CN212228533U - Full-automatic semen processing device - Google Patents
Full-automatic semen processing device Download PDFInfo
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- CN212228533U CN212228533U CN202020697526.0U CN202020697526U CN212228533U CN 212228533 U CN212228533 U CN 212228533U CN 202020697526 U CN202020697526 U CN 202020697526U CN 212228533 U CN212228533 U CN 212228533U
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- semen
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- processing device
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Abstract
The utility model discloses a full-automatic semen processing device. It includes: a semen liquefaction cavity, wherein a semen taking cup placing table and a glass slide are arranged in the semen liquefaction cavity; a semen incubation cavity, wherein a push-pull test tube rack is arranged in the semen incubation cavity; the semen operation cavity is internally provided with a centrifugal machine, a first mechanical arm and a second mechanical arm, and the top of the first mechanical arm is provided with a pipette head; the lower part of the second mechanical arm is provided with a pipe clamp, and the upper part of the second mechanical arm is provided with a rotatable pipe cover gripper; and the control device includes: the centrifugal machine comprises a controller, a display panel, a temperature regulator, a humidity regulator, a carbon dioxide regulator, a temperature sensor, a humidity sensor and a carbon dioxide sensor, wherein the display panel, the temperature regulator, the humidity regulator, the carbon dioxide regulator, the temperature sensor, the humidity sensor and the carbon dioxide sensor are connected with the controller, and the centrifugal machine, the first mechanical arm and the second mechanical arm are all connected with the controller in a control mode. Compare with conventional laboratory processing semen, this full-automatic semen processing apparatus provides a portable clean space, and whole semen processing procedure need not manual operation, reduces the pollution risk, improves work efficiency.
Description
Technical Field
The utility model relates to a semen field of handling especially is about a full-automatic semen processing apparatus.
Background
Semen processing technology is a basic technology of assisted reproductive laboratories and sperm bank laboratories, and is generally performed by manual operations in a sterile environment.
At present, the requirement of the cleanliness grade of a semen treatment room is not lower than the class 2 standard of the medical place of Ministry of health, and semen treatment personnel need to be trained by auxiliary reproductive technology professionals. In remote areas of China, the construction and personnel allocation of semen treatment laboratories are not perfect, especially under extreme conditions of high temperature, high cold, high altitude and the like. In order to solve various problems in semen collection and semen processing and storage in remote areas or extreme environments, a device which can move to clean space and automatically complete semen processing is needed.
The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information constitutes prior art already known to a person skilled in the art.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a simple structure is reasonable full-automatic semen processing apparatus, it can accomplish to provide a portable clean space, and accomplishes semen processing procedure automatically, effectively improves germ cell storage guarantee scope.
In order to achieve the above object, the utility model provides a full-automatic semen processing device, include: the semen liquefaction cavity is internally provided with a semen taking cup placing table, a recovery box and a glass slide, and a placing groove is formed in the semen taking cup placing table; a semen incubation cavity, wherein a push-pull test tube rack is arranged in the semen incubation cavity; the semen operation cavity is internally provided with a centrifugal machine, a first mechanical arm and a second mechanical arm, the first mechanical arm is movably arranged at the tops of the semen liquefaction cavity and the semen operation cavity through a first slide rail and is a straw type mechanical arm, a plurality of straw heads are sequentially arranged in the straw type mechanical arm, and the straw head at the outermost end extends out of the straw head to absorb liquid; the second mechanical arm is movably arranged at the top of the semen operation cavity through a second slide rail and is a gripper type mechanical arm, a pipe clamp is arranged at the lower part of the second mechanical arm, and a pipe cover gripper and a pipe cover sleeve which can rotate are arranged at the upper part of the second mechanical arm; and the control device includes: the device comprises a controller, and a display panel, a temperature regulator, a humidity regulator, a carbon dioxide regulator, a temperature sensor, a humidity sensor and a carbon dioxide sensor which are connected with the controller, wherein the centrifugal machine, a first mechanical arm and a second mechanical arm are all in control connection with the controller, the outer sides of a semen liquefaction cavity, a semen operation cavity and a semen incubation cavity are formed by wrapping surrounding plates, sealing partition plates are arranged among the semen liquefaction cavity, the semen operation cavity and the semen incubation cavity, and are connected with an external carbon dioxide gas cylinder through a carbon dioxide connector; and the semen liquefaction cavity and the semen operation cavity are provided with automatic sampling doors on the sealing partition plates.
