CN212780209U

CN212780209U - Liquid extraction device and device for liquid dilution

Info

Publication number: CN212780209U
Application number: CN202021158899.7U
Authority: CN
Inventors: 朱俐; 赵瑜; 尹利辉; 许明哲; 姚尚辰
Original assignee: National Institutes for Food and Drug Control
Current assignee: National Institutes for Food and Drug Control
Priority date: 2020-06-19
Filing date: 2020-06-19
Publication date: 2021-03-23
Anticipated expiration: 2030-06-19

Abstract

The utility model relates to a liquid detects technical field, especially relates to a liquid extraction element, and it includes: the liquid suction pipe is used for sucking liquid; the bottom of the liquid transferring device is communicated with the liquid transferring device through the first one-way valve, so that liquid can enter the liquid transferring device through the liquid transferring device and the first one-way valve; and the second one-way valve is communicated with the bottom of the pipettor, so that liquid in the pipettor can be discharged through the second one-way valve. When liquid is sucked, the liquid transfer device is operated, the liquid can enter the liquid transfer device along the liquid transfer device and the first one-way valve, and the first one-way valve is closed; when it is desired to expel the extracted liquid, the pipette is operated, liquid can flow out of the second one-way valve, and the first one-way valve is closed. Therefore, a large amount of complicated operation work is not needed in the whole extraction process, the operation is simple, the consumed time is short, and the liquid collection efficiency is obviously improved. The present disclosure also provides a device for dilution of a liquid.

Description

Liquid extraction device and device for liquid dilution

Technical Field

The present disclosure relates to the field of liquid detection technology, and more particularly, to a liquid extraction device and a device for diluting liquid.

Background

Ion Mobility Spectrometry (IMS) is a novel detection technology, and is very suitable for rapidly detecting illegally added chemical substances in health-care food on site due to rapidness, high sensitivity and miniaturization. Before IMS on-site rapid detection is adopted, samples generally need to be subjected to pretreatment steps such as extraction, filtration, dilution and constant volume, sample introduction from low concentration to high concentration is followed during detection, if sample introduction concentration is too high, an instrument can be caused to generate memory effect, not only is the next detection result influenced, but also the cleaning is required for a long time and is difficult to clean, and therefore the samples need to be diluted by a certain multiple after extraction and filtration to start sample introduction detection.

However, the extraction and dilution of the sample liquid are currently performed by a large number of glassware such as conventional beakers, volumetric flasks, pipettes and droppers. Therefore, a large number of experimental devices are needed in the detection field, the operation process is complex, the consumed time is long, and the rapid detection in the field cannot be carried out at all.

SUMMERY OF THE UTILITY MODEL

The utility model provides a liquid extraction element and be used for the device of liquid dilution, the utility model discloses a purpose is in the efficiency that improves extraction liquid.

The liquid extraction device includes: the liquid suction pipe is used for sucking liquid; the bottom of the liquid transferring device is communicated with the liquid transferring device through the first one-way valve, so that liquid can enter the liquid transferring device through the liquid transferring device and the first one-way valve; and the second one-way valve is communicated with the bottom of the pipettor, so that liquid in the pipettor can be discharged through the second one-way valve.

According to some embodiments of the invention, the first one-way valve comprises a first housing having a first cavity, the first housing being located between the pipettor and the pipette; the top of the first cavity is communicated with the bottom of the liquid transferring device; a first gasket and a spherical first valve core are further arranged in the first cavity, and the first valve core is positioned between the pipettor and the first gasket; the first gasket is provided with a first through hole, and the first cavity is communicated with the liquid suction pipe through the first through hole; the top of the first cavity is provided with a first baffle plate for limiting the first valve core, and the first baffle plate is provided with a plurality of pore channels.

According to some embodiments of the invention, the surface of the first gasket facing the first valve element is provided as a cambered surface.

According to some embodiments of the invention, the second one-way valve comprises a second housing connected to the first housing; the second shell is provided with a liquid inlet flow channel, a second cavity and a liquid outlet flow channel; the liquid inlet flow channel is communicated with the first cavity, and the liquid inlet flow channel and the liquid outlet flow channel are positioned at two opposite sides of the second cavity, so that liquid entering the second cavity from the first cavity can be discharged from the liquid outlet flow channel; a second gasket and a spherical second valve core are arranged in the second cavity, and the second gasket is positioned between the liquid inlet flow channel and the second valve core; the second gasket is provided with a second through hole, and the second cavity is communicated with the liquid inlet flow channel through the second through hole; a second baffle plate for limiting the second valve core is arranged between the liquid outlet flow channel and the second cavity, and a plurality of pore channels are arranged on the second baffle plate.

