CN211847899U

CN211847899U - Reagent box

Info

Publication number: CN211847899U
Application number: CN202020150681.0U
Authority: CN
Inventors: 杨文山; 林清格; 李馥君; 周品兴; 蔡汮龙; 李佩瑜; 张晓芬
Original assignee: Genereach Biotechnology Corp
Current assignee: Genereach Biotechnology Corp
Priority date: 2020-02-03
Filing date: 2020-02-03
Publication date: 2020-11-03
Anticipated expiration: 2030-02-03

Abstract

A reagent cassette includes a first positioning portion, a second positioning portion, and a plurality of reagent slots. The second positioning portion is opposite to the first positioning portion in a longitudinal direction, and a shape of the second positioning portion is different from a shape of the first positioning portion. The reagent grooves are arranged along the length direction and are arranged between the first positioning part and the second positioning part, the top end of each reagent groove is open, the bottom end of each reagent groove is closed, the foolproof installation effect can be generated by the aid of the design of the different shapes of the first positioning part and the second positioning part, a user can accurately and quickly assemble the first positioning part and the second positioning part into the installation groove of the extraction frame, the reagent grooves are in single-row arrangement structural design, are small in size and convenient to carry, and are suitable for first-line occasions outside laboratories.

Description

Reagent box

Technical Field

The utility model relates to a tool for extracting nucleic acid, in particular to a reagent box.

Background

Referring to fig. 1, a conventional deep well plate 1 that can be placed on a biochemical reactor (e.g., a nucleic acid purification apparatus, not shown) for nucleic acid extraction is provided, the deep well plate 1 has a plurality of reagent wells 101 arranged in a matrix, and a user drops reagents into the reagent wells 101 manually.

Although the deep hole plate 1 is bulky and can be stably placed on the biochemical reactor, because the deep hole plate 1 occupies a large space, the deep hole plate 1 is only suitable for the indoor environment of a laboratory and is not convenient to carry, and is not suitable for the first-line occasions outside the laboratory, such as a quarantine site or a forensic site in the breeding industry.

Further, even if such a deep well plate 1 performs a small-scale extraction operation using only a part of the reagent vessels 101 (for example, one row), the whole deep well plate can be discarded after use, and is not environmentally friendly in use.

Disclosure of Invention

It is therefore an object of the present invention to provide a reagent cartridge that overcomes at least one of the disadvantages of the prior art.

Therefore, the reagent cartridge of the present invention comprises a first positioning portion, a second positioning portion, and a plurality of reagent chambers.

The second positioning portion is opposite to the first positioning portion in a longitudinal direction, and a shape of the second positioning portion is different from a shape of the first positioning portion.

The reagent grooves are arranged along the length direction and between the first positioning part and the second positioning part, the top end of each reagent groove is open, and the bottom end of each reagent groove is closed.

The utility model discloses reagent casket still contains the casket body, and several cell body, the casket body include the front end wall length direction on the contrary in the rear end wall of front end wall, and two connect in the front end wall with between the rear end wall and perpendicular to length direction's horizontal direction is last each other looks spaced lateral wall, the cell body is respectively around defining out the reagent groove, most adjacent to one of them cell body of front end wall including expose in the front end wall with the wall that exposes outside the lateral wall, first location portion be formed in expose the wall, second location portion by the lateral wall is adjacent to the partial cooperation of rear end wall the rear end wall forms, and remaining cell body is in length direction in between the front and rear end wall, and in the horizontal direction in between the lateral wall.

The utility model discloses reagent casket, the outline semicircular in shape of the cross section of first location portion, the outline of the cross section of second location portion is the U style of calligraphy.

The utility model discloses reagent casket, the front end wall have be located in the length direction last wall portion before one of them cell body, and two are less than in the direction of height go up wall portion and be located respectively expose the lower wall portion of wall both sides, the direction of height perpendicular to length direction with the horizontal direction, it is in to expose the wall be less than in the direction of height go up wall portion.

The utility model discloses reagent casket, the casket body still including set up in the front end wall grips the piece forward convex preceding, and set up in the rear end wall grips the piece backward convex back.

The utility model discloses reagent casket, the casket body still includes the edge the first reinforcement wall that length direction extends, and the several is in interval setting and edge on the length direction the transverse direction extend in second reinforcement wall between the lateral wall, first reinforcement wall with the bottom of cell body is connected, and with the back end wall is connected, the second reinforcement wall with first reinforcement wall is crisscross mutually, the second reinforcement wall respectively with the bottom of all the other cell bodies is connected.

