CN212120162U - Preparation facilities of silodosin bulk drug - Google Patents

Preparation facilities of silodosin bulk drug Download PDF

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Publication number
CN212120162U
CN212120162U CN202020483150.3U CN202020483150U CN212120162U CN 212120162 U CN212120162 U CN 212120162U CN 202020483150 U CN202020483150 U CN 202020483150U CN 212120162 U CN212120162 U CN 212120162U
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CN
China
Prior art keywords
fixedly connected
charging barrel
plate
silodosin
bulk drug
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CN202020483150.3U
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Chinese (zh)
Inventor
王先登
毛逸飞
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Meirui Pharmaceutical Co ltd Nanjing
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Meirui Pharmaceutical Co ltd Nanjing
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Priority to CN202020483150.3U priority Critical patent/CN212120162U/en
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Abstract

The utility model relates to a preparation technical field of silodosin bulk drug, and a preparation facilities of silodosin bulk drug is disclosed, feed cylinder and bottom plate including the cylinder structure, be provided with the annular slab of matching in the feed cylinder, and annular slab rotates with the feed cylinder inner wall to be connected, the annular slab separates the feed cylinder for transmission chamber and grinding chamber from a left side to the right side in proper order, the outer tip fixedly connected with U template in transmission chamber is kept away from to the feed cylinder, fixed mounting has driving motor in the U template, driving motor's output passes through shaft coupling fixedly connected with pivot, the center department that the other end of pivot runs through the feed cylinder tip extends to its inner chamber and annular slab fixed connection, rotate through first seal bearing between pivot and the feed cylinder tip and be connected, be located the equal symmetrical fixedly connected with branch of upper surface and lower surface of pivot. The utility model discloses make silodosin bulk drug conveniently carry out the particle size screening to the powder after grinding in the preparation process to effectively guarantee to grind the effect.

