CN212060275U - Parallel device for rapidly detecting glycosylated hemoglobin at bedside - Google Patents

Parallel device for rapidly detecting glycosylated hemoglobin at bedside Download PDF

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Publication number
CN212060275U
CN212060275U CN202020186993.7U CN202020186993U CN212060275U CN 212060275 U CN212060275 U CN 212060275U CN 202020186993 U CN202020186993 U CN 202020186993U CN 212060275 U CN212060275 U CN 212060275U
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reaction cup
reagent chamber
connecting pipe
reagent
bedside
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黄磊
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Jiangsu Shenji Biotechnology Co ltd
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Jiangsu Shenji Biotechnology Co ltd
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Abstract

The utility model discloses a bedside short-term test glycated hemoglobin's parallel arrangement, including first reagent room, connecting pipe, reaction cup and second reagent room, the capillary is installed to reaction cup's bottom, and capillary bottom is provided with the second pore, the heating piece is all installed at the inside both ends of reaction cup, temperature sensor is installed to the inside bottom of reaction cup, be provided with the polyethylene anticorrosive coating on reaction cup's the inside wall, one side that is close to the polyethylene anticorrosive coating on the reaction cup inside wall is provided with the carbon fiber reinforced layer. The utility model discloses an install first push rod, first reagent room, connecting pipe, reaction cup, capillary and third passageway, operating personnel pushes away first piston to the bottom of first reagent room, then aims at the hemorrhage mouth with the third hole way of capillary bottom, outwards extracts first piston until pulling out motionless, accomplishes sample work to the inspection efficiency of device is provided.

Description

Parallel device for rapidly detecting glycosylated hemoglobin at bedside
Technical Field
The utility model relates to a glycosylated hemoglobin parallel device technical field specifically is a bedside short-term test glycosylated hemoglobin's parallel device.
Background
The synthesis rate of the glycosylated hemoglobin is proportional to the concentration of sugar in the environment where the red blood cells are located, the glycosylated hemoglobin is generated by the combination of the hemoglobin in the red blood cells, the product of the combination of the blood glucose and the hemoglobin in the red blood cells of the human body, and the glycosylated hemoglobin is an irreversible reaction, daily detection is performed in clinical detection as an index for blood glucose control, the current main detection method for clinically measuring the glycosylated hemoglobin generally relates to a parallel device of the glycosylated hemoglobin, but the existing parallel device still has some defects in use:
1. the indirect sampling of current device heparin tube and the function of establishing ties and not taking a sample have greatly reduced inspection efficiency and increased the cost.
2. The existing device is mostly fixed, and is inconvenient to detach for a long time for cleaning, so that the practicability of the device is reduced.
3. The existing device has low strength and poor corrosion resistance, so that the device is easy to damage when being impacted by external force, and the service life of the device is greatly shortened.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a bedside short-term test glycosylated hemoglobin's parallel arrangement to solve the problem that can not take a sample, inconvenient washing and life is low that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: a parallel device for rapidly detecting glycosylated hemoglobin at a bedside comprises a first reagent chamber, a connecting pipe, a reaction cup and a second reagent chamber, wherein a capillary tube is arranged at the bottom end of the reaction cup, a second pore channel is formed in the bottom end of the capillary tube, heating blocks are arranged at two ends inside the reaction cup, a temperature sensor is arranged at the bottom end inside the reaction cup, a polyethylene anticorrosive layer is arranged on the inner side wall of the reaction cup, a carbon fiber reinforcing layer is arranged at one side, close to the polyethylene anticorrosive layer, of the inner side wall of the reaction cup, a third pore channel is arranged at the top end of one side of the reaction cup, a time control relay is arranged at the bottom end of one side of the reaction cup, the connecting pipe is arranged at the top end of the reaction cup, the first reagent chamber and the second reagent chamber are respectively arranged at one end, far away from the reaction cup, of the connecting pipe, the bottom end of, the bottom of second reagent room is connected with the other end of connecting pipe through the fourth pore, the inside of first reagent room transversely installs first piston, and the top of first piston is fixed with first push rod, the inside of second reagent room transversely installs the second piston, and the top of second piston installs elevating system, control panel is installed to one side of second reagent room, and control panel's internally mounted has the singlechip, temperature sensor's output passes through the input electric connection of wire and singlechip, and the output of singlechip passes through the input electric connection of wire and time control relay, the output of time control relay passes through the input electric connection of wire and heating block, the output of singlechip and driving motor's input electric connection.
