CN212142185U - Automatic solution diluting system - Google Patents
Automatic solution diluting system Download PDFInfo
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- CN212142185U CN212142185U CN202020786954.0U CN202020786954U CN212142185U CN 212142185 U CN212142185 U CN 212142185U CN 202020786954 U CN202020786954 U CN 202020786954U CN 212142185 U CN212142185 U CN 212142185U
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Abstract
The utility model discloses an automatic solution diluting system, which comprises a first reagent container and a second reagent container, wherein the second reagent container is communicated with an inlet of a liquid-extracting pump through a conveying pipe, an outlet of the liquid-extracting pump is communicated with a liquid-distributing container through a liquid-discharging pipe, and the conveying pipe is provided with a first electromagnetic valve; the liquid preparation container is communicated with an inlet of the liquid extracting pump through a liquid extracting pipe, and a second electromagnetic valve is arranged on the liquid extracting pipe; the liquid discharge pipe is provided with a two-position three-way electromagnetic valve, a third interface of the two-position three-way electromagnetic valve is communicated with the liquid injection main pipe, each liquid injection branch pipe communicated with the liquid injection main pipe is communicated with one subpackaging container, and a third electromagnetic valve is arranged on each liquid injection branch pipe. The utility model discloses use an drawing liquid pump to realize the automatic interpolation of reagent, the automatic even and the automatic partial shipment of mixing reagent, simple structure, ingenious, with low costs, easy operation joins in marriage that the liquid is fast and the precision is high, not only can be used to the dilution of concentrate, can also be used to the mixture of different reagents and join in marriage liquid.
Description
Technical Field
The utility model relates to a preparation of mixed reagent especially relates to an automatic system of diluting of solution suitable for prepare mixed reagent.
Background
In the field of biochemical detection, a wide variety of mixed reagents, i.e., mixed reagents in which at least two reagents are mixed together, are commonly encountered. The traditional method for preparing the mixed reagent is manual preparation, namely, the solution A, the solution B, the solution C and the like are manually added into a solution preparation container according to a certain proportion, and the mixture is shaken or stirred to be uniformly mixed. However, with the rapid development of the in vitro diagnosis industry, the detection amount of the in vitro diagnosis device is also increasing, and the automatic in vitro diagnosis device is favored by the market. The in vitro diagnostic equipment usually needs a large amount of cleaning agents in operation, the cleaning agents usually dilute the concentrated solution according to a certain proportion to obtain or the mixed solution of more than two kinds of reagents, the traditional manual preparation efficiency is low and the proportioning precision is not high, and the working requirements of the automatic in vitro diagnostic equipment can not be met far away.
In order to solve the above problems, the liquid is often prepared by using a quantitative pump during detection, and purified water (or other diluents) and concentrated liquid are alternately added by using one quantitative pump or concentrated liquid is respectively added by using two quantitative pumps during liquid preparation. Compared with a manual liquid preparation method, the method improves the liquid preparation precision and efficiency to a certain extent, but the quantitative pump is expensive and has higher cost; when the liquid is prepared, the concentrated solution (such as BF washing liquid) is easy to crystallize to cause the blockage of the quantitative pump; meanwhile, the method does not need to uniformly mix purified water and concentrated solution to influence the cleaning effect.
Disclosure of Invention
The utility model aims to provide a join in marriage liquid fast, join in marriage automatic dilution system of solution that liquid precision is high.
In order to achieve the above purpose, the utility model adopts the following technical proposal:
the utility model discloses an automatic solution diluting system, including first reagent container and at least one second reagent container, every said second reagent container is linked together through the import of conveyer pipe and drawing liquid pump, the export of drawing liquid pump is linked together through fluid-discharge tube and liquid distribution container, be provided with first solenoid valve on the conveyer pipe;
the liquid preparation container is communicated with an inlet of the liquid extracting pump through a liquid extracting pipe, and a second electromagnetic valve is arranged on the liquid extracting pipe; a two-position three-way electromagnetic valve is arranged on the liquid discharge pipe, a third interface of the two-position three-way electromagnetic valve is communicated with the liquid injection main pipe, each liquid injection branch pipe communicated with the liquid injection main pipe is communicated with one sub-packaging container, and a third electromagnetic valve is arranged on each liquid injection branch pipe;
the liquid extracting pump is used for pumping the reagent in the second reagent container to the liquid preparation container to form an automatic liquid feeding system; the liquid pump drops the reagent in the liquid preparation container into the liquid preparation container through a liquid discharge pipe to form a circulating and uniformly mixing loop; and the liquid pump injects the uniformly mixed reagent in the liquid preparation container into each sub-packaging container through the liquid discharge pipe, the liquid injection main pipe and the liquid injection branch pipe to form an automatic liquid injection system.