In a preferred embodiment, the centrifuge is a double tube centrifuge having a sample centrifuge tube well and a balancing centrifuge tube well, and a balancing centrifuge tube with a balancing liquid is placed in the balancing centrifuge tube well.
In a preferred embodiment, the table surface of the fine cup placing table is concave.
In a preferred embodiment, the tip of the pipette head is provided with a resilient tab by which the pipette head is snapped into the first mechanical arm.
In a preferred embodiment, an ultraviolet disinfection lamp is also arranged in the fully automatic semen processing device.
In a preferred embodiment, the bottom of the fully automatic semen processing device is provided with universal wheels.
In a preferred embodiment, the push-pull test tube rack is provided with multi-aperture test tube holes.
Compared with the prior art, according to the utility model discloses a full-automatic semen processing apparatus has following beneficial effect: this full-automatic semen processing apparatus can accomplish to provide a portable clean space, and accomplishes the semen processing procedure voluntarily, effectively improves germ cell storage guarantee scope. This full-automatic semen processing apparatus need not manual operation, reduces the pollution risk, can improve work efficiency.
Drawings
Fig. 1 is a schematic perspective view of a fully automatic semen processing device according to an embodiment of the present invention.
Fig. 2 is a schematic top view of a fully automatic semen processing device according to an embodiment of the present invention.
Fig. 3 is a schematic view of a first mechanical arm of a fully automatic semen processing device according to an embodiment of the present invention.
Fig. 4 is a schematic partial sectional structural view of a first mechanical arm of a fully automatic semen processing device according to an embodiment of the present invention.
Fig. 5 is a schematic diagram of a second mechanical arm of the fully automatic semen processing device according to an embodiment of the present invention.
Fig. 6 is a schematic top view of a second mechanical arm of the fully automatic semen processing device according to an embodiment of the present invention.
Detailed Description
The following detailed description of the present invention is provided in conjunction with the accompanying drawings, but it should be understood that the scope of the present invention is not limited by the following detailed description.
Throughout the specification and claims, unless explicitly stated otherwise, the word "comprise", or variations such as "comprises" or "comprising", will be understood to imply the inclusion of a stated element or component but not the exclusion of any other element or component.
As shown in fig. 1 and 2, the specific structure of the fully automatic semen processing device according to the preferred embodiment of the present invention includes: chamber and controlling means are hatched to seminal fluid liquefaction chamber, seminal fluid operation chamber, seminal fluid, and the outside in chamber is hatched to seminal fluid liquefaction chamber, seminal fluid operation chamber and seminal fluid forms through 1 parcel of bounding wall (1 local section of bounding wall in figure 1, so that observe its inner structure), has laid sealed partition each other to link to each other with outside carbon dioxide gas cylinder through carbon dioxide connector 10. The control device controls the temperature, humidity and gas of the semen liquefying cavity, the semen operating cavity and the semen incubation cavity, so that the use state of the semen liquefying cavity is kept at the default setting of 37 degrees, and the 6% carbon dioxide environment is adjustable and can be placed in a conventional environment for use, thereby providing an environment required by semen processing operation. Meanwhile, the fully-automatic semen processing device can automatically complete the semen separation and storage process after semen collection, and the semen processing process does not need manual operation.
