CN212301568U - Magnetic bead oscillation position detection device - Google Patents
Magnetic bead oscillation position detection device Download PDFInfo
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- CN212301568U CN212301568U CN202021791516.XU CN202021791516U CN212301568U CN 212301568 U CN212301568 U CN 212301568U CN 202021791516 U CN202021791516 U CN 202021791516U CN 212301568 U CN212301568 U CN 212301568U
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Abstract
The utility model discloses a magnetic bead oscillation position detection device, which comprises a processor, a magnetic bead detection module, a frequency division circuit and a differential amplification circuit; the output end of the magnetic bead detection module is connected with the input end of the frequency division circuit, the output end of the frequency division circuit is connected with the input end of the differential amplification circuit, and the output end of the differential amplification circuit is connected with the input end of the processor. The utility model discloses a design principle of two inductances adopts coil inductance parallel layout on PCB, and the mode of the hollow winding when having replaced single inductance effectively solves inductance uniformity problem, if when having the multichannel, has eliminated the difference that detects sensing element, the processing of being convenient for simultaneously. The design of double inductors is more favorable for the extraction of signals in the signal processing and extracting process, common mode interference signals can be effectively eliminated after difference, and the signals are cleaner.
Description
Technical Field
The utility model relates to a signal processing technology field, in particular to magnetic bead oscillation position detection device.
Background
In the prior art, the traditional blood coagulation analysis system mainly adopts a signal extraction circuit and a structure of a double magnetic circuit magnetic bead method. At present, the structural design mainly focuses on single inductors aiming at the detection signal extraction of a double magnetic circuit magnetic bead method, and the single inductors generally adopt a hollow winding mode, so that the inductance of each inductor is inconsistent, and the accuracy of a coagulation analysis system is inconsistent; in the single-inductance hollow winding structure, the inductance vibrates during working, so that the position of the magnetic beads changes, the extraction of position signals of the magnetic beads is influenced, and the analysis precision is reduced.
Disclosure of Invention
To the lower problem of single inductance extraction signal precision in the prior art, the utility model provides a magnetic bead oscillation position detection device arranges the signal acquisition inductance in oscillating circuit to thereby extract through extracting signal frequency characteristic or amplitude characteristic and realize oscillating magnetic bead position signal's extraction.
In order to achieve the above object, the present invention provides the following technical solutions:
the magnetic bead oscillation position detection device comprises a processor, a magnetic bead detection module, a frequency division circuit and a differential amplification circuit;
the output end of the magnetic bead detection module is connected with the input end of the frequency division circuit, the output end of the frequency division circuit is connected with the input end of the differential amplification circuit, and the output end of the differential amplification circuit is connected with the input end of the processor.
Preferably, the magnetic bead detection module comprises a first inductor L1 and a second inductor L2; the first inductor L1 and the second inductor L2 are arranged in parallel on the PCB, the first inductor L1 is connected to the output port a, and the second inductor L2 is connected to the output port C.
Preferably, the first inductor L1 and the second inductor L2 are both connected to the output port B.
Preferably, the first inductor L1 and the second inductor L2 are both coil inductors.
To sum up, owing to adopted above-mentioned technical scheme, compare with prior art, the utility model discloses following beneficial effect has at least:
the utility model discloses a design principle of two inductances adopts coil inductance parallel layout on PCB, and the mode of the hollow winding when having replaced single inductance effectively solves inductance uniformity problem, if when having the multichannel, has eliminated the difference that detects sensing element, the processing of being convenient for simultaneously. The design of double inductors is more favorable for the extraction of signals in the signal processing and extracting process, common mode interference signals can be effectively eliminated after difference, and the signals are cleaner.
Description of the drawings:
fig. 1 is a schematic view of a magnetic bead oscillation position detection apparatus according to an exemplary embodiment of the present invention.
Fig. 2 is a schematic structural diagram of a magnetic bead detection module according to an exemplary embodiment of the present invention.
Fig. 3 is a schematic diagram of an application of a magnetic bead detection module according to an exemplary embodiment of the present invention.
Fig. 4 is a schematic circuit diagram of a magnetic bead detection module according to an exemplary embodiment of the present invention.
Fig. 5 is a schematic diagram of a differential amplifier circuit according to an exemplary embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to examples and specific embodiments. However, it should not be understood that the scope of the above-mentioned subject matter is limited to the following embodiments, and all the technologies realized based on the present invention are within the scope of the present invention.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships illustrated in the drawings, and are used merely for convenience of description and for simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
As shown in fig. 1, the present invention provides a magnetic bead oscillation position detection apparatus, which specifically includes a magnetic bead detection module, a frequency division circuit, a differential amplification circuit and a processor; the output end of the magnetic bead detection module is connected with the input end of the frequency division circuit, the output end of the frequency division circuit is connected with the input end of the differential amplification circuit, and the output end of the differential amplification circuit is connected with the input end of the processor.