Description

Preparation facilities of silodosin bulk drug
Technical Field
The utility model relates to a preparation technical field of silodosin bulk drug especially relates to a preparation facilities of silodosin bulk drug.
Background
The silodosin raw material medicine is white to yellowish powder, and production raw materials of the silodosin raw material medicine are crushed and ground to obtain powdery raw material medicine when the silodosin raw material medicine is produced and prepared.
The powder preparation process of the silodosin raw material medicine in the prior art is generally prepared by grinding, the grinding effect of the existing preparation device is poor, the particle size of the powder is inconvenient to screen after grinding, and the particle size of the ground powder is different.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the problem that the siro doxine bulk drug is inconvenient to filter the particle diameter of powder in the preparation process in the prior art, influences the grinding effect, and the preparation device of the siro doxine bulk drug that provides.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a device for preparing silodosin raw material medicine comprises a charging barrel and a bottom plate of a cylindrical structure, wherein a matched annular plate is arranged in the charging barrel, the annular plate is rotatably connected with the inner wall of the charging barrel, the annular plate sequentially separates the charging barrel into a transmission cavity and a grinding cavity from left to right, the outer end part of the charging barrel, far away from the transmission cavity, is fixedly connected with a U-shaped plate, a driving motor is fixedly arranged in the U-shaped plate, the output end of the driving motor is fixedly connected with a rotating shaft through a coupler, the other end of the rotating shaft penetrates through the center of the end part of the charging barrel and extends to the inner cavity of the charging barrel to be fixedly connected with the annular plate, the rotating shaft is rotatably connected with the end part of the charging barrel through a first sealing bearing, supporting rods are symmetrically and fixedly connected with the upper surface and the lower surface of the rotating shaft in, the grinding roller is characterized in that the centers of two ends of the grinding roller are respectively fixedly connected with a transmission rod and a first rotating pin, the first rotating pin is rotatably connected with a corresponding supporting rod through a first bearing, one end, far away from the grinding roller, of the transmission rod penetrates through an annular plate and extends into a transmission cavity, the transmission rod is rotatably connected with the annular plate through a second sealing bearing, an annular gear ring is fixedly mounted on the inner wall of the transmission cavity, a driving gear meshed with the annular gear ring is fixedly sleeved at the end position, far away from the grinding roller, of the transmission rod, an opening is formed in the top of the grinding cavity, a hopper in a rectangular structure is fixedly connected in the opening, a matched rectangular frame is hinged on the edge of the hopper, a matched screening net is fixedly mounted in the rectangular frame, a side plate is symmetrically and fixedly connected to the upper surface of the bottom plate, close to the end, and one side, far away from the charging barrel, and the second rotating pin is rotatably connected with the corresponding side plate through a second bearing, the outer end part of the charging barrel, which is far away from the U-shaped plate, is fixedly connected with a rotating rod, the other end of the rotating rod penetrates through the corresponding side plate, the rotating rod is rotatably connected with the side plate, a rotating disc is fixedly sleeved on the rotating rod, and a deflection positioning mechanism is installed between the rotating disc and the corresponding side plate.
Preferably, the deflection positioning mechanism is including seting up the sliding tray that the carousel is close to on the top lateral wall, sliding tray sliding connection has the fixture block of matching, fixedly connected with spring between fixture block and the sliding tray tank bottom, one side fixedly connected with pull rod that the fixture block is close to the sliding tray tank bottom, the tank bottom that the other end of pull rod passed the spring and runs through the sliding tray outwards extends, and the tank bottom sliding connection of pull rod and sliding tray, the draw-in groove that matches with the fixture block is seted up to one side symmetry that the curb plate is close to the carousel, the one end that the spring was kept away from to the fixture block passes the notch of sliding tray and extends to one of them draw.
