CN211847935U

CN211847935U - Cell culture ware with protective structure and based on micro-fluidic chip

Info

Publication number: CN211847935U
Application number: CN202020180304.1U
Authority: CN
Inventors: 严冬旺; 赵森林; 彭志海; 孙红成; 李大卫; 陈佳益
Original assignee: Shanghai First Peoples Hospital
Current assignee: Shanghai First Peoples Hospital
Priority date: 2020-02-18
Filing date: 2020-02-18
Publication date: 2020-11-03
Anticipated expiration: 2030-02-18

Abstract

The utility model discloses a cell culture household utensils with protective structure and based on micro-fluidic chip, including base, connector, micro-fluidic chip, wall cover and closing cap, the front of base is provided with the connector, the intermediate position department of base upper surface inlays and has micro-fluidic chip, the last surface bonding of base has the wall cover, the top lid of wall cover has closed the closing cap, the lateral wall parcel of closing cap has the rubber buffering ring, the lower surface paste of counter weight seat has the anti-skidding cushion, the spread groove has been seted up to the intermediate position department of counter weight seat lower surface, the inside of spread groove is pasted and is had the liquid bag, the bead department of wall cover is pasted and is had the beaded finish. The utility model discloses increase and to have protective structure, promoted holistic protectiveness, strengthened being connected between closing cap and the wall cover, the culture solution outflows when avoiding falling, increases and has counter weight seat, anti-skidding cushion and beaded finish, places more stably, avoids the mistake to touch and falls down.

Description

Cell culture ware with protective structure and based on micro-fluidic chip

Technical Field

The utility model relates to a cell culture ware technical field specifically is a cell culture ware with protective structure and based on micro-fluidic chip.

Background

Along with the continuous development of science, the society makes continuous progress, often need carry out cell culture in biology, need use the cell culture dish in this process, for better study, people use micro-fluidic chip technique on the cell culture dish, strengthen the authenticity of research result, but current cell culture dish does not set up protective structure, fall easily and smash, influence the practicality of device, when falling, the easy separation between closing cap and the wall cover, inside culture solution flows easily, need follow the cell culture that newly carries on.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a cell culture household utensils with protective structure and based on micro-fluidic chip does not set up protective structure in order to solve what provide among the above-mentioned background art, separates easily between closing cap and the wall cover, the easy problem that flows of inside culture solution.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a cell culture household utensils with protective structure and based on micro-fluidic chip, includes base, connector, micro-fluidic chip, wall cover and closing cap, the front of base is provided with the connector, the intermediate position department of base upper surface inlays and has micro-fluidic chip, the last surface bonding of base has the wall cover, the top lid of wall cover has closed the closing cap, the lateral wall parcel of closing cap has the rubber cushion ring, the lower surface of base is pasted and is had the counter weight seat, the lower surface of counter weight seat is pasted and is had the anti-skidding cushion, the intermediate position department of counter weight seat lower surface has seted up the spread groove, the inside of spread groove is pasted and is had the liquid bag, the bead department of wall cover is pasted and is had the beaded finish, the welding of beaded finish outer wall has the connection auricle, the storage bin has been seted up to the inside of closing cap, the auricle is.

Preferably, the output end of the microfluidic chip is electrically connected with the connecting port through a lead.

Preferably, the outer wall equidistance of wall cover is provided with the reinforcing piece, reinforcing piece and wall cover adopt the mode of sintering to be connected.

Preferably, the inner side of the reinforcing ring is provided with a welt, and the outer diameter of the welt is equal to the inner diameter of the wall sleeve.

Preferably, there are 4 connection lugs, and the connection lugs are distributed in an annular array.

Preferably, the outer wall of the base is provided with a semicircular groove, the inner wall of the semicircular groove is pressed with a metal nesting sleeve, and the inside of the sealing cover is adhered with a connecting embedded ring which is connected with the metal nesting sleeve.

Compared with the prior art, the beneficial effects of the utility model are that: this cell culture household utensils with protective structure and based on micro-fluidic chip increases there is protective structure, has promoted holistic protectiveness, has strengthened the closing cap and has connected between the wall cover, and the culture solution outflows when avoiding falling, increases and has counter weight seat, anti-skidding cushion and beaded finish, places more stably, avoids the mistake to touch and falls.

Be provided with reinforcing plate, beaded finish, rubber buffering ring and metal nestification, the diameter of the border of closing cap and rubber buffering ring and base all is greater than the diameter of wall cover, the wall cover be difficult for with ground direct contact, reinforcing plate and beaded finish have promoted the intensity of wall cover for the protectiveness obtains promoting.

