CN212270104U

CN212270104U - Sampling tube for collecting viruses or bacteria in expired air

Info

Publication number: CN212270104U
Application number: CN202020267916.4U
Authority: CN
Inventors: 陈立华; 丁萍; 陈文婷; 刘强; 谢文锋; 王帅
Original assignee: Changsha Yiyi Bioengineering Co ltd
Current assignee: Changsha Yiyi Bioengineering Co ltd
Priority date: 2020-03-06
Filing date: 2020-03-06
Publication date: 2021-01-01
Anticipated expiration: 2030-03-06

Abstract

The utility model relates to a sampling pipe of virus or bacterium in gathering expiration, gather liquid, inlet port, exhaust hole including blow gun, intake pipe, stock solution bottle, sample, the blow gun is linked together with the intake pipe, the lower extreme of intake pipe links to each other with the stock solution bottle, the sample is gathered liquid in the stock solution bottle, the lower extreme of intake pipe passes in the inlet port on stock solution bottle upper portion stretches into sample and gathers liquid, the upper portion of stock solution bottle still is equipped with the exhaust hole. The utility model discloses novel structure, easy operation is convenient, can improve the accuracy that detects moreover.

Description

Sampling tube for collecting viruses or bacteria in expired air

Technical Field

The utility model relates to a virus or bacterium collection system's technical field, concretely relates to sampling pipe of virus or bacterium in gathering expiration.

Background

The main transmission route of the virus or bacterial pneumonia is through respiratory droplets and contact transmission, when a human body is infected by the virus, the virus finally reaches alveoli through the respiratory tract of the human body, the content of the virus is different at different stages, the virus receptor expression ratio of the alveolar epithelial cells is the highest, and the ratio of airway epithelial cells, fibroblasts and the like is extremely low, so that the virus content of a lower respiratory tract is obviously higher than that of an upper respiratory tract.

At present, most nasopharyngeal swab samples are adopted, and due to the complexity and the specialty of sampling, viruses in nasopharyngeal cells are fewer or extremely low, so that the nasopharyngeal cells cannot be detected, and the nucleic acid detection of the nasopharyngeal swab (upper respiratory tract) samples is 'false negative'. In addition, in the nasopharynx swab sampling and detecting process, medical personnel need to sample the throat stimulation of the patient, and the operation risk of sampling and exposing of the medical personnel exists.

SUMMERY OF THE UTILITY MODEL

The utility model provides a technical problem lie in overcoming prior art's defect, provide a sampling pipe of virus or bacterium in gathering the expiration.

The utility model discloses a following technical scheme realizes:

the utility model provides a sampling pipe of virus or bacterium in gathering expiration, includes blowing nozzle, intake pipe, stock solution bottle, sample collection liquid, inlet port, exhaust hole, the blowing nozzle is linked together with the intake pipe, the lower extreme of intake pipe links to each other with the stock solution bottle, the sample collection liquid is equipped with in the stock solution bottle, the lower extreme of intake pipe passes in the inlet port on stock solution bottle upper portion stretches into sample collection liquid, the upper portion of stock solution bottle still is equipped with the exhaust hole.

Further, the liquid storage bottle comprises a top conical hollow body, a cylindrical hollow body and a bottom conical hollow body, an air inlet hole is formed in the center of the top conical hollow body, an exhaust hole is formed in the side face of the top conical hollow body, the lower end of the top conical hollow body is connected with the upper end of the cylindrical hollow body, the cylindrical hollow body is a section of cylindrical hollow body with two ends open, the lower end of the cylindrical hollow body is connected with the upper end of the bottom conical hollow body, the bottom conical hollow body is a reversely-mounted conical hollow body with the large upper end and the small lower end, a liquid drainage hole is formed in the bottom of the bottom conical hollow body, and the liquid drainage hole is connected with a liquid.

Further, go out the liquid device and include drain pipe, head, the upper end of drain pipe links to each other through the mode that splices, threaded connection or interference fit connects with the outage, the head is installed to the lower extreme of drain pipe.

Furthermore, the exhaust hole is connected with the lower end of the exhaust pipe, and the upper end of the exhaust pipe is provided with a liquid check valve.

Furthermore, the exhaust pipe is a plastic hose, and a first elastic clamp is mounted on the exhaust pipe.

Further, the liquid storage bottle comprises a bottle body and a bottle cap, a bottle opening is formed in the top of the bottle body, the bottle cap is installed on the bottle opening, and an air inlet hole, an air exhaust hole and a sampling needle hole are formed in the bottle cap.

Furthermore, the left end of the blowing nozzle is provided with an air blowing opening, the right end of the blowing nozzle is provided with an air outlet, and the air outlet is connected with an air inlet pipe.