Preferably, the first reagent chamber and the second reagent chamber are uniformly provided with scale marks on one side.
Preferably, the inside bottom in first pore and fourth pore all is provided with the reservation groove, and the top of connecting pipe all is provided with the reservation piece of mutually supporting with the reservation groove to the connecting pipe is "Y" type structure, and the aperture in first pore and fourth pore is 1.5mm simultaneously, evenly be provided with the internal thread on the inside wall in reservation groove, evenly be provided with the external screw thread of mutually supporting with the internal thread on the lateral wall of reservation piece.
Preferably, elevating system has set gradually driving motor, belt pulley mechanism, drive box, drive block, second push rod and screw lead screw from last to down, the internally mounted of drive box has belt pulley mechanism, and the one end at drive box top installs driving motor, and driving motor's output is connected with belt pulley mechanism through the pivot, and the screw lead screw is all installed through the pivot to belt pulley mechanism's output to all be provided with the drive block on the screw lead screw, be fixed with the second push rod between the drive block simultaneously.
Preferably, the number of the heating blocks is two, and the heating blocks are symmetrically distributed around the vertical center line of the reaction cup.
Preferably, the inside of carbon fiber reinforced layer evenly is provided with the strengthening rib, and the strengthening rib all is "T" type structure.
Compared with the prior art, the beneficial effects of the utility model are that:
(1) this parallel arrangement of bedside short-term test glycated hemoglobin through installing first push rod, first reagent room, connecting pipe, reaction cup, capillary and third passageway, operating personnel pushes away first piston to the bottom of first reagent room, then aims at the hemorrhage mouth with the third hole way of capillary bottom, outwards extracts first piston until pulling out motionless, accomplishes sample work to the inspection efficiency of device is provided.
(2) This parallel arrangement of bedside short-term test glycated hemoglobin is through installing the connecting pipe, first pore, the fourth pore, the reservation tank and reservation piece, evenly be provided with the internal thread on the inside wall of reservation tank, evenly be provided with the external screw thread of mutually supporting with the internal thread on the lateral wall of reservation piece, thereby make the device after a period of use, can dismantle the internal thread of reservation piece from the reservation tank, the convenience is dismantled connecting pipe and first pore and second pore, and the washing of being convenient for has embodied the practicality of device.
(3) This parallel arrangement of bedside short-term test glycated hemoglobin is through being provided with the carbon fiber back up coat on the inside wall of reaction cup, and the inside of carbon fiber back up coat evenly is provided with the strengthening rib to make the inner structure of reaction cup more stable, improved the intensity of reaction cup, avoid external force to strike to cause the damage, and then prolonged the life of whole device.
(4) This parallel arrangement of bedside short-term test glycated hemoglobin is through installing reaction cup, heating piece, temperature sensor, singlechip, elevating system and second reagent room, and the device is preset and is hatched temperature and time, and the reagent in the singlechip control elevating system will automatic propelling movement second reagent room after hatching 3min 37 ℃, accomplishes the mixture of all reagents, has improved the work efficiency of device greatly, has reduced work efficiency for the testing result is more accurate.
Drawings
Fig. 1 is a schematic structural view of the present invention;
fig. 2 is a schematic front view of the structure of the present invention;
fig. 3 is an enlarged schematic structural view of a point a in fig. 1 according to the present invention;
FIG. 4 is a schematic sectional view of the reaction cup of the present invention;
fig. 5 is a system block diagram of the present invention.
