CN212630766U - Medical detection equipment and measurement component thereof - Google Patents

Abstract

The application relates to a medical check out test set and medical check out test set's measurement element, medical check out test set includes: a housing; and the measuring component is arranged on the outer wall of the shell and used for measuring the concentration of the parameter to be measured in the external environment of the shell. Therefore, the medical detection device in the embodiment of the application can realize the detection of various parameters (including the pH value, the occult blood concentration, the pepsin concentration, the trypsin concentration and the like) in the digestive tract by arranging the measuring component, thereby improving the accuracy of the detection result of the medical detection device on the digestive tract, enabling the medical detection device to have multiple functions and improving the practicability of the medical detection device.

Description

Medical detection equipment and measurement component thereof

Technical Field

The application relates to the technical field of medical instruments, in particular to a medical detection device and a measurement component of the medical detection device.

Background

With the acceleration of life rhythm, the life pressure of people is gradually increased, and digestive tract diseases become disease types which seriously affect the life quality of people due to the change of dietary structure. The diagnosis and treatment of digestive tract diseases are based on the accurate examination of physiological parameters and mucosal state of the digestive tract.

At present, an endoscope device is usually adopted to visually observe the alimentary canal mucosa, but due to the limitation of technical integration, the endoscope on the market can only observe the images of the alimentary canal mucosa, but cannot acquire other useful information in the alimentary canal. Therefore, the existing endoscope device has single function and cannot finish accurate detection of the digestive tract.

SUMMERY OF THE UTILITY MODEL

The application provides a medical detection device and a measurement component thereof, and the detection accuracy of the medical detection device is higher.

A first aspect of an embodiment of the present application provides a medical detection apparatus, including:

a housing;

and the measuring component is arranged on the outer wall of the shell and used for measuring the concentration of the parameter to be measured in the external environment of the shell.

In one possible design, the measurement component includes a polyion gel and a dye, the dye being filled in the polyion gel;

the dye can change color when the concentration of the parameter to be measured is different.

In one possible design, the measurement component includes one or more of a pH measurement component, a occult blood measurement component, a pepsin measurement component, a trypsin measurement component.

In one possible design, the dye of the pH measurement component is a pH sensitive dye that is capable of changing color in environments with different pH values.

In one possible design, hydrogen ions in the environment outside the housing can enter the pH measurement component through the polyion gel, and hydrogen ions in the pH measurement component can enter the environment outside the housing through the polyion gel;

the pH sensitive dye can bind to or separate from hydrogen ions to form a dynamic equilibrium.

In one possible design, the dye of the occult blood measurement component comprises a methylene blue dye that is capable of changing color in environments with different occult blood concentrations.

In one possible design, hemoglobin in the environment external to the housing is capable of binding and reacting with the polyionic gel and the methylene blue dye in the occult blood measurement component;

under the effect of hemoglobin, through redox reaction, the methylene blue dye can show the colour, and the concentration of hemoglobin is different, the colour that the methylene blue dye shows is different.

In one possible design, the dye of the pepsin measurement part comprises a bromophenol blue dye, which is capable of changing color in environments with different pepsin concentrations.

In one possible design, pepsin in the environment external to the housing is capable of binding to the polyion gel and the bromophenol blue dye in the pepsin measurement component;

the light scattering signals of the bound bromophenol blue dye change to show different colors, and the colors of the bromophenol blue dye are different when the concentration of pepsin is different.

In one possible design, the dye of the trypsin measuring part comprises a bromocresol purple dye, which is capable of changing color in environments with different trypsin concentrations.

In one possible design, trypsin in the environment external to the housing is capable of binding to polyionic gel and bromocresol purple dye in the trypsin measurement component;

the volume of the combined bromocresol purple dye is changed, the light scattering signal is changed, different colors are shown, and the colors of the bromocresol purple dye are different when the concentration of trypsin is different. In one possible embodiment, the arrangement of the measuring elements on the outer wall of the housing is a segmented arrangement or an alternating arrangement.

In one possible design, the medical testing device includes a plurality of the measurement members;

the ranges of the measurement components are not exactly the same, and/or the resolutions of the measurement components are not exactly the same.

In one possible design, the housing comprises a transparent portion;

the medical detection equipment further comprises an image component, wherein the image component is located in the inner cavity of the shell, and the image component can observe the environment outside the shell through the transparent part.

In one possible design, the housing includes first and second opposite end portions in an axial direction, each of the first and second end portions including the transparent portion;

the medical detection equipment comprises two image parts, wherein the two image parts are respectively arranged corresponding to the two transparent parts;

the measuring part is mounted on the outer wall of the first end part or the second end part; alternatively, the first and second electrodes may be,

the medical detection device at least comprises a first measurement component and a second measurement component, the range of the first measurement component is different from that of the second measurement component, one of the first measurement component and the second measurement component is arranged on the outer wall of the first end part, and the other one of the first measurement component and the second measurement component is arranged on the outer wall of the second end part.

In one possible design, the medical testing device further includes a data transmission assembly;

the image component comprises a lens and an image sensor, and the lens is connected with the image sensor through a mechanical structure and/or glue;

the image sensor is electrically connected or in signal connection with the data transmission assembly, and the lens is connected with the data transmission assembly through a mechanical structure and/or glue.

In one possible design, the lens is mounted in the inner cavity of the shell, and the lens has an effective imaging angle α 1, and the transparent part can cover the space where the effective imaging angle α 1 is located;

the image sensor is provided with a display image angle alpha 2, the transparent part can cover the space where the display image angle alpha 2 is located, and alpha 1 is larger than alpha 2;

the measuring component is arranged on the outer wall of the shell and is positioned in a space between the effective imaging angle alpha 1 and the display image angle alpha 2;

the data transmission assembly is capable of reading data of the measurement component.

In one possible design, the lens is mounted in the inner cavity of the shell, and the lens has an effective imaging angle α 1, and the transparent part can cover the space where the effective imaging angle α 1 is located;

the image sensor is provided with a display image angle alpha 2, the transparent part can cover the space where the display image angle alpha 2 is located, and alpha 1 is larger than alpha 2;

the measuring component is arranged on the outer wall of the shell and is positioned in a space occupied by the display image angle alpha 2;

the image sensor is capable of identifying data of the measurement component.

In one possible design, the measurement component is located in the middle of the space occupied by the display image angle α 2.

In one possible embodiment, the measuring element is glued to the outer wall of the housing by means of a transparent glue.

In one possible design, the measuring component is further adhered to the outer wall of the housing through an edge sealing adhesive, and the edge sealing adhesive covers the outer edge of the measuring component.

In one possible design, the shell is a capsule-type structure;

the medical detection equipment is a capsule endoscope.

