CN212730584U - Heart perfusion device - Google Patents

Abstract

The utility model relates to a heart perfusion device, infusion capital portion sets up the infusion bottle peg that both ends have the couple respectively, it has infusion bag to hang on the couple, the lift adjustment rope is connected at the infusion bag top and realize altitude mixture control in stretching into the fixed through-hole of different positions through the dead lever that sets up on the lift adjustment rope, infusion bag intercommunication has the infusion hose of syringe needle and drip kettle, set up the velocity of flow regulator on the infusion hose, place the monitoring box that is equipped with intelligent detection module on the base, host system and weighing module, lighting module, alarm module, display module and power module are connected, host system passes through wireless communication module and customer end and host computer connection, still set up on the base and paste the strip. The utility model provides a heart perfusion device is applicable to heart and the vascular infusion liquid to laboratory mouse, washs the blood vessel to last section detects, defeated PBS solution earlier, defeated stationary liquid again, and the speed of filling is adjustable, and each organ of protection laboratory mouse, tissue etc. do not receive the harm, realize intellectuality.

Description

Heart perfusion device

Technical Field

The utility model belongs to the technical field of medical equipment, concretely relates to heart perfusion device.

Background

In modern medical, pharmaceutical and toxicological experiments, researchers usually perform animal experiments to simulate various physiological phenomena and pathogenesis of human beings, and reasonably clarify and verify the physiological phenomena and pathogenesis. The blood circulation system in the laboratory mouse can be thoroughly cleaned through the heart perfusion device, and the influence of the existing blood or blood components thereof on the subsequent experimental research results is reduced. Most of the heart perfusion devices that use at present only use a transfusion bottle or infusion bottle to carry out the perfusate, fill PBS solution (normal saline) to the experimental mouse internal earlier, reuse same transfusion bottle perfusion stationary liquid after finishing, device simple structure, the function is single, can't be according to actual mouse position control transfusion bottle height, the operation portability is poor.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problems existing in the prior art, the present invention aims to provide a heart perfusion device.

In order to realize the above purpose, reach above-mentioned technological effect, the utility model discloses a technical scheme be:

the utility model provides a heart perfusion device, including the infusion support body, the infusion support body includes base and the vertical infusion post of placing, base and infusion post are placed perpendicularly mutually, infusion capital portion sets up the infusion bottle peg that both ends have the couple respectively, hang infusion bag on the couple, vertically set up a plurality of fixed through-hole that is used for adjusting infusion bag height on the infusion post, infusion bag top connection lift adjustment rope and through the fixed pole that sets up on the lift adjustment rope stretch into the fixed through-hole of different positions in realizing the altitude mixture control, infusion bag intercommunication has the infusion hose of syringe needle and drip cup, the syringe needle injects the heart of laboratory mouse, infuse the liquid to the laboratory mouse internal through the infusion hose, set up the velocity of flow regulator on the infusion hose, detachable the monitoring box who is equipped with intellectual detection system module of placing on the base, intellectual detection system module includes main control module, weigh the module, illumination module, the intellectual, Alarm module, display module, wireless communication module and power module, host system with weigh module, lighting module, alarm module, display module and power module and be connected, host system passes through wireless communication module and customer end and host computer connection, carries out two-way communication, still sets up the pasting strip of a plurality of respectively with the neck portion and the four limbs one-to-one of laboratory mouse on the base.

Furthermore, the storage box is detachably mounted on the base through bolts, and the front opening and the rear opening of the storage box are formed.

Furthermore, the storage box is made of transparent plastics, and a plurality of hollow holes are formed in the left side wall and the right side wall of the storage box.

Further, the monitoring box is detachably installed on the base through bolts, is of a hollow structure, and the lighting module is an LED lamp and is placed at the top of the monitoring box.

Furthermore, the main control module is a single chip microcomputer or a PLC, the weighing module is an electronic scale, the alarm module is a buzzer, the display module is an LED liquid crystal display screen, the wireless communication module is a 4G, 5G, Wi-Fi, Bluetooth or Zigbee module, and the power supply module is a solar cell panel.

Further, a layer of rubber pad is laid on the base.

Further, the thickness of the rubber pad is 1-5 mm.

Furthermore, a U-shaped drainage diversion groove is formed in the base, and waste liquid flows into an external waste liquid bottle communicated with the drainage diversion groove through the drainage diversion groove.

