CN211962595U - Novel acupuncture needle decorated by photo-thermal material - Google Patents
Novel acupuncture needle decorated by photo-thermal material Download PDFInfo
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- CN211962595U CN211962595U CN201920967458.2U CN201920967458U CN211962595U CN 211962595 U CN211962595 U CN 211962595U CN 201920967458 U CN201920967458 U CN 201920967458U CN 211962595 U CN211962595 U CN 211962595U
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Abstract
The utility model discloses a novel acupuncture needle that light and heat material was decorated, including the needle body, the needle body includes the needle bar and sets up needle handle and needle point at its both ends respectively, there is infrared generating device needle handle top through transmission fiber connection, the needle body surface modification has the light and heat material, the light and heat material is polyurethane or porous zinc oxide or gold nanorod or black phosphorus nanometer piece. The novel acupuncture needle of the utility model can be heated to 38.8-40.2 ℃ within 5-12 minutes and is relatively stably maintained at the temperature, and has the dual functions of traditional acupuncture and photo-thermal treatment.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a novel acupuncture needle modified by a photo-thermal material.
Background
The existing warm acupuncture has two forms, one is that acupuncture and moxibustion are combined, moxa sticks or other medicinal materials are wrapped on a needle handle, and heat energy generated by burning moxa balls on the needle handle is transferred to a needle body in a body to play a role in thermotherapy, and the defects of the existing acupuncture are that the temperature is not easy to control, a stainless steel needle body is not easy to transfer heat, and the skin is easy to burn; the other method is that an internal heating silver needle heating instrument is used for heating the silver needle, and the high heat conductivity of the silver is utilized to transfer heat, so that the thermal therapy effect is exerted.
Disclosure of Invention
In view of the above-mentioned disadvantages of the prior art, the present invention provides a novel acupuncture needle heated by infrared rays, which is decorated with safe photothermal materials, rapidly heated, and maintained at a relatively stable temperature in the body.
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a novel acupuncture needle that light and heat material was decorated, includes the needle body, the needle body includes the needle bar and sets up needle handle and needle point at its both ends respectively, the needle handle top is connected with infrared generating device through transmission fiber, the needle body surface modification has the light and heat material, the light and heat material is porous zinc oxide or gold nanorod or black phosphorus nanometer piece or polyurethane.
Preferably, the photothermal material is modified on the surface of the needle body by surface adsorption or surface deposition.
Preferably, the photo-thermal material is modified on the surface of the needle body by a coupling agent method or an esterification reaction method.
Further, the infrared generating device is a semiconductor laser.
Furthermore, the needle handle, the needle rod and the needle point are connected in a solid integrated manner.
Further, the transmission optical fiber is one of a plastic optical fiber, a multimode optical fiber and a glass optical fiber.
Different from the prior art, the invention has the beneficial effects that: (1) in an in vitro experiment, infrared rays are emitted by an infrared generating device to irradiate the surface of the acupuncture needle, a photo-thermal material responds to the infrared rays to heat up and generate heat, the photo-thermal material is polyurethane or porous zinc oxide or a gold nanorod or a black phosphorus nanosheet, and can heat up to 38.8-40.2 ℃ within 5-12 minutes and relatively stably maintain the temperature; (2) the photothermal generation device can select a small semiconductor infrared laser, is convenient to carry, and has the dual functions of traditional acupuncture and infrared photothermal acupuncture treatment.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of part A of the present invention;
FIG. 3 is a temperature of a near infrared camera of the present invention in which a needle body is modified with porous zinc oxide;
FIG. 4 shows the temperature of the near infrared camera with gold nanorods, black phosphor nanosheets, and polyurethane respectively modified by the needle body of the present invention;
FIG. 5 is an electron micrograph of a polyurethane of the present invention;
FIG. 6 is an electron micrograph of porous zinc oxide of the present invention;
FIG. 7 is an electron micrograph of gold nanorods of the present invention;
FIG. 8 is an electron micrograph of a black phosphorus nanoplate of the present invention;
FIG. 9 is a graph showing the toxicity test of the polyurethane in example 1 of the present invention;
FIG. 10 is a graph showing toxicity tests of porous zinc oxide in example 2 of the present invention;
in the figure: 1. an infrared generating device; 2. a transmission optical fiber; 3. a needle handle; 4. a needle bar; 5. a photothermal material; 6. a needle tip.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
Example 1: as shown in fig. 1-2, 3, 6 and 10, a novel acupuncture needle decorated by photo-thermal material comprises a needle body, wherein the needle body comprises a needle rod 4, a needle handle 3 and a needle point 6 which are respectively arranged at two ends of the needle body, the top end of the needle handle 3 is connected with an infrared generating device 1 through a transmission optical fiber 2, the surface of the needle body is decorated by photo-thermal material 5, and the photo-thermal material 5 is porous zinc oxide.