In the figure: 1. a first push rod; 2. a first piston; 3. a first reagent chamber; 4. a first duct; 5. a connecting pipe; 6. a reaction cup; 7. a temperature sensor; 8. a capillary tube; 9. a second duct; 10. a lifting mechanism; 101. a drive motor; 102. a belt pulley mechanism; 103. a drive box; 104. a drive block; 105. a second push rod; 106. a threaded lead screw; 11. a second reagent chamber; 12. a second piston; 13. a single chip microcomputer; 14. a control panel; 15. a third porthole; 16. a heating block; 17. a fourth porthole; 18. a time control relay; 19. reserving a groove; 20. reserving a block; 21. a polyethylene anticorrosive layer; 22. a carbon fiber reinforcing layer; 23. and (5) reinforcing ribs.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides an embodiment: a parallel device for rapidly detecting glycosylated hemoglobin at the bedside comprises a first reagent chamber 3, a connecting pipe 5, a reaction cup 6 and a second reagent chamber 11, wherein a capillary 8 is installed at the bottom end of the reaction cup 6, a second pore channel 9 is arranged at the bottom end of the capillary 8, heating blocks 16 are installed at two ends of the interior of the reaction cup 6, the number of the heating blocks 16 is two, and the heating blocks 16 are symmetrically distributed about the vertical center line of the reaction cup 6;
because the heating block 16 is internally provided with the resistor, the heating block 16 can preheat the inside of the reaction cup 6 after being electrified, and the heating efficiency of the device is improved;
the bottom end in the reaction cup 6 is provided with a temperature sensor 7, the type of the temperature sensor 7 can be CWDZ1, the inner side wall of the reaction cup 6 is provided with a polyethylene anticorrosive layer 21, one side of the inner side wall of the reaction cup 6, which is close to the polyethylene anticorrosive layer 21, is provided with a carbon fiber reinforced layer 22, reinforcing ribs 23 are uniformly arranged in the carbon fiber reinforced layer 22, and the reinforcing ribs 23 are all in a T-shaped structure;
the reinforcing ribs 23 enable the internal structure of the reaction cup 6 to be more stable, so that the strength of the reaction cup 6 is improved, the situation that the reaction cup is broken or even damaged when falling to the ground is avoided, and the service life of the reaction cup 6 is effectively prolonged;
the top end of one side of the reaction cup 6 is provided with a third hole passage 15, the bottom end of one side of the reaction cup 6 is provided with a time control relay 18, the model of the time control relay 18 can be CC-V2.1, the top end of the reaction cup 6 is provided with a connecting pipe 5, one end of the connecting pipe 5, which is far away from the reaction cup 6, is respectively provided with a first reagent chamber 3 and a second reagent chamber 11, and one side of the first reagent chamber 3 and one side of the second reagent chamber 11 are uniformly provided with scale marks;
so that the staff can read the scale marks to add corresponding reagent amount into the first reagent chamber 3 and the second reagent chamber 11;
the bottom end of the first reagent chamber 3 is connected with one end of a connecting pipe 5 through a first pore passage 4, the bottom end of the second reagent chamber 11 is connected with the other end of the connecting pipe 5 through a fourth pore passage 17, the bottom ends inside the first pore passage 4 and the fourth pore passage 17 are both provided with a reserved groove 19, the top end of the connecting pipe 5 is both provided with a reserved block 20 which is matched with the reserved groove 19, the connecting pipe 5 is of a Y-shaped structure, the aperture of the first pore passage 4 and the aperture of the fourth pore passage 17 are both 1.5mm, the inner side wall of the reserved groove 19 is uniformly provided with internal threads, and the outer side wall of the reserved block 20 is uniformly provided with external threads which are matched with the internal threads;
after the device is used for a period of time, the reserved block 20 can be disassembled from the inside of the reserved groove 19 in a threaded mode, so that the connecting pipe 5 and the first reagent chamber 3 and the second reagent chamber 11 are separated, and the device is convenient to clean;
