CN212048442U - Frozen embryo storage device resistant to low temperature of liquid nitrogen - Google Patents
Frozen embryo storage device resistant to low temperature of liquid nitrogen Download PDFInfo
- Publication number
- CN212048442U CN212048442U CN202020666194.XU CN202020666194U CN212048442U CN 212048442 U CN212048442 U CN 212048442U CN 202020666194 U CN202020666194 U CN 202020666194U CN 212048442 U CN212048442 U CN 212048442U
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- inner tube
- liquid nitrogen
- face
- push
- low temperature
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title claims abstract description 64
- 210000001161 mammalian embryo Anatomy 0.000 title claims abstract description 47
- 239000007788 liquid Substances 0.000 title claims abstract description 32
- 229910052757 nitrogen Inorganic materials 0.000 title claims abstract description 32
- 238000007789 sealing Methods 0.000 claims abstract description 39
- 230000001681 protective effect Effects 0.000 claims abstract description 14
- 238000009434 installation Methods 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 8
- 239000007924 injection Substances 0.000 claims description 8
- 210000002257 embryonic structure Anatomy 0.000 claims description 6
- 239000007850 fluorescent dye Substances 0.000 claims description 3
- 230000000994 depressogenic effect Effects 0.000 claims description 2
- 230000008014 freezing Effects 0.000 description 11
- 238000007710 freezing Methods 0.000 description 11
- 239000004576 sand Substances 0.000 description 8
- 230000000694 effects Effects 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000013020 embryo development Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 210000000276 neural tube Anatomy 0.000 description 2
- 241000405414 Rehmannia Species 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000002459 blastocyst Anatomy 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 210000003981 ectoderm Anatomy 0.000 description 1
- 210000001900 endoderm Anatomy 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 210000001647 gastrula Anatomy 0.000 description 1
- 210000001654 germ layer Anatomy 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 210000003750 lower gastrointestinal tract Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000002023 somite Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 description 1
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Abstract
The utility model provides a frozen embryo storage device resistant to low temperature of liquid nitrogen, which comprises a label box, a connecting rod, a through hole, a storage groove, a round hole, a protective sleeve, an inner tube, a rubber plug, a placing strip, a concave groove, a movable cavity and a flowing hole, wherein the label box is arranged on the upper side of the front end surface of a push-pull plate, a sealing block is arranged on the rear side of the push-pull plate and corresponds to the storage groove, the storage groove is arranged in the storage box, the flowing hole is arranged between the storage groove and the storage groove, the round hole is internally provided with the inner tube in a meshing manner, the rubber plug is arranged in the inner tube, the placing strip is arranged on the front end surface of the rubber plug, the concave groove is arranged on the upper end surface of the placing strip, the protective sleeve is arranged on the front side of the inner tube, the movable cavity is symmetrically arranged, the utility model discloses rational in infrastructure, facilitate the use, be convenient for adjust, the practicality is strong.
Description
Technical Field
The utility model belongs to the technical field of biology, a freezing embryo storage technology is related to, specifically is a cryogenic freezing embryo storage device of liquid nitrogen resistance.
Background
The embryo is a larva within the first two months of pregnancy. Blastocyst, early development of embryo, and embryonic development are a continuous process. In somite phase, all three germ layers are changed. The ectoderm is recessed into a groove in the midline of the back, called the sulcus, and the two sides of the groove are called the ridges. The nerve ridges gradually approach and heal, resulting in the nerve evolving into a neural canal that runs through the embryo body. The neural canal and the neural ridge evolve into the nervous system in the future. The endoderm curls into a tube with the embryo body, and is called the primitive gut, which is divided into foregut, midgut and hindgut by location. With the development of science and technology, embryo freezing technology is gradually emerging, and the method for freezing embryos can be used for preserving fertility of prepared rehmannia roots. The embryo obtained by the test tube culture technology is stored in a liquid nitrogen environment at the temperature of 196 ℃ below zero for a long time.