In this embodiment, the magnetic bead detection module adopts a dual-inductor structure, and is configured to collect an oscillation position signal of a magnetic bead and convert the oscillation position signal into an electrical signal;
the frequency division circuit is used for carrying out frequency division processing on the signal frequency of the electric signal so as to extract pulse signals respectively output by the double inductors; the frequency dividing circuit is an existing frequency dividing single circuit, and therefore, the details are not repeated herein.
And the differential amplifying circuit is used for amplifying the pulse signals respectively output by the double inductors so as to eliminate common-mode interference signals, so that the processor can identify according to the amplified signals.
In this embodiment, due to the influence of the magnetic bead oscillation position, the inductance of the two inductors in the magnetic bead detection module may be different, so that the oscillation conditions in the oscillation circuit are different, that is, the pulse signals output by the two inductors may be different, the amplitude of the pulse signal and the position of the magnetic bead have a unique correspondence, and the processor may detect the position of the magnetic bead oscillation according to the unique correspondence.
In this embodiment, as shown in fig. 2, the magnetic bead detection module includes a first inductor L1 and a second inductor L2, and the first inductor L1 and the second inductor L2 are both coil inductors, so that the problem of inductance consistency is solved, and the accuracy of signal extraction is improved; meanwhile, the difference of the detection sensing elements is eliminated, and the processing is convenient. The first inductor L1 and the second inductor L2 are arranged in parallel on the PCB board, and the first inductor L1 and the second inductor L2 have a common output port B. In this embodiment, in order to facilitate the output of the signals of the first inductor L1 and the second inductor L2, the first inductor L1 is further connected to the output port a, and the second inductor L2 is further connected to the output port C.
Fig. 3 is a schematic diagram illustrating an application of a magnetic bead detection module. The test cup containing the magnetic beads is placed between the first inductor L1 and the second inductor L2 of the magnetic bead detection module.
When the magnetic beads move in the test cup, due to the influence of the oscillation amplitude and position of the magnetic beads, the inductance of the first inductor L1 and the inductance of the second inductor L2 are different, so that the frequency and the amplitude of a first electric signal and a first pulse signal output by the first inductor L1 and the frequency and the amplitude of a second electric signal and a second pulse signal output by the second inductor L2 are different, the amplitude of the pulse signals and the positions of the magnetic beads have unique corresponding relations, the processor can detect the oscillation positions of the magnetic beads according to the unique corresponding relations, and the oscillation positions of the magnetic beads are displayed on output equipment, wherein the output equipment is thermal printer and LCD display equipment.
In this embodiment, as shown in fig. 4, the schematic circuit diagram of the magnetic bead detection module includes a processor U1, a resistor and a capacitor, and the specific circuit connections are as follows:
one end of a first resistor R1 is connected with a power supply, the other end of the first resistor R1 is connected with one end of a first capacitor C1, an emitter of a first triode Q1, an emitter of a second triode Q2 and one end of a second capacitor C2 respectively, the other end of the first capacitor C1 is grounded, a collector of the first triode Q1 is connected with the 3 rd interface of a connector P1, a base of the first triode Q1 is connected with the L2 SW1 interface (4Y port of the processor U1) of the processor U1, a collector of the second triode Q2 is connected with the 2 nd interface of the connector P1, and a base of the second triode Q2 is connected with the L1 SW1 interface (1Y port of the processor U1) of the processor U1; the other end of the second capacitor C2 is connected to the 1 st interface of the connector P1, one end of the third capacitor C3 and one end of the fourth capacitor C4, respectively, the other end of the third capacitor C3 is connected to one end of the second resistor R2, and the other end of the second resistor R2 is connected to the 3Y port of the processor U1; the other end of the fourth capacitor C4 is connected with one end of a third resistor R3, the other end of the third resistor R3 is connected with one end of a fourth resistor R4 and the 2A port of the processor U1, and the other end of the fourth resistor R4 is connected with the 2Y port and the 3A port of the processor U1; the 1A port of the processor U1 outputs a PWM2 OUT11 signal, and the GND port of the processor U1 is grounded; a VCC port of the processor U1 is respectively connected with one end of a fifth capacitor C5 and a power supply end, and the other end of the fifth capacitor C5 is grounded; the 6A port of the processor U1 outputs a PWM1 OUT1 signal, the 5A and 4A ports of the processor U1 output a PWM2 OUT1 signal, the 6Y port (INPUT L1-1) of the processor U1 outputs a first oscillation signal of a first inductor L1 to the frequency dividing circuit, and the 5Y port (INPUT L2-1) of the processor U1 outputs a second oscillation signal of a second inductor L2 to the frequency dividing circuit.
