S1: uniformly coating acrylic acid glue on a PET film 1 (the glue content is 37 +/-5 g/square meter), drying (drying at 110 ℃ for 3 minutes), and transferring to the rough surface and the anti-seepage film of second foam 6 and water absorbent cotton 3;
step S2: the surface with glue of the second foam 6 is bonded with the surface without glue of the first foam 2;
step S3: the connecting button 5 penetrates through the second foam 6 from the middle of the adhesive surface of the second foam 6, and then the electrode plate 4 is attached;
step S4: the adhesive surface of the absorbent cotton 3 is adhered to the electrode sheet 4, and an anti-sticking film (PET release film) is covered.
The above description is only an example of the preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and those skilled in the art should be able to realize the equivalent alternatives and obvious variations of the present invention.
Claims (8)
1. A transdermal patch, comprising:
a PET film;
the first foam is of a frame-shaped structure, the outer edge of the first foam is matched with the outer edge of the PET film, and the lower surface of the first foam is connected with the upper surface of the PET film;
the water absorption cotton is arranged inside the frame-shaped structure of the first foam;
the electrode is arranged on the absorbent cotton, and the connecting button is connected to the upper surface of the electrode;
the lower surface of the second foam is connected with the upper surface of the first foam, and the upper end of the connecting button penetrates through and protrudes out of the second foam.
2. The transdermal patch according to claim 1, wherein the PET film, the first foam and the second foam surround to form a containing space, and the absorbent foam, the electrode and the connecting button are all arranged in the containing space.
3. The transdermal patch according to claim 1, wherein the outer edge of the PET film, the frame structure, and the outer edge of the second foam are each semicircular.
4. The transdermal patch according to claim 1, wherein the inner side of one side of the frame-shaped structure is extended inward to form a protrusion.
5. The transdermal patch according to claim 1 or 4, wherein the outer side of one side of the frame-shaped structure is extended inward to form a groove.
6. The transdermal patch according to claim 1, wherein the absorbent cotton is bonded to the electrode by acrylic glue.
7. The transdermal patch according to claim 1, wherein the electrode is a silver electrode or a silver chloride electrode.
8. The transdermal patch according to claim 1, wherein the first foam and the second foam are both PVC foam films.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020521731.1U CN212913907U (en) | 2020-04-10 | 2020-04-10 | Transdermal patch |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020521731.1U CN212913907U (en) | 2020-04-10 | 2020-04-10 | Transdermal patch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212913907U true CN212913907U (en) | 2021-04-09 |
Family
ID=75296906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020521731.1U Active CN212913907U (en) | 2020-04-10 | 2020-04-10 | Transdermal patch |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212913907U (en) |
-
2020
- 2020-04-10 CN CN202020521731.1U patent/CN212913907U/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240607 Address after: 213000 No. 55, Yuejin Road, Zou District Town, Zhonglou District, Changzhou City, Jiangsu Province Patentee after: Changzhou Hualian medical device group Co.,Ltd. Country or region after: China Address before: 213000 industrial concentration area, Zou District, Zhonglou District, Changzhou City, Jiangsu Province (65 Huiling West Road) Patentee before: CHANGZHOU HUAJIA MEDICAL DEVICE Ltd. Country or region before: China |