The utility model discloses reagent casket, reagent casket still contains third location portion, third location portion is in the perpendicular to compare in length direction's direction of height first location portion is farther away from in most adjacent to the bottom in one of them reagent groove of first location portion.

The utility model discloses reagent casket still contains fourth location portion, fourth location portion is in on the direction of height than second location portion is farther away from in most adjacent to the bottom in another reagent groove of second location portion.

The utility model discloses reagent casket, the shape of third location portion, fourth location portion is the V style of calligraphy.

The reagent box of the utility model also comprises a box body and a plurality of groove bodies, wherein the box body comprises a front end wall, a rear end wall which is opposite to the front end wall in the length direction, and two side walls which are connected between the front end wall and the rear end wall and are mutually spaced in the transverse direction which is perpendicular to the length direction and the height direction, the groove bodies respectively surround and define the reagent groove, one groove body which is most adjacent to the front end wall comprises an exposed wall which is exposed outside the front end wall and the side wall, the rest groove bodies are arranged between the front end wall and the rear end wall in the length direction and between the side walls in the transverse direction, the first positioning part is formed on the exposed wall, the second positioning part is formed by matching the part of the side wall which is adjacent to the rear end wall with the rear end wall, and the third positioning part is arranged on the exposed wall, the fourth positioning portion is provided to the rear end wall.

The utility model has the advantages that: the utility model discloses utilize the design of first location portion, second location portion different shapes can produce the effect of preventing slow-witted installation, help the user correctly and will fast in the mounting groove of extraction frame is assembled to first location portion, second location portion, moreover, the utility model discloses a reagent groove is the structural design who is single-row range, and is small and portable, is applicable to the first line occasion outside the laboratory, in addition, the utility model discloses convenient to use person carries out small-scale nucleic acid extraction operation, after using, can not produce the hole site in reagent groove that does not use, and is equivalent environmental protection in the use.

Drawings

Fig. 1 is a perspective view of a prior art deep hole plate;

FIG. 2 is a perspective view of a reagent cartridge of the present invention mounted to a biochemical reactor by an extraction rack;

FIG. 3 is an exploded perspective view of the embodiment and the extraction rack;

FIG. 4 is a view similar to FIG. 3, but from another angle;

FIG. 5 is an exploded perspective view of the embodiment;

FIG. 6 is a view similar to FIG. 5, but from another angle, with the release liner of this embodiment removed;

FIG. 7 is another perspective view of the embodiment;

FIG. 8 is an assembled sectional view of the embodiment and the extraction rack;

fig. 9 is a sectional view taken along line ix-ix in fig. 8.

Detailed Description

The present invention will be described in detail with reference to the accompanying drawings and examples.

Referring to fig. 2, 3 and 4, in an embodiment of the reagent cartridge 100 of the present invention, the reagent cartridge 100 may be mounted on an extraction rack 200 for performing nucleic acid extraction in a biochemical reactor 300, the extraction rack 200 has a plurality of mounting grooves 210 and a plurality of V-shaped slots 220, each mounting groove 210 has a front slot portion 211 with a semicircular outer contour in cross section and a rear slot portion 212 with a U-shaped outer contour in cross section, and each slot 220 communicates with the front slot portion 211 of the respective mounting groove 210.

As shown in FIGS. 5, 6 and 7, the reagent cassette 100 comprises a cassette body 10, a plurality of grooves 20I, 20 II, 20 III, 20 IV, 20V, 20 VI and 20 VII, and a release paper 30.

The box 10 includes a front end wall 11, a rear end wall 12 opposite to the front end wall 11 in a longitudinal direction X, two side walls 13 connected between the front end wall 11 and the rear end wall 12 and spaced apart from each other in a transverse direction Y perpendicular to the longitudinal direction X, a first reinforcing wall 14 extending along the longitudinal direction X, a plurality of second reinforcing walls 15 spaced apart from each other in the longitudinal direction X and extending between the side walls 13 in the transverse direction Y, a front holding block 16 disposed on the front end wall 11 and protruding forward, and a rear holding block 17 disposed on the rear end wall 12 and protruding rearward.

The front end wall 11 has an upper wall portion 111 located in front of one of the slots 20 i in the length direction X, and two lower wall portions 112 located lower than the upper wall portion 11 in a height direction Z perpendicular to the length direction X and the transverse direction Y.