Present liquid nitrogen resistant low temperature freezing embryo storage device uses inconveniently, and embryo need use embryo cryovial in the storage process, but most embryo cryovial is nonadjustable, uses comparatively inconveniently, freezes the embryo storage back in addition, when needs take, need take out embryo cryovial from the hold up tank with embryo cryovial, and it is comparatively inconvenient to take, for this reason, we propose a liquid nitrogen resistant low temperature freezing embryo storage device.
SUMMERY OF THE UTILITY MODEL
Not enough to prior art exists, the utility model aims at providing a cryogenic freezing embryo storage device of resistant liquid nitrogen to solve the problem that proposes in the above-mentioned background art, the utility model discloses rational in infrastructure, facilitate the use, be convenient for adjust, the practicality is strong.
The purpose of the utility model can be realized by the following technical scheme: a frozen embryo storage device resistant to low temperature of liquid nitrogen comprises a storage box, a push-pull plate and handles, wherein a splicing groove is formed in the upper end face of the storage box, a splicing rod is arranged on the lower end face of the storage box, the push-pull plate is arranged on the front side of the storage box, the handles are symmetrically arranged on the left side and the right side of the front end face of the push-pull plate, a label box is arranged on the upper side of the front end face of the push-pull plate, and a sealing block is arranged on the rear side;
the bin is inside to have seted up the hold up tank, sealed lid is installed to the hold up tank rear side, has seted up the flow hole between hold up tank and the hold up tank, the inside installation piece of having placed of hold up tank, the round hole has been seted up to the installation piece inside, installation piece rear side is fixed with the ring of taking, the inside meshing of round hole has the inner tube, inner tube internally mounted has the rubber buffer, the terminal surface is installed before the rubber buffer and is placed the strip, place a up end and seted up the depressed groove, the inner tube front side cover is equipped with protective casing, the inside left and right sides symmetry of bin has seted up movable chamber, movable chamber front side has seted up the through-hole, movable chamber internally mounted has the connecting rod, the connecting rod front side passes the through-hole and is connected with push-pull.
Furthermore, a limiting block is fixed on the rear end face of the connecting rod, and the diameter of the limiting block is larger than the aperture of the through hole.
Further, a transparent observation window is arranged on the upper side of the annular side face of the protective sleeve.
Further, the inner tube rear end face is embedded with first magnet piece, round hole internally mounted has the second magnet piece, and the second magnet piece attracts mutually with first magnet piece, inner tube and round hole phase-match.
Further, the inner tube is clearance fit with the protection casing, the outer surface of the handle is wrapped with an anti-skidding soft rubber sleeve, and a fluorescent label is arranged inside the label box.
Further, the rubber sealing strip is installed to the lag pipe inner wall, the inner tube annular side is provided with sealed sand grip, and the recess that forms between sealed sand grip and the sealed sand grip matches with the rubber sealing strip.
Furthermore, a sealing strip block is installed on the rear end face of the push-pull plate, a sealing strip groove is formed in the front end face of the storage box, and the sealing strip groove is matched with the sealing strip block.
Further, the sealing block is matched with the storage tank, a groove is formed in the sealing block, and a sealing plug is installed inside the injection opening.
The utility model has the advantages that: the utility model discloses a cryogenic freezing embryo storage device of resistant liquid nitrogen, because of the utility model discloses add the hold up tank, the round hole, protective casing, the inner tube, the rubber buffer, place the strip, recessed groove and installation piece, place freezing embryo in the recessed groove, thereby adjust the length of placing the strip through the inside removal of rubber buffer including the rubber buffer, through recess and the rubber seal strip looks lock that forms between sealed sand grip and the sealed sand grip, protective casing suit is in the inner tube outside, inhale mutually through first magnet piece and second magnet piece, the adsorbable fixed round hole of placing in installation piece of inner tube, protective casing ring side upside is provided with the transparent observation window and can observe the storage condition of freezing embryo, the convenient length of adjusting embryo cryovial of this design.