In this embodiment, as shown in fig. 5, a schematic circuit diagram of a differential amplifier circuit is shown, and the differential amplifier circuit includes an amplifier U2, an amplifier U3, an amplifier U4, a resistor, and a capacitor, and the specific circuit connections are as follows:
one end of a fifth resistor R5 is connected with a power supply, the other end of the fifth resistor R5 is respectively connected with one end of a sixth capacitor C6, a positive power supply end of an amplifier U2, a positive power supply end of the amplifier U3 and a positive power supply end of an amplifier U4, and the other end of the sixth capacitor C6 is grounded; one end of a sixth resistor R6 receives the first oscillation signal processed by the frequency dividing circuit, the other end of the sixth resistor R6 is respectively connected with one end of a seventh resistor R7 and one end of a seventh capacitor C7, and the other end of the seventh resistor R7 is respectively connected with one end of an eighth resistor R8 and the inverting input end of an amplifier U2; one end of a ninth resistor R9 receives the second oscillation signal processed by the frequency dividing circuit, the other end of the ninth resistor R9 is connected to one end of a tenth resistor R10 and one end of an eighth capacitor C8, the other end of the tenth resistor R10 is connected to the non-inverting input terminal of the amplifier U2 and one end of a twelfth resistor R12, the other end of the twelfth resistor R12 is connected to one end of an eleventh resistor R11, and the other end of the eleventh resistor R11 is connected to the other end of the seventh capacitor C7 and the other end of the eighth capacitor C8, and then grounded; the other end of the eleventh resistor R11 is also connected with one end of a ninth capacitor C9;
the output end of the amplifier U2 is connected to the other end of the eighth resistor R8 and one end of the fourteenth resistor R14, the other end of the fourteenth resistor R14 is connected to one end of the fifteenth resistor R15, one end of the sixteenth resistor R16 and one end of the tenth capacitor C10, the other end of the sixteenth resistor R16 is connected to one end of the eleventh capacitor C11 and the inverting input end of the amplifier U3, the other end of the tenth capacitor C10 is connected to the non-inverting input end of the amplifier U3, and the other end of the tenth capacitor C10 is also grounded; the output end of the amplifier U3 is respectively connected with the other end of an eleventh capacitor C11 and one end of a seventeenth resistor R17, the other end of the seventeenth resistor R17 is respectively connected with the other end of a fifteenth resistor R15, one end of an eighteenth resistor R18 and one end of a twelfth capacitor C12, and the other end of the twelfth capacitor C12 is grounded;
the other end of the eighteenth resistor R18 is respectively connected with one end of a nineteenth resistor R19, one end of a thirteenth capacitor C13 and the inverting input end of the amplifier U4; the other end of the nineteenth resistor R19 is respectively connected with one end of a twentieth resistor R20 and one end of a twenty-first resistor R21 (variable resistor), and the other end of the twentieth resistor R20 and the other end of the twenty-first resistor R21 (variable resistor) are connected in parallel and then connected with the output end of the amplifier U4; the other end of the thirteenth capacitor C13 is connected to the non-inverting input terminal of the amplifier U4 and one end of the twenty-second resistor R22, respectively, and the other end of the twenty-second resistor R22 is grounded;
one end of the thirteenth resistor R13 is connected to a power supply terminal (VEE), and the other end of the thirteenth resistor R13 is connected to the other end of the ninth capacitor C9, the negative power supply terminal of the amplifier U2, the negative power supply terminal of the amplifier U3, and the negative power supply terminal of the amplifier U4, respectively.
It will be understood by those skilled in the art that the foregoing embodiments are specific examples of the invention, and that various changes in form and details may be made therein without departing from the spirit and scope of the invention in its practical application.
Claims (6)
1. The magnetic bead oscillation position detection device comprises a processor and is characterized by comprising a magnetic bead detection module, a frequency division circuit and a differential amplification circuit;
the output end of the magnetic bead detection module is connected with the input end of the frequency division circuit, the output end of the frequency division circuit is connected with the input end of the differential amplification circuit, and the output end of the differential amplification circuit is connected with the input end of the processor.
2. The apparatus of claim 1, wherein the magnetic bead detection module comprises a first inductor L1 and a second inductor L2; the first inductor L1 and the second inductor L2 are arranged in parallel on the PCB, the first inductor L1 is connected to the output port a, and the second inductor L2 is connected to the output port C.
3. The apparatus of claim 2, wherein the first inductor L1 and the second inductor L2 are both connected to the output port B.