Particularly, the side of semen liquefaction chamber has been seted up sample transmission window and consumptive material transmission window, and the sample transmission window is used for getting and puts the sample, and the consumptive material transmission window is used for getting and puts the consumptive material (straw head box, slide glass). The semen extracting cup placing table 2 and the glass slide 3 are arranged in the semen liquefying cavity, and a placing groove is formed in the semen extracting cup placing table 2 and used for placing the semen extracting cup 4. A recovery box is arranged beside the fine cup placing table 2 and is used for placing a straw head, waste liquid and the like after use. After semen is taken, the semen taking cup is placed in the placing groove of the semen taking cup placing table 2 of the semen liquefying cavity through the sample transfer window, and standing and liquefying are carried out for 30 minutes. And then moving the slide glass to the upper part through a first mechanical arm, sucking semen, dripping the semen onto the slide glass, conveying the slide glass out, and continuing to start the next procedure after the personnel observe the semen to meet the requirements.
In one embodiment, the semen collection cup placement platform 2 is slightly recessed to prevent the semen collection cup from pouring the semen flow down to the semen collection cup placement platform.
The semen incubation cavity is provided with different types of push-pull test tube racks 5 and is provided with a centrifugal tube transfer window. The push-pull test tube rack 5 is provided with test tube holes with different apertures and used for placing sample test tubes (centrifuge tubes or freezing storage tubes), and the push-pull test tube rack 5 enters the semen operation cavity through a centrifuge tube transmission window to perform related operations.
The semen operation cavity is internally provided with a centrifuge 6, a first mechanical arm 7 and a second mechanical arm 8, and the centrifuge 6 is used for carrying out centrifugal operation on the sample test tube. The first mechanical arm 7 is movably arranged at the tops of the semen liquefaction cavity and the semen operation cavity through a first sliding rail. As shown in fig. 3 and 4, the first robot arm 7 is a pipette-type robot arm, and a plurality of pipette tips 71 are sequentially disposed inside the first robot arm, and the pipette tip at the outermost end extends out to suck liquid, discharge liquid, and mix liquid. After the outermost straw head is used, the first mechanical arm can automatically replace the straw head under the control of the controller (the outermost straw head falls off, and the inner straw head moves forwards for standby). The second mechanical arm 8 is movably arranged at the top of the semen operation cavity through a second sliding rail. As shown in fig. 4 and 5, the second robot arm 8 is a gripper-type robot arm, and a tube clamp 81 is provided at a lower portion thereof to clamp a sample tube (centrifuge tube or vial) that can be opened and closed. The upper portion of second arm 8 is provided with tube cap tongs 82 and tube cap cover 83 that can rotate, and tube cap tongs 82 is used for grabbing and rotatory spiro union tube cap of opening this test tube of sample (centrifuging tube or cryopreserving pipe). The cap sleeve 83 is used to cover and rotate the cap of the sample tube (centrifuge tube or cryopreserving tube).
In one embodiment, the centrifuge 6 is a dual tube centrifuge, in which a sample centrifuge tube slot and a balancing centrifuge tube slot are arranged, and a balancing centrifuge tube with balancing liquid is arranged in the balancing centrifuge tube slot, so as to meet the operating principle of a single sample for semen processing and prevent semen confusion.
In one embodiment, the end of the pipette head 71 is provided with a resilient tab 72 by which the pipette head is snapped into the first robot arm 7; after the use, the suction pipe head at the outermost end is ejected, and the elastic piece is bounced off.
The control device includes: the device comprises a controller, a display panel 9, a temperature regulator, a humidity regulator, a carbon dioxide regulator, a temperature sensor, a humidity sensor and a carbon dioxide sensor, wherein the display panel 9, the temperature regulator, the humidity regulator, the carbon dioxide regulator, the temperature sensor, the humidity sensor, the carbon dioxide sensor, a centrifugal machine 6, a first mechanical arm 7 and a second mechanical arm 8 are all in control connection with the controller, and the display panel 9 is used for displaying temperature, humidity and carbon dioxide concentration alarm and selecting an operation program.
