CN211955225U

CN211955225U - Enzyme method color detection structure

Info

Publication number: CN211955225U
Application number: CN201922314375.6U
Authority: CN
Inventors: 梁波; 叶学松; 崔晨晨
Original assignee: Honghe Innovation Technology Research Institute; Shandong Xianyi Medical Technology Co ltd; Shandong Industrial Technology Research Institute of ZJU
Current assignee: Honghe innovation and Technology Research Institute Co.,Ltd.; SHANDONG XIANYI MEDICAL TECHNOLOGY Co.,Ltd.; Shandong Industrial Technology Research Institute of ZJU
Priority date: 2019-12-20
Filing date: 2019-12-20
Publication date: 2020-11-17
Anticipated expiration: 2029-12-20

Abstract

The utility model discloses an enzyme process colour detects structure, evenly set up in the middle of the enzyme process colour detects the structure bottom and be provided with LED printing opacity groove 102 according to waiting photodiode receiving part 101, the both sides that detect the project and set for quantity, enzyme process colour detects the structure top and has seted up test paper standing groove 103, and test paper standing groove below is provided with the reaction zone transmission hole 104 that corresponds with the photodiode receiving hole, LED printing opacity groove is provided with the through passage with the reaction zone transmission hole. The utility model discloses reduced reflection LED light source LED quantity, reduced the consumption of instrument through the design of structure.

Description

Enzyme method color detection structure

Technical Field

The utility model belongs to the technical field of medical instrument, concretely relates to enzyme process colour detects structure.

Background

Point-Of-Care Testing (POCT), refers to clinical Testing and bedside Testing performed near a patient, and this Testing method saves complex laboratory procedures and is convenient and fast. Because POCT diagnosis products are small, the operation is simple, and accurate results can be obtained without professional medical staff, so that the detection mode is very suitable for families.

At present, the indexes of blood fat, creatinine, blood ketone body and the like are detected by adopting a reflectance photometry method. The corresponding detection enzyme and the substance to be detected generate chemical reaction, hydrogen peroxide is generated after the reaction, and the color is developed when the hydrogen peroxide is combined with the color developing agent. And judging the concentration of the substance to be detected by judging the color depth of the color development layer. Along with the gradual increase of the concentration of the substance to be detected, the color gradually becomes darker from light, and then the content of a certain index in the blood can be judged. Therefore, the color detection structure is the key for determining whether the detection result is accurate.

In enzyme method colour detection structure on the current market, adopt LED light source and photodiode to arrange in proper order from top to bottom more, for example the detection structure of four detection holes, the arrangement is: LED-photodiode-LED, so that 4 detection holes require 5 LED lamps. The LED lamp (general medical detection light is red light) emits light with specific wavelength to the color development area of the test strip, the color of the color development area can absorb the light on the surface, the rest light can be reflected to the photodiode for detection, and the beer Lambert absorption law shows that the absorbance is in direct proportion to the concentration of a substance, so that the higher the concentration of the substance is, the smaller the reflected light intensity is, the smaller the light intensity received by the photodiode is, and the smaller the output current is. Therefore, the intensity of the light source detected by the enzyme method cannot be too low, otherwise, the reflected light intensity is very weak, the current output by the photodiode is very small, generally nA, and the photodiode itself has dark current, generally pA, which causes unsatisfactory detection result, even impossible detection, so that the common red LED cannot be used as the light source, the minimum power of the generally brighter red LED (620nm-630nm) is 0.2W, and the power consumption of 5 LEDs is 1W.

Meanwhile, in the existing arrangement mode of LED-photodiode-LED, because the LED lamp exists in the middle of the photodiode, and the light source emission needs a certain emission angle, the distance between two detection holes cannot be too close. For example: blood lipid detection has to detect three indexes: total Cholesterol (CT), high density lipoprotein cholesterol (HDL), and Triglyceride (TG), so three detection holes are needed for detection, and the current test strip for detecting blood lipid generally adopts a chromatographic method for detection, namely: drop the blood of sufficient volume in the middle of test paper strip, then through the enzyme reaction district of guiding gutter cooperation corresponding reagent with middle blood distribution to both sides, have partly to remain in the guiding gutter at the in-process of blood water conservancy diversion, if the volume of taking a blood is not enough, can cause to reach both sides enzyme reaction district blood volume not enough or even can't reach, lead to the measuring result inaccurate. The length of the diversion trench between the detection holes can influence the amount of blood collected, and the amount of blood collected by the existing detection instrument is relatively large.