Because of the utility model discloses add connecting rod, through-hole, activity chamber and sealed piece, the push-and-pull board promotes backward, and during the connecting rod got into the activity chamber through the through-hole, through sealed piece embedding to the hold up tank in with sealed strip piece embedding to sealed strip groove, can realize the sealed storage of hold up tank.
Because of the utility model discloses having added filling opening and mobile hole, having taken out the inside sealing plug of filling opening, the external instrument that leaks hopper-shaped is placed in the filling opening, and the liquid nitrogen can be in the hold up tank through the filling opening injection, has seted up mobile hole between hold up tank and the hold up tank, and liquid nitrogen accessible mobile hole gets into in a plurality of hold up tanks.
Because of the utility model discloses having added sealed lid and having held the ring, having opened the hold up tank through the sealed lid of bin rear side, medical personnel can shift out the installation piece of placing in independent hold up tank through holding the ring, can take out the freezing embryo of storing, and this design only needs open single independent storage area when the embryo takes out, guarantees relatively clean space, avoids polluting.
Because of the connecting rod rear end face is fixed with the stopper, the stopper is interference fit with the through-hole, avoid the connecting rod to drop from the activity intracavity, be provided with transparent observation window because of protection casing ring side upside, conveniently look over the condition of embryo, because of the inner tube rear end face is embedded to have first magnet piece, round hole internally mounted has the second magnet piece, and the second magnet piece is inhaled with first magnet piece mutually, inner tube and round hole phase-match, make things convenient for the inner tube to adsorb and fix to the round hole in, because of handle surface parcel has anti-skidding flexible rubber sleeve, increase the use comfort level of handle, because of the inside fluorescence mark tablet that installs of label box, use under convenient differentiation and the dim condition.
Because of the push-and-pull board rear end face installs sealed strip piece, sealed strip groove has been seted up to the terminal surface before the bin, and sealed strip groove and sealed strip piece phase-match, make things convenient for the push-and-pull board to laminate with the bin is sealed, because of sealed piece matches with the hold up tank, make things convenient for sealed piece to imbed to the hold up tank in, because of sealed piece is inside to have seted up flutedly, make things convenient for placing of inner tube, because of filling opening internally mounted has the sealing plug, make things convenient for the pouring into of liquid nitrogen, the utility model discloses rational in infrastructure, facilitate.
Drawings
In order to facilitate understanding for those skilled in the art, the present invention will be further described with reference to the accompanying drawings.
FIG. 1 is a schematic view of the overall structure of a frozen embryo storage device of the present invention resistant to low temperatures of liquid nitrogen;
FIG. 2 is an expanded view of the frozen embryo storage device of the present invention that is resistant to cryogenic temperatures in liquid nitrogen;
FIG. 3 is an elevational, cross-sectional view A-A1 of FIG. 2;
FIG. 4 is a top view of a push-pull plate of a frozen embryo storage device that is resistant to cryogenic temperatures in liquid nitrogen in accordance with the present invention;
FIG. 5 is a perspective view of the inner tube of a frozen embryo storage device of the present invention that is resistant to cryogenic temperatures in liquid nitrogen;
FIG. 6 is a cross-sectional view of the inner tube of a frozen embryo storage device of the present invention that is resistant to cryogenic temperatures from liquid nitrogen;
FIG. 7 is an enlarged view at B in FIG. 6;
