CN212722627U - Test paper strip color development detection device - Google Patents
Test paper strip color development detection device Download PDFInfo
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- CN212722627U CN212722627U CN202021708457.5U CN202021708457U CN212722627U CN 212722627 U CN212722627 U CN 212722627U CN 202021708457 U CN202021708457 U CN 202021708457U CN 212722627 U CN212722627 U CN 212722627U
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Abstract
The utility model discloses a test paper strip color development detection device, test paper strip color development detection device is used for detecting test paper strip color reaction's colour, including optical emission module and light receiving module, optical emission module includes the light source, the light source is used for setting up to transmission incident light to test paper strip, the incident light is used for forming the reverberation through the test paper strip reflection, light receiving module set up in receive with the realization on the reflection path of reverberation the reverberation. The test strip color development detection device has the advantages that the detection effect is good and the accuracy is high by improving the set path and optimizing the detection mode of the photoelectric colorimetric method; and the traditional visual inspection method is replaced by an automatic or semi-automatic detection means, so that the accuracy and the detection efficiency are high.
Description
Technical Field
The utility model relates to a photoelectric detection instrument technical field, in particular to test paper strip colour development detection device.
Background
The immune colloidal gold method is a commonly used instant detection mode and is widely applied to the fields of biochemical reagent inspection, animal and plant immune tests, medical in-vitro diagnosis and the like.
In the immune colloidal gold method, a solution containing an object to be detected is subjected to a capillary action of a chromatography test strip, and undergoes color development reaction with colloidal gold particles in a detection line (T line) and a quality control line (C line) area respectively along the test strip. The traditional detection method is a visual detection method, and the development is generally towards an automatic or semi-automatic detection instrument at present in consideration of visual differences of detection personnel and the condition that a large number of samples need to be processed.
Therefore, it is an urgent need to solve the technical problem of the art to provide a test strip color development detection device that uses an automatic or semi-automatic detection means to replace the conventional visual detection method.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a test strip color development detection device, which not only has good detection effect and high accuracy by improving the setting path and optimizing the detection mode of a photoelectric colorimetric method; and the traditional visual inspection method is replaced by an automatic or semi-automatic detection means, so that the accuracy and the detection efficiency are high.
In order to achieve the above object, the utility model provides a test paper strip colour development detection device, test paper strip colour development detection device is used for detecting test paper strip colour reaction's colour, including optical emission module and light receiving module, optical emission module includes the light source, the light source is used for setting up to transmission incident light to test paper strip, the incident light is used for forming the reverberation through the test paper strip reflection, light receiving module set up in order to realize receiving on the reflection path of reverberation the reverberation the reverberation.
Preferably, the light source is configured to emit the incident light to the test strip to form an emission path, and a condensing lens configured to condense light of the incident light is disposed on the emission path.
Preferably, the condenser lens includes an aspherical lens and a plano-convex lens, and the aspherical lens is disposed upstream of the emission path with respect to the plano-convex lens.
Preferably, the light source is provided as a light emitting diode or a laser diode.
Preferably, the color of the light source is complementary to the color of the test strip for color reaction.
Preferably, the color of the light source is set to green when the color of the color reaction of the test strip is set to red.
Preferably, the light source is provided in plurality, and a plurality of the light sources are provided to emit the incident light of a plurality of colors.
Preferably, the light emitting module and the light receiving module are disposed on the mounting base, and the light emitting module and the light receiving module are disposed symmetrically with respect to the normal of the incident light and the reflected light.
Preferably, the light receiving module includes a photoelectric conversion unit, a signal amplification unit, and a result analysis unit, the photoelectric conversion unit is configured to convert the received reflected light into an electrical signal, the signal amplification unit is configured to amplify the converted electrical signal into an amplified electrical signal, and the result analysis unit is configured to analyze the amplified electrical signal to obtain a result.
Preferably, the reflecting path is further provided with a diaphragm, and the diaphragm is located upstream of the reflecting path relative to the light receiving module.
