CN212790927U

CN212790927U - Extraction equipment of fosfomycin trometamol

Info

Publication number: CN212790927U
Application number: CN202021512172.4U
Authority: CN
Inventors: 曾媛媛
Original assignee: Keda Huacai Wuhan Biotechnology Co ltd
Current assignee: Keda Huacai Wuhan Biotechnology Co ltd
Priority date: 2020-07-27
Filing date: 2020-07-27
Publication date: 2021-03-26
Anticipated expiration: 2030-07-27

Abstract

The utility model discloses an extraction equipment of fosfomycin trometamol, including PMKD, PMKD's top fixed mounting has braced frame, and braced frame's top fixed mounting has fixed member, and one side fixed mounting of fixed member has solid fixed ring, and solid fixed ring's inside fixed mounting has the extraction box, and the bottom both sides of extraction box all communicate has pipeline, and pipeline's bottom fixed mounting has the experiment hydroextractor, and one side fixed mounting of experiment hydroextractor has driving motor, and the bottom fixed mounting of experiment hydroextractor has the processing case, and one side fixed mounting of processing case has the drawing liquid machine. Through setting up devices such as processing case, experiment hydroextractor and dump bin for to this material at the in-process that draws, handle the confined state all the time, avoid its reactant spill, produce the injury to the human body, simultaneously through setting up specific equipment, thereby can accelerate the drawing of material, improve holistic work efficiency.

Description

Extraction equipment of fosfomycin trometamol

Technical Field

The utility model belongs to the technical field of the medicine draws equipment, concretely relates to fosfomycin trometamol draw equipment.

Background

Fosfomycin trometamol is odorless and salty in taste; the specific rotation degree is measured by weighing the product with hygroscopicity, accurately weighing, dissolving in water to obtain solution containing 50mg per 1ml, and measuring according to the method to obtain specific rotation degree of-2.0 to-4.0.

For the extraction of common fosfomycin trometamol on the market, a large amount of materials are consumed integrally, and no specific equipment is needed during extraction, so that a human body is often in direct contact with the fosfomycin trometamol during work, and the fosfomycin trometamol is extremely easy to damage the human body in a long-time operation process, thereby not only harming the health of the human body, but also influencing the surrounding environment, and therefore people need to improve the situation.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a fosfomycin trometamol's extraction equipment to propose current extraction equipment in solving above-mentioned background art in the use, because expose for a long time outside, do not have specific equipment, thereby harm human problem easily in use.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a fosfomycin trometamol's equipment of drawing, includes PMKD, PMKD's top fixed mounting has braced frame, braced frame's top fixed mounting has fixed member, one side fixed mounting of fixed member has solid fixed ring, gu fixed ring's inside fixed mounting has the extraction box, the bottom both sides of extraction box all communicate there is pipeline, pipeline's bottom fixed mounting has the experiment hydroextractor, one side fixed mounting of experiment hydroextractor has driving motor, the bottom fixed mounting of experiment hydroextractor has the processing case, one side fixed mounting who handles the case has the drawing liquid machine, the top intercommunication of drawing liquid machine has the connecting tube, the bottom fixed mounting of connecting tube has the collecting box.

Preferably, the equal fixed mounting in top both sides of extraction box has first blowing pipe, braced frame's inside fixed mounting has the second fixed plate, the top fixed mounting of second fixed plate has the dump bin.

Preferably, the inside fixed mounting of braced frame has first fixed plate, the top intercommunication of experiment hydroextractor has the filling tube, the one side intercommunication of handling the case has the second blowing pipe, the specification and size looks adaptation of solid fixed ring and extraction box.

Preferably, the inside fixed mounting of collecting box has fixed spout, the inside fixed mounting of fixed spout has the filter vat, the inside fixed mounting of filter vat has the filter screen, the bottom movable mounting of filter vat has the collection box.

Preferably, the collecting box is located under the filtering barrel, the bottom of the collecting box is fixedly provided with an anti-slip pad and an adsorption net, and the outside of the collecting box is fixedly provided with a switch door.

Preferably, the bottom of the fixed bottom plate is fixedly provided with a rolling wheel.

Compared with the prior art, the beneficial effects of the utility model are that:

the device comprises a treatment box, an experimental dehydrator, a waste material box and the like, wherein the treatment box is used for treating a closed state all the time in the extraction process of the substance, so that the reactant is prevented from splashing and causing harm to a human body; the three wastes generated by the reaction are few, and almost no wastewater is generated, so that the integral extraction is more efficient.

Drawings

Fig. 1 is a schematic front view of the three-dimensional structure of the present invention;

fig. 2 is a schematic diagram of a rear perspective structure of the present invention;

fig. 3 is a schematic sectional view of the filtering apparatus of the present invention.