In one embodiment, an ultraviolet disinfection lamp is also arranged in the full-automatic semen processing device.
In one embodiment, the bottom of the fully automatic semen processing device is provided with a universal wheel 11, which facilitates the movement of the fully automatic semen processing device.
The operation procedure of the fully automatic semen processing device is as follows:
Liquefaction of semen: after the semen was placed in the liquefaction chamber and liquefied for 30 minutes, program 1 was initiated. The first mechanical arm 7 moves to the upper part of the liquefaction cavity and the semen taking cup; the first mechanical arm 7 descends until the pipette head enters the position below the liquid level of the semen; the straw head sucks 10ul of semen; the first mechanical arm 7 is lifted and restored to the original height; the first mechanical arm 7 moves above the slide; dripping semen to the glass slide by the suction pipe head; the slide is transferred out, and the first mechanical arm 7 automatically changes the pipette head.
Semen is processed by density gradient centrifugation: the semen culture cavity is communicated with a centrifuge tube to the semen operation cavity; the second mechanical arm 8 (a hand-grip mechanical arm) grasps the centrifugal tube cap and opens the centrifugal tube cap; the first mechanical arm 7 sucks the 1m density gradient centrifugate a, the centrifugate a is added into a centrifuge tube, and the first mechanical arm 7 automatically changes a pipette head; the first mechanical arm 7 absorbs the density gradient centrifugate b with the density of 1m, the centrifugate b is slowly added into a centrifugal tube along the wall of the centrifugal tube, and the first mechanical arm 7 automatically changes a pipette head; the first mechanical arm 7 moves to the upper part of the semen taking cup of the liquefaction cavity to absorb 1m of semen; the first mechanical arm 7 moves to the upper part of the centrifugal tube, and the semen is slowly dripped into the centrifugal tube; the second mechanical arm 8 covers the tube cover of the centrifugal tube; the second mechanical arm 8 descends to grasp the tube body of the centrifugal tube; the second mechanical arm 8 ascends and moves above the centrifugal machine, and descends to place the centrifugal pipe in the centrifugal machine; centrifuging for 20 minutes by using a centrifuge of 200 g;
the second mechanical arm 8 opens the tube cover of the centrifugal tube; the first mechanical arm 7 sucks the supernatant, the supernatant is discharged to a waste liquid tank, and the first mechanical arm 7 automatically changes the pipette head; 3ml of G-IVF liquid is absorbed by the first mechanical arm 7, added into the centrifugal tube precipitate, and pumped up and down to be uniformly mixed; the second mechanical arm 8 covers the tube cover of the centrifugal tube; centrifuging for 6 minutes by using a centrifuge with 300 g;
the second mechanical arm 8 opens the tube cover of the centrifugal tube; the first mechanical arm 7 sucks the supernatant, the supernatant is discharged to a waste liquid tank, and the first mechanical arm 7 automatically changes the pipette head; the first mechanical arm 7 sucks 1ml of G-IVF liquid, adds the liquid into a centrifugal tube precipitate, and sucks the liquid up and down to mix the liquid uniformly; the semen culture cavity is used for transferring out the cryopreservation tube, and the second mechanical arm 8 is used for opening the tube cover of the cryopreservation tube; the first mechanical arm 7 sucks the sperm mixed solution, the sperm mixed solution is added into the cryopreservation tube, and the pipette head is automatically replaced by the first mechanical arm 7;
the first mechanical arm 7 absorbs 1ml of sperm freezing protection solution and slowly adds the sperm freezing protection solution into a freezing tube drop by drop; covering a tube cover of the cryopreservation tube by using a second mechanical arm 8, and standing the cryopreservation tube for 10 minutes; and (5) transferring the frozen tube.
To sum up, this full-automatic semen processing apparatus can accomplish to provide a portable clean space, and accomplishes the semen processing procedure voluntarily, effectively improves germ cell storage guarantee scope. This full-automatic semen processing apparatus need not manual operation, reduces the pollution risk, can improve work efficiency.