The outlet end of the liquid discharge pipe extends to the upper part of the liquid preparation container, and the inlet end of the liquid suction pipe extends to the bottom of the liquid preparation container.
And a first weight sensor is arranged below the liquid preparation container, and a second weight sensor is arranged below each subpackaging container.
The first reagent container is communicated with the inlet of the liquid extracting pump through a connecting pipe with a fourth electromagnetic valve.
The utility model discloses the advantage lies in using an drawing liquid pump to realize the automatic partial shipment of adding, automatic mixing and mixing reagent of reagent, simple structure, ingenious, with low costs, easy operation, join in marriage that liquid is fast and the precision is high, not only can be used to the dilution of concentrate, can also be used to the mixture between the different reagents and join in marriage liquid. The method comprises the following specific steps:
1) the utility model realizes automatic liquid feeding, mixing and filling by using one liquid pump, and has simple and ingenious structure, low cost and low requirement on the liquid pump; meanwhile, the utility model utilizes the signal fed back by the first weight sensor to accurately control the weight ratio of the raw material reagent, and the proportioning precision is high; and the signal fed back by the second weight sensor is used for automatically subpackaging the uniformly mixed reagent, so that the manual auxiliary operation is not needed, and the pollution is reduced.
2) When the utility model is mixed, the inlet end of the liquid suction pipe extends to the bottom of the liquid preparation container, the outlet end of the liquid discharge pipe extends to the upper part of the liquid preparation container on the opposite side of the liquid suction pipe, the liquid suction pipe absorbs liquid from the bottom of one side of the liquid preparation container in the mixing process, and the liquid suction pipe falls on the other side of the liquid preparation container in suspension to ensure the mixing effect; simultaneously the utility model discloses can be regularly to the automatic mixing once more of mixing reagent after mixing, prevent that the crystallization from appearing because of the dwell time overlength in the mixing reagent of crystallinity.
3) The utility model discloses an automatic liquid system, circulation mixing return circuit and automatic liquid system sharing suction pump of annotating in going up, three pipelines can switch at will, and non-crystalline raw materials reagent can wash the drawing liquid pump when going up liquid, avoids crystalline raw materials reagent to block up the pump valve of drawing liquid pump.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic block circuit diagram of the present invention.
Fig. 3 is the flow chart of the automatic blending of the present invention.
Fig. 4 is a flow chart of the automatic liquid injection of the present invention.
Detailed Description
The present invention will be described in more detail below with reference to the accompanying drawings, taking the dilution of BF concentrated solution used in the detection of the in vitro diagnostic apparatus as an example.
As shown in figure 1, the automatic solution diluting system of the present invention comprises a first reagent container 1.1 for containing BF concentrated solution and a second reagent container 1.2 (which may be a reagent bottle or a reagent barrel, or a purified water maker) for containing purified water (i.e. a diluent), wherein if there are two or more diluents, the second reagent container is correspondingly two or more, the second reagent container 1.2 is communicated with an inlet of a liquid pump 3 through a delivery pipe 2, an outlet of the liquid pump 3 is communicated with a liquid preparation container 5 with a first weight sensor 11 placed at the bottom through a liquid discharge pipe 4, and the delivery pipe 2 is provided with a first electromagnetic valve 6.1;
the liquid preparation container 5 is communicated with an inlet of the liquid pump 3 through a liquid pumping pipe 7, and a second electromagnetic valve 6.2 is arranged on the liquid pumping pipe 7; a two-position three-way electromagnetic valve 8 is arranged on the liquid discharge pipe 4, the other interface of the two-position three-way electromagnetic valve 8 is communicated with a liquid injection main pipe 9.1, each liquid injection branch pipe 9.2 of the liquid injection main pipe 9.1 is communicated with a sub-packaging container 10 with a second weight sensor 12 arranged at the bottom, and a third electromagnetic valve 6.3 controlled by a control system is arranged on each liquid injection branch pipe 9.2;
the outlet end of the liquid discharge pipe 4 extends to the upper part of the liquid preparation container 5, and the inlet end of the liquid pumping pipe 7 extends to the bottom of the liquid preparation container 5, so that the purified water and the concentrated liquid are low in height and fall down, and uniform mixing is ensured;
wherein, the liquid pump 3 pumps the purified water in the second reagent container 1.2 to the liquid preparation container 5 to form an automatic liquid feeding system; the liquid pump 3 makes the reagent in the liquid preparation container 5 fall into the liquid preparation container 5 through the liquid discharge pipe 4 to form a circular mixing loop; and the liquid pump 3 injects the uniformly mixed reagent in the liquid preparation container 5 into each sub-packaging container 10 through the liquid discharge pipe 4, the liquid injection main pipe 9.1 and the liquid injection branch pipe 9.2 to form an automatic liquid injection system.