Compared with the prior art, the utility model provides a test paper strip color development detection device, test paper strip color development detection device are used for detecting the colour of test paper strip color reaction, and it includes light emitting module and light receiving module, and light emitting module includes the light source, and the light source sets up to launching incident light to the test paper strip, and the incident light forms the reverberation through the test paper strip reflection, and light receiving module sets up on the reflection path of reverberation; the test strip color development detection device realizes that a light source beam serving as incident light is emitted towards a test strip through the light emitting module, collects the residual reflected light of the light source beam after being absorbed by the test strip through the light receiving module and analyzes the residual reflected light to obtain the detection result of the test strip, the light receiving module on the reflection path can receive the reflected light with the strongest light or the largest energy after being emitted by the light emitting module, and the detection method of the photoelectric colorimetry is optimized to improve the detection effect and the accuracy by improving the set path to remove redundant parasitic light; this test paper strip colour development detection device replaces traditional range estimation method with automatic or semi-automatic detection means, and not only it is high to detect sensitive degree of accuracy, and detection speed is fast moreover, and it is faster to carry out the analysis than the photo on the detection speed of single test paper strip, can also detect many test paper strips simultaneously in the mode of the combination of array arrangement, and detection efficiency is high.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a test strip color development detection device provided by an embodiment of the present invention;
FIG. 2 is a schematic diagram of the relationship of the light receiving module in FIG. 1;
fig. 3 is an installation schematic diagram of the test paper strip color development detection device provided by the embodiment of the utility model.
Wherein:
the device comprises a light source 1, a aspheric lens 2, a plano-convex lens 3, a colloidal gold test strip 4, a stray light diaphragm 5, a photoelectric detector 6, a result analysis unit 7, a mounting seat 8, a photoelectric conversion unit 61 and a signal amplification unit 62.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In order to make the technical field of the present invention better understand, the present invention will be described in detail with reference to the accompanying drawings and the detailed description.
Please refer to fig. 1 to fig. 3, wherein fig. 1 is a schematic structural diagram of a test paper strip color development detection device provided by an embodiment of the present invention, fig. 2 is a schematic relationship diagram of a light receiving module in fig. 1, and fig. 3 is an installation diagram of the test paper strip color development detection device provided by an embodiment of the present invention.
In a specific implementation manner, the utility model provides a test paper strip color development detection device is used for detecting test paper strip color reaction's colour, and it includes light emitting module and light receiving module, and light emitting module includes light source 1, and light source 1 emits the light beam formation transmission light to the test paper strip, and the incident light forms the reverberation through the test paper strip reflection, and light receiving module sets up on the reflection path of reverberation, receives the reverberation by light receiving module.
Particularly, the test paper strip specifically is colloidal gold test paper strip 4, in test paper strip colour development detection device's use, keep flat colloidal gold test paper strip 4 in the desktop, the mounting of light emitting module and light receiving module accessible support isotructure is fixed in the desktop, also can artifical handheld fixed, the mounted position and the angle of light emitting module and light receiving module should change as required, that is to say, the mounted position of light emitting module and light receiving module relative colloidal gold test paper strip 4 and the angle between colloidal gold test paper strip 4 can change according to the experiment needs.
Further, the light source 1 emits incident light to the test strip to form an emission path, and a condensing lens is arranged on the emission path and used for condensing the incident light. That is to say, the condensing lens is arranged between the light source 1 and the colloidal gold test strip 4, and the light beam of the light source can be shaped by adopting the optical lens to meet the detection requirement, so that the width of the light spot of the detection light falling on the test strip is not more than that of the CT line, and the detection accuracy is improved.
The light source 1 is a light emitting diode or a laser diode with a divergence angle, and on this basis, the light source 1 may also be a similar light source based on this, and should also belong to the description scope of the present embodiment.
In addition, the lens can be arranged in a manner of combining a plurality of groups of lenses, including the combined arrangement of the lenses without limitation on the number and the spherical surface and the aspheric surface; illustratively, the optical lens system comprises at least one aspheric lens 2 and at least one plano-convex lens 3, and the aspheric lens 2 is arranged at the upstream of the emission path relative to the plano-convex lens 3. That is to say, aspheric lens 2 is close to light source 1 and sets up, and plano-convex lens 3 keeps away from light source 1 and sets up for the light source light beam passes through aspheric lens 2 and plano-convex lens 3 and focuses on colloidal gold test paper strip 4, but manually move colloidal gold test paper strip 4 or if place colloidal gold test paper strip 4 on moving platform through moving mechanism, thereby make colloidal gold test paper strip 4 and the focus point of light source light beam produce relative motion, the direction of motion is perpendicular with CT line direction.