In the figure: 1. fixing the bottom plate; 2. a support frame; 3. a treatment tank; 4. a liquid pumping machine; 5. connecting a pipeline; 6. a collection box; 7. opening and closing the door; 8. a first fixing plate; 9. a drive motor; 10. an experimental dehydrator; 11. a feed tube; 12. a delivery conduit; 13. fixing the rod piece; 14. a fixing ring; 15. an extraction box; 16. a waste bin; 17. a second fixing plate; 18. fixing the chute; 19. a filter vat; 20. a filter screen; 21. a collection box; 22. a first discharge pipe; 23. a second discharge pipe.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: the utility model provides a fosfomycin trometamol's equipment of drawing, including PMKD 1, PMKD 1's top fixed mounting has braced frame 2, braced frame 2's top fixed mounting has fixed rod piece 13, one side fixed mounting of fixed rod piece 13 has solid fixed ring 14, gu fixed ring 14's inside fixed mounting has extraction box 15, extraction box 15's bottom both sides all communicate there is pipeline 12, pipeline 12's bottom fixed mounting has experiment hydroextractor 10, one side fixed mounting of experiment hydroextractor 10 has driving motor 9, the bottom fixed mounting of experiment hydroextractor 10 has treatment box 3, one side fixed mounting of treatment box 3 has extractor 4, the top intercommunication of extractor 4 has connecting tube 5, connecting tube 5's bottom fixed mounting has collecting box 6.

In the embodiment, a supporting frame 2 is fixedly arranged at the top of a fixed bottom plate 1, so that the whole device can be conveniently fixed, a fixed rod 13 is fixedly arranged at the top of the supporting frame 2, a fixed ring 14 is fixedly arranged at one side of the fixed rod 13, so that the extraction box 15 can be more firmly fixed, conveying pipelines 12 are communicated with two sides of the bottom of the extraction box 15, so that the extracted substances can be conveniently classified and the experiment can be conveniently carried out, an experiment dehydrator 10 is fixedly arranged at the bottom of the conveying pipeline 12, so that the vacuum dehydration operation can be conveniently carried out on the product after the experiment, a treatment box 3 is fixedly arranged at the bottom of the experiment dehydrator 10, so that the secondary operation can be conveniently carried out on the treated substances, the integral purity is improved, a liquid pumping machine 4 is fixedly arranged at one side of the treatment box 3, and the top of the liquid pumping machine 4 is communicated with a connecting pipeline 5, be convenient for carry out the secondary experiment operation to the material after handling, further improve holistic purity, to connecting tube 5's bottom fixed mounting have collecting box 6, be convenient for collect the processing to the material after handling.

Specifically, first discharging pipes 22 are fixedly mounted on two sides of the top of the extraction box 15, a second fixing plate 17 is fixedly mounted inside the supporting frame 2, and a waste box 16 is fixedly mounted on the top of the second fixing plate 17.

In this embodiment, through the equal fixed mounting in top both sides of extraction box 15 has first blowing pipe 22, is convenient for add the material of different ratios, has second fixed plate 17 to the inside fixed mounting of braced frame 2 to and the top fixed mounting of second fixed plate 17 has waste bin 16, makes waste bin 16's fixed more firm.

Specifically, the inside fixed mounting of braced frame 2 has first fixed plate 8, and the top intercommunication of experiment hydroextractor 10 has filling tube 11, and one side intercommunication of handling case 3 has second blowing pipe 23, and the specification and size looks adaptation of solid fixed ring 14 and extraction box 15.

In this embodiment, there is first fixed plate 8 through braced frame 2's inside fixed mounting, is convenient for support experiment hydroextractor 10, has filling tube 11 to the top intercommunication of experiment hydroextractor 10, is convenient for add the material, has second blowing pipe 23 to the one side intercommunication of handling case 3, also is convenient for add the material, to the specification and size looks adaptation of solid fixed ring 14 and extraction box 15 for holistic fixed more firm.

Specifically, a fixed chute 18 is fixedly mounted inside the collecting box 6, a filtering barrel 19 is fixedly mounted inside the fixed chute 18, a filtering net 20 is fixedly mounted inside the filtering barrel 19, and a collecting box 21 is movably mounted at the bottom of the filtering barrel 19.

In this embodiment, there is fixed spout 18 through the inside fixed mounting of collecting box 6 for filter vat 19 is fixed more firmly, has filter screen 20 through filter vat 19's inside fixed mounting, can carry out filtering operation to all the other materials, improves the purity that wholly draws, has collection box 21 to filter vat 19's bottom movable mounting, is convenient for collect the material.

Specifically, the collecting box 21 is located under the filtering barrel 19, the bottom of the collecting box 21 is fixedly provided with an anti-slip pad and an adsorption net, and the outside of the collecting box 6 is fixedly provided with the switch door 7.

In this embodiment, be located filter vat 19 through collecting box 21 under to and the bottom fixed mounting who collects box 21 has slipmat and adsorption net, makes the collection to fosfomycin tromethamine more convenient on the one hand, and on the other hand can avoid its unrestrained liquid to corrode to the inside production of instrument, has switch door 7 to the outside fixed mounting of collecting box 6, is convenient for collect the material after drawing.