The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. It is not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain certain principles of the invention and its practical application to enable one skilled in the art to make and use various exemplary embodiments of the invention and various alternatives and modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims and their equivalents.
Claims (7)
1. A fully automatic semen processing device, comprising:
the semen liquefaction cavity is internally provided with a semen taking cup placing table, a recovery box and a glass slide, and a placing groove is formed in the semen taking cup placing table;
a semen incubation cavity, wherein a push-pull test tube rack is arranged in the semen incubation cavity;
the semen operation cavity is internally provided with a centrifugal machine, a first mechanical arm and a second mechanical arm, the first mechanical arm is movably arranged at the tops of the semen liquefaction cavity and the semen operation cavity through a first slide rail and is a straw type mechanical arm, a plurality of straw heads are sequentially arranged in the straw type mechanical arm, and the straw head at the outermost end extends out of the straw head to absorb liquid; the second mechanical arm is movably arranged at the top of the semen operation cavity through a second slide rail and is a gripper type mechanical arm, a pipe clamp is arranged at the lower part of the second mechanical arm, and a pipe cover gripper and a pipe cover sleeve which can rotate are arranged at the upper part of the second mechanical arm; and
the control device includes: the device comprises a controller, and a display panel, a temperature regulator, a humidity regulator, a carbon dioxide regulator, a temperature sensor, a humidity sensor and a carbon dioxide sensor which are connected with the controller, wherein the centrifugal machine, a first mechanical arm and a second mechanical arm are all in control connection with the controller, the outer sides of a semen liquefaction cavity, a semen operation cavity and a semen incubation cavity are formed by wrapping surrounding plates, sealing partition plates are arranged among the semen liquefaction cavity, the semen operation cavity and the semen incubation cavity, and are connected with an external carbon dioxide gas cylinder through a carbon dioxide connector; and the semen liquefaction cavity and the semen operation cavity are provided with automatic sampling doors on the sealing partition plates.
2. The fully automated semen processing device of claim 1, wherein the centrifuge is a dual tube centrifuge having a sample centrifuge tube well and a balancing centrifuge tube well disposed therein, and wherein a balancing centrifuge tube with a balancing fluid is disposed in the balancing centrifuge tube well.
3. The fully automated semen processing device of claim 1, wherein the top of the semen collection cup holding platform is recessed.
4. The fully automatic semen processing device according to claim 1, wherein the tip of the pipette head is provided with an elastic piece by which the pipette head is snapped into the first mechanical arm.
5. The fully automatic semen processing device of claim 1 further comprising an ultraviolet disinfection lamp disposed therein.
6. The fully automatic semen processing device of claim 1 wherein a bottom portion of the fully automatic semen processing device is provided with universal wheels.
7. The fully automatic semen processing device according to claim 1, wherein the push-pull test tube rack is provided with a multi-aperture test tube hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020697526.0U CN212228533U (en) | 2020-04-30 | 2020-04-30 | Full-automatic semen processing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020697526.0U CN212228533U (en) | 2020-04-30 | 2020-04-30 | Full-automatic semen processing device |
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| Publication Number | Publication Date |
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| CN212228533U true CN212228533U (en) | 2020-12-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202020697526.0U Expired - Fee Related CN212228533U (en) | 2020-04-30 | 2020-04-30 | Full-automatic semen processing device |
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| CN (1) | CN212228533U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111366436A (en) * | 2020-04-30 | 2020-07-03 | 中国人民解放军总医院 | Full-automatic semen processing device |
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2020
- 2020-04-30 CN CN202020697526.0U patent/CN212228533U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111366436A (en) * | 2020-04-30 | 2020-07-03 | 中国人民解放军总医院 | Full-automatic semen processing device |
| CN111366436B (en) * | 2020-04-30 | 2024-06-25 | 中国人民解放军总医院 | Full-automatic semen processing device |
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Granted publication date: 20201225 |