In addition, for the accuracy and the uniformity of the detection result, the detection test paper and the clamping groove need to be tightly attached for detection, the test paper of the current blood fat detector is in surface contact with the bottom surface of the clamping groove, so that the test paper needs to be greatly stressed when being inserted into the clamping groove, a certain gap is needed between the test paper and the clamping groove, and the position of the test paper inserted at each time can have slight deviation.

SUMMERY OF THE UTILITY MODEL

To the problem that exists above, the utility model is used for a provide an enzyme method colour detects structure.

In order to solve the technical problem, the utility model discloses a following technical scheme:

the middle of the bottom of the enzymatic color detection structure is uniformly provided with photodiode receiving parts with set quantity according to items to be detected, LED light transmission grooves are arranged on two sides of the enzymatic color detection structure, the top of the enzymatic color detection structure is provided with a detection test paper placing groove, a reaction area transmission hole corresponding to the photodiode receiving hole is arranged below the detection test paper placing groove, and a through passage is formed between the LED light transmission groove and the reaction area transmission hole.

Preferably, the detection test paper placing groove is provided with a guide rail groove for ensuring that the detection test paper is fixedly attached to the detection test paper placing groove.

Preferably, the enzymatic color detection structure is integrally formed.

Preferably, the photodiode receiving hole portion is a trumpet-shaped through hole with a small top and a wide bottom.

Preferably, screw fixing holes fixedly connected with the detection PCB are formed in four corners of the bottom of the enzymatic color detection structure.

Preferably, the photodiode receiving portion is located right above a photodiode arranged on the fixedly connected detection PCB.

Preferably, the LED light-transmitting groove is positioned above the LED arranged on the fixedly connected detection PCB.

Adopt the utility model discloses following beneficial effect has:

(1) compared with the arrangement mode of LED-photodiode-LED, the arrangement mode of the LED-photodiode-LED needs 5 LED lamps, the color detection structure of the enzyme method places the LED lamps at two sides of the photodiode, only 4 SMD LEDs with package sizes of 5730 are needed as reflection light sources, the quantity of the reflection LED light sources is reduced, the total power is only 0.8W, and the power consumption of the instrument is reduced through the structure design;

(2) the LED reflection light sources can be arranged on two sides of the photodiode through the structure of the utility model, therefore, the distance between the detection holes is not influenced by the middle LED reflection light source any more, the length of the diversion trench between the detection holes can be shortened, and the blood sampling amount is reduced;

(3) the utility model discloses increased the guide rail groove in the slot of test paper strip, consequently the test paper strip along this guide rail groove can be easier insert the draw-in groove in, guaranteed the uniformity of the test paper strip position of inserting in the draw-in groove at every turn simultaneously.

Drawings

Fig. 1 is a schematic bottom structure diagram of an enzymatic detection structure according to an embodiment of the present invention;

fig. 2 is a schematic top structure diagram of an enzymatic detection structure according to an embodiment of the present invention;

fig. 3 is a schematic diagram of a transverse cross-sectional structure of an enzymatic detection structure according to an embodiment of the present invention;

fig. 4 is a schematic longitudinal sectional structure diagram of an enzymatic detection structure according to an embodiment of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, of the embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1 to 4, it is shown to be the utility model discloses the each direction structure sketch map of enzyme process detection structure, the utility model discloses an evenly set up in the middle of the enzyme process colour detection structure bottom according to waiting to detect photodiode receiving part 101, both sides that the project set for quantity are provided with LED light-transmitting groove 102, and test paper standing groove 103 has been seted up at enzyme process colour detection structure top, and test paper standing groove below is provided with the reaction zone transmission hole 104 that corresponds with the photodiode receiving hole, and LED light-transmitting groove and reaction zone transmission hole are provided with the through passage. The photodiode receiving part is positioned right above the photodiode arranged on the fixedly connected detection PCB. The LED light-transmitting groove is positioned above the LED arranged on the fixedly connected detection PCB. The use process of the enzymatic color detection structure is as follows: test paper inserts in the test paper standing groove, wait for the instrument to show and drip the blood indication, then add the blood sample to the blood dripping groove of test paper strip with blood taking needle and blood sampling stick, the LED lamp lights, judge whether there is blood to drip into, the instrument makes a sound after detecting blood adds, then a few seconds, the LED lamp lights again, the detected value of once getting, wait for 2 minutes, the LED lamp lights again, the detected value of once getting again, then get the difference with twice detected result after, the result that obtains can be brought into and mark the curve and obtain the testing result, finally show in the screen.