Specifically, the bottom of the fixed bottom plate 1 is fixedly provided with a rolling wheel.

In this embodiment, the bottom fixed mounting through PMKD 1 has the wheel that rolls for the holistic removal of device is more convenient.

The utility model discloses a theory of operation and use flow: when in use, firstly, levo-fosfomycin dextrophenethylamine salt and an alkali metal hydroxide aqueous solution are respectively put in two first discharging pipes 22 according to the proportion, the levo-fosfomycin dextrophenethylamine salt and the alkali metal hydroxide aqueous solution are put in an extraction box 15 and then are reacted with each other to enable the levo-phenethylamine to be dissociated, then the left-phenethylamine is kept still for a period of time, so that the levo-fosfomycin dialkali metal salt aqueous solution can be obtained from the extraction box 15, a conveying pipeline 12 is opened to enable the fosfomycin dialkali metal salt aqueous solution to fall into an experimental dehydrator 10, at the moment, a tromethamine acid inorganic acid salt aqueous solution can be added into the experiment dehydrator through a feeding pipe 11, at the moment, a driving motor 9 is started to enable the experimental dehydrator 10 to start to operate, reactants in the experiment dehydrator are subjected to vacuum concentration and dehydration until the reactants are dried to obtain mixed salt, the mixed salt is, adding methanol into the fosfomycin trometamol solution to dissolve the fosfomycin trometamol, namely mixed salt, arranging a liquid extractor 4 on one side of the liquid extractor 4, arranging a filter screen 20 in a pipeline connected with one end of the liquid extractor 4, filtering to remove inorganic alkali metal salt, conveying the rest substances into a collecting box 6, adding a polar organic solvent into filtrate for dilution to separate out the fosfomycin trometamol solution, and carrying out secondary filtering operation on the filtrate, wherein the filtered substances fall into a first discharging pipe 22 through the filter screen 20, at the moment, the fosfomycin trometamol is extracted, and when the solid is needed, the filtrate is dried again, so that the fosfomycin trometamol is extracted by the method, the raw materials are cheap and easy to obtain, the toxicity is low, the cost is low, and the method is suitable for industrial mass production; and the generated three wastes are less, almost no waste water is generated, and the method is the best extraction measure.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a fosfomycin trometamol's extraction equipment, includes PMKD (1), its characterized in that: the top of the fixed bottom plate (1) is fixedly provided with a supporting frame (2), the top of the supporting frame (2) is fixedly provided with a fixed rod piece (13), one side of the fixed rod piece (13) is fixedly provided with a fixed ring (14), the interior of the fixed ring (14) is fixedly provided with an extraction box (15), both sides of the bottom of the extraction box (15) are communicated with a conveying pipeline (12), the bottom of the conveying pipeline (12) is fixedly provided with an experimental dehydrator (10), a driving motor (9) is fixedly arranged on one side of the experimental dehydrator (10), the bottom of the experimental dehydrator (10) is fixedly provided with a processing box (3), a liquid pumping machine (4) is fixedly arranged on one side of the treatment box (3), the top of the liquid pumping machine (4) is communicated with a connecting pipeline (5), and a collecting box (6) is fixedly arranged at the bottom of the connecting pipeline (5).

2. The extraction apparatus of fosfomycin trometamol according to claim 1, characterized in that: the equal fixed mounting in top both sides of extraction box (15) has first blowing pipe (22), the inside fixed mounting of braced frame (2) has second fixed plate (17), the top fixed mounting of second fixed plate (17) has dump bin (16).

3. The extraction apparatus of fosfomycin trometamol according to claim 1, characterized in that: the inside fixed mounting of braced frame (2) has first fixed plate (8), the top intercommunication of experiment hydroextractor (10) has charge-in tube (11), the one side intercommunication of handling case (3) has second blowing pipe (23), the specification and size looks adaptation of the specification and the extraction box (15) of solid fixed ring (14).

4. The extraction apparatus of fosfomycin trometamol according to claim 1, characterized in that: the collecting box is characterized in that a fixed chute (18) is fixedly arranged in the collecting box (6), a filter barrel (19) is fixedly arranged in the fixed chute (18), a filter screen (20) is fixedly arranged in the filter barrel (19), and a collecting box (21) is movably arranged at the bottom of the filter barrel (19).

5. The extraction apparatus of fosfomycin trometamol according to claim 4, characterized in that: the collecting box (21) is positioned under the filtering barrel (19), the bottom of the collecting box (21) is fixedly provided with an anti-skid pad and an adsorption net, and the outside of the collecting box (6) is fixedly provided with a switch door (7).

6. The extraction apparatus of fosfomycin trometamol according to claim 1, characterized in that: the bottom of the fixed bottom plate (1) is fixedly provided with a rolling wheel.