Furthermore, a second elastic clamp is installed on the air inlet pipe.

Furthermore, the air inlet pipe is a plastic hose, and the air inlet pipe is 7-shaped.

Compared with the prior art, the utility model discloses following beneficial effect has:

the utility model relates to a sampling pipe of virus or bacterium can hang on the infusion support in the collection expiration, and the patient can be taken the semi-reclining position or sit the position, and handheld sampling pipe middle section is opened a mouthful and is contained the blow gun and blow, and the gas of patient's exhalation gets into sample collection liquid through the inlet port, sample collection liquid adsorbs and the enrichment to virus or bacterium in droplet and the exhaled air. After the collection is finished, the liquid outlet device or the injector is inserted into the liquid storage bottle to take out the specimen collection liquid, and then the specimen collection liquid is sent to a laboratory for inspection.

The main transmission route of the virus or bacterial pneumonia is through respiratory droplets and contact transmission, when a human body is infected by the virus, the virus finally reaches alveoli through the respiratory tract of the human body, the content of the virus is different at different stages, the virus receptor expression ratio of the alveolar epithelial cells is the highest, and the ratio of airway epithelial cells, fibroblasts and the like is extremely low, so that the virus content of a lower respiratory tract is obviously higher than that of an upper respiratory tract. At present, most nasopharyngeal swabs are adopted for sampling, and due to the complexity and the specialty of sampling, viruses in nasopharyngeal cells are fewer or extremely low, so that the viruses cannot be detected. The utility model discloses fully consider as above factor, improve the relevance ratio through the expiration (exhaling the air flue down) of gathering the patient, avoided nasopharyngeal swab (upper respiratory tract) sample nucleic acid detection's "false negative".

In addition, at nasopharynx swab sampling test process, medical personnel need sample patient's throat stimulation, this operating risk that just has medical personnel's sampling to expose, and the utility model discloses an adopt patient's initiative to exhale and sample by oneself, avoided the operating risk that medical personnel's sampling exposes, also alleviated the current situation that medical personnel's staff is not enough, also avoided children unwilling to cooperate the condition of nasopharynx swab sampling.

The utility model discloses be fit for a large amount of crowds general investigation, medical science isolation personnel are at and take a sample by oneself. The utility model discloses novel structure, easy operation can effectively avoid the "false negative" that detects, detects more accurately. In addition, the utility model discloses can carry out disposable sampling, open promptly and use. The utility model discloses also can be applied to the collection of other viruses or bacteria.

Drawings

Fig. 1 is a schematic structural diagram of embodiment 1 of the present invention.

Fig. 2 is a schematic structural diagram of embodiment 2 of the present invention.

In the attached drawing, 1, a blowing nozzle, 2, an air inlet pipe, 3, a liquid storage bottle, 4, a top conical hollow body, 5, a cylindrical hollow body, 6, a bottom conical hollow body, 7, an air inlet hole, 8, an exhaust hole, 9, an exhaust pipe, 10, a liquid stop valve, 11, a second elastic clamp, 12, a first elastic clamp, 13, a liquid discharge hole, 14, a liquid outlet pipe, 15, a sealing head, 16, a sampling needle hole, 17, a bottle body, 18, a bottle cover, 19, a specimen collection liquid, 20, a gas blowing port and 21, a gas outlet are arranged.

Detailed Description

The present invention will be further described with reference to the following embodiments. Wherein the showings are for the purpose of illustration only and are shown by way of illustration only and not in actual form, and are not to be construed as limiting the present patent; for a better understanding of the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.

Example 1

As shown in fig. 1, a sampling tube for collecting viruses or bacteria in breath comprises a blowing nozzle 1, an air inlet pipe 2, a liquid storage bottle 3, a specimen collection liquid 19, a liquid outlet device, an air inlet hole 7, an air outlet hole 8, an exhaust pipe 9, a liquid stop valve 10, a first elastic clamp 12, a second elastic clamp 11, a liquid outlet hole 13, a liquid outlet pipe 14 and a sealing head 15.

The blowing nozzle 1 is made of plastic, and the blowing nozzle 1 can be designed into a hollow cylinder shape, a round cup shape, a conical shape or other shapes. The left end of the blowing nozzle 1 is provided with an air blowing port 20, the right end of the blowing nozzle 1 is provided with an air outlet 21, and the air outlet 21 is connected with the air inlet pipe 2. The air inlet pipe 2 is a hollow plastic hose, and the shape of the air inlet pipe 2 is 7-shaped. The air outlet 21 is connected with the upper end of the air inlet pipe 2 through sealing and gluing by a strong glue, or connected in a plug-in interference connection and injection molding integral manufacturing mode. Preferably, the air inlet pipe 2 is provided with a second elastic clamp 11 which can be clamped or opened, and the second elastic clamp 11 is a plastic pipe clamp used by a nurse or a small iron clamp or a wood clamp existing in the market.