As shown in fig. 2, the first weight sensor 11 and the plurality of second weight sensors 12 are electrically connected to a control system (which may be a PLC control system of an in vitro diagnostic apparatus), the control system is configured to receive weight signals detected by the first weight sensor 11 and the second weight sensor 12, and the control system is respectively electrically connected to the first electromagnetic valve 6.1, the second electromagnetic valve 6.2, the third electromagnetic valve, the two-position three-way electromagnetic valve 8, and the drawing liquid pump 3, and is configured to control on/off conditions of the first electromagnetic valve 6.1, the second electromagnetic valve 6.2, and the third electromagnetic valve, and is further configured to control on/off of the drawing liquid pump 3 and a working state of the two-position three-way electromagnetic valve 8, thereby achieving automatic liquid feeding, automatic mixing, and automatic dispensing of the diluent.
When the system works, a user manually pours BF concentrated solution in the first reagent container 1.1 into the solution preparation container 5, the first weight sensor 11 transmits a detected weight signal to the control system, and the control system controls the liquid pump 3 to add purified water into the solution preparation container 5 according to a set proportion; then the mixed reagent in the liquid preparation container 5 flows into the liquid preparation container 5 again through the liquid discharge pipe 4 by using the liquid drawing pump 3; after the misce bene, utilize drawing liquid pump 3 to pass through fluid-discharge tube 4 with annotate the BF washing liquid after the dilution misce bene and be responsible for 9.1, annotate liquid branch pipe 9.2 and pour into partial shipment container 10 in proper order in, accomplish the automatic branch of BF washing liquid and annotate, specifically include with the content:
firstly, when the control system identifies that the liquid preparation container 5 is an empty bottle, the control system reminds a user to pour BF concentrated liquid into the liquid preparation container 5, then the control system sends an instruction to the liquid drawing pump 3 and the first electromagnetic valve 6.1 to enable the automatic liquid feeding system to be in a channel, the liquid drawing pump 3 conveys purified water into the liquid preparation container 5 according to the system until the weight ratio of the BF concentrated liquid to the purified water reaches a preset ratio, and the liquid drawing pump 3 and the first electromagnetic valve 6.1 are closed to finish liquid feeding operation of the BF concentrated liquid and the purified water;
secondly, after the purified water is added, the control system sends an instruction to the liquid pump 3, the second electromagnetic valve 6.2 and the two-position three-way electromagnetic valve 8 to enable the circulating and uniformly mixing loop to be in a passage, the liquid pump 3 pumps the mixed reagent in the liquid preparation container 5 to enable the mixed reagent to fall into the liquid preparation container 5 again after passing through the liquid discharge pipe 4 and the liquid discharge pipe 4, and after the purified water is uniformly mixed for a preset time, diluted and uniformly mixed BF cleaning liquid is obtained for later use;
when the BF cleaning solution prepared in the solution preparation container 5 is used up, repeating the first step and the second step to ensure that sufficient BF cleaning solution is in the solution preparation container 5 so as to meet the normal working requirement of the in-vitro diagnostic equipment; meanwhile, if more than 12 hours after the BF cleaning solution in the solution preparation container 5 is mixed uniformly, mixing uniformly again before injecting liquid, wherein the specific flow chart is shown in FIG. 3;
thirdly, after uniformly mixing the BF concentrated solution and the purified water, when the weight of the BF cleaning solution in any one of the subpackaging containers 10 reaches a preset lower limit value, the control system sends an instruction to the liquid pumping pump 3, the two-position three-way electromagnetic valve 8 and the third electromagnetic valve 6.3 to enable the automatic liquid injection system to be in a channel, the liquid pumping pump 3 injects the uniformly mixed solution in the liquid preparation container 5 into the subpackaging container 10 until the total weight of the subpackaging containers 10 reaches a preset upper limit value, the liquid pumping pump 3 stops working, the third electromagnetic valve 6.3 is switched off, and the automatic liquid injection of the subpackaging container 10 is completed; if the blending reagent in the liquid preparation container 5 is insufficient, stopping subpackaging and injecting, repeating the first step and the second step, and then continuously subpackaging and injecting, wherein the specific injection flow is shown in fig. 4;
when the weight of the diluted cleaning solution in any two of the sub-packaging containers 10 reaches a preset lower limit value, the two-position three-way electromagnetic valve 8 is communicated with the main liquid injection pipe 9.1, the corresponding two third electromagnetic valves 6.3 are opened, the liquid pumping pump 3 operates to simultaneously inject the diluted cleaning solution into the two sub-packaging containers 10 until the weight of the cleaning solution in each sub-packaging container 10 reaches the preset upper limit value, the liquid pumping pump 3 stops operating, and the third electromagnetic valve 6.3 corresponding to the sub-packaging container 10 is disconnected; similarly, when three or four or more containers reach the preset lower limit, the control system may control the liquid pump 3 to simultaneously inject the cleaning liquid into three, four or more dispensing containers 10.