According to some embodiments of the invention, the surface of the second gasket facing the second valve element is provided as a cambered surface.

According to some embodiments of the present invention, the liquid dispenser further comprises a filtering tube, a top of the filtering tube being detachably connected to the end of the liquid suction tube; the filter pipe comprises a suction pipe and a filter head, and the filter head is positioned between the suction pipe and the suction pipe so that liquid enters the suction pipe through the suction pipe and the filter head; the filter head is internally provided with a filter membrane for filtering solid particles.

According to some embodiments of the present invention, the pipette comprises a syringe, a bottom of the syringe being in communication with the pipette through the first one-way valve; the syringe comprises a cylinder body and a piston rod; a limiting piece is arranged in the cylinder body to limit the stroke of the piston rod in the cylinder body.

According to some embodiments of the invention, the liquid container further comprises a liquid container, the pipette being communicable with the liquid container such that the pipette can aspirate liquid from the liquid container.

According to some embodiments of the present invention, the liquid container includes a container body and a sealing cover, and the pipette is movably inserted into the sealing cover so as to communicate with the container body; the container body and the sealing cover are detachably connected.

The device for diluting liquid comprises a dilution container and the liquid extraction device of any one of the embodiments, wherein the second one-way valve is communicated with the dilution container, so that liquid in the pipettor can be discharged into the dilution container through the second one-way valve.

The embodiment of the utility model provides a technical scheme compares with prior art and has following advantage:

when liquid is sucked, the liquid transfer device is operated, the liquid can enter the liquid transfer device along the liquid transfer device and the first one-way valve, and the first one-way valve is closed; when it is desired to expel the extracted liquid, the pipette is operated, liquid can flow out of the second one-way valve, and the first one-way valve is closed. Therefore, a large amount of complicated operation work is not needed in the whole extraction process, the operation is simple, the consumed time is short, and the efficiency of extracting liquid is obviously improved.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present disclosure and together with the description, serve to explain the principles of the disclosure.

In order to more clearly illustrate the embodiments or technical solutions in the prior art of the present disclosure, the drawings used in the description of the embodiments or prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without inventive exercise.

FIG. 1 is a schematic view of an apparatus for dilution of a liquid according to an embodiment of the present invention;

fig. 2 is a schematic view of a first check valve and a second check valve according to an embodiment of the present invention.

Wherein, 1, a pipette; 2. a pipettor; 3. a first check valve; 4. a second one-way valve; 5. a first housing; 6. a first cavity; 7. a first gasket; 8. a first valve spool; 9. a first through hole; 10. a first fence; 11. a second housing; 12. a second cavity; 13. a liquid inlet flow channel; 14. A liquid outlet flow passage; 15. a second gasket; 16. a second valve core; 17. a second through hole; 18. a second fence; 19. a filter tube; 20. a straw; 21. a filter head; 22. a barrel; 23. a piston rod; 24. a limiting member; 25. a liquid container; 26. a container body; 27. a sealing cover; 28. a seal ring; 29. a dilution vessel; 30. a conduit.

Detailed Description

In order that the above objects, features and advantages of the present disclosure may be more clearly understood, aspects of the present disclosure will be further described below. It should be noted that the embodiments and features of the embodiments of the present disclosure may be combined with each other without conflict.

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present disclosure, but the present disclosure may be practiced in other ways than those described herein; it is to be understood that the embodiments disclosed in the specification are only a few embodiments of the present disclosure, and not all embodiments.

As shown in fig. 1, the utility model provides a liquid extraction device, it includes pipette 1, pipettor 2, first check valve 3 and second check valve 4. The pipette 1 is used to aspirate liquid. The bottom of the pipette 2 communicates with the pipette 1 through the first check valve 3 so that liquid can enter the pipette 2 from through the pipette 1 and the first check valve 3. The second one-way valve 4 communicates with the bottom of the pipette 2 so that liquid in the pipette 2 can be discharged through the second one-way valve 4.

In this embodiment, when it is required to extract liquid, the pipette 2 is operated first, and the liquid can be sucked into the pipette 1, from the pipette 1 into the first one-way valve 3, from the first one-way valve 3 into the pipette 2, and during this time the second one-way valve 4 is closed. Then, the pipette 2 is operated again, and the liquid in the pipette 2 can enter the second check valve 4 and be discharged through the second check valve 4, and the first check valve 3 is closed all the time. Of course, any container may be used to receive the liquid discharged from the second check valve 4. Therefore, a large amount of complicated operation work is not needed in the whole extraction process, the operation is simple, the consumed time is short, and the efficiency of extracting liquid is obviously improved. And the liquid extraction device can be carried to a detection site at any time for use, while the traditional detection mode can only be carried out in a laboratory by means of a large amount of glassware. In addition, the liquid extraction device can be widely applied to the field of liquid detection, particularly the field of mobility spectrometry detection.