4. The apparatus of claim 2, wherein the first inductor L1 and the second inductor L2 are both coil inductors.
5. The device for detecting the oscillating position of a magnetic bead of claim 1, wherein the magnetic bead detection module comprises a processor U1, a connector, a resistor, and a capacitor:
one end of the first resistor is connected with a power supply, the other end of the first resistor is respectively connected with one end of the first capacitor, an emitter of the first triode, an emitter of the second triode and one end of the second capacitor, the other end of the first capacitor is grounded, a collector of the first triode is connected with a No. 3 interface of the connector, a base of the first triode is connected with an L2 SW1 interface of the processor U1, a collector of the second triode is connected with a No. 2 interface of the connector, and a base of the second triode is connected with an L1 SW1 interface of the processor U1; the other end of the second capacitor is connected with the 1 st interface of the connector, one end of the third capacitor and one end of the fourth capacitor respectively, the other end of the third capacitor is connected with one end of the second resistor, and the other end of the second resistor is connected with the 3Y port of the processor U1; the other end of the fourth capacitor is connected with one end of the third resistor, the other end of the third resistor is respectively connected with one end of the fourth resistor and the 2A port of the processor U1, and the other end of the fourth resistor is respectively connected with the 2Y port and the 3A port of the processor U1; the VCC port of the processor U1 is connected to one end of the fifth capacitor and the power supply terminal, respectively, and the other end of the fifth capacitor is grounded.
6. The apparatus of claim 1, wherein the differential amplifier circuit comprises an amplifier U2, an amplifier U3, an amplifier U4, a resistor, and a capacitor:
one end of the fifth resistor is connected with the power supply, the other end of the fifth resistor is respectively connected with one end of the sixth capacitor, the positive power supply end of the amplifier U2, the positive power supply end of the amplifier U3 and the positive power supply end of the amplifier U4, and the other end of the sixth capacitor is grounded; one end of a sixth resistor is connected with an INPUT L1-1 port, the other end of the sixth resistor is respectively connected with one end of a seventh resistor and one end of a seventh capacitor, and the other end of the seventh resistor is respectively connected with one end of an eighth resistor and the inverting INPUT end of an amplifier U2; one end of a ninth resistor is connected with an INPUT L2-1 port, the other end of the ninth resistor is respectively connected with one end of a tenth resistor and one end of an eighth capacitor, the other end of the tenth resistor is respectively connected with the non-inverting INPUT end of an amplifier U2 and one end of a twelfth resistor, the other end of the twelfth resistor is connected with one end of an eleventh resistor, and the other end of the eleventh resistor is respectively connected with the other end of a seventh capacitor and the other end of the eighth capacitor and then grounded; the other end of the eleventh resistor is also connected with one end of the ninth capacitor;
the output end of the amplifier U2 is connected with the other end of the eighth resistor and one end of the fourteenth resistor respectively, the other end of the fourteenth resistor is connected with one end of the fifteenth resistor, one end of the sixteenth resistor and one end of the tenth capacitor respectively, the other end of the sixteenth resistor is connected with one end of the eleventh capacitor and the inverting input end of the amplifier U3 respectively, the other end of the tenth capacitor is connected with the non-inverting input end of the amplifier U3, and the other end of the tenth capacitor is grounded; the output end of the amplifier U3 is respectively connected with the other end of the eleventh capacitor and one end of a seventeenth resistor, the other end of the seventeenth resistor is respectively connected with the other end of the fifteenth resistor, one end of an eighteenth resistor and one end of a twelfth capacitor, and the other end of the twelfth capacitor is grounded;
the other end of the eighteenth resistor is connected with one end of the nineteenth resistor, one end of the thirteenth capacitor and the inverting input end of the amplifier U4 respectively; the other end of the nineteenth resistor is connected with one end of the twentieth resistor and one end of the twenty-first resistor respectively, and the other end of the twentieth resistor and the other end of the twenty-first resistor are connected with the output end of the amplifier U4 after being connected in parallel; the other end of the thirteenth capacitor is respectively connected with the non-inverting input end of the amplifier U4 and one end of the twenty-second resistor, and the other end of the twenty-second resistor is grounded;
one end of the thirteenth resistor is connected with the power supply terminal, and the other end of the thirteenth resistor is connected with the other end of the ninth capacitor, the negative power supply terminal of the amplifier U2, the negative power supply terminal of the amplifier U3 and the negative power supply terminal of the amplifier U4 respectively.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202021791516.XU CN212301568U (en) | 2020-08-25 | 2020-08-25 | Magnetic bead oscillation position detection device |
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| CN202021791516.XU CN212301568U (en) | 2020-08-25 | 2020-08-25 | Magnetic bead oscillation position detection device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111912972A (en) * | 2020-08-25 | 2020-11-10 | 重庆南方数控设备股份有限公司 | Magnetic bead oscillation position detection system |
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- 2020-08-25 CN CN202021791516.XU patent/CN212301568U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111912972A (en) * | 2020-08-25 | 2020-11-10 | 重庆南方数控设备股份有限公司 | Magnetic bead oscillation position detection system |
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Granted publication date: 20210105 Termination date: 20210825 |