a first piston 2 is transversely arranged in the first reagent chamber 3, a first push rod 1 is fixed at the top end of the first piston 2, a second piston 12 is transversely arranged in the second reagent chamber 11, and the top end of the second piston 12 is provided with a lifting mechanism 10, the lifting mechanism 10 is provided with a driving motor 101, a belt pulley mechanism 102, a driving box 103, a driving block 104, a second push rod 105 and a threaded screw 106 from top to bottom in sequence, the belt pulley mechanism 102 is arranged in the driving box 103, and one end of the top of the driving box 103 is provided with a driving motor 101, the model of the driving motor 101 can be ZYT46S-10, the output end of the driving motor 101 is connected with the belt pulley mechanism 102 through a rotating shaft, the output ends of the belt pulley mechanism 102 are provided with a threaded screw rod 106 through the rotating shaft, the threaded screw rods 106 are provided with driving blocks 104, and a second push rod 105 is fixed between the driving blocks 104;
the driving motor 101 drives the belt pulley mechanism 102 to rotate through the rotating shaft, so that the belt pulley mechanism 102 drives the threaded screw rod 106 to rotate, and the threaded screw rod 106 is opposite to the thread direction inside the driving block 104, so that the driving block 104 can move on the threaded screw rod 106, and the second push rod 105 can be driven to move downwards or upwards according to the requirement of the device;
control panel 14 is installed to one side of second reagent room 11, and control panel 14's internally mounted has singlechip 13, singlechip 13's model can be AT89C52, temperature sensor 7's output passes through the wire and singlechip 13's input electric connection, and singlechip 13's output passes through the wire and time control relay 18's input electric connection, time control relay 18's output passes through the wire and heating block 16's input electric connection, singlechip 13's output and driving motor 101's input electric connection.
The working principle is as follows: when in use, 20ul of reagent group erythrocyte dissociating agent and polystyrene latex microspheres are packaged in the first reagent chamber 3 in advance by reading scale marks on the first reagent chamber 3 and the second reagent chamber 11, 60ul of mouse anti-human glycated hemoglobin monoclonal antibody and goat anti-mouse polyclonal antibody are packaged in the second reagent chamber 11, an operator takes out the device and pushes the first piston 2 to the bottom of the first reagent chamber 3 through the first push rod 1, then the second pore 9 at the bottom end of the capillary tube 8 is aligned with a blood outlet, the first piston 2 is pulled out until the piston is not pulled out, so that sampling, namely reagent mixing is completed, then the device is placed on matched detection equipment, the heating block 16 is controlled by the singlechip 13 to preheat the inside of the reaction cup 6, the temperature is sensed by the temperature sensor 7, the incubation temperature and the incubation time are preset by the device, after the incubation temperature is 37 ℃ for 3min, time control relay 18 gives singlechip 13 stop heating work with the signal, and through the inside reagent of elevating system 10 automatic propelling movement second reagent room 11, accomplish the mixture of all reagents, can read data after 3min, after using a period, dismantle the connecting pipe 5 and screw thread between first pore 4 and the fourth pore 17, convenient the washing, through set up polyethylene anticorrosive coating 21 on the inside wall at reaction cup 6, thereby the corrosion resistance of reaction cup 6 has been improved, the device collects the blood sampling, add reagent and react in an organic whole, and is simple and convenient to operate, the inspection efficiency is greatly improved and the cost is reduced.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims (6)