A second aspect of the embodiments of the present application provides a measurement component of a medical detection apparatus, where the measurement component includes a polyion gel and a dye, and the dye is filled in the polyion gel;

the dye can change color when the concentration of the parameter to be measured is different.

Therefore, the medical detection device in the embodiment of the application can realize the detection of various parameters (including the pH value, the occult blood concentration, the pepsin concentration, the trypsin concentration and the like) in the digestive tract by arranging the measuring component, thereby improving the accuracy of the detection result of the medical detection device on the digestive tract, enabling the medical detection device to have multiple functions and improving the practicability of the medical detection device.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

FIG. 1 is a schematic diagram of a medical testing device according to a first embodiment of the present disclosure;

FIG. 2 is an exploded view of FIG. 1;

FIG. 3 is a partial cross-sectional view of FIG. 1;

FIG. 4 is a schematic structural view of the measurement unit of FIG. 1;

FIG. 5 is a schematic view of the measurement component of FIG. 4 coupled to a housing;

FIG. 6 is a schematic diagram of a second embodiment of a medical testing device provided herein;

FIG. 7 is a schematic structural view of a medical testing device provided in the present application in a third embodiment;

FIG. 8 is a schematic structural view of a medical testing device provided in the present application in a fourth embodiment;

FIG. 9 is a schematic structural diagram of a medical testing device according to a fifth embodiment of the present application;

FIG. 10 is a top view of a medical testing device provided herein in a sixth embodiment;

FIG. 11 is a top view of a medical testing device provided herein in a seventh embodiment;

FIG. 12 is a top view of a medical testing device provided herein in an eighth embodiment;

FIG. 13 is a top view of a medical testing device provided herein in a ninth embodiment.

Reference numerals:

1-a shell;

11-a transparent portion;

12-upper shell;

13-a lower shell;

14-edge sealing glue;

2-a data transmission component;

21-a data acquisition processing module;

22-an antenna;

23-a battery;

3-a measuring member;

31-a body portion;

32-glue material;

33-pH measuring means;

34-an occult blood measurement component;

35-pepsin measurement component;

36-trypsin measurement component;

4-an image component;

41-lens;

411-lens mount;

42-an image sensor;

43-lighting lamp;

431-LED structural member;

5-an infrared switch;

d1-effective imaging angle boundary;

d2-display image angle boundaries.

Detailed Description

For better understanding of the technical solutions of the present application, the following detailed descriptions of the embodiments of the present application are provided with reference to the accompanying drawings.

It should be understood that the embodiments described are only a few embodiments of the present application, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terminology used in the embodiments of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in the examples of this application and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.

It should be understood that the term "and/or" as used herein is merely one type of association that describes an associated object, meaning that three relationships may exist, e.g., a and/or B may mean: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the character "/" herein generally indicates that the former and latter related objects are in an "or" relationship.

It should be noted that the terms "upper", "lower", "left", "right", and the like used in the embodiments of the present application are described in terms of the angles shown in the drawings, and should not be construed as limiting the embodiments of the present application. In addition, in this context, it will also be understood that when an element is referred to as being "on" or "under" another element, it can be directly on "or" under "the other element or be indirectly on" or "under" the other element via an intermediate element.

The embodiment of the application provides a medical detection device, as shown in fig. 1 and fig. 2, the medical detection device comprises a housing 1 and a measurement component 3, wherein the housing 1 further comprises an upper shell 12 and a lower shell 13, and the upper shell 12 and the lower shell 13 are fixedly connected and enclose an inner cavity of the housing 1; the measuring unit 3 is mounted to an outer wall of the housing 1 for measuring a parameter of an external environment of the housing 1. When the medical detection equipment is used for detecting the digestive tract, the medical detection equipment can be used for detecting parameters of the digestive tract, such as pH value, occult blood concentration, pepsin concentration, trypsin concentration and the like.

Therefore, the medical detection device in the embodiment of the present application can detect various parameters (including pH, occult blood concentration, pepsin concentration, trypsin concentration, and the like) in the digestive tract by providing the measurement unit 3, and can improve the accuracy of the detection result of the medical detection device on the digestive tract.

Specifically, the measurement component 3 in the embodiment of the present application may include one or more of a pH measurement component 33, an occult blood measurement component 34, a pepsin measurement component 35, and a trypsin measurement component 36, wherein the pH measurement component 33 can be used to measure the pH of the external environment (e.g., digestive tract) of the shell 1, the occult blood measurement component 34 can be used to measure the presence and concentration of occult blood in the external environment (e.g., digestive tract) of the shell 1, the pepsin measurement component 35 is used to measure the concentration of pepsin in the external environment (e.g., digestive tract) of the shell 1, and the trypsin measurement component 36 is used to measure the concentration of trypsin in the external environment (e.g., digestive tract) of the shell 1.

Therefore, in the present embodiment, the measurement of each parameter of the digestive tract can be realized by the various measurement units 3, and the accuracy of the detection result of the medical detection device can be improved.

It should be noted that the medical detection apparatus in the embodiment of the present application does not necessarily include the four measurement components 3, and may include only one or any combination thereof.

Specifically, as shown in fig. 4, the measurement component 3 may include a main body 31 and a rubber material 32, wherein the rubber material 32 is a transparent rubber material and has biocompatibility, so that the main body 31 of the measurement component 3 can be adhered to the housing 1 of the medical detection apparatus through the rubber material 32. The adhesive material 32 may be a transparent adhesive tape, and is adhered to the transparent portion 11 of the housing 1. The transparent back adhesive may be, but is not limited to, a medical grade UV adhesive, a medical flash adhesive, or a medical back adhesive.

More specifically, as shown in fig. 5, the main body 31 of the measuring component 3 is connected to the outer wall of the housing 1 through the edge sealing glue 14, wherein the edge sealing glue 14 is disposed on the outer edge of the main body 31, so that the measuring component 3 is adhered to the housing 1 through the edge sealing glue 14. The edge sealing adhesive 14 may be, but is not limited to, a medical-grade UV adhesive, a medical flash adhesive, or a medical back adhesive.

In this embodiment, when the outer edge of the measurement component 3 is connected to the housing 1 through the edge sealing adhesive 14, the connection reliability between the measurement component 3 and the housing 1 can be further improved, and the risk that the measurement component 3 falls off from the housing 1 in the use and installation processes can be reduced.

In particular, the measuring means 3 may comprise a polyionic gel and a dye, which is capable of changing color. The measuring component 3 may be a thin film structure, and the shape thereof may be any shape such as a circle, a square, a polygon, etc., and the specific shape of the measuring component 3 is not limited in the present application.

In one possible design, the body portion 31 of the measuring part 3 includes polyion gel and dye, wherein the dye can change color, the polyion gel is a solid substance formed by cross-linking polymerization of polymer, and the dye is filled in the polyion gel, and the polyion gel and the dye ions have strong ionic interaction, so that the dye ions can be kept in the polyion gel.