In this embodiment, the pipette 1, the first check valve 3, and the second check valve 4 may all be fixed to the pipette 2, both improving the integration of the entire apparatus and facilitating carrying. And whole device is better for traditional uncovered glass container, and the leakproofness has avoided causing the injury to the experimenter because of liquid volatilizees.

It should be noted that, the pipettor 2, the first check valve 3 and the second check valve 4 are devices conventional in the art, and the present invention is not described in detail for the structures and functions of these conventional devices.

As shown in fig. 2, in some embodiments of the present invention, the first one-way valve 3 comprises a first housing 5 having a first cavity 6, the first housing 5 being located between the pipette 2 and the pipette 1. The top of the first cavity 6 communicates with the bottom of the pipette 2. The first cavity 6 is also provided with a first gasket 7 and a first ball-shaped valve core 8, and the first valve core 8 is positioned between the pipettor 2 and the first gasket 7. The first gasket 7 has a first through hole 9, and the first cavity 6 communicates with the pipette 1 through the first through hole 9. The top of the first cavity 6 is provided with a first baffle 10 for limiting the first valve core 8, and the first baffle 10 is provided with a plurality of pore channels.

In this embodiment, the first gasket 7 is preferably arranged at the bottom of the first cavity 6. In a natural state, the first valve element 8 stays at the first through hole 9 temporarily due to gravity, and blocks the first through hole 9. When the liquid transfer device 2 sucks liquid, the liquid flows to the first cavity 6 through the liquid transfer device 1; when the liquid flows to the first through hole 9, the first valve core 8 is jacked up and continues to flow to the pipette 2. When the pipette 2 discharges the liquid, the liquid presses the first valve element 8 tightly against the first gasket 7 and blocks the first through hole 9, blocking the liquid from flowing down from the first through hole 9. The liquid does not leak during the discharge of the liquid from the pipette 2.

In this embodiment, the first baffle 10 may limit the first valve element 8 from moving toward the pipette 2, so as to prevent the first valve element 8 from blocking the channel between the first cavity 6 and the pipette 2.

As shown in fig. 2, in some embodiments of the present invention, the surface of the first gasket 7 facing the first valve element 8 is provided as a curved surface. In this embodiment, the surface of the first valve element 8 may be attached to the arc surface of the first gasket 7, thereby improving the sealing performance of the first check valve 3. Of course, the curved surface is preferably arranged to conform to the surface of the first spool 8.

As shown in fig. 2, in some embodiments of the present invention, the second check valve 4 includes a second housing 11, and the second housing 11 is connected to the first housing 5; the second shell 11 is provided with a liquid inlet flow channel 13, a second cavity 12 and a liquid outlet flow channel 14; the liquid inlet flow channel 13 is communicated with the first cavity 6, and the liquid inlet flow channel 13 and the liquid outlet flow channel 14 are positioned at two opposite sides of the second cavity 12, so that the liquid entering the second cavity 12 from the first cavity 6 can be discharged from the liquid outlet flow channel 14; a second gasket 15 and a spherical second valve core 16 are arranged in the second cavity 12, and the second gasket 15 is positioned between the liquid inlet flow channel 13 and the second valve core 16; the second gasket 15 is provided with a second through hole 17, and the second cavity 12 is communicated with the liquid inlet flow channel 13 through the second through hole 17; a second baffle plate 18 for limiting the second valve core 16 is arranged between the liquid outlet flow passage 14 and the second cavity 12, and a plurality of pore passages are arranged on the second baffle plate 18.

In this embodiment, when the pipette 2 aspirates liquid, the second valve core 16 is pressed tightly against the second gasket 15 by the pipette 2, and blocks the second through hole 17, so as to block the liquid from flowing out of the second through hole 17. The liquid will not leak during pumping of the liquid. When the liquid is discharged from the pipette 2, the liquid flows toward the liquid inlet channel 13, and the liquid pushes the second valve element 16 away at the second through hole 17, so that the liquid can enter the second cavity 12 and be discharged from the liquid outlet channel 14.

In this embodiment, second check valve 4 and first check valve 3 can be in the same place through screw connection to be in the same place these two check valves are integrated, both conveniently dismantle the washing, also conveniently carry.