The lower end of the air inlet pipe 2 is connected with a liquid storage bottle 3, and a specimen collection liquid 19 is arranged in the liquid storage bottle 3. The liquid storage bottle 3 is a hollow bottle body 17, a box-shaped or tubular structure and is made of plastics. Preferably, the liquid storage bottle 3 is integrally formed by injection molding or die pressing of a top conical hollow body 4, a cylindrical hollow body 5 and a bottom conical hollow body 6. The top conical hollow body 4 is a hollow conical structure with a small upper end and a large lower end, and an air inlet 7 is arranged in the center of the top conical hollow body 4. The air inlet hole 7 is circular and is matched with the lower end of the air inlet pipe 2, and the lower end of the air inlet pipe 2 penetrates through the air inlet hole 7 and extends into the specimen collection liquid 19.

The lower end of the top conical hollow body 4 is connected with the upper end of the cylindrical hollow body 5, the cylindrical hollow body 5 is a section of cylindrical hollow body with two open ends, and the lower end of the cylindrical hollow body 5 is connected with the upper end of the bottom conical hollow body 6. The bottom conical hollow body 6 is an inverted conical hollow body with a large upper end and a small lower end, a liquid discharge hole 13 is formed in the bottom of the bottom conical hollow body 6, and the liquid discharge hole 13 is connected with a liquid discharge device.

The liquid outlet device comprises a liquid outlet pipe 14 and a sealing head 15, the upper end of the liquid outlet pipe 14 is connected with the liquid outlet hole 13 in a gluing mode, a threaded connection mode or an interference fit connection mode, and the sealing head 15 is installed at the lower end of the liquid outlet pipe 14. Preferably, drain pipe 14 is circular hollow plastic pipe, the lower extreme of drain pipe 14 is equipped with the external screw thread, head 15 is upper end opening lower extreme confined hollow circular cap shape structure, the inside of head 15 is equipped with the internal thread with the external screw thread looks adaptation of drain pipe 14 lower extreme, the lower extreme at drain pipe 14 is installed through the mode that the screw thread closes soon to head 15.

In addition, the side at the top of top toper hollow body 4 still is equipped with exhaust hole 8, exhaust hole 8 links to each other through the mode that bonds, threaded connection or interference fit connect with the lower extreme of blast pipe 9, liquid stop valve 10 is installed to the upper end of blast pipe 9, liquid stop valve 10 is the current product in market. The blast pipe 9 is plastic hose, install first elastic clamp 12 on the blast pipe 9, first elastic clamp 12 is the same with second elastic clamp 11, is the plastic pipe clip that the nurse used, or current little iron clip or the wood clip on the market.

The utility model discloses be fit for a large amount of crowds general investigation, medical science isolation personnel are at and take a sample by oneself. The utility model discloses novel structure, easy operation can effectively avoid the "false negative" that detects, detects more accurately. In addition, the utility model discloses can carry out disposable sampling, open promptly and use. The utility model discloses also can be applied to the collection of other viruses or bacteria. The utility model provides a sample collection liquid preferentially adopts the virus transportation culture medium (VTM) that World Health Organization (WHO) and national influenza center recommend to use, of course, also can adopt the culture medium solution that contains active carbon or other high molecular polymer that have adsorption performance, is used for adsorbing and enrichment virus or bacterium.

Example 2

As shown in fig. 2, a sampling tube for collecting viruses or bacteria in breath comprises a mouthpiece 1, an air inlet tube 2, a liquid storage bottle 3, a specimen collection liquid 19, an air inlet hole 7, an air outlet hole 8, and a sampling needle hole 16.

The blowing nozzle 1 is made of plastic, and the blowing nozzle 1 is in a hollow cylinder shape with an opening at the left end and is provided with a smooth edge. The opening of the left end of the blowing nozzle 1 is an air blowing opening 20, the right end of the blowing nozzle 1 is provided with a circular air outlet 21 matched with the air inlet pipe 2, and the air outlet 21 is connected with the upper end of the air inlet pipe 2 in a sealing and bonding mode through super glue. The air inlet pipe 2 is a hollow round plastic hose, and the air inlet pipe 2 is bent in a shape like a Chinese character '7'. Preferably, the air inlet pipe 2 is provided with a second elastic clamp 11 or other closing devices which can be clamped or opened, and the second elastic clamp 11 is a plastic pipe clamp used by nurses or a small iron clamp or a wooden clamp which is available on the market.