The polyion gel contains an ion exchange membrane structure, and the ion exchange membrane is a polymer membrane which contains ionic groups and has selective permeability to ions in a solution. Meanwhile, when the measuring part 3 is located in a solution environment (e.g., the digestive tract of a human body), ions (e.g., hydrogen ions) of a substance to be measured in the solution can enter the polyion gel and combine with the dye in the polyion gel to discolor the dye. In addition, in the measuring part 3, the concentration of ions (e.g., hydrogen ions) of the substance to be measured in the solution is the same as the concentration of ions (e.g., hydrogen ions) of the substance to be detected in the polyion gel, and when the concentration of ions (e.g., hydrogen ions) of the substance to be detected in the solution increases, the ions (e.g., hydrogen ions) of the substance to be measured bound to the dye can diffuse into the polyion gel, thereby increasing the concentration of ions (e.g., hydrogen ions) of the substance to be measured, which corresponds to the concentration of one substance to be measured (e.g., the concentration of; when the concentration of ions (e.g., hydrogen ions) of the substance to be measured in the solution decreases, the ions (e.g., hydrogen ions) of the substance to be measured in the polyion gel can diffuse into the solution, thereby decreasing the concentration of ions (e.g., hydrogen ions) of the substance to be measured bound to the dye, corresponding to the concentration of another substance to be measured (e.g., the concentration of hydrogen ions, i.e., the pH of the solution).

Therefore, in the present embodiment, the dye in the measuring part 3 can be bonded to or separated from the ions (for example, hydrogen ions) of the substance to be measured to form a dynamic equilibrium, and continuous measurement of the concentration of the substance to be measured can be realized.

Based on this, in the present embodiment, the measurement component 3 including the polyion gel and the dye can be conveniently integrated (e.g. adhered) with the medical detection device (e.g. capsule endoscope), and the integrated component is compatible with the hardware of the medical detection device, and does not need to perform secondary packaging, and only needs to modify the related software to perform ph measurement while performing endoscopy, so as to improve the detection accuracy. Meanwhile, by additionally arranging the polyion gel, ions of the substance to be detected in the solution can penetrate through the polyion gel and be combined with the dye, and ions of the substance to be detected combined with the dye can also penetrate through the polyion gel, so that the measuring component 3 can form dynamic balance with the ions of the substance to be detected, and the continuous measurement of the concentration of the substance to be detected is realized. In addition, the measuring component 3 is also beneficial to realizing industrialization and reducing cost.

In a specific embodiment, when the medical detection apparatus is used for measuring the pH of the digestive tract, the measuring part 3 comprises at least a pH measuring part 33, wherein the body part 31 of the pH measuring part 33 may comprise polyion gel and pH sensitive dye, wherein the pH sensitive dye has different colors when the concentration of hydrogen ions in the solution is different.

In the field of medical instruments, when the pH value inside a human body is detected, the pH value is mainly detected in the prior art through the following two modes, namely a pH electrode, the pH value of an environment to be detected can be directly detected by making a material sensitive to hydrogen ions into the electrode and utilizing an electrochemical principle, and the precision is high, such as an antimony electrode. The other scheme is to judge the pH value of the environment to be detected through color change, and the precision is low, such as traditional pH test paper, pH indicator and the like.

When pH is measured by an electrochemical method, the sensor is complex, a reference electrode and a test electrode need to be packaged together, and an ion channel needs to be ensured between the reference electrode and the test environment. For a conventional usage scenario, glass electrodes, antimony electrodes, and hydrogen ion sensitive field effect transistors (H)⁺SFET) can meet the application requirements. However, for the measurement of the pH value of the digestive tract of a human body, the integration of the pH electrode on the capsule endoscope is extremely difficult and is not easy to realize. In addition, potential biological toxicity exists if antimony electrodes are used as pH electrodes.

Methods for measuring pH by color change have long been available, but such methods are not capable of continuous measurement of different pH environments, nor are they capable of continuous pH measurement integrated into a capsule endoscopic device.

For the above reasons, in the field of medical equipment, there is no technology capable of integrating an endoscope device with a pH measurement sensor, or in the current technology, the equipment formed by integrating the endoscope device with the pH measurement sensor has low reliability and high cost.

In this embodiment, the medical detection device in the present application can acquire pH information of the digestive tract, that is, the medical detection device integrates the pH measurement component 33, and meanwhile, by changing the structure of the pH measurement component 33, the integration process can be simplified, and the integration cost can be reduced. The pH measuring component 33 including the polyion gel and the pH sensitive dye can be conveniently integrated (e.g., adhered) with the medical detection device (e.g., capsule endoscope) without using an electrochemical electrode, and is compatible with hardware of the medical detection device after integration without performing secondary packaging, and only related software needs to be modified to perform pH measurement while performing endoscopy, so as to improve the detection accuracy. Meanwhile, by additionally arranging the polyion gel, hydrogen ions in the solution can penetrate through the polyion gel and be combined with the pH sensitive dye, and hydrogen ions combined with the pH sensitive dye can also penetrate through the polyion gel, so that the pH measuring part 33 can form dynamic balance with the hydrogen ions, and the continuous measurement of the pH value is realized. Besides the acidity and alkalinity of the stomach, the pH measuring unit 33 can also measure the acidity and alkalinity of organs such as the oral cavity and the intestinal tract, and can display different colors according to the difference of the acidity and alkalinity of each organ. In addition, the pH measuring unit 3 contributes to industrialization and cost reduction.

Specifically, by changing the amount or kind of the pH sensitive dye in the pH measuring part 33, the span and accuracy of the pH measuring part 33 can be changed. For example, one kind of pH measurement component 33 can satisfy the measurement of pH values of 1, 5, 7, and 8, and the other kind of pH measurement component 33 can satisfy the measurement of pH values of 2, 3, 4, and 6, so when the medical measurement component includes the above two kinds of pH measurement components 33, the pH measurement component can satisfy the measurement of pH values within a range of 1 to 8, and can satisfy the resolution of pH values of 0.5 to 1. The two pH measuring parts 33 are different in the type of the sensitive dye, and the polyion gels of the two pH measuring parts can be the same.

In another embodiment, when the medical detection apparatus is used for measuring the presence and concentration of occult blood in the digestive tract, the measurement component 3 at least comprises an occult blood measurement component 34, wherein the body portion 31 of the occult blood measurement component 34 may comprise polyion gel and methylene blue dye, wherein the methylene blue dye has different colors when the concentration of hemoglobin in the solution is different.