Preferably, the axes of the rotating shaft, the annular plate, the charging barrel, the second rotating pin and the rotating rod are all arranged in a superposition mode.
Preferably, the top and the bottom of annular plate all fixedly connected with slider, the inner wall of feed cylinder is seted up the ring channel that matches with the slider, and slider and ring channel sliding connection.
Preferably, the four corners of the bottom plate are provided with positioning holes.
Preferably, the rectangular frame is connected with the hopper through a buckle.
Preferably, one end of the pull rod, which is far away from the fixture block, is fixedly connected with a pull ring.
Preferably, the top end and the bottom end of the rotating disc are both fixedly connected with a deflection rod.
Preferably, a ball groove is formed in one side, close to the bottom of the annular groove, of the sliding block, matched balls are installed in the ball groove, one end, far away from the bottom of the ball groove, of each ball penetrates through the groove opening of the corresponding ball groove and extends outwards, and the ball is connected to the bottom of the annular groove in a rolling mode.
Compared with the prior art, the utility model provides a preparation facilities of silodosin bulk drug possesses following beneficial effect:
the device for preparing the silodosin raw material drug is provided with a charging barrel, an annular plate, a U-shaped plate, a driving motor, a rotating shaft, a supporting rod, a grinding roller, a transmission rod, an annular gear ring, a driving gear, a hopper, a rectangular frame, a screening net, a rotating rod, a rotary disc and a deflection positioning mechanism, wherein the rectangular frame connected by a hinge is opened, so that raw materials are conveniently added into a grinding cavity of the charging barrel through the hopper, the driving motor is started to drive the rotating shaft to rotate, the rotating shaft drives the supporting rod and the transmission rod to move synchronously, the annular plate is driven by the supporting rod to rotate in the inner cavity of the charging barrel, the driving gear on the transmission rod is meshed with the annular gear ring in the transmission cavity, so that the transmission rod rotates automatically, the transmission rod drives the grinding roller to rotate, the raw materials are conveniently and fully ground by matching with the inner, can drive the feed cylinder when the bull stick rotates and carry out the rotation to conveniently make the hopper invert, the powder after the grinding can fall to the screening net of rectangle frame via the hopper under the action of gravity on, the powder that accords with the particle size will be collected through concentrating, will continue to stay conveniently in the feed cylinder and carry out follow-up grinding not conform to the powder of particle size, so relapse, make silodosin bulk drug conveniently screen the powder particle size after the grinding in preparation process, thereby effectively guarantee grinding effect.
The part that does not relate to in the device all is the same with prior art or can adopt prior art to realize, the utility model discloses make silodosin bulk drug conveniently carry out the particle size screening to the powder after grinding in the preparation process to effectively guarantee to grind the effect.
Drawings
Fig. 1 is a schematic structural diagram of a device for preparing silodosin bulk drug provided by the present invention;
fig. 2 is a schematic structural diagram of a connection portion between a rectangular frame and a screening net of a device for preparing a silodosin crude drug provided by the present invention;
FIG. 3 is an enlarged view of portion A of FIG. 1;
fig. 4 is an enlarged view of a portion B in fig. 1.
In the figure: the grinding machine comprises a charging barrel 1, a bottom plate 2, an annular plate 3, a U-shaped plate 4, a driving motor 5, a rotating shaft 6, a supporting rod 7, a grinding roller 8, a transmission rod 9, an annular gear ring 10, a driving gear 11, a hopper 12, a rectangular frame 13, a screening net 14, a side plate 15, a rotating rod 16, a rotating disc 17, a sliding groove 18, a clamping block 19, a spring 20, a pull rod 21, a clamping groove 22, a sliding block 23, a ring groove 24, a pull ring 25, a deflection rod 26 and a ball 27.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