In this embodiment, the second baffle 18 limits the second valve element 16 from moving toward the liquid outlet channel 14, so as to prevent the second valve element 16 from blocking the passage between the second cavity 12 and the pipette 2.

As shown in fig. 2, in some embodiments of the present invention, the surface of the second gasket 15 facing the second valve element 16 is provided as a curved surface. In this embodiment, the surface of the second spool 16 may be attached to the arc surface of the second gasket 15, thereby improving the sealability of the second check valve 4. Of course, the camber is preferably configured to conform to the surface of the second spool 16.

As shown in fig. 1, in some embodiments of the present invention, the liquid extraction device further comprises a filter tube 19, and the top of the filter tube 19 is detachably connected to the end of the pipette 1. The filter tube 19 includes a pipette 20 and a filter 21, the filter 21 being positioned between the pipette 1 and the pipette 20 to allow liquid to enter the pipette 1 through the pipette 20 and the filter 21. The filter head 21 is provided therein with a filter membrane for filtering solid particles.

In this embodiment, the filtering pipe 19 can be lengthened by the length of the pipette 1, and the filtering pipe 19 can be replaced as needed. The filter membrane in the filter head 21 can filter solid particles in the liquid to prevent contaminants from contaminating the instrument. Of course, the straw 20 and the filter head 21 are preferably provided as an integral molding.

As shown in fig. 1, in some embodiments of the present invention, the pipette 2 comprises a syringe, the bottom of which communicates with the pipette 1 through a first one-way valve 3. The syringe comprises a barrel 22 and a plunger rod 23. A stopper 24 is provided in the cylinder 22 to limit the stroke of the piston rod 23 in the cylinder 22.

In the present embodiment, the limit member 24 limits the stroke of the piston rod 23, so that the syringe can suck a fixed amount of liquid each time, which facilitates dilution of the fixed amount of liquid (for example, the volume of liquid sucked each time can be kept consistent, and the dilution ratio can be kept consistent), and the piston rod 23 can be prevented from being pulled out. The stopper 24 may be a protrusion, a stopper, or the like provided in the cylinder 22, or may be a screw or the like penetrating the cylinder 22.

As shown in fig. 1, in some embodiments of the present invention, the liquid extraction device further comprises a liquid container 25, and the pipette 1 may be in communication with the liquid container 25, so that the pipette 1 may aspirate liquid from the liquid container 25.

In this embodiment, the liquid container 25 may contain an extraction reagent therein and dissolve a food sample or a drug sample using the extraction reagent. The pipette 1 can absorb the supernatant of the mixed liquid in the liquid container 25.

As shown in fig. 1, in some embodiments of the present invention, the liquid container 25 includes a container body 26 and a sealing cap 27, and the pipette 1 is movably inserted into the sealing cap 27 so that the pipette 1 communicates with the container body 26. The container body 26 and the sealing lid 27 are detachably connected.

In this embodiment, the sealing cap 27 may be provided with a through-hole through which the pipette 1 may pass and extend into the container body 26. A sealing ring 28 may be provided in the through-going hole to seal the gap between the pipette 1 and the sealing cap 27. In order to prevent the extraction solvent from leaking or volatilizing from the connection between the pipette 1 and the pipette 20 (i.e., to prevent injury to the laboratory worker), the filter tube 19 is preferably provided in the container body 26.

As shown in fig. 1, the present invention further provides a device for diluting liquid, which comprises a dilution container 29 and the liquid extraction device of any of the above embodiments, wherein the second check valve 4 is communicated with the dilution container 29, so that the liquid in the pipette 2 can be discharged into the dilution container 29 through the second check valve 4.

In this embodiment, the dilution container 29 may contain a dilution solvent, and the liquid extracted by the liquid extraction device may be discharged into the dilution container 29 for dilution and further detection. The dilution vessel 29 may be in communication with the second one-way valve 4 (specifically, the outlet flow channel 14 of the second one-way valve 4) via a conduit 30.

The method of using the liquid extraction device or the device for diluting a liquid will be described with reference to fig. 1 and 2.

(1) The sealing cover 27 is taken down, and the pipette 1, the pipette 2, the filter tube 19 and the dilution container 29 are installed;

(2) placing the sample to be tested in a liquid container 25 and adding an extraction reagent; covering the sealing cover 27, and then oscillating and standing for a period of time;

(3) the piston rod 23 is pulled upwards, and the supernatant in the liquid container 25 is extracted into the liquid transfer device 2 through the first one-way valve 3; then the piston rod 23 is pushed downwards, and the liquid in the liquid transfer device 2 is pushed into the dilution container 29 through the second one-way valve 4;

(4) the dilution vessel 29 is removed and the diluted solution in the dilution vessel 29 is tested (e.g., ion mobility spectrometry monitoring).