In the field of medical equipment, there are two main schemes for detecting the occult blood in the digestive tract. The first scheme is a blood occult bead method, which has the basic principle that a capsule with fine lines is swallowed, the capsule absorbs gastric juice at the tail part and is pulled out through the fine lines, then a color developing agent is dripped on the capsule stained with the gastric juice, and color change is observed to judge whether occult blood is generated. The second scheme is to detect the occult blood condition of the digestive tract by detecting the bleeding condition in the excrement through an occult blood test paper.

The first scheme is only suitable for detecting occult blood in the upper digestive tract and belongs to invasive detection, and discomfort reactions such as vomiting and the like can be caused in the detection process. The second scheme is only suitable for detecting occult blood in the lower digestive tract, especially for detecting the colon and rectum, and is easy to cause the false positive phenomenon of detection due to the influence of hemorrhoids and the like.

In this embodiment, when the occult blood measuring unit 34 including polyion gel and methylene blue dye is used, the polyion gel and the methylene blue dye ion have strong ionic interaction, so that the methylene blue dye ion is kept in the polyion gel without leaking, and the methylene blue dye is a biological stain and has an oxidation effect on hemoglobin, in the reaction process, the methylene blue dye is reduced by hemoglobin and then is converted from blue to colorless, and according to the difference of hemoglobin concentration, the depth of blue is different, and the occult blood condition can be quantitatively detected through color change.

In this example, methylene blue dye is a non-toxic dye, and its oxidized form is blue and its reduced form is colorless. Under the environment of high-concentration hemoglobin, the methylene blue dye has stronger reducing capability in cells due to the metabolism of the cells, under the action of glucose-6-phosphate dehydrogenase, the oxidation type of blue can be changed into colorless or light yellow reduction type, and under the environment of low-concentration hemoglobin, the cells in the environment have no reducing capability or extremely weak reducing capability, and at the moment, the methylene blue dye is blue or light blue. Thus, when the methylene blue dye appears blue or bluish, it indicates a low concentration of hemoglobin in the environment (e.g., the digestive tract), and when the methylene blue dye appears colorless or yellowish, it indicates a high concentration of hemoglobin in the environment (e.g., the digestive tract).

The occult blood measuring unit 34 in the present embodiment can continuously measure the occult blood concentration in different organs, for example, the stomach and the intestinal tract.

Therefore, the medical detection apparatus in the embodiment of the present application integrates the occult blood measurement component 34, and meanwhile, by changing the structure of the occult blood measurement component 34, the integration process can be simplified, and the cost can be reduced, and more importantly, the medical detection apparatus can realize noninvasive detection, and the measurement accuracy is high.

In yet another embodiment, when the medical detection device is used for measuring pepsin concentration in the digestive tract, the measuring part 3 comprises at least a pepsin measuring part 35, wherein the body part 31 of the pepsin measuring part 35 may comprise a polyion gel and a bromophenol blue dye, wherein the bromophenol blue dye has different colors when the concentration of pepsin in a solution (e.g. digestive tract) is different.

Pepsin in human gastric juice becomes a biological marker of gastritis and gastric cancer diseases, and when intestinal metaplasia, atypical hyperplasia and gastric cancer occur, pepsin secretion is reduced; when the helicobacter pylori is infected or diseases such as gastric ulcer and duodenal ulcer exist, the pepsin value is increased. At present, a large number of statistical analyses indicate that the content change of the serum pepsinogen is related to stomach diseases, and the detection of the serum pepsinogen is considered to have an important role in early diagnosis of the gastric cancer.

At present, the prior art mainly detects the content of pepsin through three ways, the first way is serum collection and in-vitro detection, and the method analyzes by collecting serum of a detected person, but the method collects a sample in vivo and detects in vitro to analyze the specific content of pepsin, so that the detected pepsin is single detection, and has limitation on real-time monitoring of the content of pepsin in gastric juice; in addition, the pepsin only plays a role in an acid environment, and the pepsin loses activity when the pH value is more than 6, so that the pepsin is easily influenced by the environment under an in vitro environment to cause inaccurate test results. The second one relies on gastroscopy to confirm diagnosis, but gastroscopy has certain pain, high cost, limits to the level of doctors and has low patient acceptance. The third is a detection method of a pepsin chemiluminescence immunoassay kit, which adopts the pepsin chemiluminescence immunoassay kit, and the kit comprises a pepsin antigen calibrator, a sample collecting solution, a sample diluent, a pepsin antibody coated microporous plate, a pepsin antibody marker, chemiluminescence substrate solution and concentrated washing solution. The kit can detect the content of pepsin in gastric juice, esophageal contents and laryngeal secretions of pharynx, judge whether gastroesophageal reflux exists according to whether the pepsin can be detected, and judge the treatment effect and the disease change of stomach lesions according to the content of the pepsin. Although the method can detect the pepsin, the process is complex, the requirements on operators and detection equipment are high, and the cost is not low.

In the embodiment of the present application, when the pepsin measuring unit 35 including the polyion gel and the bromophenol blue dye is used, the polyion liquid gel and the bromophenol blue dye ions have strong ionic interaction, so that the bromophenol blue dye ions are kept in the gel and do not leak. The bromophenol blue dye is a biological staining agent, under the condition of different pH values, the bromophenol blue dye is combined with pepsin by means of non-covalent bonds, a hydrophobic core of the pepsin is combined with a nonpolar group of the bromophenol blue dye, the volume of the combined aggregate is larger than that of the bromophenol blue dye, so that the molar absorption coefficient after combination is changed, light scattering signals are changed, different colors are displayed, and the signal intensity of the bromophenol blue dye is in a proportional relation with the number of particles in a unit volume, namely the concentration of the pepsin, so that the detection of the concentration of the pepsin can be realized. In the detection process, the bromophenol blue dye in the pepsin measuring part 35 shows different colors for the concentrations of the pepsin with different concentrations, and the concentrations can be quantitatively detected through color change.

In addition, since pepsin is only present in an acidic environment, and is inactivated and denatured in a neutral or alkaline environment, pepsin is only present in the stomach, and based on this, the pepsin measuring part 35 can be used only for measuring the pepsin concentration in the stomach, and cannot be used in other organs (because pepsin is inactivated in other organs). During detection, pepsin in the stomach is combined with bromophenol blue dye, so that the molar absorption coefficient is changed, the light scattering signal is changed, the color is displayed, and the color and the concentration of the pepsin are in a certain proportion relation, so that the detection of corresponding protein is realized. The pepsin measuring component 35 has different color changes in a range from low concentration to high concentration in a detection environment of an acidic environment, and has a certain continuous detection function; but it does not have continuous detection characteristics when the environment of the solution changes (e.g., from the stomach to the duodenum).

