CN212864780U

CN212864780U - Hybridoma cell strain continuous culture device

Info

Publication number: CN212864780U
Application number: CN202021580408.8U
Authority: CN
Inventors: 盘其伟; 胡红宇
Original assignee: Shenzhen Huabai Biotechnology Co ltd
Current assignee: Shenzhen Huabai Biotechnology Co ltd
Priority date: 2020-08-03
Filing date: 2020-08-03
Publication date: 2021-04-02
Anticipated expiration: 2030-08-03

Abstract

The utility model relates to a hybridoma cell strain continuous culture device, which comprises a base, an incubator is fixedly arranged at the top of the base, a heat dissipation plate and an electric heating pipe are symmetrically and fixedly arranged at the top of an inner cavity of the incubator and the bottom of the inner cavity, heat conduction oil is filled in a cavity formed between the heat dissipation plate and the incubator, two groups of heat dissipation plates are provided with a rotating column through rotating a rotating shaft, the electric heating pipe can heat the heat conduction oil, the heat conduction oil can transfer heat to the heat dissipation plate, the heat dissipation plate can dissipate the heat to the inner cavity of the incubator to heat and warm the inner cavity of the incubator, the temperature and the humidity of the inner cavity of the incubator can be detected through arranging a temperature detector and a humidity detector, the temperature and the humidity can be conveniently regulated and controlled, the camera can record the cells in a culture dish placed at the top of a supporting plate without, the change of the environment inside the incubator can be prevented.

Description

Hybridoma cell strain continuous culture device

Technical Field

The utility model relates to a hybridoma cell strain continuous culture device belongs to cell culture technical field.

Background

The monoclonal antibody has wide application, and can be used for diagnosis, treatment and the like of diseases. The monoclonal antibody for diagnosis at present is mainly derived from a ascites method or a cell culture method, the used cells are mainly hybridoma cells, the difference between batches of products obtained by the ascites method is large, and the cells relate to animal ethics, and the cells are gradually replaced by the cell culture method.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the technical problem of overcoming the existing defects, the utility model provides a hybridoma cell strain continuous culture device, the cells can be observed without taking out the culture dish, the temperature adjustment is convenient, the electric heating pipe can heat the heat conducting oil by arranging the electric heating pipe, the heat conducting oil can transmit the heat to the heat radiating plate, the heat radiating plate can radiate the heat to the inner cavity of the culture box, the inner cavity of the culture box can be heated and heated, the temperature and the humidity of the inner cavity of the culture box can be detected by arranging the temperature detector and the humidity detector, the temperature and the humidity can be conveniently adjusted and controlled, the camera can record the video of the cells in the culture dish placed at the top of the supporting plate by arranging the camera, the cells can be observed without taking out the culture dish, the environment in the culture box can be prevented from changing, the electric telescopic rod can control the left and right movement, the gear plate is controlled to move left and right to control the rotation of the gear, so that the supporting plate can be controlled to rotate, the camera can record videos of cells inside each culture dish placed at the top of the supporting plate, the culture box inner cavity is conveniently ventilated through the ventilation port, and the dust filter screen can prevent dust from entering the culture box inner cavity and can effectively solve the problems in the background art.

In order to solve the technical problem, the utility model provides a following technical scheme:

the utility model provides a hybridoma cell strain continuous culture device, includes the base, the fixed incubator that is equipped with in base top, incubator inner chamber top and inner chamber bottom symmetry are fixed and are equipped with heating panel and electric heating pipe, the inside packing of cavity that forms between heating panel and the incubator has the conduction oil, and is two sets of rotate through the pivot between the heating panel and be equipped with the rotation post, the fixed layer board that is equipped with in the rotation post outside, the fixed gear that is equipped with in rotation post bottom outside, the fixed electric telescopic handle that is equipped with in incubator inner chamber bottom one side, the fixed gear board that is equipped with of electric telescopic handle one end, the incubator left and right sides is fixed respectively and is equipped with temperature-detecting instrument and moisture detector, incubator inner chamber both sides.

As further description of the technical scheme, the sensing probes of the temperature detector and the humidity detector are both fixedly arranged in the inner cavity of the incubator.

As further described in the above technical solutions, a cabinet door is connected to the front side surface of the incubator through a hinge shaft.