Referring to fig. 1-4, a device for preparing silodosin raw material medicine comprises a cylinder 1 and a bottom plate 2, wherein the cylinder 1 is provided with a matched annular plate 3, the annular plate 3 is rotatably connected with the inner wall of the cylinder 1, the cylinder 1 is sequentially divided into a transmission cavity and a grinding cavity from left to right by the annular plate 3, the outer end part of the cylinder 1 far away from the transmission cavity is fixedly connected with a U-shaped plate 4, a driving motor 5 is fixedly installed in the U-shaped plate 4, the output end of the driving motor 5 is fixedly connected with a rotating shaft 6 through a coupler, the other end of the rotating shaft 6 penetrates through the center of the end part of the cylinder 1 and extends to the inner cavity thereof to be fixedly connected with the annular plate 3, the rotating shaft 6 is rotatably connected with the end part of the cylinder 1 through a first sealing bearing, supporting rods 7 are symmetrically and fixedly connected with the upper surface and the lower surface of, the grinding roller 8 is connected with the inner wall of the grinding cavity in a rolling way, the centers of two ends of the grinding roller 8 are respectively and fixedly connected with a transmission rod 9 and a first rotating pin, the first rotating pin is connected with a corresponding supporting rod 7 in a rotating way through a first bearing, one end of the transmission rod 9, far away from the grinding roller 8, penetrates through the annular plate 3 and extends into the transmission cavity, the transmission rod 9 is connected with the annular plate 3 in a rotating way through a second sealing bearing, an annular gear ring 10 is fixedly arranged on the inner wall of the transmission cavity, a driving gear 11 meshed with the annular gear ring 10 is fixedly sleeved at the end part of the transmission rod 9, far away from the grinding roller 8, an opening is arranged at the top of the grinding cavity, a hopper 12 in a rectangular structure is fixedly connected in the opening, a matched rectangular frame 13 is hinged on the edge of the hopper 12, a matched screening net 14 is fixedly arranged in the rectangular frame 13, and a side plate, one side of the U-shaped plate 4, which is far away from the charging barrel 1, is fixedly connected with a second rotating pin, the second rotating pin is rotatably connected with a corresponding side plate 15 through a second bearing, the outer end part of the charging barrel 1, which is far away from the U-shaped plate 4, is fixedly connected with a rotating rod 16, the other end of the rotating rod 16 penetrates through the corresponding side plate 15, the rotating rod 16 is rotatably connected with the side plate 15, a rotating disk 17 is fixedly sleeved on the rotating rod 16, a deflection positioning mechanism is installed between the rotating disk 17 and the corresponding side plate 15, a rectangular frame 13 connected with a hinge is opened, so that raw materials are conveniently added into a grinding cavity of the charging barrel 1 through a hopper 12, a driving motor 5 is started to drive a rotating shaft 6 to rotate, the rotating shaft 6 drives a supporting rod 7 and a driving rod 9 to synchronously move, the supporting rod 7 drives a ring-shaped plate 3 to rotate in the inner cavity of the charging barrel 1, the inner wall of chamber is ground in the cooperation is convenient fully grinds the raw materials, grind after the suitable time, it rotates carousel 17 and drives bull stick 16 and rotate, bull stick 16 can drive feed cylinder 1 when rotating and carry out the rotation, the feed cylinder rotates 180 degrees back hopper 12 and takes place to invert, powder after the grinding can fall to on rectangular frame 13's screening net 14 via hopper 12 under the action of gravity, the powder that accords with the particle size will be through concentrating the collection, it will continue to stay in feed cylinder 1 conveniently to carry out follow-up grinding to be not conform to the powder of particle size, so relapse, make silodosin's material medicine conveniently filter the powder particle size after grinding at the preparation in-process, thereby effectively guarantee grinding effect.