Therefore, the medical detection device in the embodiment of the present application integrates the pepsin measuring part 35, and meanwhile, by changing the structure of the pepsin measuring part 35, the integration process can be simplified, and the cost can be reduced, and more importantly, the medical detection device can realize noninvasive detection, and the measurement accuracy is high.

In yet another embodiment, when the medical detection apparatus is used for measuring trypsin concentration in the digestive tract, the measuring means 3 comprises at least a trypsin measuring means 36, wherein the body portion 31 of the trypsin measuring means 36 may comprise a polyion gel and a bromocresol purple dye, wherein the bromocresol purple dye has different colors when the concentration of trypsin concentration in a solution (e.g. the digestive tract) is different.

In the embodiment of the present application, when the trypsin measuring part 36 including the polyion gel and the bromocresol purple dye is used, the bromocresol purple dye ions can be kept in the gel without leaking due to strong ionic interaction between the polyion liquid gel and the bromocresol purple dye ions. Under different pH values, the bromocresol purple dye is combined with trypsin through a non-covalent bond, a hydrophobic core of the trypsin is combined with a nonpolar group of the bromocresol purple dye, the volume of a combined aggregate is larger than that of the bromocresol purple dye, so that the combined molar absorption coefficient is changed, a light scattering signal is changed, different colors are displayed, and the signal intensity of the bromocresol purple dye is in a proportional relation with the number of particles in unit volume, namely the concentration of the trypsin, so that the concentration of the trypsin can be detected. In the detection process, the bromocresol purple dye in the trypsin measuring part 36 shows different colors for the trypsin concentrations with different concentrations, and the concentrations can be quantitatively detected through color change.

In addition, since trypsin is only present in a weak alkaline environment, an acidic environment is inactivated and denatured, trypsin is present in pancreas, and trypsin in pancreas can flow to duodenum along with pancreatic juice, based on which the trypsin measuring part 36 can be used only for measuring trypsin concentration in pancreas and duodenum, and cannot be used in other organs (because trypsin is inactivated in other organs). During detection, trypsin is combined with bromocresol purple dye, so that the molar absorption coefficient is changed, the light scattering signal is changed, the color is displayed, and the color and the concentration of the trypsin are in a certain proportion relation, so that the detection of corresponding protein is realized. The trypsin measuring component 36 has different color development changes in a range from low concentration to high concentration in a detection environment of a weak alkali environment, and has a certain continuous detection function; but it does not have continuous detection characteristics when the solution environment changes (e.g., from duodenum to jejunum).

Therefore, the medical detection device in the embodiment of the present application integrates the trypsin measuring part 36, and meanwhile, by changing the structure of the trypsin measuring part 36, the integration process can be simplified, and the cost can be reduced, and more importantly, the medical detection device can realize noninvasive detection, and the measurement accuracy is high.

In a specific embodiment, the medical detection device can comprise a plurality of measurement components 3, the measuring ranges of the measurement components 3 are not identical, and/or the resolutions of the measurement components 3 are not identical, and the combination of the plurality of measurement components 3 can meet the measurement of the concentration of various parameters to be measured, thereby improving the measurement accuracy and the measurement range. Meanwhile, when the device comprises a plurality of measuring components 3, the problem that the parameters to be measured cannot be measured or the measuring result is inaccurate due to the failure of a single measuring component 3 can be avoided. For example, the medical detection device may include a plurality of pH measurement components 33, and the ranges of the pH measurement components 33 are not completely the same, and/or the resolutions of the pH measurement components 33 are not completely the same, so that by combining a plurality of pH measurement components 33, the measurement of multiple pH values can be satisfied, the measurement accuracy and the measurement range can be improved, and the failure of a single pH measurement component 33 to measure pH value information or inaccurate measurement results can be avoided.

The plurality of measuring units 3 may be the same type of measuring unit 3, may be different types of measuring units 3, or may be a combination of a plurality of types of measuring units 3. For example, as shown in the embodiment of fig. 6, the medical test device includes a pH measuring part 33, a occult blood measuring part 34, a pepsin measuring part 35, and a trypsin measuring part 36 at the same time, thereby enabling the medical test device to be used for measuring pH, occult blood concentration, pepsin concentration, and trypsin concentration of the digestive tract. In addition, the pH measuring part 33, the occult blood measuring part 34, the pepsin measuring part 35, and the trypsin measuring part 36 may each include one or more so as to improve the accuracy of the measurement. The shape of each of the measuring members 3 may be circular.

In the embodiment shown in fig. 7, the medical test device comprises a pepsin measuring part 35 and a trypsin measuring part 36, thereby enabling the medical test device to be used for measuring pepsin and trypsin concentrations. In addition, the pepsin measuring part 35 and the trypsin measuring part 36 described above may each include one or more so as to improve the accuracy of the measurement. The shape of each of the measuring members 3 may be rectangular.

In the embodiment shown in fig. 8, the medical test device comprises a pH measurement component 33 and an occult blood measurement component 34, thereby enabling the medical test device to measure pH and occult blood concentration. In addition, each of the pH measuring part 33 and the occult blood measuring part 34 may include one or more so as to improve the accuracy of the measurement. The shape of each of the measuring members 3 may be circular.

In the above embodiments, as shown in fig. 1, in the medical examination apparatus, at least a portion of the housing 1 is a transparent portion 11, and the transparent portion 11 is made of a transparent material having biocompatibility, that is, the environment outside the housing 1 can be observed from the inside of the housing 1 through the transparent portion 11.

Meanwhile, the medical examination device further includes an image component 4, as shown in fig. 1 to 3, the image component 4 is located in an inner cavity of the housing 1, and specifically includes a lens 41, an image sensor 42 and an illumination lamp 43, the lens 41 can receive light of an environment (for example, a digestive tract of a human body) outside the housing 1 through the transparent portion 11 of the housing 1, the image sensor 42 is configured to convert a light signal received by the lens 41 into an electrical signal, the illumination lamp 43 is configured to illuminate, and specifically may be an LED lamp, and the illumination lamp 43 includes an LED structural component 431, so that the image component 4 can shoot and observe a picture of the environment outside the housing 1 through an optical imaging principle. Based on this, the medical detection apparatus in the embodiment of the present application may be an endoscope.

Further, as shown in fig. 2 and fig. 3, the medical examination apparatus further includes a data transmission assembly 2, the data transmission assembly 2 is located in the inner cavity of the housing 1, and specifically includes a data acquisition processing module 21, an antenna 22 and a battery 23, wherein the battery 23 supplies power to the image component 4 and each component in the data transmission assembly 2, the data acquisition processing module 21 is electrically connected or in signal connection with the image component 4, so as to be able to identify and process information in the image component 4, and at the same time, the antenna 22 is used for transmitting the obtained information to an external receiving device.