As further description of the technical scheme, the middle part of the cabinet door is provided with a ventilation opening, and a dust filter screen is fixedly arranged in the inner cavity of the ventilation opening.

As further described in the technical scheme, the front side surface of the cabinet door is rotatably provided with a cover plate through a hinge shaft.

As further description of the technical scheme, culture dish storage grooves are formed in the top surface of the supporting plate at equal intervals.

The utility model discloses beneficial effect: 1. the electric heating pipe can heat the heat-conducting oil, the heat-conducting oil can transfer heat to the heat-radiating plate, the heat-radiating plate can radiate the heat to the inner cavity of the incubator, the inner cavity of the incubator can be heated, the temperature and the humidity of the inner cavity of the incubator can be detected by arranging the temperature detector and the humidity detector, and the temperature and the humidity can be conveniently regulated and controlled;

2. by arranging the camera, the camera can record the video of the cells in the culture dish placed at the top of the supporting plate, the cells can be observed without taking out the culture dish, and the change of the environment in the incubator can be prevented;

3. through setting up electric telescopic handle, electric telescopic handle can control the gear board and remove about, and the gear board is removed about and can be controlled the gear rotation, and then can control the layer board rotatory, makes the camera can carry out the video recording to the inside cell of every culture dish that the layer board top was placed, conveniently ventilates the incubator inner chamber through setting up ventilative mouthful, and the dust filter screen can prevent that the dust from getting into the incubator inner chamber.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention.

FIG. 1 is a sectional view of the continuous culture apparatus for hybridoma cell lines.

FIG. 2 is a front view of the continuous culture device for hybridoma cell strains.

FIG. 3 is a top view of a support plate of the continuous culture apparatus for hybridoma cell strains.

Reference numbers in the figures: 1. a base; 2. an incubator; 3. a heat dissipation plate; 4. an electric heating tube; 5. heat conducting oil; 6. rotating the column; 7. a support plate; 8. a gear; 9. an electric telescopic rod; 10. a gear plate; 11. a temperature detector; 12. a humidity detector; 13. a camera; 14. a cabinet door; 15. a ventilation opening; 16. a dust filter screen; 17. a cover plate; 18. culture dish storing tank.

Detailed Description

The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are presented herein only to illustrate and explain the present invention, and not to limit the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: a hybridoma cell strain continuous culture device comprises a base 1, wherein an incubator 2 is fixedly arranged at the top of the base 1, a heat dissipation plate 3 and an electric heating pipe 4 are symmetrically and fixedly arranged at the top of an inner cavity of the incubator 2 and the bottom of the inner cavity, the electric heating pipe 4 can heat conduction oil 5, the heat conduction oil 5 can transfer heat to the heat dissipation plate 3, the heat dissipation plate 3 can dissipate the heat to the inner cavity of the incubator 2, the inner cavity of the incubator 2 can be heated, the heat conduction oil 5 is filled in a cavity formed between the heat dissipation plate 3 and the incubator 2, a rotating column 6 is arranged between the two groups of heat dissipation plates 3 through rotation of a rotating shaft, a supporting plate 7 is fixedly arranged at the outer side of the rotating column 6, a gear 8 is fixedly arranged at the outer side of the bottom of the rotating column 6, an electric telescopic rod 9 is fixedly arranged at one, it can control the gear 8 rotatory to remove about gear plate 10, and then can control layer board 7 rotatory, makes camera 13 can record a video to the inside cell of every culture dish that 7 tops of layer board were placed, the fixed gear plate 10 that is equipped with of 9 one ends of electric telescopic handle, 2 left and right sides of incubator are fixed respectively and are equipped with temperature-detecting instrument 11 and moisture meter 12, and temperature-detecting instrument 11 and moisture meter 12 can detect the temperature and humidity of 2 inner chambers of incubator, the temperature and humidity regulation and control of being convenient for, 2 inner chamber both sides of incubator are fixed respectively and are equipped with camera 13, and camera 13 can record a video to the inside cell of the culture dish that 7 tops of layer board were placed, need not take out the culture dish and can observe the cell, can prevent that the inside environment of incubator 2 from changing.

