CN212855694U - Simple parallel reactor - Google Patents

Simple parallel reactor Download PDF

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Publication number
CN212855694U
CN212855694U CN202021102064.XU CN202021102064U CN212855694U CN 212855694 U CN212855694 U CN 212855694U CN 202021102064 U CN202021102064 U CN 202021102064U CN 212855694 U CN212855694 U CN 212855694U
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reaction
parallel reactor
pressure system
gas exchanger
simple parallel
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张安林
周玥
邓泽平
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Hunan Cancer Hospital
Hunan Huateng Pharmaceutical Co Ltd
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Hunan Cancer Hospital
Hunan Huateng Pharmaceutical Co Ltd
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Abstract

The invention provides a simple parallel reactor which comprises a feeding device, a plurality of reaction devices, a gas exchanger, a product receiving device, a positive pressure system and a negative pressure system, wherein the upper end of each reaction device is connected with the feeding device through a feeding valve, the lower end of each reaction device is connected with the gas exchanger through a discharging valve, the gas exchanger is correspondingly provided with a plurality of partition plates with openings at the upper ends according to the number of the connected reaction devices, the lower end of the gas exchanger is connected with the product receiving device through a connecting valve, and the other two ends of the gas exchanger are respectively connected with the positive pressure system and the negative pressure system. The parallel reactor can be used for the synthesis scientific research of reaction route exploration, condition optimization, high-efficiency synthesis and the like, can effectively control the conditions of reaction temperature, reaction rate, water-oxygen condition, air tightness, light avoidance and the like, is suitable for the parallel synthesis reaction of micro volume or small volume, simplifies the experimental link, accelerates the research and development process, and saves time and cost.