Specifically, the medical detection equipment can be a capsule endoscope, during processing, a circuit board of the capsule endoscope is firstly assembled and connected with the image component 4 and the data transmission component 2, when the components are connected, the components are mainly bonded through UV (ultraviolet) glue to form a capsule core with a photographing function, then the capsule core is filled into the shell 1, the capsule core is firstly filled into the lower shell 13, then the upper shell 12 is filled, and the LED structural component 431 is clamped between the upper shell 12 and the lower shell 13, so that the LED structural component 431 is fixed in the position inside the capsule, the capsule core is further fixed inside the shell 1, and the assembly of the capsule endoscope is completed.

Therefore, when the medical detection device is arranged in each part of the human body, the measurement component 3 can display different colors according to the parameters to be measured with different concentrations, the concentration of the parameters to be measured can be quantitatively detected through color change, the color change can be judged by acquiring the picture of the measurement component 3 through the lens 41 of the image component 4, and the color information is sent to the external receiving device through the data transmission component 2 and can be displayed in real time, so that the medical detection device is helpful for detection. Meanwhile, the medical detection device can also shoot and observe pictures of the external environment of the medical detection device through the lens 41 of the imaging part 4, and the picture information can be sent to an external receiving device through the data transmission component 2 and can be displayed in real time, so that the health condition of the part can be judged.

The medical detection equipment in the embodiment of the application can observe the health condition of the alimentary canal mucous membrane by arranging the image component 4 and the data transmission component 2, can measure the concentration of parameters to be measured in the alimentary canal by arranging the measuring component 3, namely, the medical detection equipment integrates the endoscope device and the measuring component 3, and meanwhile, the structure and the type of the measuring component 3 are changed, so that the process of integrating the two components can be simplified, and the integration cost is reduced.

Specifically, as shown in fig. 3, the lens 41 is installed in the inner cavity of the housing 1, the lens 41 has an effective imaging angle α 1, and the transparent portion 11 of the housing 1 can cover the space where the effective imaging angle α 1 is located, so that the view of the lens 41 is not blocked. Meanwhile, as shown in fig. 3, the image sensor 42 has a display image angle α 2, and the transparent portion 11 of the housing 1 can also cover the space where the display image angle α 2 is located, so that the imaging area of the image sensor 42 is not blocked.

Meanwhile, when the lens 41 and the image sensor 42 are installed, α 1 > α 2 is satisfied, that is, although the lens 41 can capture a picture in the range corresponding to α 1, and the range corresponding to α 1 has the effective imaging angle boundary D1, the image sensor 42 can display the picture in the range corresponding to α 2, and the range corresponding to α 2 has the display image angle boundary D2. For example, the above-described effective imaging angle α 1 may be 140 °, and the display image angle α 2 may be 135 °.

Based on this, in the first embodiment, as shown in fig. 10, the above-mentioned measuring unit 3 is installed in the transparent part 11, and is located in the space between the effective imaging angle α 1 and the display image angle α 2, that is, the measuring unit 3 is located between the effective imaging angle boundary D1 and the display image angle boundary D2, and a plurality of measuring units 3 may be included between the effective imaging angle boundary D1 and the display image angle boundary D2, and the plurality of measuring units 3 may be of the same type or different types, as in the embodiment shown in fig. 10, a pH measuring unit 33 and a pepsin measuring unit 35 are provided between the effective imaging angle boundary D1 and the display image angle boundary D2, and both may be of arc-shaped structures.

At this time, the measuring part 3 cannot be observed in the observation area of the image sensor 42, but the measuring part 3 is located within the imaging range of the lens 41, and therefore, the lens 41 and the data transmission component 2 can read the color information of the measuring part 3 and can transmit the color information to an external receiving device via the antenna 22, thereby displaying the color information by the external receiving device and obtaining the density value of the parameter to be measured from the color information. Since the measurement unit 3 does not occupy the imaging area of the image sensor 42, a complete image of the mucosa of the digestive tract can be observed, and the image can be transmitted to and displayed on an external receiving device via the antenna 22 so as to observe the health condition of the digestive tract.

In another embodiment, as shown in fig. 11, the measuring component 3 is installed in the transparent portion 11 and located in the space occupied by the display image angle α 2, that is, the measuring component 3 is located inside the display image angle boundary D2 and close to the display image angle boundary D2, so that the measuring component 3 can be prevented from occupying the middle position of the display image range, and the image obstruction caused by the measuring component 3 can be reduced. At this time, the measurement member 3 is located within the imaging area of the image sensor 42, the image sensor 42 transmits color information of the measurement member 3 to an external receiving apparatus so that the user can observe the measurement member 3 displayed by color, and the color information can be transmitted to the external receiving apparatus via the antenna 22 so that the density of the parameter to be measured is displayed at the external receiving apparatus. Therefore, the medical detection device in the embodiment can collect the concentration of the parameter to be measured of the alimentary canal while observing the alimentary canal mucosa.

One or more measuring units 3 may be disposed inside the display image angle boundary D2 of the medical examination apparatus, and the plurality of measuring units 3 may be of the same type or different types, as shown in fig. 11, in the embodiment, the occult blood measuring unit 34 and the trypsin measuring unit 36 are disposed inside the display image angle boundary D2, and both of them may be of an arc-shaped structure and are close to the display image angle boundary D2.

In yet another embodiment, the measuring unit 3 is mounted on the transparent portion 11 and located in the space occupied by the display image angle α 2, i.e. the measuring unit 3 is located inside the display image angle boundary D2, and the measuring unit 3 may be located in the middle of the space occupied by the display image angle α 2.

At this time, the measurement member 3 is located within the imaging area of the image sensor 42, the image sensor 42 transmits color information of the measurement member 3 to an external receiving apparatus so that the user can observe the measurement member 3 displayed by color, and the color information can be transmitted to the external receiving apparatus via the antenna 22 so that the density of the parameter to be measured is displayed at the external receiving apparatus. Therefore, the medical detection device in the embodiment can collect the concentration of the parameter to be measured of the alimentary canal while observing the alimentary canal mucosa. Meanwhile, when the measuring component 3 is positioned in the middle of the space occupied by the display image angle alpha 2, the user can conveniently observe the measuring component 3, and the shielding is reduced, so that the concentration value of the parameter to be measured is more accurately acquired.

The medical examination apparatus may be provided with one or more measurement units 3, and the plurality of measurement units 3 may be of the same type or different types, as in the embodiment shown in fig. 12, a plurality of pepsin measurement units 35 and trypsin measurement units 36 are provided between the display image angle boundary D2 and the effective imaging angle boundary D1, and each of the pepsin measurement unit 35 and the trypsin measurement unit 36 is located at a corner of the field of view, the pH measurement unit 33 is provided within the display image angle boundary D2, and the pH measurement unit 33 is located at the middle of the space occupied by the display image angle α 2. The measuring member 3 may be of circular configuration.