1. The utility model provides a bedside short-term test glycated hemoglobin's parallel arrangement, includes first reagent room (3), connecting pipe (5), reaction cup (6) and second reagent room (11), its characterized in that: the reaction cup is characterized in that a capillary tube (8) is installed at the bottom end of the reaction cup (6), a second hole (9) is formed in the bottom end of the capillary tube (8), heating blocks (16) are installed at two ends of the interior of the reaction cup (6), a temperature sensor (7) is installed at the bottom end of the interior of the reaction cup (6), a polyethylene anticorrosive layer (21) is arranged on the inner side wall of the reaction cup (6), a carbon fiber reinforced layer (22) is arranged on one side, close to the polyethylene anticorrosive layer (21), of the inner side wall of the reaction cup (6), a third hole (15) is formed in the top end of one side of the reaction cup (6), a time control relay (18) is installed at the bottom end of one side of the reaction cup (6), a connecting tube (5) is installed at the top end of the connecting tube (5), and a first reagent chamber (3) and a second reagent chamber (11) are installed at, the bottom end of the first reagent chamber (3) is connected with one end of a connecting pipe (5) through a first hole channel (4), the bottom end of the second reagent chamber (11) is connected with the other end of the connecting pipe (5) through a fourth hole channel (17), a first piston (2) is transversely installed inside the first reagent chamber (3), a first push rod (1) is fixed at the top end of the first piston (2), a second piston (12) is transversely installed inside the second reagent chamber (11), a lifting mechanism (10) is installed at the top end of the second piston (12), a control panel (14) is installed on one side of the second reagent chamber (11), a single chip microcomputer (13) is installed inside the control panel (14), the output end of the temperature sensor (7) is electrically connected with the input end of the single chip microcomputer (13) through a wire, and the output end of the single chip microcomputer (13) is electrically connected with the input end of a time control relay (18) through a wire, the output end of the time control relay (18) is electrically connected with the input end of the heating block (16) through a lead, and the output end of the single chip microcomputer (13) is electrically connected with the input end of the driving motor (101).
2. The parallel device for bedside rapid detection of glycated hemoglobin of claim 1, wherein: and scale marks are uniformly arranged on one sides of the first reagent chamber (3) and the second reagent chamber (11).
3. The parallel device for bedside rapid detection of glycated hemoglobin of claim 1, wherein: the inside bottom in first pore (4) and fourth pore (17) all is provided with reservation groove (19), and the top of connecting pipe (5) all is provided with reservation piece (20) of mutually supporting with reservation groove (19) to connecting pipe (5) are "Y" type structure, and the aperture of first pore (4) and fourth pore (17) is 1.5mm simultaneously, evenly be provided with the internal thread on the inside wall of reservation groove (19), evenly be provided with the external screw thread of mutually supporting with the internal thread on the lateral wall of reservation piece (20).
4. The parallel device for bedside rapid detection of glycated hemoglobin of claim 1, wherein: elevating system (10) is from last to having set gradually driving motor (101), belt pulley mechanism (102), drive box (103), drive block (104), second push rod (105) and screw lead screw (106) down, the internally mounted of drive box (103) has belt pulley mechanism (102), and the one end at drive box (103) top installs driving motor (101), and the output of driving motor (101) is connected with belt pulley mechanism (102) through the pivot, and screw lead screw (106) are all installed through the pivot to the output of belt pulley mechanism (102) to all be provided with drive block (104) on screw lead screw (106), be fixed with second push rod (105) between drive block (104) simultaneously.
5. The parallel device for bedside rapid detection of glycated hemoglobin of claim 1, wherein: the number of the heating blocks (16) is two, and the heating blocks (16) are symmetrically distributed around the vertical center line of the reaction cup (6).
6. The parallel device for bedside rapid detection of glycated hemoglobin of claim 1, wherein: reinforcing ribs (23) are uniformly arranged inside the carbon fiber reinforcing layer (22), and the reinforcing ribs (23) are of T-shaped structures.
CN202020186993.7U 2020-02-20 2020-02-20 Parallel device for rapidly detecting glycosylated hemoglobin at bedside Active CN212060275U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113252400A (en) * 2021-05-13 2021-08-13 西安市红会医院 Cell suction device for biological immune cell detection

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113252400A (en) * 2021-05-13 2021-08-13 西安市红会医院 Cell suction device for biological immune cell detection

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