Preferably, the porous zinc oxide is modified on the surface of the needle body through surface adsorption or surface deposition.
Further, the infrared generating device 1 is a semiconductor laser; the needle handle 3, the needle rod 4 and the needle point 6 are connected in a solid and integrated manner; the transmission optical fiber 2 is a plastic optical fiber.
In this example, the porous zinc oxide synthesis step:
A. weighing 1.4875g Zn (NO)3)2·6H2Dissolving O, 0.350465g hexamethylene tetramine in 100ml deionized water, sealing and stirring for 10min, and carrying out water bath at 65 ℃ for 15 min;
B. adding 0.14g of sodium citrate, 0.1g of hydroxypropyl methyl cellulose, 0.1g of active carbon and 0.1g of lignin, and dissolving in water at 85 ℃ for 10 hours;
C. washing with anhydrous ethanol for 2 times, and centrifuging at 7000r/min for 10 min; washing with deionized water for 2 times, and centrifuging at 7000r/min for 10 min;
D. pre-freezing for 6h at minus 80 ℃, and freeze-drying for 12h to obtain the porous zinc oxide.
The synthetic zinc oxide is shot by a scanning electron microscope, is determined to be a substance with a porous structure, is modified on the surface of a needle body through surface adsorption or surface deposition, and is subjected to an infrared heating research experiment, the porous zinc oxide material is found to respond to infrared rays to heat up and heat up to 38.8-40.2 ℃ within 9-12 minutes and is relatively and stably maintained at the temperature, and in order to judge whether the zinc oxide can be used for biomedical application, a cytotoxicity compatibility experiment is also performed on the zinc oxide material, and the result shows that the biocompatibility of the zinc oxide is good.
Example 2: as shown in fig. 1-2, 4, and 7, a novel acupuncture needle decorated by photo-thermal material, comprising a needle body, wherein the needle body comprises a needle rod 4, and a needle handle 3 and a needle point 6 respectively arranged at two ends of the needle body, the top end of the needle handle 3 is connected with an infrared generating device 1 through a transmission optical fiber 2, the surface of the needle body is decorated by photo-thermal material 5, and the photo-thermal material 5 is a gold nanorod.
Preferably, the gold nanorods are modified on the surface of the needle body through surface adsorption or surface deposition.
Further, the infrared generating device 1 is a semiconductor laser; the needle handle 3, the needle rod 4 and the needle point 6 are connected in a solid and integrated manner; the transmission fiber 2 is a multimode fiber.
In this example, the gold nanorods were synthesized by the following steps:
A. 5mL of a 0.2M CTAB solution with 2.5mL of deionized water and 2.5mL of 0.001M HAuCl4Mixing under continuous stirring;
B. 0.6mL of 0.01M ice-cold sodium borohydride was added dropwise with continuous stirring until a brown-yellow solution was formed;
C. after stirring the solution at 28 ℃ for 2 minutes, a seed solution is prepared, which must be used between 2 and 5 hours;
D. 50mL of 0.2M CTAB was added to 1mL of 0.01M AgNO at 28 deg.C3To the solution, then gently mixed and added dropwise 50mL of 0.001M HAuCl4And 0.8mL of 0.1M ascorbic acid until the growth solution changed color from dark yellow to colorless to give a growth solution;
E. finally, 200. mu.L of seed solution was added, the growth solution was kept under constant stirring at 28 ℃ overnight, and gold nanorods were prepared by collection by centrifugation at 11000r/min for 30 minutes.