Compared with the prior art, the beneficial effects of the utility model are that:

the utility model discloses a heart perfusion device, which comprises a transfusion bracket body, wherein the transfusion bracket body comprises a base and a vertically arranged transfusion column, the base and the transfusion column are mutually and vertically arranged, the top of the transfusion column is provided with a transfusion bottle hanging rod with hooks at two ends respectively, a transfusion bag is hung on the hooks, a plurality of fixing through holes for adjusting the height of the transfusion bag are longitudinally arranged on the transfusion column, the top of the transfusion bag is connected with a lifting adjusting rope and extends into the fixing through holes at different positions through the fixing rod arranged on the lifting adjusting rope to realize the height adjustment, the transfusion bag is communicated with a transfusion hose with a needle head and a drip cup, the needle head is inserted into the heart of a laboratory mouse, the transfusion body is perfused into the laboratory mouse through the transfusion hose, the waste liquid can be discharged into a waste liquid bottle through a drainage guide groove on the base, the transfusion hose is provided with a flow rate regulator, the intelligent detection module comprises a main control module, a weighing module, an illuminating module, an alarming module, a display module, a wireless communication module and a power supply module, wherein the main control module is connected with the weighing module, the illuminating module, the alarming module, the display module and the power supply module, the main control module is connected with a client and an upper computer through the wireless communication module to perform two-way communication, and a plurality of sticking strips which correspond to the head, the four limbs and the tail of the laboratory mouse one to one are further arranged on the base. The utility model provides a heart perfusion device, be applicable to heart and blood vessel infusion liquid to the laboratory mouse, wash the blood vessel, so that last section detects, hang an infusion bottle respectively on every couple at infusion bottle peg both ends, respectively put a liquid in every infusion bottle, be PBS solution (normal saline) and stationary liquid (4% paraformaldehyde) respectively, use PBS to wash away after the pipeline earlier, the syringe needle inserts laboratory mouse apex of the heart position, it is fixed with hemostatic forceps, defeated PBS solution, cut open right auricle simultaneously, put the mouse blood, change paraformaldehyde and fill after effluent becomes colorless transparent (perfusion volume is about 80mL), perfusion speed is adjustable, can realize fast and slow speed conversion and at the heart perfusion speed of uniform velocity, can monitor and fill and go on, avoid importing the air to the laboratory mouse in vivo, protect each organ of laboratory mouse, tissue etc. do not receive the harm, the infusion height-adjustable, set up intellectual detection system module, can with customer end and host computer both-way communication, realize human-computer interaction, still can weigh the laboratory mouse weight, and show at display module, can realize intelligent illumination and warning, monitoring box and storage box are detachable installs on the base, can dismantle according to the actual demand, carry out light, electric energy conversion through solar cell panel, energy saving and consumption reduction, low cost, simple structure, stability is high, the function is diversified, the practicality is strong, more is fit for using widely.

Drawings

Fig. 1 is a schematic structural view of the present invention;

fig. 2 is a schematic structural view of the adhesive strip of the present invention;

fig. 3 is a schematic structural view of a solar cell panel of the present invention;

fig. 4 is a schematic structural view of the lifting adjusting rope and the fixing rod of the present invention;

wherein, 1, the transfusion bracket body; 2-1, a base; 2-2, a transfusion column; 3-fixing the through hole; 4. hooking; 5. an infusion bottle; 6. a flexible infusion tube; 7. a flow rate regulator; 8. a needle head; 9. a lift adjustment cord; 10. a drip cup; 11. a hanging rod of the infusion bottle; 12. fixing the rod; 13. a monitoring box; 14. a bonding strip; 15. a storage box; 16. an LED lamp; 17-a solar panel; and 18-a drainage diversion groove.

Detailed Description

Embodiments of the present invention will be described in detail below with reference to the accompanying drawings, so that the advantages and features of the invention can be more easily understood by those skilled in the art, thereby making the scope of the invention more clearly defined.