The first reinforcing wall 14 is connected to the bottom ends of the tank bodies 20 i, 20 ii, 20 iii, 20 iv, 20 v, 20 vi, 20 vii, and is connected to the rear end wall 12, the second reinforcing wall 15 is staggered with the first reinforcing wall 14, and the second reinforcing wall 15 is connected to the bottom ends of the remaining tank bodies 20 ii, 20 iii, 20 iv, 20 v, 20 vi, 20 vii, respectively. The first reinforcing wall 14 and the second reinforcing wall 15 can increase the structural stability of the reagent cartridge 100.

The front holding block 16 and the rear holding block 17 can facilitate the user to take the reagent cartridge 100.

The one of the slots 20 i closest to the front end wall 11 includes an exposed wall 21 exposed from the front end wall 11 and the side walls 13, the exposed wall 21 is lower than the upper wall 111 in the height direction Z, the lower walls 112 are respectively located at two sides of the exposed wall 21, and the rest of the slots 20 ii, 20 iii, 20 iv, 20 v, 20 vi, 20 vii are located between the front and

rear end walls

11, 12 in the length direction X and between the side walls 13 in the transverse direction Y.

Each of the housing bodies 20I, 20 II, 20 III, 20 IV, 20V, 20 VI, 20 VII defines a reagent vessel 22 for filling with a reagent, the reagent vessel 22 of each of the housing bodies 20I, 20 II, 20 III, 20 IV, 20V, 20 VI, 20 VII being open at the top end thereof, and the reagent vessel 22 of each of the housing bodies 20I, 20 II, 20 III, 20 IV, 20V, 20 VI, 20 VII being closed at the bottom end thereof.

The release paper 30 is detachably disposed at the top end of the container 10, the reagent containers 22 of the container bodies 20 i, 20 ii, 20 iii, 20 iv, 20 v, 20 vi, 20 vii are sealed to seal the reagents in the reagent containers 22 of the container bodies 20 i, 20 ii, 20 iii, 20 iv, 20 v, 20 vi, 20 vii, and the release paper 30 is torn off when the reagent containers are to be used.

The reagent cassette 100 has a first positioning portion 40, a second positioning portion 50, a third positioning portion 60, and a fourth positioning portion 70.

In the present embodiment, the first positioning portion 40 is formed on the exposed wall 21, and the outer contour of the cross section of the first positioning portion 40 is semicircular.

The second positioning portion 50 is opposite to the first positioning portion 40 in the longitudinal direction X, and the shape of the second positioning portion 50 is different from the shape of the first positioning portion 40. In the present embodiment, the second positioning portion 50 is formed by the portion of the side wall 13 adjacent to the rear end wall 12 and the rear end wall 12, the outer contour of the cross section of the second positioning portion 50 is U-shaped, and the reagent grooves 22 of the groove bodies 20 i, 20 ii, 20 iii, 20 iv, 20 v, 20 vi, 20 vii are arranged along the length direction X and between the first positioning portion 40 and the second positioning portion 50.

In the present embodiment, the third positioning portion 60 is disposed on the exposed wall 21, and the shape of the third positioning portion 60 is V-shaped, as shown in fig. 8, the third positioning portion 60 is farther away from the bottom end of the reagent tank 22 of the one tank body 20 i most adjacent to the first positioning portion 40 than the first positioning portion 40 in the height direction Z.

As shown in fig. 5, 6 and 7, in the present embodiment, the fourth positioning portion 70 is disposed on the rear end wall 12, the shape of the fourth positioning portion 70 is V-shaped, and as shown in fig. 8, the fourth positioning portion 70 is farther away from the bottom end of the reagent vessel 22 of the other vessel body 20 vii most adjacent to the second positioning portion 50 than the second positioning portion 50 in the height direction Z.

Therefore, as shown in fig. 3, 8 and 9, when a user wants to mount the reagent cartridge 100 in one of the mounting slots 210 of the extraction rack 200, the first positioning portion 40 and the second positioning portion 50 with different shapes can allow the user to correctly assemble the first positioning portion 40 and the second positioning portion 50 into the front slot portion 211 and the rear slot portion 212 of the one of the mounting slots 210, respectively, and at this time, the third positioning portion 60 is inserted into one of the slots 220 corresponding to the one of the mounting slots 210, so as to perform a positioning function.

Through the above description, the advantages of the present invention can be summarized as follows:

firstly, the utility model discloses utilize this first location portion 40, the second location portion 50 of different shapes can produce the effect of preventing slow-witted installation, help the user correctly and organize into the preceding slot part 211 of this one of them mounting groove 210, back slot part 212 with this first location portion 40, second location portion 50 respectively fast, moreover, this third location portion 60 can the inlay card in this one of them draw-in groove 220, and produce the effect of location to improve the stability that this reagent casket 100 carries out the nucleic acid extraction operation on this biochemical reactor 300.