Illustratively, the light emitting module and the light receiving module are symmetrically arranged with respect to a normal of the incident light and the reflected light. That is to say, the light emitting module and the light receiving module are symmetrically arranged and respectively located on the incident path and the reflection path, so that after the light source light beam emitted by the light emitting module along the incident path is reflected by the colloidal gold test strip 4, the reflected light can be received by the light receiving module under the condition of the strongest light or the largest energy. Compared with installation paths at other angles, the method and the device have the advantages that the optimal path is set, redundant stray light is removed, and the detection mode of the photoelectric colorimetry is optimized, so that the detection effect and accuracy are improved.
On the basis, a bracket for fixing the components, such as a mounting seat 8 and the like, can be additionally arranged, so that the light emitting module and the light receiving module are fixedly mounted and can be completely fixed on the optimal path, and the angle can be adjusted to achieve the adjustment to the optimal path.
In this embodiment, the colloidal gold test strip 4 is used to make the colloidal gold particles in the CT line region and the solution generate a color reaction by using the CT line, i.e., the T line of the inspection line and the C line of the quality control line, and then obtain a detection result of the color reaction by using the light emitting module and the light receiving module, and replace the conventional visual inspection method with this process.
Specifically, the light emitting module is used for emitting a light source beam to the colloidal gold test strip 4, the light source beam is divided into reflected light, absorbed light and scattered light in a CT line region of the colloidal gold test strip 4, and the light receiving module is used for collecting the reflected light and analyzing the reflected light to obtain a detection result, in a simple manner, a result of whether a color reaction occurs in the CT line region is obtained.
In the use, fixed optical transmission module and light receiving module of installation, leave the slope contained angle between optical transmission module and the colloidal gold test paper strip 4 for optical transmission module can be gathered by light receiving module after reflecting to the light source light beam of colloidal gold test paper strip 4 transmission, and the distance between optical transmission module and the optical receiving module, with the distance between colloidal gold test paper strip 4 and with the contained angle between colloidal gold test paper strip 4 can change according to the experiment needs, do not specifically limit here. On the basis, the light receiving module can analyze and judge whether the CT line area of the colloidal gold test strip 4 has a color reaction result according to the collected reflection signal.
In one embodiment, the color of the light source beam is complementary to the color of the colloidal gold test strip 4, i.e. the light source beam emitted by the light emitting module or the light source 1 is complementary to the color of the colloidal gold test strip 4.
Specifically, when the colloidal gold test strip 4 develops color, the emitted light of complementary color, that is, the light source beam, is completely absorbed at the colloidal gold test strip 4, so there is no reflected light, and the light receiving module cannot detect the reflected light, and when the light receiving module detects no reflected light, it is determined that the colloidal gold test strip 4 develops color; similarly, when the colloidal gold test strip 4 does not develop color, the light beam of the light source is not absorbed at the colloidal gold test strip 4, and thus is reflected completely, and when the reflected light exists, the light receiving module detects the reflected light, and when the reflected light exists, the light receiving module determines that the colloidal gold test strip 4 does not develop color.
On this basis, the present embodiment does not limit the light source beam to be only a specific color, as long as the light source beam and the color developed by the colloidal gold test strip 4 form a complementary color, that is, the light source beam with different colors can be selected according to different colloidal gold test strips 4, and the present embodiment also belongs to the scope of the present embodiment. Illustratively, when the color of the colloidal gold test strip 4 is red, the color of the light beam of the light source is green; when the color development of the colloidal gold test strip 4 is orange, the color of the light beam of the light source is blue; when the color development of the colloidal gold test strip 4 is purple, the color of the light beam of the light source is yellow.