Meanwhile, as shown in fig. 12, the medical detection apparatus may further include an infrared switch 5, and the infrared switch 5 may function to turn on the measurement part 3, so that the measurement part 3 of the medical detection apparatus can start to operate.

In the embodiment shown in fig. 10-12, the image angle boundary D2 and the effective imaging angle boundary D1 of the camera 41 of the imaging component 4 can be circular and concentric. In the embodiment shown in fig. 13, the effective imaging angle boundary D1 of the camera 41 of the camera unit 4 may be square, and the image angle boundary D2 may be circular, and at this time, when the measuring unit 3 is located between the image angle boundary D2 and the effective imaging angle boundary D1, it may be located at four corners of the effective imaging angle boundary D1.

In a specific embodiment, the arrangement of the plurality of measuring parts 3 on the outer wall of the housing 1 is a divisional arrangement or an alternate arrangement. The arrangement of the subareas is that the outer wall of the shell 1 is divided into a plurality of areas, and each area is used for arranging one or more measuring components 3 of the same type. For example, the transparent part 11 is divided into two sub-parts on the left and right on average by taking the infrared switch 5 as a reference, and one or more measuring components 3 of the same type can be arranged in each sub-part; for example, in fig. 11, the transparent part 11 is divided into two sub-parts, i.e., a left sub-part and a right sub-part, and then one trypsin measuring part 36 is placed in the left sub-part and one occult blood measuring part 34 is placed in the right sub-part. The partition arrangement is to divide the outer wall of the shell 1 into a plurality of areas, each area is used for arranging a plurality of measuring components 3 of different types, and each type of measuring component 3 can be one or more. For example, the transparent part 11 is rotated 90 degrees clockwise with respect to the infrared switch 5⁰The division interval is divided into four sub-parts on average, and each sub-part can be provided with a plurality of measuring components 3 of different types; for example, in FIG. 12, the transparent part 11 is divided into [0, 90 ] in the clockwise direction on average with respect to the infrared switch 5⁰]、[90⁰，180⁰]、[180⁰，270⁰]And [270⁰，360⁰]After four sub-sections, one trypsin measuring component 36 and one pepsin measuring component 35 are placed in each sub-section. The alternating arrangement can maximize the detection result and optimize the detection when the solution (such as liquid in gastrointestinal tract) is less and only part of the shell 1 is immersed in the solution.

On the other hand, in the medical examination apparatus, as shown in the embodiments of fig. 6 to 8, the image unit 4 includes a lens 41, and the lens 41 is used for taking a picture of the digestive tract and acquiring color information of the measurement unit 3. In the present embodiment, the lens 41 may acquire an imaging image of the measurement component 3, the imaging image of the measurement component 3 is transmitted together with the picture of the digestive tract to an external receiving device via the data transmission assembly 2, and the external receiving device may recognize and display the concentration of the corresponding parameter to be detected according to the imaging image of the measurement component 3.

Of course, as shown in fig. 9, the medical examination apparatus may further include two image components 4, specifically, the housing 1 thereof includes a first end portion and a second end portion (an upper shell 12 and a lower shell 13) which are oppositely disposed along the axial direction, and the first end portion and the second end portion may be provided with transparent portions 11, and at the same time, the two image components 4 are respectively disposed corresponding to the two transparent portions 11, wherein the medical examination apparatus may be a dual-lens capsule endoscope.

Specifically, the above-mentioned measuring parts 3 may be all mounted on the outer wall of the first end portion, or may be all mounted on the outer wall of the second end portion, in this case, one imaging part 4 of the medical detection apparatus is used for measuring the concentration of the parameter to be measured, and the other is used for observing and taking pictures.

Or, in the medical detection device, the outer wall of the first end of the housing 1 is provided with a first measurement component, the outer wall of the second end is provided with a second measurement component, the first end can be provided with one or more first measurement components, the second end can be provided with one or more second measurement components, the types of the first measurement component and the second measurement component can be the same or different, the measuring ranges can be the same or different, and the equivalent ranges are different, so that the medical detection device can simultaneously meet the detection of different concentration ranges.

In the embodiment shown in fig. 9, the first end and the second end of the housing 1 are provided with the cameras 41, and the cameras 41 are located at the transparent parts 11 of the first end and the second end, and at the same time, the first end can be provided with the pH measuring part 33 and the pepsin measuring part 35, and the second end can be provided with the occult blood measuring part 34 and the trypsin measuring part 36, and at this time, the first end of the medical detection device can be used for taking pictures of the digestive tract and measuring the pH value and the concentration of pepsin in the digestive tract, and the second end of the medical detection device can be used for taking pictures of the digestive tract and measuring the occult blood concentration and the concentration of trypsin in the digestive tract.

It should be noted that the medical detection apparatus described above may be a capsule endoscope, and of course, other medical detection apparatuses may also be used, such as other image measurement apparatuses like an electronic endoscope.

In a particular embodiment, when the medical examination apparatus is a capsule endoscopic device, it comprises at least one measuring unit 3 for applying the capsule endoscope to the surface of the transparent portion 11 of the capsule housing 1. Wherein, this measuring part 3 can be the loop configuration, inside and outside footpath size can be 5mm and 6mm respectively, thickness can be 40um, of course, its size and thickness can also be other numerical values, and this measuring part 3's body part 31 pastes in transparent portion 11 surface through medical UV glue (glue material 32), measuring part 3 can be in effective formation of image angle alpha 1 and display image angle alpha 2 between, do not influence the image display of normal user interface, the measuring result of measuring part 3 is observed to accessible external receiving equipment.

In another embodiment, the endoscopic capsule device comprises a measuring unit 3 for applying the endoscopic capsule to the surface of the transparent portion 11 of the capsule shell 1. Wherein, the measuring part 3 can be strip-shaped, the length and width dimensions can be respectively 6mm and 2mm, the thickness can be 50um, and of course, the dimension and the thickness can also be other numerical values. The main body 31 of the measuring component 3 can be adhered to the surface of the transparent part 11 of the housing 1 by medical adhesive (glue material 32), and the measuring component 3 can be within the effective imaging angle α 1.

In addition, the embodiment of the application also provides a measurement component 3 of the medical detection component, the measurement component 3 comprises polyion gel and dye, wherein the dye is a substance which can have different colors according to different concentrations of parameters to be measured, the polyion gel is a solid substance formed by cross-linking and polymerizing polymers, and the dye is filled in the polyion gel, and the polyion gel and the dye ions have stronger ion interaction, so that the dye ions can be kept in the polyion gel. When the device works, ions of a substance to be measured in the environmental solution can pass through the polyion gel and change color after being combined with the dye, so that the concentration of the parameter to be measured of the environmental solution can be displayed.