FIG. 8 is a perspective view of a connecting rod of a frozen embryo storage device of the present invention that is resistant to cryogenic temperatures in liquid nitrogen;
FIG. 9 is a rear view of a frozen embryo storage device of the present invention that is resistant to cryogenic temperatures from liquid nitrogen;
FIG. 10 is a top cross-sectional view of a frozen embryo storage device of the present invention that is resistant to cryogenic temperatures of liquid nitrogen;
in the figure: 1-a storage tank; 2-splicing grooves; 3-splicing rods; 4, a push-pull plate; 5-handle; 6-a label box; 7-a connecting rod; 71-a limiting block; 8-a through hole; 9-a storage tank; 10-a circular hole; 101-a second magnet piece; 11-protective sleeves; 111-a transparent viewing window; 112-rubber sealing strips; 12-an inner tube; 121-a first magnet piece; 122-sealing ribs; 13-rubber plug; 14-placing the strips; 15-a concave groove; 16-a movable cavity; 17-a sealing block; 171-a groove; 18-a sealing cover; 19-injection port; 20-mounting a block; 21-holding ring; 22-flow hole.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
As shown in fig. 1-10, the frozen embryo storage device resistant to low temperature of liquid nitrogen comprises a storage box 1, a push-pull plate 4 and a handle 5, wherein a splicing groove 2 is formed in the upper end surface of the storage box 1, a splicing rod 3 is installed on the lower end surface of the storage box 1, the push-pull plate 4 is installed on the front side of the storage box 1, the handles 5 are symmetrically installed on the left side and the right side of the front end surface of the push-pull plate 4, a label box 6 is installed on the upper side of the front end surface of the push-pull plate 4, and a sealing block 17 is;
The utility model discloses when specifically implementing: firstly, the rubber plug 13 is plugged into the inner tube 12, the placing strip 14 is adjusted to a proper position, then the frozen embryo is placed in the concave groove 15 inside the placing strip 14, the protecting sleeve 11 is sleeved outside the inner tube 12 and is tightly combined with the rubber sealing strip 112 through a groove formed between the sealing convex strip 122 and the sealing convex strip 122, the protecting sleeve 11 and the inner tube 12 are sleeved and fixed, and an operator can check the condition of the embryo through the transparent observation window 111;
the circular hole 10 is matched with the inner pipe 12, the rear side of the inner pipe 12 is embedded into the circular hole 10 and is attracted with the second magnet piece 101 through the first magnet piece 121, the inner pipe 12 can be fixedly placed in the storage groove 9, meanwhile, the fluorescent label plate for recording embryo information is placed in the corresponding label box 6, after the embryo placement is finished, an operator pushes the push-pull plate 4 backwards, the connecting rod 7 enters the movable cavity 16 through the through hole 8, the sealing strip block on the rear side of the push-pull plate 4 is clamped and attached with the sealing strip groove, and the sealing block 17 is embedded into the storage groove 9, so that the storage groove 9 can be sealed;
medical personnel take out the sealing plug inside the injection port 19, an external funnel-shaped tool is placed in the injection port 19, liquid nitrogen can be injected into the storage tank 9 through the injection port 19, a flow hole 22 is formed between the storage tank 9 and the storage tank 9, the liquid nitrogen can enter the plurality of storage tanks 9 through the flow hole 22, the splicing grooves 2 are formed in the upper end face of the storage tank 1, and the splicing rods 3 are installed on the lower end face of the storage tank 1, so that a plurality of groups of storage tanks 1 can be stacked;
when it is desired to take out the frozen embryo, the medical staff opens the desired storage tank 9 through the sealing cover 18, and the medical staff removes the mounting block 20 placed in the independent storage tank 9 by the holding ring 21, and then takes out the stored frozen embryo.
The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not exhaustive and do not limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.