As shown in figures 1-4, a heart perfusion device comprises a transfusion bracket body 1, the transfusion bracket body 1 comprises a base 2-1 and a vertically placed transfusion column 2-2, the base 2-1 and the transfusion column 2-2 are mutually vertically placed, the top of the transfusion column 2-2 is provided with a transfusion bottle hanging rod 11 with two ends respectively provided with a hook 4, each hook 4 is respectively hung with a plurality of transfusion bags 5, the number of the transfusion bags 5 is not limited, the transfusion column 2-2 is longitudinally provided with a plurality of fixing through holes 3 for adjusting the height of the transfusion bag 5, in order to improve the height adjusting precision, a graduated scale is vertically arranged on the transfusion column 2-2, an operator can adjust the height according to a graduation line, the top of the transfusion bag 5 is connected with a lifting adjusting rope 9 and extends into the fixing through holes 3 at different positions through a fixing rod 12 arranged on the lifting adjusting rope 9 to realize height adjustment, the fixing through holes 3 are designed into through holes, an operator can adjust the height in the front and back directions, the fixing rods 12 are directly tied with the lifting adjusting ropes 9, the fixing rods 12 only need to be inserted into the fixing through holes 3 at different positions, the fixing rods are convenient and simple, a part of the fixing rods 12 extends out of two ends after being inserted, the fixing rods 12 are prevented from falling off from the fixing through holes 3 due to too short length, the stability of the device is improved, each infusion bag 5 is respectively communicated with an infusion hose 6 with a needle 8 and a drip cup 10, the needle 8 is inserted into the heart of an experimental mouse by adopting the prior art, the infusion body is infused into the experimental mouse through the infusion hose 6, a flow rate regulator 7 for regulating the flow rate is arranged on the infusion hose 6, the existing structure is adopted, a monitoring box 13 provided with an intelligent detection module is detachably arranged on the base 2-1, and the intelligent detection module comprises a main control, The experimental mouse comprises a weighing module, an illuminating module, an alarming module, a display module, a wireless communication module and a power supply module, wherein the input end of a main control module is connected with the weighing module, the output end of the main control module is connected with the illuminating module, the alarming module and the display module, the main control module is connected with a client and an upper computer through the wireless communication module to carry out two-way communication, the main control module can receive instructions transmitted by the client or the upper computer and control corresponding electric modules to respond according to the instructions, a plurality of sticking strips 14 which are in one-to-one correspondence with the head, the neck and the four limbs of the experimental mouse are further arranged on a base 2-1, when the experimental mouse is placed on the base 2-1, the head of the experimental mouse is fixed through the sticking strips 14 which are in correspondence with the head and the neck, the four limbs of the experimental mouse are fixed through the sticking strips 14 which are in correspondence, Simple and low in cost.

The storage box 15 is detachably mounted on the base 2-1 through bolts, the storage box 15 can be conveniently and quickly taken down from the base 2-1, the front and back of the storage box 15 are opened, the storage box 15 is made of transparent plastic, a plurality of hollowed-out holes are formed in the left side wall and the right side wall of the storage box 15 and can be pentagonal or other patterns, the hollowed-out holes can be selected by a user according to the user demand, the storage box is elegant and attractive, the practicability is high, an operator can place experimental supplies in the storage box 15, the transparency is good, the operator can conveniently and quickly find out products to be used, and the working efficiency is improved.

The monitoring box 13 is detachably arranged on the base 2-1 through bolts, so that the monitoring box 13 can be conveniently and quickly taken down from the base 2-1, the monitoring box 13 is of a hollow structure and is elegant and attractive, the illuminating module is an LED lamp 16 and is placed at the top of the monitoring box 13, the LED lamp 16 is connected with the output end of the main control module and is controlled to be opened and closed through the main control module, an intelligent detection module is arranged in the monitoring box 13, the main control module is a single chip microcomputer or PLC and is internally provided with a storage module, a weight threshold value is preset in the storage module and is called by the main control module, the weighing module is an electronic scale, the alarm module is a buzzer, the display module is an LED liquid crystal display screen, the wireless communication module is a 4G, 5G, Wi-Fi, Bluetooth or Zigbee module, the power supply module is a solar panel 17, the solar panel 17 is designed to be wavy, the light, the solar cell panel 17 converts light energy into electric energy and saves the electric energy in the electric energy storage module matched with the solar cell panel, the electric energy storage module supplies power for the main control module, the weighing module, the lighting module, the alarm module, the display module and the wireless communication module, and the included angle between the plane of the solar cell panel 17 facing the sun and the vertical direction is 30-45 degrees, so that the light energy utilization rate is further improved. The utility model discloses still set up a plurality of sections lithium ion battery on monitoring box 13, as reserve power module, be connected and supply power for each module with host system, weighing module, lighting module, alarm module, display module, wireless communication module.

The base 2-1 is horizontally placed, a layer of rubber pad is laid on the base 2-1, the thickness of the rubber pad is 1-5mm, and the rubber pad is soft and good in touch feeling.

The U-shaped drainage diversion groove 18 is formed in the base 2-1, one end or two ends of the drainage diversion groove 18 are respectively communicated with a waste liquid bottle used for storing waste liquid, the waste liquid flows into the external waste liquid bottle through the drainage diversion groove 18, the specific position of the drainage diversion groove 18 can be selected according to actual requirements, the purpose of liquid drainage can be achieved only by ensuring the drainage diversion groove, the waste liquid is ensured not to flow disorderly in the experimental process, and the environment is kept clean and tidy.