The above description is only exemplary of the present application and should not be taken as limiting the present application, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present application should be included in the scope of protection of the present application.

Claims (22)

1. A medical testing device, comprising:

a housing (1);

a measuring part (3) mounted on an outer wall of the housing (1), the measuring part (3) including a polyion gel and a dye, the dye being filled in the polyion gel;

the measuring component is used for measuring the concentration of the parameter to be measured in the environment outside the shell (1), and the dye can change color when the concentration of the parameter to be measured is different.

2. The medical testing device according to claim 1, characterized in that the measuring means (3) comprises one or more of a pH measuring means (33), a occult blood measuring means (34), a pepsin measuring means (35), a trypsin measuring means (36).

3. The medical detection device according to claim 2, wherein the dye of the pH measurement component (33) is a pH sensitive dye that is capable of changing color in environments with different pH values.

4. The medical detection device according to claim 3, wherein hydrogen ions in the environment outside the housing (1) can enter the pH measurement member (33) through the polyionic gel, and hydrogen ions in the pH measurement member (33) can enter the environment outside the housing (1) through the polyionic gel;

the pH sensitive dye can bind to or separate from hydrogen ions to form a dynamic equilibrium.

5. The medical detection device according to claim 2, wherein the dye of the occult blood measurement component (34) comprises a methylene blue dye, which is capable of changing color in environments with different occult blood concentrations.

6. The medical detection device according to claim 5, characterized in that hemoglobin in the environment outside the housing (1) is capable of binding and reacting with the polyionic gel and the methylene blue dye in the occult blood measurement component (34);

under the effect of hemoglobin, through redox reaction, the methylene blue dye can show the colour, and the concentration of hemoglobin is different, the colour that the methylene blue dye shows is different.

7. The medical detection device according to claim 2, wherein the dye of the pepsin measuring part (35) comprises a bromophenol blue dye, which is capable of changing color in environments with different pepsin concentrations.

8. The medical detection device according to claim 7, characterized in that pepsin in the environment external to the housing (1) is able to bind to the polyionic gel and the bromophenol blue dye in the pepsin measuring part (35);

and the combined light scattering signal of the bromophenol blue dye changes, different colors are displayed, and the colors of the bromophenol blue dye are different when the concentration of pepsin is different.

9. The medical detection device of claim 2, wherein the dye of the trypsin measuring component (36) comprises a bromocresol purple dye that is capable of changing color in environments with different trypsin concentrations.

10. The medical detection device according to claim 9, wherein trypsin in the environment outside the housing (1) is capable of binding to the polyion gel and the bromocresol purple dye in the trypsin measuring part (36);

the volume of the combined bromocresol purple dye is changed, the light scattering signal of the bromocresol purple dye is changed, different colors are shown, and the colors of the bromocresol purple dye are different when the concentration of trypsin is different.

11. The medical examination device according to claim 2, wherein the plurality of measurement members (3) are arranged in a divisional arrangement or an alternate arrangement on the outer wall of the housing (1).

12. The medical examination device of any one of claims 1-11, characterized in that the medical examination device comprises a plurality of the measuring members (3);

the measuring ranges of the measuring elements (3) are not identical and/or the resolutions of the measuring elements (3) are not identical.

13. The medical examination device of any one of claims 1-11, wherein the housing (1) comprises a transparent portion (11);

the medical detection equipment further comprises an image part (4), wherein the image part (4) is located in the inner cavity of the shell (1), and the image part (4) can observe the environment outside the shell (1) through the transparent part (11).

14. The medical detection device according to claim 13, wherein the housing (1) comprises a first end and a second end arranged opposite each other in an axial direction, the first end and the second end each comprising the transparent portion (11);

the medical detection equipment comprises two image parts (4), wherein the two image parts (4) are respectively arranged corresponding to the two transparent parts (11);

the measuring part (3) is mounted on the outer wall of the first end part or the second end part; alternatively, the first and second electrodes may be,

the medical detection device at least comprises a first measurement component (3) and a second measurement component (3), the range of the first measurement component (3) is different from that of the second measurement component (3), one of the first measurement component (3) and the second measurement component (3) is installed on the outer wall of the first end part, and the other one of the first measurement component (3) and the second measurement component (3) is installed on the outer wall of the second end part.

15. The medical examination device of claim 13, further comprising a data transmission assembly (2);

the image component (4) comprises a lens (41) and an image sensor (42), wherein the lens (41) is connected with the image sensor (42) through a mechanical structure and/or glue;

the image sensor (42) is electrically or signal-connected with the data transmission component (2), and the lens (41) is connected with the data transmission component (2) through a mechanical structure and/or glue.

16. The medical detection apparatus according to claim 15, wherein the lens (41) is mounted in an inner cavity of the housing (1), and the lens (41) has an effective imaging angle α 1, and the transparent portion (11) can cover a space where the effective imaging angle α 1 is located;

the image sensor (42) is provided with a display image angle alpha 2, the transparent part (11) can cover the space where the display image angle alpha 2 is located, and alpha 1 is larger than alpha 2;

the measuring component (3) is arranged on the outer wall of the shell (1) and is positioned in a space between the effective imaging angle alpha 1 and the display image angle alpha 2;

the data transmission assembly (2) is capable of reading the data of the measuring component (3).

17. The medical detection apparatus according to claim 15, wherein the lens (41) is mounted in an inner cavity of the housing (1), and the lens (41) has an effective imaging angle α 1, and the transparent portion (11) can cover a space where the effective imaging angle α 1 is located;

the image sensor (42) is provided with a display image angle alpha 2, the transparent part (11) can cover the space where the display image angle alpha 2 is located, and alpha 1 is larger than alpha 2;

the measuring component (3) is arranged on the outer wall of the shell (1) and is positioned in a space occupied by the display image angle alpha 2;

the image sensor (42) is capable of recognizing data of the measuring component (3).

18. The medical examination device according to claim 17, characterized in that the measuring means (3) is located in the middle of the space occupied by the display image angle α 2.

19. The medical examination device of any one of claims 1 to 11, wherein the measurement member (3) is affixed to the outer wall of the housing (1) by a transparent glue material (32).

20. The medical detection device according to claim 19, wherein the measurement member (3) is further adhered to the outer wall of the housing (1) by a sealing glue (14), and the sealing glue (14) covers the outer edge of the measurement member (3).

21. The medical examination device of any one of claims 1 to 11, wherein the housing (1) is of a capsule-like construction;

the medical detection equipment is a capsule endoscope.

22. A measuring part of a medical examination apparatus, characterized in that the measuring part (3) comprises a polyion gel and a dye, the dye being filled in the polyion gel;

the dye can change color when the concentration of the parameter to be measured is different.

Images