Description

Simple parallel reactor
Technical Field
The invention relates to a simple parallel reactor.
Background
The parallel reactor is a multi-reaction-platform instrument, can be used for synthetic scientific researches such as reaction route exploration, condition optimization, high-efficiency synthesis and the like, is suitable for parallel synthetic reaction with micro volume or small volume, and has the advantages of portability, high efficiency, repeatability and the like. The parallel reactors have strict requirements on the control of reaction conditions, such as: in order to achieve the above control, the parallel reactors in the market are complex and expensive, and it is necessary to provide a simple parallel reactor with simple device, easy operation and low cost to solve the above problems.
Disclosure of Invention
The invention provides a parallel reactor which adopts gas bubbling stirring and sand core filtering, is simple and convenient to operate and is low in price.
In order to achieve the purpose of the invention, the invention adopts the following technical scheme:
a simple parallel reactor is characterized in that: simple and easy parallel reactor includes feed arrangement, a plurality of reaction unit, gas exchanger, result receiving arrangement, malleation system, negative pressure system, the reaction unit upper end is passed through the feed valve and is connected with feed arrangement, and the reaction unit lower extreme passes through the bleeder valve and links to each other with gas exchanger, gas exchanger is according to the corresponding a plurality of upper ends that are provided with of the reaction unit quantity of connecting for open-ended baffle, and gas exchanger lower extreme links to each other with the result receiving arrangement through the connecting valve, malleation system and negative pressure system are connected respectively to gas exchanger's other both ends.
When the reaction starts, gas (air, oxygen, inert gas and the like) is blown in or exhausted by opening the positive pressure system or the negative pressure system to provide different reaction atmospheres, and meanwhile, the gas blown in by controlling the positive pressure system enters the reaction device to achieve the purposes of bubbling, stirring and accelerating the reaction. And when the reaction is finished, the positive pressure system is closed, and the negative pressure system is opened to control the pressure in the reaction device so as to discharge the reaction product into the product receiving device in an accelerated manner.
Preferably, the material of the discharging part at the lower end of the reaction device is a sand core.
When the product is liquid, the lower end of the reaction device can be set to be made of sand core materials, so that solid products can be prevented from entering the gas exchanger through the discharge valve, the purity of the product is ensured, the filtering operation is reduced, and the reaction device is simplified.
Preferably, the connection part of the upper end of the reaction device and the feed valve is a detachable part.
In order to conveniently clean the reaction device, the joint of the upper end of the reaction device and the feed valve can be detachably arranged.
Preferably, the number of the partitions of the gas exchanger is one more than that of the reaction device.
Preferably, the positive pressure system is an inert gas booster pump.
When the reaction needs to be carried out under the protection of inert gas, the inert gas can be pumped in through an inert gas pressurizing pump; when the reaction is required under vacuum, air can be vented through a negative pressure system.
Preferably, a temperature control device is arranged between the gas exchanger and the positive pressure system.
Preferably, the gas heating device is a thermostatic bath.
When the reaction needs to be carried out under the condition of high temperature or low temperature, the pumped gas can be heated or cooled by the constant temperature tank so as to achieve the purpose of controlling the reaction temperature.
Preferably, a gas drying device is arranged between the gas exchanger and the positive pressure system.
Preferably, the gas drying device is a calcium chloride device.
When the reaction is carried out under dry conditions, the dryness of the reaction device can be controlled by controlling the gas pumped in by the drying pump.
Preferably, the feeding device, the reaction device, the gas exchanger and the product receiving device are brown light-proof vessels.
When the reaction carried out in the reactor is sensitive to light and it is necessary to carry out the reaction under a light-shielding condition, the color of the parallel reactor may be set to a light-shielding color such as brown.
The simple parallel reactor can be used for synthetic scientific researches such as reaction route exploration, condition optimization, high-efficiency synthesis and the like, can effectively control conditions such as reaction temperature, reaction rate, water-oxygen condition, air tightness, light shielding and the like, is suitable for parallel synthesis reaction with micro volume or small volume, simplifies experimental links, accelerates research and development process, and saves time and cost.
Drawings
FIG. 1 is a schematic view of a simple parallel reactor
Description of reference numerals: 1. a feed valve; 2. a reaction device; 3. a sand core; 4. a discharge valve; 5. a gas exchange device; 6. a gas exchange device separator; 7. a connecting valve; 8. a pressure reducing pump; 9. a thermostatic bath; 10. a calcium chloride unit; 11. pressure pump
Detailed Description
To facilitate understanding, the present application will now be described more fully hereinafter with reference to the accompanying drawings, in which preferred embodiments of the application are shown. This application may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in FIG. 1, the parallel reactor has eight reaction units 2, the upper ends of the reaction units 2 are respectively connected with a feeding device (not shown) through feeding valves 1, the lower ends of the reaction units 2 are respectively connected with a gas exchanger 5 through discharging valves 4, the gas exchanger 5 is correspondingly provided with nine partition plates 6 with the upper ends being open according to the eight reaction units 2 connected, the lower ends of the gas exchanger 5 are respectively connected with a product receiving device (not shown) through connecting valves 7, the other two ends of the gas exchanger 5 are respectively connected with a booster pump 11 and a decompression pump 8, and a calcium chloride drying device 10 and a constant temperature tank 9 are connected with the booster pump 11.
Wherein the reaction device 2 is 20cm high and 10cm in diameter, and the gas exchanger 5 is 10cm high and 20cm in diameter.
Before the reaction, the reactants are fed into the reaction apparatus 2 through a feeding means (not shown), and air may be pumped out by a decompression pump 8 to provide vacuum reaction conditions, or gas (air, oxygen, inert gas, etc.) may be blown in by a pressurization pump to provide different reaction atmospheres.
When the reaction needs stirring, the gas can be blown into the reaction device by controlling the pressure pump to achieve bubbling stirring. When the reaction needs to be carried out under the condition of high temperature or low temperature, the thermostatic bath can be opened to heat or cool the pumped gas so as to achieve the purpose of controlling the reaction temperature. When the reaction needs to be carried out under a dry condition, the calcium chloride drying device can be started to control the gas pumped by the drying pump so as to control the dryness of the reaction device.
Wherein the controllable temperature range of the constant temperature bath is-10 ℃ to 80 ℃.
After the reaction is completed, the pressure increasing pump 11 is closed, and the pressure reducing pump 8 is started to control the pressure in the reaction device 2 so as to accelerate the discharge of the reaction product into a product receiving device (not shown).
When the reaction carried out in the reactor is sensitive to light and it is necessary to carry out the reaction under a light-shielding condition, the color of the parallel reactor may be set to a light-shielding color such as brown.
The invention provides a parallel reactor which adopts gas bubbling stirring and sand core filtering, is simple and convenient to operate and is low in price.