Two, compare in prior art, the utility model discloses a cell body 20I, 20 II, 20 III, 20 IV, 20V, 20 VI, 20 VII are the structural design who is the single-row range, the utility model discloses a small does not account for the space, and portable is applicable to the first line occasion outside the laboratory fairly, for example the field of aquaculture quarantine or the forensic scene.

Thirdly, compare in prior art, the utility model discloses convenient to use person carries out small-scale nucleic acid extraction operation, after using, can not leave the hole site of unused reagent groove 22, and is fairly environmental protection in the use.

To sum up, the reagent box of the utility model can be fool-proof when being installed, is small in size and easy to carry, and is suitable for the first line of occasions outside the laboratory, so that the purpose of the utility model can be achieved.

Claims

1. A reagent cartridge comprising a plurality of reagent wells, wherein:

the reagent box also comprises a first positioning part and a second positioning part;

the second positioning portion is opposite to the first positioning portion in a longitudinal direction, and the shape of the second positioning portion is different from the shape of the first positioning portion; and

2. The reagent cartridge of claim 1, wherein: the reagent box also comprises a box body and a plurality of groove bodies, wherein the box body comprises a front end wall, a rear end wall opposite to the front end wall in the length direction, and two side walls which are connected between the front end wall and the rear end wall and are mutually spaced in the transverse direction perpendicular to the length direction, the groove bodies respectively surround and define the reagent grooves, one groove body closest to the front end wall comprises an exposed wall exposed outside the front end wall and the side walls, the first positioning part is formed on the exposed wall, the second positioning part is formed by matching the part of the side wall adjacent to the rear end wall with the rear end wall, and the rest groove bodies are arranged between the front end wall and the rear end wall in the length direction and between the side walls in the transverse direction.

3. The reagent cartridge of claim 2, wherein: the outer contour of the cross section of the first positioning part is semicircular, and the outer contour of the cross section of the second positioning part is U-shaped.

4. The reagent cartridge of claim 3, wherein: the front end wall is provided with an upper wall portion located in front of one of the groove bodies in the length direction, and two lower wall portions which are lower than the upper wall portion in the height direction and located on two sides of the exposed wall respectively, the height direction is perpendicular to the length direction and the transverse direction, and the exposed wall is lower than the upper wall portion in the height direction.

5. The reagent cartridge of claim 2, wherein: the box body also comprises a front holding block which is arranged on the front end wall and protrudes forwards, and a rear holding block which is arranged on the rear end wall and protrudes backwards.

6. The reagent cartridge of claim 2, wherein: the box body further comprises a first reinforcing wall extending along the length direction, and a plurality of second reinforcing walls which are arranged at intervals on the length direction and extend between the side walls along the transverse direction, the first reinforcing walls are connected with the bottom end of the groove body and connected with the rear end wall, the second reinforcing walls are staggered with the first reinforcing walls, and the second reinforcing walls are respectively connected with the bottom ends of the rest groove bodies.

7. The reagent cartridge of claim 1, wherein: the reagent cassette further comprises a third positioning part, and the third positioning part is farther from the bottom end of one of the reagent grooves which is most adjacent to the first positioning part than the first positioning part in the height direction perpendicular to the length direction.

8. The reagent cartridge of claim 7, wherein: the reagent cassette further includes a fourth positioning portion that is farther from a bottom end of another reagent tank that is closest to the second positioning portion than the second positioning portion in the height direction.

9. The reagent cartridge of claim 8, wherein: the third positioning part and the fourth positioning part are V-shaped.

10. The reagent cartridge of claim 8, wherein: the reagent box also comprises a box body and a plurality of groove bodies, wherein the box body comprises a front end wall, a rear end wall opposite to the front end wall in the length direction, and two side walls which are connected between the front end wall and the rear end wall and are mutually spaced in the transverse direction perpendicular to the length direction and the height direction, the groove bodies respectively surround and define the reagent grooves, one groove body which is most adjacent to the front end wall comprises an exposed wall exposed outside the front end wall and the side walls, the rest groove bodies are arranged between the front end wall and the rear end wall in the length direction and between the side walls in the transverse direction, the first positioning part is formed on the exposed wall, the second positioning part is formed by matching the part of the side wall which is adjacent to the rear end wall with the rear end wall, and the third positioning part is arranged on the exposed wall, the fourth positioning portion is provided to the rear end wall.