In this embodiment, the light source 1 is switchable, the light sources 1 may be provided in plural, the plural light sources 1 may correspond to the switchable incident light with plural colors, and the specific number and color may be adjusted according to the scheme of the colloidal gold test strip 4; the CT line is detected by adopting a complementary color light source for color development reaction by a colloidal gold method, the judgment basis of the light receiving module is reflected light or no reflected light, and the judgment of the existence of the reflected light is more accurate, so that the device has high sensitivity, high accuracy of weak positive judgment, high detection speed and high detection efficiency.
In the detection principle of the test strip color development detection device, detection light emitted by the light emitting module irradiates on the colloidal gold test strip 4, and the detection light and the test strip surface can be divided into three parts after interaction, namely reflected light, absorbed light and scattered light, and the intensities of the reflected light, the absorbed light and the scattered light are I in sequencer、IaAnd IsThe intensity of the detected light is I0And satisfies the following conditions: i is0-Ia＝Ir+Is(ii) a Considering the smoothness of the chromatographic surface of the gold-labeled card test paper, the surface of the gold-labeled card test paper is mainly absorbed and reflected by light, and scattered light is ignored, so that I0-Ia＝Ir(ii) a The test strip color development detection device in this embodiment can be regarded as a reflective lambert-beer model.
In the selection of the light source beam of the light emitting module, that is, the detection light, a certain color light with higher CT line absorbance is obtained through experimental tests or data query, and the light source 1 of the color system is selected.
In the present embodiment, the light receiving module includes a photoelectric conversion unit 61, a signal amplification unit 62, and a result analysis unit 7, the photoelectric conversion unit 61 converts the received reflected light into an electrical signal, the signal amplification unit 62 amplifies the converted electrical signal into an amplified electrical signal, and the result analysis unit 7 analyzes the amplified electrical signal to obtain a result.
More specifically, the light receiving module includes a photodetector 6, the photodetector 6 such as a photocell can be used to collect the reflected signal of the test paper surface, and then the reflected light intensity of the CT line is analyzed and compared to obtain the detection result, the photodetector 6 has a photoelectric conversion unit 61 and a signal amplification unit 62 connected, the signal amplification unit 62 is further connected to the result analysis unit 7, the photoelectric conversion unit 61 is used to convert the optical signal into an electrical signal, and the signal amplification unit 62 performs operational amplification on the electrical signal obtained in the previous step.
More specifically, the result analysis unit 7 may be further configured as a result analysis and display unit, including the result analysis unit 7 and the display unit, and the signal intensities at the C line and the T line are calculated as I respectively, with the intensity of the reflected light signal at the blank of the test strip calibrated by the white block being 100%CAnd ITIn ICIf the value is less than the critical value a, the judgment I is carried outTGiving out and displaying a positive and negative judgment result at the position of the result-intensity interval table; if ICIf the value is higher than the critical value a, the test paper is failed or the detection is failed. The critical value a and the result-intensity interval table are obtained by statistics of relevant experimental data and are influenced by factors such as the incident angle of detection light, the surface smoothness of the test paper, the size of the stray light diaphragm 5 and the like.
Further, a diaphragm is arranged on the reflection path, and the diaphragm is located at the upstream of the reflection path relative to the light receiving module.
More specifically, the diaphragm is specifically a stray light diaphragm 5, the stray light diaphragm 5 is arranged between the photoelectric detector 6 and the colloidal gold test strip 4, and the stray light diaphragm 5 is used for blocking scattered light and a small amount of reflected light outside a CT line, so that the reliability of the Lambor-beer model is ensured.
Illustratively, the diameter of the stray light diaphragm 5 should not be larger than the minimum width of the CT line of the colloidal gold test strip 4 to reduce the interference of the background light, and the photodetectors 6 are used to collect the light absorption rates at the C line and the T line respectively for determining the reliability and the detection result of the test strip.
In a specific embodiment, when using, can establish test paper strip colour development detection device's quantity into the multiunit, multiunit test paper strip colour development detection device array arranges and makes up, and this test paper strip colour development detection device relates to the device small in quantity and little, and whole volume can be done less, can adopt a plurality of arrays of carrying on arrange and make up, realizes once many detection methods, promotes detection efficiency.