Specifically, as shown in fig. 1, the inductive probes of the temperature detector 11 and the humidity detector 12 are all fixedly arranged in the inner cavity of the incubator 2, so that the temperature detector 11 and the humidity detector 12 can detect the temperature and the humidity in the inner cavity of the incubator 2, and the temperature and the humidity can be conveniently regulated and controlled.

Specifically, as shown in fig. 2, the front side surface of the incubator 2 is connected with a cabinet door 14 through a hinge, a ventilation opening 15 is formed in the middle of the cabinet door 14, a dust filter screen 16 is fixedly arranged in an inner cavity of the ventilation opening 15, the ventilation opening 15 is arranged to facilitate ventilation of the inner cavity of the incubator 2, the dust filter screen 16 can prevent dust from entering the inner cavity of the incubator 2, a cover plate 17 is arranged on the front side surface of the cabinet door 14 through rotation of the hinge, and the size of an opening of the ventilation opening 15 can be regulated and controlled through the cover plate 17.

Specifically, as shown in fig. 3, culture dish storage grooves 18 are equidistantly formed in the top surface of the supporting plate 7, so that culture dishes can be conveniently stored.

The utility model discloses the theory of operation: conduction oil 5 can give heating panel 3 heat transfer, heating panel 3 can give off the heat to 2 inner chambers of incubator, can heat the intensification to 2 inner chambers of incubator, electric telescopic handle 9 can control about gear plate 10, it can control gear 8 rotatory to control about gear plate 10, and then can control layer board 7 rotatory, make camera 13 can record a video to the inside cell of every culture dish that layer board 7 top was placed, camera 13 can record a video to the inside cell of the culture dish that layer board 7 top was placed, need not take out the culture dish and can observe the cell, can prevent that the inside environment of incubator 2 from changing, temperature detector 11 and moisture detector 12 can detect the temperature and humidity of 2 inner chambers of incubator, the temperature and humidity regulation and control of being convenient for.

The above is the preferred embodiment of the present invention, and the technical personnel in the field of the present invention can also change and modify the above embodiment, therefore, the present invention is not limited to the above specific embodiment, and any obvious improvement, replacement or modification made by the technical personnel in the field on the basis of the present invention all belong to the protection scope of the present invention.

Claims

1. The utility model provides a hybridoma cell strain continuous culture device, includes base (1), its characterized in that: the top of the base (1) is fixedly provided with an incubator (2), the top of the inner cavity of the incubator (2) and the bottom of the inner cavity are symmetrically and fixedly provided with a heat dissipation plate (3) and an electric heating pipe (4), a cavity formed between the heat dissipation plates (3) and the incubator (2) is filled with heat conduction oil (5), a rotating column (6) is rotatably arranged between the two groups of heat dissipation plates (3) through a rotating shaft, a supporting plate (7) is fixedly arranged on the outer side of the rotating column (6), a gear (8) is fixedly arranged on the outer side of the bottom of the rotating column (6), an electric telescopic rod (9) is fixedly arranged on one side of the bottom of the inner cavity of the incubator (2), one end of the electric telescopic rod (9) is fixedly provided with a gear plate (10), the left side and the right side of the incubator (2) are respectively and fixedly provided with a temperature detector (11) and a humidity detector (12), cameras (13) are respectively fixedly arranged on two sides of the inner cavity of the incubator (2).

2. The continuous culture device of hybridoma cell strain according to claim 1, wherein: and the sensing probes of the temperature detector (11) and the humidity detector (12) are fixedly arranged in the inner cavity of the incubator (2).

3. The continuous culture device of hybridoma cell strain according to claim 1, wherein: the front side surface of the incubator (2) is connected with a cabinet door (14) through a hinge shaft.

4. The continuous culture device of hybridoma cell strain according to claim 3, wherein: the middle part of the cabinet door (14) is provided with a ventilation opening (15), and an inner cavity of the ventilation opening (15) is fixedly provided with a dust filter screen (16).

5. The continuous culture device of hybridoma cell strain according to claim 4, wherein: the front side surface of the cabinet door (14) is rotatably provided with a cover plate (17) through a hinge shaft.

6. The continuous culture device of hybridoma cell strain according to claim 1, wherein: and culture dish storage grooves (18) are arranged on the top surface of the supporting plate (7) at equal intervals.