Scanning electron microscope shooting is carried out on the synthesized gold nanorods, the synthesized gold nanorods are determined to be substances with rod-shaped structures, then the substances are modified on the surface of a needle body through surface adsorption or surface deposition, and then an infrared heating exploration experiment is carried out on the substances, and the gold nanorods respond to infrared rays to heat up and generate heat and can be heated up to 38.8-40.2 ℃ within 5-12 minutes, and are relatively and stably maintained at the temperature.
Example 3: as shown in fig. 1-2, 4 and 8, the novel acupuncture needle decorated by photo-thermal materials comprises a needle body, wherein the needle body comprises a needle rod 4, a needle handle 3 and a needle point 6, the needle handle 3 and the needle point 6 are respectively arranged at two ends of the needle body, the top end of the needle handle 3 is connected with an infrared generating device 1 through a transmission optical fiber 2, the surface of the needle body is decorated by photo-thermal materials 5, and the photo-thermal materials 5 are black phosphorus nanosheets.
Preferably, the black phosphorus nanosheet is modified to the surface of the needle body by a coupling agent method or an esterification reaction method.
Further, the infrared generating device 1 is a semiconductor laser; the needle handle 3, the needle rod 4 and the needle point 6 are connected in a solid and integrated manner; the transmission fiber 2 is a glass fiber.
In this embodiment, the synthesis of the black phosphorus nanosheet includes:
A. 20mg of BP powder was dissolved in 50ml of a saturated NaOH solution of N-methyl-2-pyrrolidone;
B. placing the mixed solution in an ice bath for soaking for 6 hours, and changing ice blocks once in half an hour;
C. placing the collected brown suspension in a centrifuge at 4000r/min, centrifuging for 8min, taking out residual non-peeled particles, and collecting supernatant liquid;
D. and storing the supernatant in a refrigerator at the temperature of minus 20 ℃ to obtain the black phosphorus nanosheet.
Scanning electron microscope shooting is carried out on the synthesized black phosphorus nanosheet, the black phosphorus nanosheet is determined to be a substance with a sheet structure, then the substance is modified on the surface of the needle body through a coupling agent method or an esterification reaction method, and then an infrared heating research experiment is carried out on the substance, and the black phosphorus nanosheet responds to infrared rays to heat up and heat up, can heat up to 38.8-40.2 ℃ within 5-12 minutes, and is relatively and stably maintained at the temperature.
Example 4: as shown in fig. 1-2, 4, 5, and 9, a novel acupuncture needle decorated with photo-thermal material comprises a needle body, wherein the needle body comprises a needle rod 4, a needle handle 3 and a needle point 6 respectively arranged at two ends of the needle body, the top end of the needle handle 3 is connected with an infrared generating device 1 through a transmission optical fiber 2, the surface of the needle body is decorated with photo-thermal material 5, and the photo-thermal material 5 is polyurethane.
Preferably, the polyurethane is modified on the surface of the needle body by surface adsorption.
Further, the infrared generating device 1 is a semiconductor laser; the needle handle 3, the needle rod 4 and the needle point 6 are connected in a solid and integrated manner; the transmission optical fiber 2 is a plastic optical fiber.
In this example, the polyurethane synthesis step:
A. in stannous octoate (Sn (Oct)2) PDLLA diol was synthesized by ring-opening polymerization of D, L-lactide in the presence of initiator and piperazine (PP) as co-initiator under vacuum at 150 ℃ for 24 hours;
B. co-precipitating and purifying the obtained polymer in chloroform and absolute ethyl alcohol at room temperature, and vacuum-drying the purified polymer at room temperature for 48 hours;
C. mixing Polyester Diol (PDLLA), 1, 6-Hexamethylene Diisocyanate (HDI), stannous octoate (Sn (Oct)2) Adding anhydrous toluene into a 250mL three-neck round-bottom flask provided with a magnetic stirrer, and reacting at 75 ℃ for 3 hours to obtain a prepolymer;
D. piperazine (PP) dissolved in isopropanol was slowly added to the reaction system, chain extended at 30 ℃ for 2 hours, polyurethane was purified by co-precipitation with toluene/ethanol, and vacuum dried at room temperature for 48 hours.
1, 6-Hexamethylene Diisocyanate (HDI): the crosslinking ratio of piperazine (PP) is 1:1.5: 0.5.