The utility model discloses a theory of operation does:

after the device is installed, an operator can selectively place the experimental mouse in a weighing module area for weighing according to actual requirements, and then upload the weight of the experimental mouse to a main control module, the weight of the experimental mouse is displayed through a display module, the weight of the experimental mouse is uploaded to a client and an upper computer through a wireless communication module for protection and backup, later-period checking is facilitated, meanwhile, the main control module also compares actual weight data uploaded by the weighing module with a preset weight threshold value, if the actual weight data exceeds the preset weight threshold value or is lower than the preset weight threshold value, the main control module drives an alarm module to give an alarm, and meanwhile, the actual weight data is uploaded to the client and the upper computer for protection and backup, if the power supply module is too low, a monitoring box 13 can be quickly taken down from a base 2-1 and placed outdoors with sufficient light for photoelectric conversion, or a new lithium ion battery is used; hang an infusion bag 5 on every couple 4 respectively, respectively put a liquid in two infusion bags 5, do respectively: PBS solution (normal saline) and stationary liquid (4% paraformaldehyde), inject the syringe needle 8 into the apex of heart of the white rat, fix with hemostatic forceps, transfusion PBS solution, cut off the right auricle at the same time, after the effluent becomes colorless transparent (the perfusion volume is about 80mL), change paraformaldehyde and pour into, blood can realize circulating through the systemic circulation, in the infusion process, can regulate the flow rate through the flow rate regulator 7, realize high-low speed change and at the uniform infusion, protect the laboratory rat viscera from not being damaged, waste blood, buffer solution and stationary liquid are discharged in the waste liquid bottle through the drainage water conservancy diversion recess 18 on the base 2-1 in the experiment.

The utility model discloses the part of not detailed description adopts to present can realize, does not describe here any more.

The above only is the embodiment of the present invention, not limiting the patent scope of the present invention, all the equivalent structures or equivalent processes that are used in the specification and the attached drawings or directly or indirectly applied to other related technical fields are included in the patent protection scope of the present invention.

Claims (8)

1. A heart perfusion device is characterized by comprising a transfusion support body (1), wherein the transfusion support body (1) comprises a base (2-1) and a vertically-arranged transfusion column (2-2), the base (2-1) and the transfusion column (2-2) are mutually and vertically arranged, the top of the transfusion column (2-2) is provided with a transfusion bottle hanging rod (11) with hooks (4) at two ends, a transfusion bag (5) is hung on the hooks (4), the transfusion column (2-2) is longitudinally provided with a plurality of fixing through holes (3) for adjusting the height of the transfusion bag (5), the top of the transfusion bag (5) is connected with a lifting adjusting rope (9) and extends into the fixing through holes (3) at different positions to realize height adjustment through a fixing rod (12) arranged on the lifting adjusting rope (9), the transfusion bag (5) is communicated with a transfusion hose (6) with a needle (8) and a drip cup (10), set up flow rate regulator (7) on infusion hose (6), detachable place monitoring box (13) that are equipped with intelligent detection module on base (2-1), intelligent detection module includes host system, weighing module, lighting module, alarm module, a display module, wireless communication module and power module, host system and weighing module, lighting module, alarm module, display module and power module are connected, host system passes through wireless communication module and customer end and host computer connection, carry out two-way communication, still set up a plurality of on base (2-1) respectively with the sticking strip (14) of experimental mouse's neck portion and four limbs one-to-one.

2. A cardiac perfusion apparatus as defined in claim 1, wherein the base (2-1) is detachably mounted with a storage case (15) by bolts, the storage case (15) being open at the front and rear.

3. A cardiac perfusion apparatus as defined in claim 2, wherein the reservoir (15) is made of transparent plastic, and a plurality of holes are formed in the left and right side walls of the reservoir (15).

4. A heart perfusion device according to claim 1, wherein the monitoring box (13) is detachably mounted on the base (2-1) by bolts, the monitoring box (13) is a hollow structure, and the illumination module is an LED lamp (16) and is placed on the top of the monitoring box (13).

5. The heart perfusion device of claim 1, wherein the main control module is a single chip microcomputer or a PLC, the weighing module is an electronic scale, the alarm module is a buzzer, the display module is an LED liquid crystal display, the wireless communication module is a 4G, 5G, Wi-Fi, Bluetooth or Zigbee module, and the power supply module is a solar panel (17).

6. A cardiac perfusion device according to claim 1, wherein a rubber pad is applied to the base (2-1).

7. A cardiac perfusion device according to claim 6, wherein the rubber pad is 1-5mm thick.

8. A cardiac perfusion device according to claim 1, wherein the base (2-1) is provided with drainage guide grooves.

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