The lower end of the air inlet pipe 2 is connected with a liquid storage bottle 3, the liquid storage bottle 3 is composed of a bottle body 17 and a bottle cap 18, the hollow bottle body 17 is a hollow bottle body 17 with an opening at the upper end and a closed lower end, and a specimen collection liquid 19 is filled in the liquid storage bottle 3. The liquid storage bottle 3 is a plastic bottle or a glass bottle, a round bottle opening is formed in the upper end of the liquid storage bottle 3, and external threads are formed in the outer portion of the bottle opening. The bottle is characterized in that a bottle cap 18 is installed on the bottle mouth, the bottle cap 18 is a circular cap, an internal thread matched with the external thread on the outside of the bottle mouth is arranged on the inner side of the bottle cap 18, and the bottle cap 18 is fixed on the bottle mouth in a threaded screwing mode.

The bottle cap 18 is provided with an air inlet 7, an air outlet 8 and a sampling pinhole 16, and is made of plastics. The air inlet hole 7 is arranged at the center of the bottle cap 18, the air inlet hole 7 is preferably circular, the air inlet hole 7 is matched with the lower end of the air inlet pipe 2, and the lower end of the air inlet pipe 2 penetrates through the air inlet hole 7 to extend into the specimen collection liquid 19. The exhaust hole 8 and the sampling pinhole 16 are arranged at the left side and the right side of the air inlet hole 7, the exhaust hole 8 is a through hole with a circular shape or other shapes, a dustproof cap with air holes can be installed on the exhaust hole 8, the dustproof cap can also not be installed, and the sampling pinhole 16 is used for drawing a specimen collection liquid 19 by a liquid drawing tool such as an injector.

The above description is only the preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments. It should be noted that the plastic referred to in the present invention is the plastic of medical grade and hygiene grade, and a person skilled in the art can modify and decorate the liquid storage bottle or the liquid outlet device without departing from the principles of the present invention, such as changing the structure of the liquid storage bottle or the liquid outlet device, changing the materials used by each component, and the protection scope of the present invention should be considered. All the components not specified in the present embodiment can be realized by the prior art.

Claims

1. A sampling tube for collecting viruses or bacteria in exhaled breath, comprising: the specimen collecting device comprises a blowing nozzle, an air inlet pipe, a liquid storage bottle, a specimen collecting liquid, an air inlet hole and an exhaust hole, wherein the blowing nozzle is communicated with the air inlet pipe, the lower end of the air inlet pipe is connected with the liquid storage bottle, the specimen collecting liquid is arranged in the liquid storage bottle, the lower end of the air inlet pipe penetrates through the air inlet hole in the upper portion of the liquid storage bottle and extends into the specimen collecting liquid, and the exhaust hole is further formed in the upper portion of the liquid storage bottle.

2. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 1, wherein: the liquid storage bottle comprises a top conical hollow body, a cylindrical hollow body and a bottom conical hollow body, wherein an air inlet hole is formed in the center of the top conical hollow body, an exhaust hole is formed in the side face of the top conical hollow body, the lower end of the top conical hollow body is connected with the upper end of the cylindrical hollow body, the cylindrical hollow body is a section of cylindrical hollow body with two open ends, the lower end of the cylindrical hollow body is connected with the upper end of the bottom conical hollow body, the bottom conical hollow body is a inverted conical hollow body with a large upper end and a small lower end, a liquid drainage hole is formed in the bottom of the bottom conical hollow body, and the liquid drainage hole is connected with a.

3. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 2, wherein: the liquid outlet device comprises a liquid outlet pipe and a sealing head, the upper end of the liquid outlet pipe is connected with the liquid outlet hole in a gluing, threaded connection or interference fit manner, and the sealing head is installed at the lower end of the liquid outlet pipe.

4. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 2, wherein: the exhaust hole is connected with the lower end of the exhaust pipe, and the upper end of the exhaust pipe is provided with a liquid stop valve.

5. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 4, wherein: the exhaust pipe is a plastic hose, and a first elastic clamp is installed on the exhaust pipe.

6. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 1, wherein: the liquid storage bottle comprises a bottle body and a bottle cap, wherein a bottle opening is formed in the top of the bottle body, the bottle cap is installed on the bottle opening, and an air inlet hole, an air exhaust hole and a sampling needle hole are formed in the bottle cap.

7. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 1, wherein: the left end of the blowing nozzle is provided with an air blowing opening, the right end of the blowing nozzle is provided with an air outlet, and the air outlet is connected with an air inlet pipe.

8. The sampling tube for collecting viruses or bacteria in exhaled breath according to claim 7, wherein: and a second elastic clamp is arranged on the air inlet pipe.

9. A sampling tube for collecting viruses or bacteria in exhaled breath according to claim 8, wherein: the air inlet pipe is a plastic hose and is 7-shaped.