The automatic solution diluting system of the utility model can be used for diluting concentrated solution and preparing mixed solution of two or more reagents; meanwhile, for the concentrated solution which is low in viscosity and difficult to crystallize, the first reagent container can be communicated with the inlet of the liquid pump 3 through a connecting pipe with a fourth electromagnetic valve, so that all reagents can be automatically fed.
Claims (4)
1. An automatic solution dilution system, characterized by: the device comprises a first reagent container (1.1) and at least one second reagent container (1.2), wherein each second reagent container (1.2) is communicated with an inlet of a liquid drawing pump (3) through a conveying pipe (2), an outlet of the liquid drawing pump (3) is communicated with a liquid distribution container (5) through a liquid discharge pipe (4), and a first electromagnetic valve (6.1) is arranged on the conveying pipe (2);
the liquid preparation container (5) is communicated with an inlet of the liquid pump (3) through a liquid pumping pipe (7), and a second electromagnetic valve (6.2) is arranged on the liquid pumping pipe (7); a two-position three-way electromagnetic valve (8) is arranged on the liquid discharge pipe (4), a third interface of the two-position three-way electromagnetic valve (8) is communicated with a liquid injection main pipe (9.1), each liquid injection branch pipe (9.2) communicated with the liquid injection main pipe (9.1) is communicated with one subpackaging container (10), and a third electromagnetic valve (6.3) is arranged on each liquid injection branch pipe (9.2);
the liquid pump (3) pumps the reagent in the second reagent container (1.2) to the liquid preparation container (5) to form an automatic liquid feeding system; the liquid pump (3) drops the mixed reagent in the liquid preparation container (5) into the liquid preparation container (5) through the liquid discharge pipe (4) to form a circular mixing loop; the liquid pump (3) injects the blending reagent in the liquid preparation container (5) into each sub-packaging container (10) through the liquid discharge pipe (4), the liquid injection main pipe (9.1) and the liquid injection branch pipe (9.2) to form an automatic liquid injection system.
2. The solution auto-dilution system according to claim 1, wherein: the outlet end of the liquid discharge pipe (4) extends to the upper part of the liquid preparation container (5), and the inlet end of the liquid suction pipe (7) extends to the bottom of the liquid preparation container (5).
3. The solution auto-dilution system according to claim 1, wherein: a first weight sensor (11) is arranged below the liquid preparation container (5), and a second weight sensor (12) is arranged below each sub-packaging container (10).
4. The solution auto-dilution system according to claim 1, wherein: the first reagent container (1.1) is communicated with the inlet of the liquid pump (3) through a connecting pipe with a fourth electromagnetic valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020786954.0U CN212142185U (en) | 2020-05-13 | 2020-05-13 | Automatic solution diluting system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020786954.0U CN212142185U (en) | 2020-05-13 | 2020-05-13 | Automatic solution diluting system |
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| CN212142185U true CN212142185U (en) | 2020-12-15 |
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| CN202020786954.0U Active CN212142185U (en) | 2020-05-13 | 2020-05-13 | Automatic solution diluting system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113617285A (en) * | 2021-09-01 | 2021-11-09 | 苏州立禾生物医学工程有限公司 | Automatic liquid preparation device |
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2020
- 2020-05-13 CN CN202020786954.0U patent/CN212142185U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113617285A (en) * | 2021-09-01 | 2021-11-09 | 苏州立禾生物医学工程有限公司 | Automatic liquid preparation device |
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