The deflection positioning mechanism comprises a sliding groove 18 arranged on the side wall of the turntable 17 close to the top end, a matched clamping block 19 is connected in the sliding groove 18 in a sliding mode, a spring 20 is fixedly connected between the clamping block 19 and the bottom of the sliding groove 18, a pull rod 21 is fixedly connected to one side of the clamping block 19 close to the bottom of the sliding groove 18, the other end of the pull rod 21 penetrates through the spring 20 and penetrates through the bottom of the sliding groove 18 to extend outwards, the pull rod 21 is connected with the bottom of the sliding groove 18 in a sliding mode, clamping grooves 22 matched with the clamping block 19 are symmetrically formed in one side of the side plate 15 close to the turntable 17, one end of the clamping block 19 far away from the spring 20 penetrates through the groove opening of the sliding groove 18 and extends into one corresponding clamping groove 22, the turntable 17 can rotate by driving the pull rod 21 to drive the clamping block 19 to slide into the sliding groove 18 and compress the spring 20, so that the rotary table is clamped with the corresponding clamping groove 22, thereby conveniently locking the position of the rotary table 17
The axes of the rotating shaft 6, the annular plate 3, the charging barrel 1, the second rotating pin and the rotating rod 16 are overlapped, and coaxial rotation is guaranteed.
The equal fixedly connected with slider 23 in top and the bottom of annular plate 3, the ring channel 24 who matches with slider 23 is seted up to the inner wall of feed cylinder 1, and slider 23 and ring channel 24 sliding connection improve annular plate 3 pivoted stability.
The locating hole has all been seted up to the four corners department of 2 bottoms of bottom plates, makes things convenient for bottom plate 2 to fix a position the installation.
The rectangular frame 13 is connected with the hopper 12 through a buckle, so that the opening and closing of the rectangular frame 13 are controlled conveniently.
One end of the pull rod 21, which is far away from the fixture block 19, is fixedly connected with a pull ring 25, so that the pull rod 21 is conveniently driven to slide.
The top end and the bottom end of the rotary table 17 are both fixedly connected with deflection rods 26, so that the rotary table 17 can be conveniently driven to rotate.
The ball groove has been seted up to one side that slider 23 is close to ring channel 24 tank bottom, and installs the ball 27 that matches in the ball groove, and the ball 27 one end of keeping away from the ball groove tank bottom passes the notch in ball groove and outwards extends, and roll connection is at the tank bottom of ring channel 24, reduces the frictional force between slider 23 and the ring channel 24.
In the utility model, the rectangular frame 13 connected by the hinge is opened, raw materials are conveniently added into the grinding cavity of the charging barrel 1 through the hopper 12, the driving motor 5 is started to drive the rotating shaft 6 to rotate, the rotating shaft 6 drives the supporting rod 7 and the transmission rod 9 to move synchronously, the supporting rod 7 drives the annular plate 3 to rotate in the inner cavity of the charging barrel 1, the driving gear 11 on the transmission rod 9 is meshed with the annular gear ring 10 in the transmission cavity, so that the transmission rod 9 rotates automatically, the transmission rod 9 drives the grinding roller 8 to rotate, the raw materials are ground fully by matching with the inner wall of the grinding cavity, after grinding for a proper time, the pull rod 21 is pulled to drive the fixture block 19 to slide into the sliding groove 18 and compress the spring 20, the rotating turntable 17 drives the rotating rod 16 to rotate, the charging barrel 1 can be driven to rotate when the rotating rod 16 rotates, the pull rod 21 is loosened after the charging barrel 1 rotates 180 degrees, the, thereby conveniently lock carousel 17's position, hopper 12 takes place to invert after the feed cylinder rotates 180 degrees, powder after the grinding can fall to rectangular frame 13's screening net 14 on via hopper 12 under the action of gravity, the powder that accords with the particle size will be through concentrating the collection, it will continue to stay in feed cylinder 1 conveniently to carry out follow-up grinding to be not conform to the powder of particle size, so relapse, make silodosin bulk drug conveniently screen the powder particle size after the grinding in preparation process, thereby effectively guarantee the grinding effect.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims (9)