Claims (8)
1. The frozen embryo storage device resistant to low temperature of liquid nitrogen is characterized by comprising a storage box (1), a push-pull plate (4) and a handle (5), wherein a splicing groove (2) is formed in the upper end face of the storage box (1), a splicing rod (3) is installed on the lower end face of the storage box (1), the push-pull plate (4) is installed on the front side of the storage box (1), the handles (5) are symmetrically installed on the left side and the right side of the front end face of the push-pull plate (4), a label box (6) is installed on the upper side of the front end face of the push-pull plate (4)0, and a sealing block (17) is correspondingly installed on the rear side of the push-pull;
storage tank (9) has been seted up inside bin (1), sealed lid (18) have been installed to storage tank (9) rear side, have seted up between storage tank (9) and storage tank (9) mobile hole (22), installation piece (20) have been placed to storage tank (9) inside, round hole (10) have been seted up to installation piece (20) inside, installation piece (20) rear side is fixed with holding ring (21), the inside meshing of round hole (10) has inner tube (12), inner tube (12) internally mounted has rubber buffer (13), rubber buffer (13) front end face is installed and is placed strip (14), it has seted up depressed groove (15) to place strip (14) up end, inner tube (12) front side cover is equipped with protective casing (11), movable chamber (16) have been seted up to the inside left and right sides symmetry of bin (1), through-hole (8) have been seted up to movable chamber (16) front side, the movable cavity (16) is internally provided with a connecting rod (7), the front side of the connecting rod (7) penetrates through the through hole (8) to be connected with the rear end face of the push-pull plate (4), and the upper end face of the storage box (1) is provided with an injection port (19).
2. The frozen embryo storage device resisting low temperature of liquid nitrogen as claimed in claim 1, wherein the rear end face of the connecting rod (7) is fixed with a limiting block (71), and the diameter of the limiting block (71) is larger than the aperture of the through hole (8).
3. The device for storing frozen embryos resistant to low temperature in liquid nitrogen according to claim 1, wherein the upper side of the annular side of the protective casing (11) is provided with a transparent viewing window (111).
4. The frozen embryo storage device with resistance to low temperature in liquid nitrogen as claimed in claim 1, wherein the inner tube (12) has a first magnet piece (121) embedded in the rear end face, the circular hole (10) has a second magnet piece (101) mounted inside, the second magnet piece (101) attracts the first magnet piece (121), and the inner tube (12) is matched with the circular hole (10).
5. The device for storing frozen embryos resistant to low temperature in liquid nitrogen as claimed in claim 1, wherein the inner tube (12) is in clearance fit with the protective sleeve (11), the outer surface of the handle (5) is wrapped with an anti-slip soft rubber sleeve, and the label box (6) is internally provided with a fluorescent label.
6. The device for storing frozen embryos resistant to low temperature in liquid nitrogen according to claim 1, wherein a rubber sealing strip (112) is installed on the inner wall of the protective casing (11), a sealing rib (122) is arranged on the annular side surface of the inner tube (12), and a groove (171) formed between the sealing rib (122) and the sealing rib (122) is matched with the rubber sealing strip (112).
7. The device for storing frozen embryos resistant to low temperature in liquid nitrogen according to claim 1, wherein a sealing strip block is installed on the rear end face of the push-pull plate (4), a sealing strip groove is formed on the front end face of the storage box (1), and the sealing strip groove is matched with the sealing strip block.
8. The device for storing frozen embryos resistant to low temperature of liquid nitrogen as claimed in claim 1, wherein the sealing block (17) is matched with the storage tank (9), the sealing block (17) is provided with a groove (171) inside, and the injection port (19) is provided with a sealing plug inside.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020666194.XU CN212048442U (en) | 2020-04-27 | 2020-04-27 | Frozen embryo storage device resistant to low temperature of liquid nitrogen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020666194.XU CN212048442U (en) | 2020-04-27 | 2020-04-27 | Frozen embryo storage device resistant to low temperature of liquid nitrogen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212048442U true CN212048442U (en) | 2020-12-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020666194.XU Expired - Fee Related CN212048442U (en) | 2020-04-27 | 2020-04-27 | Frozen embryo storage device resistant to low temperature of liquid nitrogen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212048442U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116326578A (en) * | 2023-05-29 | 2023-06-27 | 山东中医药大学附属医院 | Neurosurgery tissue sample preservation device |
-
2020
- 2020-04-27 CN CN202020666194.XU patent/CN212048442U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116326578A (en) * | 2023-05-29 | 2023-06-27 | 山东中医药大学附属医院 | Neurosurgery tissue sample preservation device |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201201 |