It is noted that, in this document, relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.

The foregoing are merely exemplary embodiments of the present disclosure, which enable those skilled in the art to understand or practice the present disclosure. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the disclosure. Thus, the present disclosure is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A liquid extraction device, comprising:

a pipette (1), the pipette (1) being for aspirating a liquid;

a liquid transfer device (2), wherein the bottom of the liquid transfer device (2) is communicated with the liquid transfer device (1) through a first one-way valve (3), so that liquid can enter the liquid transfer device (2) from the liquid transfer device (1) and the first one-way valve (3); and

a second one-way valve (4), the second one-way valve (4) being in communication with the bottom of the pipette (2) such that liquid in the pipette (2) can be expelled through the second one-way valve (4).

2. The liquid extraction device according to claim 1, characterized in that the first one-way valve (3) comprises a first housing (5) with a first cavity (6), the first housing (5) being located between the pipette (2) and the pipette (1);

the top of the first cavity (6) is communicated with the bottom of the liquid transfer device (2); a first gasket (7) and a first spherical valve core (8) are further arranged in the first cavity (6), and the first valve core (8) is located between the pipette (2) and the first gasket (7); the first gasket (7) is provided with a first through hole (9), and the first cavity (6) is communicated with the liquid suction pipe (1) through the first through hole (9);

the top of the first cavity (6) is provided with a first baffle plate (10) for limiting the first valve core (8), and the first baffle plate (10) is provided with a plurality of pore channels.

3. Liquid extraction device according to claim 2, characterized in that the surface of the first gasket (7) facing the first valve spool (8) is arranged as a cambered surface.

4. Liquid extraction device according to claim 2, characterized in that the second one-way valve (4) comprises a second housing (11), the second housing (11) being connected with the first housing (5);

the second shell (11) is provided with a liquid inlet flow passage (13), a second cavity (12) and a liquid outlet flow passage (14); the liquid inlet flow channel (13) is communicated with the first cavity (6), and the liquid inlet flow channel (13) and the liquid outlet flow channel (14) are positioned at two opposite sides of the second cavity (12), so that liquid entering the second cavity (12) from the first cavity (6) can be discharged from the liquid outlet flow channel (14);

a second gasket (15) and a second ball valve core (16) are arranged in the second cavity (12), and the second gasket (15) is positioned between the liquid inlet flow channel (13) and the second valve core (16); the second gasket (15) is provided with a second through hole (17), and the second cavity (12) is communicated with the liquid inlet flow channel (13) through the second through hole (17);

a second baffle plate (18) for limiting the second valve core (16) is arranged between the liquid outlet flow channel (14) and the second cavity (12), and a plurality of pore channels are arranged on the second baffle plate (18).

5. Liquid extraction device according to claim 4, characterized in that the surface of the second gasket (15) facing the second valve spool (16) is arranged as a cambered surface.

6. The liquid extraction apparatus according to claim 1, further comprising a filter tube (19), a top of the filter tube (19) being detachably connected to a distal end of the pipette (1);

the filter tube (19) comprises a suction tube (20) and a filter head (21), the filter head (21) is positioned between the suction tube (1) and the suction tube (20) so as to make liquid enter the suction tube (1) through the suction tube (20) and the filter head (21);

and a filter membrane for filtering solid particles is arranged in the filter head (21).

7. The liquid extraction device according to claim 1, characterized in that the pipette (2) comprises a syringe, the bottom of which communicates with the pipette (1) through the first one-way valve (3); the syringe comprises a barrel (22) and a piston rod (23); a limiting piece (24) is arranged in the cylinder body (22) to limit the stroke of the piston rod (23) in the cylinder body (22).

8. Liquid extraction device according to claim 1, further comprising a liquid container (25), the pipette (1) being communicable with the liquid container (25) such that the pipette (1) can aspirate liquid from the liquid container (25).

9. The liquid extraction apparatus according to claim 8, wherein the liquid container (25) includes a container body (26) and a sealing cap (27), and the pipette (1) is movably inserted into the sealing cap (27) to communicate the pipette (1) with the container body (26); the container body (26) and the sealing cover (27) are detachably connected.

10. A device for dilution of a liquid, comprising a dilution vessel (29) and a liquid extraction device according to any one of claims 1 to 9, the second one-way valve (4) being in communication with the dilution vessel (29) such that liquid in the pipette (2) can be expelled through the second one-way valve (4) into the dilution vessel (29).