The synthetic polyurethane is shot by a scanning electron microscope, is determined to be a substance with a porous structure, then the synthetic intermediate polyester diol and the synthetic intermediate polyurethane are tested by Fourier infrared, nuclear magnetic resonance, X-ray diffraction, X-ray photoelectron spectroscopy, Raman spectroscopy and the like, the synthetic intermediate polyester diol and the synthetic intermediate polyurethane are proved to have different structures and certain viscosity by adjusting the ratio of crosslinking, and then the synthetic intermediate polyester diol and the synthetic intermediate polyurethane are smeared on the surface of a needle body and adsorbed on the surface of the needle body to be subjected to an infrared heating research experiment, so that the polyurethane is found to have a particularly good heating effect and stable temperature rise, and can be heated to 38.8-40.2 ℃ within 8-10 minutes. In order to judge whether the polyurethane can be used for biomedical application, a cytotoxicity compatibility experiment is carried out on the polyurethane, and the result shows that the biocompatibility of the polyurethane is good.
The working principle is as follows: according to the invention, through the external infrared generating device 1, electric energy is converted into light energy and infrared beams are generated, the light beams irradiate the photo-thermal material 5 modified on the surface of the needle body, the photo-thermal material 5 is polyurethane or porous zinc oxide or gold nanorods or black phosphorus nanosheets, the photo-thermal material 5 and the near infrared beams can generate violent resonance effect, can be heated to 38.8-40.2 ℃ within 5-12 minutes and is maintained at a relatively stable temperature, so that the heating performance of the acupuncture needle can be improved to the maximum extent, the permeability, the durability and the stability of heat energy in the tissue can be improved, the heat energy action strength of the novel acupuncture needle is not only favorable for the capillary vessel expansion of surface tissues and the blood circulation promotion, but also can strengthen the metabolism between deep fascia tissues and improve the regeneration capacity of muscles and fascia, improving the immunity of the organism and regulating the mental abnormal excitation state, thereby having better medical care effect than the traditional acupuncture and moxibustion technology.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (6)
1. The utility model provides a novel acupuncture needle that light and heat material was decorated, includes the needle body, the needle body includes needle bar (4) and sets up needle handle (3) and needle point (6) at its both ends respectively, its characterized in that: the needle comprises a needle handle (3) and is characterized in that the top end of the needle handle (3) is connected with an infrared generating device (1) through a transmission optical fiber (2), the surface of a needle body is modified with a photo-thermal material (5), and the photo-thermal material (5) is porous zinc oxide or a gold nanorod or a black phosphorus nanosheet or polyurethane.
2. The new acupuncture needle modified by photothermal material according to claim 1, wherein: the photo-thermal material (5) is modified on the surface of the needle body through surface adsorption or surface deposition.
3. The new acupuncture needle modified by photothermal material according to claim 1, wherein: the photo-thermal material (5) is modified on the surface of the needle body through a coupling agent method or an esterification reaction method.
4. The new acupuncture needle modified by photothermal material according to claim 1, wherein: the infrared generating device (1) is a semiconductor laser.
5. The new acupuncture needle modified by photothermal material according to claim 1, wherein: the needle handle (3), the needle rod (4) and the needle point (6) are connected in a solid integrated manner.
6. The new acupuncture needle modified by photothermal material according to claim 1, wherein: the transmission optical fiber (2) is one of a plastic optical fiber, a multimode optical fiber and a glass optical fiber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920967458.2U CN211962595U (en) | 2019-06-25 | 2019-06-25 | Novel acupuncture needle decorated by photo-thermal material |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920967458.2U CN211962595U (en) | 2019-06-25 | 2019-06-25 | Novel acupuncture needle decorated by photo-thermal material |
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| CN211962595U true CN211962595U (en) | 2020-11-20 |
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| CN201920967458.2U Expired - Fee Related CN211962595U (en) | 2019-06-25 | 2019-06-25 | Novel acupuncture needle decorated by photo-thermal material |
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- 2019-06-25 CN CN201920967458.2U patent/CN211962595U/en not_active Expired - Fee Related
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Granted publication date: 20201120 Termination date: 20210625 |