Be provided with connection auricle, collecting storage, connection ring and metal nestification, strengthened the frictional force between closing cap and the wall cover for the lid closes inseparabler between wall cover and the closing cap, and the closing cap appears separating with the wall cover when avoiding dropping, strengthens the protection to the culture solution.

Be provided with counter weight seat, anti-skidding cushion and liquid bag, the counter weight seat has increased the holistic weight of device, and anti-skidding cushion and liquid bag have promoted laminating degree and frictional force between device and the desktop, avoid the device to receive the mistake and touch and fall.

Drawings

FIG. 1 is a schematic front view of the structure of the present invention;

FIG. 2 is a schematic sectional view of the front view of the structure of the present invention;

FIG. 3 is an enlarged schematic view of the structure at A in FIG. 2 according to the present invention;

fig. 4 is a schematic top view of the structure of the base and the wall cover of the present invention.

In the figure: 1. a base; 2. a connecting port; 3. a microfluidic chip; 4. a wall sleeve; 5. a reinforcing sheet; 6. sealing the cover; 7. a rubber cushion ring; 8. a counterweight seat; 9. an anti-slip rubber pad; 10. connecting grooves; 11. a reinforcement ring; 12. connecting a lug plate; 13. a storage bin; 14. nesting metal; 15. connecting the embedded ring; 16. liquid bag.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-4, the present invention provides an embodiment: a cell culture vessel with a protective structure and based on a microfluidic chip comprises a base 1, a connecting port 2, the microfluidic chip 3, a wall sleeve 4 and a sealing cover 6, wherein the connecting port 2 is arranged on the front surface of the base 1, the microfluidic chip 3 is embedded in the middle position of the upper surface of the base 1, the type of the microfluidic chip 3 can be cchip, the microfluidic chip adopts PDMS material, the PDMS material has the characteristics of high transparency, elasticity, air permeability, good chemical inertness, strong repeatability and the like, and is very suitable for relevant microfluidic scientific research experiments, such as cell culture, drug screening, cell capture and other relevant biochemical experiments, the material has hydrophobic property, can be flexibly modified by chemical or physical methods to eliminate cell nonspecific adsorption and the like, the output end of the microfluidic chip 3 is electrically connected with the connecting port 2 through a lead and is connected with the connecting port 2 through a connecting line, the information that will receive micro-fluidic chip 3 on the computer is analyzed, and the research result is more true, and the upper surface bonding of base 1 has wall cover 4, and the outer wall equidistance of wall cover 4 is provided with strengthens piece 5, strengthens piece 5 and wall cover 4 adoption sintered mode and is connected, strengthens 5 sintering backs of piece and wall cover 4 and fuses into an organic whole, has increased the intensity on the 5 vertical direction of enhancement piece, and is broken when avoiding wall cover 4 to fall, has strengthened the protectiveness.

The top lid of wall cover 4 has closed closing cap 6, the lateral wall parcel of closing cap 6 has rubber buffering ring 7, base 1's lower surface is pasted and is had counter weight seat 8, counter weight seat 8's lower surface is pasted and is had anti-skidding cushion 9, connecting groove 10 has been seted up to the intermediate position department of counter weight seat 8 lower surface, connecting groove 10's inside is pasted and is had liquid bag 16, wall cover 4's bead department is pasted and is had beaded finish 11, the inboard of beaded finish 11 is provided with the hem border, and the hem border external diameter equals with wall cover 4's internal diameter, through increasing beaded finish 11 in wall cover 4 bead department, the material of beaded finish 11 is the metal, the intensity of base 1 bead has been promoted, and the hem border internal card of beaded finish 11 has strengthened the laminating degree between beaded finish 11 and the wall cover 4, the support to wall cover 4 open-ended has been promoted.

The welding of 11 outer walls of beaded finish has auricle 12, auricle 12 is provided with 4, auricle 12 is the distribution of annular array, all be in the block state in four directions, strengthen stability, storage chamber 13 has been seted up to the inside of closing cap 6, auricle 12 is connected with storage chamber 13, when the lid closes, align storage chamber 13 with auricle 12, ensure that storage chamber 13 is connected with auricle 12, when the culture dish falls, closing cap 6 appears becoming flexible with wall cover 4, because auricle 12 blocks inside storage chamber 13, make closing cap 6 difficult and wall cover 4 break away from, avoid culture solution and cell outflow.