In a further preferred embodiment, the test strip placement groove is provided with a guide rail groove 105 for ensuring the attachment and fixation of the test strip and the test strip placement groove. Solves the problems that in the prior art, the test strip is difficult to be inserted into the clamping groove, and the position of inserting the test strip at each time has small deviation

In order to guarantee the uniformity of structure, the utility model discloses an enzyme method colour detects structure integrated into one piece. The error problem caused by adopting an assembly structure can be avoided.

In a further preferred embodiment, the photodiode receiving hole portion 101 is a trumpet-shaped through hole with a small top and a wide bottom. The reflected light can be received by the photodiode to the maximum extent, so that the output current signal of the photodiode is larger, and the design of a current-voltage conversion circuit behind the photodiode is facilitated.

In a further preferred embodiment, the enzyme method color detecting structure is provided with screw fixing holes 106 at four corners of the bottom thereof for fixedly connecting with the detecting PCB.

The utility model discloses a structure is not limited to single size and shape, through chooseing for use littleer photodiode and paster LED light source, can further reduce the distance between the exploration hole closely. But to give those skilled in the art a more intuitive understanding of the dimensional structure of the invention, an example of dimensions is given. The enzyme method color detection structure is a cuboid 31.55mm long, 18mm wide and 6.28mm high, 4 screw fixing holes are reserved around the bottom, the inner hexagonal screw of M2 is adopted for fixing, 4 color detection holes are located in the middle of the structure, the diameter of each detection hole is 1mm, and the distance between the detection holes is 5.28 mm. The LED light sources are positioned on two sides of the detection hole, the size of the emitting hole of each LED light source is 3.2mm, four 5730 packaged surface mounted LEDs are used as the reflecting light sources, and the maximum power consumption of each LED is 0.2W. The width of 1mm is left on the draw-in groove that inserts the test paper piece in the structure, and the degree of depth is 0.3 mm's guide rail groove, and the test paper strip only needs insert the test paper standing groove along this guide rail groove in, detects, and the uniformity of the position that the test paper strip inserted the test paper standing groove at every turn is better like this, has guaranteed measuring result's uniformity, and the test paper strip can insert the test paper standing groove along the recess track more easily simultaneously. The color detection used a photodiode at 620 nm.

It is to be understood that the exemplary embodiments described herein are illustrative and not restrictive. While one or more embodiments of the present invention have been illustrated in the accompanying drawings, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims

1. The enzymatic color detection structure is characterized in that photodiode receiving parts (101) with the set number according to items to be detected are uniformly arranged in the middle of the bottom of the enzymatic color detection structure, LED light-transmitting grooves (102) are arranged on two sides of the bottom of the enzymatic color detection structure, a detection test paper placing groove (103) is arranged at the top of the enzymatic color detection structure, reaction area transmission holes (104) corresponding to the photodiode receiving holes are arranged below the detection test paper placing groove, and a through passage is formed between the LED light-transmitting grooves and the reaction area transmission holes.

2. The enzymatic color detection structure of claim 1, wherein the test strip placement groove is provided with a guide rail groove (105) for ensuring the attachment and fixation of the test strip and the test strip placement groove.

3. The enzymatic color detection structure of claim 1 or 2, wherein the enzymatic color detection structure is integrally formed.

4. The enzymatic color detecting structure of claim 1 or 2, wherein the photodiode receiving hole portion (101) is a trumpet-shaped through hole having a small top and a wide bottom.

5. The enzymatic color detection structure according to claim 1 or 2, wherein screw fixing holes (106) fixedly connected with the detection PCB are formed at four corners of the bottom of the enzymatic color detection structure.

6. The enzymatic color detection structure of claim 1 or 2, wherein the photodiode receiving portion is located right above a photodiode disposed on the fixedly attached detection PCB.

7. The enzymatic color detection structure of claim 1 or 2, wherein the LED light-transmitting groove is located above the LED disposed on the fixedly connected detection PCB.