Claims (10)

1.一种简易平行反应器,其特征在于:所述简易平行反应器包括进料装置、多个反应装置、气体交换器、产物接收装置、正压系统、负压系统,所述反应装置上端通过进料阀与进料装置连接,反应装置下端通过出料阀与气体交换器相连,所述气体交换器根据连接的反应装置数量相应的设置有多个上端为开口的隔板,气体交换器下端通过连接阀与产物接收装置相连,所述气体交换器的另外两端分别连接正压系统和负压系统。1. a simple parallel reactor, it is characterized in that: described simple parallel reactor comprises feeding device, a plurality of reaction devices, gas exchanger, product receiving device, positive pressure system, negative pressure system, and described reaction device upper end It is connected with the feeding device through the feeding valve, and the lower end of the reaction device is connected with the gas exchanger through the discharging valve. The lower end is connected to the product receiving device through a connection valve, and the other ends of the gas exchanger are respectively connected to a positive pressure system and a negative pressure system. 2.根据权利要求1所述的一种简易平行反应器,其特征在于,所述反应装置下端出料部位材质为砂芯。2 . A simple parallel reactor according to claim 1 , wherein the material of the discharge part at the lower end of the reaction device is sand core. 3 . 3.根据权利要求2所述的一种简易平行反应器,其特征在于,所述反应装置上端与进料阀连接处为可拆卸部位。3 . The simple parallel reactor according to claim 2 , wherein the connection between the upper end of the reaction device and the feed valve is a detachable part. 4 . 4.根据权利要求3所述的一种简易平行反应器,其特征在于,所述气体交换器的隔板的数量比反应装置多一个。4 . The simple parallel reactor according to claim 3 , wherein the number of partitions of the gas exchanger is one more than that of the reaction device. 5 . 5.根据权利要求4所述的一种简易平行反应器,其特征在于,所述正压系统为惰性气体加压泵。5 . A simple parallel reactor according to claim 4 , wherein the positive pressure system is an inert gas pressure pump. 6 . 6.根据权利要求5所述的一种简易平行反应器,其特征在于,所述气体交换器与正压系统之间设置有控温装置。6 . The simple parallel reactor according to claim 5 , wherein a temperature control device is arranged between the gas exchanger and the positive pressure system. 7 . 7.根据权利要求6所述的一种简易平行反应器,其特征在于,所述控温装置为恒温槽。7 . A simple parallel reactor according to claim 6 , wherein the temperature control device is a constant temperature tank. 8 . 8.根据权利要求7所述的一种简易平行反应器,其特征在于,所述气体交换器与正压系统之间设置有气体干燥装置。8 . The simple parallel reactor according to claim 7 , wherein a gas drying device is arranged between the gas exchanger and the positive pressure system. 9 . 9.根据权利要求8所述的一种简易平行反应器,其特征在于,所述气体干燥装置为氯化钙装置。9 . A simple parallel reactor according to claim 8 , wherein the gas drying device is a calcium chloride device. 10 . 10.根据权利要求1-9任一项所述的一种简易平行反应器,其特征在于,所述进料装置、反应装置、气体交换器、产物接收装置均为棕色避光器皿。10 . The simple parallel reactor according to claim 1 , wherein the feeding device, the reaction device, the gas exchanger, and the product receiving device are all brown light-shielding vessels. 11 .
CN202021102064.XU 2020-06-15 2020-06-15 Simple parallel reactor Active CN212855694U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021102064.XU CN212855694U (en) 2020-06-15 2020-06-15 Simple parallel reactor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021102064.XU CN212855694U (en) 2020-06-15 2020-06-15 Simple parallel reactor

Publications (1)

Publication Number Publication Date
CN212855694U true CN212855694U (en) 2021-04-02

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