The semicircular groove has been seted up to base 1's outer wall, and the inner wall pressfitting in semicircular groove has metal nested 14, the inside of closing cap 6 is pasted and is had connection abaculus ring 15, connect abaculus ring 15 and metal nested 14 and be connected, the leakproofness has been increased, increase coefficient of friction, connect after abaculus ring 15 is connected with metal nested 14, cooperation auricle 12 and the 13 block structure of collecting bin, make closing cap 6 be difficult for appearing turning over, avoid closing cap 6 and wall cover 4 separation, strengthen the protection to culture solution and cell.

The working principle is as follows: during the use, at first to the inside cell culture liquid that adds of wall cover 4, add the cell specimen that needs to cultivate to wall cover 4 inside next, the closing lid 6 that closes is closed to the lid, need align collecting chamber 13 and connection auricle 12 when closing, ensures that the connection auricle 12 is connected with collecting chamber 13 after closing, and the connection after closing is built-in and inside metal nest 14, has strengthened the accuracy of being connected between closing lid 6 and the wall cover 4 in the embedded 15 that connects.

Place the culture dish when the desktop, because base 1 lower surface increases there is counter weight seat 8, anti-skidding cushion 9 and liquid bag 16, counter weight seat 8 has increased the holistic weight of device for the whole center of device moves down, and is more stable, and anti-skidding cushion 9 and liquid bag 16 all are the rubber material, have increased the coefficient of friction between culture dish and the desktop, and liquid bag 16 and anti-skidding cushion 9 all possess deformability, laminate more with the desktop, are difficult for appearing the gap.

When the culture dish falls, because closing cap 6 and rubber buffer ring 7 and base 1's setting, make wall cover 4 can not direct and ground contact, strengthened piece 5 and beaded finish respectively increased simultaneously at wall cover 4 outer wall and bead, strengthen wall cover 4, wall cover 4 is broken when avoiding falling, the closing cap 6 that the lid closed simultaneously, it is connected with metal nestification 14 to connect the embedded ring 15, it is connected with storage cabin 13 to connect auricle 12, make closing cap 6 difficult the appearance to turn over, avoid closing cap 6 and wall cover 4 to separate, strengthen the protection to culture solution and cell.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. The utility model provides a cell culture household utensils with protective structure and based on micro-fluidic chip, includes base (1), connector (2), micro-fluidic chip (3), wall cover (4) and closing cap (6), its characterized in that: the front of the base (1) is provided with a connecting port (2), the middle position of the upper surface of the base (1) is inlaid with a micro-fluidic chip (3), the upper surface of the base (1) is bonded with a wall sleeve (4), the top end of the wall sleeve (4) is covered with a sealing cover (6), the side wall of the sealing cover (6) is wrapped with a rubber buffer ring (7), the lower surface of the base (1) is bonded with a counterweight seat (8), the lower surface of the counterweight seat (8) is bonded with an anti-skid rubber pad (9), the middle position of the lower surface of the counterweight seat (8) is provided with a connecting groove (10), the inside of the connecting groove (10) is bonded with a liquid bag (16), the edge opening of the wall sleeve (4) is bonded with a reinforcing ring (11), the outer wall of the reinforcing ring (11) is welded with a connecting lug (12), the inside of the sealing cover (6) is provided with a containing bin (, the connecting lug (12) is connected with the storage bin (13).

2. A cell culture vessel with a protective structure based on a microfluidic chip according to claim 1, wherein: the output end of the micro-fluidic chip (3) is electrically connected with the connecting port (2) through a lead.

3. A cell culture vessel with a protective structure based on a microfluidic chip according to claim 1, wherein: the outer wall equidistance of wall cover (4) is provided with reinforcing piece (5), reinforcing piece (5) and wall cover (4) adopt the sintered mode to be connected.

4. A cell culture vessel with a protective structure based on a microfluidic chip according to claim 1, wherein: the inner side of the reinforcing ring (11) is provided with a welt, and the outer diameter of the welt edge is equal to the inner diameter of the wall sleeve (4).

5. A cell culture vessel with a protective structure based on a microfluidic chip according to claim 1, wherein: the number of the connecting lug plates (12) is 4, and the connecting lug plates (12) are distributed in an annular array.

6. A cell culture vessel with a protective structure based on a microfluidic chip according to claim 4, wherein: the outer wall of the base (1) is provided with a semicircular groove, the inner wall of the semicircular groove is pressed with a metal nesting sleeve (14), the inside of the sealing cover (6) is pasted with a connecting embedded ring (15), and the connecting embedded ring (15) is connected with the metal nesting sleeve (14).