1. The preparation device of the silodosin raw material medicine comprises a charging barrel (1) and a bottom plate (2) which are of a cylindrical structure, and is characterized in that a matched annular plate (3) is arranged in the charging barrel (1), the annular plate (3) is rotatably connected with the inner wall of the charging barrel (1), the annular plate (3) sequentially separates the charging barrel (1) from left to right into a transmission cavity and a grinding cavity, the outer end part of the charging barrel (1), far away from the transmission cavity, is fixedly connected with a U-shaped plate (4), a driving motor (5) is fixedly arranged in the U-shaped plate (4), the output end of the driving motor (5) is fixedly connected with a rotating shaft (6) through a coupler, the other end of the rotating shaft (6) penetrates through the center of the end part of the charging barrel (1) and extends to the inner cavity of the rotating shaft and the annular plate (3), and the rotating shaft (6) is rotatably connected with the, the upper surface and the lower surface of the rotating shaft (6) in the charging barrel (1) are symmetrically and fixedly connected with supporting rods (7), a grinding roller (8) is arranged between the supporting rods (7) horizontally, the grinding roller (8) is connected with the inner wall of a grinding cavity in a rolling manner, the centers of the two ends of the grinding roller (8) are respectively and fixedly connected with a transmission rod (9) and a first rotating pin, the first rotating pin is rotatably connected with the corresponding supporting rods (7) through a first bearing, one end, far away from the grinding roller (8), of the transmission rod (9) penetrates through the annular plate (3) and extends into the transmission cavity, the transmission rod (9) is rotatably connected with the annular plate (3) through a second sealing bearing, an annular gear ring (10) is fixedly arranged on the inner wall of the transmission cavity, and a driving gear (11) meshed with the annular gear ring (10) is fixedly sleeved at the position of the end part, far away from the grinding roller (8), of the transmission, the top of the grinding cavity is provided with an opening, a hopper (12) with a rectangular structure is fixedly connected in the opening, the edge of the hopper (12) is hinged with a matched rectangular frame (13), and a matched screening net (14) is fixedly arranged in the rectangular frame (13), the upper surface of the bottom plate (2) close to the end part is symmetrically and fixedly connected with side plates (15), one side of the U-shaped plate (4) far away from the charging barrel (1) is fixedly connected with a second rotating pin, the second rotating pin is rotatably connected with the corresponding side plate (15) through a second bearing, the outer end part of the charging barrel (1) far away from the U-shaped plate (4) is fixedly connected with a rotating rod (16), the other end of the rotating rod (16) penetrates through the corresponding side plate (15), and the rotating rod (16) is rotationally connected with the side plate (15), the rotating rod (16) is fixedly sleeved with a turntable (17), and a deflection positioning mechanism is arranged between the rotary disc (17) and the corresponding side plate (15).
2. The device for preparing silodosin bulk drug according to claim 1, wherein the deflecting and positioning mechanism comprises a sliding groove (18) formed in a side wall of the turntable (17) near the top end, a matching clamping block (19) is slidably connected in the sliding groove (18), a spring (20) is fixedly connected between the clamping block (19) and a bottom of the sliding groove (18), a pull rod (21) is fixedly connected to one side of the clamping block (19) near the bottom of the sliding groove (18), the other end of the pull rod (21) penetrates through the spring (20) and extends outwards through the bottom of the sliding groove (18), the pull rod (21) is slidably connected with the bottom of the sliding groove (18), clamping grooves (22) matched with the clamping block (19) are symmetrically formed in one side of the side plate (15) near the turntable (17), one end of the clamping block (19) far away from the spring (20) penetrates through a notch of the sliding groove (18) and extends to one corresponding clamping groove (22) arranged in the sliding groove .
3. The apparatus for preparing silodosin bulk drug according to claim 1, wherein the axes of the rotating shaft (6), the annular plate (3), the charging barrel (1), the second rotating pin and the rotating rod (16) are all coincidently arranged.
4. The device for preparing silodosin raw material medicine according to claim 1, wherein the top end and the bottom end of the annular plate (3) are both fixedly connected with a sliding block (23), the inner wall of the charging barrel (1) is provided with an annular groove (24) matched with the sliding block (23), and the sliding block (23) is slidably connected with the annular groove (24).
5. The apparatus for preparing silodosin bulk drug according to claim 1, wherein the bottom of the bottom plate (2) has positioning holes at four corners.
6. The apparatus for preparing silodosin bulk drug according to claim 1, wherein the rectangular frame (13) is connected to the hopper (12) by a snap.
7. The apparatus for preparing silodosin bulk drug according to claim 2, wherein a pull ring (25) is fixedly connected to an end of the pull rod (21) away from the latch (19).
8. The apparatus for preparing silodosin bulk drug according to claim 2, wherein the top end and the bottom end of the rotating disc (17) are fixedly connected with deflecting bars (26).
9. The device for preparing silodosin bulk drug according to claim 4, wherein the side of the slide block (23) close to the bottom of the annular groove (24) is provided with a ball groove, and a matching ball (27) is mounted in the ball groove, and one end of the ball (27) far away from the bottom of the ball groove passes through the notch of the ball groove and extends outwards, and is connected to the bottom of the annular groove (24) in a rolling manner.
CN202020483150.3U 2020-04-07 2020-04-07 Preparation facilities of silodosin bulk drug Active CN212120162U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020483150.3U CN212120162U (en) 2020-04-07 2020-04-07 Preparation facilities of silodosin bulk drug

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020483150.3U CN212120162U (en) 2020-04-07 2020-04-07 Preparation facilities of silodosin bulk drug

Publications (1)

Publication Number Publication Date
CN212120162U true CN212120162U (en) 2020-12-11

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Application Number Title Priority Date Filing Date
CN202020483150.3U Active CN212120162U (en) 2020-04-07 2020-04-07 Preparation facilities of silodosin bulk drug

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CN (1) CN212120162U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116212679A (en) * 2023-05-11 2023-06-06 烟台伟昌电子材料有限公司 Mixing equipment for preparing epoxy resin sealant and preparation process thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116212679A (en) * 2023-05-11 2023-06-06 烟台伟昌电子材料有限公司 Mixing equipment for preparing epoxy resin sealant and preparation process thereof
CN116212679B (en) * 2023-05-11 2023-08-04 烟台伟昌电子材料有限公司 Mixing equipment for preparing epoxy resin sealant and preparation process thereof

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