In this embodiment, this test paper strip colour development detection device's single setting has solved the problem that traditional range estimation method exists, in addition, current shoot and obtain detection result's detection device after image processing, the image acquisition module is bulky, with high costs, image algorithm analysis precision is low, and image quality is easily influenced by the illumination condition, false negative sample detects more, and image collector (CCD or CMOS) supporting analysis hardware resource occupancy is high, is unfavorable for improving detection speed, and the utility model relates to a device is small and small in quantity, and whole volume can be done less, and is with low costs, also can be faster than taking the picture to analyze in the detection rate of single test paper strip.
On the basis, the external structural part of the device changes along with the parameters and the layout of elements in the optical path, and has small integral volume and light weight, thereby being convenient for array integration; and then this test paper strip colour development detection device can adopt a plurality of arrays of carrying on arrange and make up, realizes the detection mode of once many, promotes detection efficiency, has solved most check out test set and can only once detect a reaction test paper, can not satisfy the problem of the detection demand of a large amount of samples.
It is noted that, in this specification, relational terms such as first and second, and the like are used solely to distinguish one entity from another entity without necessarily requiring or implying any actual such relationship or order between such entities.
It is right above the utility model provides a test paper strip colour development detection device has carried out detailed introduction. The principles and embodiments of the present invention have been explained herein using specific examples, and the above descriptions of the embodiments are only used to help understand the method and its core ideas of the present invention. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, the present invention can be further modified and modified, and such modifications and modifications also fall within the protection scope of the appended claims.
Claims (10)
1. The utility model provides a test paper strip color development detection device, test paper strip color development detection device is used for detecting the colour of test paper strip color reaction, its characterized in that includes light emitting module and light receiving module, light emitting module includes light source (1), light source (1) are used for setting up to launching incident light to the test paper strip, incident light is used for forming the reverberation through the test paper strip reflection, light receiving module set up in on the reflection path of reverberation in order to realize receiving the reverberation.
2. The test strip color development detection device of claim 1, wherein the light source (1) is configured to emit the incident light to the test strip to form an emission path, and a condensing lens configured to condense light of the incident light is disposed on the emission path.
3. The test strip color development detection device of claim 2, wherein the condenser lens comprises an aspheric lens (2) and a plano-convex lens (3), and the aspheric lens (2) is disposed upstream of the emission path relative to the plano-convex lens (3).
4. The test strip color development detection device of claim 1, wherein the light source (1) is configured as a light emitting diode or a laser diode.
5. The test strip color development detection device of any one of claims 1 to 4, wherein the color of the light source (1) is configured to be complementary to the color of the test strip color development reaction.
6. The test strip color development detection device of claim 5, characterized in that the color of the light source (1) is set to green when the color of the test strip color development reaction is set to red.
7. The test strip color development detection device of claim 5, wherein the light source (1) is provided in plurality, and the plurality of light sources (1) are provided to emit the incident light of a plurality of colors.
8. The test strip color development detection device of claim 5, wherein the light emitting module and the light receiving module are disposed on a mounting seat (8), and the light emitting module and the light receiving module are disposed symmetrically with respect to the normal of the incident light and the reflected light.
9. The test strip color development detection device of claim 5, wherein the light receiving module comprises a photoelectric conversion unit (61), a signal amplification unit (62), and a result analysis unit (7), the photoelectric conversion unit (61) is configured to convert the received reflected light into an electrical signal, the signal amplification unit (62) is configured to amplify the converted electrical signal into an amplified electrical signal, and the result analysis unit (7) is configured to analyze the amplified electrical signal to obtain a result.
10. The device for detecting color development of test strip of claim 9, wherein the reflective path further comprises a diaphragm, and the diaphragm is located upstream of the reflective path relative to the light receiving module.
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| CN202021708457.5U CN212722627U (en) | 2020-08-14 | 2020-08-14 | Test paper strip color development detection device |
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| CN202021708457.5U CN212722627U (en) | 2020-08-14 | 2020-08-14 | Test paper strip color development detection device |
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| CN212722627U true CN212722627U (en) | 2021-03-16 |
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